Page last updated: 2024-11-06

hydroxyproline and Experimental Radiation Injuries

hydroxyproline has been researched along with Experimental Radiation Injuries in 44 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes."5.30The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998)
" Radiation induced fibrosis was evaluated by determining the ratio of hydroxyproline concentration of irradiated and non-irradiated lung in the same animal."3.68The hydroxyproline content in the lung tissue of young pigs after fractionated irradiation with photons or neutrons. ( Herrmann, T; Knorr, A; Voigtmann, L, 1991)
"The effect of MSC transplantation on lung injury was then evaluated 180 days after transplantation."1.48Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury. ( Dai, J; Dai, X; Fang, J; Feng, C; Hao, J; Hao, Y; Li, J; Li, R; Liu, J; Lu, B; Ma, R; Qiao, Z; Ran, Y; Xiong, W; Zhang, J; Zhou, Q, 2018)
" This study investigated whether irradiation of small lung volumes with high fibrogenic doses affects the dose-response relationship for development of fibrosis in distant parts of the ipsilateral lung of mini-pigs."1.31Lack of effect of small high-dose volumes on the dose-response relationship for the development of fibrosis in distant parts of the ipsilateral lung in mini-pigs. ( Appold, S; Baumann, M; Geyer, P; Herrmann, T; Knorr, A; Voigtmann, L, 2000)
"The hydroxyproline (Hyp) content was measured in the pulmonary tissue after digestion with HCl."1.30Kinetic alterations of angiotensin-II and nitric oxide in radiation pulmonary fibrosis. ( Cui, X; Shi, Z; Song, L; Wang, D; Yang, H, 1998)
"Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes."1.30The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199028 (63.64)18.7374
1990's8 (18.18)18.2507
2000's2 (4.55)29.6817
2010's5 (11.36)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Chung, EJ1
Kwon, S1
Reedy, JL1
White, AO1
Song, JS1
Hwang, I1
Chung, JY1
Ylaya, K1
Hewitt, SM1
Citrin, DE1
Hao, Y1
Ran, Y1
Lu, B1
Li, J1
Zhang, J1
Feng, C1
Fang, J1
Ma, R1
Qiao, Z1
Dai, X1
Xiong, W1
Liu, J1
Zhou, Q1
Hao, J1
Li, R1
Dai, J1
Ogata, T1
Yamazaki, H1
Teshima, T1
Kihara, A1
Suzumoto, Y1
Inoue, T1
Nishimoto, N1
Matsuura, N1
Yang, X1
Walton, W1
Cook, DN1
Hua, X1
Tilley, S1
Haskell, CA1
Horuk, R1
Blackstock, AW1
Kirby, SL1
Du, SS1
Qiang, M1
Zeng, ZC1
Zhou, J1
Tan, YS1
Zhang, ZY1
Zeng, HY1
Liu, ZS1
Zhang, H1
Han, G1
Liu, H1
Chen, J1
Ji, X1
Zhou, F1
Zhou, Y1
Xie, C1
DOTY, SB1
YATES, CW1
LOTZ, WE1
KISECLESKI, W1
TALMAGE, RV1
Johnson, LB1
Adawi, D1
Agren, MS1
Jorgensen, LN1
Wittgren, L1
Mattsson, S1
Blomquist, P1
Gottrup, F1
Jeppsson, B1
Down, JD1
Laurent, GJ1
McAnulty, RJ1
Steel, GG1
Hakkinen, PJ1
Whiteley, JW1
Witschi, HR1
Ward, WF1
Shih-Hoellwarth, A1
Tuttle, RD1
Adamson, IY1
Bowden, DH1
Reeves, WC1
Cunningham, D1
Schwiter, EJ1
Abt, A1
Skarlatos, S1
Wood, MA1
Whitesell, L1
Geraci, JP2
Jackson, KL1
Thrower, PD1
Mariano, MS2
Haschek, WM1
Meyer, KR1
Ullrich, RL1
Witschi, HP1
Norrdin, RW1
Miller, CW1
LoPresti, CA1
Taylor, AN1
Arnold, JS1
Jahnson, S1
Graf, W1
Rikner, G1
Gerdin, B1
Song, L2
Wang, D2
Cui, X2
Shi, Z1
Yang, H1
Hu, W1
Seifert, WF1
Biert, J1
Wobbes, T1
Verhofstad, AA1
Hoogenhout, J1
Hendriks, T1
Baumann, M1
Appold, S1
Geyer, P1
Knorr, A3
Voigtmann, L3
Herrmann, T3
Thyagarajan, P1
Vakil, UK1
Sreenivasan, A1
Forsberg, JO1
Jiborn, H1
Jung, B1
Ohuchi, K1
Chang, LF1
Tabachnick, J1
Dubrawsky, C1
Dubravsky, NB1
Withers, HR1
Gross, NJ1
Vladescu, C1
Gheorghe, N1
Ganea, E1
Petrescu, L1
Dancewicz, AM1
Mazanowska, A1
Gerber, GB1
Law, MP2
Hornsey, S1
Field, SB1
Breuer, R1
Tochner, Z1
Conner, MW1
Nimrod, A1
Gorecki, M1
Or, R1
Slavin, S1
van Rongen, E1
Madhuizen, HT1
Tan, CH1
Durham, SK1
Gijbels, MJ1
Travis, EL1
Meistrich, ML2
Finch-Neimeyer, MV1
Watkins, TL1
Kiss, I1
Murray, JC1
Parkins, CS1
Ito, H1
Barkley, HT1
Thames, HD1
Milas, L1
Johannsen, U1
Range, U1
Bublitz, G1
Nesterova, VI1
Davydova, SA1
Poluboiarinova, ZI1
Vodiakova, LM1
Rantanen, J1
Stajic, J1
Jovanovic, M1
Pickrell, JA1
Shafer, J1
Ladner, HA1
Diethelm, L1
Deyhle, P1

