hydroxyproline has been researched along with Necrosis in 41 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was carried out to evaluate whether curcumin, a potent antioxidant, had any specific role in the synthesis and degradation of collagen in rat heart with myocardial necrosis, induced by isoproterenol." | 7.70 | Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. ( Anand, S; Nirmala, C; Puvanakrishnan, R, 1999) |
| " Urothelial degeneration, necrosis, ulcer, bleeding, edema, inflammation and mast cell count, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), myeloperoxidase (MPO), and hydroxyproline parameters were evaluated." | 4.31 | Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model. ( Abdullah, A; Çiğdem, Y; Erhan, A; Tuğrul, EE, 2023) |
| " Pathohistological changes in pancreas, bile duct and liver as well as pathobiochemical parameters of pancreatitis (amylase and lipase activity), liver lesions (alkaline phosphatase activity and bilirubin) and fibrosis (hydroxyproline and hyaluronic acid) were measured 1 day and 1 to 24 weeks after DBTC- and DBTC/ethanol administration." | 3.70 | The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats. ( Hennighausen, G; Jonas, L; Merkord, J; Nizze, H; Weber, H, 1998) |
| "This study was carried out to evaluate whether curcumin, a potent antioxidant, had any specific role in the synthesis and degradation of collagen in rat heart with myocardial necrosis, induced by isoproterenol." | 3.70 | Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. ( Anand, S; Nirmala, C; Puvanakrishnan, R, 1999) |
| " To elucidate the mechanism for this mortality, plasma aspartate aminotransferase, retention of intravenous injected rose bengal, liver weight and liver hydroxyproline content were measured 0 to 90 days after 15 Gy irradiation of the liver to determine temporal changes in necrosis, function, mass and fibrosis, respectively, in animals with either intact livers or livers with subtotal resection." | 3.69 | Radiation hepatology of the rat: the effects of the proliferation stimulus induced by subtotal hepatectomy. ( Geraci, JP; Mariano, MS, 1994) |
| "To assess whether the reduction in ischaemic injury during acute myocardial infarction induced by nitroglycerin (NTG) results in a decrease in tissue necrosis, 96 rats were assigned to two groups." | 3.67 | Long-term protection of ischaemic myocardium by nitroglycerin ointment. ( Ambrosio, G; Brevetti, G; Cataffo, A; Chiariello, M; Condorelli, M; Pollice, U, 1984) |
| "Cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta." | 3.66 | The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. ( Cameron, AJ; Revis, NW, 1978) |
| "However, the effects of WHP on liver fibrosis remain unknown." | 1.40 | Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats. ( Endo, K; Hori, T; Iwaisako, K; Jobara, K; Kaido, T; Uchida, Y; Uemoto, S, 2014) |
| "Coffee exerts protective effects against liver fibrosis via antioxidant action and the suppression of fibrogenic cytokines, TGF-beta and PDGF-beta." | 1.36 | Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats. ( Kang, JK; Shin, JW; Son, CG; Wang, JH, 2010) |
| "The hydroxyproline content was significantly higher in the control groups than in the DMN+LSKL group." | 1.32 | A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo. ( Etani, Y; Kondou, H; Michigami, T; Miyoshi, Y; Mushiake, S; Ozono, K, 2003) |
| "Recovery from necrotising acute pancreatitis in this model is not associated with the development of chronic pancreatitis." | 1.29 | Biochemical and morphological changes that characterise recovery from necrotising biliary pancreatitis in the opossum. ( Gerdes, D; Kaiser, A; Rünzi, M; Saluja, A; Sengupta, A; Steer, ML, 1995) |
| "8 times the normal level by the fourth day after the dosing but normalized within 14 days." | 1.27 | Collagen accumulation can continue with decreased prolyl hydroxylase activity in the liver. ( Fujiwara, K; Ogata, I, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (43.90) | 18.7374 |
