Page last updated: 2024-11-06

hydroxyproline and Injury, Ischemia-Reperfusion

hydroxyproline has been researched along with Injury, Ischemia-Reperfusion in 14 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Oxaceprol, an established drug for treatment of degenerative joint disease, has recently been shown in vitro to reduce leukocyte adhesion to cultured endothelial cells and leukocyte extravasation in vivo in an arthritis animal model."7.70Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury. ( Harris, A; Messmer, K; Schropp, A, 1998)
"Genistein is a natural isoflavonoid and has several pharmacological effects, such as antioxidant, antitumor activity, and improvement of glucose metabolism."5.72The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury. ( Akıncı, O; Kepil, N; Tosun, Y, 2022)
"Pyrrolidine dithiocarbamate (PDTC) is a low-molecular-weight thiol antioxidant and potent inhibitor of nuclear factor-kappaB (NF-kappaB) activation."5.34Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats. ( Aydin, C; Aytekin, FO; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Tekin, K; Yenisey, C, 2007)
"The aim of this study was to examine whether treatment with montelukast, a selective leukotriene antagonist, would affect anastomotic healing in a reperfused colon rat model with remote ischemia/reperfusion injury."3.79Effects of montelukast on the healing of ischemic colon anastomoses. ( Altinli, E; Celik, A; Celik, AS; Ergun, E; Eroglu, E; Kemik, A; Koksal, N; Uzun, MA, 2013)
"Oxaceprol, an established drug for treatment of degenerative joint disease, has recently been shown in vitro to reduce leukocyte adhesion to cultured endothelial cells and leukocyte extravasation in vivo in an arthritis animal model."3.70Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury. ( Harris, A; Messmer, K; Schropp, A, 1998)
"Genistein is a natural isoflavonoid and has several pharmacological effects, such as antioxidant, antitumor activity, and improvement of glucose metabolism."1.72The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury. ( Akıncı, O; Kepil, N; Tosun, Y, 2022)
"Pyrrolidine dithiocarbamate (PDTC) is a low-molecular-weight thiol antioxidant and potent inhibitor of nuclear factor-kappaB (NF-kappaB) activation."1.34Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats. ( Aydin, C; Aytekin, FO; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Tekin, K; Yenisey, C, 2007)
"Hydroxyproline and histology were not different between groups."1.34A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat. ( Bleichrodt, RP; Hendriks, T; Posma, LA; van Goor, H, 2007)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's7 (50.00)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Akıncı, O1
Tosun, Y1
Kepil, N1
Celik, A2
Ergun, E1
Koksal, N1
Celik, AS1
Altinli, E1
Uzun, MA1
Eroglu, E1
Kemik, A1
Assis de Brito, TL1
Monte-Alto-Costa, A1
Romana-Souza, B1
Marjanovic, G1
Jüttner, E1
zur Hausen, A1
Theodor Hopt, U1
Obermaier, R1
Teke, Z2
Bostanci, EB1
Yenisey, C2
Kelten, EC1
Sacar, M2
Simsek, NG1
Duzcan, SE1
Akoglu, M1
Tireli, GA1
Salman, T1
Ozbey, H1
Abbasoglu, L1
Toker, G1
Harris, AG1
Schropp, A2
Messmer, K2
Posma, LA2
Bleichrodt, RP2
van Goor, H2
Hendriks, T2
Aytekin, FO1
Kabay, B1
Aydin, C1
Tekin, K1
Ozden, A1
Demiroğullari, B1
Sönmez, K1
Türkyilmaz, Z1
Ekingen, G1
Dursun, A1
Bor, V1
Türközkan, N1
Başaklar, AC1
Kale, N1
Harris, A1
Kologlu, M1
Yorganci, K1
Renda, N1
Sayek, I1
Appenroth, D1
Lupp, A1
Kriegsmann, J1
Sawall, S1
Splinther, J1
Sommer, M1
Stein, G1
Fleck, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Preoperative Embolization of the Inferior Mesenteric Artery in Colorectal Surgery[NCT05422560]30 participants (Anticipated)Interventional2022-09-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

14 other studies available for hydroxyproline and Injury, Ischemia-Reperfusion

ArticleYear
The Effect of Genistein on Anastomotic Healing in Intestinal Ischemia/Reperfusion Injury.
    The Journal of surgical research, 2022, Volume: 280

    Topics: Anastomosis, Surgical; Animals; Antioxidants; Colon; Genistein; Glucose; Glutathione Peroxidase; Hyd

2022
Effects of montelukast on the healing of ischemic colon anastomoses.
    American journal of surgery, 2013, Volume: 206, Issue:4

    Topics: Acetates; Alanine Transaminase; Anastomosis, Surgical; Animals; Aspartate Aminotransferases; Caspase

2013
Propranolol impairs the closure of pressure ulcers in mice.
    Life sciences, 2014, Apr-01, Volume: 100, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blotting, Western; Epidermis; Hydroxyproline; Immunoenzyme Tec

2014
Ischemic preconditioning improves stability of intestinal anastomoses in rats.
    International journal of colorectal disease, 2009, Volume: 24, Issue:8

    Topics: Anastomosis, Surgical; Animals; Constriction; Digestive System Surgical Procedures; Hydroxyproline;

2009
Caffeic acid phenethyl ester prevents detrimental effects of remote ischemia-reperfusion injury on healing of colonic anastomoses.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2013, Volume: 26, Issue:1

    Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Colon; Cytok

2013
The effect of pentoxifylline on intestinal anastomotic healing after ischemia.
    Pediatric surgery international, 2003, Volume: 19, Issue:1-2

    Topics: Anastomosis, Surgical; Animals; Hematologic Agents; Hydroxyproline; Intestine, Small; Male; Mesenter

2003
[Oxaceprol reduced leukocyte adhesion and extravasation and preserves perfusion of tissue after ischemia/reperfusion].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115, Issue:Suppl I

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Adhesion; Cricetinae;

1998
Transient profound mesenteric ischemia strongly affects the strength of intestinal anastomoses in the rat.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:7

    Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Follow-Up Studies; Gelatinases; Hydro

2007
Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats.
    World journal of surgery, 2007, Volume: 31, Issue:9

    Topics: Anastomosis, Surgical; Animals; Antioxidants; Colon; Colonic Diseases; Disease Models, Animal; Gluta

2007
A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat.
    International journal of colorectal disease, 2007, Volume: 22, Issue:12

    Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Ileum; Ischemia; Male

2007
Comparison of consequent small bowel anastomoses after transient ischemia: an experimental study in rats.
    Journal of pediatric surgery, 1998, Volume: 33, Issue:1

    Topics: Anastomosis, Surgical; Animals; Hydroxyproline; Intestine, Small; Male; Mesenteric Artery, Superior;

1998
Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury.
    European journal of medical research, 1998, Apr-08, Volume: 3, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cell Adhesion; Cricetinae; Dextrans; Di

1998
Effect of local and remote ischemia-reperfusion injury on healing of colonic anastomoses.
    Surgery, 2000, Volume: 128, Issue:1

    Topics: Anastomosis, Surgical; Animals; Colon; Female; Hindlimb; Hydroxyproline; Intestine, Small; Kidney; P

2000
Temporary warm ischaemia, 5/6 nephrectomy and single uranyl nitrate administration--comparison of three models intended to cause renal fibrosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:4

    Topics: Animals; Creatinine; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Kidney; Nephrectomy;

2001