hydroxyproline has been researched along with Silicosis in 73 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Silicosis: A form of pneumoconiosis resulting from inhalation of dust containing crystalline form of SILICON DIOXIDE, usually in the form of quartz. Amorphous silica is relatively nontoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Also, the effects of Pirfenidone on macrophage polarization and pulmonary fibrosis were evaluated in silicosis with early intervention and late treatment by histological examination, Enzyme-linked immunosorbent assay, Hydroxyproline assay, Western blot and Quantitative reverse transcription polymerase chain reaction." | 8.12 | Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways. ( Bo, C; Jia, Q; Li, M; Tang, Q; Xing, C; Zhang, Z, 2022) |
| " Different doses of dioscin were gavaged to the animals 1 day after crystalline silica instillation to see the effect of dioscin on crystalline silica induced pulmonary fibrosis." | 7.85 | Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice. ( Chen, J; Chen, Y; Du, S; Li, C; Li, S; Liu, F; Lu, Y; Weng, D; Zhang, Y, 2017) |
| "To observe the expression of leptin (LP) and its influence on pulmonary fibrosis in experimental rats with silicosis and the correlation between the expressions of leptin and HIF-1α." | 7.80 | [Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions]. ( Chen, B; Fan, D; Li, H; Li, Y; Pei, H; Zhang, M; Zhou, R; Zhu, S, 2014) |
| "Fasting urinary hydroxyproline: creatinine (HOP:C) ratios were measured in 74 patients with suspected (borderline) silicosis (10), simple silicosis (46) and complicated silicosis (9 silicotuberculosis, 4 massive fibrosis, and 5 combined silicotuberculosis and massive fibrosis) and in 18 healthy subjects (controls)." | 7.67 | Fasting urinary hydroxyproline: creatinine ratios in silicosis. ( Chan, SL; Jones, MG; Ng, TP; Pang, CP, 1989) |
| " Interview examination with BMRC questionnaire, X-ray examination and measurement of urinary hydroxyproline to creatinine ratio (HOP ratio) were carried out in order to elucidate the relationship between silicosis and urinary HOP ratio and to demonstrate the effect of smoking on pneumofibrosis." | 7.67 | [Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis]. ( Kasuga, H; Kato, Y; Matsuki, H; Osaka, F; Shima, S, 1986) |
| " Additionally, FcεRI-deficient mice showed a significantly lower score of pulmonary fibrosis than wild-type mice following exposure to silica, with significantly lower hydroxyproline content and expression of fibrotic genes Col1a1 and Fn1." | 4.12 | FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis. ( Chen, Y; Hou, L; Hu, H; Jiang, X; Li, Z; Pang, J; Song, M; Wang, C; Wang, J; Yang, J; Yang, P; Zhang, H; Zhang, T; Zhang, Z; Zou, X, 2022) |
| " Also, the effects of Pirfenidone on macrophage polarization and pulmonary fibrosis were evaluated in silicosis with early intervention and late treatment by histological examination, Enzyme-linked immunosorbent assay, Hydroxyproline assay, Western blot and Quantitative reverse transcription polymerase chain reaction." | 4.12 | Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways. ( Bo, C; Jia, Q; Li, M; Tang, Q; Xing, C; Zhang, Z, 2022) |
