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hydroxyproline and Liver Cirrhosis, Biliary

hydroxyproline has been researched along with Liver Cirrhosis, Biliary in 11 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of carvedilol on inflammation, apoptosis, and hepatic fibrosis caused by biliary cirrhosis and its mechanisms in mice."7.85Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress. ( Gao, P; Meng, RR; Si, JY; Yang, B; Yu, HY, 2017)
"To investigate the effects of carvedilol on inflammation, apoptosis, and hepatic fibrosis caused by biliary cirrhosis and its mechanisms in mice."3.85Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress. ( Gao, P; Meng, RR; Si, JY; Yang, B; Yu, HY, 2017)
"The model of biliary cirrhosis by bile duct ligation was further characterized using PIIIP, 7S-collagen as well as standard enzymes in the serum, prolyl 4-hydroxylase and total hydroxyproline in the liver and light microscopical histology."3.68Fibrosis of the liver in rats induced by bile duct ligation. Effects of inhibition by prolyl 4-hydroxylase. ( Böker, K; Günzler, V; Kaule, G; Schmidt, E; Schwarting, G, 1991)
"Fibrosis was assessed by measuring the liver hydroxyproline content."1.46Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans. ( Arauz, J; Favari, L; Galicia-Moreno, M; Hernández-Aquino, E; Muriel, P; Segovia, J; Zarco, N, 2017)
"Among the bone resorption markers, serum ICTP and urinary PYR, DPYR, HYP, NTX, and CTX levels were significantly higher in patients than in controls."1.30Collagen-related markers of bone turnover reflect the severity of liver fibrosis in patients with primary biliary cirrhosis. ( Alvarez, L; Ballesta, AM; Guañabens, N; Martínez de Osaba, MJ; Monegal, A; Parés, A; Peris, P; Rodés, J, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arauz, J1
Zarco, N1
Hernández-Aquino, E1
Galicia-Moreno, M1
Favari, L1
Segovia, J1
Muriel, P2
Gao, P1
Yang, B1
Yu, HY1
Meng, RR1
Si, JY1
Deheza, R1
Omenetti, A1
Yang, L1
Li, YX1
McCall, SJ1
Jung, Y1
Sicklick, JK1
Huang, J1
Choi, S1
Suzuki, A1
Diehl, AM1
Fickert, P1
Stöger, U1
Fuchsbichler, A1
Moustafa, T1
Marschall, HU1
Weiglein, AH1
Tsybrovskyy, O1
Jaeschke, H1
Zatloukal, K1
Denk, H1
Trauner, M1
Guañabens, N2
Parés, A2
Navasa, M1
Martínez de Osaba, MJ2
Hernández, ME1
Muñoz, J1
Rodés, J2
Alvarez, L1
Monegal, A1
Peris, P1
Ballesta, AM1
Raetsch, C1
Jia, JD1
Boigk, G1
Bauer, M1
Hahn, EG1
Riecken, EO1
Schuppan, D1
Koyama, K1
Muto, I1
Yamauchi, H1
Takagi, Y1
Anezaki, T1
Böker, K1
Schwarting, G1
Kaule, G1
Günzler, V1
Schmidt, E1
Cerda, JJ1
Toskes, PP1
Shopa, NA1
Wilkinson, JH1

Trials

1 trial available for hydroxyproline and Liver Cirrhosis, Biliary

ArticleYear
Cyclosporin A increases the biochemical markers of bone remodeling in primary biliary cirrhosis.
    Journal of hepatology, 1994, Volume: 21, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Bilirubin; Biomarkers; Bone Density; Calcifediol; Calcitriol; Cal

1994

Other Studies

10 other studies available for hydroxyproline and Liver Cirrhosis, Biliary

ArticleYear
Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans.
    Nutrition research (New York, N.Y.), 2017, Volume: 40

    Topics: Actins; Animals; Antioxidants; Bile Ducts; Caffeine; Coffee; Connective Tissue Growth Factor; Diseas

2017
Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:24

    Topics: Actins; Animals; Carvedilol; Collagen Type I; Endoplasmic Reticulum Stress; Hydroxyproline; Liver Ci

2017
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine.
    Liver international : official journal of the International Association for the Study of the Liver, 2003, Volume: 23, Issue:4

    Topics: Administration, Oral; Alanine Transaminase; Alcohol Deterrents; Animals; Bilirubin; Cholestasis, Ext

2003
Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:5

    Topics: Animals; Bile Ducts; Biomarkers; Cell Survival; Cells, Cultured; Disease Models, Animal; Epithelium;

2007
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
    The American journal of pathology, 2007, Volume: 171, Issue:2

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Cholangitis, Sclerosing; Cholesterol; Dicarbethoxydihydro

2007
Collagen-related markers of bone turnover reflect the severity of liver fibrosis in patients with primary biliary cirrhosis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:4

    Topics: Acid Phosphatase; Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone and Bones; Bone Dens

1998
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
    Gut, 2002, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Cholestasis; Chronic Disease; Collagen; Cytokines; DNA Probes; DNA, C

2002
Biochemical study of fibrosis in the rat liver in biliary obstruction.
    The Tohoku journal of experimental medicine, 1975, Volume: 116, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cholestasis; Collagen; Common Bile Duct; Hexosamines; Hydroxyproline;

1975
Fibrosis of the liver in rats induced by bile duct ligation. Effects of inhibition by prolyl 4-hydroxylase.
    Journal of hepatology, 1991, Volume: 13 Suppl 3

    Topics: Animals; Biomarkers; Cholinesterases; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Biliary; Liv

1991
The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1970, Volume: 27, Issue:3

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Bone Diseases; Cholest

1970