hydroxyproline has been researched along with Disease Models, Animal in 609 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Empagliflozin administered early after myocardial infarction reduce myocardial fibrosis and inhibit the TGF-β1/Smad3 fibrotic pathway, probably prior to exerting any hemodynamic or physiological effect." | 8.02 | The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats. ( Atar, S; Bandel, N; Daud, E; Ertracht, O; Moady, G; Reuveni, T; Shehadeh, M, 2021) |
| "Pirfenidone is known to slow the decline in vital capacity and increase survival in idiopathic pulmonary fibrosis (IPF)." | 7.88 | Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis. ( Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R, 2018) |
| " The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, attenuates dextran sulfate sodium (DSS)-induced colitis in mice." | 7.88 | Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress. ( Dai, Z; Ji, Y; Ma, X; Sun, S; Tso, P; Wu, G; Wu, Z; Yang, Y, 2018) |
| " Although hyperleptinemia is usually a characteristic of obese subjects, the relationship with atrial fibrosis and AF is unknown." | 7.85 | Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation. ( Aoki, K; Fukui, A; Fukunaga, N; Ikebe-Ebata, Y; Kondo, H; Masaki, T; Saito, S; Shinohara, T; Takahashi, N; Teshima, Y, 2017) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 7.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 7.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| "To evaluate the role of low molecular chitosan containing sepia ink (LMCS) in ethanol-induced (5 ml/kg) gastric ulcer in rats." | 7.83 | Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats. ( Li, L; Li, Y; Liu, K; Rao, Y; Sui, X; Wu, J; Wu, Q; Zhang, W, 2016) |
| "This study aimed to investigate the effects of L-carnitine, with its known antioxidant properties and positive effects on wound healing, on the healing of colon anastomosis in a cecal ligation and puncture sepsis model in rats." | 7.81 | The Effect of Systemic Carnitine Administration on Colon Anastomosis Healing in an Experimental Sepsis Model. ( Çikman, Ö; Ercan, U; Karaayvaz, M; Kilinç, N; Kiraz, A; Kiraz, HA; Otkun, MT; Özkan, ÖF; Türkön, H, 2015) |
| "9% intraperitoneally and those of group 3 (iloprost), and group 4 (ileus + iloprost) iloprost (2 μg/kg of body weight), immediately postoperatively and daily until the day of sacrifice." | 7.80 | The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions. ( Galanopoulos, G; Kanellos, I; Lazarides, C; Mantzoros, I; Pramateftakis, MG; Raptis, D, 2014) |
| "In order to decrease the risks originating from impaired mechanisms due to intra-abdominal sepsis, and to make anastomosis safer, combined use of glutamine and GH increases the bursting pressure of anastomosis." | 7.79 | The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model. ( Atamanalp, SS; Donmez, R; Kisaoglu, A; Oren, D; Ozogul, B; Ozturk, G, 2013) |
| "Metoclopramide is often used in the treatment of postoperative nausea and vomiting, but a literature review failed to find reports on the influence of this drug on the healing of bowel anastomoses in the setting of abdominal sepsis." | 7.79 | Effects of metoclopramide on healing of colonic anastomoses in a rat model of abdominal sepsis. ( Carneiro, FP; Ferreira, VM; Marques e Silva, S; Oliveira, PG; Sousa, JB, 2013) |
| "To study the use of bosentan to treat acute lung injury and pulmonary fibrosis as induced by paraquat." | 7.79 | Using bosentan to treat paraquat poisoning-induced acute lung injury in rats. ( Jian, X; Wang, J; Zhang, W; Zhang, Z; Zhou, Q, 2013) |
| "This study was designed to evaluate the effects of ethyl pyruvate (EP) on wound healing in primary colonic anastomoses in intraperitoneal sepsis." | 7.78 | Ethyl pyruvate improves healing of colonic anastomosis in a rat model of peritonitis. ( Akalin, B; Altun, H; Aydin, MT; Ekci, B; Karip, AB; Memisoglu, K; Onur, E, 2012) |
| "We evaluated the antifibrotic effects of pomalidomide in preventive as well as therapeutic treatment regimes using bleomycin-induced dermal fibrosis as a model of early, inflammatory stages of fibrosis and the tight-skin mouse model as a model of later stages of fibrosis with endogenous activation of fibroblasts." | 7.78 | Pomalidomide is effective for prevention and treatment of experimental skin fibrosis. ( Beyer, C; Cedzik, D; Dees, C; Distler, A; Distler, JH; Distler, O; Palumbo-Zerr, K; Schafer, PH; Schett, G; Shankar, SL; Tomcik, M; Weingärtner, S; Zerr, P, 2012) |
| "The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate." | 7.77 | Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011) |
| " We hypothesized that simvastatin will improve these dynamics in experimental hypercholesterolemia (HC)." | 7.77 | Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. ( Bonetti, PO; Herrmann, J; Lavi, R; Lerman, A; Lerman, LO; Mannheim, D, 2011) |
| "Several animal species are used to study calcium oxalate urolithiasis; however, an ideal model has yet to be identified." | 7.77 | Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis. ( Chang, CH; Chen, HY; Chen, WC; Chen, YH; Lee, YJ; Lin, WY; Liu, HP; Tsai, FJ, 2011) |
| " In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP)." | 7.76 | Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model. ( Crenshaw, TD; Darriet, C; Kaplon, DM; Nakada, SY; Penniston, KL, 2010) |
| "Metabolites of arachidonic acid such as prostacyclin (PGI2) have been shown to participate in the pathogenesis of pulmonary fibrosis by inhibiting the expression of pro-inflammatory and pro-fibrotic mediators." | 7.76 | A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice. ( Gao, J; Guo, Z; Huang, K; Jiang, L; Liu, Y; Xiang, R; Xiao, Y; Zhou, W; Zhu, Y, 2010) |
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 7.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 7.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| "To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)." | 7.74 | [Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008) |
| "To observe the effect of tyrosine kinase depressor imatinib mesylate on pulmonary fibrosis (PF) induced by bleomycin in mice and explore its mechanism." | 7.74 | [Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice]. ( Li, L; Li, YQ, 2007) |
| "The most common cause of death from poisoning by the widely used, but highly toxic herbicide paraquat is respiratory failure from pulmonary fibrosis, which develops through pathological overproduction of extracellular matrix proteins such as the collagens." | 7.74 | An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T, 2007) |
| "Rats receiving hydroxy-L-proline showed hyperoxaluria, calcium oxalate crystalluria and nephrolithiasis, and by day 42 all contained renal calcium oxalate crystal deposits." | 7.74 | Dietary oxalate and calcium oxalate nephrolithiasis. ( Byer, KJ; Glenton, PA; Khan, SR, 2007) |
| "To investigate the dynamic expression of placenta growth factor (PLGF) in the lungs with paraquat (PQ)-induced pulmonary fibrosis." | 7.74 | [Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model]. ( Dai, MS; Lin, LF; Zheng, MH, 2007) |
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 7.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| "The higher bursting pressures and tissue hydroxyproline levels in the rats given taurolidine showed the positive effect of taurolidine on anastomotic strength in secondary peritonitis." | 7.73 | Effect of peritoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis. ( Akkuş, A; Barişik, NO; Bildik, N; Cevik, A; Gülmen, M; Oztürk, E; Sad, O, 2006) |
| "To evaluate the efficacy of sustained-release cis-4-hydroxyproline (CHP), a proline analog that inhibits collagen secretion, on experimental proliferative vitreoretinopathy (PVR) in rabbits." | 7.71 | Sustained release of cis-hydroxyproline in the treatment of experimental proliferative vitreoretinopathy in rabbits. ( Honda, Y; Kimura, H; Miyamoto, H; Ogura, Y; Tabata, Y; Yasukawa, T, 2002) |
| "Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure." | 7.71 | Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002) |
| "To study the effects of panax notoginside (PNS) and methylprednisolone (solu-medrol) on the development of pulmonary fibrosis and the possible underlining mechanisms." | 7.71 | [The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis]. ( Cui, S; Li, X, 2002) |
| "We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)." | 7.71 | Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002) |
| "Oxaceprol, an established drug for treatment of degenerative joint disease, has recently been shown in vitro to reduce leukocyte adhesion to cultured endothelial cells and leukocyte extravasation in vivo in an arthritis animal model." | 7.70 | Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury. ( Harris, A; Messmer, K; Schropp, A, 1998) |
| "It was first reported in China that injection of a low dose of D-galactose into mice could induce changes which resembled accelerated aging." | 7.70 | Advanced glycation in D-galactose induced mouse aging model. ( Bao, M; Li, D; Li, YM; Song, X, 1999) |
| "The objective of this study was to evaluate the effectiveness of erythromycin (EM) on bleomycin-induced pulmonary fibrosis in rats and its possible mechanisms." | 7.69 | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. ( Chen, B; Hou, XM; Jiang, L; Yu, R; Zhao, W, 1997) |
| "We studied the inhibitory effects of tranilast, an anti-allergic drug, on the human keloid tissues implanted into the dorsal skin of athymic nude mice and on the growth of keloid fibroblast in vitro." | 7.68 | [Effect of tranilast, an anti-allergic drug, on the human keloid tissues]. ( Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O, 1992) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 7.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| "An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days." | 7.66 | Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 5.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "Pulmonary fibrosis is a common outcome of various interstitial lung diseases." | 5.48 | Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway. ( He, Y; Jiang, Z; Liu, H; Mei, J; Shen, S; Tang, M, 2018) |
| "Pulmonary fibrosis is a progressive lung disorder with high mortality rate and limited successful treatment." | 5.43 | Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9. ( Abuelezz, SA; Hendawy, N; Osman, WM, 2016) |
| "Hyperoxaluria was induced in male Sprague-Dawley rats by feeding hydroxyl-L-proline." | 5.40 | Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys. ( Khan, A; Khan, SR; Wang, W, 2014) |
| "Currently, there is no satisfactory treatment for pulmonary fibrosis, and effective agents urgently need to be developed." | 5.39 | Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. ( Chen, Y; Gao, Y; Gu, Z; Jiang, X; Lu, J; Zhang, Y, 2013) |
| "Hexarelin treatment significantly reduced cardiac fibrosis in SHRs by decreasing interstitial and perivascular myocardial collagen deposition and myocardial hydroxyproline content and reducing mRNA and protein expression of collagen I and III in SHR hearts." | 5.38 | Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. ( Cao, JM; Chen, C; Ding, F; Gao, X; Hao, W; Pang, J; Xu, RK; Xu, X, 2012) |
