Compounds > hydroxyproline
Page last updated: 2024-11-06

hydroxyproline and Inappropriate GH Secretion Syndrome (Acromegaly)

hydroxyproline has been researched along with Inappropriate GH Secretion Syndrome (Acromegaly) in 48 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Eight selected patients with active acromegaly and elevated GH levels without other endocrine disturbances were submitted to long-term treatment and acute dose-response trials with bromocriptine."9.04Bromocriptine treatment in acromegaly: clinical and biochemical effects. ( Bohmer, T; Halse, J; Haugen, HN, 1977)
"Eleven patients with active acromegaly were treated with bromocriptine for one year or more."9.04Bromocriptine therapy in eleven patients with acromegaly. ( Boström, H; Ljunghall, S; Lundin, L; Wide, L, 1978)
"A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0."7.66Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978)
"Urinary excretion of hydroxyproline was examined with the Hypronosticon test in 25 patients with acromegaly (13 men, 12 women) and 15 healthy persons."7.65[Urinary excretion of hydroxyproline in acromegaly (author's transl)]. ( Irmscher, K; Krüskemper, HL; Lepszy, H; Solbach, HG; Wiegelmann, W, 1976)
"Eight selected patients with active acromegaly and elevated GH levels without other endocrine disturbances were submitted to long-term treatment and acute dose-response trials with bromocriptine."5.04Bromocriptine treatment in acromegaly: clinical and biochemical effects. ( Bohmer, T; Halse, J; Haugen, HN, 1977)
"Eleven patients with active acromegaly were treated with bromocriptine for one year or more."5.04Bromocriptine therapy in eleven patients with acromegaly. ( Boström, H; Ljunghall, S; Lundin, L; Wide, L, 1978)
" In eight patients with active acromegaly, urinary free pyridinoline and deoxypyridinoline, and serum osteocalcin, propeptide of type 1 procollagen, vitamin D, 1000 h parathyroid hormone, bone specific alkaline phosphatase, calcium and phosphate concentrations were measured before and after 6 months treatment with octreotide."3.70Gonadal status is an important determinant of bone density in acromegaly. ( Farquharson, R; Fraser, WD; Hipkin, L; Lesse, GP; Vora, JP, 1998)
"A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0."3.66Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978)
"Urinary excretion of hydroxyproline was examined with the Hypronosticon test in 25 patients with acromegaly (13 men, 12 women) and 15 healthy persons."3.65[Urinary excretion of hydroxyproline in acromegaly (author's transl)]. ( Irmscher, K; Krüskemper, HL; Lepszy, H; Solbach, HG; Wiegelmann, W, 1976)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199043 (89.58)18.7374
1990's3 (6.25)18.2507
2000's2 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BENOIT, FL2
THEIL, GB1
WATTEN, RH2
JOHNSTON, CC1
DEISS, WP1
Cappelli, C1
Gandossi, E1
Agosti, B1
Cerudelli, B1
Cumetti, D1
Castellano, M1
Pirola, I1
De Martino, E1
Rosei, EA1
Biermasz, NR1
Hamdy, NA1
Pereira, AM1
Romijn, JA1
Roelfsema, F1
Borel, JP1
Caranjot, JM1
Jayle, MF1
Bijlsma, JW1
Nortier, JW1
Duursma, SA1
Croughs, RJ1
Bosch, R1
Thijssen, JH1
Marek, J4
Srámková, J1
Schüllerová, M1
Stĕpán, J4
Schreiberová, O1
Halse, J4
Gordeladze, JO3
Clemmons, DR1
Underwood, LE1
Ridgway, EC1
Kliman, B1
Kjellberg, RN1
Van Wyk, JJ1
Marazuela, M1
Astigarraga, B1
Tabuenca, MJ1
Estrada, J1
Marín, F1
Lucas, T1
Kotzmann, H1
Bernecker, P1
Hübsch, P1
Pietschmann, P1
Woloszczuk, W1
Svoboda, T1
Geyer, G1
Luger, A1
Lesse, GP1
Fraser, WD1
Farquharson, R1
Hipkin, L1
Vora, JP1
Havránek, T2
Dolezal, V2
Pacovský, V2
Horn, V1
Silinková-Málková, E1
Vokrouhlická, O1
Konopásek, B1
Formánková, J2
Hrba, J1
Haugen, HN2
Bohmer, T2
Lundin, L1
Ljunghall, S1
Wide, L1
Boström, H1
Belforte, L1
Camanni, F1
Chiodini, PG1
Liuzzi, A1
Massara, F1
Molinatti, GM1
Müller, EE1
Silvestrini, F1
Rodnan, GP1
Lipinski, E1
Luksick, J1
Djøoseland, O1
Leicht, E1
Langer, HJ1
Stelzer, K1
Blum, C1
Thorner, MO2
Besser, GM2
Chait, A1
Aitken, M1
Benker, G1
Bloom, SR1
Mortimer, CH1
Sanders, P1
Mason, AS1
Touliatos, J1
Lindholm, BW1
Lepszy, H1
Irmscher, K1
Wiegelmann, W1
Solbach, HG1
Krüskemper, HL1
Oberländer, J1
Bottermann, P1
Kozak, GP1
Vagnucci, AI1
Lauler, DP1
Thorn, GW1
Rake, JS1
Hafiz, SA1
Lessof, MH1
Snodgrass, GJ1
Dinulescu, E1
Ganea, E2
Olteanu, M1
Vontobel, F1
Nikkilä, EA1
Pelkonen, R1
Taskinen, MR1
Aro, A1
Ege, P1
Laron, Z1
Pertzelan, A1
Karp, M1
Kowadlo-Silbergeld, A1
Daughaday, WH2
Haddad, JG1
Couranz, S1
Avioli, LV1
Wiedemann, E1
Schwartz, E2
Kocher, P1
Kivirikko, KI1
Cerda, JJ1
Toskes, PP1
Shopa, NA1
Wilkinson, JH1
Recchia, O1
Sereno, L1
Isidori, A1
Katz, FH1
Kappas, A1
Zatońska, I1
Widomska-Czekajska, T1
Echemendia, E1
Schiffer, M1
Panariello, VA1
Bell, NH1
Colwell, JA1
Saval, F1
Del Greco, F1
Casey, DE1

