hydroxyproline has been researched along with Granuloma in 118 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using a model hepatic collagen synthesizing system, freshly isolated granulomas derived from mouse livers after 8 weeks of infection with Schistosoma mansoni, incubation over a period of 7 days with [14C]proline to measure collagen production, demonstrated a reduction in acid-precipitable [14C]hydroxyproline per milligram DNA in granuloma cultures incubated with 2-aminoethyl cysteine compared to control cultures, and the effect was dose-related." | 7.66 | Effect of 2-aminoethyl-L-cysteine on collagen accumulation in isolated hepatic granulomas. ( Wu, CH; Wu, GY, 1983) |
| "Mice treated with praziquantel showed a prompt decrease in S." | 5.27 | Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis. ( Dunn, MA; Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1985) |
| " The granuloma area, hepatic hydroxyproline (HYP) level and hepatic fibrosis of the protein therapeutic groups were significantly smaller than those of the positive control group (P<0." | 3.80 | The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease. ( Chu, D; Yao, Y; Zhou, C, 2014) |
| " Fibrosis was associated with formation of granulomas, increase in lung hydroxyproline, and sustained increases in tissue tumor necrosis factor-alpha and transforming growth factor-beta." | 3.70 | Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses. ( Franco, L; Gomez, BL; Graybill, JR; Najvar, L; Restrepo, A; Restrepo, S, 1998) |
| "Diclofenac had no significant effect on GAG or hydroxyproline content of implanted cartilage or on granuloma cytokine concentrations." | 3.70 | Effects of diacerhein on granuloma induced cartilage breakdown in the mouse. ( Alam, CA; Greenslade, KJ; Moore, AR; Willoughby, DA, 1998) |
| "Oxaceprol, an established therapeutic agent for osteoarthritis, had no effect on macrophage prostaglandin E2 release in vitro and inhibited carrageenan paw oedema at high doses (18-150 mg/kg p." | 3.69 | Oxaceprol, an atypical inhibitor of inflammation and joint damage. ( Brune, K; Ionac, M; Parnham, MJ; Plauchithiu, M, 1996) |
| " To test this hypothesis, we used a granuloma pouch model, where a subcutaneous air sac is created followed by injection of croton oil." | 3.69 | Fibrous tissue and angiotensin II. ( Ganjam, VK; Ramires, FJ; Sun, Y; Weber, KT; Zhou, G, 1997) |
| " The effect of one such angiostatic treatment, cortisone combined with heparin, was tested in an in vivo model of granuloma-mediated cartilage degradation." | 3.68 | The use of angiostatic steroids to inhibit cartilage destruction in an in vivo model of granuloma-mediated cartilage degradation. ( Colville-Nash, PR; el-Ghazaly, M; Willoughby, DA, 1993) |
| " All mice were killed 4 weeks after wounding, and wound breaking strength and hydroxyproline content of the sponge granulomas were measured." | 3.67 | Inhibition of wound repair by thymic hormones. ( Barbul, A; Efron, JE; Frankel, HL; Shawe, T; Wasserkrug, HL, 1989) |
| " Using a model hepatic collagen synthesizing system, freshly isolated granulomas derived from mouse livers after 8 weeks of infection with Schistosoma mansoni, incubation over a period of 7 days with [14C]proline to measure collagen production, demonstrated a reduction in acid-precipitable [14C]hydroxyproline per milligram DNA in granuloma cultures incubated with 2-aminoethyl cysteine compared to control cultures, and the effect was dose-related." | 3.66 | Effect of 2-aminoethyl-L-cysteine on collagen accumulation in isolated hepatic granulomas. ( Wu, CH; Wu, GY, 1983) |
| " in rats, inhibited hydroxyproline and total protein accumulation, without altering relative amounts of collagen, when administered early during granuloma development." | 3.66 | Collagen metabolism and phenotype after prostaglandin E2 treatment of granuloma: direct and macrophage-modulated effects. ( Bonta, IL; Parnham, MJ; Schoenmaker, H; Shoshan, S, 1982) |
