hydroxyproline has been researched along with Intellectual Disability in 21 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyproline is a major constituent of collagen." | 1.30 | Hydroxyprolinemia: comparison of a patient and her unaffected twin sister. ( Kim, SZ; Levy, HL; Varvogli, L; Waisbren, SE, 1997) |
| "Hydroxyproline metabolism was evaluated in two sisters with hydroxyprolinemia and their mother." | 1.26 | Hydroxyproline metabolism in two sisters with hydroxyprolinemia. ( Blankenship, PR; Coryell, ME; Hall, WK; Lynch, WR; Roesel, RA; Thevaos, TG, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (85.71) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EFRON, ML | 2 |
| YOUNG, D | 1 |
| MOSER, HW | 1 |
| MACCREADY, RA | 1 |
| BIXBY, EM | 1 |
| PRYLES, CV | 1 |
| Iavanainen, M | 1 |
| Laitinen, O | 1 |
| Palo, J | 1 |
| Näntö-Salonen, K | 1 |
| Autio, S | 1 |
| Härö, E | 1 |
| Kivimäki, T | 1 |
| Koskela, SL | 1 |
| Näntö, V | 1 |
| Penttinen, R | 1 |
| Lejeune, J | 1 |
| Takahashi, M | 1 |
| Nagao, H | 1 |
| Matsuda, H | 1 |
| Kim, SZ | 1 |
| Varvogli, L | 1 |
| Waisbren, SE | 1 |
| Levy, HL | 1 |
| Roesel, RA | 1 |
| Blankenship, PR | 1 |
| Lynch, WR | 1 |
| Coryell, ME | 1 |
| Thevaos, TG | 1 |
| Hall, WK | 1 |
| Law, EA | 1 |
| Sardharwalla, IB | 1 |
| Statter, M | 1 |
| Ben-Zvi, A | 1 |
| Shina, A | 1 |
| Schein, R | 1 |
| Russell, A | 1 |
| Foldes, J | 1 |
| Balena, R | 1 |
| Ho, A | 1 |
| Parfitt, AM | 1 |
| Kleerekoper, M | 1 |
| Goodman, SI | 1 |
| Browder, JA | 1 |
| Winick, M | 1 |
| Brasel, JA | 1 |
| Velasco, E | 1 |
| Rosso, P | 1 |
| Krieger, I | 1 |
| Hart, ZH | 1 |
| Menne, F | 1 |
| Emery, FA | 1 |
| Goldie, L | 1 |
| Stern, J | 1 |
| Harris, LS | 1 |
| Gitter, KA | 1 |
| Galin, MA | 1 |
| Plechaty, GP | 1 |
| Prockop, DJ | 1 |
| Rosenberg, LE | 1 |
| Durant, JL | 1 |
| Elsas, LJ | 1 |
| Rokkones, T | 1 |
| Loken, AC | 1 |
| Berger, R | 1 |
| Broyer, M | 1 |
1 review available for hydroxyproline and Intellectual Disability
| Article | Year |
|---|---|
[Feeble mindedness caused by genetic disorders of amino acid metabolism].
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Glycine; Hartnup Disease; Histi | 1968 |
20 other studies available for hydroxyproline and Intellectual Disability
| Article | Year |
|---|---|
A SIMPLE CHROMATOGRAPHIC SCREENING TEST FOR THE DETECTION OF DISORDERS OF AMINO ACID METABOLISM. A TECHNIC USING WHOLE BLOOD OR URINE COLLECTED ON FILTER PAPER.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood Chemical Analysis; Chromatography; Citrulli | 1964 |
HYDROXYPROLINEMIA. II. A RARE METABOLIC DISEASE DUE TO A DEFICIENCY OF THE ENZYME "HYDROXYPROLINE OXIDASE".
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Blood; Blood Chemical | 1965 |
Diagnostic criteria in Marfan's disease.
Topics: Adolescent; Adult; Cardiomyopathies; Child; Child, Preschool; Consanguinity; Eye Diseases; Female; H | 1967 |
Metabolism of collagen in aspartylglycosaminuria: urinary excretion of hydroxyproline.
Topics: Acetylglucosamine; Adolescent; Adult; Age Factors; Child; Child, Preschool; Collagen; Connective Tis | 1984 |
[Fragile site Xq27 and metabolism of monocarbons].
Topics: Amino Acids; Aminolevulinic Acid; Female; Formyltetrahydrofolates; Humans; Hydroxyproline; Intellect | 1980 |
Estimating bone change in patients with severe disability.
Topics: Alkaline Phosphatase; Anticonvulsants; Bone Density; Bone Diseases; Calcium; Epilepsy; Glycosaminogl | 1995 |
Hydroxyprolinemia: comparison of a patient and her unaffected twin sister.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Diseases in Twins; Female; Humans; Hydroxyproline; Inte | 1997 |
Hydroxyproline metabolism in two sisters with hydroxyprolinemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Female; Glycolates; Humans; Hydroxyproline; Intellectua | 1979 |
A new type of heterozygote of familial renal iminoglycinuria.
Topics: Female; Genetic Carrier Screening; Glycine; Humans; Hydroxyproline; Intellectual Disability; Male; M | 1978 |
Familial iminoglycinuria with normal intestinal absorption of glycine and imino acids in association with profound mental retardation, a possible "cerebral phenotype".
Topics: Amino Acid Metabolism, Inborn Errors; Female; Glycine; Humans; Hydroxyproline; Imino Acids; Infant; | 1976 |
Hypophosphatemic rickets with hypocalciuria following long-term treatment with aluminum-containing antacid.
Topics: Adolescent; Aluminum Hydroxide; Antacids; Calcitriol; Calcium; Drug Administration Schedule; Drug Co | 1991 |
Hydroxylysinuria in association with trisomy 21.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child, Preschool; Chromatography, Paper; Collagen | 1970 |
Effects of early nutrition on growth of the central nervous system.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Animals; Brain; Brain Chemistry; Central Nervo | 1974 |
Valine-sensitive nonketotic hyperglycinemia. Case report.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Benzoates; Brain Diseases; Brain Stem; C | 1974 |
Hyperprolinaemia type 2.
Topics: Adolescent; Chromatography, Paper; Electroencephalography; Epilepsy, Absence; Female; Glycine; Human | 1968 |
Oculo-cerebro-renal syndrome. Report of a case in a baby girl.
Topics: Ammonia; Cataract; Female; Glaucoma; Growth Disorders; Humans; Hydroxyproline; Infant; Infant, Newbo | 1970 |
Hydroxyprolinemia as an illustration of nonessential enzymes in man.
Topics: Amino Acid Metabolism, Inborn Errors; Collagen; Humans; Hydroxyproline; Intellectual Disability; Pep | 1970 |
Familial iminoglycinuria. An inborn error of renal tubular transport.
Topics: Adult; Child; Chromosome Aberrations; Chromosome Disorders; Deafness; Female; Genotype; Glycine; Het | 1968 |
Congenital renal dysplasia, retinal dysplasia and mental retardation associated with hyperprolinuria and hyper-oh-prolinuria.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Female; Genetic Diseases, Inborn; Hu | 1968 |
[Hyperprolinemia and hydroxyprolinemia].
Topics: Amino Acid Metabolism, Inborn Errors; Child; Collagen; Consanguinity; Female; Genes, Recessive; Glyc | 1969 |