Page last updated: 2024-11-06

hydroxyproline and Kidney Diseases

hydroxyproline has been researched along with Kidney Diseases in 35 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"The simple postabsorptive urine hydroxyproline (Spot-HYPRO) with dialyzable and non-dialyzable (ND) fractions was measured in 28 patients with multiple myeloma."7.66The postabsorptive urinary hydroxyproline (spot-HYPRO) in patients with multiple myeloma. ( Neely, CL; Niell, HB; Palmieri, GM, 1981)
"Serum proline iminopeptidase and (where possible) urinary hydroxyproline were determined in 214 subjects: normal subjects, subjects with chronic kidney disease, subjects with chronic liver disease, subjects with osteitis deformans, subjects with rheumatoid arthritis, and subjects with osteoporosis."3.66[Rarefying osteopathy in rheumatology. Methods of evaluation and comparison of urinary hydroxyproline and serum proline iminopeptidase]. ( Carrozzo, M; D'Amore, M; Martiradonna, A; Quarto, S; Terlizzi, N, 1980)
"The simple postabsorptive urine hydroxyproline (Spot-HYPRO) with dialyzable and non-dialyzable (ND) fractions was measured in 28 patients with multiple myeloma."3.66The postabsorptive urinary hydroxyproline (spot-HYPRO) in patients with multiple myeloma. ( Neely, CL; Niell, HB; Palmieri, GM, 1981)
"The renal excretion of 3-hydroxyproline (3-HYP), an isomer of 4-hydroxyproline (4-HYP) found 6-10 times more in basement membrane collagen than in interstitial collagen, was investigated in control subjects and in 58 adult patients with various kidney diseases."3.66Urinary 3-hydroxyproline in renal disease. ( Birembaut, P; Borel, PJ; Brunois, JP; Chanard, J; Szymanowicz, A; Toupance, O, 1980)
"Betaine treatment significantly attenuated arsenic-induced decrease in renal eNOS expression."1.72Betaine attenuates sodium arsenite-induced renal dysfunction in rats. ( Kaur, T; Pathak, D; Sharma, AK; Sharma, S; Singh, AP; Singh, B; Yadav, HN, 2022)
"Kidney fibrosis is a common process that leads to the progression of various types of kidney disease."1.38A systems approach identifies HIPK2 as a key regulator of kidney fibrosis. ( Chen, EY; Chen, N; Chuang, PY; D'Agati, V; Dai, Y; Fan, Y; He, JC; Jin, Y; Ma'ayan, A; Mazloom, AR; Ratnam, K; Ross, MJ; Xiong, H; Zhong, Y, 2012)
" Clinical chemistry and histopathology indicated male rats were slightly more affected than female rats following dosing with the 120 and 180 ppm formulations; hydroxyproline excretion also supports this finding."1.38Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats. ( Beger, RD; Bhattacharyya, S; Gamboa da Costa, G; Pence, LM; Schnackenberg, LK; Sun, J, 2012)