| "Pravastatin was given through intraperitoneal injection." | 5.36 | Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis. ( Kim, JW; Kim, KH; Kim, SC; Kim, TJ; Kim, YH; Kim, YK; Kwon, SS; Lee, SH; Lee, SY; Rhee, CK; Yoon, HK, 2010) |
| "Pyrrolidine dithiocarbamate (PDTC) is a low-molecular-weight thiol antioxidant and potent inhibitor of nuclear factor-kappaB (NF-kappaB) activation." | 5.34 | Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats. ( Aydin, C; Aytekin, FO; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Tekin, K; Yenisey, C, 2007) |
| "Fibrosis is a common pathological feature observed in muscle from patients with Duchenne muscular dystrophy and in mdx diaphragm." | 5.33 | Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle. ( Gosselin, LE; Williams, JE, 2006) |
| "Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis." | 5.33 | Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006) |
| "Lung inflammation was measured by quantitative differential evaluation of lung lavage cells." | 5.32 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. ( Kenyon, NJ; Last, JA; Pinkerton, KE; Temple, L; Ward, R, 2004) |
| "Treatment with pirfenidone significantly reduced the number of these cells compared with the corresponding BL group." | 5.32 | Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis. ( Abe, K; Fujii, T; Hayashi, T; Ishii, H; Kadota, J; Kakugawa, T; Kohno, S; Miyazaki, M; Mukae, H; Oku, H, 2004) |
| "Colchicine treatment was associated with increased interstitium in WKY with increased passive myocardial stiffness." | 5.30 | Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat. ( Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Hayes, JA; Robinson, KG; Sen, S, 1997) |
| "Pirfenidone (PFD) is a novel anti-fibrotic agent that can prevent and even reverse extracellular matrix accumulation in several organs, as shown by experimental and clinical studies." | 5.30 | Pirfenidone improves renal function and fibrosis in the post-obstructed kidney. ( Fukagawa, M; Hata, S; Kuroda, T; Kurokawa, K; Margolin, SB; Shimizu, T, 1998) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 5.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "Osteomyelitis was induced artificially by injecting Staphylococcus aureus culture in the tibiae of young rabbits." | 5.28 | Excretion of urinary hydroxyproline in correlation with severity of induced osteomyelitis in rabbits. ( Abbas, HL, 1991) |
| " Urothelial degeneration, necrosis, ulcer, bleeding, edema, inflammation and mast cell count, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), myeloperoxidase (MPO), and hydroxyproline parameters were evaluated." | 4.31 | Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model. ( Abdullah, A; Çiğdem, Y; Erhan, A; Tuğrul, EE, 2023) |
| "CAE oral administration lowered hydroxyproline content, inhibited the collagen deposition including expressions of collagen I and III, and relieved bleomycin-induced pulmonary fibrosis in mice model." | 4.02 | Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis. ( Chen, XY; Feng, FC; He, HL; Li, RF; Xu, Y; Zhou, XM, 2021) |
| "Empagliflozin administered early after myocardial infarction reduce myocardial fibrosis and inhibit the TGF-β1/Smad3 fibrotic pathway, probably prior to exerting any hemodynamic or physiological effect." | 4.02 | The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats. ( Atar, S; Bandel, N; Daud, E; Ertracht, O; Moady, G; Reuveni, T; Shehadeh, M, 2021) |
| "To evaluate the immune regulatory and anti-fibrosis function of thalidomide (Thal) in systemic sclerosis (SSc), we investigated the effects of Thal on: (a) Th17 and Treg cell production; (b) related factors expression; and (c) transforming growth factor (TGF)-β1/Smad3 pathway, using a mouse model of SSc." | 3.96 | Effects of thalidomide on Th17, Treg cells and TGF-β1/Smad3 pathway in a mouse model of systemic sclerosis. ( Lei, L; Li, X; Lu, Y; Tao, Z; Wen, J; Zhao, C; Zheng, L, 2020) |
| " After observing the pulmonary function indexes of the rats on the 3rd, 7th and 14th days after modeling, the rats were sacrificed by cervical dislocation, the pulmonary inflammation and fibrosis of the rats were observed, and the HYP (hydroxyproline) content and miR-223 expression level were determined." | 3.96 | Expression and significance of miR-223 in rats with pulmonary fibrosis. ( Ju, P; Li, YM; Qu, SJ; Shen, WP; Song, ZZ; Zhao, L, 2020) |
| "Pirfenidone is known to slow the decline in vital capacity and increase survival in idiopathic pulmonary fibrosis (IPF)." | 3.88 | Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis. ( Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R, 2018) |
| " In vivo, intratracheal treatment with Lv-miR-29c significantly increased expression of miR-29c, and reduced expression of β-catenin, matrix metalloproteinase (MMP)-2, and MMP-9 in the lung and levels of transforming growth factor-beta 1 (TGF-β1) and interleukin-6 (IL-6) in bronchoalveolar lavage fluid, and notably attenuated pulmonary fibrosis as evidenced by hydroxyproline content in silica-administered mice." | 3.88 | Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice. ( Liu, J; Wang, FS; Wang, X; Xu, K; Yang, XY; Zeng, Q, 2018) |
| " Fourth, hydroxyproline concentration decreased in the left ventricle and hypertension was normalised." | 3.88 | Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model. ( Chicco, A; Creus, A; Ferreira, MR; Lombardo, YB; Oliva, ME, 2018) |
| " The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, attenuates dextran sulfate sodium (DSS)-induced colitis in mice." | 3.88 | Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress. ( Dai, Z; Ji, Y; Ma, X; Sun, S; Tso, P; Wu, G; Wu, Z; Yang, Y, 2018) |
| " Although hyperleptinemia is usually a characteristic of obese subjects, the relationship with atrial fibrosis and AF is unknown." | 3.85 | Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation. ( Aoki, K; Fukui, A; Fukunaga, N; Ikebe-Ebata, Y; Kondo, H; Masaki, T; Saito, S; Shinohara, T; Takahashi, N; Teshima, Y, 2017) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 3.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 3.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| "Zofenopril partially prevented the increase in systolic blood pressure and cardiac hypertrophy induced by angiotensin II and avoided the increase in collagen deposition." | 3.83 | Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition. ( Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA, 2016) |
| "To evaluate the role of low molecular chitosan containing sepia ink (LMCS) in ethanol-induced (5 ml/kg) gastric ulcer in rats." | 3.83 | Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats. ( Li, L; Li, Y; Liu, K; Rao, Y; Sui, X; Wu, J; Wu, Q; Zhang, W, 2016) |
| "This study aimed to investigate the effects of L-carnitine, with its known antioxidant properties and positive effects on wound healing, on the healing of colon anastomosis in a cecal ligation and puncture sepsis model in rats." | 3.81 | The Effect of Systemic Carnitine Administration on Colon Anastomosis Healing in an Experimental Sepsis Model. ( Çikman, Ö; Ercan, U; Karaayvaz, M; Kilinç, N; Kiraz, A; Kiraz, HA; Otkun, MT; Özkan, ÖF; Türkön, H, 2015) |
| "Histological analysis and hydroxyproline assay revealed that bleomycin successfully induced pulmonary fibrosis, and that 20 μg of oral E4 peptide ameliorated the fibrosis." | 3.81 | An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model. ( Feghali-Bostwick, C; Mlakar, L; Nishimoto, T; Takihara, T, 2015) |
| "9% intraperitoneally and those of group 3 (iloprost), and group 4 (ileus + iloprost) iloprost (2 μg/kg of body weight), immediately postoperatively and daily until the day of sacrifice." | 3.80 | The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions. ( Galanopoulos, G; Kanellos, I; Lazarides, C; Mantzoros, I; Pramateftakis, MG; Raptis, D, 2014) |
| " Our results showed that DMN-induced hepatic pathological damage significantly decreased the body weight and liver index, increased the mRNA and protein levels of collagen α-1(I) (ColIα-1) and α-smooth muscle actin, and increased the hydroxyproline content." | 3.80 | Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation. ( Chen, CM; Chen, HL; Cheng, WT; Chong, KY; Tang, TY; Tung, YT; Yang, SH, 2014) |
| " The granuloma area, hepatic hydroxyproline (HYP) level and hepatic fibrosis of the protein therapeutic groups were significantly smaller than those of the positive control group (P<0." | 3.80 | The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease. ( Chu, D; Yao, Y; Zhou, C, 2014) |
| "In order to decrease the risks originating from impaired mechanisms due to intra-abdominal sepsis, and to make anastomosis safer, combined use of glutamine and GH increases the bursting pressure of anastomosis." | 3.79 | The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model. ( Atamanalp, SS; Donmez, R; Kisaoglu, A; Oren, D; Ozogul, B; Ozturk, G, 2013) |
| "Metoclopramide is often used in the treatment of postoperative nausea and vomiting, but a literature review failed to find reports on the influence of this drug on the healing of bowel anastomoses in the setting of abdominal sepsis." | 3.79 | Effects of metoclopramide on healing of colonic anastomoses in a rat model of abdominal sepsis. ( Carneiro, FP; Ferreira, VM; Marques e Silva, S; Oliveira, PG; Sousa, JB, 2013) |
| "Anti-KL-6 antibody significantly reduced the number of alveolar inflammatory leukocytes (total and differential counts) in BALF of mice with bleomycin-induced pulmonary fibrosis as well as the content of hydroxyproline in the lung tissues." | 3.79 | Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6. ( Bian, W; Ding, F; Gu, J; Rong, Z; Shen, C; Xu, L; Yang, D; Zhu, S, 2013) |
| "To study the use of bosentan to treat acute lung injury and pulmonary fibrosis as induced by paraquat." | 3.79 | Using bosentan to treat paraquat poisoning-induced acute lung injury in rats. ( Jian, X; Wang, J; Zhang, W; Zhang, Z; Zhou, Q, 2013) |
| "We previously reported hyperoxaluria and calcium oxalate calculi in adult pigs (sows) fed hydroxyproline (HP)." | 3.79 | Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model. ( Crenshaw, TD; Nakada, SY; Penniston, KL; Sehgal, PD; Sivalingam, S, 2013) |
| " Animal survival, body weight, hydroxyproline content in the lungs, lung histology, mRNA, and protein expression were studied." | 3.79 | Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2. ( Garbuzenko, OB; Ivanova, V; Minko, T; Pozharov, VP; Reimer, DC; Reuhl, KR, 2013) |
| "The purpose of our study was to determine if a hydroxyproline (HP) or gelatin diet could induce long-term hyperoxaluria in the porcine model." | 3.78 | Dietary induction of long-term hyperoxaluria in the porcine model. ( Crenshaw, TD; Iwicki, L; Nakada, SY; Patel, SR; Penniston, KL; Saeed, I, 2012) |
| "Cohorts of animals were culled at 3, 7, 14 and 28 days to semi-quantitatively score the lung for fibrosis, and quantitate levels of hydroxyproline in the lung." | 3.78 | Assessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography. ( Dickinson, H; Jenkin, G; Lim, R; Milton, PL, 2012) |
