Page last updated: 2024-11-06

hydroxyproline and Kidney Stones

hydroxyproline has been researched along with Kidney Stones in 36 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis."5.33Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006)
"Hydroxyproline was determined under conditions of a very low proline diet and 1."5.26Urinary hydroxyproline concentration in primary hyperparathyroidism with and without renal stones. ( Sommer-Tsilenis, E, 1977)
" We used rats fed a high-fat diet (HFD) to achieve hyperlipidemia (HL) and hydroxyproline (HP) water to establish a hyperoxaluric CaOx nephrolithiasis model; the animals were administered statins (A) for 28 days."4.12Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet. ( Huang, HS; Liu, CJ; Tsai, YS, 2022)
"We previously reported hyperoxaluria and calcium oxalate calculi in adult pigs (sows) fed hydroxyproline (HP)."3.79Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model. ( Crenshaw, TD; Nakada, SY; Penniston, KL; Sehgal, PD; Sivalingam, S, 2013)
"Ethylene glycol (EG) exposure is a common model for kidney stones, because animals accumulate calcium oxalate monohydrate (COM) in kidneys."3.76Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity. ( Li, Y; McLaren, MC; McMartin, KE, 2010)
" Hyperoxaluria was induced by adding hydroxyproline (HP) to the drinking water."3.75Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains. ( Garrett, MR; Mandel, NS; Roman, RJ; Wiessner, JH, 2009)
"The provision of additional dietary hydroxyproline to GHS rats increases urinary oxalate excretion, calcium oxalate supersaturation and the ratio of calcium oxalate-to-calcium phosphate supersaturation, resulting in the formation of calcium oxalate kidney stones."3.71Calcium oxalate stone formation in genetic hypercalciuric stone-forming rats. ( Alexander, KM; Asplin, JR; Bushinsky, DA; Coe, FL; Evan, AP; Grynpas, MD; Parker, WR, 2002)
"HS did not affect the hyperoxaluria, hypocalciuria or supersaturation caused by HP; however, it increased calcium oxalate crystal deposition soon after 7 days of co-treatment."1.42High Sodium-Induced Oxidative Stress and Poor Anticrystallization Defense Aggravate Calcium Oxalate Crystal Formation in Rat Hyperoxaluric Kidneys. ( Huang, HS; Ma, MC, 2015)
"Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis."1.33Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006)
"Seventy patients with calcium nephrolithiasis and idiopathic hypercalciuria, 19 to 64 years old, were assessed for spine and femur mineral metabolism and bone density using a Dexa evaluation system."1.31Bone alterations in patients with idiopathic hypercalciuria and calcium nephrolithiasis. ( Bernardi, C; Cacciola, A; Ferrarese, P; Giannini, S; Ioverno, E; Nobile, M; Tasca, A; Visonà, E, 2002)
"Hydroxyproline was determined under conditions of a very low proline diet and 1."1.26Urinary hydroxyproline concentration in primary hyperparathyroidism with and without renal stones. ( Sommer-Tsilenis, E, 1977)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's4 (11.11)18.2507
2000's5 (13.89)29.6817
2010's4 (11.11)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Liu, CJ1
Tsai, YS1
Huang, HS2
Kumar, P1
Yang, Z1
Lever, JM1
Chávez, MD1
Fatima, H1
Crossman, DK1
Maynard, CL1
George, JF1
Mitchell, T1
Sivalingam, S1
Nakada, SY1
Sehgal, PD1
Crenshaw, TD1
Penniston, KL1
Khan, SR2
Joshi, S1
Wang, W1
Peck, AB1
Ma, MC1
Wiessner, JH1
Garrett, MR1
Roman, RJ1
Mandel, NS1
Li, Y1
McLaren, MC1
McMartin, KE1
Glenton, PA1
Byer, KJ1
Liu, J1
Cao, Z1
Zhang, Z1
Zhou, S1
Ye, Z1
de Vernejoul, MC1
Marie, P1
Kuntz, D1
Gueris, J1
Miravet, L1
Ryckewaert, A1
Tawashi, R3
Cousineau, M2
Sharkawi, M2
Ismail, SI1
Minisola, S1
Rosso, R1
Romagnoli, E1
Pacitti, MT1
Scarnecchia, L1
Carnevale, V1
Mazzuoli, G1
Messa, P2
Marangella, M1
Paganin, L1
Codardini, M1
Cruciatti, A1
Turrin, D1
Filiberto, Z1
Mioni, G1
Giannini, S2
Nobile, M2
Sartori, L1
Dalle Carbonare, L1
Ciuffreda, M1
Corrò, P1
D'Angelo, A2
Calò, L1
Crepaldi, G1
Bushinsky, DA1
Asplin, JR1
Grynpas, MD1
Evan, AP1
Parker, WR1
Alexander, KM1
Coe, FL1
Tasca, A1
Cacciola, A1
Ferrarese, P1
Ioverno, E1
Visonà, E1
Bernardi, C1
Kistler, H1
Nordin, BE2
Maschio, G1
Bonucci, E1
Pagano, F1
Ossi, E1
Lupo, A1
Valvo, E1
Tessitore, N1
Sommer-Tsilenis, E1
Van Kesteren, RG1
Van Heijst, AN1
Douze, JM1
Bank, JH1
Pikaar, SA1
Van der Most van Spijk, D1
Saro Gutiérrez, G1
Riancho Moral, JA1
Amado Señaris, JA1
Pracht Ferrer, C1
González Macías, J1
Sutton, RA1
Walker, VR1
Kiersztejn, M1
Kuczera, M1
Kokot, F1
Würth, JP1
Frielingsdorf, J1
Hammel, T1
Vetter, W1
Kageyama, S1
Hukushi, Y1
Metoki, R1
Kuwahara, M1
Orikasa, S1
Gallagher, JC1
Thomas, J4
Thomas, E3
Balan, L3
Guillon, JC1
Melon, JM2
Monsaingeon, A4
Adjiman, M1
Steg, A2
Aboulker, P2
Pak, CY1
Duburque, MT1
Savel, J1
Sauvel, G1
Sarragozi, P1
Benassayag, E1
Hockaday, TD1
Clayton, JE1
Smith, LH1
Horwith, M1
Buchanan, JR1
Gudmundsson, ST1
Mautalen, CA1