| " Arginine-deficient rats also showed decreased collagen deposition in a specific wound site, as indicated by the decreased content in hydroxyproline in sponge granulomas (2." | 3.66 | Arginine: an essential amino acid for injured rats. ( Barbul, A; Levenson, SM; Rettura, G; Seifter, E, 1978) |
| " Collagen synthesis, as measured by the formation of labeled protein-bound hydroxyproline, occurred in granulomas isolated from fibrotic livers." | 3.65 | Liver collagen synthesis in murine schistosomiasis. ( Dunn, MA; Hait, PK; Rifas, L; Rojkind, M; Seifter, S; Warren, KS, 1977) |
| " Subcutaneous inflammatory granuloma were induced in young rats and the urinary excretion of hydroxyproline and hydroxylysyl glycosides was observed during the period of acute inflammation." | 3.65 | Urinary excretion of hydroxylysyl glycosides during acute inflammation in the rat. ( Askenasi, R; Bazin, S; Le Lous, M; Rao, VH, 1976) |
| "In BALB/c mice, as in man, progressive pulmonary tuberculosis is accompanied by increasing expression of IL-4." | 1.32 | Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. ( Aguilar, D; Hernandez, ML; Hernandez-Pando, R; Orozco, H; Rook, G, 2004) |
| "Hepatic silicosis was induced in rats by an intravenous injection of saline-suspended silica, 40 mg/kg of body weight." | 1.27 | Formation of granulomas in liver of silica-treated rats. ( Bartoś, F; Horský, J; Kanta, J; Korolenko, TA; Kovárová, H; Tilser, I, 1986) |
| "Mice treated with praziquantel showed a prompt decrease in S." | 1.27 | Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis. ( Dunn, MA; Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1985) |
| "2." | 1.25 | Amino acid metabolism of experimental granulation tissue in vitro. ( Aalto, M; Kulonen, E; Lampiaho, K; Pikkarainen, J, 1973) |
| "The effects of estradiol-17beta on total body collagen metabolism were studied in adult female guinea pigs in which all collagen had been prelabelled by the chronic administration of -Lproline during the period of rapid growth." | 1.25 | Effect of estradiol-17 on collagen biosynthesis, degradation and re-utilization in vivo. ( Henneman, DH, 1971) |
| "Hydroxyproline and proline were isolated by chromatography on paper from hydrolysates of the nuclear, mitochondrial, and microsomal collagen fractions, after incubation of tissue slices with L-(14)C-proline." | 1.24 | Morphological and chemical studies of collagen formation. II. Metabolic activity of collagen associated with subcellular fractions of guinea pig granulomata. ( CHAPMAN, JA; GREEN, NM; LOWTHER, DA, 1961) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (79.66) | 18.7374 |
| 1990's | 14 (11.86) | 18.2507 |
| 2000's | 4 (3.39) | 29.6817 |
| 2010's | 6 (5.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shkurupiy, VA | 2 |
| Kim, LB | 4 |
| Nikonova, IK | 3 |
| Potapova, OV | 3 |
| Cherdantseva, LA | 2 |
| Sharkova, TV | 2 |
| Yao, Y | 1 |
| Zhou, C | 1 |
| Chu, D | 1 |
| Putyatina, AN | 3 |
| Shkurupii, VA | 1 |
| Shkurupy, VA | 1 |
| El-Lakkany, NM | 1 |
| El-Maadawy, W | 1 |
| Ain-Shoka, A | 1 |
| Badawy, A | 1 |
| Hammam, O | 1 |
| Ebeid, F | 1 |
| VAN ROBERTSON, WB | 1 |
| HIWETT, J | 1 |
| HERMAN, C | 1 |
| LOWTHER, DA | 1 |
| GREEN, NM | 1 |
| CHAPMAN, JA | 1 |
| CHVAPIL, M | 10 |
| CMUCHALOVA, B | 2 |
| TRNAVSKY, K | 7 |
| TRNAVSKA, Z | 4 |
| MALINSKY, J | 3 |
| ISOMAEKI, H | 1 |
| KULONEN, E | 8 |
| NOCENTI, MR | 1 |
| LEDERMAN, GE | 1 |
| FUREY, CA | 1 |
| LOPANO, AJ | 1 |
| KONNO, K | 1 |
| TETSUKA, T | 1 |
| KOBRLE, V | 1 |
| Hernandez-Pando, R | 1 |
| Aguilar, D | 1 |
| Hernandez, ML | 1 |
| Orozco, H | 1 |
| Rook, G | 1 |
| Boros, DL | 2 |
| Singh, KP | 1 |
| Gerard, HC | 1 |
| Hudson, AP | 1 |
| White, SL | 1 |
| Cutroneo, KR | 3 |
| Bole, GG | 1 |
| Heath, LE | 1 |
| Kumento, A | 1 |
| Lampiaho, K | 2 |
| Lapárová, V | 1 |
| Parnham, MJ | 3 |
| Shoshan, S | 4 |
| Schoenmaker, H | 2 |
| Bonta, IL | 2 |
| Peacock, EE | 3 |
| Carlson, EC | 2 |
| Blau, S | 1 |
| Steinbronn, K | 1 |
| Morton, D | 1 |
