Page last updated: 2024-11-06

hydroxyproline and Ischemia

hydroxyproline has been researched along with Ischemia in 19 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Genistein is a natural isoflavonoid and has several pharmacological effects, such as antioxidant, antitumor activity, and improvement of glucose metabolism."5.72The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury. ( Akıncı, O; Kepil, N; Tosun, Y, 2022)
" Collagen excess was obtained in 10 rats with unilateral renal ischemia for 5 wk followed by 3-wk treatment with ramipril (20 mg."3.70Alterations in myocardial collagen content affect rat papillary muscle function. ( Cicogna, AC; Janicki, JS; Matsubara, BB; Matsubara, LS; Okoshi, MP, 2000)
"Genistein is a natural isoflavonoid and has several pharmacological effects, such as antioxidant, antitumor activity, and improvement of glucose metabolism."1.72The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury. ( Akıncı, O; Kepil, N; Tosun, Y, 2022)
"Ischemia was induced in rats by clamping both the superior mesenteric artery and ileal branches for 30 min."1.35Early anastomotic repair in the rat intestine is affected by transient preoperative mesenteric ischemia. ( Bleichrodt, RP; de Man, BM; Hendriks, T; Lomme, RM; Posma, LA; van Goor, H, 2009)
"Hydroxyproline and histology were not different between groups."1.34A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat. ( Bleichrodt, RP; Hendriks, T; Posma, LA; van Goor, H, 2007)
"The hydroxyproline levels in all treated groups were different from the control group significantly (P<0."1.33Effects of hyperbaric oxygen and Pgg-glucan on ischemic colon anastomosis. ( AS, A; Atukeren, P; Celik, V; Ferahman, M; Gazioglu, E; Guzel, S; Mutlu, O; Nuri, MM; Sunamak, O, 2006)
"Hydroxyproline content was increased 75% with allopurinol and 113% with SOD in the wound by day 7 (p < 0."1.30Oxygen free radicals impair wound healing in ischemic rat skin. ( Ahçioğlu, F; Bulan, R; Cetinkale, O; Ozbay, G; Senel, O, 1997)
"Digitoxin treatment did not alter peak flow velocity or flow acceleration, but did significantly increase isovolumic (dP/dt)P-1."1.26Effect of prophylactic digitalization on the development of myocardial hypertrophy. ( Arcilla, RA; Cutilletta, AF; Rudnik, M; Straube, R, 1977)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's3 (15.79)18.2507
2000's6 (31.58)29.6817
2010's5 (26.32)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Akıncı, O1
Tosun, Y1
Kepil, N1
Kayapınar, AK1
Ercan, M1
Baş, KK1
Yamak, S1
Erçin, U1
Türkoğlu, MA1
Bostancı, EB1
Portilla-de Buen, E1
Orozco-Mosqueda, A1
Leal-Cortés, C1
Vázquez-Camacho, G1
Fuentes-Orozco, C1
Alvarez-Villaseñor, AS1
Macías-Amezcua, MD1
González-Ojeda, A1
Gündoğdu, RH1
Temel, H1
Bozkırlı, BO1
Ersoy, E1
Yazgan, A1
Yıldırım, Z1
Emir, S1
Gurdal, SO1
Sozen, S1
Bali, I1
Yesildag, E1
Celik, A1
Guzel, S2
Sahin, O1
Ay, H1
Topcu, B1
Şenocak, R1
Özer, MT1
Kaymak, Ş1
Kılbaş, Z1
Günal, A1
Uyanık, M1
Kozak, O1
Posma, LA2
Bleichrodt, RP2
Lomme, RM1
de Man, BM1
van Goor, H2
Hendriks, T2
Georgii, JL1
Amadeu, TP1
Seabra, AB1
de Oliveira, MG1
Monte-Alto-Costa, A1
Buemi, M1
Galeano, M1
Sturiale, A1
Ientile, R1
Crisafulli, C1
Parisi, A1
Catania, M1
Calapai, G1
Impalà, P1
Aloisi, C1
Squadrito, F1
Altavilla, D1
Bitto, A1
Tuccari, G1
Frisina, N1
Sunamak, O1
AS, A1
Celik, V1
Ferahman, M1
Nuri, MM1
Gazioglu, E1
Atukeren, P1
Mutlu, O1
Colak, T1
Turkmenoglu, O1
Dag, A1
Polat, A1
Comelekoglu, U1
Bagdatoglu, O1
Polat, G1
Kanik, A1
Akca, T1
Aydin, S2
Evans, DM1
McAree, K1
Guyton, DP1
Hawkins, N1
Stakleff, K1
Senel, O1
Cetinkale, O1
Ozbay, G1
Ahçioğlu, F1
Bulan, R1
Hamzaoğlu, I1
Karahasanoğlu, T1
Sahin, DA1
Carkman, S1
Sariyar, M1
Alemdaroğlu, K1
Matsubara, LS1
Matsubara, BB1
Okoshi, MP1
Cicogna, AC1
Janicki, JS1
Cutilletta, AF1
Rudnik, M1
Arcilla, RA1
Straube, R1
Foster, ME1
Brennan, SS1
Morgan, A1
Leaper, DJ1
Leon, AS1
White, FC1
Bloor, CM1
Saviano, MA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Supplementation With b- Hydroxy Methyl Butyrate and Glutamine in Wound Healing Histology in Type 2 Diabetes and Controls Bloody Areas[NCT03782155]Phase 430 participants (Anticipated)Interventional2021-06-01Not yet recruiting
''Erythropoietin Gel as an Adjunct to Split-Thickness Apically Positioned Flap in Augmentation of Attached Gingiva'' (A Randomized Controlled Clinical Study)[NCT05683782]Phase 420 participants (Anticipated)Interventional2022-10-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

