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hydroxyproline and Osteoporosis, Postmenopausal

hydroxyproline has been researched along with Osteoporosis, Postmenopausal in 135 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Osteoporosis, Postmenopausal: Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.

Research Excerpts

ExcerptRelevanceReference
"Medical 'oophorectomy' by GnRH agonist or danazol is an effective treatment for endometriosis."9.06Evidence of similar increases in bone turnover during nafarelin and danazol use in women with endometriosis. ( Hirvonen, E; Nilsson, CG; Viinikka, L; Ylikorkala, O, 1990)
"Medical 'oophorectomy' by GnRH agonist or danazol is an effective treatment for endometriosis."5.06Evidence of similar increases in bone turnover during nafarelin and danazol use in women with endometriosis. ( Hirvonen, E; Nilsson, CG; Viinikka, L; Ylikorkala, O, 1990)
"Bone metabolism markers (bone alkaline phosphatase, ionized calcium, inorganic phosphorus, serum osteocalcin) and urinary excretion of hydroxyproline, Ca2+ and P after overnight fasting and of creatinine were studied in 52 female patients with endemic goiter and hypothyrosis (18 of these with decompensated hypothyrosis, 34 treated with thyroid hormones) and 48 women without thyroid diseases aged 45-60 years with menopause of no longer than 10 years (6."3.71[Calcium-phosphorus metabolism and bone metabolism in postmenopausal patients with the thyroid gland pathology]. ( Esedova, AE; Ferzilaeva, RA; Gadzhieva, MM, 2002)
" Alpha, body weight, and serum albumin were all significantly lower in the osteoporotic than in the normal women, and plasma alkaline phosphatase, fasting urinary calcium, sodium, and hydroxyproline were all significantly higher in the osteoporotic than in the normal group."3.68Calcium absorption in normal and osteoporotic postmenopausal women. ( Horowitz, M; Morris, HA; Need, AG; Nordin, BE; O'Loughlin, PD, 1991)
"The laboratory methods for urinary bone resorption markers were enzyme immunoassays (EIA) for urinary pyridoline (PYD) and deoxypyridoline crosslinks (DPD), and for cross-linked N-telopeptides of Type I Collagen (NTx), and an HPLC assay for urinary hydroxyproline (HOP)."2.69Urinary bone resorption markers in monitoring treatment of symptomatic osteoporosis. ( Alhava, E; Arnala, I; Jääskeläinen, K; Kröger, H; Parviainen, MT, 1999)
"Carbocalcitonin spray administered for 12 months at a daily dosage of 80 U MRC according to five schedules has been tested on 150 normal spontaneous postmenopausal women for its influence on bone mineral density (BMD), bone metabolism and osteoarticular pain."2.68Effects of cyclic therapy with intranasal carbocalcitonin in healthy spontaneous postmenopausal women. ( Abbruzzese, AD; Bottiglioni, F; Campobasso, C; De Aloysio, D; Mauloni, M; Pansini, F; Zanotti, L, 1996)
"Calcitriol has been widely used in the management of osteoporosis, but its efficiency is a matter of controversy."2.68Comparison of calcitriol treatment with etidronate-calcitriol and calcitonin-calcitriol combinations in Turkish women with postmenopausal osteoporosis: a prospective study. ( Bayraktar, M; Gedik, O; Gürlek, A, 1997)
" The incidence of adverse reactions in ipriflavone-treated patients (14."2.68Efficacy of ipriflavone in established osteoporosis and long-term safety. ( Agnusdei, D; Bufalino, L, 1997)
" Statistical analysis examined the percent changes from baseline in bone mineral density by using an analysis of covariance with treatment as a factor and the baseline value as a covariant, by performing all-pairwise comparisons among the three estradiol groups, and by testing for a linear dose-response relationship."2.67Preventive effects of transdermal 17 beta-estradiol on osteoporotic changes after surgical menopause: a two-year placebo-controlled trial. ( Field, CS; Herrmann, RR; Judd, HL; Ory, SJ; Riggs, BL; Wahner, HW, 1993)
"Thirty-six women with postmenopausal osteoporosis (31 of them with at least one non-traumatic vertebral compression fracture) were matched pair-wise as to age, years since menopause and body mass index and randomized to receive either cyclical estrogen-progestagen replacement treatment (group 1) or the same treatment plus nandrolone decanoate (group 2)."2.67Can nandrolone add to the effect of hormonal replacement therapy in postmenopausal osteoporosis? ( Birkenhäger, JC; Birkenhäger-Frenkel, DH; Erdtsieck, RJ; Gerritsma, EJ; Kooy, PP; Luiken, GP; Mulder, P; van Kuik, C; van Veen, LC; Zeelenberg, J, 1992)
" We conclude that, given rectally, sCT is well absorbed and well tolerated and that it has a beneficial effect on calcium metabolism in moderately osteoporotic women."2.67Rectal salmon calcitonin for the treatment of postmenopausal osteoporosis. ( Christiansen, C; Dirksen, KL; Hansen, MA; Overgaard, K, 1992)
"Biochemical parameters reflecting bone resorption [urinary calcium/creatinine (Ca/Cr) and hydroxyproline/creatinine (OH/Cr)] were related to serum estrogens [estrone (E1) and estradiol (E2)] in 262 healthy women including 158 patients receiving estrogen replacement therapy (ERT) for at least 6 months, 49 eugonadal women, and 55 untreated postmenopausal women."2.67Minimal levels of serum estradiol prevent postmenopausal bone loss. ( Albert, A; Deroisy, R; Franchimont, P; Gaspard, U; Reginster, JY; Sarlet, N, 1992)
"Pain was rated daily on a 10-point scale by the same observers."2.67Analgesic effect of salmon calcitonin in osteoporotic vertebral fractures: a double-blind placebo-controlled clinical study. ( Karachalios, T; Lyritis, GP; Magiasis, B; Tsakalakos, N; Tsekoura, M; Yiatzides, A, 1991)
" The knowledge derived from this study could be adapted to the dosage schedule in long-term trials in osteoporosis."2.67Synthetic human calcitonin in postmenopausal osteoporosis: a placebo-controlled, double-blind study. ( Gärdsell, P; Johnell, O; Larsson, K; Lindh, E; Ljunghall, S; Obrant, K; Sernbo, I, 1991)
"Assessment of bone resorption can be achieved with measurement of urinary hydroxyproline, urinary excretion of the pyridinium crosslinks (Pyr and D-Pyr), and by measurement of plasma TRAP activity."2.38What do we know about biochemical bone markers? ( Delmas, PD, 1991)
"Amongst the bone resorption markers studied are: 1) Calcium/creatinine urinary quotient; 2) Tartrate resistant acid phosphatase; 3) Urinary hydroxyproline; 4) Other substance derived from collagen disruption such as hydroxylysine glycoside, piridinolinic intermolecular bridges and the enzymatic activity of proline iminopeptidase."2.38[Usefulness of bone remodelling biochemical markers in the diagnosis and follow-up of Paget's bone disease, primary hyperparathyroidism, tumor hypercalcemia, and postmenopausal osteoporosis. II. Bone resorption markers]. ( de la Piedra Gordo, C; Torres Jiménez, R, 1990)
"Twenty-eight patients with postmenopausal osteoporosis (PMO), 32 patients with postmenopausal osteopenia and 30 healthy control subjects (postmenopausal non-osteoporosis) were included in this study."1.39The relationship between fibroblast growth factor 23 and osteoporosis in postmenopausal women. ( Abali, R; Celik Guzel, E; Celik, E; Guzel, S; Guzelant, AY; Kuçukyalcin, V, 2013)
"Osteoporosis is a common disease among patients undergoing transplantation."1.30Reduction of bone mass in women after bone marrow transplantation. ( Arranz, R; Carmona, L; Carvajal, I; Castañeda, S; Díaz, A; García-Vadillo, A, 1997)
"Patients with Alzheimer's disease (AD) are at increased risk for falls and hip fractures."1.30High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease. ( Asoh, T; Oizumi, K; Sato, Y, 1998)
"The urinary excretion of bone resorption markers was tested using different assays."1.30Comparison of urinary bone resorption markers in women of 40-70 years; day-to-day and long-term variation in individual subjects. ( Gerrits, MI; Oldenhave, A; Thijssen, JH; Vecht-Hart, IM, 1998)
"There was a transient further rise in bone resorption for the 10 years following menopause."1.29The effects of menopause and age on calcitropic hormones: a cross-sectional study of 655 healthy women aged 35 to 90. ( Criddle, A; Devine, A; Dick, I; Garcia-Webb, P; Gutteridge, DH; Kerr, D; Price, RI; Prince, RL; St John, A, 1995)
"Postmenopausal osteoporosis is a major health problem."1.29Postmenopausal osteoporosis. ( Sicouri, R, 1993)
"We studied 21 women with postmenopausal osteoporosis, treated with salmon calcitonin nasal spray (100 IU/daily) and calcium (1 g/daily) for six months."1.29Treatment of postmenopausal osteoporosis with salmon calcitonin nasal spray: evaluation by bone mineral content and biochemical patterns. ( Montemagno, U; Riccio, S; Romano, L; Ronsini, S; Tolino, A, 1993)
"Alendronate 7."1.29Sustained response to intravenous alendronate in postmenopausal osteoporosis. ( Kanis, JA; Khan, S; McCloskey, EV; Vasikaran, SD, 1995)
"The diagnostic criterion for postmenopausal osteoporosis was a bone mineral density (BMD) (Hologic QDR-1000) in lumbar spine and/or femoral neck more than 2 SD below the mean value corresponding to an age- and sex-matched healthy control group."1.29New biochemical markers of bone resorption derived from collagen breakdown in the study of postmenopausal osteoporosis. ( de la Piedra, C; Diaz Diego, EM; Diaz Martin, MA; Disla, T; Guerrero, R; Rapado, A, 1996)
"The hydroxyproline data were consistent with the suggestion arising from the bone formation data that remodelling declines progressively after menopause in the controls but not in the vertebral fracture patients."1.28Bone remodelling does not decline after menopause in vertebral fracture osteoporosis. ( Bradbeer, JN; Green, JR; Hampton, L; Hesp, R; Reeve, J; Sambrook, PN; Smith, T; Wand, JS; Zanelli, JM, 1992)
"Calcitriol was an effective and safe treatment of postmenopausal osteoporosis."1.28Long-term treatment with calcitriol in postmenopausal osteoporosis. ( Caniggia, A; Lore, F; Martini, G; Nuti, R; Righi, G; Turchetti, V, 1990)