| " We investigated whether compound 21 alone or in combination with angiotensin II type 1 receptor blockade by olmesartan medoxomil could prevent PWV increase and aortic remodeling in N(ω)-nitro-L-arginine-methyl ester (L-NAME)-induced hypertension." | 3.78 | Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling. ( Baulmann, J; Becker, ST; Dahlöf, B; Kaschina, E; Lucht, K; Paulis, L; Schwengel, K; Slavic, S; Steckelings, UM; Thöne-Reineke, C; Unger, T, 2012) |
| "This study was designed to evaluate the effects of ethyl pyruvate (EP) on wound healing in primary colonic anastomoses in intraperitoneal sepsis." | 3.78 | Ethyl pyruvate improves healing of colonic anastomosis in a rat model of peritonitis. ( Akalin, B; Altun, H; Aydin, MT; Ekci, B; Karip, AB; Memisoglu, K; Onur, E, 2012) |
| "We evaluated the antifibrotic effects of pomalidomide in preventive as well as therapeutic treatment regimes using bleomycin-induced dermal fibrosis as a model of early, inflammatory stages of fibrosis and the tight-skin mouse model as a model of later stages of fibrosis with endogenous activation of fibroblasts." | 3.78 | Pomalidomide is effective for prevention and treatment of experimental skin fibrosis. ( Beyer, C; Cedzik, D; Dees, C; Distler, A; Distler, JH; Distler, O; Palumbo-Zerr, K; Schafer, PH; Schett, G; Shankar, SL; Tomcik, M; Weingärtner, S; Zerr, P, 2012) |
| "In this experimental model of caustic esophageal stricture, dexpanthenol and Y-27632 significantly attenuated esophageal stricture formation." | 3.77 | Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury. ( Ceylan, H; Ceylan, NO; Demiryurek, AT; Tarakçıoğlu, M; Tutar, E; Yapici, S, 2011) |
| "Characteristics of thioacetamide (TAA)-induced liver cirrhosis in rat was observed for 120 days after TAA withdrawal as part of the radiobiological study of partial liver irradiation on TAA-induced cirrhotic rats." | 3.77 | A natural process of cirrhosis resolution and deceleration of liver regeneration after thioacetamide withdrawal in a rat model. ( Gu, K; Jiang, GL; Lai, ST; Liu, J; Ma, NY; Ren, ZG; Wang, J; Zhao, JD, 2011) |
| "The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate." | 3.77 | Improved methodology to induce hyperoxaluria without treatment using hydroxyproline. ( Garrett, MR; Hung, LY; Mandel, NS; Wiessner, JH; Wille, DF, 2011) |
| " We hypothesized that simvastatin will improve these dynamics in experimental hypercholesterolemia (HC)." | 3.77 | Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. ( Bonetti, PO; Herrmann, J; Lavi, R; Lerman, A; Lerman, LO; Mannheim, D, 2011) |
| "Several animal species are used to study calcium oxalate urolithiasis; however, an ideal model has yet to be identified." | 3.77 | Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis. ( Chang, CH; Chen, HY; Chen, WC; Chen, YH; Lee, YJ; Lin, WY; Liu, HP; Tsai, FJ, 2011) |
| " Histological examination, Sirius red staining, and measurement of the contents of hydroxyproline and malondialdehyde of the pancreas were performed to evaluate pancreatic damage and fibrosis." | 3.77 | Comparison of antioxidative and antifibrotic effects of α-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis. ( Du, YQ; Gao, J; Gong, YF; Gu, JJ; Hu, LH; Jiang, F; Li, ZS; Liao, Z; Man, XH, 2011) |
| "The present study was designed to determine whether atorvastatin reduced hypertension-induced cardiac remodeling and whether these effects involved Protein Kinase D (PKD) and Myocyte Enhancer Factor 2D (MEF2D), factors known to be implicated in cardiac hypertrophy and fibrosis." | 3.76 | Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats. ( Geng, J; Kang, W; Wang, W; Zhang, Y; Zhao, Z; Zhiming, GE, 2010) |
| " In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP)." | 3.76 | Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model. ( Crenshaw, TD; Darriet, C; Kaplon, DM; Nakada, SY; Penniston, KL, 2010) |
| "Metabolites of arachidonic acid such as prostacyclin (PGI2) have been shown to participate in the pathogenesis of pulmonary fibrosis by inhibiting the expression of pro-inflammatory and pro-fibrotic mediators." | 3.76 | A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice. ( Gao, J; Guo, Z; Huang, K; Jiang, L; Liu, Y; Xiang, R; Xiao, Y; Zhou, W; Zhu, Y, 2010) |
| "Ethylene glycol (EG) exposure is a common model for kidney stones, because animals accumulate calcium oxalate monohydrate (COM) in kidneys." | 3.76 | Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity. ( Li, Y; McLaren, MC; McMartin, KE, 2010) |
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 3.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 3.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " To test the hypothesis that the absence of TIMP-1 enhances allergic lung inflammation, airway hyperreactivity (AHR), and lung remodeling in asthma, we studied TIMP-1 null (TIMP-1 KO) mice and their WT controls using an ovalbumin (OVA) asthma model." | 3.75 | Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma. ( Aalinkeel, R; Blume, JW; Fang, YV; Knight, PR; Lachina, S; Mahajan, SD; Mullan, BA; Ohtake, PJ; Sands, MF; Schwartz, SA; Sykes, DE; Takyar, SS, 2009) |
| "This study was carried out in order to investigate the effects of epigallocatechin gallate (EGCG) on myocardial fibrosis and cell proliferation in cardiac hypertrophy." | 3.75 | EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy. ( Gu, ZL; Guo, CY; Sheng, R; Xie, ML; Zhou, WX, 2009) |
| " LVH was characterized by increases in the ratios of heart and left ventricular weights to body weight, increased myocyte cross-sectional areas, myocardial and perivascular fibrosis, and elevated cardiac hydroxyproline." | 3.75 | K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function. ( Gao, S; Long, CL; Wang, H; Wang, RH, 2009) |
| " Hyperoxaluria was induced by adding hydroxyproline (HP) to the drinking water." | 3.75 | Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains. ( Garrett, MR; Mandel, NS; Roman, RJ; Wiessner, JH, 2009) |
| " The analyses of the rat body weight, hydroxyproline levels in serum and lung, scores of alveolitis and fibrosis, as well as the expression of transforming growth factor-beta(1) (TGF-beta(1)) at the protein and the messenger ribonucleic acid (mRNA) levels in lung were performed." | 3.75 | Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis. ( He, CC; Huang, MM; Li, JX; Zhou, XM, 2009) |
| "The aim of this study was to assess the beneficial effects of simvastatin on cigarette smoke-induced small airway remodeling in rats." | 3.75 | Simvastatin attenuates experimental small airway remodelling in rats. ( Chen, L; Feng, YL; Huang, XY; Liu, DS; Ou, XM; Uhal, BD; Wang, K; Wang, T; Wang, X; Wen, FQ, 2009) |
| "Rat models of experimental hepatic fibrosis were established by injection with CCl(4); the treated rats received emodin via oral administration at a dosage of 20 mg/kg twice a week at the same time." | 3.75 | Emodin protects rat liver from CCl(4)-induced fibrogenesis via inhibition of hepatic stellate cells activation. ( Dong, MX; Geng, YT; Jia, Y; Li, CC; Li, XY; Liu, JC; Niu, YC; Zhang, YB; Zhou, L, 2009) |
| "To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)." | 3.74 | [Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008) |
| "The role of procoagulant factor X in a murine model of ovalbumin (OVA)-induced asthma was investigated." | 3.74 | Coagulation factor Xa modulates airway remodeling in a murine model of asthma. ( Castellino, FJ; Martin, JA; Ploplis, VA; Shinagawa, K, 2007) |
| "To observe the effect of tyrosine kinase depressor imatinib mesylate on pulmonary fibrosis (PF) induced by bleomycin in mice and explore its mechanism." | 3.74 | [Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice]. ( Li, L; Li, YQ, 2007) |
| "The most common cause of death from poisoning by the widely used, but highly toxic herbicide paraquat is respiratory failure from pulmonary fibrosis, which develops through pathological overproduction of extracellular matrix proteins such as the collagens." | 3.74 | An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T, 2007) |
| "Rats receiving hydroxy-L-proline showed hyperoxaluria, calcium oxalate crystalluria and nephrolithiasis, and by day 42 all contained renal calcium oxalate crystal deposits." | 3.74 | Dietary oxalate and calcium oxalate nephrolithiasis. ( Byer, KJ; Glenton, PA; Khan, SR, 2007) |
| "To investigate the dynamic expression of placenta growth factor (PLGF) in the lungs with paraquat (PQ)-induced pulmonary fibrosis." | 3.74 | [Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model]. ( Dai, MS; Lin, LF; Zheng, MH, 2007) |
| "Although paraquat (PQ) is widely known to induce pulmonary fibrosis, the molecular mechanisms are poorly understood." | 3.74 | Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats. ( Akahori, F; Kasahara, Y; Sakaguchi, K; Satomi, Y, 2007) |
| "We examined effects of the AT1 antagonist (AT1A) olmesartan medoxomil (olmesartan) and the AT2 antagonist (AT2A) PD-123319 on BLM-induced pulmonary fibrosis, which was evaluated by Ashcroft's pathological scoring and hydroxyproline content of lungs." | 3.74 | Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice. ( Fujimura, M; Ichikawa, Y; Inuzuka, K; Nakao, S; Nishizawa, Y; Tagami, A; Takato, H; Waseda, Y; Yasui, M, 2008) |
| " The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures." | 3.73 | Mitomycin C prevents strictures in caustic esophageal burns in rats. ( Başaklar, AC; Demirtola, A; Dinçer, S; Gülen, S; Kale, N; Karabulut, R; Poyraz, A; Sönmez, K; Türkyilmaz, Z, 2005) |
| "The mutant MCP-1 treated group inhibited early pancreatic inflammation and later pancreatic fibrosis histologically, and showed a decrease in serum MCP-1 concentration, intrapancreatic hydroxyproline, alpha-smooth muscle actin, and an increase in intrapancreatic amylase and protein content compared with the empty plasmid treated group." | 3.73 | Anti-monocyte chemoattractant protein 1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats. ( Arita, Y; Egashira, K; Gibo, J; Ito, T; Kaku, T; Kawabe, K; Nawata, H; Oono, T; Usui, M; Zhao, HF; Zhao, QW, 2005) |
| "An experimental study was performed to investigate the efficacy of colchicine in the prevention of fibrosis in the alkaline burn of the esophagus in rats." | 3.73 | Colchicine in experimental alkaline burns of the rat esophagus: an old drug, a new indication? ( Karaoglu, AO; Ozutemiz, O; Vardar, E; Yenisey, C; Yukselen, O; Yukselen, V, 2006) |
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 3.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| "The higher bursting pressures and tissue hydroxyproline levels in the rats given taurolidine showed the positive effect of taurolidine on anastomotic strength in secondary peritonitis." | 3.73 | Effect of peritoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis. ( Akkuş, A; Barişik, NO; Bildik, N; Cevik, A; Gülmen, M; Oztürk, E; Sad, O, 2006) |
| "This study sought to determine whether excess hepatic iron potentiates liver injury in the methionine choline-deficient (MCD) model of non-alcoholic fatty liver disease (NAFLD)." | 3.73 | Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease. ( Hall, Pde L; Kirsch, R; Marais, AD; Sijtsema, HP; Tlali, M, 2006) |
| " This study examines the activity of the antioxidant N-acetylcysteine on bleomycin-induced pulmonary fibrosis in rats with emphasis on the early inflammatory phase." | 3.72 | In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats. ( Blesa, S; Bulbena, O; Closa, D; Cortijo, J; Estrela, JM; Martinez-Losa, M; Morcillo, EJ; Prats, N; Serrano-Mollar, A, 2003) |
