hydroxyproline has been researched along with Oxaluria, Primary in 10 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The major clinical manifestation of the Primary Hyperoxalurias (PH) is increased production of oxalate, as a consequence of genetic mutations that lead to aberrant glyoxylate and hydroxyproline metabolism." | 1.56 | The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria. ( Buchalski, B; Challa, A; Fargue, S; Holmes, RP; Knight, J; Lowther, WT; Wood, KD, 2020) |
| "The primary hyperoxalurias are diseases of overproduction of oxalate." | 1.33 | 4-Hydroxyproline metabolism and glyoxylate production: A target for substrate depletion in primary hyperoxaluria? ( Coulter-Mackie, MB, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belostotsky, R | 2 |
| Frishberg, Y | 2 |
| Buchalski, B | 2 |
| Wood, KD | 1 |
| Challa, A | 1 |
| Fargue, S | 2 |
| Holmes, RP | 5 |
| Lowther, WT | 4 |
| Knight, J | 4 |
| Assimos, DG | 1 |
| Siener, R | 1 |
| Hoppe, B | 1 |
| Löhr, P | 1 |
| Müller, SC | 1 |
| Latz, S | 1 |
| Summitt, CB | 1 |
| Johnson, LC | 2 |
| Jönsson, TJ | 1 |
| Parsonage, D | 1 |
| Li, X | 1 |
| Guan, Z | 1 |
| Inscho, EW | 1 |
| Liebow, A | 1 |
| Fitzgerald, K | 1 |
| Querbes, W | 1 |
| Todd Lowther, W | 1 |
| Seboun, E | 1 |
| Idelson, GH | 1 |
| Milliner, DS | 2 |
| Becker-Cohen, R | 1 |
| Rinat, C | 1 |
| Monico, CG | 1 |
| Feinstein, S | 1 |
| Ben-Shalom, E | 1 |
| Magen, D | 1 |
| Weissman, I | 1 |
| Charon, C | 1 |
| Riedel, TJ | 2 |
| Hantgan, RR | 1 |
| Murray, MS | 1 |
| Coulter-Mackie, MB | 1 |
1 review available for hydroxyproline and Oxaluria, Primary
| Article | Year |
|---|---|
Catabolism of Hydroxyproline in Vertebrates: Physiology, Evolution, Genetic Diseases and New siRNA Approach for Treatment.
Topics: Animals; Evolution, Molecular; Genetic Predisposition to Disease; Glyoxylates; Humans; Hydrogen Pero | 2022 |
9 other studies available for hydroxyproline and Oxaluria, Primary
| Article | Year |
|---|---|
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Disease Models, Animal; Female; Glycolates; Hu | 2020 |
Re: The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria.
Topics: Animals; Glycolates; Hydroxyproline; Hyperoxaluria; Hyperoxaluria, Primary; Mice; Oxalates; Oxidored | 2020 |
Metabolic profile and impact of diet in patients with primary hyperoxaluria.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Calcium; Child; Creatinine; Diet; Diet Records; Humans; | 2018 |
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria.
Topics: Biocatalysis; Catalytic Domain; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Flavoproteins; Furan | 2015 |
Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Disease Models, Animal; Hydroxyproline; Hyperoxaluria, Primary; Li | 2016 |
Mutations in DHDPSL are responsible for primary hyperoxaluria type III.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Child; Child, Preschool; DNA Mutational Analysis; Famil | 2010 |
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria.
Topics: Amino Acid Sequence; Animals; Apoenzymes; Bacteria; Catalytic Domain; Cattle; Crystallography, X-Ray | 2011 |
4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibition.
Topics: Alcohol Oxidoreductases; Animals; Cells, Cultured; CHO Cells; Cricetinae; Glutarates; Humans; Hydrox | 2012 |
4-Hydroxyproline metabolism and glyoxylate production: A target for substrate depletion in primary hyperoxaluria?
Topics: Adult; Female; Glyoxylates; Humans; Hydroxyproline; Hyperoxaluria, Primary; Male; Oxalates | 2006 |