hydroxyproline has been researched along with Innate Inflammatory Response in 144 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It can promote PU alleviation and hydroxyproline secretion in the wound and inhibit pain and inflammatory reactions, which is worthy of clinical promotion." | 8.12 | Efficacy of Human-Recombinant Epidermal Growth Factor Combined with Povidone-Iodine for Pressure Ulcers and Its Influence on Inflammatory Cytokines. ( Lv, D; Wang, X; Yong, L; Zhang, B; Zhang, R; Zhao, Z, 2022) |
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 7.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| " NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression." | 7.77 | Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 7.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " Intratracheal bleomycin administration resulted in pulmonary fibrosis 14 and 21 days posttreatment, as evidenced by increased hydroxyproline content in bleomycin group (255." | 7.76 | Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. ( Chang, Q; Chen, X; Guo, Q; Huang, Y; Wang, J; Wang, W; Wang, X; Xu, J; Zhang, S; Zhao, L, 2010) |
| " Imiquimod, a synthetic Toll-like receptor (TLR) 7 ligand, has been shown to attenuate airway inflammation and airway hyperresponsiveness (AHR) in acute murine models of allergic asthma." | 7.75 | Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma. ( Chen, Z; Du, Q; Gu, XY; Huang, M; Yin, KS; Zhou, LF, 2009) |
| "A murine model of allergen-induced airway inflammation was used to examine the effects of exposure to ozone on airway inflammation and remodeling." | 7.72 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ozone. ( Kenyon, NJ; Last, JA; Temple, L; Ward, R, 2004) |
| "Liver fibrosis was induced in rats both with carbon tetrachloride and dimethylnitrosamine." | 7.68 | Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop ( Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E, 1992) |
| "Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis." | 5.40 | Ameliorative effect of mepenzolate bromide against pulmonary fibrosis. ( Asano, T; Azuma, A; Kurotsu, S; Mizushima, T; Niino, T; Sugizaki, T; Suzuki, H; Tanaka, K, 2014) |
| "Lung inflammation was measured by quantitative differential evaluation of lung lavage cells." | 5.32 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. ( Kenyon, NJ; Last, JA; Pinkerton, KE; Temple, L; Ward, R, 2004) |
| " Urothelial degeneration, necrosis, ulcer, bleeding, edema, inflammation and mast cell count, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), myeloperoxidase (MPO), and hydroxyproline parameters were evaluated." | 4.31 | Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model. ( Abdullah, A; Çiğdem, Y; Erhan, A; Tuğrul, EE, 2023) |
| " Inflammation and fibrosis were evaluated by transaminases, myeloperoxidase activity, hydroxyproline, and histological evaluation." | 4.12 | Chronic intermittent hypoxia promotes early intrahepatic endothelial impairment in rats with nonalcoholic fatty liver disease. ( Abrante, B; Abreu-González, P; de la Barreda, R; Díaz-Flores, F; González-Paredes, FJ; Hernández-Bustabad, A; Hernández-Guerra, M; Morales-Arraez, D; Quintero, E, 2022) |
| " It can promote PU alleviation and hydroxyproline secretion in the wound and inhibit pain and inflammatory reactions, which is worthy of clinical promotion." | 4.12 | Efficacy of Human-Recombinant Epidermal Growth Factor Combined with Povidone-Iodine for Pressure Ulcers and Its Influence on Inflammatory Cytokines. ( Lv, D; Wang, X; Yong, L; Zhang, B; Zhang, R; Zhao, Z, 2022) |
| " After observing the pulmonary function indexes of the rats on the 3rd, 7th and 14th days after modeling, the rats were sacrificed by cervical dislocation, the pulmonary inflammation and fibrosis of the rats were observed, and the HYP (hydroxyproline) content and miR-223 expression level were determined." | 3.96 | Expression and significance of miR-223 in rats with pulmonary fibrosis. ( Ju, P; Li, YM; Qu, SJ; Shen, WP; Song, ZZ; Zhao, L, 2020) |
| "SMT significantly reduced GAGs, hydroxyproline, matrix metalloproteinase (MMP)-13, tumour necrosis factor alpha (TNF-α), prostaglindin E2 (PGE2 ) and nitrite release in stimulated rabbit cartilage media indicating chondroprotective and anti-inflammatory effects of SMT in osteoarthritis (OA)." | 3.80 | Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis. ( Balaganur, V; Kumar, D; Kumari, RR; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK, 2014) |
| "To study the potential of high-dose N-acetylcysteine (NAC) to attenuate silica-induced pulmonary fibrosis in the rat." | 3.79 | High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat. ( Jiang, H; Yin, G; Zhang, C; Zhang, H, 2013) |
| " Blocking oxidative stress with N-acetylcysteine attenuated whole lung inflammation but had no effect on total lung hydroxyproline." | 3.78 | Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice. ( Auten, RL; Brass, DM; Dunkel, MK; Fattman, CL; Hollingsworth, JW; Latoche, JD; Li, Z; Potts-Kant, E; Reilly, SM; Spencer, JC, 2012) |
