hydroxyproline has been researched along with Leukemia in 2 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Collagenolytic activity in leukocytes and plasma concentration of hydroxyproline were estimated in 80 patients with leukemias and Hodgkin's disease and in 20 healthy individuals." | 3.66 | Collagenolytic activity in leukocytes isolated from patients with leukemias and Hodgkin's disease. ( Drózdz, M; Kucharz, E, 1978) |
| "This was associated with a decrease in bone resorption as judged by decreases in urinary excretion of hydroxyproline and calcium." | 1.27 | Treatment of the hypercalcaemia of malignancy with intravenous clodronate. ( Gray, RE; Greaves, M; Hamdy, NA; Kanis, JA; McCloskey, EV; Neil, FE; Preston, FE; Urwin, GH; Yates, AJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kucharz, E | 1 |
| Drózdz, M | 1 |
| Urwin, GH | 1 |
| Yates, AJ | 1 |
| Gray, RE | 1 |
| Hamdy, NA | 1 |
| McCloskey, EV | 1 |
| Preston, FE | 1 |
| Greaves, M | 1 |
| Neil, FE | 1 |
| Kanis, JA | 1 |
2 other studies available for hydroxyproline and Leukemia
| Article | Year |
|---|---|
Collagenolytic activity in leukocytes isolated from patients with leukemias and Hodgkin's disease.
Topics: Hodgkin Disease; Humans; Hydroxyproline; Leukemia; Leukocytes; Microbial Collagenase | 1978 |
Treatment of the hypercalcaemia of malignancy with intravenous clodronate.
Topics: Adult; Aged; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Female; Humans; Hydroxyprolin | 1987 |