| Wu, GY | 1 |
| Wu, CH | 1 |
| Cheever, AW | 2 |
| Duvall, RH | 1 |
| Hallack, TA | 1 |
| Reiser, KM | 1 |
| Hesterberg, TW | 1 |
| Haschek, WM | 1 |
| Last, JA | 1 |
| Dayan, D | 1 |
| Benveniste, K | 1 |
| Thut, P | 1 |
| Lande, MA | 1 |
| Carrick, L | 1 |
| Denis, M | 1 |
| Bisson, D | 1 |
| Kubo, M | 1 |
| Asano, T | 1 |
| Shiomoto, H | 1 |
| Matsuda, H | 1 |
| Andrade, ZA | 1 |
| Cox, TM | 1 |
| Cheever, AM | 1 |
| Colville-Nash, PR | 1 |
| el-Ghazaly, M | 1 |
| Willoughby, DA | 3 |
| Ionac, M | 1 |
| Plauchithiu, M | 1 |
| Brune, K | 1 |
| Meisler, N | 1 |
| Keefer, KA | 1 |
| Ehrlich, HP | 1 |
| Yager, DR | 1 |
| Myers-Parrelli, J | 1 |
| Sun, Y | 1 |
| Ramires, FJ | 1 |
| Zhou, G | 1 |
| Ganjam, VK | 1 |
| Weber, KT | 1 |
| Moore, AR | 2 |
| Greenslade, KJ | 2 |
| Alam, CA | 2 |
| Or, R | 1 |
| Feferman, R | 1 |
| Franco, L | 1 |
| Najvar, L | 1 |
| Gomez, BL | 1 |
| Restrepo, S | 1 |
| Graybill, JR | 1 |
| Restrepo, A | 1 |
| Lao, I | 1 |
| Wojtczak, J | 1 |
| Krajnow, A | 1 |
| Potter, JJ | 1 |
| Mezey, E | 1 |
| Barnes, MJ | 2 |
| Wehr, RF | 1 |
| Smith, JG | 1 |
| Counts, DF | 1 |
| Langness, U | 1 |
| Nissen, R | 1 |
| Seifter, E | 2 |
| Rettura, G | 2 |
| Barbul, A | 2 |
| Levenson, SM | 2 |
| Bazin, S | 2 |
| Briquelet, N | 1 |
| Allain, JC | 1 |
| Delaunay, A | 1 |
| Dunn, MA | 2 |
| Rojkind, M | 1 |
| Warren, KS | 1 |
| Hait, PK | 1 |
| Rifas, L | 1 |
| Seifter, S | 1 |
| Ohuchi, K | 1 |
| Sato, H | 1 |
| Tsurufuji, S | 4 |
| Potila, M | 1 |
| Hansen, TM | 1 |
| Lorenzen, I | 2 |
| Askenasi, R | 1 |
| Le Lous, M | 1 |
| Rao, VH | 1 |
| Lee, KH | 3 |
| Fu, CC | 2 |
| Jung, M | 1 |
| Nawar, O | 1 |
| Akridge, RE | 1 |
| Hassan, E | 1 |
| el Gazar, R | 1 |
| Doughty, BL | 1 |
| Kemp, WM | 1 |
| Van Gool, J | 1 |
| Van Tiel, D | 1 |
| Doenhoff, MJ | 1 |
| Van Vugt, H | 1 |
| Oda, D | 1 |
| Gown, AM | 1 |
| Vande Berg, JS | 1 |
| Stern, R | 1 |
| Amemiya, K | 2 |
| Suzuki, J | 2 |
| Kimura, M | 2 |
| Nováková, O | 1 |
| Musil, J | 2 |
| Shawe, T | 1 |
| Frankel, HL | 1 |
| Efron, JE | 1 |
| Wasserkrug, HL | 1 |
| Kubota, Y | 1 |
| Fujiwara, K | 1 |
| Ogata, I | 1 |
| Hori, Y | 1 |
| Oka, H | 1 |
| Hørslev-Petersen, K | 1 |
| Kim, KY | 1 |
| Pedersen, LR | 1 |
| Bentsen, KD | 1 |
| Uldbjerg, N | 1 |
| Oxlund, H | 1 |
| Garbarsch, C | 1 |
| Hahn, EG | 1 |
| Schuppan, D | 1 |
| Kanta, J | 1 |
| Horský, J | 1 |
| Kovárová, H | 1 |
| Tilser, I | 1 |
| Korolenko, TA | 1 |
| Bartoś, F | 1 |
| Bowers, RR | 1 |
| Birch, ML | 1 |
| Thomas, DW | 2 |
| Nishimura, M | 1 |
| Asahi, M | 1 |
| Hayashi, M | 1 |
| Takazono, I | 1 |
| Tanaka, Y | 1 |
| Kohda, H | 1 |
| Urabe, H | 1 |
| Morcos, SH | 1 |
| Khayyal, MT | 1 |
| Mansour, MM | 1 |
| Saleh, S | 1 |
| Ishak, EA | 1 |
| Girgis, NI | 1 |
| Barral-Netto, M | 1 |
| Gries, G | 1 |
| Lindner, J | 1 |
| Kirchheiner, B | 1 |
| Németh-Csóka, M | 2 |
| Rokosova, B | 1 |
| Gottlieb, AA | 1 |
| Kaplan, A | 1 |
| Udenfriend, S | 3 |
| Hutton, JJ | 1 |
| Miller, RL | 1 |
| Rajamäki, A | 1 |
| Kodicek, E | 1 |
| Stancíková, M | 1 |
| McCarthy, D | 1 |
| Madden, JW | 2 |
| Prasad, CU | 1 |
| Bose, SM | 1 |
| Shubin, JA | 1 |
| Starr, P | 1 |
| Suzuki, Y | 1 |
| Ito, M | 1 |
| Hamaguchi, Y | 1 |
| Yamagami, I | 1 |
| Rantanen, J | 1 |
| Aalto, M | 2 |
| Fukuhara, M | 3 |
| Nakagawa, H | 2 |
| Spencer, MR | 1 |
| Tong, TG | 2 |
| Poon, R | 1 |
| Pikkarainen, J | 1 |
| Jackson, SH | 3 |
| Heininger, JA | 3 |
| Robert, AM | 1 |
| Ouzilou, J | 1 |
| Robert, L | 1 |
| Stassen, FL | 1 |
| Kuyper, CM | 1 |
| Henneman, DH | 4 |
| Brown, RG | 1 |
| Liddy, EP | 1 |
| Klein, LR | 1 |
| Weiss, PH | 2 |
| Hurych, J | 2 |
| Mirejovská, E | 1 |
| Brokes, P | 1 |
| Weissová, J | 1 |
| Mikotová, J | 1 |
| Adam, M | 1 |
| Niinikoski, J | 1 |
| Morris, JJ | 1 |
| Geever, EF | 1 |
| Suzuki, F | 1 |
| Koyama, E | 1 |
| Klein, L | 1 |
| Manning, JM | 1 |
| Meister, A | 1 |
2 reviews available for hydroxyproline and Granuloma
| Article | Year |
|---|---|
Function of ascorbic acid in collagen metabolism.