Reviews

3 reviews available for hydroxyproline and Kidney Stones

ArticleYear
[Primary hyperparthyroidism. Analysis of 152 patients with special reference to acute life threatening complications (acute hyperparathyroidism)].
    Schweizerische medizinische Wochenschrift. Supplementum, 1976, Issue:3

    Topics: Acute Disease; Adenoma; Adolescent; Adrenal Glands; Adult; Aged; Alkaline Phosphatase; Body Weight;

1976
Diagnostic procedures in disorders of calcium metabolism.
    Clinical endocrinology, 1978, Volume: 8, Issue:1

    Topics: Absorptiometry, Photon; Bone and Bones; Bone Resorption; Calcium; Calcium Metabolism Disorders; Crea

1978
Parathyroid hormone and thyrocalcitonin: their mode of action and regulation.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Adenoma; Adenylyl Cyclases; Adult; Animals; Biological Transport; Bone and Bones; Bone Resorption; C

1971

Other Studies

33 other studies available for hydroxyproline and Kidney Stones

ArticleYear
Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet.
    International journal of molecular sciences, 2022, Mar-11, Volume: 23, Issue:6

    Topics: Animals; Atorvastatin; Calcium; Calcium Oxalate; Diet, High-Fat; Hydroxymethylglutaryl-CoA Reductase

2022
Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 09-01, Volume: 1868, Issue:9

    Topics: Animals; Calcium Oxalate; Hydroxyproline; Inflammation; Kidney Calculi; Macrophages; Male; Nephrolit

2022
Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model.
    Journal of endourology, 2013, Volume: 27, Issue:12

    Topics: Animal Feed; Animals; Calcium Oxalate; Diet; Disease Models, Animal; Female; Hydroxyproline; Hyperox

2013
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.
    American journal of physiology. Renal physiology, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Acetophenones; Animals; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hyperoxal