| 1990's | 10 (24.39) | 18.2507 |
| 2000's | 5 (12.20) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 2 (4.88) | 2.80 |
| Authors | Studies |
|---|---|
| Abdullah, A | 2 |
| Çiğdem, Y | 2 |
| Tuğrul, EE | 2 |
| Erhan, A | 2 |
| Kayapınar, AK | 1 |
| Ercan, M | 1 |
| Baş, KK | 1 |
| Yamak, S | 1 |
| Erçin, U | 1 |
| Türkoğlu, MA | 1 |
| Bostancı, EB | 1 |
| Sadeghi, H | 2 |
| Azarmehr, N | 1 |
| Razmkhah, F | 1 |
| Danaei, N | 1 |
| Omidifar, N | 1 |
| Vakilpour, H | 1 |
| Pourghadamyari, H | 1 |
| Doustimotlagh, AH | 1 |
| Dong, W | 1 |
| Lv, B | 1 |
| Wei, F | 1 |
| Yang, L | 1 |
| Jobara, K | 1 |
| Kaido, T | 1 |
| Hori, T | 1 |
| Iwaisako, K | 1 |
| Endo, K | 1 |
| Uchida, Y | 1 |
| Uemoto, S | 1 |
| Zhan, YY | 1 |
| Wang, JH | 2 |
| Tian, X | 1 |
| Feng, SX | 1 |
| Xue, L | 1 |
| Tian, LP | 1 |
| Dinulovic, I | 1 |
| Furrer, R | 1 |
| Di Fulvio, S | 1 |
| Ferry, A | 1 |
| Beer, M | 1 |
| Handschin, C | 1 |
| Shin, JW | 1 |
| Kang, JK | 1 |
| Son, CG | 1 |
| GOLDSTEIN, ER | 1 |
| PATEL, YM | 1 |
| HOUCK, JC | 2 |
| Kondou, H | 1 |
| Mushiake, S | 1 |
| Etani, Y | 1 |
| Miyoshi, Y | 1 |
| Michigami, T | 1 |
| Ozono, K | 1 |
| Zadorozhnyi, AV | 1 |
| Popkov, VL | 1 |
| Galenko-Yaroshevskii, VP | 1 |
| Antelava, AV | 1 |
| Chikobava, EA | 1 |
| Sukoyan, GV | 1 |
| Meladze, VN | 1 |
| Xu, D | 1 |
| Wu, Y | 1 |
| Liao, ZX | 1 |
| Wang, H | 1 |
| Chiariello, M | 1 |
| Brevetti, G | 1 |
| Ambrosio, G | 1 |
| Cataffo, A | 1 |
| Pollice, U | 1 |
| Condorelli, M | 1 |
| Jacobs, TP | 1 |
| Siris, ES | 1 |
| Bilezikian, JP | 1 |
| Baquiran, DC | 1 |
| Shane, E | 1 |
| Canfield, RE | 1 |
| Hottenrott, C | 1 |
| Silber, R | 1 |
| Hauk, H | 1 |
| Weigand, H | 1 |
| Rünzi, M | 1 |
| Saluja, A | 1 |
| Kaiser, A | 1 |
| Gerdes, D | 1 |
| Sengupta, A | 1 |
| Steer, ML | 1 |
| Yamaner, S | 1 |
| Buğra, D | 1 |
| Müslümanoğlu, M | 1 |
| Bulut, T | 1 |
| Cubukçu, O | 1 |
| Ademoğlu, E | 1 |
| Geraci, JP | 1 |
| Mariano, MS | 1 |
| Hoshi, K | 1 |
| Honda, S | 1 |
| Endo, C | 1 |
| Sato, A | 1 |
| Sekimoto, S | 1 |
| Goldberg, I | 1 |
| Knight, KR | 1 |
| Mahoney, JE | 1 |
| O'Brien, BM | 1 |
| Merkord, J | 1 |
| Weber, H | 1 |
| Jonas, L | 1 |
| Nizze, H | 1 |
| Hennighausen, G | 1 |
| Nirmala, C | 1 |
| Anand, S | 1 |
| Puvanakrishnan, R | 1 |
| Koskinen, SO | 1 |
| Ahtikoski, AM | 1 |
| Komulainen, J | 1 |
| Hesselink, MK | 1 |
| Drost, MR | 1 |
| Takala, TE | 1 |
| Eroglu, E | 1 |
| Sari, A | 1 |
| Altuntas, I | 1 |
| Delibas, N | 1 |
| Candir, C | 1 |
| Agalar, F | 1 |
| Revis, NW | 1 |
| Cameron, AJ | 1 |
| Paquet, KJ | 1 |
| Kamphausen, U | 1 |
| Weatherley, CR | 1 |
| Dale, G | 1 |
| McGurk, J | 1 |
| Walder, DN | 1 |
| Arce, V | 1 |
| Brenes, F | 1 |
| Gutiérrez, JM | 1 |
| Langner, RO | 1 |
| Bement, CL | 1 |
| Fumagalli, U | 1 |
| Trabucchi, E | 1 |
| Soligo, M | 1 |
| Rosati, R | 1 |
| Rebuffat, C | 1 |
| Tonelli, C | 1 |
| Montorsi, M | 1 |
| Ogata, I | 1 |
| Fujiwara, K | 1 |
| Gärtner, J | 1 |
| Judd, JT | 1 |
| Wexler, BC | 1 |
| Jacob, RA | 1 |
| Ofeigsson, OJ | 1 |
| Mitchell, R | 1 |
| Patrick, RS | 1 |
| Movshovich, BL | 2 |
| Mishurova, VP | 1 |
| Gvozdjak, J | 1 |
| Bada, V | 1 |
| Niederland, TR | 1 |
| Dornetzhuber, V | 1 |
| Leon, AS | 1 |
| White, FC | 1 |
| Bloor, CM | 1 |
| Saviano, MA | 1 |
| Cronk, RV | 1 |
| Flanagan, B | 1 |
| Nichols, G | 1 |
| Banks, HH | 1 |
| Hirthe, D | 1 |
| Lindenhayn, K | 1 |
41 other studies available for hydroxyproline and Necrosis
| Article | Year |
|---|---|
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
The effect of carbon monoxide releasing molecule-2 (CORM-2) on healing of ischemic colon anastomosis in rats
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Carbon Monoxide; Colon; Glutathione; Hydroxyprolin | 2021 |
The hydroalcoholic extract of watercress attenuates protein oxidation, oxidative stress, and liver damage after bile duct ligation in rats.
