hydroxyproline has been researched along with Marfan Syndrome in 43 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The type III/I + III collagen ratio was studied in intima-medial samples of ascending aortas obtained from patients with the Marfan syndrome or other annulo-aortic ectasia (dilatation of the ascending aorta) and from control subjects, using electrophoretic analysis of cyanogen bromide peptides." | 3.67 | Collagen in human aorta. Changes in the type III/I ratio and concentration of the reducible crosslink, dehydrohydroxylysinonorleucine in ascending aorta from healthy subjects of different age and patients with annulo-aortic ectasia. ( Halme, T; Peltonen, J; Penttinen, R; Sims, TJ; Vihersaari, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (93.02) | 18.7374 |
| 1990's | 2 (4.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindeman, JH | 1 |
| Ashcroft, BA | 1 |
| Beenakker, JW | 1 |
| van Es, M | 1 |
| Koekkoek, NB | 1 |
| Prins, FA | 1 |
| Tielemans, JF | 1 |
| Abdul-Hussien, H | 1 |
| Bank, RA | 1 |
| Oosterkamp, TH | 1 |
| SJOERDSMA, A | 1 |
| DAVIDSON, JD | 1 |
| UDENFRIEND, S | 1 |
| MITOMA, C | 1 |
| SCHMIDT, M | 1 |
| BARZILAI, D | 1 |
| BEN-MOSHE, H | 1 |
| Iavanainen, M | 1 |
| Laitinen, O | 3 |
| Palo, J | 1 |
| Lind, J | 1 |
| Hoynck van Papendrecht, HP | 1 |
| Valentini, F | 1 |
| Colombo, F | 1 |
| Pozzoli, G | 1 |
| Gilardi, A | 1 |
| Radice, M | 1 |
| Mariotti, GC | 1 |
| Vigo, PL | 1 |
| Corghi, E | 1 |
| Uitto, J | 4 |
| Lichtenstein, JR | 1 |
| Prockop, DJ | 2 |
| Kivirikko, KI | 2 |
| Tuderman, L | 1 |
| Guzman, NA | 1 |
| Takeuchi, T | 1 |
| Francis, G | 1 |
| Donnelly, PV | 1 |
| Di Ferrante, N | 1 |
| Michael, EB | 1 |
| Gapuzov, VV | 2 |
| Rudakov, SS | 1 |
| Verovskiĭ, VA | 1 |
| Prozorovskaia, NN | 1 |
| Razuvaev, MK | 1 |
| Igarashi, S | 1 |
| McIntosh, CJ | 1 |
| Davis, PF | 1 |
| Ryan, PA | 1 |
| Stehbens, WE | 1 |
| Müller, KP | 1 |
| Nerlich, AG | 1 |
| Kunze, D | 1 |
| Müller, PK | 1 |
| Savunen, T | 1 |
| Halme, T | 1 |
| Peltonen, J | 1 |
| Sims, TJ | 1 |
| Vihersaari, T | 1 |
| Penttinen, R | 1 |
| Perejda, AJ | 1 |
| Abraham, PA | 1 |
| Carnes, WH | 1 |
| Coulson, WF | 1 |
| Hirthe, D | 1 |
| Lindenhayn, K | 1 |
| Deckers, PF | 2 |
| Svarts, EI | 1 |
| Utekhina, EV | 1 |
| Semiachkina, AN | 1 |
| Barashnev, IuI | 1 |
| Bańkowski, E | 1 |
| Galasiński, W | 1 |
| Grant, ME | 1 |
| Priest, RE | 1 |
| Moinuddin, JF | 1 |
| Priest, JH | 1 |
| Dinulescu, E | 1 |
| Ganea, E | 1 |
| Olteanu, M | 1 |
| Nusgens, B | 1 |
| Lapiere, CM | 1 |
| Ege, P | 1 |
| Böhmer, T | 1 |
| Lipton, RA | 1 |
| Greenwald, RA | 1 |
| Seriff, NS | 1 |
| Yamori, K | 1 |
| Segrest, JP | 1 |
| Cunningham, LW | 1 |
| Iivanainen, M | 1 |
| Hannuksela, M | 1 |
| Bessière, E | 1 |
| Vérin, P | 1 |
| Broustet, A | 1 |
| Le Rebeller, MJ | 1 |
| Jones, CR | 1 |
| Van Itallie, TB | 1 |
| Stevenson, SS | 1 |
| Pigman, WW | 1 |
| Ravenni, G | 1 |
| Rubegni, M | 1 |
| Gennari, C | 1 |
| Forconi, S | 1 |
| Macek, M | 1 |
| Hurych, J | 1 |
| Chvapil, M | 1 |
| Kadlecová, V | 1 |
6 reviews available for hydroxyproline and Marfan Syndrome
| Article | Year |
|---|---|
Defects in the biochemistry of collagen in diseases of connective tissue.