Research

Studies (135)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.22)18.7374
1990's107 (79.26)18.2507
2000's21 (15.56)29.6817
2010's4 (2.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhardwaj, P1
Rai, DV1
Garg, ML1
Celik, E1
Guzel, S1
Abali, R1
Guzelant, AY1
Celik Guzel, E1
Kuçukyalcin, V1
Husek, P1
Svagera, Z1
Vsianský, F1
Franeková, J1
Simek, P1
La Vignera, S1
Vicari, E1
Tumino, S1
Ciotta, L1
Condorelli, R1
Vicari, LO1
Calogero, AE1
Heaney, RP2
Watson, P1
Potu, BK1
Nampurath, GK1
Rao, MS1
Bhat, KM1
Chiechi, LM1
Secreto, G1
D'Amore, M1
Fanelli, M1
Venturelli, E1
Cantatore, F1
Valerio, T1
Laselva, G1
Loizzi, P1
Ohta, H1
Makita, K1
Komukai, S1
Nozawa, S1
Blümel, JE1
Castelo-Branco, C1
de la Cuadra, G1
Maciver, L1
Moreno, M1
Haya, J1
Gutteridge, DH2
Holzherr, ML1
Retallack, RW1
Price, RI2
Will, RK1
Dhaliwal, SS1
Faulkner, DL1
Stewart, GO1
Stuckey, BG1
Prince, RL2
Criddle, RA1
Drury, PJ1
Tran, L1
Bhagat, CI1
Kent, GN1
Jamrozik, K1
Efstathiadou, Z1
Koukoulis, G1
Stakias, N1
Challa, A1
Tsatsoulis, A1
Zhang, RH1
Chen, KJ1
Lu, DX1
Zhu, XF1
Ma, XC1
Kim, MS1
Lee, YS1
Mukherjee, M1
Das, AS1
Das, D1
Mukherjee, S1
Mitra, S1
Mitra, C1
Gambacciani, M4
Spinetti, A2
Taponeco, F2
Ciaponi, M3
Cima, GP1
Teti, GC1
Genazzani, AR3
Dick, I1
Devine, A1
Kerr, D1
Criddle, A1
Garcia-Webb, P1
St John, A1
Reeve, J3
Pearson, J1
Mitchell, A1
Green, J1
Nicholls, A1
Justice, J1
Hudson, E1
Klenerman, L1
García-Moreno, C1
Calvo, OM1
Herrero, S1
Martín, E1
Suquía, B1
San Román, JI1
Martín, M1
García-Talavera, JR1
Calvo, JJ1
del Pino, J1
Silsand, T1
Reine, A1
Dugal, S1
Lunde, T1
Smedsrud, B1
Seeberg, T1
Delmas, PD6
Vergnaud, P1
Arlot, ME1
Pastoureau, P1
Meunier, PJ1
Nilssen, MH1
Isaia, G2
Mussetta, M1
Di Stefano, M2
Sciolla, A1
Triolo, S1
Molinatti, GM2
Jensen, JE1
Sørensen, HA2
Kollerup, G2
Jensen, LB3
Sørensen, OH2
Falch, JA1
Reginster, JY3
Deroisy, R3
Lecart, MP1
Sarlet, N2
Zegels, B1
Jupsin, I2
de Longueville, M1
Franchimont, P3
Mück, AO1
Lippert, TH1
Elders, PJ2
Lips, P2
Netelenbos, JC2
van Ginkel, FC2
Khoe, E2
van der Vijgh, WJ1
van der Stelt, PF2
Meurmans, L1
Biquet, I1
Albert, A2
Reid, IR2
Wattie, DJ1
Evans, MC2
Gamble, GD2
Stapleton, JP1
Cornish, J1
Cappagli, B3
Maffei, S1
Manetti, P1
Piaggesi, L1
Fioretti, P1
Rozenberg, S2
Gevers, R1
Peretz, A2
Vandromme, J1
Robyn, C1
Ham, H2
Passeri, M4
Pedrazzoni, M1
Pioli, G1
Butturini, L1
Ruys, AH1
Cortenraad, MG1
Gertz, BJ2
Shao, P1
Hanson, DA1
Quan, H1
Harris, ST1
Genant, HK1
Chesnut, CH1
Eyre, DR1
Mango, D1
Ricci, S1
Manna, P1
Natili, G1
Dell'Acqua, S1
Ward, RL1
Morgan, G1
Dalley, D1
Kelly, PJ1
Stevenson, JC1
Hillard, TC1
Lees, B1
Whitcroft, SI1
Ellerington, MC1
Whitehead, MI1
Affinito, P1
Di Carlo, C1
Primizia, M1
Petrillo, G1
Napolitano, V1
Tremolaterra, F1
Nappi, C2
Sicouri, R1
Seibel, MJ1
Cosman, F1
Shen, V1
Gordon, S1
Dempster, DW1
Ratcliffe, A1
Lindsay, R1
Nordin, BE8
Need, AG7
Morris, HA8
Horowitz, M7
Hatori, M1
Hasegawa, A1
Adachi, H1
Shinozaki, A1
Hayashi, R1
Okano, H1
Mizunuma, H1
Murata, K1
Tolino, A1
Romano, L1
Ronsini, S1
Riccio, S1
Montemagno, U1
Eastell, R3
Robins, SP2
Colwell, T1
Assiri, AM1
Riggs, BL3
Russell, RG1
Field, CS1
Ory, SJ1
Wahner, HW1
Herrmann, RR1
Judd, HL1
Ames, RW1
Sharpe, SJ1
Caniggia, A2
Nuti, R2
Loré, F2
Martini, G2
Frediani, B1
Giovani, S1
Gennari, C5
Agnusdei, D5
Camporeale, A1
Herzberg, M2
Lusky, A1
Blonder, J1
Frenkel, Y1
De Aloysio, D1
Pansini, F1
Campobasso, C1
Zanotti, L1
Abbruzzese, AD1
Mauloni, M1
Bottiglioni, F1
Melis, GB1
Cagnacci, A1
Bruni, V1
Falsetti, L1
Jasonni, VM1
Polatti, F1
Volpe, A1
Vasikaran, SD1
Khan, S1
McCloskey, EV2
Kanis, JA2
Guerrero, R1
Diaz Martin, MA1
Diaz Diego, EM1
Disla, T1
Rapado, A1
de la Piedra, C1
Body, JJ1
Dumon, JC1
Hotimski, A1
Praet, JP1
Moris, M1
Bergmann, P1
Sims, NA1
Moore, RJ1
Durbridge, TC1
Gonnelli, S2
Cepollaro, C1
Montomoli, M1
Gennari, L1
Montagnani, A1
Palmieri, R1
Castañeda, S1
Carmona, L1
Carvajal, I1
Arranz, R1
Díaz, A1
García-Vadillo, A1
Adami, S2
Bufalino, L4
Cervetti, R2
Di Marco, C2
Di Munno, O2
Fantasia, L2
Isaia, GC3
Serni, U2
Vecchiet, L2
Gürlek, A1
Bayraktar, M1
Gedik, O1
Colwell, A1
Hampton, L2
Langdahl, BL1
Loft, AG1
Møller, N1
Weeke, J1
Eriksen, EF1
Mosekilde, L2
Charles, P2
Heikkinen, JE1
Selander, KS1
Laitinen, K1
Arnala, I2
Väänänen, HK1