| " In vivo, intratracheal treatment with Lv-miR-29c significantly increased expression of miR-29c, and reduced expression of β-catenin, matrix metalloproteinase (MMP)-2, and MMP-9 in the lung and levels of transforming growth factor-beta 1 (TGF-β1) and interleukin-6 (IL-6) in bronchoalveolar lavage fluid, and notably attenuated pulmonary fibrosis as evidenced by hydroxyproline content in silica-administered mice." | 3.88 | Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice. ( Liu, J; Wang, FS; Wang, X; Xu, K; Yang, XY; Zeng, Q, 2018) |
| " Different doses of dioscin were gavaged to the animals 1 day after crystalline silica instillation to see the effect of dioscin on crystalline silica induced pulmonary fibrosis." | 3.85 | Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice. ( Chen, J; Chen, Y; Du, S; Li, C; Li, S; Liu, F; Lu, Y; Weng, D; Zhang, Y, 2017) |
| "To observe the expression of leptin (LP) and its influence on pulmonary fibrosis in experimental rats with silicosis and the correlation between the expressions of leptin and HIF-1α." | 3.80 | [Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions]. ( Chen, B; Fan, D; Li, H; Li, Y; Pei, H; Zhang, M; Zhou, R; Zhu, S, 2014) |
| " Positive correlations were seen between hydroxyproline (as an index of fibrosis), silica dust, non-silica inorganic dust, radiographic category of pneumoconiosis and pathologic grade of silicosis." | 3.74 | Dust content of lungs and its relationships to pathology, radiology and occupational exposure in Ontario hardrock miners. ( Muir, DC; Ritchie, AC; Verma, DK, 2008) |
| "08 U) or silica (2 mg) to mice leads, after 15 days, to a patchy pulmonary fibrosis associated with a significant increase of the lung hydroxyproline." | 3.69 | Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. ( Piguet, PF; Vesin, C, 1994) |
| "We tested the efficacy of 2 antifibrotic agents, the proline analogue cis-4-hydroxy-L-proline (cHyp) and the lathyrogen beta-aminopropionitrile (BAPN), on experimental silicosis in hamsters." | 3.67 | Treatment of experimental silicosis with antifibrotic agents. ( Geismar, LS; Kerr, JS; Riley, DJ; Trelstad, RL, 1988) |
| " Interview examination with BMRC questionnaire, X-ray examination and measurement of urinary hydroxyproline to creatinine ratio (HOP ratio) were carried out in order to elucidate the relationship between silicosis and urinary HOP ratio and to demonstrate the effect of smoking on pneumofibrosis." | 3.67 | [Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis]. ( Kasuga, H; Kato, Y; Matsuki, H; Osaka, F; Shima, S, 1986) |
| "Silicosis is one of the most prevalent occupational lung diseases worldwide." | 1.39 | Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats. ( Gao, A; Niu, P; Tian, L; Wang, Y; Yang, G; Yang, J; Zhu, Z, 2013) |
| "Silicosis is a kind of pneumoconiosis caused by inhalation of silica dust, which is characterized by lung fibrosis." | 1.36 | A CD36 synthetic peptide inhibits silica-induced lung fibrosis in the mice. ( Chen, J; Chen, Y; Lv, L; Wang, X, 2010) |