Topics: Animals; Antioxidants; Bile Ducts; Cholestasis, Intrahepatic; Glutathione Peroxidase; Hydroxyproline | 2019 |
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats.
Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemica | 2013 |
Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats.
Topics: Animals; Antioxidants; Cattle; Dimethylnitrosamine; Disease Progression; Glutathione; Hyaluronic Aci | 2014 |
Protective effects of seed melon extract on CCl
Topics: Actins; Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 2016 |
PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle.
Topics: Animals; Cobra Cardiotoxin Proteins; Fibrosis; Gene Expression; Hydroxyproline; Macrophages; Male; M | 2016 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, | 2010 |
COLLAGENOLYTIC ACTIVITY OF INTACT AND NECROTIC CONNECTIVE TISSUE.
Topics: Amino Acids; Collagen; Connective Tissue; Hydroxyproline; Necrosis; Rats; Research; Skin; Tissue Ext | 1964 |
A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo.
Topics: Animals; Atrophy; Dimethylnitrosamine; Disease Progression; DNA-Binding Proteins; Hydroxyproline; Li | 2003 |
Effect of richlocaine alone or in combination with energostim on the severity of endotoxemia and survival of the skin under conditions of reduced blood flow.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cell Survival; Cytochromes | 2003 |
Protective effect of verapamil on multiple hepatotoxic factors-induced liver fibrosis in rats.
Topics: Actins; Alanine Transaminase; Animals; Carbon Tetrachloride; Collagen; Dietary Fats; Disease Models, | 2007 |
Long-term protection of ischaemic myocardium by nitroglycerin ointment.
Topics: Animals; Collagen; Creatine Kinase; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Necrosi | 1984 |
Hypercalcemia of malignancy: treatment with intravenous dichloromethylene diphosphonate.
Topics: Adult; Aged; Bone Neoplasms; Bone Resorption; Calcium; Clodronic Acid; Diarrhea; Diphosphonates; Dru | 1981 |
[The problem of anastomosis of the large intestine].
Topics: Animals; Colectomy; Colon; Colostomy; Diathermy; Dogs; Female; Humans; Hydroxyproline; Intestinal Ne | 1983 |
Biochemical and morphological changes that characterise recovery from necrotising biliary pancreatitis in the opossum.
Topics: Acute Disease; Animals; Collagen; DNA; Female; Gallstones; Hydroxyproline; Immunohistochemistry; Mal | 1995 |
Effects of octreotide on healing of intestinal anastomosis following small bowel obstruction in rats.
Topics: Animals; Hydroxyproline; Intestinal Obstruction; Intestine, Small; Male; Necrosis; Octreotide; Potas | 1995 |
Radiation hepatology of the rat: the effects of the proliferation stimulus induced by subtotal hepatectomy.
Topics: Animals; Aspartate Aminotransferases; Cell Division; Dose-Response Relationship, Radiation; Hepatect | 1994 |
Wound healing process in the portio vaginalis uteri after CO2-laser treatment.
Topics: Cervix Uteri; DNA; Epithelium; Female; Humans; Hydroxyproline; Hyperplasia; Laser Therapy; Necrosis; | 1993 |
A biochemical and histological comparison of vascularized and free fat grafts in the rabbit.
Topics: Adipose Tissue; Animals; Body Water; Hydroxyproline; Necrosis; Rabbits; Surgical Flaps | 1993 |
The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats.
