hydroxyproline has been researched along with Liver Cirrhosis, Biliary in 11 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
Excerpt | Relevance | Reference |
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"To investigate the effects of carvedilol on inflammation, apoptosis, and hepatic fibrosis caused by biliary cirrhosis and its mechanisms in mice." | 7.85 | Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress. ( Gao, P; Meng, RR; Si, JY; Yang, B; Yu, HY, 2017) |
"To investigate the effects of carvedilol on inflammation, apoptosis, and hepatic fibrosis caused by biliary cirrhosis and its mechanisms in mice." | 3.85 | Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress. ( Gao, P; Meng, RR; Si, JY; Yang, B; Yu, HY, 2017) |
"The model of biliary cirrhosis by bile duct ligation was further characterized using PIIIP, 7S-collagen as well as standard enzymes in the serum, prolyl 4-hydroxylase and total hydroxyproline in the liver and light microscopical histology." | 3.68 | Fibrosis of the liver in rats induced by bile duct ligation. Effects of inhibition by prolyl 4-hydroxylase. ( Böker, K; Günzler, V; Kaule, G; Schmidt, E; Schwarting, G, 1991) |
"Fibrosis was assessed by measuring the liver hydroxyproline content." | 1.46 | Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans. ( Arauz, J; Favari, L; Galicia-Moreno, M; Hernández-Aquino, E; Muriel, P; Segovia, J; Zarco, N, 2017) |
"Among the bone resorption markers, serum ICTP and urinary PYR, DPYR, HYP, NTX, and CTX levels were significantly higher in patients than in controls." | 1.30 | Collagen-related markers of bone turnover reflect the severity of liver fibrosis in patients with primary biliary cirrhosis. ( Alvarez, L; Ballesta, AM; Guañabens, N; Martínez de Osaba, MJ; Monegal, A; Parés, A; Peris, P; Rodés, J, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (18.18) | 18.7374 |
1990's | 3 (27.27) | 18.2507 |
2000's | 4 (36.36) | 29.6817 |
2010's | 2 (18.18) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Arauz, J | 1 |
Zarco, N | 1 |
Hernández-Aquino, E | 1 |
Galicia-Moreno, M | 1 |
Favari, L | 1 |
Segovia, J | 1 |
Muriel, P | 2 |
Gao, P | 1 |
Yang, B | 1 |
Yu, HY | 1 |
Meng, RR | 1 |
Si, JY | 1 |
Deheza, R | 1 |
Omenetti, A | 1 |
Yang, L | 1 |
Li, YX | 1 |
McCall, SJ | 1 |
Jung, Y | 1 |
Sicklick, JK | 1 |
Huang, J | 1 |
Choi, S | 1 |
Suzuki, A | 1 |
Diehl, AM | 1 |
Fickert, P | 1 |
Stöger, U | 1 |
Fuchsbichler, A | 1 |
Moustafa, T | 1 |
Marschall, HU | 1 |
Weiglein, AH | 1 |
Tsybrovskyy, O | 1 |
Jaeschke, H | 1 |
Zatloukal, K | 1 |
Denk, H | 1 |
Trauner, M | 1 |
Guañabens, N | 2 |
Parés, A | 2 |
Navasa, M | 1 |
Martínez de Osaba, MJ | 2 |
Hernández, ME | 1 |
Muñoz, J | 1 |
Rodés, J | 2 |
Alvarez, L | 1 |
Monegal, A | 1 |
Peris, P | 1 |
Ballesta, AM | 1 |
Raetsch, C | 1 |
Jia, JD | 1 |
Boigk, G | 1 |
Bauer, M | 1 |
Hahn, EG | 1 |
Riecken, EO | 1 |
Schuppan, D | 1 |
Koyama, K | 1 |
Muto, I | 1 |
Yamauchi, H | 1 |
Takagi, Y | 1 |
Anezaki, T | 1 |
Böker, K | 1 |
Schwarting, G | 1 |
Kaule, G | 1 |
Günzler, V | 1 |
Schmidt, E | 1 |
Cerda, JJ | 1 |
Toskes, PP | 1 |
Shopa, NA | 1 |
Wilkinson, JH | 1 |
1 trial available for hydroxyproline and Liver Cirrhosis, Biliary
Article | Year |
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Cyclosporin A increases the biochemical markers of bone remodeling in primary biliary cirrhosis.
Topics: Adult; Aged; Alkaline Phosphatase; Bilirubin; Biomarkers; Bone Density; Calcifediol; Calcitriol; Cal | 1994 |
10 other studies available for hydroxyproline and Liver Cirrhosis, Biliary
Article | Year |
---|---|
Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans.
Topics: Actins; Animals; Antioxidants; Bile Ducts; Caffeine; Coffee; Connective Tissue Growth Factor; Diseas | 2017 |
Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress.
Topics: Actins; Animals; Carvedilol; Collagen Type I; Endoplasmic Reticulum Stress; Hydroxyproline; Liver Ci | 2017 |
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine.
Topics: Administration, Oral; Alanine Transaminase; Alcohol Deterrents; Animals; Bilirubin; Cholestasis, Ext | 2003 |
Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
Topics: Animals; Bile Ducts; Biomarkers; Cell Survival; Cells, Cultured; Disease Models, Animal; Epithelium; | 2007 |
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Cholangitis, Sclerosing; Cholesterol; Dicarbethoxydihydro | 2007 |
Collagen-related markers of bone turnover reflect the severity of liver fibrosis in patients with primary biliary cirrhosis.
Topics: Acid Phosphatase; Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone and Bones; Bone Dens | 1998 |
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
Topics: Administration, Oral; Animals; Cholestasis; Chronic Disease; Collagen; Cytokines; DNA Probes; DNA, C | 2002 |
Biochemical study of fibrosis in the rat liver in biliary obstruction.
Topics: Animals; Carbon Radioisotopes; Cholestasis; Collagen; Common Bile Duct; Hexosamines; Hydroxyproline; | 1975 |
Fibrosis of the liver in rats induced by bile duct ligation. Effects of inhibition by prolyl 4-hydroxylase.
Topics: Animals; Biomarkers; Cholinesterases; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Biliary; Liv | 1991 |
The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Bone Diseases; Cholest | 1970 |