| " Intratracheal AM administration resulted in pulmonary fibrosis 21 days posttreatment, as evidenced by an increased hydroxyproline content and histological damage." | 3.72 | Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity. ( Brien, JF; Card, JW; Margolin, SB; Massey, TE; Racz, WJ, 2003) |
| " The effects of 900 MHz of radiation on fibrosis, lipid peroxidation, and anti-oxidant enzymes and the ameliorating effects of melatonin (Mel) were evaluated in rat skin." | 3.72 | Oxidative stress-mediated skin damage in an experimental mobile phone model can be prevented by melatonin. ( Akturk, O; Altuntas, I; Ayata, A; Mollaoglu, H; Ozguner, F; Yilmaz, HR, 2004) |
| "To evaluate the efficacy of sustained-release cis-4-hydroxyproline (CHP), a proline analog that inhibits collagen secretion, on experimental proliferative vitreoretinopathy (PVR) in rabbits." | 3.71 | Sustained release of cis-hydroxyproline in the treatment of experimental proliferative vitreoretinopathy in rabbits. ( Honda, Y; Kimura, H; Miyamoto, H; Ogura, Y; Tabata, Y; Yasukawa, T, 2002) |
| "Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure." | 3.71 | Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002) |
| "To study the effects of panax notoginside (PNS) and methylprednisolone (solu-medrol) on the development of pulmonary fibrosis and the possible underlining mechanisms." | 3.71 | [The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis]. ( Cui, S; Li, X, 2002) |
| "The combination of ACE inhibitor and ARB, independently of the hypotensive effect, improved LV phenotypic change and increased LV endothelin-1 production and collagen accumulation, diastolic dysfunction, and survival in a rat heart failure model more effectively than either agent alone, thereby providing solid experimental evidence that the combination of these 2 agents is more beneficial than monotherapy for treatment of heart failure." | 3.71 | Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure. ( Iwao, H; Izumi, Y; Kawano, H; Kim, S; Kimoto, M; Yoshiyama, M; Zhan, Y, 2001) |
| "We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)." | 3.71 | Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002) |
| "Oxaceprol, an established drug for treatment of degenerative joint disease, has recently been shown in vitro to reduce leukocyte adhesion to cultured endothelial cells and leukocyte extravasation in vivo in an arthritis animal model." | 3.70 | Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury. ( Harris, A; Messmer, K; Schropp, A, 1998) |
| " Fibrosis was associated with formation of granulomas, increase in lung hydroxyproline, and sustained increases in tissue tumor necrosis factor-alpha and transforming growth factor-beta." | 3.70 | Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses. ( Franco, L; Gomez, BL; Graybill, JR; Najvar, L; Restrepo, A; Restrepo, S, 1998) |
| "Abdominal aortic aneurysms (AAAs) are associated with chronic inflammation, disruption of medial elastin, and increased local production of elastolytic matrix metalloproteinases (MMPs)." | 3.70 | Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908). ( Chen, JJ; Curci, JA; Hendricks, RT; Liao, S; Martin, RL; Moore, G; Starcher, BC; Thompson, RW, 1999) |
| "It was first reported in China that injection of a low dose of D-galactose into mice could induce changes which resembled accelerated aging." | 3.70 | Advanced glycation in D-galactose induced mouse aging model. ( Bao, M; Li, D; Li, YM; Song, X, 1999) |
| "Bleomycin was subcutaneously injected every day in WBB6F1-W/W(V) and their normal littermate WBB6F1-+/+ mice for 4 weeks, and mice were analyzed for histological sclerosis, mast cell number, plasma histamine level, and hydroxyproline content." | 3.70 | Animal model of sclerotic skin. II. Bleomycin induced scleroderma in genetically mast cell deficient WBB6F1-W/W(V) mice. ( Katayama, I; Nishioka, K; Takagawa, S; Takahashi, Y; Yamamoto, T, 1999) |
| " Treatment with PC-SOD at 10 mg/kg significantly reduced the hydroxyproline content and fibrosis score." | 3.69 | Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice. ( Hori, Y; Horie, K; Hoshino, J; Miyauchi, S; Mizuno, S; Sekiguchi, T; Yamazaki, C, 1997) |
| "The objective of this study was to evaluate the effectiveness of erythromycin (EM) on bleomycin-induced pulmonary fibrosis in rats and its possible mechanisms." | 3.69 | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. ( Chen, B; Hou, XM; Jiang, L; Yu, R; Zhao, W, 1997) |
| " The effect of one such angiostatic treatment, cortisone combined with heparin, was tested in an in vivo model of granuloma-mediated cartilage degradation." | 3.68 | The use of angiostatic steroids to inhibit cartilage destruction in an in vivo model of granuloma-mediated cartilage degradation. ( Colville-Nash, PR; el-Ghazaly, M; Willoughby, DA, 1993) |
| "We studied the inhibitory effects of tranilast, an anti-allergic drug, on the human keloid tissues implanted into the dorsal skin of athymic nude mice and on the growth of keloid fibroblast in vitro." | 3.68 | [Effect of tranilast, an anti-allergic drug, on the human keloid tissues]. ( Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O, 1992) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 3.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| " The value of serum procollagen type III peptide to body weight integrated over time (Kt) correlated linearly with hepatic hydroxyproline content (r = 0." | 3.67 | The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. ( Appelman, HD; Hahn, EG; Henley, KS; Kim, KY; Peters, KM; Rush, BD; Ruwart, MJ; Schuppan, D; Vidmar, TJ; Wilkinson, KF, 1989) |
| "An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days." | 3.66 | Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979) |
| "Cows fed a balanced diet with the required amounts of calcium and phosphorus developed acute hypocalcemia and hypophosphatemia shortly after parturition, even in the presence of the a responsive parathyroid gland, when bone resorption was selectively inhibited by the prepartal administration of disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP)." | 3.65 | Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resportion. ( Black, HE; Capen, CC; Geho, WB; Potts, JT; Re, R; Yarrington, JT, 1976) |
| "And 47 medium chronic hepatitis B viral fibrosis patients were studied." | 2.70 | Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis. ( Cai, WM; Liu, RH; Weng, HL, 2001) |
| "Asthma is an inflammatory disease of airways, and the main trigger of asthma is allergic inflammation." | 1.72 | Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects. ( Athari, SS; Li, M; Li, Y; Wang, B; Wang, J; Wang, R, 2022) |
| "Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by irreversible fibrosis and destruction of the alveolar structure." | 1.72 | Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model. ( Hwang, DW; Ko, MK; Lee, M; Piao, C; Zhuang, C, 2022) |
| "Idiopathic pulmonary fibrosis is a chronic, fibrosing interstitial pneumonia that presents with various clinical courses and progression ranging from rapid to slow." | 1.62 | IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis. ( Fujitaka, K; Hamada, H; Hattori, N; Horimasu, Y; Iwamoto, H; Masuda, T; Miyamoto, S; Nakanishi, Y; Nakashima, T; Ohshimo, S; Sakamoto, S; Yamaguchi, K, 2021) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 1.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "The major clinical manifestation of the Primary Hyperoxalurias (PH) is increased production of oxalate, as a consequence of genetic mutations that lead to aberrant glyoxylate and hydroxyproline metabolism." | 1.56 | The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria. ( Buchalski, B; Challa, A; Fargue, S; Holmes, RP; Knight, J; Lowther, WT; Wood, KD, 2020) |
| "Ursodeoxycholic acid (UDCA) has been widely used in the treatment of primary biliary cholangitis (PBC) with chronic liver fibrosis, but its detailed mechanism remains unclear." | 1.56 | Ursodeoxycholic acid alleviates experimental liver fibrosis involving inhibition of autophagy. ( Chen, L; Chen, XZ; Wu, PB; Ye, HL; Zhang, G; Zhang, JW, 2020) |
| "MIA-602 reduced lung inflammation and fibrosis due to bleomycin." | 1.51 | Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin. ( Cai, R; Delcroix, G; Griswold, AJ; Jackson, RM; Lazerson, A; Mirsaeidi, M; Schally, AV; Wangpaichitr, M; Zhang, C, 2019) |
| " Meanwhile, increased serum hydroxyproline (HOP) and decreased serum hexosamine (HOM) concentration in mice were turned to the opposite trend with increasing dosage of SPS, thus leading to a high rate of HOM/HOP." | 1.51 | Beneficial contribution of a safflower (Carthamus tinctorius L.) polysaccharide on steroid-induced avascular necrosis of the femoral head in rats. ( Cui, D; Huang, S; Zhao, D, 2019) |
| "Damage associated with bleomycin-induced pulmonary fibrosis was alleviated by dermatan sulphate." | 1.51 | Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis. ( Gao, W; Li, W; Xu, J; Xu, S; Yu, Z, 2019) |
| "Idiopathic pulmonary fibrosis is characterized by loss of lung epithelial cells and inexorable progression of fibrosis with no effective and approved treatments." | 1.51 | Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice. ( Chen, M; Dong, M; Gao, Y; Han, L; Jin, F; Li, W; Lin, H; Shi, Y; Zhou, Y; Zuo, W, 2019) |
| "Hydroxyproline levels were found to be lower in each of the treatment groups as compared to the control group (p=0." | 1.51 | The protective and anti-inflammatory effect of methylene blue in corrosive esophageal burns: An experimental study. ( Bahadır, B; Can, M; Kefeli, A; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2019) |
| "Metformin (MET) has anti-inflammatory and anti-fibrotic effects, but its effect on the in vivo pathogenesis of scleroderma remains unknown." | 1.51 | Metformin attenuates bleomycin-induced scleroderma by regulating the balance of Treg/Teff cells and reducing spleen germinal center formation. ( Feng, M; Gao, C; Guo, H; Li, X; Liang, Z; Luo, J; Qin, K; Wang, Y; Zhang, S; Zhao, X, 2019) |
| "Phenytoin 1% ointment was used as a standard control." | 1.48 | Wound healing property of milk in full thickness wound model of rabbit. ( Hemmati, AA; Housmand, G; Jalali, A; Larki-Harchegani, A; Rezaei, A; Shabib, S, 2018) |
| "Pulmonary fibrosis is a debilitating disease and is often fatal." | 1.48 | Animal Models of Pulmonary Fibrosis. ( Moore, BB; O'Dwyer, DN, 2018) |
| "Pulmonary fibrosis is a common outcome of various interstitial lung diseases." | 1.48 | Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway. ( He, Y; Jiang, Z; Liu, H; Mei, J; Shen, S; Tang, M, 2018) |
| "The effect of MSC transplantation on lung injury was then evaluated 180 days after transplantation." | 1.48 | Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury. ( Dai, J; Dai, X; Fang, J; Feng, C; Hao, J; Hao, Y; Li, J; Li, R; Liu, J; Lu, B; Ma, R; Qiao, Z; Ran, Y; Xiong, W; Zhang, J; Zhou, Q, 2018) |
| "Pulmonary fibrosis is a multifaceted disease with high mortality and morbidity, and it is commonly nonresponsive to conventional therapy." | 1.48 | Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats. ( Ahad, A; Ahmad Ansari, M; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Ali, N; Khan, A; Raish, M, 2018) |
