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hydroxyproline and Hyperoxaluria

hydroxyproline has been researched along with Hyperoxaluria in 18 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Hyperoxaluria: Excretion of an excessive amount of OXALATES in the urine.

Research Excerpts

ExcerptRelevanceReference
"In the present study, it is investigated whether restriction of dietary vitamin B2 (VB2) can reduce hepatic GO activity and oxalate excretion in mice with hyperoxaluria induce by hydroxyproline (Hyp) or obesity."8.02Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice. ( Mawatari, K; Shimohata, T; Suyama, M; Takahashi, A; Uebanso, T, 2021)
"Hydroxyproline (Hyp) metabolism is a key source of glyoxylate production in the body and may be a major contributor to excessive oxalate production in the primary hyperoxalurias where glyoxylate metabolism is impaired."7.78Metabolism of [13C5]hydroxyproline in vitro and in vivo: implications for primary hyperoxaluria. ( Callahan, MF; Holmes, RP; Jiang, J; Johnson, LC; Knight, J; Lowther, WT; Riedel, TJ, 2012)
"The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate."7.77Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011)
" In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP)."7.76Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model. ( Crenshaw, TD; Darriet, C; Kaplon, DM; Nakada, SY; Penniston, KL, 2010)
"Rats receiving hydroxy-L-proline showed hyperoxaluria, calcium oxalate crystalluria and nephrolithiasis, and by day 42 all contained renal calcium oxalate crystal deposits."7.74Dietary oxalate and calcium oxalate nephrolithiasis. ( Byer, KJ; Glenton, PA; Khan, SR, 2007)
"Hyperoxaluria was induced in male Sprague-Dawley rats by feeding hydroxyl-L-proline."5.40Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys. ( Khan, A; Khan, SR; Wang, W, 2014)
"Primary hyperoxaluria type 1 (PH1) and type 2 (PH2) are rare genetic diseases that result from deficiencies in glyoxylate metabolism."5.38Hydroxyproline metabolism in mouse models of primary hyperoxaluria. ( Cramer, SD; Holmes, RP; Knight, J; Salido, E; Takayama, T, 2012)
"Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis."5.33Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006)
" We used rats fed a high-fat diet (HFD) to achieve hyperlipidemia (HL) and hydroxyproline (HP) water to establish a hyperoxaluric CaOx nephrolithiasis model; the animals were administered statins (A) for 28 days."4.12Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet. ( Huang, HS; Liu, CJ; Tsai, YS, 2022)
"In the present study, it is investigated whether restriction of dietary vitamin B2 (VB2) can reduce hepatic GO activity and oxalate excretion in mice with hyperoxaluria induce by hydroxyproline (Hyp) or obesity."4.02Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice. ( Mawatari, K; Shimohata, T; Suyama, M; Takahashi, A; Uebanso, T, 2021)
"We previously reported hyperoxaluria and calcium oxalate calculi in adult pigs (sows) fed hydroxyproline (HP)."3.79Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model. ( Crenshaw, TD; Nakada, SY; Penniston, KL; Sehgal, PD; Sivalingam, S, 2013)
"The purpose of our study was to determine if a hydroxyproline (HP) or gelatin diet could induce long-term hyperoxaluria in the porcine model."3.78Dietary induction of long-term hyperoxaluria in the porcine model. ( Crenshaw, TD; Iwicki, L; Nakada, SY; Patel, SR; Penniston, KL; Saeed, I, 2012)
"The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate."3.77Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011)
" In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP)."3.76Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model. ( Crenshaw, TD; Darriet, C; Kaplon, DM; Nakada, SY; Penniston, KL, 2010)
" Hyperoxaluria was induced by adding hydroxyproline (HP) to the drinking water."3.75Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains. ( Garrett, MR; Mandel, NS; Roman, RJ; Wiessner, JH, 2009)
"Rats receiving hydroxy-L-proline showed hyperoxaluria, calcium oxalate crystalluria and nephrolithiasis, and by day 42 all contained renal calcium oxalate crystal deposits."3.74Dietary oxalate and calcium oxalate nephrolithiasis. ( Byer, KJ; Glenton, PA; Khan, SR, 2007)
"Hyperoxaluria induces crystalluria, interstitial fibrosis, and progressive renal failure."1.46Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury. ( Borges, FT; Convento, MB; Cruz, E; da Glória, MA; Pessoa, EA; Schor, N, 2017)
"HS did not affect the hyperoxaluria, hypocalciuria or supersaturation caused by HP; however, it increased calcium oxalate crystal deposition soon after 7 days of co-treatment."1.42High Sodium-Induced Oxidative Stress and Poor Anticrystallization Defense Aggravate Calcium Oxalate Crystal Formation in Rat Hyperoxaluric Kidneys. ( Huang, HS; Ma, MC, 2015)
"Hyperoxaluria was induced in male Sprague-Dawley rats by feeding hydroxyl-L-proline."1.40Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys. ( Khan, A; Khan, SR; Wang, W, 2014)
"Primary hyperoxaluria type 1 (PH1) and type 2 (PH2) are rare genetic diseases that result from deficiencies in glyoxylate metabolism."1.38Hydroxyproline metabolism in mouse models of primary hyperoxaluria. ( Cramer, SD; Holmes, RP; Knight, J; Salido, E; Takayama, T, 2012)
"Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis."1.33Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's11 (61.11)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Liu, CJ1
Tsai, YS1
Huang, HS3
Assimos, DG1
Uebanso, T1
Suyama, M1
Shimohata, T1
Mawatari, K1
Takahashi, A1
Convento, MB1
Pessoa, EA1
Cruz, E1
da Glória, MA1
Schor, N1
Borges, FT1
Khan, A2
Wang, W2
Khan, SR5
Sivalingam, S1
Nakada, SY3
Sehgal, PD1
Crenshaw, TD3
Penniston, KL3
Joshi, S1
Peck, AB1
Ma, MC2
Wiessner, JH2
Garrett, MR2
Roman, RJ1
Mandel, NS2
Kaplon, DM1
Darriet, C1
Hung, LY1
Wille, DF1
Zuo, J1
Glenton, PA3
Patel, SR1
Iwicki, L1
Saeed, I1
Knight, J2
Holmes, RP2
Cramer, SD1
Takayama, T1
Salido, E1
Jiang, J1
Johnson, LC1
Callahan, MF1
Riedel, TJ1
Lowther, WT1
Byer, KJ2
Chen, J1