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 3.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| " NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression." | 3.77 | Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 3.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " Intratracheal bleomycin administration resulted in pulmonary fibrosis 14 and 21 days posttreatment, as evidenced by increased hydroxyproline content in bleomycin group (255." | 3.76 | Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. ( Chang, Q; Chen, X; Guo, Q; Huang, Y; Wang, J; Wang, W; Wang, X; Xu, J; Zhang, S; Zhao, L, 2010) |
| "6 g/kg bw) significantly reduced the serum levels of alanine aminotransferase and aspartate aminotransferase in rats treated with CCl4, and also decreased the thiobarbituric acid reactive substances, hydroxyproline and excessive inflammation in the livers of CCl4-treated rats." | 3.76 | Hepatoprotection by freshwater clam extract against CCl4-induced hepatic damage in rats. ( Hsu, CC; Hsu, CL; Yen, GC, 2010) |
| " Imiquimod, a synthetic Toll-like receptor (TLR) 7 ligand, has been shown to attenuate airway inflammation and airway hyperresponsiveness (AHR) in acute murine models of allergic asthma." | 3.75 | Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma. ( Chen, Z; Du, Q; Gu, XY; Huang, M; Yin, KS; Zhou, LF, 2009) |
| "A murine model of allergen-induced airway inflammation was used to examine the effects of exposure to ozone on airway inflammation and remodeling." | 3.72 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ozone. ( Kenyon, NJ; Last, JA; Temple, L; Ward, R, 2004) |
| "Although arginine plays an important role in many aspects of inflammation and wound healing, the mechanism is not clear." | 3.71 | The role of L-arginine and neutrophils on incisional wound healing. ( Cantürk, NZ; Cantürk, Z; Esen, N; Kirkal, G; Solakoglu, S; Vural, B; Vural, S, 2001) |
| "Liver fibrosis was induced in rats both with carbon tetrachloride and dimethylnitrosamine." | 3.68 | Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop ( Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E, 1992) |
| "Cristobalite is a crystalline silicon dioxide that elicits pulmonary inflammation and fibrosis in humans and experimental animals." | 3.67 | Biphasic cellular and tissue response of rat lungs after eight-day aerosol exposure to the silicon dioxide cristobalite. ( Absher, MP; Hemenway, DR; Leslie, KO; Mickey, RM; Trombley, L, 1989) |
| " Biological criteria becomes more and more useful to judge efficiency of the drugs which possess no or very little effect on acute phase of inflammation: inflammatory blood tests, urinary excretion of hydroxyproline and immunological analysis such as quantitative determinations of immuno-globulins and rheumatoid factors and lymphocytic functional tests." | 3.65 | Clinical and biochemical assessment of anti-inflammatory substances. ( Franchimont, P, 1976) |
| "Asthma is an inflammatory disease of airways, and the main trigger of asthma is allergic inflammation." | 1.72 | Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects. ( Athari, SS; Li, M; Li, Y; Wang, B; Wang, J; Wang, R, 2022) |
| "Pirfenidone is an FDA-approved anti-fibrotic drug for systemic use in the treatment of idiopathic lung fibrosis and other fibrotic disorders." | 1.51 | Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses. ( Dorati, R; Fourcaudot, AB; Leung, KP; Medina, JL; Sebastian, EA, 2019) |
| "Pretreatment with tadalafil protected against TAA-induced liver fibrosis, in a dose-dependent manner, as proved by the alleviation of inflammatory and fibrotic biomarkers." | 1.48 | The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats. ( Abdel-Salam, RM; Ahmed, NA; Mansour, HM; Salama, AAA; Yassen, NN; Zaki, HF, 2018) |
| "Intestinal fibrosis is thought to be a consequence of excessive tissue repair, and constitutes a common problem in patients with Crohn's disease (CD)." | 1.48 | Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis. ( Fagagnini, S; Hausmann, M; Hünerwadel, A; Jaeger, SU; Lutz, C; Mamie, C; Rogler, G; Ruiz, PA; Weder, B, 2018) |
| "Pulmonary fibrosis is a multifaceted disease with high mortality and morbidity, and it is commonly nonresponsive to conventional therapy." | 1.48 | Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats. ( Ahad, A; Ahmad Ansari, M; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Ali, N; Khan, A; Raish, M, 2018) |
| "Pulmonary fibrosis is a progressive lung disease that its pathogenic mechanism currently is incompletely understood." | 1.46 | Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary fibrosis mice. ( Dong, J; Han, F; Li, F; Li, H; Liu, X; Luo, M; Qiao, X; Shi, J; Wei, J; Yang, L; Zhang, J, 2017) |
| "Diastolic heart failure was established in 8-10 week old cardiomyocyte specific, inducible SERCA2a knock out (i." | 1.42 | Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice. ( Ahmed, MS; Alfsnes, K; Aronsen, JM; Attramadal, H; Aukrust, P; Christensen, G; Dhondup, Y; Gullestad, L; Haugstad, SB; Holmen, SD; Ranheim, T; Sandanger, Ø; Scott, H; Sjaastad, I; Vinge, LE; Yndestad, A; Zhang, L, 2015) |
| "Ipragliflozin is a selective sodium glucose cotransporter 2 (SGLT2) inhibitor that increases urinary glucose excretion by inhibiting renal glucose reabsorption and thereby causes a subsequent antihyperglycemic effect." | 1.42 | Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats. ( Hayashizaki-Someya, Y; Koide, K; Kurosaki, E; Mitori, H; Takakura, S; Takasu, T; Yamazaki, S, 2015) |