2014
High Sodium-Induced Oxidative Stress and Poor Anticrystallization Defense Aggravate Calcium Oxalate Crystal Formation in Rat Hyperoxaluric Kidneys.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Animals; Antioxidants; Biomarkers; Calcium Oxalate; Citrates; Creatinine; Crystallization; Dicarboxy

2015
Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:2

    Topics: Animals; Animals, Congenic; Calcium Oxalate; Chromosomes, Mammalian; Disease Models, Animal; Genetic

2009
Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:3

    Topics: Animals; Calcium Oxalate; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylene Glycol;

2010
Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline.
    Kidney international, 2006, Volume: 70, Issue:5

    Topics: Animals; Calcium; Calcium Oxalate; Creatinine; Dinoprost; Disease Models, Animal; Gene Expression Re

2006
A comparative study on several models of experimental renal calcium oxalate stones formation in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2007, Volume: 27, Issue:1

    Topics: Ammonium Chloride; Animals; Blood Urea Nitrogen; Calcium; Calcium Gluconate; Calcium Oxalate; Creati

2007
Nonosteomalacic osteopathy associated with chronic hypophosphatemia.
    Calcified tissue international, 1982, Volume: 34, Issue:3

    Topics: Adult; Alkaline Phosphatase; Bone Diseases; Calcium; Creatinine; Humans; Hydroxyproline; Kidney Calc

1982
Effect of sodium copper chlorophyllin on the formation of calcium oxalate crystals in rat kidney.
    Investigative urology, 1980, Volume: 18, Issue:2

    Topics: Animals; Calcium Oxalate; Chlorophyll; Chlorophyllides; Crystallization; Hydroxyproline; Kidney Calc

1980
Size distribution characteristics of mineral phase in renal stones.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:7

    Topics: Animals; Calcium Oxalate; Calcium Phosphates; Hydroxyproline; Kidney Calculi; Magnesium; Magnesium C

1980
Calcium oxalate crystal formation in the kidneys of rats injected with 4-hydroxy-L-proline.
    Urological research, 1980, Volume: 8, Issue:2

    Topics: Animals; Calcium Oxalate; Crystallization; Hydroxyproline; Kidney Calculi; Male; Rats

1980
Trabecular bone mineral density in primary hyperparathyroidism: relationship to clinical presentation and biomarkers of skeletal turnover.
    Bone and mineral, 1993, Volume: 20, Issue:2

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Biomarkers; Bone Density; Calcium; Creatinine; Female;

1993
Different dietary calcium intake and relative supersaturation of calcium oxalate in the urine of patients forming renal stones.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:3

    Topics: Adult; Calcium; Calcium Oxalate; Calcium, Dietary; Citric Acid; Female; Humans; Hydroxyproline; Inte

1997
Acute effects of moderate dietary protein restriction in patients with idiopathic hypercalciuria and calcium nephrolithiasis.
    The American journal of clinical nutrition, 1999, Volume: 69, Issue:2

    Topics: Calcium; Citric Acid; Diet, Protein-Restricted; Dinoprostone; Female; Humans; Hydroxyproline; Kidney

1999
Calcium oxalate stone formation in genetic hypercalciuric stone-forming rats.
    Kidney international, 2002, Volume: 61, Issue:3

    Topics: Animals; Calcium; Calcium Oxalate; Calcium Phosphates; Diet; Diuresis; Hydrogen-Ion Concentration; H

2002
Bone alterations in patients with idiopathic hypercalciuria and calcium nephrolithiasis.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adult; Alkaline Phosphatase; Bone Density; Bone Resorption; Calcium; Calcium Metabolism Disorders; F

2002
Aspects of calcium metabolism in obstructive nephropathy: a metabolic and bone biopsy investigation.
    Nephron, 1977, Volume: 19, Issue:1

    Topics: Adult; Bone Resorption; Calcium; Chronic Kidney Disease-Mineral and Bone Disorder; Creatinine; Femal

1977
Urinary hydroxyproline concentration in primary hyperparathyroidism with and without renal stones.
    European urology, 1977, Volume: 3, Issue:4