Reviews

3 reviews available for hydroxyproline and Inappropriate GH Secretion Syndrome (Acromegaly)

ArticleYear
[Urine hydroxyproline a review].
    Ugeskrift for laeger, 1968, Oct-17, Volume: 130, Issue:42

    Topics: Acromegaly; Bone Resorption; Carbon Isotopes; Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hyp

1968
The biosynthesis of collagen.
    Acta rheumatologica Scandinavica, 1971, Volume: 17, Issue:3

    Topics: Acromegaly; Ascorbic Acid Deficiency; Carbon Isotopes; Collagen; Ehlers-Danlos Syndrome; Hydroxylati

1971
Regulation of skeletal growth by sulfation factor.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Acromegaly; Bone and Bones; Bone Development; Cartilage; Chondroitin; DNA; Dwarfism, Pituitary; Grow

1971

Trials

3 trials available for hydroxyproline and Inappropriate GH Secretion Syndrome (Acromegaly)

ArticleYear
Bromocriptine treatment in acromegaly: clinical and biochemical effects.
    Acta endocrinologica, 1977, Volume: 86, Issue:3

    Topics: Acromegaly; Adult; Bromocriptine; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response R

1977
Bromocriptine therapy in eleven patients with acromegaly.
    Acta endocrinologica. Supplementum, 1978, Volume: 216

    Topics: Acromegaly; Adult; Aged; Bromocriptine; Clinical Trials as Topic; Drug Evaluation; Female; Glucose T

1978
Administration of growth hormone to patients with familial dwarfism with high plasma immunoreactive growth hormone: measurement of sulfation factor, metabolic and linear growth responses.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Blood; Blood Glucose; Body Weight; Calcium; Child; Child, Preschool;

1971

Other Studies

42 other studies available for hydroxyproline and Inappropriate GH Secretion Syndrome (Acromegaly)

ArticleYear
HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Anabolic Agents; Cushing Syndrome;

1963
PARATHYROID HORMONE AND URINARY HYDROXYPROLINE.
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Acromegaly; Adenoma; Adolescent; Blood; Calcium; Calcium, Dietary; Geriatrics; Humans; Hydroxyprolin

1965
Long-term treatment of acromegaly with lanreotide: evidence of increased serum parathormone concentration.
    Endocrine journal, 2004, Volume: 51, Issue:6

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Calcifediol; Calcitriol; Calcium; Female; Humans; Hyd

2004
Long-term maintenance of the anabolic effects of GH on the skeleton in successfully treated patients with acromegaly.
    European journal of endocrinology, 2005, Volume: 152, Issue:1

    Topics: Absorptiometry, Photon; Acromegaly; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and B

2005
[A method of fractionating urinary peptides containing hydroxyproline].
    Clinica chimica acta; international journal of clinical chemistry, 1967, Volume: 16, Issue:3

    Topics: Acromegaly; Arthritis, Rheumatoid; Bone Neoplasms; Chemistry, Clinical; Chromatography, Ion Exchange

1967
Changes in bone metabolism during treatment of acromegaly.
    Acta endocrinologica, 1983, Volume: 104, Issue:2

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Acid Phosphatase; Acromegaly; Adult; Aged; Bone and Bones;