Topics: Aortic Diseases; Bone and Bones; Brain Diseases; Collagen; Connective Tissue; Cutis Laxa; Ehlers-Dan | 1976 |
[Biosynthesis of collagen].
Topics: Adenocarcinoma, Scirrhous; Adult; Amino Acids; Animals; Ascorbic Acid; Cattle; Child; Collagen; Coll | 1975 |
Biochemistry of the elastic fibers in normal connective tissues and its alterations in diseases.
Topics: Amino Acids; Arteriosclerosis; Chemical Phenomena; Chemistry; Collagen Diseases; Connective Tissue; | 1979 |
The biosynthesis of collagen. 3.
Topics: Aging; Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Collagen; Collagen | 1972 |
[Urine hydroxyproline a review].
Topics: Acromegaly; Bone Resorption; Carbon Isotopes; Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hyp | 1968 |
The biosynthesis of collagen.
Topics: Acromegaly; Ascorbic Acid Deficiency; Carbon Isotopes; Collagen; Ehlers-Danlos Syndrome; Hydroxylati | 1971 |
37 other studies available for hydroxyproline and Marfan Syndrome
| Article | Year |
|---|---|
Distinct defects in collagen microarchitecture underlie vessel-wall failure in advanced abdominal aneurysms and aneurysms in Marfan syndrome.
Topics: Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Arteries; Collagen; Humans; Hydroxyproline; Marf | 2010 |
Increased excretion of hydroxyproline in Marfan's syndrome.
Topics: Arachnodactyly; Humans; Hydroxyproline; Marfan Syndrome; Proline | 1958 |
EXCRETION of hydroxyproline in Marfan's syndrome.
Topics: Arachnodactyly; Biological Transport; Humans; Hydroxyproline; Marfan Syndrome; Proline | 1959 |
[MARFAN'S SYNDROME].
Topics: Anthropometry; Arachnodactyly; Blood Chemical Analysis; Chromosome Aberrations; Chromosome Disorders | 1963 |
Diagnostic criteria in Marfan's disease.
Topics: Adolescent; Adult; Cardiomyopathies; Child; Child, Preschool; Consanguinity; Eye Diseases; Female; H | 1967 |
Obstetrical complications in a patient with the Marfan syndrome.
Topics: Adult; Amniotic Fluid; Female; Humans; Hydroxyproline; Marfan Syndrome; Pregnancy; Pregnancy Complic | 1984 |
[Idiopathic mitral valve prolapse and urinary excretion of hydroxyproline].
Topics: Adult; Age Factors; Connective Tissue; Creatinine; Female; Humans; Hydroxyproline; Male; Marfan Synd | 1980 |
The biosynthesis of collagen and its disorders (second of two parts).
Topics: Aging; Animals; Colchicine; Collagen; Collagen Diseases; Ehlers-Danlos Syndrome; Glucosyltransferase | 1979 |
Abnormally soluble collagen produced in fibroblasts cultures.
Topics: Benzopyrans; Cells, Cultured; Collagen; Cutis Laxa; Ehlers-Danlos Syndrome; Fibroblasts; Humans; Hyd | 1976 |
Clinical applications of urinary hydroxyproline determination.
Topics: Adolescent; Adult; Age Factors; Aged; Bone Diseases; Chemistry Techniques, Analytical; Child; Collag | 1975 |
Studies on the biochemical basis of the Marfan syndrome--a review.
Topics: Aorta; Collagen; Elastic Tissue; Fibroblasts; Heart Valves; Humans; Hydroxyproline; Marfan Syndrome; | 1976 |
[The determination of hydroxyproline in daily urine].
Topics: Adolescent; Adult; Child; Circadian Rhythm; Humans; Hydroxyproline; Marfan Syndrome | 1990 |
[Early diagnosis of progression of funnel chest in children].
Topics: Adolescent; Child; Child, Preschool; Ehlers-Danlos Syndrome; Funnel Chest; Humans; Hydroxyproline; I | 1990 |
[Significance of hydroxyproline analysis in clinical tests].
Topics: Adolescent; Adult; Aged; Gelatin; Humans; Hydroxyproline; Hyperparathyroidism; Hyperthyroidism; Marf | 1989 |
Urinary excretion of connective tissue protein markers in arterial disease.
Topics: Arteries; Collagen; Desmosine; Elastin; Humans; Hydroxyproline; Marfan Syndrome; Solubility; Vascula | 1989 |
Studies on collagen metabolism in the Marfan syndrome.