Crepaldi, G2
Mazzuoli, GF1
Ortolani, S2
Zeni, S1
Gomez-Acotto, C1
Mautalen, C2
Khan, SA1
Vasikaran, S1
Kline, WF1
Matuszewski, BK1
Beneton, MN1
Sciberras, DG1
Holland, SD1
Orgee, J1
Coombes, GM1
Rogers, SR1
Porras, AG1
Hyldstrup, L1
Storm, T1
Hansen, TS1
Abrahamsen, B2
Henriksen, FL1
Hermann, AP2
Hørder, M1
Gram, J2
Hannon, R1
Blumsohn, A1
Naylor, K1
Mazzuoli, G2
Sato, Y1
Asoh, T1
Oizumi, K1
Gerrits, MI1
Vecht-Hart, IM1
Oldenhave, A1
Thijssen, JH1
Parviainen, MT1
Jääskeläinen, K1
Kröger, H1
Alhava, E1
Uchii, M1
Takashima, M1
Sugiyama, T1
Kosaka, N1
Benussi, C2
Shi, WB1
Zhang, H1
Du, N1
Gorai, I1
Chaki, O1
Taguchi, Y1
Nakayama, M1
Osada, H1
Suzuki, N1
Katagiri, N1
Misu, Y1
Minaguchi, H1
Aerssens, J1
Declerck, K1
Maeyaert, B1
Boonen, S1
Dequeker, J1
Recker, RR1
Davies, KM1
Dowd, RM1
Ardissone, P1
Ferrari, D1
Martina, V1
Porta, M1
Tagliabue, M1
Marc, J1
Prezelj, J1
Komel, R1
Kocijancic, A1
Acca, M1
Pisani, D1
Diacinti, D1
Scarda, A1
Scarnecchia, L1
Pacitti, MT1
D'Erasmo, E1
Minisola, S1
Bianchi, G1
Manfredi, G1
Campusano, C1
López, JM1
Campino, C1
Cárdenas, I1
Rojas, A1
Scopacasa, F1
Wishart, JM2
Ostrowska, Z2
Kos-Kudla, B2
Swietochowska, E1
Marek, B2
Kajdaniuk, D2
Górski, J1
Gnudi, S2
Lisi, L1
Fini, M1
Malavolta, N1
Schmolke, B1
Cleghorn, DB2
O'Loughlin, PD2
Schroeder, BJ1
Vestergaard, P1
Eiken, P1
Brot, C1
Kolthoff, N1
Beck Nielsen, H1
Pors Nielsen, S1
Thiébaud, D2
Bigler, JM1
Renteria, S1
Pache, T1
Welti, HJ1
Landry, M1
Burckhardt, P2
Ciesielska-Kopacz, N1
Esedova, AE1
Gadzhieva, MM1
Ferzilaeva, RA1
Birkenhäger, JC1
Erdtsieck, RJ1
Zeelenberg, J1
van Kuik, C1
van Veen, LC1
Birkenhäger-Frenkel, DH1
Luiken, GP1
Kooy, PP1
Gerritsma, EJ1
Mulder, P1
Hansen, MA4
Hassager, C1
Jensen, SB1
Christiansen, C7
Overgaard, K3
Dirksen, KL1
Bettica, P1
Moro, L1
Taylor, AK1
Talbot, J1
Singer, FR1
Baylink, DJ1
Gaspard, U1
Purdie, DW1
Hay, AW1
Everett, M1
Nakamura, T1
Nagai, Y1
Yamato, H1
Suzuki, K1
Orimo, H1
Wand, JS1
Green, JR1
Hesp, R1
Bradbeer, JN1
Sambrook, PN1
Smith, T1
Zanelli, JM1
Krakauer, JC1
Kleerekoper, M1
Riis, BJ4
Puche, RC1
Rigalli, A1
Trumper, L1
Dip, O1
Pereyra, JL1
Poudes, G1
Roberti, A1
Bocanera, R1
Tozzini, R1
Pietschmann, P2
Resch, H2
Krexner, E2
Woloszczuk, W2
Willvonseder, R2
Aloia, JF1
Vaswani, A1
Yeh, JK1
McGowan, DM1
Ross, P1
Lyritis, GP1
Tsakalakos, N1
Magiasis, B1
Karachalios, T1
Yiatzides, A1
Tsekoura, M1
Leeuwenkamp, OR1
Hackeng, WH1
Schlemmer, A2
Gineyts, E2
Riis, B1
Ljunghall, S1
Gärdsell, P1
Johnell, O1
Larsson, K1
Lindh, E1
Obrant, K1
Sernbo, I1
Schoutens, A1
Laurent, E1
Markowicz, E1
Lisart, J1
De Maertelaer, V1
Cornuz, J1
Paccaud, F1
Uebelhart, D1
Johansen, JS1
De Nichilo, D1
Fletcher, CD1
Farish, E1
Leggate, J1
Hart, DM1
Dambacher, MA1
Haas, HG1
Rüegsegger, P1
Ripamonti, C1
Bonini, AM1
Pratelli, L1
Figus, E1
de la Piedra Gordo, C1
Torres Jiménez, R1
Ylikorkala, O1
Nilsson, CG1
Hirvonen, E1
Viinikka, L1
Nielsen, VA1
Hodsman, AB1
Fraher, LJ1
Rico, H1
Cabranes, JA1
Hernandez, ER1
Pérez del Molino, J1
Escudero, G1
Hartwell, D1
Turchetti, V1
Righi, G1
Foldes, J1
Steinberg, R1
Menczel, J1
Vega, E1
Gonzalez, D1
Ghiringhelli, G1
Nardi, P1
Tsai, KS1
Ebeling, PR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bone Sparing by Calcium Salts With and Without Extra Phosphorus[NCT00074711]Phase 2241 participants (Actual)Interventional2004-08-31Completed
Randomized Control Trial of Bone Loading Exercises Versus Risedronate on Bone Health in Post-Menopausal Women[NCT02186600]Phase 3276 participants (Actual)Interventional2015-02-01Completed
A Pilot Trial of 13-cis Retinoic Acid (Isotretinoin) for the Treatment of Men With Oligoasthenoteratozoospermia[NCT02061384]Phase 220 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Urinary Hydroxyproline to Creatinine Ratio at 12 Months

(NCT00074711)
Timeframe: Measured at baseline and 12 months

Interventionmicromol/mmol (Mean)
Calcium Phosphate Treatment Group5.61
Calcium Carbonate Treatment Group6.26

Change From Baseline in Urinary N-telopeptide at 12 Months

(NCT00074711)
Timeframe: Measured at baseline and 12 months

Interventionnmol bce/mmol (Mean)
Calcium Phosphate Treatment Group16.0
Calcium Carbonate Treatment Group17.1

Bone Mineral Density (BMD) Under Treatment With an Anabolic Agent (Teriparatide).

