Page last updated: 2024-11-06

hydroxyproline and Leukemia

hydroxyproline has been researched along with Leukemia in 2 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Collagenolytic activity in leukocytes and plasma concentration of hydroxyproline were estimated in 80 patients with leukemias and Hodgkin's disease and in 20 healthy individuals."3.66Collagenolytic activity in leukocytes isolated from patients with leukemias and Hodgkin's disease. ( Drózdz, M; Kucharz, E, 1978)
"This was associated with a decrease in bone resorption as judged by decreases in urinary excretion of hydroxyproline and calcium."1.27Treatment of the hypercalcaemia of malignancy with intravenous clodronate. ( Gray, RE; Greaves, M; Hamdy, NA; Kanis, JA; McCloskey, EV; Neil, FE; Preston, FE; Urwin, GH; Yates, AJ, 1987)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kucharz, E1
Drózdz, M1
Urwin, GH1
Yates, AJ1
Gray, RE1
Hamdy, NA1
McCloskey, EV1
Preston, FE1
Greaves, M1
Neil, FE1
Kanis, JA1

Other Studies

2 other studies available for hydroxyproline and Leukemia

ArticleYear
Collagenolytic activity in leukocytes isolated from patients with leukemias and Hodgkin's disease.
    Neoplasma, 1978, Volume: 25, Issue:5

    Topics: Hodgkin Disease; Humans; Hydroxyproline; Leukemia; Leukocytes; Microbial Collagenase

1978
Treatment of the hypercalcaemia of malignancy with intravenous clodronate.
    Bone, 1987, Volume: 8 Suppl 1

    Topics: Adult; Aged; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Female; Humans; Hydroxyprolin

1987