| "Intestinal fibrosis is thought to be a consequence of excessive tissue repair, and constitutes a common problem in patients with Crohn's disease (CD)." | 1.48 | Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis. ( Fagagnini, S; Hausmann, M; Hünerwadel, A; Jaeger, SU; Lutz, C; Mamie, C; Rogler, G; Ruiz, PA; Weder, B, 2018) |
| "The exploration of effective treatment for pulmonary fibrosis remains an urgent challenge." | 1.48 | A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice. ( Mao, M; Sun, L; Yan, Z; Zhang, X; Zuo, C, 2018) |
| "Liver fibrosis is a pathological process complicating schistosomiasis." | 1.46 | Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis. ( Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM, 2017) |
| "Fibrosis was assessed by measuring the liver hydroxyproline content." | 1.46 | Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans. ( Arauz, J; Favari, L; Galicia-Moreno, M; Hernández-Aquino, E; Muriel, P; Segovia, J; Zarco, N, 2017) |
| "BDL animal model of liver fibrosis was used in the study." | 1.46 | HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats. ( Debek, W; Hermanowicz, A; Lebensztejn, DM; Miltyk, W; Moczydlowska, J; Palka, JA, 2017) |
| "Carvedilol co-treatment in CCl4-intoxicated rats for 6 weeks significantly counteracted the changes in hepatotoxicity markers and histopathological lesions induced by CCl4." | 1.46 | Antifibrotic Effects of Carvedilol and Impact of Liver Fibrosis on Carvedilol Pharmacokinetics in a Rat model. ( Abdel-Sattar, SA; El-Bakly, WM; El-Demerdash, E; Mohamed, EA, 2017) |
| "To understand the mechanisms underlying pulmonary fibrosis and assess potential therapies, mouse models are central to basic and translational research." | 1.46 | Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis. ( Akinyi, TG; Cleveland, ZI; Davidson, CR; Dunn, RS; Guo, J; Hardie, WD; Woods, JC; Zhou, YM, 2017) |
| "Renal fibrosis is a well‑known cause for the progression of chronic kidney disease." | 1.43 | Partial deletion of the ROCK2 protein fails to reduce renal fibrosis in a unilateral ureteral obstruction model in mice. ( Baba, I; Egi, Y; Suzuki, K, 2016) |
| "Sepsis was induced by cecal ligation and puncture procedure." | 1.43 | The Effect of Platelet-Rich-Plasma on the Healing of Left Colonic Anastomosis in a Rat Model of Intra-Abdominal Sepsis. ( Cennet, A; Cetinkunar, S; Colak, T; Irkorucu, O; Polat, G; Reyhan, E; Sozutek, A, 2016) |
| "Pancreatic cancer is notorious for its poor prognosis." | 1.43 | Increased fibrosis and impaired intratumoral accumulation of macromolecules in a murine model of pancreatic cancer co-administered with FGF-2. ( Cabral, H; Iwata, C; Kano, MR; Miyazono, K; Morishita, Y; Sakai, S; Tanaka, HY, 2016) |
| "Pulmonary fibrosis is a progressive lung disorder with high mortality rate and limited successful treatment." | 1.43 | Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9. ( Abuelezz, SA; Hendawy, N; Osman, WM, 2016) |
| "Psoriasis was induced in Wistar rats by espousing 10% area of total body by UV radiations." | 1.43 | Evaluation of potent phytomedicine for treatment of psoriasis using UV radiation induced psoriasis in rats. ( Nagar, HK; Ranawat, MS; Srivastava, AK; Srivastava, R, 2016) |
| "Hydroxyproline levels were significantly lower in the sham (48." | 1.42 | Effect of intraperitoneal curcumin instillation on postoperative peritoneal adhesions. ( Alabalik, U; Avci, Y; Gül, M; Türkoğlu, A; Ülger, BV; Uslukaya, O; Yuksel, HK, 2015) |
| "Idiopathic pulmonary fibrosis is a chronic pulmonary disease that is characterized by formation of scar tissue in lungs." | 1.42 | Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis. ( Abdullah, M; Ho, CC; Koh, RY; Lim, CL; Seow, HF; Uhal, BD; Vidyadaran, S, 2015) |
| "A model of pressure overloaded ventricular remodeling was produced by abdominal aortic constriction (AAC) in rats." | 1.42 | The effect of angoroside C on pressure overload-induced ventricular remodeling in rats. ( Chen, CX; Gao, JP; Gu, WL; Huang, XY, 2015) |
| "The CCl4‑induced rats exhibited liver fibrosis, increased hydroxyproline content, impaired liver function, upregulated expression levels of the α‑SMA and TGF‑β1 pro‑fibrogenic proteins, and increased expression of HSP70, compared with the control group." | 1.42 | Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70. ( Chen, B; Chen, J; He, W; Qi, L; Shao, D; Wang, L; Wang, M; Zhuang, Y, 2015) |
| "Hyperoxaluria was induced in male Sprague-Dawley rats by feeding hydroxyl-L-proline." | 1.40 | Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys. ( Khan, A; Khan, SR; Wang, W, 2014) |
| "Pulmonary fibrosis is caused by excessive proliferation and accumulation of stromal cells." | 1.40 | Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis. ( Davidson, C; Edukulla, R; Hardie, WD; Ikegami, M; Madala, SK; Schmidt, S, 2014) |
| "Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with unknown etiology and undefined treatment modality." | 1.40 | CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis. ( Li, Y; Liang, C; Yang, W; Zhang, L, 2014) |
| "In the incision wound model, incision wounds were topically treated with TE gel (2." | 1.40 | Wound healing activity of the inflorescence of Typha elephantina (Cattail). ( Panda, V; Thakur, T, 2014) |
| "Hydroxyproline levels were higher in group M than in group C." | 1.40 | The use of collagen content as determined by spectral domain polarization-sensitive optical coherence tomography to assess colon anastomosis healing in a rat model. ( Ahn, CB; Jeong, HW; Jung, WW; Kim, BM; Kim, HS; Kim, KT; Lee, SH; Lee, SK; Park, KY; Son, KH, 2014) |
| "Idiopathic pulmonary fibrosis is a progressive and lethal disease, characterized by loss of lung elasticity and alveolar surface area, secondary to alveolar epithelial cell injury, reactive inflammation, proliferation of fibroblasts, and deposition of extracellular matrix." | 1.40 | Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230. ( Accart, N; Beckmann, N; Cannet, C; Dunbar, A; Egger, C; Gérard, C; Jarai, G; Jarman, E; Piaia, A; Schmid, HA; Tigani, B; Vidotto, N, 2014) |
| "We developed a mouse model of airway remodeling, which includes smooth muscle thickening, in which ovalbumin (OVA)-sensitized mice were repeatedly exposed to intranasal OVA administration twice a week for 3 months." | 1.40 | Effect of nilotinib on airway remodeling in a murine model of chronic asthma. ( Kang, JY; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2014) |
| "Hydroxyproline content was measured and histologic analysis was performed." | 1.40 | Ultrapure alginate anti-adhesion gel does not impair colon anastomotic strength. ( Chaturvedi, AA; Hendriks, T; Lomme, RM; van Goor, H, 2014) |
| "Advanced liver fibrosis results in cirrhosis and liver failure, and liver transplantation is often the only option for effective therapy; however, the shortage of available donor livers limits this treatment." | 1.40 | Therapeutic potential of amniotic-fluid-derived stem cells on liver fibrosis model in mice. ( Chen, YH; Cheng, PJ; Cheng, WT; Chou, CJ; Kao, YJ; Ko, IC; Peng, SY; Shaw, SW; Wu, SC, 2014) |
| "Pulmonary fibrosis was induced in Sprague-Dawley rats by BLM (5 mg/kg), killed 14 and 28 days after BLM administration by abdominal aorta exsanguination and removed the lungs." | 1.40 | Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats. ( Fei, GH; Gao, J; Li, LC; Li, P; Qi, LW; Xu, L; Zhao, P, 2014) |
| "Currently, there is no satisfactory treatment for pulmonary fibrosis, and effective agents urgently need to be developed." | 1.39 | Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. ( Chen, Y; Gao, Y; Gu, Z; Jiang, X; Lu, J; Zhang, Y, 2013) |
| "Pulmonary fibrosis is a serious and irreversible lung injury with obscure etiologic mechanisms and no effective treatment to date." | 1.39 | Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis. ( Bai, H; Chen, H; Hai, C; Li, W; Liang, X; Liu, R; Qin, X; Wang, X; Zhang, W; Zhang, X, 2013) |
| "However, the role of IL-17 in liver fibrosis has not yet been elucidated." | 1.39 | Interleukin-17A plays a pivotal role in cholestatic liver fibrosis in mice. ( Fujii, H; Furuya, S; Hara, M; Hirayama, K; Kono, H; Tsuchiya, M, 2013) |
| "LAMR1 mAb can evidently alleviate pulmonary fibrosis induced by bleomycin in rats." | 1.39 | [Monoclonal antibody against laminin receptor 1 inhibits the pulmonary fibrosis induced by bleomycin in rats]. ( Chen, D; Feng, Y; Han, X; Jiang, T; Zhou, M, 2013) |
| "Tendinopathy is a pathology found mainly in the rotator cuff, patellar, Achilles and flexor tendons." | 1.39 | Inflammatory process induced by carrageenan in adjacent tissue triggers the acute inflammation in deep digital flexor tendon of rats. ( Da Ré Guerra, F; De Almeida, Mdos S; De Aro, AA; De Oliveira, LP; Pimentel, ER; Vieira, CP, 2013) |
| "Hydroxyproline content was similar between mdx and control groups." | 1.39 | Mechanical and morphological aspects of the calcaneal tendon of mdx mice at 21 days of age. ( Camilli, JA; Nakagaki, WR; Pimentel, ER; Tomiosso, TC, 2013) |
| "Salvianolic acid B (Sal B) is a major water soluble component extracted from Radix Salviae miltiorrhizae, a traditional Chinese herb widely used for treating cardiovascular and hepatic diseases." | 1.39 | Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro. ( Fu, WW; Liu, CH; Shen, L; Tao, YY; Wang, QL, 2013) |
| "Thus, using HGF in gene therapy against liver fibrosis is an attractive approach." | 1.39 | Efficacy of HGF carried by ultrasound microbubble-cationic nano-liposomes complex for treating hepatic fibrosis in a bile duct ligation rat model, and its relationship with the diffusion-weighted MRI parameters. ( Li, WY; Wen, KM; Wu, W; Zhang, SH; Zhao, JN, 2013) |
| "The hydroxyproline (HYP) content was significantly decreased in the AF-1-treated mice." | 1.39 | Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice. ( Chen, Y; Cheng, QM; Feng, DD; Han, JZ; Huang, YH; Li, C; Li, Y; Liu, W; Luo, ZQ; Wan, J; Yue, SJ, 2013) |
| "1, 25 (OH) 2D3 was shown to reduce pulmonary fibrosis induced by bleomycin in mice, and its mechanisms might be associated with Wnt signaling suppression." | 1.39 | [Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice]. ( Fang, X; Gu, J; Gu, P; Qiu, WZ; Yi, XH; Zeng, Y; Zhang, L; Zhang, SX; Zhang, YD; Zhang, ZM; Zhu, XY, 2013) |
| "Pulmonary fibrosis was induced in C57BL/6 male mice by intratracheal instillation of bleomycin (5 mg." | 1.38 | The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice. ( Chai, Y; Dong, Z; Li, Y; Tai, W; Wang, D; Yang, Y; Zhang, T; Zhong, H; Zou, H, 2012) |
| "Chronic pancreatitis is a progressive inflammatory disease featuring irreversible irregular scarring of the exocrine parenchyma characterized by acinar destruction and fibrosis subsequent to inflammation in the pancreas." | 1.38 | Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice. ( Gao, J; Han, W; Qian, L; Shen, J; Wang, X; Wu, M; Xiang, D; Yang, L; Yu, Y; Zhang, J; Zhu, S, 2012) |
| "Kidney fibrosis is a common process that leads to the progression of various types of kidney disease." | 1.38 | A systems approach identifies HIPK2 as a key regulator of kidney fibrosis. ( Chen, EY; Chen, N; Chuang, PY; D'Agati, V; Dai, Y; Fan, Y; He, JC; Jin, Y; Ma'ayan, A; Mazloom, AR; Ratnam, K; Ross, MJ; Xiong, H; Zhong, Y, 2012) |
