hydroxyproline has been researched along with Hypertension, Pulmonary in 22 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pulmonary hydroxyproline content (HPC), pulmonary connective tissue growth factor (CTGF) transcription and lung compliance (LC) were analysed to characterize pulmonary fibrosis." | 7.79 | Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats. ( Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R, 2013) |
| "A polymeric prodrug of the proline analogue cis-4-hydroxy-l-proline (CHOP), poly(ethylene glycol)-lysine-CHOP or CHOP-PEG, prevents hypoxic pulmonary hypertension in rats by inhibiting collagen accumulation." | 7.73 | Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats. ( Belinka, B; Lu, SE; Pachence, J; Poiani, GJ; Riley, DJ; Simon, PM; Tozzi, CA, 2006) |
| "To determine whether all-trans retinoic acid (atRA) exerts an inhibitory effect on rats with pulmonary hypertension induced by monocrotaline." | 7.71 | All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline. ( Ben, X; Li, F; Liang, Y; Qin, Y; Shen, J; Zhou, A, 2001) |
| " Pulmonary hydroxyproline content (HPC), pulmonary connective tissue growth factor (CTGF) transcription and lung compliance (LC) were analysed to characterize pulmonary fibrosis." | 3.79 | Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats. ( Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R, 2013) |
| "A polymeric prodrug of the proline analogue cis-4-hydroxy-l-proline (CHOP), poly(ethylene glycol)-lysine-CHOP or CHOP-PEG, prevents hypoxic pulmonary hypertension in rats by inhibiting collagen accumulation." | 3.73 | Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats. ( Belinka, B; Lu, SE; Pachence, J; Poiani, GJ; Riley, DJ; Simon, PM; Tozzi, CA, 2006) |
| "To determine whether all-trans retinoic acid (atRA) exerts an inhibitory effect on rats with pulmonary hypertension induced by monocrotaline." | 3.71 | All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline. ( Ben, X; Li, F; Liang, Y; Qin, Y; Shen, J; Zhou, A, 2001) |
| " We determined whether there was a correlation between hydroxyproline content of rat pulmonary artery segments and elastance (EPA) of the pulmonary artery bed during development of hypoxic pulmonary hypertension (10% O2, 10 d) and normoxic recovery." | 3.69 | Excess collagen in hypertensive pulmonary arteries decreases vascular distensibility. ( Christiansen, DL; Poiani, GJ; Riley, DJ; Tozzi, CA, 1994) |
| "Both 764-3 and ligustrazine significantly inhibited the increase of pulmonary arterial pressure and elevation of hydroxyproline content in extrapulmonary arterial wall during chronic hypoxia." | 3.69 | [Effect of 764-3 and ligustrazine on collagen content of extrapulmonary arteries during chronic hypoxia]. ( Chen, X; Sun, R; Yan, Y, 1996) |
| "We recently reported that platelet-activating factor (PAF) levels increased in lung tissue after 1 subcutaneous injection of monocrotaline (MCT) (which causes lung injury), and, further, that treatment with PAF antagonists reduced pulmonary hypertension in this chronic lung injury rat model [15]." | 3.68 | PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model. ( Ono, S; Voelkel, NF, 1992) |