The principle outcome measure was change in bone mineral density (BMD) under treatment with an anabolic agent (teriparatide). (NCT00074711)
Timeframe: 12 months

,
Interventiong/cm2 (Mean)
Hip Bone Mineral DensitySpine Bone Mineral Density
Calcium Carbonate Treatment Group0.014500.0607
Calcium Phosphate Treatment Group0.016800.0609

Change From Baseline in Serum Phosphorus, Serum Creatinine, Serum Calcium at 12 Months

(NCT00074711)
Timeframe: Measured at baseline and 12 months

,
Interventionmg/dl (Mean)
S PhosS CrtS Ca
Calcium Carbonate Treatment Group0.2450.0510.001
Calcium Phosphate Treatment Group0.139-0.001-0.048

Change From Baseline in Urinary Calcium to Creatinine Ratio, Urinary Phosphorus to Creatinine Ratio at 12 Months

(NCT00074711)
Timeframe: Measured at baseline and 12 months

,
Interventiong/g (Mean)
Ca to CRTPh to CRT
Calcium Carbonate Treatment Group0.011-0.053
Calcium Phosphate Treatment Group0.0210.073

Lumbar Spine and Hip BMD, Measured as Grams Per Square Centimeter.

Bone mineral density (BMD, measured by dual X-ray absorptiometry - DEXA) measured at several intervals during the study. BMD measured as grams per square centimeter (g/cm2). (NCT00074711)
Timeframe: Measured at Baseline

,
Interventiong/cm2 (Mean)
Baseline (Hip)Baseline (Spine)
Calcium Carbonate Treatment Group0.780.86
Calcium Phosphate Treatment Group0.760.88

Change in Bone Mineral Density (BMD) at the Spine (L1-L4) Based on Randomization to Control, Risedronate, or Exercise Group.

Bone mineral density is the gold standard for diagnosis of low bone mass and osteoporosis and will be measured at the spine using Dual Energy X-ray Absorptiometry (DXA). (NCT02186600)
Timeframe: Baseline,6, and 12 months

,,
Interventiong/cm^2 (Mean)
Baseline6 Months12 Months
Control0.889.8870.885
Exercise0.886.8780.885
Risedronate0.892.9070.911

Change in Bone Strength Index of the Distal Tibia Based on Randomization to Control, Risedronate, or Exercise Group.

"Change in Bone Strength Index (BSI) of the distal tibia based on randomization to Control, Risedronate, or Exercise group.~BSI (mg2/mm4) at the 4% tibial site will be measured using peripheral quantitative computed tomography (pQCT)." (NCT02186600)
Timeframe: Baseline, 6, and 12 months

,,
Interventionmg^2/mm^4 (Mean)
Baseline6 Months12 Months
Control2098.72105.892107.2
Exercise20011987.422009.2
Risedronate1993.31997.322014.2

Change in Serum Measures of Bone Resorption (Serum NTx) Based on Randomization to Control, Risedronate, or Exercise Group.

Bone turnover is the process of removing old bone (resorption by osteoclasts) and replacing it with new bone (formation by osteoblasts). Menopause results in a brief period (~5 years) of accelerated turnover with resorption far exceeding formation. In this study, resorption will be measured by Serum NTx. (NCT02186600)
Timeframe: Baseline, 6, 12 months

,,
InterventionnanoMolar Bone Collagen Equivalents/L (Mean)
Baseline6 Months12 Months
Control13.9912.1612.36
Exercise15.0313.3613.92
Risedronate14.3110.3011.42

Millions of Sperm Per Ejaculate

Millions of sperm per ejaculate in men treated with 13-cis retinoic acid (NCT02061384)
Timeframe: Up to 20-weeks

InterventionMillions of sperm per ejaculate (Median)
13-cis Retinoic Acid2.5
Calcitriol 0.25 mcg3.8

Reviews

7 reviews available for hydroxyproline and Osteoporosis, Postmenopausal

ArticleYear
Can biochemical markers tell us anything about rate of bone loss?
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1994, Volume: 219

    Topics: Alkaline Phosphatase; Biomarkers; Calcium; Creatinine; Female; Humans; Hydroxyproline; Osteoporosis,

1994
[The value of laboratory studies for diagnosis of osteoporosis].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Nov-15, Volume: 89, Issue:11

    Topics: Aged; Calcium; Clinical Laboratory Techniques; Estradiol; Estrogen Replacement Therapy; Estrone; Fem

1994
[Biological markers of bone metabolism].
    Presse medicale (Paris, France : 1983), 1993, Feb-20, Volume: 22, Issue:6

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Calcium; Female; Hu

1993
Biochemical markers of bone turnover: methodology and clinical use in osteoporosis.
    The American journal of medicine, 1991, Nov-25, Volume: 91, Issue:5B

    Topics: Aging; Alkaline Phosphatase; Biomarkers; Bone Resorption; Collagen; Female; Humans; Hydroxyproline;

1991
Biochemical markers of bone turnover in diagnosis and assessment of therapy.
    The American journal of medicine, 1991, Nov-25, Volume: 91, Issue:5B

    Topics: Alkaline Phosphatase; Biomarkers; Calcium; Creatinine; Female; Humans; Hydroxyproline; Menstruation;

1991
What do we know about biochemical bone markers?
    Bailliere's clinical obstetrics and gynaecology, 1991, Volume: 5, Issue:4

    Topics: Adult; Aged; Alkaline Phosphatase; Biomarkers; Bone Matrix; Bone Remodeling; Bone Resorption; Female

1991
[Usefulness of bone remodelling biochemical markers in the diagnosis and follow-up of Paget's bone disease, primary hyperparathyroidism, tumor hypercalcemia, and postmenopausal osteoporosis. II. Bone resorption markers].
    Anales de medicina interna (Madrid, Spain : 1984), 1990, Volume: 7, Issue:10

    Topics: Acid Phosphatase; Adult; Biomarkers; Bone Resorption; Child; Female; Follow-Up Studies; Humans; Hydr

1990

Trials

59 trials available for hydroxyproline and Osteoporosis, Postmenopausal

ArticleYear
Variability in the measured response of bone to teriparatide.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011, Volume: 22, Issue:6

    Topics: Aged; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Collagen Type I;

2011
Efficacy of a soy rich diet in preventing postmenopausal osteoporosis: the Menfis randomized trial.
    Maturitas, 2002, Aug-30, Volume: 42, Issue:4

    Topics: Adult; Biomarkers; Bone Density; Bone Remodeling; Collagen; Collagen Type I; Estrogen Replacement Th

2002
Alendronate daily, weekly in conventional tablets and weekly in enteric tablets: preliminary study on the effects in bone turnover markers and incidence of side effects.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2003, Volume: 23, Issue:3

    Topics: Administration, Oral; Adult; Alendronate; Bone Density; Collagen Type I; Drug Administration Schedul

2003
A randomized trial comparing hormone replacement therapy (HRT) and HRT plus calcitriol in the treatment of postmenopausal osteoporosis with vertebral fractures: benefit of the combination on total body and hip density.
    Calcified tissue international, 2003, Volume: 73, Issue:1

    Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Calcitriol; Drug Therapy, Combination; Estro

2003
A clinical study of Yigu capsule in treating postmenopausal osteoporosis.
    Chinese journal of integrative medicine, 2005, Volume: 11, Issue:2

    Topics: Administration, Oral; Aged; Amidohydrolases; Bone and Bones; Bone Density; Calcium; Drugs, Chinese H

2005
Prospective evaluation of calcium and estrogen administration on bone mass and metabolism after ovariectomy.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1995, Volume: 9, Issue:2

    Topics: Administration, Oral; Alkaline Phosphatase; Bone and Bones; Bone Density; Calcium; Dose-Response Rel