Topics: Animals; Ascorbic Acid; Chick Embryo; Collagen; Glycine; Granuloma; Guinea Pigs; Hydroxyproline; Iro | 1975 |
Biological hydroxylations and ascorbic acid with special regard to collagen metabolism.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cells, Cultured; Collagen; Culture Techniques; Dopamine bet | 1972 |
116 other studies available for hydroxyproline and Granuloma
| Article | Year |
|---|---|
Hydroxyproline content and fibrogenesis in mouse liver and lungs during the early stages of BCG granulomatosis.
Topics: Animals; Cell Proliferation; Fibroblasts; Fibrosis; Granuloma; Granuloma, Respiratory Tract; Hydroxy | 2013 |
The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factors; Extracellular Matrix Proteins; Femal | 2014 |
Fibrogenesis in granulomas and lung interstitium in tuberculous inflammation in mice.
Topics: Animals; BCG Vaccine; Cell Proliferation; Disease Models, Animal; Fibroblasts; Granuloma; Hydroxypro | 2014 |
Study of fibrotic complications and hydroxyproline content in mouse liver at different stages of generalized BCG-induced granulomatosis.
Topics: Acute Disease; Animals; BCG Vaccine; Chronic Disease; Collagen; Fibroblasts; Granuloma; Hepatocytes; | 2014 |
Serum, liver, and lung levels of the major extracellular matrix components at the early stage of BCG-induced granulomatosis depending on the infection route.
Topics: Animals; BCG Vaccine; Glycosaminoglycans; Granuloma; Hydroxyproline; Liver; Lung; Male; Mice; Mice, | 2015 |
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap | 2011 |
The relation of ascorbic acid to the conversion of proline to hydroxyproline in the synthesis of collagen in the carrageenan granuloma.
Topics: Ascorbic Acid; Carrageenan; Collagen; Encephalomyelitis; Granuloma; Hydroxyproline; Neoplasms; Proli | 1959 |
Morphological and chemical studies of collagen formation. II. Metabolic activity of collagen associated with subcellular fractions of guinea pig granulomata.
Topics: Animals; Chromatography, Ion Exchange; Collagen; Granuloma; Guinea Pigs; Hydroxyproline; Proline; Su | 1961 |
Biological significance of peptide containing hydroxyproline during the development of carrageenin granuloma.
Topics: Carrageenan; Granuloma; Humans; Hydroxyproline; Peptides | 1960 |
Influence of methylthiouracil on biochemical changes in experimental granuloma.
Topics: DNA; Granuloma; Hexosamines; Hydroxyproline; Methylthiouracil; Nitrogen | 1962 |
[EFFECT OF METHYLTHIOURACIL ON THE FORMATION OF CONNECTIVE TISSUE IN EXPERIMENTAL GRANULOMA].
Topics: Connective Tissue; DNA; Granuloma; Hexosamines; Hydroxyproline; Methylthiouracil; Nitrogen; Rats; Re | 1963 |
[BIOCHEMICAL CHANGES DURING THE COURSE OF THE DEVELOPMENT OF CARRAGEENIN GRANULOMA WITH DEFICIENCY OF, OR INCREASED SATURATION WITH ASCORBIC ACID].
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carrageenan; Collagen; DNA; Eukaryota; Granulation | 1963 |
EFFECT OF LATHYRISM ON NUCLEIC ACIDS AND SUBCELLULAR PARTICLES OF THE EXPERIMENTAL GRANULATION TISSUE.
Topics: Capillaries; Cyanides; DNA; Granulation Tissue; Granuloma; Hydroxyproline; Lathyrism; Mitochondria; | 1963 |
[EFFECT OF PHENYLBUTAZONE ON BIOCHEMICAL CHANGES IN EXPERIMENTAL GRANULOMA].
Topics: DNA; Exudates and Transudates; Granuloma; Hexosamines; Hydroxyproline; Pharmacology; Phenylbutazone; | 1964 |
COLLAGEN SYNTHESIS AND C14-LABELED PROLINE UPTAKE AND CONVERSION TO HYDROXYPROLINE IN STEROID-TREATED GRANULOMAS.
Topics: Amino Acids; Collagen; Cortisone; Dexamethasone; Granuloma; Hydrocortisone; Hydroxyproline; Pharmaco | 1964 |
STUDIES ON THE CONNECTIVE TISSUE. 3. BIOSYNTHESIS OF COLLAGEN BY THE GRANULOMA TISSUE IN VITRO.
Topics: Amino Acids; Benzoates; Carbon Isotopes; Chloramphenicol; Collagen; Connective Tissue; Electrons; Ge | 1964 |
THE INFLUENCE OF HYDROCORTISONE AND SODIUM SALICYLATE ON THE BIOSYNTHESIS AND DEGRADATION OF COLLAGEN PROTEINS.
Topics: Collagen; Granuloma; Hydrocortisone; Hydroxyproline; Pharmacology; Proteins; Rats; Research; Sodium | 1965 |
EFFECT OF FORMALDEHYDE-INDUCED PERIARTHRITIS UPON THE COMPOSITION OF COTTON-PELLET GRANULOMA IN RATS.
Topics: Chemical Phenomena; Chemistry; DNA; Formaldehyde; Granuloma; Hydroxyproline; Periarthritis; Pharmaco | 1965 |
Changes of ultrafiltrable hydroxyproline in blood serum during development of carrageenin granuloma and during aging of rats and guinea-pigs.
Topics: Aging; Animals; Carrageenan; Granuloma; Guinea Pigs; Hydroxyproline; Plants; Proline; Rats; Serum | 1961 |
Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.