| "Advances in the treatment of smoke inhalation injury have been limited in the past years." | 1.38 | A rat model of smoke inhalation injury. ( Jin, Y; Lv, T; Qiu, X; Sun, Y; Wang, J; Xia, Z; Zhu, F, 2012) |
| "Molecular MRI of liver fibrosis with a collagen-specific probe identifies fibrotic tissue in two rodent models of disease." | 1.38 | Molecular MR imaging of liver fibrosis: a feasibility study using rat and mouse models. ( Alford, JK; Caravan, P; Fuchs, BC; Guimaraes, AR; Lauwers, GY; Loving, GS; Polasek, M; Schühle, DT; Tanabe, KK; Uppal, R; Wei, L; Yamada, S, 2012) |
| "Radiation-induced lung injury is one of the limiting factors for radiation therapy." | 1.38 | Protective effect of recombinant protein SOD-TAT on radiation-induced lung injury in mice. ( He, H; Hou, X; Liu, S; Pan, J; Rao, P; Su, Y; Wu, J, 2012) |
| "Hexarelin treatment significantly reduced cardiac fibrosis in SHRs by decreasing interstitial and perivascular myocardial collagen deposition and myocardial hydroxyproline content and reducing mRNA and protein expression of collagen I and III in SHR hearts." | 1.38 | Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. ( Cao, JM; Chen, C; Ding, F; Gao, X; Hao, W; Pang, J; Xu, RK; Xu, X, 2012) |
| "PF administration attenuated DMN-induced liver fibrosis at least in part by regulating macrophage disruption in the main organs." | 1.38 | Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats. ( Chen, X; Liu, C; Lu, L; Lu, Y; Lv, Z; Pan, Q; Xu, Q; Yang, Z, 2012) |
| "Topical application of JT on excision wounds caused significantly faster reduction in wound area as compared to the application of modern topical formulation (Neosporin(®)) and untreated control wounds." | 1.37 | Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model. ( Menon, S; Pednekar, S; Shailajan, S; Singh, A, 2011) |
| "Liver fibrosis was induced by intraperitoneal injection of 200 mg/kg body weight." | 1.37 | Hepatoprotective activity of a phytotherapeutic formula on thioacetamide--induced liver fibrosis model. ( Catanzaro, R; Jains, S; Kantah, MK; Kobayashi, R; Marotta, F; Minelli, E; Naito, Y; Polimeni, A; Solimene, U; Sollano, J, 2011) |
| "The hydroxyproline contents were investigated by spectrophotometric measurement." | 1.37 | [Protective effects of Leonurus japonicas on myocardial remodeling induced by isoproterenol in rats]. ( Gu, YP; Guo, W; Liu, Y; Lv, R; Wei, HC; Yuan, BP; Zhang, C, 2011) |
| "Hydroxyproline content was also significantly lower at 14 weeks in mice treated with taurine (P = 0." | 1.36 | Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice. ( Bouchier-Hayes, DJ; Condron, C; Moriarty, M; Robb, WB; Walsh, TN, 2010) |
| "Silicosis is a kind of pneumoconiosis caused by inhalation of silica dust, which is characterized by lung fibrosis." | 1.36 | A CD36 synthetic peptide inhibits silica-induced lung fibrosis in the mice. ( Chen, J; Chen, Y; Lv, L; Wang, X, 2010) |
| "Coffee exerts protective effects against liver fibrosis via antioxidant action and the suppression of fibrogenic cytokines, TGF-beta and PDGF-beta." | 1.36 | Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats. ( Kang, JK; Shin, JW; Son, CG; Wang, JH, 2010) |
| "Pravastatin was given through intraperitoneal injection." | 1.36 | Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis. ( Kim, JW; Kim, KH; Kim, SC; Kim, TJ; Kim, YH; Kim, YK; Kwon, SS; Lee, SH; Lee, SY; Rhee, CK; Yoon, HK, 2010) |
| "Fibrosis is the final common pathway for various tissue lesions that lead to chronic progressive organ failure, and consequently effective antifibrotic drugs are strongly desired." | 1.36 | A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. ( Kato, M; Mizuno, M; Sada, T; Terashima, H; Tsuchida, H; Yasumo, H, 2010) |
| "Hydroxyproline, which is an indicator of fibrosis in liver tissue, was high in the ethanol-treated control group." | 1.36 | Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride- and ethanol-induced hepatic damage. ( Firdous, AP; Kuttan, R; Preethi, KC; Sindhu, ER, 2010) |
| "Thalidomide, because of its anti-inflammatory properties, as re-emerged as an option for the treatment of Crohn's disease refractory to standard therapy." | 1.35 | Effect of thalidomide on the healing of colonic anastomosis, in rats. ( Campos, AD; Feres, O; Ramalho, FS; Ramalho, LN; Rocha, JJ; Veneziano, SG, 2008) |
| "To induce liver fibrosis, C57BL6 female mice were injected i." | 1.35 | Platelets contribute to the reduction of liver fibrosis in mice. ( Aoyagi, Y; Fukunaga, K; Hashimoto, I; Ikeda, O; Matsuo, R; Murata, S; Nakano, Y; Ohkohchi, N; Watanabe, M; Yasue, H, 2009) |
| "Hydroxyproline content was found to be significantly increased in the Group-III." | 1.35 | Wound healing properties of Carica papaya latex: in vivo evaluation in mice burn model. ( Gurung, S; Skalko-Basnet, N, 2009) |
| "Bacterial peritonitis was induced in all rats by performing a cecal ligation and puncture." | 1.35 | Effects of amniotic membrane on the healing of primary colonic anastomoses in the cecal ligation and puncture model of secondary peritonitis in rats. ( Citgez, B; Isgor, A; Ozcan, O; Ozkaya, O; Polat, N; Uludag, M; Yetkin, G, 2009) |
| "The incidence of pulmonary fibrosis increases with age." | 1.35 | Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice. ( Brigham, KL; Gonzalez, ET; Iyer, SS; Kelly, P; Mac, V; Mora, AL; Reed, A; Rojas, M; Sutliff, RL; Xu, J, 2009) |
| "The results suggested that rapid pulmonary fibrosis could be induced by ALI via LPS three-hits." | 1.35 | Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen. ( Chen, D; Chen, Y; Cui, Y; Du, S; Huang, W; Li, H; Li, Y; Wei, Z; Yang, J; Yang, L; Yao, Z; Zhang, R; Zhang, S; Zhou, J, 2009) |
| "Rolipram (0." | 1.35 | Rolipram attenuates bleomycin A5-induced pulmonary fibrosis in rats. ( Hou, YH; Pan, JB; Zhang, GJ, 2009) |
| "Clinical use of GGA for drug-induced pulmonary fibrosis might be considered in the future." | 1.35 | Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model. ( Fujibayashi, T; Hasegawa, Y; Hashimoto, N; Ishiguro, N; Jijiwa, M; Kojima, T, 2009) |
| "The development of pulmonary fibrosis includes inflammatory episodes." | 1.35 | Extracorporeal photopheresis in a rat model of pulmonary fibrosis. ( Boehler, A; Guo, Z; Hofer, M; Rechsteiner, T; Remund, K, 2009) |
| "Treatment of liver fibrosis associated with Schistosoma japonicum ova-induced granulomas remains a challenging proposition." | 1.35 | Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice. ( Li, X; Luo, Q; Shen, J; Wei, W; Wen, H; Zhong, Z, 2009) |
| "Idiopathic pulmonary fibrosis (IPF) is a treatment resistant disease with poor prognosis." | 1.35 | Comparison between conventional and "clinical" assessment of experimental lung fibrosis. ( Ask, K; Farkas, L; Farncombe, T; Froese, A; Gauldie, J; Inman, M; Kolb, MR; Labiris, R; McClelland, GB; Moeller, A, 2008) |
| "The currently accepted approaches to treatment of pulmonary fibrosis are based on the treatment of alveolitis and pulmonary fibrosis, however clinically available anti-inflammatory and antifibrotic agents are not often beneficial." | 1.34 | Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats. ( Hou, J; Li, JX; Zhang, GC; Zhou, XM, 2007) |
| "Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disorder of unknown cause." | 1.34 | Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. ( Brigham, K; Mora, AL; Ritzenthaler, J; Rojas, M; Roman, J; Speck, SH; Stecenko, A; Torres-González, E; Xu, J, 2007) |
| "Hydroxyproline was 504." | 1.34 | Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats. ( Cao, BQ; Chen, R; Huang, SB; Lin, JZ; Lin, N; Tang, ZF; Xiang, P; Xu, RY; Zhong, YS, 2007) |
| " Although a daily dosage of isoflavone was not sufficient to prevent tissue fibrosis under marked oxidative stress in the early stage of diabetes, isoflavones might promise significant clinical benefits by reducing oxidative stress in the heart during aging." | 1.34 | Inhibitory effects of soy isoflavones on cardiovascular collagen accumulation in rats. ( Ebihara, K; Kishida, T; Miyatake, A; Mizushige, K; Mizushige, T, 2007) |
| "Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis." | 1.34 | Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis. ( Accatino, L; Aguayo, G; Arrese, M; Duarte, I; Ibañez, P; Miquel, JF; Pizarro, M; Solis, N, 2007) |
| "Pyrrolidine dithiocarbamate (PDTC) is a low-molecular-weight thiol antioxidant and potent inhibitor of nuclear factor-kappaB (NF-kappaB) activation." | 1.34 | Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats. ( Aydin, C; Aytekin, FO; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Tekin, K; Yenisey, C, 2007) |
| "Hydroxyproline (HP) levels were significantly higher in control group than all other groups (P < 0." | 1.34 | Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions. ( Ariturk, E; Bernay, F; Bicakci, U; Kilicoglu-Aydin, B; Rizalar, R; Tander, B, 2007) |
| "Hydroxyproline and histology were not different between groups." | 1.34 | A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat. ( Bleichrodt, RP; Hendriks, T; Posma, LA; van Goor, H, 2007) |
| "Lung hydroxyproline content was increased in hyperoxia-exposed wild-type, but not in cat S-deficient lungs." | 1.34 | Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury. ( Bingol-Karakoc, G; Cataltepe, S; Hirakawa, H; Karaaslan, C; Mariani, TJ; Pierce, RA; Saad, A; Shapiro, SD; Shi, GP; Starcher, B; Weber, E; Weng, M, 2007) |
| "Pulmonary fibrosis is a progressive illness characterized by interstitial fibrosis." | 1.33 | Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma. ( Chung, DH; Chung, JH; Kim, HY; Kim, JH; Kim, S; Park, WS, 2005) |
| "Melatonin has direct and indirect free radical-detoxifying activity." | 1.33 | Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats. ( Erdogan, H; Fadillioglu, E; Iraz, M; Kotuk, M; Kuku, I; Yagmurca, M; Yildirim, Z, 2006) |
| "Sepsis was produced by cecal ligation and puncture." | 1.33 | [Does sepsis impair the healing of colonic anastomosis in splenectomized rats?]. ( Aksöyek, S; Avlan, D; Çıngı, E; Çömelekoğlu, Ü; Naycı, A; Renda, N; Taşkınlar, H, 2005) |
| "Hydroxyproline level was significantly higher (13." | 1.33 | Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats. ( Erdogan, H; Ermis, H; Fadillioğlu, E; Iraz, M; Kilic, T; Kotuk, M; Yağmurca, M; Yildirim, Z, 2006) |
| "Fibrosis is a common pathological feature observed in muscle from patients with Duchenne muscular dystrophy and in mdx diaphragm." | 1.33 | Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle. ( Gosselin, LE; Williams, JE, 2006) |
| "Ethylene glycol (EG)-induced hyperoxaluria in rats is most common, but is criticized because EG and some of its metabolites are nephrotoxic and EG causes metabolic acidosis." | 1.33 | Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. ( Byer, KJ; Glenton, PA; Khan, SR, 2006) |
| "(1)The total cell number in BALF in pulmonary fibrosis groups was statistically significantly higher than that in NC group (all P<0." | 1.33 | [Kinetics and mechanism in bleomycin-induced murine pulmonary fibrosis model]. ( Gao, ZC; Hu, P, 2006) |
| "Lung inflammation was measured by quantitative differential evaluation of lung lavage cells." | 1.32 | Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. ( Kenyon, NJ; Last, JA; Pinkerton, KE; Temple, L; Ward, R, 2004) |