| "Idiopathic pulmonary fibrosis is a progressive fatal lung disease characterized by excessive collagen deposition, with no effective treatments." | 1.40 | Passion fruit peel extract attenuates bleomycin-induced pulmonary fibrosis in mice. ( Chilakapati, DR; Chilakapati, SR; Manikonda, PK; Serasanambati, M; Watson, RR, 2014) |
| "Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis." | 1.40 | Ameliorative effect of mepenzolate bromide against pulmonary fibrosis. ( Asano, T; Azuma, A; Kurotsu, S; Mizushima, T; Niino, T; Sugizaki, T; Suzuki, H; Tanaka, K, 2014) |
| "Idiopathic pulmonary fibrosis is a progressive and lethal disease, characterized by loss of lung elasticity and alveolar surface area, secondary to alveolar epithelial cell injury, reactive inflammation, proliferation of fibroblasts, and deposition of extracellular matrix." | 1.40 | Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230. ( Accart, N; Beckmann, N; Cannet, C; Dunbar, A; Egger, C; Gérard, C; Jarai, G; Jarman, E; Piaia, A; Schmid, HA; Tigani, B; Vidotto, N, 2014) |
| "Tendinopathy is a pathology found mainly in the rotator cuff, patellar, Achilles and flexor tendons." | 1.39 | Inflammatory process induced by carrageenan in adjacent tissue triggers the acute inflammation in deep digital flexor tendon of rats. ( Da Ré Guerra, F; De Almeida, Mdos S; De Aro, AA; De Oliveira, LP; Pimentel, ER; Vieira, CP, 2013) |
| "Pranlukast attenuates the progression of pulmonary fibrosis in the chronic phase but has no effect on the acute inflammatory response or on the onset of pulmonary fibrosis." | 1.38 | Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice. ( Okunishi, H; Shimbori, C; Shiota, N, 2012) |
| "Pulmonary silicosis is a deadly disease which kills thousands of people every year worldwide." | 1.36 | IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis. ( Chaudhury, BP; Chhabra, JK; Kumar, P; Mishra, V; Pandey, HP; Paul, B; Shukla, M; Tripathi, SS; Verma, M, 2010) |
| "Ovalbumin (OVA) was administered intraperitoneally to BALB/c mice on days 0 and 14, and the mice were then exposed to aerosolized OVA daily for 4 weeks." | 1.35 | Effects of KF19514, a phosphodiesterase 4 and 1 Inhibitor, on bronchial inflammation and remodeling in a murine model of chronic asthma. ( Fujimura, M; Kita, T; Myou, S; Nakao, S; Waseda, Y; Watanabe, K, 2009) |
| "This inflammation is accompanied by lower levels of CTGF and tissue inhibitor of metalloproteinase-1 gene expression compared with fibrosis-prone C57BL/6 mice." | 1.32 | Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs. ( Ask, K; Bonniaud, P; Gauldie, J; Kolb, M; Margetts, PJ; Martin, G; Robertson, J, 2004) |
| "In BALB/c mice, as in man, progressive pulmonary tuberculosis is accompanied by increasing expression of IL-4." | 1.32 | Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. ( Aguilar, D; Hernandez, ML; Hernandez-Pando, R; Orozco, H; Rook, G, 2004) |
| "Lung inflammation was measured by quantitative differential evaluation of lung lavage cells." | 1.32 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. ( Kenyon, NJ; Last, JA; Pinkerton, KE; Temple, L; Ward, R, 2004) |
| "In particular, idiopathic pulmonary fibrosis is a progressive and fatal form of the disorder characterized by alveolar inflammation, fibroblast proliferation and collagen deposition." | 1.31 | A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis. ( Ishii, S; Kita, Y; Nagase, T; Ohga, E; Ouchi, Y; Shimizu, T; Uozumi, N; Yamamoto, H, 2002) |
| "Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium, resulting in impaired lung function and respiratory failure." | 1.31 | Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. ( Bonniaud, P; Galt, T; Gauldie, J; Kelly, MM; Kolb, M; Margetts, PJ; Sime, PJ, 2002) |
| "We developed a mouse model for pulmonary fibrosis by intratracheal instillation of bleomycin (BLM)." | 1.31 | Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis. ( Fukuchi, Y; Ienaga, H; Kon, S; Maeda, K; Maeda, M; Okazaki, T; Takahashi, F; Takahashi, K; Uede, T, 2001) |
| "Lung hydroxyproline was also reduced in asbestos-exposed SCID mice after T lymphocyte reconstitution and, conversely, increased in T cell-depleted Balb/c mice." | 1.29 | A protective role for T lymphocytes in asbestos-induced pulmonary inflammation and collagen deposition. ( Blazka, ME; Corsini, E; Craig, WA; Luster, MI; Mahler, J; Rosenthal, GJ, 1994) |
| "Since pulmonary fibrosis develops even in nude athymic mice, T cells do not seem to play a primary part in fibrogenic response but they regulate, at least to some extent, the response of inflammatory cells and fibrogenesis of the lung." | 1.29 | T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice. ( Horiuchi, T; Ito, K; Kuwabara, M; Ohta, K; Shiga, J; Suzuki, N; Takizawa, H; Ueda, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (25.00) | 18.7374 |
| 1990's | 13 (9.03) | 18.2507 |
| 2000's | 26 (18.06) | 29.6817 |
| 2010's | 57 (39.58) | 24.3611 |
| 2020's | 12 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 3 |
| Li, M | 1 |
| Wang, R | 1 |
| Wang, B | 1 |
| Athari, SS | 1 |
| Wang, J | 2 |
| Yang, H | 1 |
| Wang, L | 1 |
| Yang, M | 1 |
| Hu, J | 1 |
| Zhang, E | 1 |
| Peng, L | 1 |
| Kumar, P | 2 |
| Yang, Z | 1 |
| Lever, JM | 1 |
| Chávez, MD | 1 |
| Fatima, H | 1 |
| Crossman, DK | 1 |
| Maynard, CL | 1 |
| George, JF | 1 |
| Mitchell, T | 1 |
| Johnstone, MA | 1 |
| Self, WT | 1 |
| Hernández-Bustabad, A | 1 |