1995
A double-blind, placebo-controlled, dose-finding trial of intermittent nasal salmon calcitonin for prevention of postmenopausal lumbar spine bone loss.
    The American journal of medicine, 1995, Volume: 98, Issue:5

    Topics: Administration, Intranasal; Alkaline Phosphatase; Animals; Bone Density; Bone Remodeling; Calcitonin

1995
Long-term effect of calcium supplementation on bone loss in perimenopausal women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:7

    Topics: Alkaline Phosphatase; Body Mass Index; Body Weight; Bone Density; Calcium; Female; Humans; Hydroxypr

1994
A 5-year controlled randomized study of prevention of postmenopausal trabecular bone loss with nasal salmon calcitonin and calcium.
    European journal of clinical investigation, 1994, Volume: 24, Issue:8

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Bone Density; Calcitonin; Calcium; Calcium, Dietary; C

1994
Continuous therapy with pamidronate, a potent bisphosphonate, in postmenopausal osteoporosis.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:6

    Topics: Aged; Alkaline Phosphatase; Bone Density; Calcium; Diphosphonates; Double-Blind Method; Female; Huma

1994
Effects of nandrolone decanoate on bone mass in established osteoporosis.
    Maturitas, 1993, Volume: 17, Issue:3

    Topics: Alkaline Phosphatase; Anabolic Agents; Bone Density; Double-Blind Method; Female; Humans; Hydroxypro

1993
Monitoring bone resorption in early postmenopausal women by an immunoassay for cross-linked collagen peptides in urine.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:2

    Topics: Alendronate; Amino Acids; Biomarkers; Bone Density; Bone Resorption; Calcium; Diphosphonates; Enzyme

1994
Preventive treatment of cortical bone loss with salmon nasal calcitonin in early postmenopausal women.
    Minerva endocrinologica, 1993, Volume: 18, Issue:3

    Topics: Absorptiometry, Photon; Administration, Intranasal; Administration, Oral; Alkaline Phosphatase; Biom

1993
Tamoxifen reduces bone turnover and prevents lumbar spine and proximal femoral bone loss in early postmenopausal women.
    Bone and mineral, 1993, Volume: 22, Issue:2

    Topics: Absorptiometry, Photon; Administration, Oral; Bone Density; Breast Neoplasms; Female; Femur Neck; Hu

1993
Postmenopausal bone loss: does HRT always work?
    International journal of fertility and menopausal studies, 1993, Volume: 38 Suppl 2

    Topics: Administration, Cutaneous; Administration, Oral; Alkaline Phosphatase; Bone Density; Calcium; Creati

1993
A new fluoride preparation for the prevention of postmenopausal osteoporosis: calcium monofluorophosphate.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1993, Volume: 7, Issue:3

    Topics: Alkaline Phosphatase; Bone Density; Calcium; Female; Fluorides; Humans; Hydroxyproline; Middle Aged;

1993
The effects of walking at the anaerobic threshold level on vertebral bone loss in postmenopausal women.
    Calcified tissue international, 1993, Volume: 52, Issue:6

    Topics: Absorptiometry, Photon; Aged; Anaerobic Threshold; Bone Density; Exercise Therapy; Female; Humans; H

1993
Preventive effects of transdermal 17 beta-estradiol on osteoporotic changes after surgical menopause: a two-year placebo-controlled trial.
    American journal of obstetrics and gynecology, 1993, Volume: 168, Issue:1 Pt 1

    Topics: Adult; Bone Density; Calcium; Cholesterol; Dose-Response Relationship, Drug; Double-Blind Method; Es

1993
Effect of calcium supplementation on bone loss in postmenopausal women.
    The New England journal of medicine, 1993, Feb-18, Volume: 328, Issue:7

    Topics: Alkaline Phosphatase; Bone Density; Calcium; Calcium, Dietary; Female; Humans; Hydroxyproline; Middl

1993
Effect of salmon calcitonin nasal spray on bone mass in patients with high turnover osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1993, Volume: 3 Suppl 1

    Topics: Administration, Intranasal; Adult; Aerosols; Bone and Bones; Bone Density; Calcitonin; Female; Human

1993
Effects of cyclic therapy with intranasal carbocalcitonin in healthy spontaneous postmenopausal women.
    Clinical and experimental obstetrics & gynecology, 1996, Volume: 23, Issue:2

    Topics: Administration, Intranasal; Alkaline Phosphatase; Bone and Bones; Bone Density; Calcitonin; Dose-Res

1996
Treatment of post-menopausal osteoporosis with recombinant human growth hormone and salmon calcitonin: a placebo controlled study.
    Clinical endocrinology, 1997, Volume: 46, Issue:1

    Topics: Amino Acids; Analgesics; Bone Density; Calcitonin; Calcium; Drug Therapy, Combination; Female; Femur

1997
Ipriflavone prevents radial bone loss in postmenopausal women with low bone mass over 2 years.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1997, Volume: 7, Issue:2

    Topics: Aged; Bone and Bones; Bone Density; Female; Humans; Hydroxyproline; Isoflavones; Middle Aged; Osteop

1997
The response to calcitriol therapy in postmenopausal osteoporotic women is a function of initial calcium absorptive status.
    Calcified tissue international, 1997, Volume: 61, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Density; Calcitriol; Calcium; Calcium, Dietary; Cre

1997
Comparison of calcitriol treatment with etidronate-calcitriol and calcitonin-calcitriol combinations in Turkish women with postmenopausal osteoporosis: a prospective study.
    Calcified tissue international, 1997, Volume: 61, Issue:1

    Topics: Absorptiometry, Photon; Administration, Intranasal; Aged; Analysis of Variance; Biomarkers; Bone Den

1997
Biochemical markers of bone resorption compared with estimates of bone resorption from radiotracer kinetic studies in osteoporosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:1

    Topics: Aged; Biomarkers; Bone Resorption; Calcium; Chromatography, High Pressure Liquid; Cross-Linking Reag

1997
Short-term intravenous bisphosphonates in prevention of postmenopausal bone loss.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:1

    Topics: Absorptiometry, Photon; Bone Density; Calcitriol; Calcium; Clodronic Acid; Collagen; Collagen Type I

1997
Effect of chronic treatment with ipriflavone in postmenopausal women with low bone mass.
    Calcified tissue international, 1997, Volume: 61 Suppl 1

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Analysis of Variance; Biomarkers; Bone Density;

1997
Efficacy of ipriflavone in established osteoporosis and long-term safety.
    Calcified tissue international, 1997, Volume: 61 Suppl 1

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Analysis of Variance; Bone Density; Bone Remodel

1997
Elimination and biochemical responses to intravenous alendronate in postmenopausal osteoporosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:10

    Topics: Aged; Alendronate; Alkaline Phosphatase; Bone Density; Calcium; Female; Half-Life; Humans; Hydroxypr

1997
Assessment of different markers of bone resorption in postmenopausal osteoporotic women treated with pamidronate.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:6

    Topics: Aged; Amino Acids; Biomarkers; Bone Resorption; Chromatography, High Pressure Liquid; Diphosphonates

1997
Effect of ipriflavone--a synthetic derivative of natural isoflavones--on bone mass loss in the early years after menopause.
    Menopause (New York, N.Y.), 1998,Spring, Volume: 5, Issue:1

    Topics: Administration, Oral; Alkaline Phosphatase; Biomarkers; Bone Density; Calcium; Cohort Studies; Creat

1998
Urinary bone resorption markers in monitoring treatment of symptomatic osteoporosis.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 279, Issue:1-2

    Topics: Aged; Anabolic Agents; Biomarkers; Bone Resorption; Calcium; Collagen; Collagen Type I; Double-Blind

1999
Hormone replacement therapy in perimenopause: effect of a low dose oral contraceptive preparation on bone quantitative ultrasound characteristics.
    Menopause (New York, N.Y.), 1999,Spring, Volume: 6, Issue:1

    Topics: Adult; Analysis of Variance; Biomarkers; Bone Density; Contraceptives, Oral, Synthetic; Desogestrel;

1999
[Clinical biochemical observations on treatment for postmenopausal osteoporosis with gusong-II].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:7

