Page last updated: 2024-11-06

hydroxyproline and Myopia

hydroxyproline has been researched along with Myopia in 9 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
" Meanwhile, hydroxyproline (HYP) content was measured to evaluate the degree of retinal fibrosis."4.31Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway. ( Bao, B; Bi, H; Guo, D; Li, T; Liu, J; Wang, G; Xin, J; Yang, Z, 2023)
"The hydroxyproline level was significantly lower only at the posterior pole (-11."1.29Reduced extracellular matrix in mammalian sclera with induced myopia. ( Norton, TT; Rada, JA, 1995)
"Cleft palate (28%), micrognathia (17%) and sensorineural hearing loss (9%) are also liable to occur in affected individuals."1.25Stickler's syndrome (hereditary progressive arthro-ophthalmopathy). ( Polomeno, RC; Popkin, JS, 1974)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Bao, B1
Liu, J1
Li, T1
Yang, Z1
Wang, G1
Xin, J1
Bi, H1
Guo, D1
Liu, HH1
Gentle, A1
Jobling, AI1
McBrien, NA1
Avetisov, ES1
Savitskaya, NF1
Vinetskaya, MI1
Iomdina, EN1
Butiukova, VA1
Eremin, VP1
Dzhumaeva, TI1
Rada, JA2
Matthews, AL1
Norton, TT1
Douglas, EP1
Popkin, JS1
Polomeno, RC1
Smith, ER1
Mason, MM1
Epstein, E1

Other Studies

9 other studies available for hydroxyproline and Myopia

ArticleYear
Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway.
    Archives of biochemistry and biophysics, 2023, 07-15, Volume: 743

    Topics: Animals; Collagen; Fibrosis; Guinea Pigs; Hydroxyproline; Matrix Metalloproteinase 2; Myopia; Phosph

2023
Inhibition of matrix metalloproteinase activity in the chick sclera and its effect on myopia development.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Animals; Animals, Newborn; Biometry; Chickens; Collagen; Hydroxyproline; Matrix Metalloproteinase In

2010
A study of biochemical and biomechanical qualities of normal and myopic eye sclera in humans of different age groups.
    Metabolic, pediatric, and systemic ophthalmology, 1983, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Collagen; Elasticity; Hexosamines; Hu

1983
[Plasma hydroxyproline in myopia].
    Oftalmologicheskii zhurnal, 1982, Volume: 37, Issue:5

    Topics: Adult; Female; Humans; Hydroxyproline; Male; Myopia

1982
Visual deprivation upregulates extracellular matrix synthesis by chick scleral chondrocytes.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:5

    Topics: Animals; Cartilage; Cells, Cultured; Chickens; Collagen; Dactinomycin; Extracellular Matrix; Glycosa

1994
Reduced extracellular matrix in mammalian sclera with induced myopia.
    Vision research, 1995, Volume: 35, Issue:9

    Topics: Animals; Biometry; Cornea; DNA; Extracellular Matrix; Female; Glycosaminoglycans; Hydroxyproline; Ma

1995
Hyperprolinaemia and gyrate atrophy of the choroid and retina in members of the same family.
    The British journal of ophthalmology, 1985, Volume: 69, Issue:8

    Topics: Adult; Atrophy; Child; Choroid; Chromosome Aberrations; Chromosome Disorders; Female; Fundus Oculi;

1985
Stickler's syndrome (hereditary progressive arthro-ophthalmopathy).
    Canadian Medical Association journal, 1974, Nov-16, Volume: 111, Issue:10

    Topics: Adolescent; Child; Child, Preschool; Cleft Palate; Deafness; Genes, Dominant; Genetic Counseling; Hi

1974
The ocular effects of repeated dermal applications of dimethyl sulfoxide to dogs and monkeys.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2

    Topics: Animals; Blood Chemical Analysis; Dimethyl Sulfoxide; Dogs; Eye; Halitosis; Haplorhini; Hydroxyproli

1969