| "Pulmonary silicosis is a deadly disease which kills thousands of people every year worldwide." | 1.36 | IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis. ( Chaudhury, BP; Chhabra, JK; Kumar, P; Mishra, V; Pandey, HP; Paul, B; Shukla, M; Tripathi, SS; Verma, M, 2010) |
| "Pulmonary fibrosis is a disabling consequence of many lung diseases but is difficult to quantify." | 1.31 | Quantitative image analysis of lung connective tissue in murine silicosis. ( Antonini, JM; Davis, GS; Hemenway, DR, 2000) |
| "Silicosis is a crippling fibrotic lung disease induced by inhalation of crystalline silica." | 1.31 | Immunoglobulin responses to experimental silicosis. ( Banks, DE; Huang, SH; Hubbs, AF; Ma, JK; Rojanasakul, Y; Schnabel, PC; Stanley, CF; Vallyathan, V; Weissman, DN, 2001) |
| "Silicosis is usually attributed to fibroblast stimulation by secretion of damaged alveolar macrophages (AMs), but the role of polymorphonuclear leukocytes (PMNs) and of continuing cell injury in the pathogenesis has not been fully studied." | 1.27 | Role of polymorphonuclear leukocytes in silica-induced pulmonary fibrosis. ( Adamson, IY; Bowden, DH, 1984) |
| "Hepatic silicosis was induced in rats by an intravenous injection of saline-suspended silica, 40 mg/kg of body weight." | 1.27 | Formation of granulomas in liver of silica-treated rats. ( Bartoś, F; Horský, J; Kanta, J; Korolenko, TA; Kovárová, H; Tilser, I, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (67.12) | 18.7374 |
| 1990's | 6 (8.22) | 18.2507 |
| 2000's | 6 (8.22) | 29.6817 |
| 2010's | 10 (13.70) | 24.3611 |
| 2020's | 2 (2.74) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 5 |
| Song, M | 1 |
| Li, Z | 1 |
| Hou, L | 1 |
| Zhang, H | 1 |
| Zhang, Z | 2 |
| Hu, H | 1 |
| Jiang, X | 1 |
| Yang, J | 2 |
| Zou, X | 1 |
| Pang, J | 1 |
| Zhang, T | 1 |
| Yang, P | 1 |
| Wang, J | 1 |
| Wang, C | 1 |
| Tang, Q | 1 |
| Xing, C | 1 |
| Li, M | 1 |
| Jia, Q | 1 |
| Bo, C | 1 |
| Li, C | 1 |
| Lu, Y | 1 |
| Du, S | 1 |
| Li, S | 1 |
| Zhang, Y | 1 |
| Liu, F | 1 |
| Weng, D | 1 |
| Chen, J | 5 |
| Wang, X | 3 |
| Xu, K | 1 |
| Yang, XY | 1 |
| Liu, J | 1 |
| Zeng, Q | 1 |
| Wang, FS | 1 |
| Zhu, Z | 1 |
| Yang, G | 1 |
| Wang, Y | 1 |
| Gao, A | 1 |
| Niu, P | 1 |
| Tian, L | 1 |
| Wang, YR | 1 |
| Yang, DY | 1 |
| Zhang, M | 3 |
| Pei, H | 1 |
| Li, Y | 1 |
| Fan, D | 1 |
| Zhu, S | 1 |
| Li, H | 1 |
| Chen, B | 1 |
| Zhou, R | 1 |
| Xiao, Y | 1 |
| Xia, H | 1 |
| Zhu, L | 1 |
| Li, X | 1 |
| Chen, R | 1 |
| Yin, X | 1 |
| Jiang, Z | 1 |
| Feng, L | 1 |
| Yu, M | 1 |
| Lou, J | 1 |
| Zhang, X | 1 |
| Lv, L | 1 |
| Ramsgaard, L | 1 |
| Englert, JM | 1 |
| Tobolewski, J | 1 |
| Tomai, L | 1 |
| Fattman, CL | 1 |
| Leme, AS | 1 |
| Kaynar, AM | 1 |
| Shapiro, SD | 1 |
| Enghild, JJ | 1 |
| Oury, TD | 1 |
| Tripathi, SS | 1 |
| Mishra, V | 1 |
| Shukla, M | 1 |
| Verma, M | 1 |
| Chaudhury, BP | 1 |
| Kumar, P | 1 |
| Chhabra, JK | 1 |
| Pandey, HP | 1 |
| Paul, B | 1 |
| Faxuan, W | 1 |
| Qin, Z | 1 |
| Dinglun, Z | 1 |
| Tao, Z | 1 |
| Xiaohui, R | 1 |
| Liqiang, Z | 1 |
| Yajia, L | 1 |
| BAILY, P | 1 |
| KILROE-SMITH, TA | 1 |
| HARINGTON, JS | 1 |
| VYSKOCIL, J | 1 |
| SKLENSKY, B | 1 |