| "Triamcinolone treatment (12 mg/kg intraperitoneally, once daily for 3 days) reduced mean right ventricular pressure (11 +/- 1 versus 14 +/- 1 mm Hg) and protein content of pulmonary arteries (1." | 1.29 | Effect of glucocorticoids on collagen accumulation in pulmonary vascular remodeling in the rat. ( Choe, JK; Poiani, GJ; Riley, DJ; Thakker-Varia, S; Tozzi, CA, 1994) |
| " Dose-response curves to prostaglandin F2 alpha, (PGF2 alpha), angiotensin II (ANG II), and norepinephrine (NE) and responses to a depolarizing concentration of KCl were obtained on rings of pulmonary artery from normal rats, chronically hypoxic (10% O2 for 10 days) rats, and chronically hypoxic rats treated with cis-4-hydroxy-L-proline (cHyp), an agent that blocks collagen accumulation." | 1.28 | Vascular collagen affects reactivity of hypertensive pulmonary arteries of the rat. ( Edelman, NH; Poiani, GJ; Riley, DJ; Tozzi, CA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 12 (54.55) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schroll, S | 1 |
| Lange, TJ | 1 |
| Arzt, M | 1 |
| Sebah, D | 1 |
| Nowrotek, A | 1 |
| Lehmann, H | 1 |
| Wensel, R | 1 |
| Pfeifer, M | 1 |
| Blumberg, FC | 1 |
| Tian, L | 1 |
| Wang, Z | 2 |
| Liu, Y | 1 |
| Eickhoff, JC | 2 |
| Eliceiri, KW | 1 |
| Chesler, NC | 3 |
| Estrada, KD | 1 |
| Ooi, CY | 1 |
| Tabima, DM | 1 |
| Simon, PM | 1 |
| Pachence, J | 1 |
| Belinka, B | 1 |
| Poiani, GJ | 6 |
| Lu, SE | 1 |
| Tozzi, CA | 7 |
| Riley, DJ | 8 |
| McKenzie, JC | 1 |
| Klein, RM | 1 |
| Kerr, JS | 2 |
| Frank, MM | 1 |
| Trelstad, RL | 1 |
| Frankel, HM | 2 |
| Sun, R | 2 |
| Yan, Y | 2 |
| Chen, X | 2 |
| Si, Q | 1 |
| Li, H | 1 |
| Skalski, J | 1 |
| Kortys-Puchalska, E | 1 |
| Komarski, K | 1 |
| Zmuda, A | 1 |
| Wites, M | 1 |
| Bochenek, A | 1 |
| Rokicki, W | 1 |
| Thakker-Varia, S | 1 |
| Choe, JK | 2 |
| Christiansen, DL | 1 |
| Kemnitzer, JE | 1 |
| Fox, JD | 1 |
| Kohn, J | 1 |
| Pelouch, V | 1 |
| Kolár, F | 1 |
| Ost'ádal, B | 1 |
| Milerová, M | 1 |
| Cihák, R | 1 |
| Widimský, J | 1 |
| Berg, JT | 1 |
| Breen, EC | 1 |
| Fu, Z | 1 |
| Mathieu-Costello, O | 1 |
| West, JB | 1 |
| Liu, Z | 1 |
| Cheng, X | 1 |
| Cai, R | 1 |
| Sun, B | 1 |
| Zhu, Y | 1 |
| Qin, Y | 1 |
| Zhou, A | 1 |
| Ben, X | 1 |
| Shen, J | 1 |
| Liang, Y | 1 |
| Li, F | 1 |
| Ono, S | 1 |
| Voelkel, NF | 1 |
| Bishop, JE | 1 |
| Guerreiro, D | 1 |
| Laurent, GJ | 1 |
| Yohn, SE | 1 |
| Edelman, NH | 1 |
| Ruppert, CL | 1 |
| Neubauer, JA | 1 |
| Yu, SY | 1 |
22 other studies available for hydroxyproline and Hypertension, Pulmonary
| Article | Year |
|---|---|
Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.
Topics: Animals; Bleomycin; Hydroxyproline; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung Co | 2013 |
Validation of an arterial constitutive model accounting for collagen content and crosslinking.
Topics: Aminopropionitrile; Animals; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Elasticity; | 2016 |
Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia.
Topics: Animals; Biomechanical Phenomena; Collagen; Extracellular Matrix; Gene Expression Profiling; Gene Ex | 2009 |
The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension.
Topics: Animals; Biomechanical Phenomena; Blood Pressure; Chronic Disease; Collagen Type I; Collagen Type I, | 2010 |
Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hydroxyproline; Hypertension, Pulmonary; | 2006 |
Protein synthesis in the rat pulmonary trunk during the early development of hypoxia-induced pulmonary hypertension.