| Morales-Arraez, D | 1 |
| González-Paredes, FJ | 1 |
| Abrante, B | 1 |
| Díaz-Flores, F | 1 |
| Abreu-González, P | 1 |
| de la Barreda, R | 1 |
| Quintero, E | 1 |
| Hernández-Guerra, M | 1 |
| Zhao, Z | 1 |
| Lv, D | 1 |
| Zhang, B | 2 |
| Yong, L | 1 |
| Zhang, R | 2 |
| Wang, X | 4 |
| Abdullah, A | 2 |
| Çiğdem, Y | 2 |
| Tuğrul, EE | 2 |
| Erhan, A | 2 |
| Horowitz, JC | 1 |
| Tschumperlin, DJ | 1 |
| Kim, KK | 1 |
| Osterholzer, JJ | 1 |
| Subbotina, N | 1 |
| Ajayi, IO | 1 |
| Teitz-Tennenbaum, S | 1 |
| Virk, A | 1 |
| Dotson, M | 1 |
| Liu, F | 1 |
| Sicard, D | 1 |
| Jia, S | 1 |
| Sisson, TH | 1 |
| Elfeky, MG | 1 |
| Mantawy, EM | 1 |
| Gad, AM | 1 |
| Fawzy, HM | 1 |
| El-Demerdash, E | 1 |
| A V, T | 1 |
| Mohanty, S | 1 |
| Dinda, AK | 1 |
| Koul, V | 1 |
| Qu, SJ | 1 |
| Zhao, L | 2 |
| Song, ZZ | 1 |
| Shen, WP | 1 |
| Ju, P | 1 |
| Li, YM | 1 |
| Guo, N | 1 |
| Yan, G | 1 |
| Wang, Q | 1 |
| Gao, T | 1 |
| Hou, N | 1 |
| Skurikhin, E | 1 |
| Madonov, P | 1 |
| Pershina, O | 1 |
| Ermakova, N | 1 |
| Pakhomova, A | 1 |
| Widera, D | 1 |
| Pan, E | 1 |
| Zhukova, M | 1 |
| Sandrikina, L | 1 |
| Artamonov, A | 1 |
| Dygai, A | 1 |
| Cook, CD | 1 |
| Hill, AS | 1 |
| Guo, M | 1 |
| Stockdale, L | 1 |
| Papps, JP | 1 |
| Isaacson, KB | 1 |
| Lauffenburger, DA | 1 |
| Griffith, LG | 1 |
| Li, F | 1 |
| Han, F | 1 |
| Li, H | 1 |
| Zhang, J | 1 |
| Qiao, X | 1 |
| Shi, J | 1 |
| Yang, L | 1 |
| Dong, J | 1 |
| Luo, M | 1 |
| Wei, J | 1 |
| Liu, X | 1 |
| Bashandy, SAE | 1 |
| Alaamer, A | 1 |
| Moussa, SAA | 1 |
| Omara, EA | 1 |
| Medina, JL | 1 |
| Sebastian, EA | 1 |
| Fourcaudot, AB | 1 |
| Dorati, R | 1 |
| Leung, KP | 1 |
| Raish, M | 1 |
| Ahmad, A | 1 |
| Ahmad Ansari, M | 1 |
| Ahad, A | 1 |
| Al-Jenoobi, FI | 1 |
| Al-Mohizea, AM | 1 |
| Khan, A | 1 |
| Ali, N | 1 |
| Hünerwadel, A | 1 |
| Fagagnini, S | 1 |
| Rogler, G | 1 |
| Lutz, C | 1 |
| Jaeger, SU | 1 |
| Mamie, C | 1 |
| Weder, B | 1 |
| Ruiz, PA | 1 |
| Hausmann, M | 1 |
| Mansour, HM | 1 |
| Salama, AAA | 1 |
| Abdel-Salam, RM | 1 |
| Ahmed, NA | 1 |
| Yassen, NN | 1 |
| Zaki, HF | 1 |
| Shariati, S | 1 |
| Kalantar, H | 1 |
| Pashmforoosh, M | 1 |
| Mansouri, E | 1 |
| Khodayar, MJ | 1 |
| Zhang, H | 1 |
| Yin, G | 1 |
| Jiang, H | 2 |
| Zhang, C | 2 |
| Vieira, CP | 2 |
| De Aro, AA | 2 |
| Da Ré Guerra, F | 1 |
| De Oliveira, LP | 1 |
| De Almeida, Mdos S | 2 |
| Pimentel, ER | 2 |
| Oryan, A | 1 |
| Moshiri, A | 1 |
| Meimandi-Parizi, A | 1 |
| Moura, LI | 1 |
| Dias, AM | 1 |
| Leal, EC | 1 |
| Carvalho, L | 1 |
| de Sousa, HC | 1 |
| Carvalho, E | 1 |
| Shutova, MI | 1 |
| Kozlov, SA | 1 |
| Zachvatov, AN | 1 |
| Kuznecov, SI | 1 |
| Anyushin, IL | 1 |
| Kong, X | 1 |
| Liu, C | 1 |
| Liang, Z | 1 |
| Zhao, H | 1 |
| Tong, W | 1 |
| Ning, G | 1 |
| Shen, W | 1 |
| Yao, L | 1 |
| Feng, S | 1 |
| Huang, X | 1 |
| Lv, Y | 1 |
| Xu, L | 1 |
| Lin, J | 1 |
| Diao, Y | 1 |
| Balaganur, V | 1 |
| Pathak, NN | 1 |
| Lingaraju, MC | 1 |
| More, AS | 1 |
| Latief, N | 1 |
| Kumari, RR | 1 |
| Kumar, D | 1 |
| Tandan, SK | 1 |
| Egger, C | 1 |
| Gérard, C | 1 |
| Vidotto, N | 1 |
| Accart, N | 1 |
| Cannet, C | 1 |
| Dunbar, A | 1 |
| Tigani, B | 1 |
| Piaia, A | 1 |
| Jarai, G | 1 |
| Jarman, E | 1 |
| Schmid, HA | 1 |
| Beckmann, N | 1 |
| Kurotsu, S | 1 |
| Tanaka, K | 1 |
| Niino, T | 1 |
| Asano, T | 1 |
| Sugizaki, T | 1 |
| Azuma, A | 2 |
| Suzuki, H | 1 |
| Mizushima, T | 1 |
| Shkurupiy, VA | 1 |
| Kim, LB | 1 |
| Potapova, OV | 1 |
| Cherdantseva, LA | 1 |
| Putyatina, AN | 1 |
| Nikonova, IK | 1 |
| Kwon, KD | 1 |
| Choi, MJ | 1 |
| Park, JM | 1 |
| Song, KM | 1 |
| Kwon, MH | 1 |
| Batbold, D | 1 |
| Yin, GN | 1 |
| Kim, WJ | 1 |
| Ryu, JK | 1 |
| Suh, JK | 1 |
| Chilakapati, SR | 1 |
| Serasanambati, M | 1 |
| Manikonda, PK | 1 |
| Chilakapati, DR | 1 |
| Watson, RR | 1 |
| Lv, P | 1 |
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3 reviews available for hydroxyproline and Innate Inflammatory Response
| Article | Year |
|---|---|
Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health.
Topics: Arginine; Creatinine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homoarginine; Humans; Hydro | 2016 |
Mediators of increased collagen synthesis in fibrosing organs.
Topics: Animals; Chemotactic Factors; Collagen; Connective Tissue; Cricetinae; Fibroblasts; Humans; Hydroxyp | 1985 |
[Effect of oxygen free radicals on collagen in inflammation].
Topics: Catalase; Collagen; Free Radicals; Hydroxyproline; Inflammation; Macrophages; NADP; Neutrophils; Oxy | 1986 |
141 other studies available for hydroxyproline and Innate Inflammatory Response
| Article | Year |
|---|---|
Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, | 2022 |
Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT.
Topics: Animals; Autophagy; Disease Models, Animal; Diterpenes, Kaurane; Hydroxyproline; Inflammation; Lipop | 2022 |
Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model.
Topics: Animals; Calcium Oxalate; Hydroxyproline; Inflammation; Kidney Calculi; Macrophages; Male; Nephrolit | 2022 |
d-Proline Reductase Underlies Proline-Dependent Growth of Clostridioides difficile.
Topics: Amino Acid Oxidoreductases; Amino Acids; Clostridioides; Clostridioides difficile; Glycine; Humans; | 2022 |
Chronic intermittent hypoxia promotes early intrahepatic endothelial impairment in rats with nonalcoholic fatty liver disease.