19 other studies available for hydroxyproline and Ischemia

ArticleYear
The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury.
    The Journal of surgical research, 2022, Volume: 280

    Topics: Anastomosis, Surgical; Animals; Antioxidants; Colon; Genistein; Glucose; Glutathione Peroxidase; Hyd

2022
The effect of carbon monoxide releasing molecule-2 (CORM-2) on healing of ischemic colon anastomosis in rats
    Turkish journal of medical sciences, 2021, 08-30, Volume: 51, Issue:4

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Carbon Monoxide; Colon; Glutathione; Hydroxyprolin

2021
Fibrinogen and thrombin concentrations are critical for fibrin glue adherence in rat high-risk colon anastomoses.
    Clinics (Sao Paulo, Brazil), 2014, Volume: 69, Issue:4

    Topics: Anastomosis, Surgical; Animals; Collagen; Colon; Female; Fibrin Tissue Adhesive; Fibrinogen; Hydroxy

2014
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
    JPEN. Journal of parenteral and enteral nutrition, 2017, Volume: 41, Issue:6

    Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats

2017
Does hyperbaric oxygen therapy reduce the effects of ischemia on colonic anastomosis in laparoscopic colon resection?
    Annali italiani di chirurgia, 2016, Volume: 87

    Topics: Anastomosis, Surgical; Animals; Cell Division; Colon; Fibroblasts; Hydroxyproline; Hyperbaric Oxygen

2016
Can Human Recombinant Epidermal Growth Factor Improve Ischemia and Induce Healing of Anastomosis in an Experimental Study in a Rabbit Model?
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2017, Volume: 30, Issue:2

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Collagen; EGF Family of Proteins; Humans; Hydroxyp

2017
Early anastomotic repair in the rat intestine is affected by transient preoperative mesenteric ischemia.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:6

    Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Colon; Gelatinases; Hydroxyproline; Ileum; Isc

2009
Topical S-nitrosoglutathione-releasing hydrogel improves healing of rat ischaemic wounds.
    Journal of tissue engineering and regenerative medicine, 2011, Volume: 5, Issue:8

    Topics: Administration, Topical; Animals; Cell Degranulation; Granulation Tissue; Hydrogel, Polyethylene Gly

2011
Recombinant human erythropoietin stimulates angiogenesis and healing of ischemic skin wounds.
    Shock (Augusta, Ga.), 2004, Volume: 22, Issue:2

    Topics: Animals; Collagen; Erythrocytes; Erythropoietin; Hemoglobins; Humans; Hydroxyproline; Immunohistoche

2004
Effects of hyperbaric oxygen and Pgg-glucan on ischemic colon anastomosis.
    World journal of gastroenterology, 2006, Mar-07, Volume: 12, Issue:9

    Topics: Anastomosis, Surgical; Animals; beta-Glucans; Colon; Combined Modality Therapy; Female; Hydroxyproli

2006
A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat.
    International journal of colorectal disease, 2007, Volume: 22, Issue:12

    Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Ileum; Ischemia; Male

2007
The effect of remote ischemic preconditioning on healing of colonic anastomoses.
    The Journal of surgical research, 2007, Volume: 143, Issue:2

    Topics: Anastomosis, Surgical; Animals; Arterial Occlusive Diseases; Colon; Hydroxyproline; Ischemia; Ischem

2007
Dose dependency and wound healing aspects of the use of tissue plasminogen activator in the prevention of intra-abdominal adhesions.
    American journal of surgery, 1993, Volume: 165, Issue:2

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Ischemia; Ligatio

1993
Oxygen free radicals impair wound healing in ischemic rat skin.
    Annals of plastic surgery, 1997, Volume: 39, Issue:5

    Topics: Allopurinol; Animals; Body Water; Collagen; Free Radicals; Hydroxyproline; Ischemia; Rats; Rats, Wis

1997
The effects of hyperbaric oxygen on normal and ischemic colon anastomoses.
    American journal of surgery, 1998, Volume: 176, Issue:5

    Topics: Anastomosis, Surgical; Animals; Colon; Hydroxyproline; Hyperbaric Oxygenation; Ischemia; Male; Posto

1998
Alterations in myocardial collagen content affect rat papillary muscle function.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Elasticity; Glutathione Disulfide; Hydr

2000
Effect of prophylactic digitalization on the development of myocardial hypertrophy.
    The American journal of physiology, 1977, Volume: 233, Issue:5

    Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Coronary Circulation; Digitoxin; Female; Hea

1977
Colonic ischaemia and anastomotic healing.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1985, Volume: 17, Issue:3

    Topics: Animals; Colon; Female; Hydroxyproline; Ischemia; Isoxsuprine; Pressure; Rats; Rats, Inbred Strains;

1985
Reduced myocardial fibrosis after dimethylsulfoxide (DMSO) treatment of isoproterenol-induced myocardial necrosis in rats.
    The American journal of the medical sciences, 1971, Volume: 261, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Heart Diseases; Hexosamines; Hydroxyproline; Ischemia; Isoproterenol; M

1971