    Topics: Bone Resorption; Calcium; Drugs, Chinese Herbal; Estradiol; Female; Follow-Up Studies; Humans; Hydro

1997
Early postmenopausal bone loss is prevented by estrogen and partially by 1alpha-OH-vitamin D3: therapeutic effects of estrogen and/or 1alpha-OH-vitamin D3.
    Calcified tissue international, 1999, Volume: 65, Issue:1

    Topics: Adult; Alkaline Phosphatase; Bone Density; Calcium; Drug Therapy, Combination; Estrogens, Conjugated

1999
The effect of modifying dietary calcium intake pattern on the circadian rhythm of bone resorption.
    Calcified tissue international, 1999, Volume: 65, Issue:1

    Topics: Aged; Aged, 80 and over; Amino Acids; Bone Resorption; Calcium; Calcium, Dietary; Circadian Rhythm;

1999
The effect of low-dose continuous estrogen and progesterone therapy with calcium and vitamin D on bone in elderly women. A randomized, controlled trial.
    Annals of internal medicine, 1999, Jun-01, Volume: 130, Issue:11

    Topics: Aged; Alkaline Phosphatase; Analysis of Variance; Biomarkers; Bone Density; Calcium; Creatinine; Die

1999
VDR genotype and response to etidronate therapy in late postmenopausal women.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 10, Issue:4

    Topics: Aged; Biomarkers; Bone Density; Calcium; Etidronic Acid; Female; Genotype; Humans; Hydroxyproline; L

1999
Annual skeletal balance and metabolic bone marker changes in healthy early postmenopausal women: results of a prospective study.
    Bone, 2000, Volume: 26, Issue:4

    Topics: Absorptiometry, Photon; Aging; Alkaline Phosphatase; Biomarkers; Bone Density; Creatinine; Estrogens

2000
[Effect of low calcitonin doses on bone remodeling in postmenopausal women with high bone turnover rate].
    Revista medica de Chile, 2000, Volume: 128, Issue:4

    Topics: Alkaline Phosphatase; Analysis of Variance; Bone Remodeling; Calcitonin; Creatinine; Double-Blind Me

2000
Inhibition of bone resorption by divided-dose calcium supplementation in early postmenopausal women.
    Calcified tissue international, 2000, Volume: 67, Issue:6

    Topics: Amino Acids; Biomarkers; Bone Resorption; Calcium; Dietary Supplements; Drug Administration Schedule

2000
An open, crossover trial of calcium-fortified milk in prevention of early postmenopausal bone loss.
    The Medical journal of Australia, 2001, Sep-03, Volume: 175, Issue:5

    Topics: Algorithms; Amino Acids; Animals; Biomarkers; Body Weight; Bone Density; Calcium; Calcium, Dietary;

2001
A 3-year study of prevention of postmenopausal bone loss: conjugated equine estrogens plus medroxyprogesterone acetate versus tibolone.
    Climacteric : the journal of the International Menopause Society, 1998, Volume: 1, Issue:3

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Animals; Bone Density; Calcium; Creatinine; Estrogen R

1998
Can nandrolone add to the effect of hormonal replacement therapy in postmenopausal osteoporosis?
    Bone and mineral, 1992, Volume: 18, Issue:3

    Topics: Aged; Alkaline Phosphatase; Bone Density; Calcium; Cholesterol; Cholesterol, HDL; Drug Therapy, Comb

1992
Rectal salmon calcitonin for the treatment of postmenopausal osteoporosis.
    Calcified tissue international, 1992, Volume: 51, Issue:3

    Topics: Administration, Rectal; Aged; Alkaline Phosphatase; Bone and Bones; Bone Density; Calcitonin; Calciu

1992
Minimal levels of serum estradiol prevent postmenopausal bone loss.
    Calcified tissue international, 1992, Volume: 51, Issue:5

    Topics: Analysis of Variance; Bone Resorption; Calcium; Creatinine; Estradiol; Estrogen Replacement Therapy;

1992
Short term effects of SHD 386L and levonorgestrel on bone and mineral metabolism in the postmenopause: a double-blind randomised placebo-controlled trial.
    Maturitas, 1992, Volume: 14, Issue:3

    Topics: Alkaline Phosphatase; Bone and Bones; Calcium; Creatinine; Double-Blind Method; Estradiol; Female; F

1992
Biochemical short-term changes produced by hormonal replacement therapy.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:11

    Topics: Bone Remodeling; Calcitonin; Calcitriol; Calcium; Calcium Carbonate; Estrogen Replacement Therapy; F

1991
Analgesic effect of salmon calcitonin in osteoporotic vertebral fractures: a double-blind placebo-controlled clinical study.
    Calcified tissue international, 1991, Volume: 49, Issue:6

    Topics: Aged; Analgesics; Calcitonin; Calcium; Double-Blind Method; Female; Humans; Hydroxyproline; Osteopor

1991
Calcium supplementation reduces vertebral bone loss in perimenopausal women: a controlled trial in 248 women between 46 and 55 years of age.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:3

    Topics: Alkaline Phosphatase; Bone and Bones; Calcium; Creatine; Dose-Response Relationship, Drug; Female; F

1991
Synthetic human calcitonin in postmenopausal osteoporosis: a placebo-controlled, double-blind study.
    Calcified tissue international, 1991, Volume: 49, Issue:1

    Topics: Aged; Aged, 80 and over; Analgesia; Bone Density; Bone Resorption; Calcitonin; Calcium; Double-Blind

1991
Effects of three different calcium preparations on urinary calcium and hydroxyproline excretion in postmenopausal osteoporotic women.
    European journal of clinical nutrition, 1991, Volume: 45, Issue:7

    Topics: Absorption; Aged; Biological Availability; Calcium Carbonate; Circadian Rhythm; Creatinine; Fasting;

1991
Evidence of similar increases in bone turnover during nafarelin and danazol use in women with endometriosis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1990, Volume: 4, Issue:4

    Topics: Alkaline Phosphatase; Analysis of Variance; Bone Density; Bone Regeneration; Calcitonin; Calcium; Da

1990
Discontinuous calcitonin treatment of established osteoporosis--effects of withdrawal of treatment.
    The American journal of medicine, 1990, Volume: 89, Issue:1

    Topics: Absorptiometry, Photon; Administration, Intranasal; Aged; Alkaline Phosphatase; Bone and Bones; Bone

1990
Biochemical responses to sequential human parathyroid hormone (1-38) and calcitonin in osteoporotic patients.
    Bone and mineral, 1990, Volume: 9, Issue:2

    Topics: Aged; Alkaline Phosphatase; Calcitonin; Calcitriol; Calcium; Calcium Radioisotopes; Cyclic AMP; Drug

1990
Effect of calcium pidolate on biochemical and hormonal parameters in involutional osteoporosis.
    Maturitas, 1990, Volume: 12, Issue:2

    Topics: Aged; Alkaline Phosphatase; Calcium; Creatinine; Female; Growth Hormone; Hormones; Humans; Hydroxypr

1990
Acute effect of the intranasal administration of salmon calcitonin in osteoporotic women.
    Bone and mineral, 1989, Volume: 7, Issue:3

    Topics: Administration, Intranasal; Aged; Calcitonin; Calcium; Creatinine; Female; Humans; Hydroxyproline; M

1989
Effects of nandrolone decanoate therapy on bone mass and calcium metabolism in women with established post-menopausal osteoporosis: a double-blind placebo-controlled study.
    Maturitas, 1989, Volume: 11, Issue:3

    Topics: Alkaline Phosphatase; Anabolic Agents; Bone Density; Calcium; Clinical Trials as Topic; Double-Blind

1989

Other Studies

69 other studies available for hydroxyproline and Osteoporosis, Postmenopausal

ArticleYear
Zinc as a nutritional approach to bone loss prevention in an ovariectomized rat model.
    Menopause (New York, N.Y.), 2013, Volume: 20, Issue:11

    Topics: Animals; Catalase; Disease Models, Animal; Female; Glutathione; Humans; Hydroxyproline; Osteoporosis