| "Reduced fibrosis is due to deregulated fibroblast function, as the inflammatory response induced by bleomycin was similar in wild-type and Smad3(-/-) mice." | 1.32 | Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. ( Chen, SJ; DiPietro, LA; Ferreira, AM; Han, G; Lakos, G; Masuda, K; Takagawa, S; Varga, J; Wang, XJ, 2004) |
| "Although no single animal model of systemic sclerosis (SSc) faithfully reproduces all features of the human disease, certain animal models that display some of the features of SSc are potentially useful as they may be helpful in gaining a better understanding of the pathogenesis of SSc as well as developing novel therapeutic interventions." | 1.32 | Animal models of scleroderma. ( Lakos, G; Takagawa, S; Varga, J, 2004) |
| "Treatment with pirfenidone significantly reduced the number of these cells compared with the corresponding BL group." | 1.32 | Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis. ( Abe, K; Fujii, T; Hayashi, T; Ishii, H; Kadota, J; Kakugawa, T; Kohno, S; Miyazaki, M; Mukae, H; Oku, H, 2004) |
| "Pulmonary fibrosis was induced in CCR2-/- and wild-type (CCR2+/+) mice by intratracheal instillation of bleomycin." | 1.32 | C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases. ( Kaikita, K; Kawasuji, M; Kobayashi, H; Kuziel, WA; Okuma, T; Takeya, M; Terasaki, Y, 2004) |
| "Quinapril treatment improved survival markedly (P<0." | 1.31 | Heart failure development in rats with ascending aortic constriction and angiotensin-converting enzyme inhibition. ( Rupp, H; Turcani, M, 2000) |
| "Taurine and niacin treatment significantly reduced the numbers of neutrophils, lymphocytes, and macrophages in the BL + TN group and caused significant reductions in BL-induced increases in the lung hydroxyproline content at 14 and 21 days in the BL + TN group." | 1.31 | Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Silicosis is a crippling fibrotic lung disease induced by inhalation of crystalline silica." | 1.31 | Immunoglobulin responses to experimental silicosis. ( Banks, DE; Huang, SH; Hubbs, AF; Ma, JK; Rojanasakul, Y; Schnabel, PC; Stanley, CF; Vallyathan, V; Weissman, DN, 2001) |
| "The transition from compensated left ventricular hypertrophy (LVH) to heart failure is associated with alterations in the myocardial interstitium." | 1.31 | Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction. ( Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ, 2001) |
| "Pulmonary fibrosis is initiated by migration, adhesion, and proliferation of fibroblasts." | 1.31 | Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis. ( Fukuchi, Y; Ienaga, H; Kon, S; Maeda, K; Maeda, M; Okazaki, T; Takahashi, F; Takahashi, K; Uede, T, 2001) |
| "Liver cirrhosis was induced by CCl(4) inhalation and phenobarbital in Wistar rats." | 1.31 | Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats. ( Castilla-Cortázar, I; García, M; Muguerza, B; Prieto, J; Quiroga, J; Santidrián, S, 2001) |
| "The hydroxyproline/proline ratio was increased by 64% in MI-control and reduced to the sham value in MI-FG041 rats." | 1.31 | Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction. ( Bean, M; Brenner, MC; Buttrick, PM; Geenen, D; Huang, X; Nwogu, JI, 2001) |
| "Bleomycin-induced pulmonary fibrosis was studied in mice rendered LT deficient by knockout of the 5-LO gene (KO) and in wild-type (WT) control mice." | 1.31 | Protection from pulmonary fibrosis in leukotriene-deficient mice. ( Bailie, M; Marshall, T; Moore, BB; Peters-Golden, M; Phan, SH; Toews, GB; Wilke, C, 2002) |
| "Paraquat (PQ) is a herbicide that is very toxic to all living organisms." | 1.31 | Captopril inhibits the pulmonary toxicity of paraquat in rats. ( Alagözlü, H; Candan, F, 2001) |
| "Hydroxyproline levels were significantly lower in the PPC-fed rats than in the rats with pure esophageal burns (p < 0." | 1.31 | Polyunsaturated phosphatidylcholine lowers collagen deposition in a rat model of corrosive esophageal burn. ( Aydin, G; Bitiren, M; Demirbilek, S; Vural, H; Yücesan, S, 2002) |
| " Male F344 rats were intratracheally dosed with AD (6." | 1.31 | Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy. ( Antonini, JM; Hubbs, AF; Reasor, MJ; Roberts, JR; Taylor, MD, 2002) |
| "To elucidate the pathophysiology of pulmonary fibrosis, we investigated the involvement of p38 mitogen-activated protein kinase (MAPK), which is one of the major signal transduction pathways of proinflammatory cytokines, in a murine model of bleomycin-induced lung fibrosis." | 1.31 | A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis. ( Arai, T; Fujiwara, H; Goya, S; Hayashi, S; Kida, H; Matsuoka, H; Mori, M; Morishita, H; Osaki, T; Tachibana, I, 2002) |
| "Colchicine treatment was associated with increased interstitium in WKY with increased passive myocardial stiffness." | 1.30 | Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat. ( Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Hayes, JA; Robinson, KG; Sen, S, 1997) |
| "Pirfenidone (PFD) is a novel anti-fibrotic agent that can prevent and even reverse extracellular matrix accumulation in several organs, as shown by experimental and clinical studies." | 1.30 | Pirfenidone improves renal function and fibrosis in the post-obstructed kidney. ( Fukagawa, M; Hata, S; Kuroda, T; Kurokawa, K; Margolin, SB; Shimizu, T, 1998) |
| "Hydroxyproline (HP) was assayed biochemically, and the amount of HP in the alveolar wall for each rabbit was calculated using the assayed values of HP and the ratio of histologic collagen points in the alveolar wall to those in the lung tissue by a point count method." | 1.29 | Suppressive effect of anti-alpha 1-antichymotrypsin serum on pulmonary fibrosis induced by phorbol myristate acetate in vivo. ( Imakon, Y; Matsubara, H; Nagareda, T; Nishizawa, Y; Noro, A; Shiomi, H; Tanaka, A; Terada, N, 1995) |
| "The hydroxyproline assay was used to determine collagen and elastin content biochemically." | 1.29 | Peripheral vascular alterations during experimental heart failure in the rat. Do they exist? ( Aarts, PJ; Arends, JW; Daemen, MJ; Heeneman, S; Leenders, PJ; Smits, JF, 1995) |
| "Amiodarone is an effective antidysrhythmic agent, restricted in use by the development of pulmonary toxicity." | 1.29 | Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration. ( Brien, JF; Evans, CD; Leeder, RG; Massey, TE, 1994) |
| " Therapeutic regimens are largely based on pharmacodynamic information because of difficulties in obtaining and interpreting pharmacokinetic data." | 1.29 | Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: application to the study of intravenous 14C-labeled 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate. ( Koopmans, SJ; Löwik, CW; Papapoulos, SE; van der Wee-Pals, L, 1994) |
| "This unique animal model of progressive pulmonary fibrosis resembles the final stages of human idiopathic pulmonary fibrosis and should facilitate studying underlying mechanisms and potential therapy of progressive pulmonary fibrosis." | 1.29 | A new model of progressive pulmonary fibrosis in rats. ( Gelzleichter, TR; Last, JA; Pinkerton, KE; Walker, RM; Witschi, H, 1993) |
| "A new murine model of Systemic Sclerosis (SSc) has been developed by breeding the Tsk+/+pa tight skin mouse (TSK) and the autoimmune disease-prone NZB strain to produce an F1 hybrid displaying the connective tissue abnormalities of the TSK parent and the autoimmune abnormalities of the NZB parent." | 1.29 | Immunological characterization of (tight skin/NZB)F1 hybrid mice with connective tissue and autoimmune features resembling human systemic sclerosis. ( Bocchieri, MH; Christner, PJ; Henriksen, PD; Jimenez, SA, 1993) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 1.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "Osteoarthritis was induced in mature beagle bitches by the transection of the cranial cruciate ligament." | 1.29 | Effect of diacetyl rhein on the development of experimental osteoarthritis. A biochemical investigation. ( Carney, SL, 1996) |
| "Tamoxifen citrate is an estrogen agonist/antagonist which protects the skeleton from osteopenia when ovarian hormones are depleted." | 1.28 | Tamoxifen in the rat prevents estrogen-deficiency bone loss elicited with the LHRH agonist buserelin. ( Feng, W; Gold, E; Goulding, A, 1992) |
| "Lung hydroxyproline concentration was characterized as a marker of lung collagen." | 1.28 | Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis. ( Asquith, T; Driscoll, KE; Higgins, J; Maurer, JK; Miller, NS; Poynter, J, 1992) |
| "Hydroxyproline concentration was determined by Stegemann method using the modification of Hurych and Chvapil (2)." | 1.28 | [Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue]. ( Ociepiński, M; Szaflarska-Stojko, E; Zyłka-Włoszczyk, M, 1991) |
| "Osteomyelitis was induced artificially by injecting Staphylococcus aureus culture in the tibiae of young rabbits." | 1.28 | Excretion of urinary hydroxyproline in correlation with severity of induced osteomyelitis in rabbits. ( Abbas, HL, 1991) |
| "Experimental bladder outlet obstruction in cats was produced by surgical placement of a silastic cuff around the urethra." | 1.28 | Short term functional effects of bladder outlet obstruction in the cat. ( Elbadawi, A; Kato, K; Levin, RM; Longhurst, PA; McGuire, EJ; Miller, LF; Radzinski, C; Wein, AJ, 1990) |
| " To determine if lung injury, inflammation, and asbestosis could be inhibited in vivo in a rapid-onset, inhalation model of disease, a novel method of chronic administration of antioxidant enzymes was developed." | 1.28 | Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis. ( Adler, KB; Doherty, J; Hemenway, D; Hill, S; Marsh, JP; Mickey, R; Mossman, BT; Petruska, J; Sesko, A; Shatos, MA, 1990) |
| "Static and dynamic parameters of bone resorption and formation were determined." | 1.28 | Trabecular bone remodeling and bone mineral density in the adult cat during chronic dietary acidification with ammonium chloride. ( Ching, SV; Fettman, MJ; LeCouteur, RA; Norrdin, RW, 1990) |
| "Obstructive lymphedema is a pathologic condition resulting in the accumulation and stagnation of serum proteins in the lymphatics and interstitial spaces." | 1.27 | Protein metabolism and fibrosis in experimental canine obstructive lymphedema. ( Barton, RM; Chen, HC; Coe, SA; Collopy, PA; Knight, KR; McCann, JJ; O'Brien, BM; Vanderkolk, CA, 1987) |
| "Bleomycin (BLM) produces pulmonary fibrosis in mice when given as a single intratracheal injection, a single i." | 1.27 | High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis. ( Harrison, JH; Lazo, JS, 1987) |
| " Dose-response curves for BF could only be made at 76 wk post-irradiation." | 1.27 | Late functional, biochemical and histological changes in the rat lung after fractionated irradiation to the whole thorax. ( Durham, SK; Tan, CH; van Rongen, E, 1987) |
| "Animals were primed for contact hypersensitivity responses by skin painting with trinitrophenol (TNP), but instead of challenging with the antigen on the skin, animals were challenged with a single intratracheally administered dose of the immunizing hapten." | 1.27 | Pulmonary interstitial fibrosis induced in hapten-immune hamsters. ( Fisch, H; Lipscomb, MF; Stein-Streilein, J; Whitney, PL, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (11.00) | 18.7374 |
| 1990's | 85 (13.96) | 18.2507 |
