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hydroxyproline and Obesity

hydroxyproline has been researched along with Obesity in 26 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"In the present study, it is investigated whether restriction of dietary vitamin B2 (VB2) can reduce hepatic GO activity and oxalate excretion in mice with hyperoxaluria induce by hydroxyproline (Hyp) or obesity."8.02Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice. ( Mawatari, K; Shimohata, T; Suyama, M; Takahashi, A; Uebanso, T, 2021)
" Although hyperleptinemia is usually a characteristic of obese subjects, the relationship with atrial fibrosis and AF is unknown."7.85Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation. ( Aoki, K; Fukui, A; Fukunaga, N; Ikebe-Ebata, Y; Kondo, H; Masaki, T; Saito, S; Shinohara, T; Takahashi, N; Teshima, Y, 2017)
"In the present study, it is investigated whether restriction of dietary vitamin B2 (VB2) can reduce hepatic GO activity and oxalate excretion in mice with hyperoxaluria induce by hydroxyproline (Hyp) or obesity."4.02Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice. ( Mawatari, K; Shimohata, T; Suyama, M; Takahashi, A; Uebanso, T, 2021)
" Although hyperleptinemia is usually a characteristic of obese subjects, the relationship with atrial fibrosis and AF is unknown."3.85Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation. ( Aoki, K; Fukui, A; Fukunaga, N; Ikebe-Ebata, Y; Kondo, H; Masaki, T; Saito, S; Shinohara, T; Takahashi, N; Teshima, Y, 2017)
" In the present study the influence of a four-week daily oral administration of 2 mg/kg body weight ciprofibrate (CAS 52214-84-3) or of 100 mg/kg body weight clofibric acid (CAS 882-09-7) was compared to that of the respective doses of their newly synthesized glycine conjugates in adult male lean and obese Zucker rats."3.74Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats. ( Deufel, T; Fleck, C; Karge, E; Lupp, A; Oelschlägers, H, 2008)
"The degree of bone mineralization, estimated as the bone phosphorus/hydroxyproline ratio (P/Hypro), was studied in 33 patients who had undergone jejunoileal bypass surgery for massive obesity."3.66Elevated bone phosphorus/hydroxyproline ratio following jejunoileal bypass surgery. ( Hey, H; Tougaard, L, 1980)
"Severe energy restriction in the treatment of obesity is limited by catabolism of body protein stores and, consequently, loss of lean as well as fat tissue."2.69Metabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women. ( Berselli, ME; Cavagnini, F; Dubini, A; Montesano, A; Ortolani, S; Pincelli, AI; Scacchi, M; Silvestri, P; Tagliaferri, M, 1998)
"Obesity is associated with changes in adipose tissue extracellular matrix (ECM), but the impact of these changes on adipose tissue mechanics and their role in metabolic disease is poorly defined."1.56Elucidating nanoscale mechanical properties of diabetic human adipose tissue using atomic force microscopy. ( Baker, NA; Flesher, CG; Green, PF; Lumeng, CN; Muhammad, LN; Neeley, CK; O'Rourke, RW; Varban, OA; Wenderott, JK; Yeh, C, 2020)
"Hydroxyproline content was higher in obese animals."1.36Obesity affects collagen fibril diameter and mechanical properties of tendons in Zucker rats. ( Biancalana, A; Gomes, L; Veloso, LA, 2010)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199015 (57.69)18.7374
1990's2 (7.69)18.2507
2000's2 (7.69)29.6817
2010's4 (15.38)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Wenderott, JK1
Flesher, CG1
Baker, NA1
Neeley, CK1
Varban, OA1
Lumeng, CN1
Muhammad, LN1
Yeh, C1
Green, PF1
O'Rourke, RW1
Uebanso, T1
Suyama, M1
Shimohata, T1
Mawatari, K1
Takahashi, A1
Potnuri, AG1
Reddy, KP1
Suresh, P1
Husain, GM1
Kazmi, MH1
Harishankar, N1
Alba, DL1
Farooq, JA1
Lin, MYC1
Schafer, AL1
Shepherd, J1
Koliwad, SK1
Song, Q1
Sergeev, IN1
Fukui, A1
Ikebe-Ebata, Y1
Kondo, H1
Saito, S1
Aoki, K1
Fukunaga, N1
Shinohara, T1
Masaki, T1
Teshima, Y1
Takahashi, N1
Lupp, A1
Karge, E1
Deufel, T1
Oelschlägers, H1
Fleck, C1
Biancalana, A1
Veloso, LA1
Gomes, L1
Berria, R1
Wang, L1
Richardson, DK1
Finlayson, J1
Belfort, R1
Pratipanawatr, T1
De Filippis, EA1
Kashyap, S1
Mandarino, LJ1
Hey, H1
Tougaard, L1
Tagliaferri, M1
Scacchi, M1
Pincelli, AI1
Berselli, ME1
Silvestri, P1
Montesano, A1
Ortolani, S1
Dubini, A1
Cavagnini, F1
Gossain, VV1
Rao, DS1
Carella, MJ1
Divine, G1
Rovner, DR1
Doury, P1
Delahaye, RP1
Leguay, G1
Pattin, S1
Metges, PJ1
Montely, JM1
Duret, JC1
Salhi, A1
Zamboni, G1
Soffiati, M1
Giavarina, D1
Tató, L1
Davie, MW1
Abraham, RR1
Hewins, B1
Wynn, V1
Winkler, G1
Burkhardt, H1
Rommel, K1
Goncerzewicz, M1
Socha, J1
Cichy, W1
Nagadowska, J1
Dettwiler, W1
Zender, R1
Ball, MF1
Canary, JJ1
Houck, JC1
Rakow, L1
Beneke, G1
Vogt, C1
Frommhold, W1
Bublitz, G1
Litvak, J1
Wortsman, J1
Pumarino, H1
Armendaris, R1
Brown, H1
Milner, A1
Kennedy, J1
Delena, S1
Smith, R1
Dolecek, R1
Emmrich, R1
Spencker, FB1