Topics: Animals; Granuloma; Hydroxyproline; Hypersensitivity, Delayed; Inflammation; Interferon-gamma; Inter | 2004 |
A novel nonsteroidal antifibrotic oligo decoy containing the TGF-beta element found in the COL1A1 gene which regulates murine schistosomiasis liver fibrosis.
Topics: Animals; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Consensus Sequence; DNA; Female; | 2005 |
The effect of 6-mercaptopurine on the inflammatory response stimulated by subcutaneous implantation of polyvinyl sponge.
Topics: Animals; Connective Tissue; Foreign Bodies; Granuloma; Granuloma, Giant Cell; Guinea Pigs; Hydroxypr | 1967 |
Reflection of collagen synthesis in experimental granulation tissue on plasma protein-bound hydroxyproline.
Topics: Animals; Collagen; Granulation Tissue; Granuloma; Hydroxyproline; In Vitro Techniques; Protein Bindi | 1967 |
Metabolic phases during the development of granulation tissue.
Topics: Animals; Back; Carbon Isotopes; Cellulose; Collagen; Glucose; Granulation Tissue; Granuloma; Hydroxy | 1967 |
Anti-inflammatory activity of 6-azauridine.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Body Weight; Carrageenan; DNA; Edema; Extremitie | 1967 |
Macrophage regulation of collagen deposition in granuloma tissue in vivo and the effect of prostaglandin E2.
Topics: Animals; Carrageenan; Collagen; Dinoprostone; Granuloma; Hydroxyproline; Macrophages; Male; Microbia | 1981 |
Colchicine and wound healing.
Topics: Animals; Colchicine; Collagen; Connective Tissue; Connective Tissue Diseases; Dose-Response Relation | 1980 |
Effect of 2-aminoethyl-L-cysteine on collagen accumulation in isolated hepatic granulomas.
Topics: Animals; Collagen; Cysteine; Dose-Response Relationship, Drug; Female; Granuloma; Hydroxylation; Hyd | 1983 |
Hepatic fibrosis in Schistosoma haematobium-infected mice.
Topics: Animals; Collagen; Female; Granuloma; Hydroxyproline; Liver; Liver Diseases; Mice; Schistosoma haema | 1983 |
Collagen metabolism and phenotype after prostaglandin E2 treatment of granuloma: direct and macrophage-modulated effects.
Topics: Animals; Carrageenan; Collagen; Dinoprostone; DNA; Granuloma; Hydroxyproline; Macrophages; Male; Phe | 1982 |
Experimental silicosis. I. Acute effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Lung; Particle Size; Proline; Proteins; Quartz; Rats; | 1982 |
The effect of cis-hydroxyproline on de novo synthesized collagen in subcutaneously implanted polyvinyl sponges in rats.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Prostheses and Implants; Rats; Stereoisomerism | 1982 |
The effect of chronic alcoholism on wound healing.
Topics: Alcoholism; Animals; Disease Models, Animal; Granuloma; Humans; Hydroxyproline; Male; Mice; Skin; Te | 1981 |
The artificial granuloma. III. Collagen synthesis during the cell-mediated granulomatous response as determined in explanted granulomas.
Topics: Animals; Antigens; Collagen; Female; Granuloma; Hydroxyproline; Immunity, Cellular; Inflammation; Lu | 1981 |
Antigen-induced alveolitis: cytokine production in a mouse model.
Topics: Alveolitis, Extrinsic Allergic; Animals; Antigens; Bronchoalveolar Lavage Fluid; Cytokines; Erythroc | 1995 |
Studies on rehmanniae radix. I. Effect of 50% ethanolic extract from steamed and dried rehmanniae radix on hemorheology in arthritic and thrombosic rats.
Topics: Acetates; Animals; Arthritis, Experimental; Blood Cell Count; Blood Viscosity; Capillary Permeabilit | 1994 |
Regression of hepatic lesions after treatment of Schistosoma mansoni or Schistosoma japonicum infection in mice: a comparative study.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Liver; Lung; Mice; Praziquantel; Schistosoma japonicum | 1993 |
The use of angiostatic steroids to inhibit cartilage destruction in an in vivo model of granuloma-mediated cartilage degradation.
Topics: Animals; Cartilage; Cortisone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therap | 1993 |
Oxaceprol, an atypical inhibitor of inflammation and joint damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Dinoprostone | 1996 |
Dexamethasone abrogates the fibrogenic effect of transforming growth factor-beta in rat granuloma and granulation tissue fibroblasts.
Topics: Animals; Collagen; Dexamethasone; Fibroblasts; Granulation Tissue; Granuloma; Hydroxyproline; Male; | 1997 |
Fibrous tissue and angiotensin II.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Collagen; Connective Tissue; Crot | 1997 |
[Effects of diacerhein on cytokine determinations in a model of cartilage degradation induced by granuloma in mice].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; D | 1997 |
Thalidomide reduces vascular density in granulation tissue of subcutaneously implanted polyvinyl alcohol sponges in guinea pigs.
Topics: Animals; Cricetinae; DNA; Foreign-Body Reaction; Granuloma; Hydroxyproline; Male; Neovascularization | 1998 |
Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Granuloma; Hydroxyproline; Lu | 1998 |
Effects of diacerhein on granuloma induced cartilage breakdown in the mouse.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; D | 1998 |
[The fibrogenic effect of artificial ceramic fibres in experimental rats].