Topics: Acetaminophen; Acetylcholine; Animals; Hydroxyproline; Hypoxia; Inflammation; Intercellular Adhesion | 2022 |
Efficacy of Human-Recombinant Epidermal Growth Factor Combined with Povidone-Iodine for Pressure Ulcers and Its Influence on Inflammatory Cytokines.
Topics: Cytokines; Epidermal Growth Factor; Humans; Hydroxyproline; Immunologic Factors; Inflammation; Pain; | 2022 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Collagen; Doxycycline; Fibroblasts; Gene Expression Regulation; Genot | 2019 |
Mechanistic aspects of antifibrotic effects of honokiol in Con A-induced liver fibrosis in rats: Emphasis on TGF-β/SMAD/MAPK signaling pathways.
Topics: Actins; Animals; Biphenyl Compounds; Concanavalin A; Hydroxyproline; Inflammation; Lignans; Liver Ci | 2020 |
Fabrication and evaluation of gelatin/hyaluronic acid/chondroitin sulfate/asiatic acid based biopolymeric scaffold for the treatment of second-degree burn wounds - Wistar rat model study.
Topics: Animals; Biocompatible Materials; Bone Marrow Cells; Calorimetry, Differential Scanning; Cell Line; | 2020 |
Expression and significance of miR-223 in rats with pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Inflammation; Male; MicroRNAs; Pulmonary Fibrosis; | 2020 |
Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury by inhibiting inflammation via regulating the CD40/NF‑κB signaling pathway.
Topics: Acute Lung Injury; Animals; CD40 Antigens; Cells, Cultured; Cytokines; Ginkgolides; Hydroxyproline; | 2021 |
Micellar Hyaluronidase and Spiperone as a Potential Treatment for Pulmonary Fibrosis.
Topics: Animals; Cell Differentiation; Collagen Type I; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydroxypr | 2021 |
Local remodeling of synthetic extracellular matrix microenvironments by co-cultured endometrial epithelial and stromal cells enables long-term dynamic physiological function.
Topics: Cells, Cultured; Coculture Techniques; Collagen; Cytokines; DNA; Endometrium; Epithelial Cells; Extr | 2017 |
Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary fibrosis mice.
Topics: A549 Cells; Animals; Bleomycin; Cell Line; Female; Humans; Hydroxyproline; Inflammation; Interleukin | 2017 |
Role of zinc oxide nanoparticles in alleviating hepatic fibrosis and nephrotoxicity induced by thioacetamide in rats.
Topics: Actins; Animals; Biomarkers; Cytokines; Hydroxyproline; Inflammation; Kidney; Kidney Function Tests; | 2018 |
Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses.
Topics: Actins; Animals; Burns; Cicatrix; Cytokines; Hydroxyproline; Inflammation; Mice; Mice, Inbred C57BL; | 2019 |
Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Coumaric Acid | 2018 |
Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.
Topics: Animals; Colitis; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Hydroxyproline; | 2018 |
The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats.
Topics: Actins; Animals; Anti-Inflammatory Agents; Biomarkers; Collagen Type I; Cytokines; Gene Expression; | 2018 |
Epicatechin protective effects on bleomycin-induced pulmonary oxidative stress and fibrosis in mice.
Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Catalase; Catechin; Disease Models, Animal; Glutathion | 2019 |
High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; C-Reactiv | 2013 |
Inflammatory process induced by carrageenan in adjacent tissue triggers the acute inflammation in deep digital flexor tendon of rats.
Topics: Animals; Carrageenan; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Hydroxyproli | 2013 |
Implantation of a novel tissue-engineered graft in a large tendon defect initiated inflammation, accelerated fibroplasia and improved remodeling of the new Achilles tendon: a comprehensive detailed study with new insights.
Topics: Absorbable Implants; Achilles Tendon; Animals; Biomechanical Phenomena; Cattle; Cell Line; Coated Ma | 2014 |
Chitosan-based dressings loaded with neurotensin--an efficient strategy to improve early diabetic wound healing.
Topics: Animals; Bandages; Biocompatible Materials; Cell Line; Cell Survival; Chitosan; Collagen; Cytokines; | 2014 |
Experimental substantiation of the efficiency of antioxidant therapy for post-traumatic arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage; Cartilage, Articular; Collagen; Female; Hydroxyproline; | 2013 |
ERK2 small interfering RNAs prevent epidural fibrosis via the efficient inhibition of collagen expression and inflammation in laminectomy rats.
Topics: Animals; Collagen; Double-Blind Method; Epidural Space; Female; Fibrosis; Hydroxyproline; Inflammati | 2014 |
Protection effect of kallistatin on carbon tetrachloride-induced liver fibrosis in rats via antioxidative stress.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Cell Line; Collagen Type III; Hepatic Stell | 2014 |
Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Chondrocytes; Cytokines; Enzyme Inhibitors; | 2014 |
Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
Topics: Animals; Bleomycin; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Inflammation; Lung | 2014 |
Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.
Topics: Animals; Benzilates; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Death; Glutathione Tr | 2014 |
Fibrogenesis in granulomas and lung interstitium in tuberculous inflammation in mice.
Topics: Animals; BCG Vaccine; Cell Proliferation; Disease Models, Animal; Fibroblasts; Granuloma; Hydroxypro | 2014 |
Silencing histone deacetylase 2 using small hairpin RNA induces regression of fibrotic plaque in a rat model of Peyronie's disease.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Histone Deacetylase 2; Humans; Hydroxyp | 2014 |
Passion fruit peel extract attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Body Weight | 2014 |
An experimental novel study: hyperbaric oxygen treatment on reduction of epidural fibrosis via down-regulation of collagen deposition, IL-6, and TGF-β1.
Topics: Animals; Cicatrix; Collagen; Down-Regulation; Epidural Space; Fibroblasts; Fibrosis; Gene Expression | 2015 |
Effect of topically applied sildenafil citrate on wound healing: experimental study.
Topics: Acrylic Resins; Administration, Topical; Animals; Collagen; Dose-Response Relationship, Drug; Female | 2014 |
Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Elapid Venoms; Elapidae; Female; Fibrosi | 2014 |
Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats.
Topics: Amino Acids; Animals; Choline Deficiency; Food, Formulated; Glucosides; Hydroxyproline; Hypoglycemic | 2015 |
Proanthocyanidin from grape seed extract inhibits airway inflammation and remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Female; Grape Seed Extract | 2015 |
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice.