| KATSNELSON, BA | 1 |
| BABUSHKINA, LG | 6 |
| VELICHKOVSKII, BT | 1 |
| BAUMANN, H | 1 |
| FRITZE, E | 1 |
| KALLWEIT, C | 1 |
| Dong, J | 2 |
| Liu, W | 1 |
| Jin, Y | 1 |
| Lakatos, HF | 1 |
| Burgess, HA | 1 |
| Thatcher, TH | 1 |
| Redonnet, MR | 1 |
| Hernady, E | 1 |
| Williams, JP | 1 |
| Sime, PJ | 1 |
| Verma, DK | 1 |
| Ritchie, AC | 1 |
| Muir, DC | 1 |
| Mansurova, ID | 1 |
| Nabidzhanova, EN | 1 |
| Slinchenko, NZ | 1 |
| Filipchenko, LL | 1 |
| Kostenko, TP | 1 |
| Gościcki, JW | 1 |
| Wiecek, E | 2 |
| Woźniak, H | 2 |
| Reiser, KM | 2 |
| Haschek, WM | 2 |
| Hesterberg, TW | 2 |
| Last, JA | 2 |
| Gross, KB | 1 |
| White, HJ | 1 |
| Smiler, KL | 1 |
| Zou, HR | 1 |
| Adamson, IY | 1 |
| Bowden, DH | 1 |
| Aronova, GV | 1 |
| Pawelec, D | 1 |
| Dettlaff, Z | 1 |
| Katsnel'son, BA | 1 |
| Kisklitsina, NS | 1 |
| Fed'kina, LG | 2 |
| Aretinskiĭ, BV | 2 |
| Piguet, PF | 1 |
| Vesin, C | 1 |
| Qin, XF | 1 |
| Liu, SJ | 1 |
| Ohtsuka, Y | 1 |
| Munakata, M | 1 |
| Ukita, H | 1 |
| Takahashi, T | 1 |
| Satoh, A | 1 |
| Homma, Y | 1 |
| Kawakami, Y | 1 |
| Huaux, F | 1 |
| Louahed, J | 1 |
| Hudspith, B | 1 |
| Meredith, C | 1 |
| Delos, M | 1 |
| Renauld, JC | 1 |
| Lison, D | 1 |
| Antonini, JM | 1 |
| Hemenway, DR | 1 |
| Davis, GS | 1 |
| Huang, SH | 1 |
| Hubbs, AF | 1 |
| Stanley, CF | 1 |
| Vallyathan, V | 1 |
| Schnabel, PC | 1 |
| Rojanasakul, Y | 1 |
| Ma, JK | 1 |
| Banks, DE | 1 |
| Weissman, DN | 1 |
| Kyselá, B | 1 |
| Weiss, Z | 1 |
| Skoda, V | 1 |
| Holusa, R | 4 |
| Heppleston, AG | 2 |
| Szymczykiewicz, K | 2 |
| Gościcki, J | 1 |
| Szendzikowski, S | 1 |
| Beletskii, VS | 1 |
| El'nichnykh, LN | 1 |
| Taceva, J | 1 |
| Zyłka-Włoszczyk, M | 1 |
| Ociepiński, M | 1 |
| Szaflarska-Stojko, E | 2 |
| Wocka-Marek, T | 1 |
| Zajac-Nedza, M | 1 |
| Zygan, U | 1 |
| Niedziela-Marx, J | 1 |
| Olczyk, K | 1 |
| Lukas, A | 1 |
| Morozova, KI | 1 |
| Ng, TP | 1 |
| Jones, MG | 1 |
| Pang, CP | 1 |
| Chan, SL | 1 |
| Dubois, F | 1 |
| Bégin, R | 1 |
| Cantin, A | 1 |
| Massé, S | 1 |
| Martel, M | 1 |
| Bilodeau, G | 1 |
| Dufresne, A | 1 |
| Perreault, G | 1 |
| Sébastien, P | 1 |
| Stepień, B | 1 |
| Vilím, V | 1 |
| Hurych, J | 1 |
| Callis, AH | 1 |
| Sohnle, PG | 1 |
| Mandel, GS | 1 |
| Mandel, NS | 1 |
| Kanta, J | 1 |
| Horský, J | 1 |
| Kovárová, H | 1 |
| Tilser, I | 1 |
| Korolenko, TA | 1 |
| Bartoś, F | 1 |
| Geismar, LS | 1 |
| Kerr, JS | 1 |
| Trelstad, RL | 1 |
| Riley, DJ | 1 |
| Osaka, F | 1 |
| Kasuga, H | 1 |
| Matsuki, H | 1 |
| Shima, S | 1 |
| Kato, Y | 1 |
| Chvapil, M | 2 |
| Lindy, S | 2 |
| Kahanpää, K | 2 |
| Karhunen, P | 2 |
| Halme, J | 2 |
| Uitto, J | 2 |
| Religa, Z | 1 |
| Maśliński, C | 1 |
| Kuncová, M | 2 |
| Havránková, J | 2 |
| Palecek, F | 2 |
| Kunc, L | 1 |
| Panfilova, GA | 1 |
| Dale, K | 1 |
| Shevchenko, AM | 1 |
| Gagauz, FG | 1 |
| Plishchenko, SS | 1 |
| Burrell, R | 1 |
| Anderson, M | 1 |
| Schlipköter, H | 1 |
| Grünspan, M | 1 |
| Dehnen, W | 1 |
| Mallner, B | 1 |
| Lapshin, EA | 1 |
| Gerasimenko, AA | 1 |
2 reviews available for hydroxyproline and Silicosis
| Article | Year |
|---|---|
Silica and asbestos: contrasts in tissue response.