1983
Long-term treatment of acromegaly with lisuride: differences of effect on growth hormone and somatomedin.
    Endokrinologie, 1981, Volume: 78, Issue:2-3

    Topics: Acromegaly; Adult; Alkaline Phosphatase; Blood Glucose; Bone and Bones; Bromocriptine; Ergolines; Fe

1981
Total and non-dialyzable urinary hydroxyproline in acromegalics and control subjects.
    Acta endocrinologica, 1981, Volume: 96, Issue:4

    Topics: Acromegaly; Age Factors; Aged; Bone and Bones; Calcium; Collagen; Female; Growth Hormone; Humans; Hy

1981
Estradiol treatment of acromegaly. Reduction of immunoreactive somatomedin-C and improvement in metabolic status.
    The American journal of medicine, 1980, Volume: 69, Issue:4

    Topics: Acromegaly; Adult; Aged; Estradiol; Female; Growth Hormone; Humans; Hydroxyproline; Male; Middle Age

1980
Serum bone Gla protein as a marker of bone turnover in acromegaly.
    Calcified tissue international, 1993, Volume: 52, Issue:6

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Female; Humans; Hydroxypr

1993
Bone mineral density and parameters of bone metabolism in patients with acromegaly.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:4

    Topics: Absorptiometry, Photon; Acromegaly; Adult; Aged; Bone Density; Female; Femur Neck; Growth Hormone; H

1993
Gonadal status is an important determinant of bone density in acromegaly.
    Clinical endocrinology, 1998, Volume: 48, Issue:1

    Topics: Acromegaly; Amino Acids; Biomarkers; Bone Density; Bone Remodeling; Case-Control Studies; Female; Fe

1998
Bone isoenzyme of serum alkaline phosphatase in acromegaly.
    Clinica chimica acta; international journal of clinical chemistry, 1979, May-02, Volume: 93, Issue:3

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Calcium; Female; gamma-Glutamyltransf

1979
Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases.
    European journal of clinical investigation, 1978, Volume: 8, Issue:6

    Topics: Acromegaly; Adult; Alkaline Phosphatase; Bone Diseases; Bone Neoplasms; Female; Humans; Hydroxyproli

1978
Long-term treatment with 2-Br-alpha-ergocryptine in acromegaly.
    Acta endocrinologica, 1977, Volume: 85, Issue:2

    Topics: Acromegaly; Adult; Blood Glucose; Bromocriptine; Calcium; Drug Evaluation; Ergolines; Female; Glycos

1977
Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Aged; Biopsy; Collagen; Female; Humans; Hydroxyproline; Male; Middle

1979
[Diagnostic effectiveness of tests on the biochemical activity in acromegaly as evaluated by discrimination analysis].
    Vnitrni lekarstvi, 1978, Volume: 24, Issue:7

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Female; Growth Hormone; Humans; Hydroxyproline; Male;

1978
Urinary hydroxyproline excretion in acromegaly.
    Acta endocrinologica, 1978, Volume: 89, Issue:3

    Topics: Acromegaly; Adult; Circadian Rhythm; Collagen; Creatinine; Fasting; Female; Growth Hormone; Humans;

1978
A simple procedure for the determination of hydroxyproline in urine and bone.
    Biochemical medicine, 1978, Volume: 20, Issue:1

    Topics: Acromegaly; Adult; Animals; Bone and Bones; Colorimetry; Female; Femur; Humans; Hydroxyproline; Hypo

1978
[Plasma hydroxyproline determination in patients with metabolic diseases of the bone collagen].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Acromegaly; Adult; Chronic Kidney Disease-Mineral and Bone Disorder; Humans; Hydroxyproline; Hyperpa

1978
Successful treatment of acromegaly with bromocriptine.
    Postgraduate medical journal, 1976, Volume: 52suppl 1

    Topics: Acromegaly; Bromocriptine; Ergolines; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hydrox

1976
Bromocriptine treatment of acromegaly.
    British medical journal, 1975, Feb-08, Volume: 1, Issue:5953

    Topics: Acromegaly; Adult; Aged; Blood Glucose; Bromine; Circadian Rhythm; Ergot Alkaloids; Female; Glucagon

1975
Treatment of acromegaly by transsphenoidal hypophysectomy with cryoapplication.
    Clinical endocrinology, 1975, Volume: 4, Issue:1

    Topics: Acromegaly; Adrenal Insufficiency; Adult; Calcium; Cerebrospinal Fluid Rhinorrhea; Cryosurgery; Diab

1975
[Urinary excretion of hydroxyproline in acromegaly (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, May-28, Volume: 101, Issue:22

    Topics: Acromegaly; Adult; Aged; Calcium; Female; Humans; Hydroxyproline; Male; Middle Aged; Phosphates

1976
[Proceedings: Significance of hydroxyproline determination in 24-hour urine].
    MMW, Munchener medizinische Wochenschrift, 1974, May-31, Volume: 116, Issue:22