Topics: Animals; Chromatography, High Pressure Liquid; Collagen Type I; Collagen Type III; Diastole; Fibrosi | 2015 |
Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Collectins; Cytokines; Disease Models, A | 2015 |
Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress.
Topics: Animals; Cell Count; Diet, High-Fat; Endoplasmic Reticulum Stress; Fatty Liver; Female; Hydroxyproli | 2015 |
Symbiosis theory-directed green synthesis of silver nanoparticles and their application in infected wound healing.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Cytokines; Dynamic Light Scattering; Green | 2016 |
Attenuation effects of heparin-superoxide dismutase conjugate on bleomycin-induced lung fibrosis in vivo and radiation-induced inflammatory cytokine expression in vitro.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression; Heparin; | 2009 |
Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma.
Topics: Adaptation, Physiological; Adjuvants, Immunologic; Aminoquinolines; Animals; Asthma; Bronchoalveolar | 2009 |
Effects of KF19514, a phosphodiesterase 4 and 1 Inhibitor, on bronchial inflammation and remodeling in a murine model of chronic asthma.
Topics: Acetylcholine; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconst | 2009 |
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis.
Topics: Animals; Benzylisoquinolines; Bleomycin; Cell Line; Cell Proliferation; Cytokines; Endothelin-1; Gen | 2010 |
Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.
Topics: Anastomosis, Surgical; Animals; Colon; Everolimus; Hydroxyproline; Immunosuppressive Agents; Inflamm | 2011 |
Effect of diesel exhaust particles on house dust mite-induced airway eosinophilic inflammation and remodeling in mice.
Topics: Airway Remodeling; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Eosinophilia; G | 2010 |
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver | 2010 |
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Respo | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation | 2010 |
Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment.
Topics: Actins; Animals; Collagen; Cricetinae; Curcumin; Drug Administration Schedule; Gene Expression Regul | 2010 |
IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Colorimetry; Cytokines; Enzyme-Linked Immunosorbent Assay; Fe | 2010 |
A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis.
Topics: Animals; Bleomycin; Cytokines; Gene Expression Regulation; Hydroxyproline; Inflammation; Liposomes; | 2010 |
Hepatoprotection by freshwater clam extract against CCl4-induced hepatic damage in rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; | 2010 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, A | 2010 |
Inhibiting TGF-β activity improves respiratory function in mdx mice.
Topics: Animals; Biomarkers; Body Weight; Cell Adhesion Molecules; Creatine Kinase; Diaphragm; Dose-Response | 2011 |
Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Carbon Tetrachloride; Cy | 2011 |
Effects of acute inflammation induced in the rat paw on the deep digital flexor tendon.
Topics: Acute Disease; Animals; Carrageenan; Disease Models, Animal; Edema; Electrophoresis, Agar Gel; Extra | 2012 |
Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study.
Topics: Acetic Acid; Animals; Anti-Infective Agents; Capillary Permeability; Disease Models, Animal; Hydroxy | 2012 |
Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Animal; Enzy | 2012 |
Antifibrotic effects of Artemisia capillaris and Artemisia iwayomogi in a carbon tetrachloride-induced chronic hepatic fibrosis animal model.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Artemisia; Carbon Tetrachloride; Chemical and Drug Indu | 2012 |
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cell Proliferation; Disease Models, Animal; Female; | 2012 |
In vivo and in vitro lung mechanics by forced oscillations: effect of bleomycin challenge.
Topics: Airway Resistance; Animals; Antibiotics, Antineoplastic; Bleomycin; Elasticity; Extravascular Lung W | 2012 |
Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chromones; Cytokines; Disease Progression; Female; Hydroxypro | 2012 |
The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine.
Topics: Animals; Antioxidants; Bleomycin; Grape Seed Extract; Hydroxyproline; Inflammation; Lung; Lymphocyte | 2012 |
Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Bronchoalveolar Lavage; Cytokines; Drinking Wat | 2012 |
The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster.
Topics: Airway Remodeling; Animals; Biomarkers; Collagen; Cricetinae; Cystathionine beta-Synthase; Extracell | 2012 |
Paracetamol does not compromise early wound repair in the intestine or abdominal wall in the rat.
Topics: Abdominal Injuries; Acetaminophen; Analgesics, Non-Narcotic; Anastomosis, Surgical; Animals; Biomech | 2012 |
Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats.
Topics: Amines; Angiogenesis Inducing Agents; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bact | 2012 |
Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains.
Topics: Adenoviridae; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Collagen; Female; Fibroblasts; Gene | 2002 |
Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Mode | 2002 |
Susceptibility to ovalbumin-induced airway inflammation and fibrosis in inducible nitric oxide synthetase-deficient mice: mechanisms and consequences.
Topics: Aerosols; Animals; Cell Count; Collagen; Coloring Agents; Fibrosis; Gene Expression Regulation, Enzy | 2003 |
Candesartan, an angiotensin II receptor antagonist, suppresses pancreatic inflammation and fibrosis in rats.
Topics: Actins; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl | 2003 |
Soluble collagen in acute inflammation.
Topics: Collagen; Hydroxyproline; Inflammation; Palate | 1962 |
CHEMISTRY OF INFLAMMATION.
Topics: Adrenalectomy; Atropine; Collagen; Croton Oil; Hexosamines; Histocytochemistry; Hydroxyproline; Infl | 1963 |
[EFFECT OF ACUTE INFLAMMATION ON THE DISTRIBUTION AND ELIMINATION OF QUARTZ DUST FROM RABBIT LUNGS. EXPERIMENTAL STUDY ON ELIMINATION OF DUST FROM THE LUNGS. III].
Topics: Animals; Bronchitis; Dust; Hexosamines; Hydroxyproline; Inflammation; Lung; Lung Diseases; Pneumocon | 1963 |
DERMATOLOGIC ASPECTS OF MAST CELL ACTIVITY.
Topics: Chondroitin; Coloring Agents; Cushing Syndrome; Dermatology; Erythema Multiforme; Heparin; Hexosamin | 1964 |
[COMPARATIVE STUDIES ON THE COLLAGEN BREAKDOWN IN INFLAMED AND LATHYRITICALLY CHANGED TISSUES].
