hydroxyproline has been researched along with Myocardial Ischemia in 5 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic ischemic heart disease is associated with myocardial hypoperfusion." | 1.39 | Impaired mitochondrial function in chronically ischemic human heart. ( Dela, F; Hansen, CN; Hey-Mogensen, M; Køber, L; Larsen, S; Prats, C; Steinbrüchel, D; Stride, N, 2013) |
| "Ischemic mitral regurgitation or ventricular wall motion abnormalities will alter the stress distribution in the mitral valve." | 1.30 | Altered collagen concentration in mitral valve leaflets: biochemical and finite element analysis. ( Cochran, RP; Kunzelman, KS; Quick, DW, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stride, N | 1 |
| Larsen, S | 1 |
| Hey-Mogensen, M | 1 |
| Hansen, CN | 1 |
| Prats, C | 1 |
| Steinbrüchel, D | 1 |
| Køber, L | 1 |
| Dela, F | 1 |
| Zhang, J | 1 |
| Qi, YF | 1 |
| Geng, B | 1 |
| Pan, CS | 1 |
| Zhao, J | 1 |
| Chen, L | 1 |
| Yang, J | 1 |
| Chang, JK | 1 |
| Tang, CS | 1 |
| Agnoletti, G | 1 |
| Cargnoni, A | 1 |
| Agnoletti, L | 1 |
| Di Marcello, M | 1 |
| Balzarini, P | 1 |
| Pasini, E | 1 |
| Gitti, G | 1 |
| Martina, P | 1 |
| Ardesi, R | 1 |
| Ferrari, R | 1 |
| Kunzelman, KS | 1 |
| Quick, DW | 1 |
| Cochran, RP | 1 |
| Asemu, G | 1 |
| Neckár, J | 1 |
| Szárszoi, O | 1 |
| Papousek, F | 1 |
| Ostádal, B | 1 |
| Kolar, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of an Early Phase Single Bolus r-SAK for Acute Myocardial Infarction: a Multi-center Randomized Clinical Trial (OPTIMA-5)[NCT05023681] | Phase 4 | 200 participants (Actual) | Interventional | 2021-10-29 | Completed | ||
| A Single Bolus r-SAK Prior to Primary PCI for ST-elevation Myocardial Infarction (OPTIMA-5): 1-Year Follow-up[NCT05649696] | Phase 4 | 210 participants (Actual) | Interventional | 2021-10-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for hydroxyproline and Myocardial Ischemia
| Article | Year |
|---|---|
Impaired mitochondrial function in chronically ischemic human heart.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Aged; Blood Glucose; Blotting, Western; Cholesterol; Chronic Disea | 2013 |
Effect of relaxin on myocardial ischemia injury induced by isoproterenol.
Topics: Animals; Cardiomegaly; Creatine Kinase; Disease Models, Animal; Endothelins; Gene Expression; Heart; | 2005 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Altered collagen concentration in mitral valve leaflets: biochemical and finite element analysis.
Topics: Animals; Biochemical Phenomena; Biochemistry; Chordae Tendineae; Collagen; Elasticity; Finite Elemen | 1998 |
Effects of adaptation to intermittent high altitude hypoxia on ischemic ventricular arrhythmias in rats.
Topics: Adaptation, Physiological; Altitude; Animals; Body Weight; Heart; Hydroxyproline; Hypoxia; In Vitro | 2000 |