hydroxyproline has been researched along with Klinefelter Syndrome in 6 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Measurements made in patients with Klinefelter's syndrome were compared to those obtained in age-matched normal male volunteers." | 1.28 | Osteoporosis and Klinefelter's syndrome. ( Horowitz, M; Morris, HA; Need, AG; Nordin, BE; O'Loughlin, PD; Wishart, JM, 1992) |
| "In patients with Klinefelter's syndrome at the age below 11 and above 17 years normal hydroxyproline values were observed." | 1.26 | Urinary total hydroxyproline excretion in patients with Turner's syndrome and Klinefelter's syndrome. ( Jakubowski, L, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BENOIT, FL | 2 |
| THEIL, GB | 1 |
| WATTEN, RH | 2 |
| Jakubowski, L | 1 |
| Luisetto, G | 1 |
| Mastrogiacomo, I | 1 |
| Bonanni, G | 1 |
| Pozzan, G | 1 |
| Botteon, S | 1 |
| Tizian, L | 1 |
| Galuppo, P | 1 |
| Horowitz, M | 1 |
| Wishart, JM | 1 |
| O'Loughlin, PD | 1 |
| Morris, HA | 1 |
| Need, AG | 1 |
| Nordin, BE | 1 |
| Drozdz, M | 1 |
| Kucharz, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skeletal Health of Klinefelter Patients is Not so Bad[NCT03704987] | 247 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydroxyproline and Klinefelter Syndrome
| Article | Year |
|---|---|
[Urinary excretion of hydroxyproline as an index of systemic collagen metabolism].
Topics: Adult; Age Factors; Body Surface Area; Bone and Bones; Bone Diseases; Bone Neoplasms; Calcinosis; Ch | 1972 |
5 other studies available for hydroxyproline and Klinefelter Syndrome
| Article | Year |
|---|---|
HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.
Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Anabolic Agents; Cushing Syndrome; | 1963 |
Urinary total hydroxyproline excretion in patients with Turner's syndrome and Klinefelter's syndrome.
Topics: Adolescent; Age Factors; Child; Chromosome Aberrations; Female; Humans; Hydroxyproline; Karyotyping; | 1981 |
Bone mass and mineral metabolism in Klinefelter's syndrome.
Topics: Adolescent; Adult; Bone Density; Creatinine; Femur; Gonadal Steroid Hormones; Humans; Hydroxyproline | 1995 |
Osteoporosis and Klinefelter's syndrome.
Topics: Adult; Aged; Body Composition; Bone Density; Creatinine; Dehydroepiandrosterone; Humans; Hydroxyprol | 1992 |
Renal tubular transport of hydroxyproline peptides: evidence for reabsorption and secretion.
Topics: Absorption; Acromegaly; Adult; Chromatography; Diet; Gelatin; Glomerular Filtration Rate; Humans; Hy | 1968 |