Topics: Animals; Asbestos; Asbestosis; Cell Survival; Chick Embryo; Fibroblasts; Guinea Pigs; Humans; Hydrox | 1979 |
Observations on the mechanism of silicotic fibrogenesis.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Membrane Permeability; Cells, Cultured; Culture Media; | 1970 |
1 trial available for hydroxyproline and Silicosis
| Article | Year |
|---|---|
[Clinical studies on the elimination of hydroxyproline during treatment of silicosis in man with polyvinyl-pyridine-N-oxide (author's transl)].
Topics: Adult; Clinical Trials as Topic; Cyclic N-Oxides; Diet Therapy; Humans; Hydroxyproline; Middle Aged; | 1974 |
70 other studies available for hydroxyproline and Silicosis
| Article | Year |
|---|---|
FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis.
Topics: Animals; beta-N-Acetylhexosaminidases; Fibrosis; Histamine; Hydroxyproline; Immunoglobulin E; Interl | 2022 |
Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways.
Topics: Animals; Fibrosis; Hydroxyproline; Interleukin-18; Janus Kinase 2; Macrophages; Pneumonia; Pulmonary | 2022 |
Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice.
Topics: Animals; Blotting, Western; Diosgenin; Epithelial Cells; Female; Flow Cytometry; Hydroxyproline; Imm | 2017 |
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Topics: Airway Remodeling; Animals; beta Catenin; Disease Models, Animal; Female; Hydroxyproline; Interleuki | 2018 |
Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats.
Topics: Animals; Blotting, Western; Hydroxyproline; Lipid Peroxidation; Lung; Male; Oxidation-Reduction; Oxi | 2013 |
[The inhibitory effect of latent transforming growth factor β1 activation and silicosis by CD36 targeted RNA interference in silicosis model of rat].
Topics: Animals; Bronchoalveolar Lavage Fluid; CD36 Antigens; Disease Models, Animal; Female; Hydroxyproline | 2013 |
[Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions].
Topics: Animals; Blotting, Western; Collagen; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Hypoxia-Ind | 2014 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleu | 2015 |
A CD36 synthetic peptide inhibits silica-induced lung fibrosis in the mice.
Topics: Animals; CD36 Antigens; Collagen Type I; Collagen Type III; Disease Models, Animal; Female; Fibrosis | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation | 2010 |
IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Colorimetry; Cytokines; Enzyme-Linked Immunosorbent Assay; Fe | 2010 |
Altered microRNAs expression profiling in experimental silicosis rats.
Topics: Animals; Ceruloplasmin; Disease Models, Animal; Hydroxyproline; Lung; Male; Microarray Analysis; Mic | 2012 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine | 1964 |
[EXPERIMENTAL STUDY ON ELIMINATION OF DUST FROM THE LUNG. I. RELATION OF BRONCHIAL AND LUNG CHANGES TO ELIMINATION OF SILICA DUST IN RATS].