"Fibrosis is a hallmark of progressive organ disease."1.34Blockade of IP-10/CXCR3 promotes progressive renal fibrosis. ( Furuichi, K; Gerard, C; Haino, M; Ishida, Y; Kaneko, S; Kawachi, H; Kitagawa, K; Kondo, T; Matsushima, K; Nakaya, I; Narumi, S; Sakai, N; Shimizu, F; Sugaya, T; Wada, T; Yokoyama, H, 2007)
"Alport's syndrome is characterised by morphological and structural changes of the renal basement membranes."1.28Urinary 3-hydroxyproline excretion in Alport's syndrome: a non-invasive screening test? ( Bartosch, B; Lubec, G; Popow, C; Vycudilik, W, 1991)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199020 (57.14)18.7374
1990's1 (2.86)18.2507
2000's3 (8.57)29.6817
2010's9 (25.71)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Han, L1
Zou, Y1
Yu, C1
Sharma, S1
Kaur, T1
Sharma, AK1
Singh, B1
Pathak, D1
Yadav, HN1
Singh, AP1
Ren, J1
Zhang, J1
Rudemiller, NP1
Griffiths, R1
Wen, Y1
Lu, X2
Privratsky, JR1
Gunn, MD1
Crowley, SD1
Sharma, A1
Hye Khan, MA1
Levick, SP1
Lee, KS1
Hammock, BD1
Imig, JD1
Fang, J1
Wang, W1
Sun, S1
Wang, Y1
Li, Q1
Qiu, M1
Zhang, Y2
Wang, QL1
Yuan, JL1
Tao, YY1
Liu, P1
Liu, CH1
Okumura, N1
Sudo, K1
Takao, T1
Nakanishi, T1
Morokata, T1
Noto, T1
Kubo, K1
Umeno, H1
Kinugasa, F1
Eikyu, Y1
Kozuki, Y1
Seki, N1
Schmaderer, C1
Xing, CJ1
Anderson, G1
Hermans, R1
Lutz, J1
Heemann, U1
Baumann, M1
Jin, Y1
Ratnam, K1
Chuang, PY1
Fan, Y1
Zhong, Y1
Dai, Y1
Mazloom, AR1
Chen, EY1
D'Agati, V1
Xiong, H1
Ross, MJ1
Chen, N1
Ma'ayan, A1
He, JC1
Schnackenberg, LK1
Sun, J1
Pence, LM1
Bhattacharyya, S1
Gamboa da Costa, G1
Beger, RD1
PERKOFF, GT1
Siddiqi, NJ1
Alhomida, AS1
Nakaya, I1
Wada, T1
Furuichi, K1
Sakai, N1
Kitagawa, K1
Yokoyama, H1
Ishida, Y1
Kondo, T1
Sugaya, T1
Kawachi, H1
Shimizu, F1
Narumi, S1
Haino, M1
Gerard, C1
Matsushima, K1
Kaneko, S1
Bruno, NE1
Yano, Y1
Takei, Y1
Gabazza, EC1
Qin, L1
Nagashima, M1
Morser, J1
D'Alessandro-Gabazza, CN1
Taguchi, O1
Sumida, Y1
Lisá, L1
Lacková, E1
Jansa, M1
Sivanova, LA1
Ananenko, AA1
Korovina, NA1
Abrosimova, NA1
Tănase-Mogoş, I1
Ciortoloman, H1
Petrescu, L1
Pâtea, P1
Popescu, M1
Ankăr, V1
Grigorescu, G1
D'Amore, M1
Quarto, S1
Terlizzi, N1
Martiradonna, A1
Carrozzo, M1
Chanard, J2
Szymanowicz, A2
Brunois, JP2
Toupance, O2
Melin, JP1
Birembaut, P2
Randoux, A1
Borel, PJ2
Niell, HB1
Neely, CL1
Palmieri, GM1
Michael, AF1
Brown, DM1
Man, M1
Nagle, RB1
Adams, E1
Hecht, A1
Gershberg, H1
St Paul, H1
Bartosch, B1
Vycudilik, W1
Popow, C1
Lubec, G1
Kozlowski, H1
Hrabowska, M1
Bank, H1
Crispin, M1
Ehrlich, D1
Szeinberg, A1
Kocher, P1
Simon, NM1
Bell, NH1
Del Greco, F1
Herting, W1
Liebegott, G1
Heller, H1
Miyakawa, T2
Berger, R1
Broyer, M1