Other Studies

44 other studies available for hydroxyproline and Experimental Radiation Injuries

ArticleYear
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis.
    International journal of radiation oncology, biology, physics, 2021, 06-01, Volume: 110, Issue:2

    Topics: Alveolar Epithelial Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cell Polarity; Cellular Senescen

2021
Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury.
    International journal of radiation oncology, biology, physics, 2018, 10-01, Volume: 102, Issue:2

    Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Flow C

2018
Early administration of IL-6RA does not prevent radiation-induced lung injury in mice.
    Radiation oncology (London, England), 2010, Apr-07, Volume: 5

    Topics: Animals; Antibodies, Monoclonal; Body Weight; Female; Gamma Rays; Hydroxyproline; Interleukin-6; Mic

2010
The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:1

    Topics: Animals; Chemokine CCL3; Gamma Rays; Hydroxyproline; Lung; Mice; Mice, Knockout; Phenylurea Compound

2011
Radiation-induced liver fibrosis is mitigated by gene therapy inhibiting transforming growth factor-β signaling in the rat.
    International journal of radiation oncology, biology, physics, 2010, Dec-01, Volume: 78, Issue:5

    Topics: Adenoviridae; Animals; Genetic Therapy; Genetic Vectors; Hepatic Stellate Cells; Hyaluronic Acid; Hy

2010
The development of classically and alternatively activated macrophages has different effects on the varied stages of radiation-induced pulmonary injury in mice.
    Journal of radiation research, 2011, Volume: 52, Issue:6

    Topics: Animals; Arginase; Female; Gene Expression; Hydroxyproline; Macrophage Activation; Macrophages; Mice

2011
EFFECT OF SHORT TERM ALPHA IRRADIATION ON PARATHYROID ACTIVITY AND OSTEOCLAST NUMBERS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Alpha Particles; Endocrinology; Hydroxyproline; Osteoclasts; Osteogenesis; Parathyroid Glands; Parat

1965
Combination of pre-operative radiotherapy and surgery suppresses local accumulation of collagen and TGF-beta1 in rats.
    The Journal of surgical research, 2006, Jun-15, Volume: 133, Issue:2

    Topics: Animals; Collagen; Combined Modality Therapy; Disease Models, Animal; Hydroxyproline; Laparotomy; Ma

2006
Oxygen-dependent protection of radiation lung damage in mice by WR 2721.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1984, Volume: 46, Issue:5

    Topics: Amifostine; Animals; Dose-Response Relationship, Radiation; Hair; Hydroxyproline; Lung; Male; Mice;

1984
Hyperoxia, but not thoracic X-irradiation, potentiates bleomycin- and cyclophosphamide-induced lung damage in mice.
    The American review of respiratory disease, 1982, Volume: 126, Issue:2

    Topics: Animals; Bleomycin; Collagen; Cyclophosphamide; DNA; Hydroxyproline; Male; Mice; Mice, Inbred BALB C

1982
Collagen accumulation in irradiated rat lung: modification by D-penicillamine.
    Radiology, 1983, Volume: 146, Issue:2

    Topics: Animals; Cobalt Radioisotopes; Collagen; Gamma Rays; Hydroxyproline; Lung; Male; Penicillamine; Pulm

1983
Endothelial injury and repair in radiation-induced pulmonary fibrosis.
    The American journal of pathology, 1983, Volume: 112, Issue:2

    Topics: Animals; Cell Division; Connective Tissue; DNA; Endothelium; Hydroxyproline; Lung; Male; Mice; Pulmo