Trials

3 trials available for hydroxyproline and Obesity

ArticleYear
Metabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1998, Volume: 22, Issue:9

    Topics: Adult; Alkaline Phosphatase; Body Composition; Diet, Reducing; Energy Intake; Energy Metabolism; Fem

1998
Bone mineral density (BMD) in obesity effect of weight loss.
    Journal of medicine, 1999, Volume: 30, Issue:5-6

    Topics: Body Weight; Bone Density; Creatinine; Diet; Female; Humans; Hydroxyproline; Middle Aged; Obesity; W

1999
Changes in bone and muscle constituents during dieting for obesity.
    Clinical science (London, England : 1979), 1986, Volume: 70, Issue:3

    Topics: Adolescent; Adult; Bone and Bones; Calcium; Diet, Reducing; Dietary Carbohydrates; Female; Humans; H

1986

Other Studies

23 other studies available for hydroxyproline and Obesity

ArticleYear
Elucidating nanoscale mechanical properties of diabetic human adipose tissue using atomic force microscopy.
    Scientific reports, 2020, 11-24, Volume: 10, Issue:1

    Topics: Adult; Biomechanical Phenomena; Diabetes Mellitus, Type 2; Elastic Modulus; Extracellular Matrix; Fe

2020
Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:15

    Topics: Alcohol Oxidoreductases; Animals; Creatinine; Diet; Hydroxyproline; Hyperoxaluria; Kidney; Male; Mic

2021
Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:10

    Topics: Adiposity; Animals; Antipsychotic Agents; Cardiomegaly; Disease Models, Animal; Female; Haloperidol;

2021
Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans.
    The Journal of clinical endocrinology and metabolism, 2018, 09-01, Volume: 103, Issue:9

    Topics: Adiposity; Adult; Aged; Anthropometry; Asian; Blood Glucose; Body Composition; Body Mass Index; Fema

2018
High vitamin D and calcium intakes increase bone mineral (Ca and P) content in high-fat diet-induced obese mice.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:2

    Topics: Animals; Bone and Bones; Calcium; Calcium, Dietary; Cholecalciferol; Diet, High-Fat; Disease Models,

2015
Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation.
    Journal of cardiovascular electrophysiology, 2017, Volume: 28, Issue:6

    Topics: Actins; Animals; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Chemokine CCL2; Collag

2017
Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:5

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Clofibric Acid; Cytochrome P-450 Enzym