Topics: Aluminum Silicates; Animals; Granuloma; Hydroxyproline; Intubation, Intratracheal; Lung; Lymph Nodes | 2000 |
Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni.
Topics: Animals; Collagen; Disease Models, Animal; Granuloma; Hydroxyproline; Immunohistochemistry; Leptin; | 2002 |
Vitamin A prevention of triamcinolone acetonide effects on granuloma growth: lack of effect on prolyl hydroxylase.
Topics: Animals; Collagen; DNA; Granuloma; Hydroxyproline; Male; Procollagen-Proline Dioxygenase; Proteins; | 1976 |
[Peptidyl prolyl hydroxylase activity in relation to the actual collagen biosynthesis in cotton pellet granuloma of guinea pig (author's transl)].
Topics: Animals; Collagen; Gossypium; Granuloma; Guinea Pigs; Hydroxyproline; Procollagen-Proline Dioxygenas | 1977 |
Arginine: an essential amino acid for injured rats.
Topics: Animals; Arginine; Body Weight; Collagen; Diet; Granuloma; Growth; Hydroxyproline; Male; Rats; Wound | 1978 |
[Action of carbon tetrachloride on the quality of hepatic collagen].
Topics: Aging; Animals; Carbon Tetrachloride Poisoning; Collagen; Female; Granuloma; Hydroxyproline; Liver; | 1975 |
Liver collagen synthesis in murine schistosomiasis.
Topics: Animals; Azetidinecarboxylic Acid; Collagen; Female; Granuloma; Hydroxyproline; Liver; Liver Disease | 1977 |
The effects of prostaglandin F2alpha on vascular permeability and collagen and non-collagen protein synthesis of preformed chronic carrageenin granuloma in rats.
Topics: Animals; Capillary Permeability; Carrageenan; Collagen; Granuloma; Hydroxyproline; In Vitro Techniqu | 1977 |
Effect of the administration of antirheumatic drugs on experimental granuloma in rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cellulose; Cytidine; Granuloma; Hexosamines; Hydroxyprol | 1975 |
Collagen profile in rat granulation tissue after cyclophosphamide treatment.
Topics: Animals; Collagen; Cyclophosphamide; Granulation Tissue; Granuloma; Hydroxyproline; Male; Organ Size | 1975 |
Urinary excretion of hydroxylysyl glycosides during acute inflammation in the rat.
Topics: Acute Disease; Animals; Galactosides; Glucosides; Granuloma; Hydroxylysine; Hydroxyproline; Rats | 1976 |
Mechanism of action of retinyl compounds on wound healing IV: effect of desmethylretinoic acid and its vinylogs on granuloma formation.
Topics: Animals; Chemical Phenomena; Chemistry; Gossypium; Granuloma; Hexosamines; Hydroxyproline; Rats; Tre | 1976 |
The effect of zinc deficiency on granuloma formation, liver fibrosis, and antibody responses in experimental schistosomiasis.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Collagen; Granuloma; Helminth Proteins; Hydroxypr | 1992 |
Effect of acute phase proteins, especially alpha 2-macroglobulin, on granuloma formation around Schistosoma mansoni eggs in the rat.
Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Collagen; Granuloma; Host-Parasite Interactions | 1991 |
Instability of the myofibroblast phenotype in culture.
Topics: Animals; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Techniques; Fibroblasts; Fluoresce | 1990 |
[Mechanism of action of pronase on chronic proliferative inflammation including granuloma angiogenesis in mice].
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Granuloma; Hydrocortisone; Hydroxyproline; Indom | 1986 |
The course of healing of the inflammatory granuloma in rats after the application of tetrachlormethane and 6-azauridine.
Topics: Animals; Azauridine; Carbon Tetrachloride; Glycoproteins; Granuloma; Hydroxyproline; Inflammation; L | 1985 |
Insulin-induced granuloma tissue formation and angiogenesis in alloxan-treated diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Freund's Adjuvant; Granuloma; Hydroxyproline; Insulin; Mal | 1987 |
Inhibition of wound repair by thymic hormones.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Thymus Ho | 1989 |
Collagen prolyl hydroxylase inhibitor and reduced collagen formation in cotton pellet-induced granuloma and skin wound healing in rats.
Topics: Animals; Anthraquinones; Collagen; Female; Granuloma; Hydroxyproline; Procollagen-Proline Dioxygenas | 1985 |
Serum aminoterminal type III procollagen peptide. Relation to biosynthesis of collagen type III in experimentally induced granulation tissue in rats.
Topics: Animals; Granuloma; Hydroxyproline; Immunoenzyme Techniques; Peptide Fragments; Procollagen; Rats; R | 1988 |
Formation of granulomas in liver of silica-treated rats.
Topics: Animals; Aspartic Acid Endopeptidases; beta-Galactosidase; DNA; Endopeptidases; Female; Granuloma; H | 1986 |
A biochemical study of the carrageenan-induced granuloma in the rat lung.
Topics: Acetylglucosaminidase; Animals; Carrageenan; Cathepsin B; Cathepsins; Collagen; Granuloma; Hydroxypr | 1985 |
Extracellular matrix in hepatic granulomas of mice infected with Schistosoma mansoni. Qualitative and quantitative analysis.
Topics: Animals; Extracellular Matrix; Fluorescent Antibody Technique; Glycosaminoglycans; Granuloma; Hydrox | 1985 |
Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Isoquinolines; Liver; Liver Diseases; Male; Mice; Orga | 1985 |
Fibroblast stimulating activity of extracts of hepatic granulomata of Schistosoma mansoni-infected rodents with marked or slight hepatic fibrosis.