1983
Myocardial hydroxyproline reduced by early administration of methylprednisolone or ibuprofen to rabbits with radiation-induced heart disease.
    Circulation, 1982, Volume: 65, Issue:5

    Topics: Animals; Heart Diseases; Hydroxyproline; Ibuprofen; Male; Methylprednisolone; Myocardium; Pericardia

1982
Relative biological effectiveness of cyclotron fast neutrons for late hepatic injury in rats.
    Radiation research, 1980, Volume: 82, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Fast Neutrons; Female; Gamma Rays; Hydroxyproline

1980
Potentiation of chemically induced lung fibrosis by thorax irradiation.
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:4

    Topics: Animals; Butylated Hydroxytoluene; Cell Division; Hydroxyproline; Lung; Male; Mice; Pulmonary Fibros

1980
Observations on calcium metabolism, 47Ca absorption, and duodenal calcium-binding activity in chronic renal failure: studies in Beagles with radiation-induced nephropathy.
    American journal of veterinary research, 1980, Volume: 41, Issue:4

    Topics: Animals; Blood Urea Nitrogen; Calcium; Dog Diseases; Dogs; Duodenum; Hydroxyproline; Intestinal Abso

1980
Anastomotic breaking strength and healing of anastomoses in rat intestine with and without chronic radiation damage.
    The European journal of surgery = Acta chirurgica, 1995, Volume: 161, Issue:6

    Topics: Anastomosis, Surgical; Animals; Hydroxyproline; Ileum; Male; Radiation Injuries, Experimental; Rats;

1995
Radiation hepatology of the rat: association of the production of prostacyclin with radiation-induced hepatic fibrosis.
    Radiation research, 1996, Volume: 145, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspartate Aminotransferases; Cesium Radioisotopes; Dose-Respo

1996
Kinetic alterations of angiotensin-II and nitric oxide in radiation pulmonary fibrosis.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1998, Volume: 17, Issue:2

    Topics: Angiotensin II; Animals; Azo Compounds; Hydroxyproline; Immunohistochemistry; In Situ Hybridization;

1998
The protective action of taurine and L-arginine in radiation pulmonary fibrosis.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1998, Volume: 17, Issue:2

    Topics: Animals; Arginine; Azo Compounds; Collagen; Hydroxyproline; Image Processing, Computer-Assisted; In

1998
Late effects of intraoperative radiation therapy in anastomotic rat colon.
    International journal of radiation oncology, biology, physics, 1998, Oct-01, Volume: 42, Issue:3

    Topics: Anastomosis, Surgical; Animals; Biomarkers; Colon; Hydroxyproline; Intraoperative Period; Male; Post

1998
Lack of effect of small high-dose volumes on the dose-response relationship for the development of fibrosis in distant parts of the ipsilateral lung in mini-pigs.
    International journal of radiation biology, 2000, Volume: 76, Issue:4

    Topics: Animals; Dose-Response Relationship, Radiation; Female; Hydroxyproline; Lung; Male; Pulmonary Fibros

2000
Effects of whole-body x-irradiation of some aspects of collagen metabolism in the rat.
    Radiation research, 1976, Volume: 66, Issue:3

    Topics: Animals; Collagen; Hydroxyproline; Liver; Male; Muscles; Procollagen-Proline Dioxygenase; Proline; R

1976
Protective effect of hypoxia against radiation induced fibrosis in the rat gut.
    Acta radiologica: oncology, radiation, physics, biology, 1979, Volume: 18, Issue:1

    Topics: Animals; Hydroxyproline; Hypoxia; Ileum; Intestinal Mucosa; Male; Microspheres; Radiation Dosage; Ra

1979
Radiation fibrosis of guinea pig skin after beta irradiation and an attempt at its suppression with proline analogs.
    Radiation research, 1979, Volume: 79, Issue:2

    Topics: Animals; Azetidinecarboxylic Acid; Collagen; Electrons; Guinea Pigs; Hydroxyproline; Male; Proline;

1979
The effect of colchicine on the accumulation of hydroxyproline and on lung compliance after irradiation.
    Radiation research, 1978, Volume: 73, Issue:1

    Topics: Animals; Colchicine; Collagen; Dose-Response Relationship, Drug; Hydroxyproline; Lung Compliance; Ma

1978
Experimental radiation pneumonitis: changes in physiology of the alveolar surface.
    The Journal of laboratory and clinical medicine, 1978, Volume: 92, Issue:6

    Topics: Animals; Female; Hydroxyproline; Lung; Lung Compliance; Macrophages; Mice; Phospholipids; Pleural Ef

1978
[Research on hepatic and overall collagen metabolism in irradiated rats (author's transl)].
    Pathologie-biologie, 1976, Volume: 24, Issue:10