Topics: Animals; Cardiomegaly; Collagen; Glycine; Hematocrit; Hydroxyproline; Hypertension, Pulmonary; Hypox | 1983 |
Reduction of chronic hypoxic pulmonary hypertension in the rat by beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Body Weight; Chronic Disease; Heart Ventricles; Hematocrit; Hemodynamic | 1984 |
Role of collagen metabolism changes in the pathogenesis of pulmonary hypertension in rats and its reversibility.
Topics: Animals; Blood Pressure; Collagen; Drugs, Chinese Herbal; Hydroxyproline; Hypertension, Pulmonary; H | 1994 |
[Hydroxyproline in serum and urine in children with pulmonary hypertension in the course of congenital heart defects].
Topics: Child; Child, Preschool; Collagen; Heart Defects, Congenital; Humans; Hydroxyproline; Hypertension, | 1994 |
Effect of glucocorticoids on collagen accumulation in pulmonary vascular remodeling in the rat.
Topics: Analysis of Variance; Animals; Collagen; Dose-Response Relationship, Drug; Hemodynamics; Hydroxyprol | 1994 |
Excess collagen in hypertensive pulmonary arteries decreases vascular distensibility.
Topics: Animals; Collagen; Elasticity; Hydroxyproline; Hypertension, Pulmonary; In Vitro Techniques; Male; P | 1994 |
Polymeric carrier of proline analogue with antifibrotic effect in pulmonary vascular remodeling.
Topics: Amylopectin; Animals; Cells, Cultured; Collagen; Drug Carriers; Endothelium, Vascular; Hydroxyprolin | 1997 |
Regression of chronic hypoxia-induced pulmonary hypertension, right ventricular hypertrophy, and fibrosis: effect of enalapril.
Topics: Altitude Sickness; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chronic Disease; | 1997 |
[Effect of 764-3 and ligustrazine on collagen content of extrapulmonary arteries during chronic hypoxia].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Drugs, Chinese Herbal; Hydroxyproline; H | 1996 |
Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor-B in lung parenchyma.
Topics: Analysis of Variance; Animals; Blood Pressure; Body Weight; Capillaries; Collagen; Endothelial Growt | 1998 |
[Effects of 764-3 on collagen deposition in hypertensive pulmonary arteries in hypoxic rats].
Topics: Aminopropionitrile; Animals; Collagen; Drugs, Chinese Herbal; Hydroxyproline; Hypertension, Pulmonar | 1998 |
All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline.
Topics: Animals; Blood Pressure; Hydroxyproline; Hypertension, Pulmonary; Lung; Male; Matrix Metalloproteina | 2001 |
PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model.
Topics: Animals; Azepines; Blood Pressure; Hydroxyproline; Hypertension, Pulmonary; Lung; Male; Monocrotalin | 1992 |
Changes in the composition and metabolism of arterial collagens during the development of pulmonary hypertension in rabbits.
Topics: Animals; Aorta; Bleomycin; Collagen; Electrophoresis, Polyacrylamide Gel; Hydroxyproline; Hypertensi | 1990 |
An antifibrotic agent reduces blood pressure in established pulmonary hypertension in the rat.
Topics: Animals; Arterioles; Blood Viscosity; Collagen; Hematocrit; Hemodynamics; Hydroxyproline; Hypertensi | 1990 |
Vascular collagen affects reactivity of hypertensive pulmonary arteries of the rat.
Topics: Angiotensin II; Animals; Collagen; Dinoprost; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Male | 1989 |
Reduction of chronic hypoxic pulmonary hypertension in the rat by an inhibitor of collagen production.
Topics: Animals; Arterioles; Cardiac Output; Chronic Disease; Collagen; Heart Ventricles; Hematocrit; Hydrox | 1987 |