hydroxyproline has been researched along with Experimental Neoplasms in 27 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tallysomycin S10b (TLM S10b), a structural analog of bleomycin (BLM), was evaluated and compared with BLM for antitumor activity in several murine tumor systems and for toxic effects in mice and rats." | 1.27 | Tallysomycin S10b: experimental antitumor activity and toxicity. ( Bradner, WT; Florczyk, AP; Hirth, RS; Huftalen, JB; Rose, WC; Schlein, A; Schurig, JE, 1984) |
| "The effects of three different dosage schedules on both therapeutic effect and pulmonary toxicity of bleomycin were studied in mice." | 1.26 | Improved therapeutic index of bleomycin when administered by continuous infusion in mice. ( Collins, JM; Gram, TE; Mimnaugh, EG; Sikic, BI, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (92.59) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Kang, G | 1 |
| Zhao, M | 1 |
| Wu, J | 1 |
| Zhang, X | 1 |
| Yang, Y | 1 |
| Liu, J | 1 |
| Peng, S | 1 |
| SHELTON, E | 1 |
| Sunila, ES | 1 |
| Kuttan, G | 1 |
| Fukumoto, M | 1 |
| Iguchi, H | 1 |
| Sawada, S | 1 |
| Midorikawa, O | 1 |
| Dubravsky, NB | 1 |
| Dubrawsky, C | 1 |
| Jampolis, S | 1 |
| Mason, K | 1 |
| Hunter, N | 1 |
| Withers, HR | 1 |
| Schurig, JE | 1 |
| Rose, WC | 1 |
| Hirth, RS | 1 |
| Schlein, A | 1 |
| Huftalen, JB | 1 |
| Florczyk, AP | 1 |
| Bradner, WT | 1 |
| Hirano, H | 1 |
| Urist, MR | 1 |
| Sikic, BI | 1 |
| Collins, JM | 1 |
| Mimnaugh, EG | 1 |
| Gram, TE | 1 |
| Nixon, JE | 1 |
| Wales, JH | 1 |
| Scanlan, RA | 1 |
| Bills, DD | 1 |
| Sinnhuber, RO | 1 |
| Vembu, D | 1 |
| Liotta, LA | 1 |
| Paranjpe, M | 1 |
| Boone, CW | 1 |
| Ko, CY | 1 |
| Johnson, LD | 1 |
| Priest, RE | 2 |
| Pan, QC | 1 |
| Guo, HY | 1 |
| Fleischmajer, R | 1 |
| Lara, JV | 1 |
| Gries, G | 1 |
| Lindner, J | 1 |
| Peringer, E | 1 |
| Seilern-Aspang, F | 1 |
| Mazzucco, K | 1 |
| Rajamäki, A | 1 |
| Kulonen, E | 1 |
| Harris, ED | 1 |
| Faulkner, CS | 1 |
| Wood, S | 1 |
| Bańkowski, E | 1 |
| Ratkiewicz, A | 1 |
| Galasiński W+GALASINSKI, W | 1 |
| Rzeczychi, W | 1 |
| Greenblatt, M | 2 |
| Kommineni, VR | 1 |
| Lijinsky, W | 2 |
| Nakagawa, H | 1 |
| Tsurufuji, S | 1 |
| Jackson, SH | 1 |
| Heininger, JA | 1 |
| Takeuchi, J | 1 |
| Pinto, JS | 1 |
| Dobson, RL | 1 |
| Bentley, JP | 1 |
| Bannister, DW | 1 |
| Carr, JG | 1 |
| Kowalewski, K | 1 |
27 other studies available for hydroxyproline and Experimental Neoplasms
| Article | Year |
|---|---|
A new platinum-complex showing easy preparation, promising anti-tumor activity, and better efficacy and distribution properties than oxaliplatin.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Proliferation; Drug Screening As | 2011 |
EFFECT OF TUMOR CELLS ON PRE-EXISTING COLLAGEN AND ON COLLAGEN PRODUCTION BY NORMAL CELLS GROWN IN DIFFUSION CHAMBERS.
Topics: Animals; Collagen; Connective Tissue; DNA; DNA, Neoplasm; Hydroxyproline; Mice; Neoplasms; Neoplasms | 1964 |
A preliminary study on antimetastatic activity of Thuja occidentalis L. in mice model.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; gamma | 2006 |
Collagen fibrillogenic activity in mouse mesenchymal tumor tissues and cells.
Topics: Animals; Cell Line; Collagen; Fibroblasts; Fibrosarcoma; Hydroxyproline; Male; Mice; Mice, Nude; Neo | 1980 |
Long-term effects of pulmonary damage in mice on lung weight, compliance, hydroxyproline content and formation of metastases.
Topics: Animals; Bleomycin; Fibrosarcoma; Hydroxyproline; Lung; Lung Compliance; Lung Neoplasms; Mice; Mice, | 1981 |
Tallysomycin S10b: experimental antitumor activity and toxicity.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Lung; Mice; Mice, Inbred Strains; Neoplasms, Experimen | 1984 |
Characteristics of the newly derived human chondrosarcoma cell line OSHU-1: observations on osteoinduction.