Topics: Animals; Cricetinae; Fibroblasts; Granuloma; Hydroxyproline; Liver; Liver Diseases, Parasitic; Liver | 1985 |
[Investigations on the effect of thyroid function on collagen metabolism].
Topics: Animals; Collagen; Glycosaminoglycans; Gossypium; Granuloma; Hydroxyproline; Hyperthyroidism; Neopla | 1966 |
Vitamin C deficiency and connective tissue. IV. Determinations of mucopolysaccharides and collagen in carrageenan-granulomas.
Topics: Animals; Ascorbic Acid Deficiency; Azoles; Carrageenan; Chemistry Techniques, Analytical; Collagen; | 1966 |
The effect of polyvinylpyridine-N-oxide on the sulphate metabolism of carrageenin granuloma.
Topics: Acid Phosphatase; Animals; Carrageenan; Chondroitin; Glycosaminoglycans; Granuloma; Hydroxyproline; | 1968 |
Relationship between the dose of ascorbic acid and its structural analogs and proline hydroxylation in various biological systems.
Topics: Animals; Ascorbic Acid; Carbon Radioisotopes; Carrageenan; Chick Embryo; Chromatography, Paper; Coll | 1974 |
Further evidence for the accumulation of a hydroxyproline-deficient, collagenase-degradable protein during collagen biosynthesis in vitro.
Topics: Animals; Chick Embryo; Collagen; Granuloma; Guinea Pigs; Hydroxyproline; In Vitro Techniques; Microb | 1966 |
Soluble collagen proline hydroxylase and its substrates in several animal tissues.
Topics: Animals; Chick Embryo; Fetus; Granuloma; Guinea Pigs; Hydroxyproline; In Vitro Techniques; Liver; Mi | 1966 |
Conflicting hypotheses on experimental silicotic fibrogenesis: new experimental data.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Collagen; Dust; Granuloma; Guinea Pigs; Hydroxyproline; Liv | 1967 |
Hydroxylation of proline residues in collagen nascent chains.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatog | 1970 |
Purification on a structural glycoprotein from collagenase-digested experimental granuloma.
Topics: Amino Acids; Animals; Cellulose; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatogra | 1971 |
Collagenolytic enzymes and acid-proteinase activity in granuloma tissue.
Topics: Animals; Cathepsins; Collagen; Granuloma; Hydrogen-Ion Concentration; Hydroxyproline; Microbial Coll | 1974 |
Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase and hydroxylation of collagen in various tissues of rats.
Topics: Animals; Animals, Newborn; Body Weight; Calcium; Carrageenan; Collagen; Deferoxamine; Estradiol; Fem | 1974 |
Effect of thiamine deficiency on collagen metabolism.
Topics: Animals; Carbon Radioisotopes; Collagen; DNA; Glycine; Gossypium; Granuloma; Hydrogen-Ion Concentrat | 1974 |
Acid hydrolase activity in the resorbing carrageenan granuloma.
Topics: Acid Phosphatase; Animals; Carrageenan; Cathepsins; Collagen; Galactosidases; Glucuronidase; Granulo | 1974 |
[Biochemical studies on action mechnism of a new anti-inflammatory agent, naproxen (1). Effects of naproxen on changes in connective tissue components due to inflammation].
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Connective Tissue; Dimethylamines; Female; Gran | 1974 |
Radiation injury of connective tissue. A biochemical investigation with experimental granuloma.
Topics: Animals; Cell Division; Collagen; Connective Tissue; Connective Tissue Cells; Cytidine; DNA; Dose-Re | 1973 |
Effects of serotonin, indomethacin and other antirheumatic drugs on the synthesis of collagen and other proteins in granulation tissue slices.
Topics: Animals; Bradykinin; Collagen; Epinephrine; Granulation Tissue; Granuloma; Histamine; Hydroxyproline | 1972 |
Modifications of collagen and non fibrillar-proteins and cathepsin activity in the carrageenin granuloma.
Topics: Animals; Carrageenan; Cathepsins; Collagen; Exudates and Transudates; Female; Granulation Tissue; Gr | 1972 |
[Modifications of protein metabolism induced by hydrocortisone in carrageenin granulomas].
Topics: Animals; Carrageenan; Cathepsins; Collagen; Exudates and Transudates; Female; Granuloma; Hydrocortis | 1972 |
Evidence for the inhibition of protocollagen biosynthesis by an anti-inflammatory steroid in rat carrageenin granuloma.
Topics: Animals; Betamethasone; Carrageenan; Collagen; Granuloma; Hydroxyproline; Kinetics; Male; Phosphates | 1972 |
Mechanism of action of retinyl compounds on wound healing. 3. Effect of retinoic acid homologs on granuloma formation.
Topics: Animals; Gossypium; Granuloma; Hexosamines; Hydroxyproline; Magnetic Resonance Spectroscopy; Rabbits | 1973 |
Amino acid metabolism of experimental granulation tissue in vitro.
Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cellulose; Chromatography, Ion Exchange | 1973 |
A reassessment of the collagen reutilization theory by an isotope ratio method.
Topics: Animals; Carbon Radioisotopes; Collagen; Female; Glycine; Granuloma; Hydroxyproline; Isotope Labelin | 1973 |
A study of collagen reutilization using an 18O2 labeling technique.