Topics: Bronchitis; Calcium; Calcium, Dietary; Dust; Hexosamines; Hydroxyproline; Lung; Mineral Waters; Rats | 1964 |
[CHANGES IN THE TOTAL LIPID CONTENT IN THE LUNG OF RATS WITH EXPERIMENTAL SILICOSIS].
Topics: Aluminum Silicates; Exudates and Transudates; Histocytochemistry; Hydroxyproline; Lipid Metabolism; | 1964 |
[HYDROXYPROLINE CONTENT OF BLOOD SERUM IN NORMAL PERSONS AND SILICOSIS PATIENTS].
Topics: Blood; Humans; Hydroxyproline; Serum; Silicosis | 1964 |
Antifibrotic effect of interferon gamma in silicosis model of rat.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Immunohistochemistry; Interferon-gamma; Int | 2005 |
Comparing study of the effect of nanosized silicon dioxide and microsized silicon dioxide on fibrogenesis in rats.
Topics: Animals; Female; Hydroxyproline; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Inhal | 2004 |
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.
Topics: Administration, Inhalation; Animals; Collagen; Cytokines; Disease Models, Animal; Hydroxyproline; In | 2006 |
Dust content of lungs and its relationships to pathology, radiology and occupational exposure in Ontario hardrock miners.
Topics: Aged; Air Pollutants, Occupational; Autopsy; Dust; Gold; Humans; Hydroxyproline; Lung; Middle Aged; | 2008 |
[Quantitative determination of oxyproline and lysine in the blood serum].
Topics: Chromatography, Thin Layer; Humans; Hydrolysis; Hydroxyproline; Liver Cirrhosis, Alcoholic; Lysine; | 1982 |
[Hydrolyzed dextran as a means of preventing silicosis].
Topics: Animals; Dextrans; Female; Hydroxyproline; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lun | 1984 |
A mathematical pattern of the evaluation of biological aggressiveness of silica dusts.
Topics: Animals; Dust; Female; Hydroxyproline; Lung; Male; Organ Size; Rats; Rats, Inbred Strains; Regressio | 1981 |
Experimental silicosis. II. Long-term effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs.
Topics: Animals; Collagen; Hydroxyproline; Hyperplasia; Hypertrophy; Lung; Organ Size; Proline; Quartz; Rats | 1983 |
Functional and morphologic changes in the lungs after a single intratracheal instillation of silica.
Topics: Animals; Dose-Response Relationship, Drug; Hydroxyproline; Lung; Male; Organ Size; Rats; Rats, Inbre | 1984 |
[Determination of total plasma hydroxyproline and its clinical application].
Topics: Adult; Female; Humans; Hydroxyproline; Male; Middle Aged; Silicosis | 1984 |
Role of polymorphonuclear leukocytes in silica-induced pulmonary fibrosis.
Topics: Animals; Autoradiography; Cell Division; Collagen; DNA; Glucuronidase; Hexosaminidases; Hydroxyproli | 1984 |
[Antisilicotic and side effects of a new drug pyracryl].
Topics: Animals; Diuresis; Hydroxyproline; Liver Function Tests; Polymethacrylic Acids; Polyvinylpyridine N- | 1983 |
Experimental silicosis. I. Acute effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Lung; Particle Size; Proline; Proteins; Quartz; Rats; | 1982 |
[Urinary hydroxyproline in experimental silicosis in rats].
Topics: Animals; Circadian Rhythm; Hydroxyproline; Male; Rats; Silicosis | 1980 |
[Effect of the age factor on lipid metabolic status and the development of silicosis in rats].
Topics: Aging; Animals; Body Weight; Hydroxyproline; Kidney; Lipid Metabolism; Lung; Male; Myocardium; Organ | 1981 |
[Effect of antioxidants on lipid metabolism and fibrogenesis disorders in lung tissue in experimental silicosis].
Topics: Animals; Antioxidants; Dietary Fats; Fatty Acids, Nonesterified; Female; Hydroxyproline; Lipid Perox | 1981 |
[Changes in the oxyproline content in the blood and urine in patients with various forms of the course of pulmonary dust diseases].