2008
Obesity affects collagen fibril diameter and mechanical properties of tendons in Zucker rats.
    Connective tissue research, 2010, Volume: 51, Issue:3

    Topics: Animals; Collagen; Extracellular Matrix; Forelimb; Hydroxyproline; Immunoenzyme Techniques; Male; Ob

2010
Increased collagen content in insulin-resistant skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:3

    Topics: Adult; Biopsy; Collagen Type I; Collagen Type III; Diabetes Mellitus, Type 2; Extracellular Matrix;

2006
Elevated bone phosphorus/hydroxyproline ratio following jejunoileal bypass surgery.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:4

    Topics: Adult; Bone and Bones; Humans; Hydroxyproline; Ileum; Jejunum; Middle Aged; Obesity; Osteomalacia; P

1980
[Diffuse articular chondrocalcinosis and Paget's disease].
    Revue du rhumatisme et des maladies osteo-articulaires, 1975, Volume: 42, Issue:10

    Topics: Adult; Aged; Alkaline Phosphatase; Chondrocalcinosis; Diabetes Complications; Female; Humans; Hydrox

1975
Mineral metabolism in obese children.
    Acta paediatrica Scandinavica, 1988, Volume: 77, Issue:5

    Topics: Alkaline Phosphatase; Blood Glucose; Bone and Bones; Calcifediol; Calcitonin; Calcitriol; Calcium; C

1988
Phasic pattern of 17-ketosteroid- and hydroxyproline-excretion in urine of man after a single ACTH administration.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1969, Volume: 1, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Collagen; Diabetes Mellitus; Female; Humans; Hydroxyproline; Ket

1969
[Hydroxyproline indicators in the evaluation of nutritional status of children with various metabolic diseases].
    Pediatria polska, 1974, Volume: 49, Issue:2

    Topics: Child; Child Nutrition Disorders; Diabetes Mellitus, Type 1; Endocrine System Diseases; Female; Huma

1974
[Collagen catabolism in reducing cures].
    Helvetica medica acta, 1972, Volume: 36, Issue:2

    Topics: Adult; Calcium; Collagen; Diet, Reducing; Female; Humans; Hydroxyproline; Middle Aged; Obesity

1972
Studies of the hydroxyprolinuria of fasting.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Bone and Bones; Calcium; Collagen; Diet; Fasting; Female; Gluconeogenesis; Growth

1972
[Changes in collagen content of white adipose tissue in starved-refed and obese mice].
    Beitrage zur Pathologie, 1971, Volume: 144, Issue:4

    Topics: Adipose Tissue; Animals; Body Weight; Cell Count; Collagen; Connective Tissue Cells; Epididymis; Hyd

1971
[Studies on subcutaneous fibroses following cobalt teletherapy and their treatment possibilities with dimethyl sulfoxide (DMSO)].
    Strahlentherapie, 1967, Volume: 133, Issue:4

    Topics: Cobalt Isotopes; Collagen; Connective Tissue; Dimethyl Sulfoxide; Female; Genital Neoplasms, Female;

1967
Effect of fasting on urinary calcium and hydroxyproline excretion in obesity.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Bone and Bones; Calcium; Collagen; Fasting; Female; Humans; Hydroxyproline; Obesi

1968
Hydroxyproline excretion during starvation of obese subjects.
    Metabolism: clinical and experimental, 1968, Volume: 17, Issue:4

    Topics: Adult; Bone and Bones; Calcium; Calorimetry; Collagen; Creatinine; Diet Therapy; Fats; Female; Growt

1968
Total hydroxyproline excretion during prolonged starvation for obesity.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:3

    Topics: Female; Humans; Hydroxyproline; Middle Aged; Nitrogen; Obesity; Potassium; Starvation

1968
[Are thyroid gland preparations indicated in the treatment of obesity?].
    Vnitrni lekarstvi, 1968, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Appetite Depressants; Diet, Reducing; Electrocardiography;

1968
[On the behavior of the so-called easily bound hydroxyproline in human skin].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, May-01, Volume: 21, Issue:9

    Topics: Aged; Arteriosclerosis; Female; Humans; Hydroxyproline; Male; Middle Aged; Neoplasm Metastasis; Obes

1966