Topics: Animals; Chromatography, Gas; Chromatography, Paper; Collagen; Granuloma; Hydroxyproline; Isotope La | 1974 |
Effect of cis-hydroxyproline on collagen and other proteins in skin wounds, granuloma tissue, and liver of mice and rats.
Topics: Animals; Biomechanical Phenomena; Body Weight; Collagen; Granuloma; Hydroxyproline; Lethal Dose 50; | 1974 |
[Action of thyroxine on catheptic activity of granuloma induced by carrageenan].
Topics: Animals; Carrageenan; Cathepsins; Collagen; Granuloma; Hydroxyproline; Proline; Rats; Thyroxine | 1970 |
Connective tissue reactions to lambda-carrageenan in the rat. Lambda-carrageenan-collagen interaction.
Topics: Animals; Carrageenan; Chemical Phenomena; Chemical Precipitation; Chemistry; Collagen; Connective Ti | 1972 |
Action of betamethasone disodium phosphate on the metabolism of collagen and noncollagen protein in rat carrageenin granuloma.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Biodegradation, Environmental; Body Weight; Carrag | 1972 |
Growth hormone inhibition of proline hydroxylation in vitro.
Topics: Animals; Bone and Bones; Carbon Isotopes; Carrageenan; Collagen; Depression, Chemical; Female; Granu | 1971 |
Collagen reutilization in normal and hypersomatotrophic rats.
Topics: Animals; Collagen; Female; Granulation Tissue; Granuloma; Growth Hormone; Hydroxyproline; Hyperpitui | 1971 |
Collagen metabolism in bone and carrageenin granuloma by sulfate-deprived and sulfate-supplemented rats.
Topics: Animals; Bone and Bones; Carbon Isotopes; Carrageenan; Collagen; Diet; Granuloma; Hydroxyproline; Pr | 1971 |
Effect of estradiol-17 on collagen biosynthesis, degradation and re-utilization in vivo.
Topics: Animals; Bone and Bones; Carbon Isotopes; Carrageenan; Collagen; Estradiol; Female; Granuloma; Guine | 1971 |
Induced connective tissue metabolism in vivo: reutilization of pre-existing collagen.
Topics: Animals; Ascorbic Acid Deficiency; Chromatography; Collagen; Connective Tissue; Granuloma; Guinea Pi | 1966 |
The effect of locally injected anti-inflammatory drugs on the synthesis of collagen and non-collagen protein of carrageenin granuloma in rats.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Body Weight; Carrageenan; Collagen; Granuloma; Hyd | 1969 |
Inhibition of the effect of D-penicillamine on collagen solubility in skin by 17-beta-estradiol cypionate; and the effect of D-penicillamine and 17-beta-estradiol on the abnormalities in rat bone produced by a low calcium diet.
Topics: Animals; Aorta; Bone and Bones; Calcium, Dietary; Carbon Isotopes; Carrageenan; Collagen; Deficiency | 1970 |
Mechanism of action of retinyl compounds on wound healing. II. Effect of active retinyl derivatives on granuloma formation.
Topics: Animals; Gossypium; Granulation Tissue; Granuloma; Hexosamines; Hydroxyproline; Male; Polyvinyls; Pr | 1970 |
Effect of long-term hypoxia on protein synthesis in granuloma and in some organs in rats.
Topics: Animals; Carbon Isotopes; Collagen; Female; Granuloma; Hydroxyproline; Hypoxia; Intestine, Small; Li | 1970 |
Distribution of hydroxyproline and hydroxylysine deficient collagen in individual collagen fractions in the granuloma tissue.
Topics: Amino Acid Sequence; Animals; Carbon Isotopes; Chick Embryo; Chromatography, Paper; Collagen; Granul | 1968 |
Effect of estrogen on in vivo and in vitro collagen biosynthesis and maturation in old and young female guinea pigs.
Topics: Age Factors; Animals; Aorta; Bone and Bones; Carbon Isotopes; Carrageenan; Collagen; Connective Tiss | 1968 |
The metabolism of blood serum glycoproteins in rats with experimental granuloma after glucosamine-1-14C injection.
Topics: Animals; Bile Acids and Salts; Blood Proteins; Carbon Isotopes; Glucosamine; Glycoproteins; Granulom | 1968 |
Effect of hyperbaric oxygenation on wound healing and experimental granuloma.
Topics: Animals; Cellulose; Chemical Phenomena; Chemistry; Granuloma; Hemoglobins; Hydroxyproline; Hyperbari | 1968 |
Effect of penicillamine upon healing wounds.
Topics: Alcohols; Animals; Collagen; Collagen Diseases; Diet; Formaldehyde; Granuloma; Hydroxyproline; Male; | 1969 |
Hydroxylation of proline in collagen model peptide.
Topics: Animals; Collagen; Granuloma; Guinea Pigs; Hydroxyproline; Models, Chemical; Peptides; Proline | 1969 |
Reutilization of mature collagen in vivo.
Topics: Animals; Bone and Bones; Carrageenan; Chromatography, Ion Exchange; Collagen; Connective Tissue; Gra | 1965 |
Conversion of proline to collagen hydroxyproline.
Topics: Animals; Borates; Carrageenan; Chlortetracycline; Collagen; Granuloma; Guinea Pigs; Hydroxyproline; | 1966 |
Uptake of S35-methionine and S35-chondroitin sulphate by the carrageenin granuloma in rats of different ages.
Topics: Animals; Blood Flow Velocity; Carrageenan; Chondroitin; Granulation Tissue; Granuloma; Hydroxyprolin | 1966 |