Other Studies

18 other studies available for hydroxyproline and Hyperoxaluria

ArticleYear
Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet.
    International journal of molecular sciences, 2022, Mar-11, Volume: 23, Issue:6

    Topics: Animals; Atorvastatin; Calcium; Calcium Oxalate; Diet, High-Fat; Hydroxymethylglutaryl-CoA Reductase

2022
Re: The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria.
    The Journal of urology, 2020, Volume: 203, Issue:5

    Topics: Animals; Glycolates; Hydroxyproline; Hyperoxaluria; Hyperoxaluria, Primary; Mice; Oxalates; Oxidored

2020
Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:15

    Topics: Alcohol Oxidoreductases; Animals; Creatinine; Diet; Hydroxyproline; Hyperoxaluria; Kidney; Male; Mic

2021
Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury.
    Scientific reports, 2017, 04-07, Volume: 7

    Topics: Animals; Calcium Oxalate; Cell Movement; Epithelial-Mesenchymal Transition; Ethylene Glycol; Fibrosi

2017
Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys.
    World journal of urology, 2014, Volume: 32, Issue:1

    Topics: Animals; Calcium Oxalate; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Dogs; D

2014
Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model.
    Journal of endourology, 2013, Volume: 27, Issue:12

    Topics: Animal Feed; Animals; Calcium Oxalate; Diet; Disease Models, Animal; Female; Hydroxyproline; Hyperox

2013
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.
    American journal of physiology. Renal physiology, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Acetophenones; Animals; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hyperoxal

2014
High Sodium-Induced Oxidative Stress and Poor Anticrystallization Defense Aggravate Calcium Oxalate Crystal Formation in Rat Hyperoxaluric Kidneys.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Animals; Antioxidants; Biomarkers; Calcium Oxalate; Citrates; Creatinine; Crystallization; Dicarboxy

2015
Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:2

    Topics: Animals; Animals, Congenic; Calcium Oxalate; Chromosomes, Mammalian; Disease Models, Animal; Genetic

2009
Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model.
    Journal of endourology, 2010, Volume: 24, Issue:3

    Topics: Acids; Animals; Diet; Disease Models, Animal; Female; Glycolates; Hydrogen-Ion Concentration; Hydrox

2010
Improved methodology to induce hyperoxaluria without treatment using hydroxyproline.
    Urological research, 2011, Volume: 39, Issue:5

    Topics: Animals; Crystallization; Disease Models, Animal; Hydroxyproline; Hyperoxaluria; Kidney; Male; Oxali

2011
Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:6

    Topics: Animals; Blotting, Western; Calcium Oxalate; Cell Adhesion Molecules; Chemokine CCL2; Hydroxyproline

2011
Dietary induction of long-term hyperoxaluria in the porcine model.
    Journal of endourology, 2012, Volume: 26, Issue:5

    Topics: Animals; Catheterization; Diet; Disease Models, Animal; Gelatin; Hydroxyproline; Hyperoxaluria; Oxal

2012
Hydroxyproline metabolism in mouse models of primary hyperoxaluria.
    American journal of physiology. Renal physiology, 2012, Mar-15, Volume: 302, Issue:6

    Topics: Alcohol Oxidoreductases; Animal Feed; Animals; Diet; Hydroxyproline; Hyperoxaluria; Male; Mice; Mice

2012
Metabolism of [13C5]hydroxyproline in vitro and in vivo: implications for primary hyperoxaluria.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Mar-15, Volume: 302, Issue:6

    Topics: Alcohol Oxidoreductases; Animals; Carbon Isotopes; Gene Expression Regulation; Hep G2 Cells; Humans;

2012
Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline.
    Kidney international, 2006, Volume: 70, Issue:5

    Topics: Animals; Calcium; Calcium Oxalate; Creatinine; Dinoprost; Disease Models, Animal; Gene Expression Re

2006
Dietary oxalate and calcium oxalate nephrolithiasis.
    The Journal of urology, 2007, Volume: 178, Issue:5

    Topics: Animals; Calcium Oxalate; Creatinine; Dietary Supplements; Disease Models, Animal; Follow-Up Studies

2007
Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; Arginine; Calcium Oxalate; Crystallization; Disease Models, Animal; Dose-Response Relations

2008