Topics: Bronchitis; Chronic Disease; Humans; Hydroxyproline; Mining; Pneumoconiosis; Siberia; Silicosis | 1980 |
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice.
Topics: Animals; Bleomycin; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pulmonar | 1994 |
[Changes of cellular hydroxyl proline and some other parameters of rats in early bronchoalveolar lavage treated with quartz dust].
Topics: Animals; Bronchoalveolar Lavage Fluid; Dust; Hydroxyproline; L-Lactate Dehydrogenase; Male; Quartz; | 1994 |
Increased susceptibility to silicosis and TNF-alpha production in C57BL/6J mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Susceptibility; Enzyme-Linked Immunosorbe | 1995 |
Role of interleukin-10 in the lung response to silica in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Female; Hydroxyproline; In | 1998 |
Quantitative image analysis of lung connective tissue in murine silicosis.
Topics: Animals; Collagen; Connective Tissue; Fluorescent Dyes; Hydroxyproline; Image Processing, Computer-A | 2000 |
Immunoglobulin responses to experimental silicosis.
Topics: Administration, Inhalation; Animals; B-Lymphocyte Subsets; Bronchoalveolar Lavage Fluid; Cells, Cult | 2001 |
[The relationship between the physical characteristic of quartz dusts and their influence on biochemical and morphological changes in rat lungs (author's transl)].
Topics: Animals; Dust; Hydroxyproline; Lipid Metabolism; Lung; Male; Particle Size; Quartz; Rats; Silicon Di | 1975 |
[Experimental silicosis. Evaluation of the silicogenic properties of apatites and phosphorites].
Topics: Animals; Apatites; Hydroxyproline; Lung; Occupational Medicine; Organ Size; Rats; Silicosis | 1978 |
[Disturbance of free-radical processes in the lungs during the development of experimental silicosis].
Topics: Animals; Carrier Proteins; Dust; Free Radicals; Hydroxyproline; Lung; Male; Rats; Silicosis; Time Fa | 1977 |
[Use of the hydroxyproline-glucuronate test in the examination of patients with various forms of dust-induced diseases].
Topics: Glucuronates; Humans; Hydroxyproline; Silicosis; Silicotuberculosis | 1977 |
[Characteristics of the changes in lipid metabolism and hydroxyproline level in the lungs of rats at different periods of development of silicosis].
Topics: Animals; Dust; Hydroxyproline; Lipid Metabolism; Lung; Quartz; Rats; Silicosis | 1977 |
[Study of urinary excretion of hydroxyproline in experimental silicosis].
Topics: Animals; Disease Models, Animal; Hydroxyproline; Male; Rats; Silicosis | 1976 |
[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].
Topics: Air Pollutants; Animals; Chemical Industry; Coke; Disease Models, Animal; Dust; Ferric Compounds; Hy | 1991 |
[Value of biochemical and immunological studies in the diagnosis of silicosis].
Topics: Acetylglucosaminidase; Adult; Alpha-Globulins; beta-Galactosidase; Ceruloplasmin; Complement C3; Com | 1991 |
[Urinary excretion of hydroxyproline after exposure to quartz dust and glutamic acid].
Topics: Animals; Circadian Rhythm; Dust; Glutamates; Glutamic Acid; Hydroxyproline; Quartz; Rats; Silicon Di | 1989 |
Fasting urinary hydroxyproline: creatinine ratios in silicosis.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Fasting; Humans; Hydroxyproline; Male; Middle Aged; Sili | 1989 |
Aluminum inhalation reduces silicosis in a sheep model.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Fibronectins; Glutathione; Hydrog | 1988 |
The influence of some detergents on the retention and elimination of silica dust from the lungs of albino rats and development of fibrous changes.
Topics: Animals; Detergents; Dust; Hydroxyproline; Lung; Male; Rats; Rats, Inbred Strains; Silicon Dioxide; | 1988 |
Sulfated glycosaminoglycans in rat lung tissue during experimental silicotic fibrosis.