Topics: Administration, Oral; Amylases; Animals; Drug Synergism; Edema; Ethanol; Fibrosis; Hyaluronic Acid; | 1998 |
Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats.
Topics: Animals; Body Weight; Cell Division; Collagen; Curcumin; DNA; DNA Replication; Female; Heart; Hydrox | 1999 |
Short-term effects of forced eccentric contractions on collagen synthesis and degradation in rat skeletal muscle.
Topics: Animals; Autoradiography; Blotting, Northern; Collagen; Cyanogen Bromide; Electric Stimulation; Extr | 2002 |
The effect of GM-CSF (granulocyte macrophage colony stimulating factor) on doxorubicin induced tissue necrosis and wound healing.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Eosinophils; Fibroblasts; Granulocyte-Macrophage | 2000 |
The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits.
Topics: Animals; Aortic Coarctation; Cardiomegaly; Collagen; Hydroxyproline; Isoenzymes; Isoproterenol; L-La | 1978 |
The carbon-tetrachloride-hepatotoxicity as a model of liver damage. First report: Long-time biochemical changes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Butyryl | 1975 |
Proceedings: The use of hydroxyproline excretion in the early detection of bone necrosis.
Topics: Animals; Bone Diseases; Hydroxyproline; Necrosis; Rabbits | 1976 |
Degenerative and regenerative changes in murine skeletal muscle after injection of venom from the snake Bothrops asper: a histochemical and immunocytochemical study.
Topics: Animals; Crotalid Venoms; Hydroxyproline; Immunoenzyme Techniques; Lectins; Mice; Muscles; Necrosis; | 1991 |
Cocaine-induced changes in the biochemistry and morphology of rabbit aorta.
Topics: Animals; Cholesterol; Cocaine; Collagen; Heart; Hydroxyproline; Male; Muscle Proteins; Myocardium; N | 1991 |
Effects of intraperitoneal chemotherapy on anastomotic healing in the rat.
Topics: Anastomosis, Surgical; Animals; Hydroxyproline; Injections, Intraperitoneal; Injections, Intravenous | 1991 |
Collagen accumulation can continue with decreased prolyl hydroxylase activity in the liver.
Topics: Alanine Transaminase; Animals; Collagen; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hydr | 1985 |
[Treatment and pathogenesis of ligneous conjunctivitis (author's transl)].
Topics: Adolescent; Adult; Collagen; Conjunctiva; Conjunctivitis; Connective Tissue; Epidermal Cyst; Glycosa | 1974 |
Myocardial connective tissue metabolism in response to injury. Histological and chemical studies of mucopolysaccharide and collagen in rat hearts after isoproterenol-induced infaraction.
Topics: Animals; Arteriosclerosis; Cicatrix; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosa | 1969 |
The chemistry of dermal necrosis.
Topics: Animals; Burns, Chemical; Collagen; Croton Oil; Glycoproteins; Hexosamines; Hot Temperature; Hydroxy | 1966 |
Observations on the cold water treatment of cutaneous burns.
Topics: Animals; Back; Burns; Cell Nucleus; Collagen; Connective Tissue; Connective Tissue Cells; Cryosurger | 1972 |
[Early and late diagnostic biochemical indices in myocardial infarct].
Topics: Arteriosclerosis; Clinical Enzyme Tests; Collagen; Coronary Disease; Creatine Kinase; Haptoglobins; | 1974 |
[Biochemical pattern of the myocardium in experimental myocardial fibrosis induced by catecholamines].
Topics: Animals; Cardiomyopathies; Collagen; Glycogen; Glycolysis; Hydroxyproline; Male; Myocardium; Necrosi | 1971 |
[Basic indices of collagen metabolism in ischemic heart disease].
Topics: Arteriosclerosis; Collagen; Coronary Disease; Humans; Hydroxyproline; Myocardial Infarction; Necrosi | 1972 |
Reduced myocardial fibrosis after dimethylsulfoxide (DMSO) treatment of isoproterenol-induced myocardial necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Heart Diseases; Hexosamines; Hydroxyproline; Ischemia; Isoproterenol; M | 1971 |
Metabolic and histologic changes in femoral neck fractures leading to aseptic necrosis.
Topics: Animals; Bone Diseases; Collagen; DNA; Dogs; Femoral Neck Fractures; Hydroxyproline; Lactates; Necro | 1968 |
[Proline and hydroxyproline excretion in aseptic necroses].
Topics: Adolescent; Child; Humans; Hydroxyproline; Necrosis; Osteochondritis; Proline; Scheuermann Disease | 1966 |