Topics: Animals; Bone Neoplasms; Cell Line; Chondrosarcoma; Humans; Hydroxyproline; Male; Mice; Mice, Nude; | 1980 |
Improved therapeutic index of bleomycin when administered by continuous infusion in mice.
Topics: Animals; Bleomycin; Dose-Response Relationship, Drug; Hydroxyproline; Lung; Lung Neoplasms; Male; Mi | 1978 |
Null carcinogenic effect of large doses of nitrosoproline and nitrosohydroxyproline in Wistar rats.
Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Synergism; Fatty Acids, Unsaturated; H | 1976 |
Correlation of tumorigenicity with resistance to growth inhibition by cis-hydroxypyroline.
Topics: Animals; Cell Division; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cell Transformati | 1979 |
Isolation and characterization of hydroxyproline-containing proteins secreted by a murine carcinoma cell culture.
Topics: Animals; Carcinoma; Cells, Cultured; Chromatography, Gel; Hydroxyproline; Mice; Molecular Weight; Ne | 1979 |
The potentiation of the antitumor activity but not toxicity of bleomycin by 3-aminobenzamide.
Topics: Animals; Benzamides; Bleomycin; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Hydro | 1989 |
The connective tissue in mice and rabbits in experimental carcinogenesis.
Topics: Animals; Carcinoma, Basal Cell; Hexosamines; Hexoses; Histocytochemistry; Hydroxyproline; Male; Meth | 1966 |
[Investigations on the effect of thyroid function on collagen metabolism].
Topics: Animals; Collagen; Glycosaminoglycans; Gossypium; Granuloma; Hydroxyproline; Hyperthyroidism; Neopla | 1966 |
[Difference between the collagenase-induced catabolic rate of tail and dorsal skin collagen of mice in relation to cancer induction].
Topics: Animals; Collagen; Hydroxyproline; Mice; Microbial Collagenase; Neoplasms, Experimental; Skin; Tail | 1970 |
Purification on a structural glycoprotein from collagenase-digested experimental granuloma.
Topics: Amino Acids; Animals; Cellulose; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatogra | 1971 |
Collagenase in carcinoma cells.
Topics: Animals; Carcinoma; Centrifugation; Culture Media; Culture Techniques; Dactinomycin; DNA, Neoplasm; | 1972 |
Insoluble collagen of the Guerin epithelioma.
Topics: Animals; Carcinoma, Squamous Cell; Collagen; Hexosamines; Hydrolysis; Hydroxyproline; Neoplasm Prote | 1974 |
Null effect of concurrent feeding of sodium nitrite and amino acids to MRC rats.
Topics: Amino Acids; Animals; Arginine; Diet; Female; Hydroxyproline; Male; Neoplasms, Experimental; Nitrite | 1973 |
Formation of epithelial basement membrane is restricted by scurvy in vitro and is stimulated by vitamin C.
Topics: Ascorbic Acid; Basement Membrane; Culture Media; Culture Techniques; Epithelium; Fluorescent Antibod | 1970 |
Action of betamethasone disodium phosphate on the metabolism of collagen and noncollagen protein in rat carrageenin granuloma.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Biodegradation, Environmental; Body Weight; Carrag | 1972 |
Failure to induce tumors in Swiss mice after concurrent administration of amino acids and sodium nitrite.
Topics: Adenoma; Animals; Arginine; Carcinogens; Female; Hydroxyproline; Lung Neoplasms; Male; Mice; Neoplas | 1972 |
Collagen reutilization in normal and hypersomatotrophic rats.
Topics: Animals; Collagen; Female; Granulation Tissue; Granuloma; Growth Hormone; Hydroxyproline; Hyperpitui | 1971 |
[Effect of chondroitin sulfate on the growth of solid Ehrlich ascites tumor under the influences of collagent, L-hydroxyproline and fibrinogen].
Topics: Animals; Carcinoma, Ehrlich Tumor; Chondroitin; Collagen; Dentistry; Fibrinogen; Hydroxyproline; Neo | 1968 |
Dermal collagen changes during 2-aminoanthracene carcinogenesis in the rat.
Topics: Animals; Benz(a)Anthracenes; Collagen; Hydroxyproline; Male; Neoplasms, Experimental; Proline; Rats; | 1970 |
The effect of induced neoplasms on levels of L-hydroxyproline in plasma of the domestic fowl.
Topics: Animals; Binding Sites; Chickens; Collagen; Connective Tissue; Hydroxyproline; Male; Mesenchymoma; M | 1971 |
Effect of chloroquine on tissue hydroxyproline and hexosamine in mice bearing Bashford carcinoma.
Topics: Animals; Carcinoma; Chloroquine; Hexosamines; Hydroxyproline; Male; Mice; Neoplasms, Connective Tiss | 1967 |