Topics: Animals; Chondroitin Sulfates; Dermatan Sulfate; Glycosaminoglycans; Heparitin Sulfate; Hydroxyproli | 1987 |
The role of complement in experimental silicosis.
Topics: Animals; Complement Activation; Complement C3; Complement C5; Female; Hydroxyproline; Lung; Male; Mi | 1986 |
Formation of granulomas in liver of silica-treated rats.
Topics: Animals; Aspartic Acid Endopeptidases; beta-Galactosidase; DNA; Endopeptidases; Female; Granuloma; H | 1986 |
Treatment of experimental silicosis with antifibrotic agents.
Topics: Aminopropionitrile; Animals; Body Weight; Bone and Bones; Cricetinae; Hydroxyproline; Lung; Male; Me | 1988 |
[Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis].
Topics: Adult; Aging; Female; Humans; Hydroxyproline; Male; Middle Aged; Pulmonary Fibrosis; Radiography; Si | 1986 |
[Relation of quartz dust dose to the extent of inflammatory reaction of the lungs].
Topics: Animals; Hydroxyproline; Lung; Rats; Silicon Dioxide; Silicosis | 1965 |
Conflicting hypotheses on experimental silicotic fibrogenesis: new experimental data.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Collagen; Dust; Granuloma; Guinea Pigs; Hydroxyproline; Liv | 1967 |
Lactate dehydrogenase isoenzymes during the development of experimental fibrosis.
Topics: Animals; Buffers; Centrifugation; Collagen; Cystic Fibrosis; Electrophoresis; Hydroxyproline; Isoenz | 1970 |
Histamine metabolism in experimental silicosis. II. In vivo experiments in guinea pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Collagen; Disease Models, Animal; Guinea | 1971 |
Experimental silicosis of the rat. Correlation of functional, biochemical, and histological changes.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Hematocrit; Hemoglobinometry; Hydroxyproline; L | 1971 |
Experimental lung silicosis. Evolution of functional, biochemical, and morphological changes in the rat.
Topics: Animals; Blood Gas Analysis; Hydroxyproline; Lung; Lung Compliance; Male; Rats; Respiratory Function | 1972 |
[Content of quartz, hydroxyproline and lipids in pulmonary tissue and lymph nodes in patients with silicosis and silicotuberculosis].
Topics: Gold; Humans; Hydroxyproline; Lipid Metabolism; Lung; Lymph Nodes; Mining; Silicon Dioxide; Silicosi | 1971 |
A method for inducing unilateral silicosis in rabbits by an injection technique with some observations on lung clearance and quantitative evaluation of experimental silicosis.
Topics: Animals; Autopsy; Catheterization; Collagen; Female; Hydroxyproline; Injections; Intubation, Intratr | 1973 |
[Change in the fibrous nature of quartz dust].
Topics: Animals; Calcium Hydroxide; Dust; Hydroxyproline; Lung; Organ Size; Rats; Silicon Dioxide; Silicosis | 1973 |
The induction of fibrogenesis by silica-treated alveolar macrophages.
Topics: Animals; Cells, Cultured; Fibroblasts; Hydroxyproline; Macrophages; Methods; Pulmonary Alveoli; Rabb | 1973 |
[Changes in lipid metabolism in rats during chronic inhalation of quartz dust].
Topics: Animals; Cholesterol; Fatty Acids, Nonesterified; Hydroxyproline; Ketone Bodies; Lipid Metabolism; L | 1973 |
[Silicosis hazards in mining and concentration of tin ore].
Topics: Adult; Animals; Humans; Hydroxyproline; Lung; Male; Mining; Rats; Silicosis; Tin | 1971 |
Protocollagen proline hydroxylase activity in experimental pulmonary fibrosis of rats.
Topics: Animals; Ascorbic Acid; Collagen; Disease Models, Animal; Hydroxyproline; Iron; Ketoglutaric Acids; | 1970 |
[The effect of Freund's adjuvant on the development of experimental silicosis].
Topics: Animals; Freund's Adjuvant; Hydroxyproline; Lung; Male; Rats; Silicosis | 1968 |