2013
The relationship between fibroblast growth factor 23 and osteoporosis in postmenopausal women.
    Minerva medica, 2013, Volume: 104, Issue:5

    Topics: Alkaline Phosphatase; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium;

2013
Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis.
    Clinical chemistry and laboratory medicine, 2008, Volume: 46, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone and Bones; Bone Resorption; Dipeptides

2008
L-thyroxin treatment and post-menopausal osteoporosis: relevance of the risk profile present in clinical history.
    Minerva ginecologica, 2008, Volume: 60, Issue:6

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Body Mass Index; Bone Density; Data Interpretation, St

2008
Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats.
    La Clinica terapeutica, 2011, Volume: 162, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Alkanes; Animals; Biomarkers; Bone Diseases, Metabolic; Bone

2011
Bone resorption versus estrogen loss following oophorectomy and menopause.
    Maturitas, 2002, Sep-30, Volume: 43, Issue:1

    Topics: Amino Acids; Biomarkers; Bone Density; Bone Resorption; Calcium; Collagen Type I; Creatinine; Estrad

2002
Apolipoprotein E polymorphism is not associated with spinal bone mineral density in peri- and postmenopausal Greek women.
    Maturitas, 2004, Jul-15, Volume: 48, Issue:3

    Topics: Adult; Aged; Alleles; Apolipoprotein E4; Apolipoproteins E; Bone Density; Bone Diseases, Metabolic;

2004
Effects of soy isoflavone and/or estrogen treatments on bone metabolism in ovariectomized rats.
    Journal of medicinal food, 2005,Winter, Volume: 8, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Body Weight; Bone and Bone

2005
Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:1

    Topics: Acid Phosphatase; Alkaline Phosphatase; Allyl Compounds; Animals; Bone Density; Calcium; Cholesterol

2006
The effects of menopause and age on calcitropic hormones: a cross-sectional study of 655 healthy women aged 35 to 90.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Bone Development; Bone Resorption; Calc

1995
Evolution of spinal bone loss and biochemical markers of bone remodeling after menopause in normal women.
    Calcified tissue international, 1995, Volume: 57, Issue:2

    Topics: Absorptiometry, Photon; Aging; Biomarkers; Bone Density; Estrogen Replacement Therapy; Female; Human

1995
Heterogeneous decrease of bone mineral density in the vertebral column of ovariectomized rats.
    Bone, 1995, Volume: 16, Issue:4 Suppl

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Analysis of Variance; Animals; Body Weight; Bone Densi

1995
Urinary concentration of a specific peptide of type I collagen of bone (CrossLaps): correlation to hydroxyproline.
    Scandinavian journal of clinical and laboratory investigation, 1995, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Collagen; Female; Humans; Hydroxyproline

1995
The anabolic effect of human PTH (1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate--is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?
    Bone, 1995, Volume: 16, Issue:6

    Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Dens

1995
Metabolic markers for the early diagnosis of postmenopausal osteoporosis.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:10

    Topics: Adult; Alkaline Phosphatase; Biomarkers; Bone Density; Calcium; Creatinine; Female; Humans; Hydroxyp

1994
Biological variation of biochemical bone markers.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1994, Volume: 219

    Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Calcium; Creatinine; Female; Genetic

1994
Bone loss in perimenopausal women: a longitudinal study.
    Maturitas, 1994, Volume: 18, Issue:3

    Topics: Adult; Bone Density; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyproline; Longit

1994
Decrease of bone mineral density during estrogen substitution therapy.
    Maturitas, 1993, Volume: 17, Issue:3

    Topics: Alkaline Phosphatase; Bone Density; Creatine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate

1993
Postmenopausal osteoporosis.
    Australian family physician, 1993, Volume: 22, Issue:6

    Topics: Alkaline Phosphatase; Body Mass Index; Bone Density; Female; Fractures, Stress; Humans; Hydroxyproli

1993
Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:7

    Topics: Acid Phosphatase; Adult; Aged; Amino Acids; Biomarkers; Bone Density; Bone Resorption; Collagen; Cro

1993
The nature and significance of the relationship between urinary sodium and urinary calcium in women.
    The Journal of nutrition, 1993, Volume: 123, Issue:9

    Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Bone Resorption; Calcium; Calcium, Dietary; Creatini

1993
Treatment of postmenopausal osteoporosis with salmon calcitonin nasal spray: evaluation by bone mineral content and biochemical patterns.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7

    Topics: Absorptiometry, Photon; Administration, Inhalation; Aerosols; Bone and Bones; Calcitonin; Calcium; F

1993
Evaluation of bone turnover in type I osteoporosis using biochemical markers specific for both bone formation and bone resorption.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1993, Volume: 3, Issue:5

    Topics: Aged; Amino Acids; Biomarkers; Bone Development; Bone Resorption; Female; Humans; Hydroxyproline; Mi

1993
Total body absorptiometry in postmenopausal osteoporosis patients treated with 1 alpha-hydroxylated vitamin D metabolites.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1993, Volume: 3 Suppl 1

    Topics: Absorptiometry, Photon; Absorption; Adult; Bone Density; Calcitriol; Calcium; Female; Humans; Hydrox

1993
The effect of estrogen replacement therapy on zinc in serum and urine.
    Obstetrics and gynecology, 1996, Volume: 87, Issue:6

    Topics: Bone Density; Creatinine; Estrogen Replacement Therapy; Female; Humans; Hydroxyproline; Magnesium; M

1996
Salmon calcitonin plus intravaginal estriol: an effective treatment for the menopause.
    Maturitas, 1996, Volume: 24, Issue:1-2

    Topics: Absorptiometry, Photon; Administration, Intranasal; Administration, Intravaginal; Alkaline Phosphata

1996
Sustained response to intravenous alendronate in postmenopausal osteoporosis.
    Bone, 1995, Volume: 17, Issue:6

    Topics: Absorptiometry, Photon; Aged; Alendronate; Alkaline Phosphatase; Biomarkers; Calcium; Female; Humans

1995
New biochemical markers of bone resorption derived from collagen breakdown in the study of postmenopausal osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1996, Volume: 6, Issue:4

    Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Calcium; Collagen;

1996
Cyclical pamidronate infusions in postmenopausal osteoporosis.
    Maturitas, 1996, Volume: 25, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Density; Bone Remodeling; Calcium; Diphosphonates; Drug Admi

1996
Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats.
    Bone, 1996, Volume: 19, Issue:5

    Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Bone Density; Bone Resorption; Cell Division; D

1996
Reduction of bone mass in women after bone marrow transplantation.
    Calcified tissue international, 1997, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Marrow Transplantation;

1997
Is skeletal responsiveness to thyroid hormone altered in primary osteoporosis or following estrogen replacement therapy?
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:1

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Alkaline Phosphatase; Amino Acids; Bone Density;

1997
The effect of olpadronate in ovariectomized thyroxine-treated rats.
    Bone, 1997, Volume: 21, Issue:4

    Topics: Alkaline Phosphatase; Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Creatinin

1997
Vitamin D receptor alleles do not predict bone mineral density or bone loss in Danish perimenopausal women.
    Bone, 1998, Volume: 22, Issue:5

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Alleles; Bone Density; Bone Development; Calcitriol; C

1998
Response of biochemical markers of bone turnover to hormone replacement therapy: impact of biological variability.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:7

    Topics: Absorptiometry, Photon; Acid Phosphatase; Age Factors; Alkaline Phosphatase; Amino Acids; Biomarkers

1998
High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease.
    Bone, 1998, Volume: 23, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Bone Density; Calcium; Calcium-Binding Proteins; Extrace

1998
Comparison of urinary bone resorption markers in women of 40-70 years; day-to-day and long-term variation in individual subjects.
    Maturitas, 1998, Nov-16, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Aged; Amino Acids; Biomarkers; Bone Resorption; Collagen; Collagen Type I; Enzym

1998
[Effect of KW-8232 on bone turnover in ovariectomized rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112, Issue:5

    Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Bone Resorption; Calcium; Disease Models,

1998
Bone metabolism in type 2 diabetes mellitus.
    Acta diabetologica, 1999, Volume: 36, Issue:1-2

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Biomarkers; Bone Density; Bone Resorption; Calcium;

