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hydroxyproline and Schistosoma mansoni Infection

hydroxyproline has been researched along with Schistosoma mansoni Infection in 18 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Liver fibrosis is a pathological process complicating schistosomiasis."1.46Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis. ( Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM, 2017)
"Praziquantel (PZQ) is an isoquinoline derivative (2-cyclohexylcarbonyl-1, 2, 3, 6, 7, 11b-hexahydro-4H-pyrazino{2,1-a}-isoquinoline-4-one), and is currently the drug of choice for all forms of schistosomiasis."1.38Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. ( Ain-Shoka, AA; Badawy, AA; Ebeid, FA; El-Lakkany, NM; El-Maadawy, WH; Hammam, OA, 2012)
"Induction of liver fibrosis was produced in male Swiss mice by subcutaneous injection of S."1.37Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice. ( El-Agamy, DS; Said, SA; Shebl, AM, 2011)
"Schistosomiasis mansoni is a tropical helminthic disease characterized by parasite egg-induced granulomatous inflammation and cumulative fibrosis."1.32Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice. ( Boros, DL; Gerard, HC; Hudson, AP; Singh, KP, 2004)
"Treatment with ibuprofen (20 mg/kg."1.29Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium. ( Abou-Basha, L; Farag, MM; Salama, MA, 1995)
"Treatment with oxamniquine resulted in near total eradication of S."1.28Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis. ( Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1992)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (33.33)18.2507
2000's6 (33.33)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elhenawy, AA1
Ashour, RH1
Nabih, N1
Shalaby, NM1
Megahed, N1
El-Gamal, RR1
Nada, SM1
Moustafa, NE1
Afify, HA2
Fathy, GM1
Metwally, S1
Hamza, RS1
Hessien, MH1
El-Sharkawi, IM1
El-Barbary, AA1
El-Beltagy, DM1
Snyder, N1
El-Lakkany, NM2
El-Maadawy, W1
Ain-Shoka, A1
Badawy, A1
Hammam, O1
Ebeid, F2
El-Lakkany, N1
el-Din, SS1
El-Agamy, DS1
Shebl, AM1
Said, SA1
Hammam, OA1
El-Maadawy, WH1
Badawy, AA1
Ain-Shoka, AA1
Ebeid, FA1
el-Shafei, MM1
Mattar, MA1
Singh, KP2
Gerard, HC2
Hudson, AP2
Boros, DL2
White, SL1
Cutroneo, KR1
Farag, MM1
Salama, MA1
Abou-Basha, L1
Andrade, ZA1
Cox, TM1
Cheever, AM1
Adewusi, OI1
Nix, NA1
Lu, X1
Colley, DG1
Secor, WE1
Hoffmann, KF1
McCarty, TC1
Segal, DH1
Chiaramonte, M1
Hesse, M1
Davis, EM1
Cheever, AW1
Meltzer, PS1
Morse, HC1
Wynn, TA1
Potter, JJ1
Mezey, E1
Morcos, SH1
Mansour, MM1
Khayyal, MT1
Saleh, S1
Ishak, EA1
Girgis, NI1
Nawar, O1
Akridge, RE1
Hassan, E1
el Gazar, R1
Doughty, BL1
Kemp, WM1
Van Gool, J1
Van Tiel, D1
Doenhoff, MJ1
Van Vugt, H1

Other Studies

18 other studies available for hydroxyproline and Schistosoma mansoni Infection

ArticleYear
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
    Parasitology international, 2017, Volume: 66, Issue:5

    Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedge

2017
Relationship between serum cytokines profiles and hepatic fibrosis in schistosomiasis mansoni: an experimental study.
    Journal of the Egyptian Society of Parasitology, 2009, Volume: 39, Issue:3

    Topics: Animals; Cytokines; Hydroxyproline; Interferon-gamma; Interleukin-4; Liver Cirrhosis, Experimental;

2009
Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and Schistosomal infection in mice.
    BMC gastroenterology, 2010, Jun-01, Volume: 10

    Topics: Animals; Bilirubin; Biomarkers; Biopsy; Collagen; Disease Models, Animal; Ethanol; gamma-Glutamyltra

2010
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap

2011
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
    Experimental parasitology, 2011, Volume: 129, Issue:2

    Topics: Animals; Collagen; Cytokines; Down-Regulation; Drug Therapy, Combination; Free Radical Scavengers; H

2011
Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice.
    Inflammopharmacology, 2011, Volume: 19, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Bilirubin; Curcumin; Hydroxy

2011
Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis.
    Parasites & vectors, 2012, Jan-11, Volume: 5

    Topics: Animals; Drug Therapy, Combination; Hydroxyproline; Liver; Liver Cirrhosis; Liver Function Tests; Ma

2012
Parasitological and immunological changes in murine hepatic schistosomiasis before and after praziquantel treatment.
    Journal of the Egyptian Society of Parasitology, 2002, Volume: 32, Issue:2

    Topics: Animals; Anthelmintics; Feces; Hydroxyproline; Intestines; Liver; Liver Diseases, Parasitic; Mice; P

2002
Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice.
    Immunology, 2004, Volume: 111, Issue:3

    Topics: Animals; Anthelmintics; Body Weight; Cell Count; Cells, Cultured; Collagen; Cytokines; Female; Gene

2004
A novel nonsteroidal antifibrotic oligo decoy containing the TGF-beta element found in the COL1A1 gene which regulates murine schistosomiasis liver fibrosis.
    Journal of cellular physiology, 2005, Volume: 204, Issue:2

    Topics: Animals; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Consensus Sequence; DNA; Female;

2005
Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium.
    Annals of tropical medicine and parasitology, 1995, Volume: 89, Issue:5

    Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Feces; gamma-Glutamyltransferase; Hydroxyproline; Ib

1995
Regression of hepatic lesions after treatment of Schistosoma mansoni or Schistosoma japonicum infection in mice: a comparative study.
    The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:1

    Topics: Animals; Collagen; Granuloma; Hydroxyproline; Liver; Lung; Mice; Praziquantel; Schistosoma japonicum

1993
Schistosoma mansoni: relationship of tumor necrosis factor-alpha to morbidity and collagen deposition in chronic experimental infection.
    Experimental parasitology, 1996, Volume: 84, Issue:2

    Topics: Acute Disease; Animals; Blotting, Northern; Chronic Disease; Collagen; Hematocrit; Hydroxyproline; L

1996
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:13

    Topics: Animals; Apoptosis; Eosinophils; Fibrosis; Gene Expression Profiling; Genotype; Hydroxyproline; Infl

2001
Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni.
    Liver, 2002, Volume: 22, Issue:2

    Topics: Animals; Collagen; Disease Models, Animal; Granuloma; Hydroxyproline; Immunohistochemistry; Leptin;

2002
Evaluation of hepatic fibrosis after oxamniquine therapy of murine schistosomiasis.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:5

    Topics: Animals; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Oxamniquine; Parasite Egg Count; Schist

1992
The effect of zinc deficiency on granuloma formation, liver fibrosis, and antibody responses in experimental schistosomiasis.
    The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:3

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Collagen; Granuloma; Helminth Proteins; Hydroxypr

1992
Effect of acute phase proteins, especially alpha 2-macroglobulin, on granuloma formation around Schistosoma mansoni eggs in the rat.
    Parasitology, 1991, Volume: 102 Pt 1

    Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Collagen; Granuloma; Host-Parasite Interactions

1991