Compounds > hydroxyproline
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hydroxyproline and Scleroderma, Localized

hydroxyproline has been researched along with Scleroderma, Localized in 20 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Scleroderma, Localized: A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.

Research Excerpts

ExcerptRelevanceReference
"Five cases of progressive facial hemiatrophy (PFH) are reported."1.28Progressive facial hemiatrophy: report of five cases and biochemical analysis of connective tissue. ( Nishikawa, T; Sakuraoka, K; Tajima, S, 1992)
"Hydroxylysine concentration was not changed in patients with generalized morphoea."1.27Collagen specific amino acids in skin in localized scleroderma. ( Ammitzbøll, T; Møller, R; Serup, J, 1984)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's3 (15.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozgen, M1
Koca, SS2
Dagli, AF1
Gundogdu, B1
Ustundag, B2
Isik, A2
FLEISCHMAJER, R2
Ozercan, IH1
Evren, B1
Metin, K1
Ammitzbøll, T2
Serup, J3
Møller, R1
Duterque, M1
Crouzet, J1
Kouri, N1
Brinckmann, J1
Açil, Y1
Tronnier, M1
Notbohm, H1
Bätge, B1
Schmeller, W1
Koch, MH1
Müller, PK1
Wolff, HH1
Yamamoto, T1
Takagawa, S1
Katayama, I1
Mizushima, Y1
Nishioka, K1
Blumenkrantz, N1
Asboe-Hansen, G1
Rodnan, GP1
Lipinski, E1
Luksick, J1
Fedorova, EG1
Lashmanova, AP1
Dabrowski, J1
Stachow, A1
Jabłońska, S1
Walski, M1
Bashey, RI1
Halpern, S1
Stephens, RE1
Perlish, JS1
Sakuraoka, K1
Tajima, S1
Nishikawa, T1
Kähäri, VM1
Heino, J1
Vuorio, T1
Vuorio, E1
Suchkova, TN1
Prozorovskaia, NN1
Suchkov, SV1
Del'vig, AA1
Herbert, CM1
Lindberg, KA1
Jayson, MI1
Bailey, AJ1
Uitto, J1
Keiser, HR1
Stein, HD1
Sjoerdsma, A1

Reviews

2 reviews available for hydroxyproline and Scleroderma, Localized

ArticleYear
Localized scleroderma (morphoea). Clinical, physiological, biochemical and ultrastructural studies with particular reference to quantitation of scleroderma.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 122

    Topics: Amino Acids; Blood Vessels; Cell Nucleus; Collagen; Connective Tissue; Cornea; Cytoplasm; Elasticity

1986
Collagen biosynthesis in human skin. A review with emphasis on scleroderma.
    Annals of clinical research, 1971, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Carbon Isotopes; Child; Child, Preschool; Collagen; Collagen D

1971

Other Studies

18 other studies available for hydroxyproline and Scleroderma, Localized

ArticleYear
Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma.
    Clinical and experimental dermatology, 2012, Volume: 37, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Humanized; Bleomycin; Cytokines; Dacli

2012
THE COLLAGEN IN SCLERODERMA.
    Archives of dermatology, 1964, Volume: 89

    Topics: Amino Acids; Collagen; Connective Tissue; Histocytochemistry; Humans; Hydroxyproline; Scleroderma, L

1964
Effectiveness of etanercept in bleomycin-induced experimental scleroderma.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:2

    Topics: Animals; Antirheumatic Agents; Bleomycin; Cytokines; Disease Models, Animal; Etanercept; Female; Hyd

2008
Collagen metabolites in urine in localized scleroderma (morphoea).
    Acta dermato-venereologica, 1984, Volume: 64, Issue:6

    Topics: Adolescent; Adult; Aged; Collagen; Cornea; Female; Humans; Hydroxylysine; Hydroxyproline; Male; Midd

1984
Collagen specific amino acids in skin in localized scleroderma.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Amino Acids; Collagen; Female; Humans; Hydroxylysine; Hydroxyproline; Male;

1984
[Sclerodermiform lesions in Lobstein's disease].
    Annales de dermatologie et de venereologie, 1984, Volume: 111, Issue:8

    Topics: Adult; Collagen; Diagnosis, Differential; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteoge

1984
Altered x-ray diffraction pattern is accompanied by a change in the mode of cross-link formation in lipodermatosclerosis.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:4

    Topics: Amino Acids; Biopsy; Collagen; Drug Residues; Humans; Hydroxylysine; Hydroxyproline; Leg; Reference

1996
Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:5

    Topics: Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Injections, Intravenous; Mannitol; Mice;

1999
Abnormal skin collagen in scleroderma.
    Acta dermato-venereologica, 1978, Volume: 58, Issue:1

    Topics: Collagen; Humans; Hydroxylysine; Hydroxyproline; Scleroderma, Localized; Skin

1978
Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Aged; Biopsy; Collagen; Female; Humans; Hydroxyproline; Male; Middle

1979
[Dynamics of hydroxyproline content as the indicator of the severity of the course and the effectiveness of treatment of focal scleroderma].
    Vestnik dermatologii i venerologii, 1978, Issue:12

    Topics: Adolescent; Adult; Aged; Circadian Rhythm; Female; Humans; Hydroxyproline; Male; Middle Aged; Sclero

1978
[Ultrastructural and biochemical study of collagen in scleroderma].
    Reumatologia, 1978, Volume: 16, Issue:1

    Topics: Collagen; Connective Tissue; Humans; Hydroxyproline; Scleroderma, Localized; Scleroderma, Systemic

1978
Solubility of collagen from normal and scleroderma fibroblasts in culture.
    Biochemical and biophysical research communications, 1975, Jan-20, Volume: 62, Issue:2

    Topics: Biopsy; Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxyproline; Nitriles; Proline; Propionat

1975
Progressive facial hemiatrophy: report of five cases and biochemical analysis of connective tissue.
    Dermatology (Basel, Switzerland), 1992, Volume: 185, Issue:3

    Topics: Adolescent; Adult; Dermatan Sulfate; Facial Hemiatrophy; Female; Glycosaminoglycans; Histocytochemis

1992
Interferon-alpha and interferon-gamma reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture.
    Biochimica et biophysica acta, 1988, Jan-18, Volume: 968, Issue:1

    Topics: Cells, Cultured; Collagen; Female; Fibroblasts; Humans; Hydroxyproline; Interferon Type I; Interfero

1988
[Immunocorrecting therapy in focal scleroderma].
    Vestnik dermatologii i venerologii, 1987, Issue:9

    Topics: Adjuvants, Immunologic; Adult; Aged; Chronic Disease; Collagen; Cytotoxicity, Immunologic; Drug Eval

1987
Biosynthesis and maturation of skin collagen in scleroderma, and effect of D-penicillamine.
    Lancet (London, England), 1974, Feb-09, Volume: 1, Issue:7850

    Topics: Adolescent; Adult; Age Factors; Aged; Amino Acids; Animals; Biopsy; Collagen; Culture Techniques; Fe

1974
Increased protocollagen proline hydroxylase activity in sclerodermatous skin.
    Archives of dermatology, 1971, Volume: 104, Issue:1

    Topics: Adolescent; Adult; Aged; Biopsy; Child; Collagen; Female; Humans; Hydroxyproline; Male; Middle Aged;

1971