Page last updated: 2024-11-06

hydroxyproline and Fibrous Dysplasia of Bone

hydroxyproline has been researched along with Fibrous Dysplasia of Bone in 16 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Fibrous Dysplasia of Bone: A disease of bone marked by thinning of the cortex by fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC).

Research Excerpts

ExcerptRelevanceReference
"A 12-year-old Japanese girl with polyostotic fibrous dysplasia and endocrine concomitants, was treated with elcatonin, a synthetic eel calcitonin analogue, 10 MRC unit/twice a week given by intramuscular injection."1.27Suppressive effect of elcatonin, an eel calcitonin analogue, on excessive urinary hydroxyproline excretion in polyostotic fibrous dysplasia (McCune-Albright's syndrome). ( Harada, Y; Ishikawa, J; Ishitobi, K; Kishimoto, H; Maeyama, I; Morio, Y; Yamamoto, K, 1983)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GOIDANICH, IF1
LENZI, L1
SILVA, E1
Yamamoto, K1
Maeyama, I1
Kishimoto, H1
Morio, Y1
Harada, Y1
Ishitobi, K1
Ishikawa, J1
Liens, D1
Delmas, PD1
Meunier, PJ1
Enderle, A1
von Gumppenberg, S1
Arata, RO1
Campos, C1
Mautalen, CA1
Long, A1
Loughlin, T1
Towers, RP1
McKenna, TJ1
Morii, H2
Tanae, A1
Ibayashi, H1
Nakao, K1
Beck, O1
Schramm, G1
Kyselka, R1
Krane, SM1
Muñoz, AJ1
Harris, ED1
Nichols, G1
Flanagan, B1
van der Sluys Veer, J1
Johnson, JW1
Hampers, CL1
Merrill, JP1
Bell, NH1
Avery, S1
Johnston, CC1
Niejadlik, DC1
Bishop, MC1
Smith, R1
Fischer, JA1
Bollinger, A1
Lichtlen, P1
Wellauer, J1
De Vita, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Trial of Alendronate in the Treatment of Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome[NCT00001728]Phase 240 participants (Actual)Interventional1998-08-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyproline and Fibrous Dysplasia of Bone

ArticleYear
[Problems concerning clinical application of calcitonin].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:3

    Topics: Adult; Aged; Alkaline Phosphatase; Calcitonin; Calcium; Child, Preschool; Female; Fibrous Dysplasia

1972

Trials

1 trial available for hydroxyproline and Fibrous Dysplasia of Bone

ArticleYear
Effects of calcitonin in Paget's disease and polyostotic fibrous dysplasia.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:3

    Topics: Adolescent; Aged; Alkaline Phosphatase; Calcitonin; Calcium; Clinical Trials as Topic; Collagen; Cre

1970

Other Studies

14 other studies available for hydroxyproline and Fibrous Dysplasia of Bone

ArticleYear
URINARY HYDROXYPROLINE EXCRETION IN NORMAL SUBJECTS AND IN PATIENTS AFFECTED WITH PRIMARY DISEASES OF BONE.
    Clinica chimica acta; international journal of clinical chemistry, 1965, Volume: 11

    Topics: Adolescent; Amino Acids; Body Fluids; Bone Diseases; Child; Fibrous Dysplasia of Bone; Fluids and Se

1965
Suppressive effect of elcatonin, an eel calcitonin analogue, on excessive urinary hydroxyproline excretion in polyostotic fibrous dysplasia (McCune-Albright's syndrome).
    Endocrinologia japonica, 1983, Volume: 30, Issue:5

    Topics: Alkaline Phosphatase; Calcitonin; Calcium; Child; Female; Fibrous Dysplasia of Bone; Fibrous Dysplas

1983
Long-term effects of intravenous pamidronate in fibrous dysplasia of bone.
    Lancet (London, England), 1994, Apr-16, Volume: 343, Issue:8903

    Topics: Adolescent; Adult; Alkaline Phosphatase; Diphosphonates; Female; Fibrous Dysplasia of Bone; Follow-U

1994
[Osteitis deformans (Paget)--or a tarda-type of a hereditary hyperphosphatasia (author's transl)].
    Archives of orthopaedic and traumatic surgery. Archiv fur orthopadische und Unfall-Chirurgie, 1979, Jul-31, Volume: 94, Issue:2

    Topics: Adult; Alkaline Phosphatase; Bone Transplantation; Calcitonin; Deafness; Diagnosis, Differential; Di

1979
Effect of parathyroid hormone on bone resorption in uremic patients.
    Medicina, 1976, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Bone Resorption; Female; Fibrous Dysplasia of Bone; Humans;

1976
Polyostotic fibrous dysplasia with contrasting responses to calcitonin and mithramycin: aetiological and therapeutic implications.
    Irish journal of medical science, 1988, Volume: 157, Issue:7

    Topics: Adolescent; Alkaline Phosphatase; Calcitonin; Calcium; Fibrous Dysplasia of Bone; Fibrous Dysplasia,

1988
Effects of calcitonin in metastatic bone carcinoma, osteoporosis, polyostotic fibrous dysplasia and hypercalcemia.
    Endocrinologia japonica, 1971, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcitonin; Calcium; Child, Presc

1971
[Does the determination of acid mucopolysaccharides and hydroxyproline contribute to the differential diagnosis of fibrous dysplasia (Jaffé-Lichtenstein) and osteogenesis imperfecta congenita?].
    Beitrage zur Orthopadie und Traumatologie, 1972, Volume: 19, Issue:12

    Topics: Diagnosis, Differential; Fibrous Dysplasia of Bone; Fractures, Spontaneous; Glycosaminoglycans; Huma

1972
Urinary polypeptides related to collagen synthesis.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:4

    Topics: Adenoma; Adolescent; Adult; Aged; Amino Acids; Bone Diseases; Carbon Isotopes; Chromatography, Gel;

1970
Metabolic studies of bone in uremia before and after treatment.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4

    Topics: Adult; Azathioprine; Bone and Bones; Bone Resorption; Carbon Isotopes; Chronic Kidney Disease-Minera

1972
Hydroxyproline.
    Postgraduate medicine, 1972, Volume: 51, Issue:5

    Topics: Bone and Bones; Bone Diseases; Bone Neoplasms; Burns; Collagen; Collagen Diseases; Fibrous Dysplasia

1972
Non-protein-bound hydroxyproline in plasma in renal bone disease.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:2

    Topics: Alkaline Phosphatase; Bone and Bones; Bone Diseases; Bone Resorption; Creatinine; Fibrous Dysplasia

1971
Fibrous dysplasia of the bone and high cardiac output.
    The American journal of medicine, 1970, Volume: 49, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Biopsy; Blood Circulation; Bone and Bones; Bone Regeneration; Bon

1970
[The urinary excretion of hydroxyproline in patients with fibrous dysplasia].
    Archivio italiano di chirurgia, 1965, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Aged; Fibrous Dysplasia of Bone; Humans; Hydroxyproline; In Vitro Techniques; Mid

1965