hydroxyproline has been researched along with Muscular Dystrophy, Duchenne in 9 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibrosis is a common pathological feature observed in muscle from patients with Duchenne muscular dystrophy and in mdx diaphragm." | 5.33 | Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle. ( Gosselin, LE; Williams, JE, 2006) |
| "Fibrosis is a common pathological feature observed in muscle from patients with Duchenne muscular dystrophy and in mdx diaphragm." | 1.33 | Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle. ( Gosselin, LE; Williams, JE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, LR | 2 |
| Barton, ER | 2 |
| Hammers, DW | 1 |
| Sweeney, HL | 1 |
| Schill, KE | 1 |
| Altenberger, AR | 1 |
| Lowe, J | 1 |
| Periasamy, M | 1 |
| Villamena, FA | 1 |
| Rafael-Fortney, JA | 1 |
| Devor, ST | 1 |
| Gargioli, C | 1 |
| Coletta, M | 1 |
| De Grandis, F | 1 |
| Cannata, SM | 1 |
| Cossu, G | 1 |
| Bostick, B | 1 |
| Yue, Y | 1 |
| Duan, D | 3 |
| Garlich, MW | 1 |
| Baltgalvis, KA | 1 |
| Call, JA | 1 |
| Dorsey, LL | 1 |
| Lowe, DA | 1 |
| Hakim, CH | 2 |
| Grange, RW | 1 |
| Gosselin, LE | 1 |
| Williams, JE | 1 |
9 other studies available for hydroxyproline and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.
Topics: Animals; Biomechanical Phenomena; Collagen; Diaphragm; Disease Models, Animal; Elasticity; Extracell | 2014 |
Increased collagen cross-linking is a signature of dystrophin-deficient muscle.
Topics: Adolescent; Animals; Child; Collagen; Diaphragm; Dogs; Female; Humans; Hydroxyproline; Male; Mice; M | 2016 |
Muscle damage, metabolism, and oxidative stress in mdx mice: Impact of aerobic running.
Topics: Animals; Collagen; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Glutathione | 2016 |
PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle.
Topics: Animals; Blotting, Western; Cell- and Tissue-Based Therapy; Collagen; Fibroblasts; Fluorescent Antib | 2008 |
Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy.
Topics: Animals; Blood Pressure; Blood Volume; Cardiomyopathy, Dilated; Electrocardiography; Female; Fibrosi | 2010 |
Plantarflexion contracture in the mdx mouse.
Topics: Animals; Collagen; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Mice; Mice, Inbred mdx; M | 2010 |
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Biomechanical Phenomena; Body Weight; Disease Mod | 2011 |
Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice.
Topics: Age Factors; Animals; Biomechanical Phenomena; Body Weight; Disease Models, Animal; Dystrophin; Elas | 2013 |
Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle.
Topics: Animals; Collagen Type I; Collagen Type III; Diaphragm; Disease Models, Animal; Enzyme Inhibitors; F | 2006 |