Reviews

2 reviews available for hydroxyproline and Kidney Diseases

ArticleYear
[Urinary peptidomics].
    Nihon Jinzo Gakkai shi, 2010, Volume: 52, Issue:4

    Topics: Biomarkers; Chromatography, Liquid; Collagen; Humans; Hydroxyproline; Kidney Diseases; Peptides; Pro

2010
FAMILIAL ASPECTS OF DIFFUSE RENAL DISEASES.
    Annual review of medicine, 1964, Volume: 15

    Topics: Amyloidosis; Angiokeratoma; Blood; Congenital Abnormalities; Deafness; Genetics, Medical; Hematuria;

1964

Other Studies

33 other studies available for hydroxyproline and Kidney Diseases

ArticleYear
Targeting CC chemokine ligand (CCL) 20 by miR-143-5p alleviate lead poisoning-induced renal fibrosis by regulating interstitial fibroblasts excessive proliferation and dysfunction.
    Bioengineered, 2022, Volume: 13, Issue:4

    Topics: Animals; Cell Proliferation; Chemokines, CC; Female; Fibroblasts; Fibrosis; Humans; Hydroxyproline;

2022
Betaine attenuates sodium arsenite-induced renal dysfunction in rats.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Animals; Antioxidants; Arsenic; Arsenites; Betaine; Creatinine; Glutathione; Hydroxyproline; Kidney

2022
Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis
    Journal of the American Society of Nephrology : JASN, 2019, Volume: 30, Issue:9

    Topics: Actins; Animals; Benzofurans; Collagen Type I; CX3C Chemokine Receptor 1; Disease Models, Animal; Ex

2019
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.
    International journal of molecular sciences, 2016, May-18, Volume: 17, Issue:5

    Topics: Actins; Animals; Collagen; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fatty Acids, O

2016
Metabolomics study of renal fibrosis and intervention effects of total aglycone extracts of Scutellaria baicalensis in unilateral ureteral obstruction rats.
    Journal of ethnopharmacology, 2016, Nov-04, Volume: 192

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Discr

2016
Fuzheng Huayu recipe and vitamin E reverse renal interstitial fibrosis through counteracting TGF-beta1-induced epithelial-to-mesenchymal transition.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Benzamides; Biological Transport; Cadherins; Collagen

2010
Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on renal fibrosis in unilateral ureteral obstruction in rats.
    International immunopharmacology, 2010, Volume: 10, Issue:11

    Topics: Acridines; Animals; Chemokine CCL2; Chronic Disease; Collagen; Fibrosis; Hydroxyproline; IMP Dehydro

2010
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
    Life sciences, 2011, Sep-12, Volume: 89, Issue:11-12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Ag

2011
A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.
    Nature medicine, 2012, Mar-11, Volume: 18, Issue:4

    Topics: Analysis of Variance; Animals; Apoptosis; Carrier Proteins; Cell Differentiation; Cells, Cultured; C

2012
Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Animals; Biomarkers; Female; Fibrosis; Hydroxyproline; Kidney Diseases; Male; Metabolomics; Rats; Ra

2012
Effect of mercuric chloride on urinary excretion of free hydroxyproline.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Collagen; Creatinine; Dose-Response Relationship, Drug; H

2006
Blockade of IP-10/CXCR3 promotes progressive renal fibrosis.
    Nephron. Experimental nephrology, 2007, Volume: 107, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; Chemokine CXCL10; Chemokines, CXC; Disease Progres

2007
Protective role of thrombin activatable fibrinolysis inhibitor in obstructive nephropathy-associated tubulointerstitial fibrosis.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:1

    Topics: Animals; Carboxypeptidase B2; Cytokines; Fibrinolysin; Fibrosis; Hydroxyproline; Kidney Diseases; Ma

2008
[Hydroxyproline in children].
    Ceskoslovenska pediatrie, 1967, Volume: 22, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Growth; Humans; Hydroxyproline; Infant; Infant, Newborn; Kidney

1967
[Importance of studying oxyproline and glycosaminoglycans in skin fibroblast culture in the congenital and hereditary kidney diseases of children].
    Pediatriia, 1984, Issue:6

    Topics: Cells, Cultured; Child; Diagnosis, Differential; Fibroblasts; Glycosaminoglycans; Histocytochemistry

1984
[Metabolic errors of the cystinuria-lysinuria, cystinosis type detected in the newborn infant and child with renal and ocular diseases].
    Physiologie (Bucarest), 1981, Volume: 18, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cystinosis; Cystinuria; Eye Diseases; Female; Humans; Hydroxypr

1981
[Rarefying osteopathy in rheumatology. Methods of evaluation and comparison of urinary hydroxyproline and serum proline iminopeptidase].
    Minerva medica, 1980, Jul-31, Volume: 71, Issue:29

    Topics: Adult; Aged; Aminopeptidases; Arthritis, Rheumatoid; Bone Diseases; Female; Humans; Hydroxyproline;

1980
Increased renal excretion of 3 hydroxyproline in patients with active glomerular nephropathies and with polycystic renal disease.
    Clinical nephrology, 1982, Volume: 17, Issue:2

    Topics: Acute Kidney Injury; Adult; Glomerulonephritis; Humans; Hydroxyproline; Kidney Diseases; Nephritis,

1982
The postabsorptive urinary hydroxyproline (spot-HYPRO) in patients with multiple myeloma.
    Cancer, 1981, Aug-01, Volume: 48, Issue:3