Topics: Aminopropionitrile; Collagen; Cyanides; Hydroxyproline; Inflammation; Lathyrism; Rats; Research; Ten | 1963 |
THE EFFECT OF "STRESS" AND CORTISOL UPON THE CHEMISTRY OF INFLAMMATION.
Topics: Croton Oil; Fucose; Glycoproteins; Hexosamines; Hexoses; Hydrocortisone; Hydroxyproline; Inflammatio | 1964 |
THE EFFECT OF AGE ON THE CHEMISTRY OF INFLAMMATION.
Topics: Aging; Collagen; Croton Oil; Edema; Fucose; Glycoproteins; Hexosamines; Hexoses; Hydroxyproline; Inf | 1964 |
THE CHEMICAL COMPOSITION OF THE OEDEMA FLUID DURING THE COURSE OF ACUTE INFLAMMATION.
Topics: Animals; Blood; Body Fluids; Chemistry Techniques, Analytical; Chlorides; Edema; Hexosamines; Hydrox | 1964 |
QUANTITATIVE INVESTIGATIONS ON THE COMPOSITION OF ACUTE INFLAMMATORY EDEMA.
Topics: Animals; Chlorides; Edema; Hexosamines; Hot Temperature; Hydroxyproline; Inflammation; Metabolism; M | 1964 |
EFFECTS OF ANTI-INFLAMMATORY AGENTS ON THE CHEMICAL COMPOSITON OF NORMAL AND INFLAMED CONNECTIVE TISSUE.
Topics: Animals; Anti-Inflammatory Agents; Chlorides; Connective Tissue; Edema; Exudates and Transudates; He | 1964 |
Effect of richlocaine alone or in combination with energostim on the severity of endotoxemia and survival of the skin under conditions of reduced blood flow.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cell Survival; Cytochromes | 2003 |
Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ozone.
Topics: Aerosols; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Coloring Agents; Fibrosis; Hydroxyproli | 2004 |
Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.
Topics: Animals; Granuloma; Hydroxyproline; Hypersensitivity, Delayed; Inflammation; Interferon-gamma; Inter | 2004 |
Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles.
Topics: Air Pollutants; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Dr | 2004 |
Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs.
Topics: Adenoviridae; Animals; Bleomycin; Bronchoalveolar Lavage; Connective Tissue Growth Factor; DNA Prime | 2004 |
Involvement of the NF-kappa B/matrix metalloproteinase pathway in cardiac fibrosis of mice lacking guanylyl cyclase/natriuretic peptide receptor A.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Blotting, Western; Cell Nucleu | 2005 |
Role of free radicals in aseptic loosening of hip arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Female; Fibrosis; Free Radicals; Glu | 2006 |
Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase.
Topics: Animals; Asbestos, Crocidolite; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lu | 2006 |
Mycophenolate mofetil impairs the integrity of colonic anastomosis.
Topics: Anastomosis, Surgical; Animals; Colon; Fibroblasts; Hydroxyproline; Immunohistochemistry; Immunosupp | 2006 |
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Gene Expression Regulation; Hydroxyproline; Inflammation; Liver Cirrh | 2006 |
Pifithrin-alpha, an inhibitor of p53 transactivation, alters the inflammatory process and delays tendon healing following acute injury.
Topics: Achilles Tendon; Animals; Apoptosis; Benzothiazoles; Biomechanical Phenomena; Caspase 3; Collagen; C | 2007 |
Inflammatory cells do not decrease the ultimate tensile strength of intact tendons in vivo and in vitro: protective role of mechanical loading.
Topics: Animals; Biomechanical Phenomena; Carrageenan; Collagen; Female; Hydroxyproline; Inflammation; Leuko | 2007 |
Inflammatory related changes in lung tissue mechanics after bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Elasticity; Extravascular Lung Water; Hydroxyprolin | 2008 |
The effect of 6-mercaptopurine on the inflammatory response stimulated by subcutaneous implantation of polyvinyl sponge.
Topics: Animals; Connective Tissue; Foreign Bodies; Granuloma; Granuloma, Giant Cell; Guinea Pigs; Hydroxypr | 1967 |
A genetically engineered mutant of alpha 1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease.
Topics: alpha 1-Antitrypsin; Basement Membrane; Connective Tissue; Genetic Engineering; Humans; Hydroxyproli | 1984 |
Quantification of the inflammatory reaction and collagen accumulation in an experimental model of open wounds in the rat. A methodological study.
Topics: Animals; Blood Flow Velocity; Body Water; Collagen; Exudates and Transudates; Granulation Tissue; Hy | 1982 |
The artificial granuloma. III. Collagen synthesis during the cell-mediated granulomatous response as determined in explanted granulomas.
Topics: Animals; Antigens; Collagen; Female; Granuloma; Hydroxyproline; Immunity, Cellular; Inflammation; Lu | 1981 |
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL4; Cytokines; Enzyme-Linked Immunosor | 1994 |
Antigen-induced alveolitis: cytokine production in a mouse model.
Topics: Alveolitis, Extrinsic Allergic; Animals; Antigens; Bronchoalveolar Lavage Fluid; Cytokines; Erythroc | 1995 |
A protective role for T lymphocytes in asbestos-induced pulmonary inflammation and collagen deposition.
Topics: Animals; Asbestos, Serpentine; Asbestosis; Base Sequence; Bronchoalveolar Lavage Fluid; Collagen; Di | 1994 |
Mineral dusts cause elastin and collagen breakdown in the rat lung: a potential mechanism of dust-induced emphysema.
Topics: Animals; Bronchoalveolar Lavage Fluid; Collagen; Desmosine; Dust; Elastin; Hydroxyproline; Inflammat | 1996 |
Topically applied halofuginone, an inhibitor of collagen type I transcription, reduces peritendinous fibrous adhesions following surgery.
Topics: Animals; Chickens; Collagen; Gene Expression Regulation; Hydroxyproline; Inflammation; Piperidines; | 1996 |
T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lung Diseases; Male; Mice | 1996 |
Silica exposure increases expression of pulmonary intercellular adhesion molecule-1 (ICAM-1) in C57Bl/6 mice.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Collagen; Dose- | 1996 |
Role of interleukin-10 in the lung response to silica in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Female; Hydroxyproline; In | 1998 |
Diphenylhydantoin sodium promotes early and marked angiogenesis and results in increased collagen deposition and tensile strength in healing wounds.