Topics: Adolescent; Adult; Amino Acids; Cells, Cultured; Child; Collagen; Female; Fibroblasts; Humans; Hydro | 1987 |
Annulo-aortic ectasia. A clinical, structural and biochemical study.
Topics: Adolescent; Adult; Aged; Aorta; Aortic Aneurysm; Aortic Diseases; Aortic Valve Insufficiency; Child; | 1986 |
Collagen in human aorta. Changes in the type III/I ratio and concentration of the reducible crosslink, dehydrohydroxylysinonorleucine in ascending aorta from healthy subjects of different age and patients with annulo-aortic ectasia.
Topics: Adolescent; Adult; Aorta; Borohydrides; Child; Chromatography, Ion Exchange; Collagen; Cyanogen Brom | 1986 |
Marfan's syndrome: structural, biochemical, and mechanical studies of the aortic media.
Topics: Adult; Aorta; Aortic Aneurysm; Aortic Dissection; Collagen; Elastin; Glycosaminoglycans; Humans; Hyd | 1985 |
[A contribution to the Ehlers-Danlos syndrome].
Topics: Adolescent; Collagen Diseases; Diagnosis, Differential; Ehlers-Danlos Syndrome; Female; Glycosaminog | 1967 |
[Biochemical study of Marfan's syndrome].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Collagen; Female; Glycosaminoglycans; | 1971 |
[Clinical-biochemical studies of Marfan's syndrome].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Circadian Rhythm; Connective Tissue; Female | 1973 |
[Principles of diagnosis of Marfan's syndrome].
Topics: Adolescent; Child; Child, Preschool; Female; Glycosaminoglycans; Humans; Hydroxyproline; Infant; Mal | 1974 |
Hydroxyproline and collagen metabolism. Clinical implications.
Topics: Adolescent; Adult; Aged; Aging; Blood Proteins; Child; Child, Preschool; Collagen; Female; Gelatin; | 1965 |
[Collagen biosynthesis (author's transl)].
Topics: Amino Acid Sequence; Amino Acids; Biological Transport, Active; Cell Membrane Permeability; Collagen | 1974 |
Letter: Collagen of Marfan syndrome is abnormally soluble.
Topics: Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxyproline; Marfan Syndrome; Proline; Solubility | 1973 |
[Automated determination of free and combined hydroxyproline].
Topics: Acromegaly; Autoanalysis; Colorimetry; Humans; Hydroxyproline; Marfan Syndrome | 1972 |
The relationship between proline and hydroxyproline urinary excretion in human as an index of collagen catabolism.
Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatogra | 1973 |
[Biochemical abnormalities in Marfan's syndrome].
Topics: Adolescent; Adult; Child; Female; Humans; Hydroxyproline; Joint Dislocations; Male; Marfan Syndrome; | 1972 |
Pneumothorax and bilateral honeycombed lung in Marfan syndrome. Report of a case and review of the pulmonary abnormalities in this disorder.
Topics: Adolescent; Humans; Hydroxyproline; Male; Marfan Syndrome; Pedigree; Pneumothorax; Radiography; Resp | 1971 |
[Studies on free amino acids in the urine of patients with ocular diseases. II. Hydroxyproline in the urine of the patients with Marfan's syndrome].
Topics: Adult; Amino Acids; Chromatography; Diagnosis, Differential; Female; Homocystinuria; Humans; Hydroxy | 1969 |
Variations in human urinary O-hydroxylysyl glycoside levels and their relationship to collagen metabolism.
Topics: Achondroplasia; Adolescent; Adult; Aged; Amino Acids; Arthritis, Rheumatoid; Bone and Bones; Bronchi | 1970 |
Collagen metabolism of the skin in Marfan's syndrome.
Topics: Adolescent; Adult; Biopsy; Carbon Isotopes; Collagen; Humans; Hydroxyproline; Marfan Syndrome; Middl | 1968 |
[Cutaneous biopsy and study of urinary amino acids in crystalline lens ectopia].
Topics: Abnormalities, Multiple; Adolescent; Aged; Biopsy; Body Constitution; Ehlers-Danlos Syndrome; Finger | 1968 |
Decrease in hydroxyproline excretion in a patient with Marfan's syndrome after methandrostenolone therapy.
Topics: Adult; Collagen; Female; Humans; Hydroxyproline; Marfan Syndrome; Methandrostenolone | 1969 |
[Hydroxyprolinuria in Marfan's syndrome].
Topics: Calcium; Humans; Hydroxyproline; Marfan Syndrome | 1965 |
Study of fibroblasts in Marfan's syndrome.
Topics: Adult; Child, Preschool; Chromosomes; Collagen; Culture Techniques; Female; Fibroblasts; Humans; Hyd | 1966 |