    Topics: Bone Resorption; Creatinine; Dialysis; Follow-Up Studies; Humans; Hydroxyproline; Kidney Diseases; M

1981
Increased concentration of albumin in kidney basement membranes in diabetes mellitus.
    Diabetes, 1981, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Albumins; Basement Membrane; Child; Diabetic Nephropathies; Humans; Hydroxyprolin

1981
Urinary 3-hydroxyproline in renal disease.
    Renal physiology, 1980, Volume: 3, Issue:1-6

    Topics: Adolescent; Adult; Creatinine; Glomerulonephritis; Humans; Hydroxyproline; Infant; Kidney Diseases;

1980
Chemical estimation of interstitial and basement membrane collagen in obstructive nephropathy.
    Experimental and molecular pathology, 1978, Volume: 29, Issue:2

    Topics: Animals; Basement Membrane; Collagen; Hydroxyproline; Kidney Cortex; Kidney Diseases; Rabbits

1978
Primary hyperparathyroidism. Laboratory and clinical data in 73 cases.
    JAMA, 1975, Aug-11, Volume: 233, Issue:6

    Topics: Adenoma; Adolescent; Adult; Age Factors; Aged; Bone Diseases; Calcium; Depression; Female; Glomerula

1975
Urinary 3-hydroxyproline excretion in Alport's syndrome: a non-invasive screening test?
    Archives of disease in childhood, 1991, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chromatography, Thin Layer; Female; Humans;

1991
[Influence of DL-hydroxyproline on the development of experimental amyloidosis].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1972, Volume: 116, Issue:1

    Topics: Amyloid; Amyloidosis; Animals; Caseins; Cytoplasm; Female; Hydroxyproline; Hyperplasia; Injections,

1972
Iminoglycinuria. A defect of renal tubular transport.
    Israel journal of medical sciences, 1972, Volume: 81, Issue:5

    Topics: Adult; Amino Acids; Chromatography, Paper; Feces; Glycine; Humans; Hydroxyproline; Imines; Kidney Di

1972
[Study of urinary hydroxyproline in osteopathies].
    Pathologie et biologie, 1966, Volume: 14, Issue:21

    Topics: Acromegaly; Adult; Aged; Bone Neoplasms; Female; Humans; Hydroxyproline; Hyperparathyroidism; Hypert

1966
Iminoacidopathy in renal failure.
    Archives of internal medicine, 1970, Volume: 125, Issue:2

    Topics: Calcium; Glycine; Humans; Hydroxyproline; Hyperparathyroidism, Secondary; Kidney Diseases; Kidney Fa

1970
[Congenital familial osteopetrosis (marble bone disease Albers-Schönberg). A contribution to the pathogenesis].
    Beitrage zur Pathologie, 1971, Volume: 143, Issue:2

    Topics: Albuminuria; Amino Acids; Anemia; Autopsy; Bone and Bones; Female; Goiter; Humans; Hydroxyproline; H

1971
[Congenital phophaturia, its causes and consequences].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Mar-15, Volume: 22, Issue:6

    Topics: Adolescent; Alkaline Phosphatase; Blood Sedimentation; Bone Diseases; Humans; Hydroxyproline; Kidney

1967
Studies on the alterations in glucosamine, galactosamine and hydroxyproline contents of the kidney, liver, serum and urine in experimental renal disease.
    Acta medica et biologica, 1968, Volume: 15, Issue:3

    Topics: Animals; Chromatography; Glucosamine; Hexosamines; Hydroxyproline; Kidney; Kidney Diseases; Liver; R

1968
[Hyperprolinemia and hydroxyprolinemia].
    La Presse medicale, 1969, May-28, Volume: 77, Issue:26

    Topics: Amino Acid Metabolism, Inborn Errors; Child; Collagen; Consanguinity; Female; Genes, Recessive; Glyc

1969
[Studies on the alterations in glucosamine, galactosamine and hydroxyproline contents of kidney, liver, serum and urine in experimental renal disease].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1965, May-10, Volume: 54, Issue:2

    Topics: Animals; Blood; Galactose; Glucosamine; Hydroxyproline; Kidney; Kidney Diseases; Liver; Urine

1965