1999
Longitudinal evaluation of perimenopausal femoral bone loss: effects of a low-dose oral contraceptive preparation on bone mineral density and metabolism.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2000, Volume: 11, Issue:6

    Topics: Absorptiometry, Photon; Adult; Analysis of Variance; Biomarkers; Bone Density; Contraceptives, Oral;

2000
Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Circadian Rhythm; Collagen; Coll

2001
Effect of intramuscular clodronate on bone mass and metabolism in osteoporotic women.
    International journal of tissue reactions, 2001, Volume: 23, Issue:1

    Topics: Aged; Analgesics, Non-Narcotic; Bone Density; Calcium; Clodronic Acid; Female; Femur Neck; Follow-Up

2001
[Laboratory diagnosis of osteoporosis].
    Der Orthopade, 2001, Volume: 30, Issue:7

    Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Child;

2001
Evaluation of methods for prediction of bone mineral density by clinical and biochemical variables in perimenopausal women.
    Maturitas, 2001, Dec-14, Volume: 40, Issue:3

    Topics: Alkaline Phosphatase; Biomarkers; Bone Density; Climacteric; Creatinine; Cross-Sectional Studies; Fe

2001
Dynamic pattern of IGF-I and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
    Endocrine regulations, 2002, Volume: 36, Issue:1

    Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Collagen Type I; Disease Models,

2002
[Calcium-phosphorus metabolism and bone metabolism in postmenopausal patients with the thyroid gland pathology].
    Klinicheskaia laboratornaia diagnostika, 2002, Issue:3

    Topics: Alkaline Phosphatase; Bone and Bones; Calcitonin; Calcium; Female; Goiter, Endemic; Humans; Hydroxyp

2002
Is heritability a risk factor for postmenopausal osteoporosis?
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:9

    Topics: Absorptiometry, Photon; Aged; Alkaline Phosphatase; Analysis of Variance; Bone Density; Calcium; Cre

1992
Bone-resorption markers galactosyl hydroxylysine, pyridinium crosslinks, and hydroxyproline compared.
    Clinical chemistry, 1992, Volume: 38, Issue:11

    Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Resorption; Child; Chromatography, High Pressure Liquid;

1992
Regulation of bone turnover and prevention of bone atrophy in ovariectomized beagle dogs by the administration of 24R,25(OH)2D3.
    Calcified tissue international, 1992, Volume: 50, Issue:3

    Topics: 24,25-Dihydroxyvitamin D 3; Animals; Bone and Bones; Bone Resorption; Disease Models, Animal; Dogs;

1992
Bone remodelling does not decline after menopause in vertebral fracture osteoporosis.
    Bone and mineral, 1992, Volume: 17, Issue:3

    Topics: Age Factors; Aged; Alkaline Phosphatase; Bone Remodeling; Bone Resorption; Creatinine; Female; Fract

1992
Borderline-low serum thyrotropin level is correlated with increased fasting urinary hydroxyproline excretion.
    Archives of internal medicine, 1992, Volume: 152, Issue:2

    Topics: Aged; Bone Diseases, Metabolic; Calcium; Creatinine; Fasting; Female; Humans; Hydroxyproline; Hyperp

1992
Calcium absorption in normal and osteoporotic postmenopausal women.
    Calcified tissue international, 1991, Volume: 49, Issue:4

    Topics: Absorption; Adult; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Body Weight; Bone Resorptio

1991
Estimation of bone turnover in climacteric women by the whole body retention of fluoride.
    Maturitas, 1991, Volume: 14, Issue:1

    Topics: Alkaline Phosphatase; Bone and Bones; Calcium; Climacteric; Female; Fluorides; Humans; Hydroxyprolin

1991
Decreased serum osteocalcin levels in patients with postmenopausal osteoporosis.
    Acta medica Austriaca, 1991, Volume: 18, Issue:5

    Topics: Aged; Alkaline Phosphatase; Bone Density; Bone Regeneration; Calcitonin; Calcium; Female; Fractures,

1991
Urinary excretion of pyridinoline crosslinks correlates with bone turnover measured on iliac crest biopsy in patients with vertebral osteoporosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:6

    Topics: Aged; Amino Acids; Biomarkers; Bone and Bones; Bone Regeneration; Bone Resorption; Female; Humans; H

1991
Serum triiodothyronine, bone turnover, and bone mass changes in euthyroid pre- and postmenopausal women.
    Calcified tissue international, 1991, Volume: 49, Issue:2

    Topics: Adult; Alkaline Phosphatase; Bone and Bones; Bone Density; Estradiol; Estrogens; Female; Humans; Hyd

1991
[Prevalence of risk factors for osteoporosis and distribution of calciuria and hydroxyprolinuria in an elderly population of a general practice. Results of a survey among 32 practitioners of the Vaud and Fribourg districts].
    Schweizerische medizinische Wochenschrift, 1991, Sep-21, Volume: 121, Issue:38

    Topics: Aged; Calcium; Calcium, Dietary; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteoporosis; Os

1991
Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study.
    BMJ (Clinical research ed.), 1991, Oct-19, Volume: 303, Issue:6808

    Topics: Age Factors; Alkaline Phosphatase; Bone and Bones; Bone Density; Calcium; Creatinine; Female; Fractu

1991
Effect of menopause and hormone replacement therapy on the urinary excretion of pyridinium cross-links.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:2

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Hydroxyproline; Middle

1991
Effect of salt restriction on urine hydroxyproline excretion in postmenopausal women.
    Archives of internal medicine, 1991, Volume: 151, Issue:4

    Topics: Aged; Bone Resorption; Calcium; Diet, Sodium-Restricted; Female; Humans; Hydroxyproline; Menopause;

1991
Prevention of bone loss by hormone replacement therapy is probably not due to stimulation of calcitonin secretion.
    Acta endocrinologica, 1991, Volume: 124, Issue:4

    Topics: Alkaline Phosphatase; Bone and Bones; Calcitonin; Calcium; Creatinine; Estrogen Replacement Therapy;

1991
[Pathophysiology of osteoporosis and bone density determination].
    Der Internist, 1991, Volume: 32, Issue:2

    Topics: Absorptiometry, Photon; Aged; Bone and Bones; Bone Density; Calcium; Estrogens; Female; Humans; Hydr

1991
The reproducibility of bone-related biochemical variables in post-menopausal women.
    Annals of clinical biochemistry, 1990, Volume: 27 ( Pt 6)

    Topics: Aged; Biomarkers; Calcium; Creatine; Female; Humans; Hydroxyproline; Middle Aged; Osteoporosis, Post

1990
The importance of urinary hydroxyproline and serumal osteocalcin in the evaluation of post-menopausal osteoporosis.
    Italian journal of orthopaedics and traumatology, 1990, Volume: 16, Issue:4

    Topics: Adult; Aged; Bone Density; Female; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Osteoporosis, P

1990
Comparison of vitamin D metabolism in early healthy and late osteoporotic postmenopausal women.
    Calcified tissue international, 1990, Volume: 47, Issue:6

    Topics: 24,25-Dihydroxyvitamin D 3; Absorptiometry, Photon; Adult; Aging; Alkaline Phosphatase; Bone and Bon

1990
Long-term treatment with calcitriol in postmenopausal osteoporosis.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:4 Suppl 1

    Topics: Aged; Bone Density; Calcitriol; Calcium; Female; Humans; Hydroxyproline; Kidney; Middle Aged; Osteoc

1990
Zinc excretion in osteoporotic women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Bone Density; Female; Humans; Hydroxycholecalciferols; Hydrox

1990
Effects of one-year hormone replacement therapy on peripheral bone mineral content in patients with osteoporotic spine fractures.
    Acta endocrinologica, 1990, Volume: 123, Issue:1

    Topics: Alkaline Phosphatase; Bone and Bones; Double-Blind Method; Drug Therapy, Combination; Estradiol; Est

1990
Bone responsiveness to parathyroid hormone in normal and osteoporotic postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:5

    Topics: Age Factors; Aged; Bone and Bones; Bone Density; Calcium; Female; Humans; Hydroxyproline; Infusions,

1989