    Topics: Adult; Alkaline Phosphatase; Calcium; Creatinine; Female; Humans; Hydroxyproline; Hyperparathyroidis

1977
[Tetanus and muscle relaxants].
    Nederlands tijdschrift voor geneeskunde, 1977, Nov-26, Volume: 121, Issue:48

    Topics: Calcium; Diazepam; Humans; Hydroxyproline; Kidney Calculi; Tetanus; Tubocurarine

1977
[Response of vitamin D metabolites to calcium restriction in hypercalciuric renal lithiasis].
    Medicina clinica, 1990, Mar-17, Volume: 94, Issue:10

    Topics: Adult; Calcium; Calcium, Dietary; Cyclic AMP; Female; Humans; Hydroxycholecalciferols; Hydroxyprolin

1990
Bone resorption and hypercalciuria in calcium stoneformers.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:6

    Topics: Adult; Bone Resorption; Calcium; Circadian Rhythm; Creatinine; Cyclic AMP; Fasting; Humans; Hydroxyp

1986
Selected biochemical parameters in patients with active nephrolithiasis.
    Acta medica Polona, 1986, Volume: 27, Issue:1-2

    Topics: Adult; Alkaline Phosphatase; Circadian Rhythm; Electrolytes; Female; Humans; Hydroxyproline; Kidney

1986
[Colic-like pain in the side].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Oct-07, Volume: 75, Issue:41

    Topics: Alkaline Phosphatase; Humans; Hydroxyproline; Kidney Calculi; Male; Middle Aged; Osteitis Deformans;

1986
[Microscopic and scanning electron microscopic study of intrarenal caluculogenesis. Intrarenal crystal distribution and movement in rats injected with L-hydroxyproline within short period].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1986, Volume: 77, Issue:8

    Topics: Animals; Calcium Oxalate; Crystallization; Hydroxyproline; Kidney; Kidney Calculi; Male; Microscopy,

1986
Treatment with with oestrogens of primary hyperparathyroidism in post-menopausal women.
    Lancet (London, England), 1972, Mar-04, Volume: 1, Issue:7749

    Topics: Bone Resorption; Calcium; Ethinyl Estradiol; Female; Humans; Hydroxyproline; Hyperparathyroidism; Ki

1972
[Experimental oxalic lithiasis induced by hydroxyproline].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1971, Volume: 165, Issue:2

    Topics: Animals; Calcium; Guinea Pigs; Hydroxyproline; Injections, Intraperitoneal; Kidney; Kidney Calculi;

1971
[Hyperparathyroidism and renal lithiasis. Biological diagnosis. Current exploration methods].
    Rein et foie, maladies de la nutrition; actualites, 1970, Volume: 13

    Topics: Aluminum; Calcium; Citrates; Edetic Acid; Humans; Hydroxyproline; Hyperparathyroidism; Kidney Calcul

1970
[Experimental oxalic lithiases in rats. Influence of certain Krebs cycle intermediates].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1973, Volume: 167, Issue:12

    Topics: Administration, Oral; Animals; Citrates; Citric Acid Cycle; Disease Models, Animal; Ethylene Glycols

1973
[Urinary elimination of hydroxyproline. Influence of the absorption of aluminium carbonate (1st results)].
    Journal d'urologie et de nephrologie, 1969, Volume: 75, Issue:12

    Topics: Aluminum; Antacids; Bone and Bones; Calcium; Carbonates; Collagen; Humans; Hydroxyproline; Kidney Ca

1969
The metabolic error in primary hyperoxaluria.
    Archives of disease in childhood, 1965, Volume: 40, Issue:213

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Carbon Isotopes; Family; Glycine; Glycolates; Glyo

1965
Primary hyperparathyroidism--evaluation of diagnostic aids: calcium infusion, phosphorus deprivation and hydroxyprolinuria.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:8

    Topics: Calcium; Diet; Humans; Hydroxyproline; Hyperparathyroidism; Kidney Calculi; Osteoporosis; Phosphates

1966