Topics: Animals; Collagen; Hydroxyproline; Inflammation; Male; Neovascularization, Physiologic; Phenytoin; P | 1998 |
Relationship of keratinocyte growth factor and hepatocyte growth factor levels in rat lung lavage fluid to epithelial cell regeneration after bleomycin.
Topics: Animals; Autoradiography; Bleomycin; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay | 1999 |
Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Disease Models, Animal; Hydr | 2001 |
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions.
Topics: Animals; Apoptosis; Eosinophils; Fibrosis; Gene Expression Profiling; Genotype; Hydroxyproline; Infl | 2001 |
The role of L-arginine and neutrophils on incisional wound healing.
Topics: Animals; Arginine; Collagen; Fibroblasts; Hydroxyproline; Inflammation; Neutrophils; Rats; Rats, Wis | 2001 |
A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cytosol; Eicosanoids; Hydroxyproline; In | 2002 |
The effects of corticosteroids on the healing of tracheal anastomoses in a rat model.
Topics: Adrenal Cortex Hormones; Anastomosis, Surgical; Animals; Collagen; Coloring Agents; Dose-Response Re | 2002 |
Doxycycline and tissue repair in rats.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cicatrix; Collagen; Collagen Type I; Coloring | 2002 |
Hydroxyproline-containing structural glycopeptide fractions from subacute inflammation connective tissue.
Topics: Amino Acids; Animals; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Collagen; | 1976 |
[Urinary hydroxylysine excretion as an index of systemic collagen disorders].
Topics: Bone Diseases; Collagen; Collagen Diseases; Female; Humans; Hydroxylysine; Hydroxyproline; Inflammat | 1977 |
Clinical and biochemical assessment of anti-inflammatory substances.
Topics: Acute Disease; Anti-Inflammatory Agents; Drug Evaluation; Humans; Hydroxyproline; Immunoglobulin A; | 1976 |
Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop
Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Collagen; Dimethylnitrosamine; Female; Fibrosis | 1992 |
The effect of prostaglandin E1 on colonic anastomotic healing. A comparison study.
Topics: Alprostadil; Anastomosis, Surgical; Animals; Aprotinin; Collagen; Colon; Hydroxyproline; Inflammatio | 1990 |
Mediators, initiating the inflammatory response, released in organ culture by full-thickness human skin explants exposed to the irritant, sulfur mustard.
Topics: Administration, Cutaneous; Dinoprostone; Histamine Release; Humans; Hydrolases; Hydroxyproline; Infl | 1991 |
[Mechanism of action of pronase on chronic proliferative inflammation including granuloma angiogenesis in mice].
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Granuloma; Hydrocortisone; Hydroxyproline; Indom | 1986 |
The course of healing of the inflammatory granuloma in rats after the application of tetrachlormethane and 6-azauridine.
Topics: Animals; Azauridine; Carbon Tetrachloride; Glycoproteins; Granuloma; Hydroxyproline; Inflammation; L | 1985 |
Biphasic cellular and tissue response of rat lungs after eight-day aerosol exposure to the silicon dioxide cristobalite.
Topics: Aerosols; Animals; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lymphocytes; Ma | 1989 |
[Sclerodermiform porphyria cutanea tarda. Ultrastructural study].
Topics: Aged; Animals; Bicarbonates; Cricetinae; Diabetes Complications; Diagnosis, Differential; Hemorrhage | 1985 |
Influence of prednisolone and methotrexate on cellular and biochemical aspects of acute and chronic inflammation studied in subcutaneously implanted sponges in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Chronic Disease; Collagen; Glycosaminoglycans; Hyd | 1986 |
Urine and tissue glycosaminoglycans and their interrelations.
Topics: Adolescent; Animals; Chemical Fractionation; Chemical Phenomena; Chemistry; Child; Child, Preschool; | 1986 |
Effects of zinc oxide in an occlusive, adhesive dressing on granulation tissue formation.
Topics: Acid Phosphatase; Administration, Topical; Alkaline Phosphatase; Animals; Bandages; Collagen; Female | 1986 |
The effects of the glucocorticoids on connective tissue.
Topics: Biochemical Phenomena; Biochemistry; Biopsy; Connective Tissue; Depression, Chemical; Glucocorticoid | 1969 |
[Influence of various drugs on the tissue permeability. 6. Effect of anti-inflammatory drugs on quantitative changes in connective tissue components in inflamed tissues of filter paper-implanted rats].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Barbiturates; Benzyl Compounds; Connective | 1973 |
[Changes in local and systemic parameters in the rat exposed to an inflammatory process. I].
Topics: Animals; Blood Proteins; Blood Viscosity; Carrageenan; Female; Fibrinogen; Glucose-6-Phosphatase; Gl | 1971 |
[Biochemical studies on action mechnism of a new anti-inflammatory agent, naproxen (1). Effects of naproxen on changes in connective tissue components due to inflammation].
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Connective Tissue; Dimethylamines; Female; Gran | 1974 |
[On the variations of activity of several cathepsins observed in the inflammatory centers of experimental origin].
Topics: Animals; Anti-Inflammatory Agents; Cathepsins; Hydroxyproline; Inflammation; Rats; Tyrosine | 1968 |
Inhibitory effects of vitamin E on collagen synthesis and wound repair.
Topics: Animals; Body Weight; Collagen; Hydroxyproline; Inflammation; Male; Polyvinyls; Prednisolone; Rats; | 1972 |
Biochemical investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 2. Action on local and systemic chemical responses in the rat with an experimental inflammatory process.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Proteins; Carrageenan; Collagen; Female; Fibrinoge | 1972 |
Study on the idiopathic cardiomyopathy. Diagnostic value of the apexcardiogram, 131 Cs scintiscanning of the heart and plasma hydroxyproline.
Topics: Adult; Amyl Nitrite; Autopsy; Cardiomyopathies; Cesium Isotopes; Child; Collagen; Collagen Diseases; | 1971 |
[Effects of thyroxine and carnitines on the experimental inflammations].
Topics: Animals; Carnitine; Collagen; Edema; Exudates and Transudates; Foreign Bodies; Granulation Tissue; H | 1967 |
A quantitative method for studying formation, composition and dynamics of inflammatory oedema fluid.
Topics: Animals; Blood; Chemical Phenomena; Chemistry; Chlorides; Edema; Exudates and Transudates; Hexosamin | 1965 |