    Topics: Acromegaly; Age Factors; Collagen; Humans; Hydroxyproline; Hyperparathyroidism; Hyperthyroidism; Met

1974
Acromegaly pre- and postpituitary irradiation.
    Metabolism: clinical and experimental, 1966, Volume: 15, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adrenocorticotropic Hormone; Adult; Biopsy;

1966
A trial of medroxyprogesterone acetate in acromegaly.
    Clinical endocrinology, 1972, Volume: 1, Issue:2

    Topics: Acromegaly; Fasting; Glucose Tolerance Test; Growth Hormone; Humans; Hydroxyproline; Male; Medroxypr

1972
[Automated determination of free and combined hydroxyproline].
    Studii si cercetari de endocrinologie, 1972, Volume: 23, Issue:5

    Topics: Acromegaly; Autoanalysis; Colorimetry; Humans; Hydroxyproline; Marfan Syndrome

1972
[Collagen in endocrine diseases with bone involvement].
    Studii si cercetari de endocrinologie, 1973, Volume: 24, Issue:6

    Topics: Acromegaly; Bone and Bones; Bone Diseases; Collagen; Collagen Diseases; Dwarfism, Pituitary; Endocri

1973
Idiopathic gingival hyperplasia and hypertrichosis associated with acromegaloid features.
    Helvetica paediatrica acta, 1973, Volume: 28, Issue:5

    Topics: Abnormalities, Multiple; Acromegaly; Adolescent; Cephalometry; Child; Child, Preschool; Connective T

1973
Insulin deficiency associated with hypoglycemia and good glucose tolerance in hypopituitarism. Report of a case with acromegaly developing pituitary apoplexy.
    Acta medica Scandinavica, 1974, Volume: 195, Issue:5

    Topics: Acromegaly; Aged; Blood Glucose; Cerebrovascular Disorders; Female; Glucose Tolerance Test; Growth H

1974
Nondialyzable urinary hydroxyproline as an index of bone collagen formation.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:3

    Topics: Acromegaly; Adolescent; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Bone Resorption; Calciton

1970
Suppression of growth hormone-dependent human serum sulfation factor by estrogen.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: Acromegaly; Animals; Blood Proteins; Calcium; Cartilage; Depression, Chemical; Drug Antagonism; Estr

1972
[Study of urinary hydroxyproline in osteopathies].
    Pathologie et biologie, 1966, Volume: 14, Issue:21

    Topics: Acromegaly; Adult; Aged; Bone Neoplasms; Female; Humans; Hydroxyproline; Hyperparathyroidism; Hypert

1966
[Urinary hydroxyproline and the metabolism of collagen].
    Duodecim; laaketieteellinen aikakauskirja, 1969, Volume: 85, Issue:18

    Topics: Acromegaly; Bone Diseases; Child; Collagen; Collagen Diseases; Dwarfism, Pituitary; Humans; Hydroxyp

1969
The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1970, Volume: 27, Issue:3

    Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Bone Diseases; Cholest

1970
[Urinary hydroxyproline and circulating HGH. (Preliminary findings in some endocrine diseases)].
    Folia endocrinologica, 1967, Volume: 20, Issue:4

    Topics: Acromegaly; Adolescent; Adult; Aged; Child; Diabetes Mellitus; Female; Gonadotropins; Growth Hormone

1967
Influence of estradiol and estriol on urinary excretion of hydroxyproline in man.
    The Journal of laboratory and clinical medicine, 1968, Volume: 71, Issue:1

    Topics: Acromegaly; Adult; Aged; Breast Neoplasms; Creatinine; Estradiol; Estriol; Estrogens; Female; Growth

1968
Renal tubular transport of hydroxyproline peptides: evidence for reabsorption and secretion.
    Metabolism: clinical and experimental, 1968, Volume: 17, Issue:1

    Topics: Absorption; Acromegaly; Adult; Chromatography; Diet; Gelatin; Glomerular Filtration Rate; Humans; Hy

1968
[Hydroxyproline in various diseases of the endocrine system].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Dec-16, Volume: 23, Issue:51

    Topics: Acromegaly; Adult; Aged; Female; Humans; Hydroxyproline; Hypoparathyroidism; Male; Middle Aged; Thyr

1968
Mechanism of estrogenic action in acromegaly.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:2

    Topics: Acromegaly; Adult; Blood Glucose; Calcium; Calcium Isotopes; Calcium, Dietary; Diet; Ethinyl Estradi

1969
Effects of calcium infusion on urinary hydroxyproline and phosphorus: evaluation as a diagnostic test.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:7

    Topics: Acromegaly; Adolescent; Adult; Aged; Calcium; Child; Female; Humans; Hydroxyproline; Hypercalcemia;

1966