    Topics: Adrenalectomy; Animals; Collagen; Dose-Response Relationship, Radiation; Hydroxyproline; Liver; Male

1976
Late biochemical changes in the rat lung after hemithoracic irradiation.
    Radiation research, 1976, Volume: 67, Issue:3

    Topics: Acid Phosphatase; Animals; Cathepsins; DNA; Fibrinolysis; Glucuronidase; Histamine; Hydroxyproline;

1976
Collagen content of lungs of mice after x-ray irradiation.
    Radiation research, 1976, Volume: 65, Issue:1

    Topics: Animals; Collagen; Dose-Response Relationship, Radiation; Female; Hydroxyproline; Lung; Mice; Radiat

1976
Superoxide dismutase inhibits radiation-induced lung injury in hamsters.
    Lung, 1992, Volume: 170, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Hydroxyproline; Lung; Male; Mesocricetus; Radiati

1992
The hydroxyproline content in the lung tissue of young pigs after fractionated irradiation with photons or neutrons.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1991, Volume: 167, Issue:11

    Topics: Animals; Fibrosis; Hydroxyproline; Lung; Neutrons; Radiation; Radiation Dosage; Radiation Injuries,

1991
Early and late effects of fractionated irradiation and the kinetics of repair in rat lung.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1990, Volume: 17, Issue:4

    Topics: Animals; Central Nervous System; Digestive System; Dose-Response Relationship, Radiation; Female; Hy

1990
Late functional and biochemical changes in mouse lung after irradiation: differential effects of WR-2721.
    Radiation research, 1985, Volume: 103, Issue:2

    Topics: Amifostine; Animals; Cesium Radioisotopes; DNA; Dose-Response Relationship, Radiation; Hydroxyprolin

1985
Collagen metabolism in mouse lung after X irradiation.
    Radiation research, 1987, Volume: 111, Issue:3

    Topics: Animals; Collagen; Fibrosis; Hydroxyproline; Lung; Mice; Protein Biosynthesis; Radiation Injuries, E

1987
Protection of acute and late radiation damage of the gastrointestinal tract by WR-2721.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:2

    Topics: Animals; Collagen; Colon; Digestive System; Dose-Response Relationship, Radiation; Hydroxyproline; J

1986
Vascular permeability and late radiation fibrosis in mouse lung.
    Radiation research, 1985, Volume: 103, Issue:1

    Topics: Albumins; Animals; Blood Proteins; Blood Volume; Capillary Permeability; Collagen; Female; Fibrin; F

1985
[Dose-time studies of radiogenic pneumopathy. IV. Hydroxyproline content of lung tissue of 60Co-gamma-irradiated young pigs].
    Radiobiologia, radiotherapia, 1985, Volume: 26, Issue:6

    Topics: Animals; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Gamma Rays; Hydroxyproline; Lu

1985
[Morphological and biochemical studies on the behavior of connective tissue in pulmonary fibrosis due to irradiation].
    Normale und pathologische Anatomie, 1973, Volume: 26

    Topics: Animals; Cobalt Isotopes; Collagen; Connective Tissue; Glycosaminoglycans; Histocytochemistry; Hydro

1973
[Change in the level of hydroxyproline-containing substances in blood and urine following irradiation].
    Meditsinskaia radiologiia, 1974, Volume: 19, Issue:3

    Topics: Animals; Electrons; Gamma Rays; Hydroxyproline; Radiation Injuries, Experimental; Rats

1974
Radiation injury of connective tissue. A biochemical investigation with experimental granuloma.
    Acta radiologica. Supplementum, 1973, Volume: 330

    Topics: Animals; Cell Division; Collagen; Connective Tissue; Connective Tissue Cells; Cytidine; DNA; Dose-Re

1973
Radiation and wound healing. A study of the gain of collagen content in the damaged skin of irradiated rats.
    Strahlentherapie, 1969, Volume: 138, Issue:3

    Topics: Animals; Collagen; Hydroxyproline; Male; Radiation Injuries, Experimental; Radioisotope Teletherapy;

1969
Lung connective tissue measurements. I. Amino acid analysis procedures for determination of canine lung connective tissue.
    Archives of internal medicine, 1971, Volume: 127, Issue:5

    Topics: Animals; Aspartic Acid; Autoanalysis; Chromatography, Ion Exchange; Collagen; Connective Tissue; Dog

1971
[Consequences of repeated whole body irradiation in rats].
    Strahlenschutz in Forschung und Praxis, 1968, Volume: 8

    Topics: Animals; Autoradiography; Hydroxyproline; Intestine, Small; Radiation Injuries, Experimental; Rats;

1968