| 2000's | 198 (32.51) | 29.6817 |
| 2010's | 238 (39.08) | 24.3611 |
| 2020's | 21 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Song, S | 1 |
| Fu, Z | 1 |
| Guan, R | 1 |
| Zhao, J | 3 |
| Yang, P | 1 |
| Li, Y | 11 |
| Yin, H | 1 |
| Lai, Y | 1 |
| Gong, G | 1 |
| Zhao, S | 1 |
| Yu, J | 1 |
| Peng, X | 1 |
| He, Y | 2 |
| Luo, Y | 1 |
| Zhong, N | 1 |
| Su, J | 1 |
| Kim, AD | 1 |
| Kim, SE | 1 |
| Leszczynska, A | 1 |
| Kaufmann, B | 1 |
| Reca, A | 1 |
| Kim, DJ | 1 |
| Feldstein, AE | 1 |
| Li, M | 2 |
| Wang, R | 1 |
| Wang, B | 1 |
| Athari, SS | 1 |
| Wang, J | 8 |
| Yang, H | 1 |
| Wang, L | 5 |
| Yang, M | 1 |
| Hu, J | 2 |
| Zhang, E | 1 |
| Peng, L | 1 |
| Piao, C | 1 |
| Zhuang, C | 1 |
| Ko, MK | 1 |
| Hwang, DW | 1 |
| Lee, M | 1 |
| Suzuka, T | 1 |
| Kotani, T | 1 |
| Saito, T | 1 |
| Matsuda, S | 1 |
| Sato, T | 1 |
| Takeuchi, T | 1 |
| Abdullah, A | 2 |
| Çiğdem, Y | 2 |
| Tuğrul, EE | 2 |
| Erhan, A | 2 |
| Zhang, C | 3 |
| Cai, R | 1 |
| Lazerson, A | 1 |
| Delcroix, G | 1 |
| Wangpaichitr, M | 1 |
| Mirsaeidi, M | 1 |
| Griswold, AJ | 1 |
| Schally, AV | 1 |
| Jackson, RM | 1 |
| Atluri, K | 1 |
| Brouillette, MJ | 1 |
| Seol, D | 1 |
| Khorsand, B | 1 |
| Sander, E | 1 |
| Salem, AK | 1 |
| Fredericks, D | 1 |
| Petersen, E | 1 |
| Smith, S | 1 |
| Fowler, TP | 1 |
| Martin, JA | 2 |
| Fan, CF | 1 |
| Zhang, HX | 1 |
| Tang, YH | 1 |
| Xu, HH | 1 |
| Song, D | 1 |
| Buchalski, B | 2 |
| Wood, KD | 1 |
| Challa, A | 1 |
| Fargue, S | 2 |
| Holmes, RP | 2 |
| Lowther, WT | 1 |
| Knight, J | 2 |
| Lu, Y | 2 |
| Zhao, C | 3 |
| Lei, L | 3 |
| Tao, Z | 2 |
| Zheng, L | 1 |
| Wen, J | 1 |
| Li, X | 10 |
| Ye, HL | 1 |
| Zhang, JW | 1 |
| Chen, XZ | 1 |
| Wu, PB | 1 |
| Chen, L | 4 |
| Zhang, G | 4 |
| Alaqeel, M | 1 |
| Grant, MP | 1 |
| Epure, LM | 1 |
| Salem, O | 1 |
| AlShaer, A | 1 |
| Huk, OL | 1 |
| Bergeron, SG | 1 |
| Zukor, DJ | 1 |
| Kc, R | 1 |
| Im, HJ | 1 |
| Anbazhagan, AN | 1 |
| Antoniou, J | 1 |
| Mwale, F | 1 |
| Qu, SJ | 1 |
| Zhao, L | 2 |
| Song, ZZ | 1 |
| Shen, WP | 1 |
| Ju, P | 1 |
| Li, YM | 2 |
| Mao, J | 1 |
| Zhang, H | 1 |
| Wang, X | 12 |
| Gao, J | 7 |
| Tang, J | 1 |
| Zhang, J | 7 |
| Corden, B | 1 |
| Lim, WW | 1 |
| Song, W | 1 |
| Chen, X | 4 |
| Ko, NSJ | 1 |
| Su, L | 1 |
| Tee, NGZ | 1 |
| Adami, E | 1 |
| Schafer, S | 1 |
| Cook, SA | 1 |
| Li, RF | 1 |
| Chen, XY | 1 |
| Xu, Y | 2 |
| Feng, FC | 1 |
| He, HL | 1 |
| Zhou, XM | 3 |
| Nakanishi, Y | 1 |
| Horimasu, Y | 1 |
| Yamaguchi, K | 1 |
| Sakamoto, S | 1 |
| Masuda, T | 1 |
| Nakashima, T | 1 |
| Miyamoto, S | 1 |
| Iwamoto, H | 1 |
| Ohshimo, S | 1 |
| Fujitaka, K | 1 |
| Hamada, H | 1 |
| Hattori, N | 1 |
| Stegemann, A | 1 |
| Raker, V | 1 |
| Del Rey, A | 1 |
| Steinbrink, K | 1 |
| Böhm, M | 1 |
| Daud, E | 1 |
| Ertracht, O | 1 |
| Bandel, N | 1 |
| Moady, G | 1 |
| Shehadeh, M | 1 |
| Reuveni, T | 1 |
| Atar, S | 1 |
| Potnuri, AG | 1 |
| Reddy, KP | 1 |
| Suresh, P | 1 |
| Husain, GM | 1 |
| Kazmi, MH | 1 |
| Harishankar, N | 1 |
| Li, J | 7 |
| Ren, G | 1 |
| Zhang, W | 6 |
| Elhenawy, AA | 1 |
| Ashour, RH | 1 |
| Nabih, N | 1 |
| Shalaby, NM | 1 |
| Megahed, N | 1 |
| Arauz, J | 1 |
| Zarco, N | 1 |
| Hernández-Aquino, E | 1 |
| Galicia-Moreno, M | 1 |
| Favari, L | 1 |
| Segovia, J | 1 |
| Muriel, P | 2 |
| Zhou, J | 2 |
| Jin, J | 1 |
| Zhao, Z | 2 |
| Zhang, L | 3 |
| Wang, Q | 5 |
| Zhang, Q | 1 |
| Xiang, S | 1 |
| Rasooli, R | 1 |
| Pourgholamhosein, F | 1 |
| Kamali, Y | 1 |
| Nabipour, F | 1 |
| Mandegary, A | 1 |
| Bian, H | 1 |
| Yang, Q | 1 |
| Ma, T | 1 |
| Li, W | 4 |
| Duan, J | 1 |
| Wei, G | 1 |
| Wu, X | 1 |
| Mu, F | 1 |
| Lin, R | 1 |
| Wen, A | 1 |
| Xi, M | 1 |
| Chen, XJ | 1 |
| Liu, S | 3 |
| Gao, GZ | 1 |
| Yan, DX | 1 |
| Jiang, WS | 1 |
| Yamada, F | 1 |
| Endo, N | 1 |
| Miyatake, S | 1 |
| Ebisu, G | 1 |
| Hino, K | 1 |
| Shin, SK | 1 |
| Kwon, OS | 1 |
| Lee, JJ | 1 |
| Park, YH | 2 |
| Choi, CS | 1 |
| Jeong, SH | 1 |
| Choi, DJ | 1 |
| Kim, YS | 1 |
| Kim, JH | 3 |
| Xu, K | 1 |
| Yang, XY | 1 |
| Liu, J | 6 |
| Zeng, Q | 1 |
| Wang, FS | 2 |
| Oliva, ME | 1 |
| Creus, A | 1 |
| Ferreira, MR | 1 |
| Chicco, A | 1 |
| Lombardo, YB | 1 |
| Zhang, S | 3 |
| Cui, R | 1 |
| Pawar, HS | 1 |
| Francis, NK | 1 |
| Hota, T | 1 |
| Peter, N | 1 |
| Mitra, A | 1 |
| Hemmati, AA | 2 |
| Larki-Harchegani, A | 1 |
| Shabib, S | 1 |
| Jalali, A | 1 |
| Rezaei, A | 1 |
| Housmand, G | 1 |
| Dhar, A | 1 |
| Sadiq, F | 1 |
| Anstee, QM | 1 |
| Levene, AP | 1 |
| Goldin, RD | 1 |
| Thursz, MR | 1 |
| Feng, S | 1 |
| Karkale, S | 1 |
| Khurana, A | 1 |
| Saifi, MA | 1 |
| Godugu, C | 1 |
| Talla, V | 1 |
| O'Dwyer, DN | 1 |
| Moore, BB | 2 |
| Liu, H | 1 |
| Jiang, Z | 2 |
| Shen, S | 1 |
| Mei, J | 1 |
| Tang, M | 1 |
| Ji, Y | 1 |
| Dai, Z | 1 |
| Sun, S | 2 |
| Ma, X | 1 |
| Yang, Y | 3 |
| Tso, P | 1 |
| Wu, G | 1 |
| Wu, Z | 1 |
| Hao, Y | 1 |
| Ran, Y | 1 |
| Lu, B | 1 |
| Feng, C | 1 |
| Fang, J | 2 |
| Ma, R | 1 |
| Qiao, Z | 1 |
| Dai, X | 1 |
| Xiong, W | 1 |
| Zhou, Q | 2 |
| Hao, J | 2 |
| Li, R | 2 |
| Dai, J | 1 |
| Raish, M | 1 |
| Ahmad, A | 1 |
| Ahmad Ansari, M | 1 |
| Ahad, A | 1 |
| Al-Jenoobi, FI | 1 |
| Al-Mohizea, AM | 1 |
| Khan, A | 2 |
| Ali, N | 1 |
| Hünerwadel, A | 1 |
| Fagagnini, S | 1 |
| Rogler, G | 1 |
| Lutz, C | 1 |
| Jaeger, SU | 1 |
| Mamie, C | 1 |
| Weder, B | 1 |
| Ruiz, PA | 1 |
| Hausmann, M | 1 |
| Sun, L | 2 |
| Mao, M | 1 |
| Yan, Z | 1 |
| Zuo, C | 1 |
| Zhang, X | 3 |
| Cui, D | 1 |
| Zhao, D | 1 |
| Huang, S | 1 |
| Li, PF | 1 |
| He, RH | 1 |
| Shi, SB | 1 |
| Wang, QT | 1 |
| Rao, GT | 1 |
| Yang, B | 1 |
| Shariati, S | 1 |
| Kalantar, H | 1 |
| Pashmforoosh, M | 1 |
| Mansouri, E | 1 |
| Khodayar, MJ | 1 |
| Xu, J | 3 |
| Xu, S | 1 |
| Gao, W | 1 |
| Yu, Z | 1 |
| Zhang, YF | 1 |
| Sun, CC | 1 |
| Tang, CY | 1 |
| Sun, GY | 1 |
| Luo, WJ | 1 |
| Zhou, Y | 2 |
| Guan, CX | 1 |
| Alemzadeh, E | 1 |
| Oryan, A | 2 |
| Mohammadi, AA | 1 |
| Yadav, S | 1 |
| Yuan, CC | 1 |
| Kazmierczak, K | 1 |
| Liang, J | 1 |
| Huang, W | 2 |
| Takeuchi, LM | 1 |
| Kanashiro-Takeuchi, RM | 1 |
| Szczesna-Cordary, D | 1 |
| Shi, Y | 3 |
| Dong, M | 1 |
| Gao, Y | 3 |
| Han, L | 2 |
| Chen, M | 1 |
| Lin, H | 1 |
| Zuo, W | 1 |
| Jin, F | 1 |
| Şen Tanrıkulu, C | 1 |
| Tanrıkulu, Y | 1 |
| Kılınç, F | 1 |
| Bahadır, B | 1 |
| Can, M | 1 |
| Köktürk, F | 1 |
| Kefeli, A | 1 |
| Ren, J | 2 |
| Rudemiller, NP | 1 |
| Griffiths, R | 1 |
| Wen, Y | 1 |
| Lu, X | 3 |
| Privratsky, JR | 1 |
| Gunn, MD | 1 |
| Crowley, SD | 1 |
| Wang, Y | 6 |
| Liang, Z | 1 |
| Feng, M | 1 |
| Zhao, X | 2 |
| Qin, K | 1 |
| Gao, C | 1 |
| Guo, H | 2 |
| Luo, J | 1 |
| Donmez, R | 1 |
| Oren, D | 1 |
| Ozturk, G | 1 |
| Kisaoglu, A | 1 |
| Ozogul, B | 1 |
| Atamanalp, SS | 1 |
| Wang, W | 5 |
| Khan, SR | 6 |
| Marques e Silva, S | 1 |
| Carneiro, FP | 1 |
| Ferreira, VM | 1 |
| Oliveira, PG | 1 |
| Sousa, JB | 1 |
| Lu, J | 2 |
| Zhang, Y | 4 |
| Chen, Y | 8 |
| Gu, Z | 1 |
| Jiang, X | 1 |
| Yao, X | 1 |
| Carleton, SM | 1 |
| Kettle, AD | 1 |
| Melander, J | 1 |
| Phillips, CL | 1 |
| Liu, R | 1 |
| Chen, H | 3 |
| Bai, H | 1 |
| Qin, X | 1 |
| Liang, X | 1 |
| Hai, C | 1 |
| Bhardwaj, P | 1 |
| Rai, DV | 1 |
| Garg, ML | 1 |
| Hara, M | 1 |
| Kono, H | 1 |
| Furuya, S | 1 |
| Hirayama, K | 1 |
| Tsuchiya, M | 1 |
| Fujii, H | 1 |
| Xu, L | 4 |
| Yang, D | 1 |
| Zhu, S | 2 |
| Gu, J | 3 |
| Ding, F | 2 |
| Bian, W | 1 |
| Rong, Z | 1 |
| Shen, C | 1 |
| Collins, BH | 1 |
| Holzknecht, ZE | 1 |
| Lynn, KA | 1 |
| Sempowski, GD | 1 |
| Smith, CC | 1 |
| Parker, W | 1 |
| Rockey, DC | 1 |
| Chen, D | 3 |
| Jiang, T | 1 |
| Feng, Y | 1 |
| Zhou, M | 1 |
| Han, X | 1 |
| Vieira, CP | 3 |
| De Aro, AA | 3 |
| Da Ré Guerra, F | 1 |
| De Oliveira, LP | 1 |
| De Almeida, Mdos S | 2 |
| Pimentel, ER | 4 |
| Spivak, MIa | 1 |
| Lazarenko, LM | 1 |
| Falalieieva, TM | 1 |
| Virchenko, OV | 1 |
| Neporada, KS | 1 |
| Dong, W | 1 |
| Lv, B | 1 |
| Wei, F | 1 |
| Yang, L | 4 |
| Gochuico, BR | 1 |
| Yu, G | 2 |
| Tang, X | 1 |
| Osorio, JC | 1 |
| Fernandez, IE | 1 |
| Risquez, CF | 1 |
| Patel, AS | 1 |
| Wathelet, MG | 1 |
| Goodwin, AJ | 1 |
| Haspel, JA | 1 |
| Ryter, SW | 1 |
| Billings, EM | 1 |
| Kaminski, N | 1 |
| Morse, D | 1 |
| Rosas, IO | 1 |
| Nakagaki, WR | 1 |
| Tomiosso, TC | 1 |
| Camilli, JA | 1 |
| Liang, CZ | 1 |
| Li, H | 3 |
| Tao, YQ | 1 |
| Peng, LH | 1 |
| Gao, JQ | 1 |
| Wu, JJ | 1 |
| Li, FC | 1 |
| Hua, JM | 1 |
| Chen, QX | 1 |
| Murthy, S | 1 |
| Gautam, MK | 1 |
| Goel, S | 1 |
| Purohit, V | 1 |
| Sharma, H | 1 |
| Goel, RK | 1 |
| Tao, YY | 1 |
| Wang, QL | 1 |
| Shen, L | 1 |
| Fu, WW | 1 |
| Liu, CH | 2 |
| Zhang, SH | 1 |
| Wen, KM | 1 |
| Wu, W | 1 |
| Li, WY | 1 |
| Zhao, JN | 1 |
| Lieber, GB | 1 |
| Fernandez, X | 1 |
| Mingo, GG | 1 |
| Jia, Y | 2 |
| Caniga, M | 1 |
| Gil, MA | 1 |
| Keshwani, S | 1 |
| Woodhouse, JD | 1 |
| Cicmil, M | 1 |
| Moy, LY | 1 |
| Kelly, N | 1 |
| Jimenez, J | 1 |
| Crawley, Y | 1 |
| Anthes, JC | 1 |
| Klappenbach, J | 1 |
| Ma, YL | 1 |
| McLeod, RL | 1 |
| Meimandi-Parizi, A | 1 |
| Moshiri, A | 1 |
| Wang, YR | 1 |
| Yang, DY | 1 |
| Zhang, M | 3 |
| Liu, W | 3 |
| Wan, J | 1 |
| Han, JZ | 1 |
| Li, C | 1 |
| Feng, DD | 1 |
| Yue, SJ | 1 |
| Huang, YH | 1 |
| Cheng, QM | 1 |
| Luo, ZQ | 1 |
| Zhang, Z | 4 |
| Jian, X | 1 |
| Madala, SK | 1 |
| Edukulla, R | 1 |
| Schmidt, S | 1 |
| Davidson, C | 1 |
| Ikegami, M | 1 |
| Hardie, WD | 2 |
| Minicucci, MF | 1 |
| Santos, PP | 1 |
| Rafacho, BP | 1 |
| Gonçalves, AF | 1 |
| Ardisson, LP | 1 |
| Batista, DF | 1 |
| Azevedo, PS | 1 |
| Polegato, BF | 1 |
| Okoshi, K | 2 |
| Pereira, EJ | 1 |
| Paiva, SA | 1 |
| Zornoff, LA | 1 |
| Sivalingam, S | 1 |
| Nakada, SY | 3 |
| Sehgal, PD | 1 |
| Crenshaw, TD | 3 |
| Penniston, KL | 3 |
| Liang, C | 1 |
| Yang, W | 1 |
| Redente, EF | 1 |
| Keith, RC | 1 |
| Janssen, W | 1 |
| Henson, PM | 1 |
| Ortiz, LA | 1 |
| Downey, GP | 1 |
| Bratton, DL | 1 |
| Riches, DW | 1 |
| Panda, V | 1 |
| Thakur, T | 1 |
| Son, KH | 1 |
| Jeong, HW | 1 |
| Jung, WW | 1 |
| Kim, HS | 1 |
| Lee, SK | 1 |
| Kim, KT | 1 |
| Ahn, CB | 1 |
| Park, KY | 1 |
| Kim, BM | 1 |
| Lee, SH | 2 |
| El-Agamy, DS | 1 |
| Sharawy, MH | 1 |
| Ammar, EM | 1 |
| Zhang, ZM | 1 |
| Gu, P | 1 |
| Yi, XH | 1 |
| Fang, X | 1 |
| Zeng, Y | 1 |
| Zhang, SX | 1 |
| Zhu, XY | 1 |
| Zhang, YD | 1 |
| Qiu, WZ | 1 |
| Zhou, B | 1 |
| Ding, C | 1 |
| Wu, Y | 2 |
| Chen, J | 7 |
| Wang, G | 1 |
| Gu, G | 1 |
| Galanopoulos, G | 1 |
| Raptis, D | 1 |
| Pramateftakis, MG | 1 |
| Mantzoros, I | 1 |
| Kanellos, I | 1 |
| Lazarides, C | 1 |
| Smith, LR | 1 |
| Barton, ER | 1 |
| Joshi, S | 1 |
| Peck, AB | 1 |
| Liang, Y | 2 |
| Sun, Y | 5 |
| Yan, L | 3 |
| Yu, H | 2 |
| Xiao, H | 1 |
| Sun, Z | 1 |
| Cai, J | 1 |
| Feng, X | 3 |
| Xiong, C | 1 |
| He, J | 2 |
| Egger, C | 1 |
| Gérard, C | 1 |
| Vidotto, N | 1 |
| Accart, N | 1 |
| Cannet, C | 1 |
| Dunbar, A | 1 |
| Tigani, B | 1 |
| Piaia, A | 1 |
| Jarai, G | 1 |
| Jarman, E | 1 |
| Schmid, HA | 1 |
| Beckmann, N | 1 |
| Tung, YT | 1 |
| Tang, TY | 1 |
| Chen, HL | 1 |
| Yang, SH | 1 |
| Chong, KY | 1 |
| Cheng, WT | 2 |
| Chen, CM | 2 |
| Yao, Y | 1 |
| Zhou, C | 1 |
| Chu, D | 1 |
| Geisbush, TR | 1 |
| Rosen, GD | 1 |
| Lachey, J | 1 |
| Mulivor, A | 1 |
| Rutkove, SB | 2 |
| Rhee, CK | 3 |
| Kang, JY | 1 |
| Park, CK | 2 |
| Lee, SY | 3 |
| Kwon, SS | 3 |
| Kim, YK | 3 |
| Yoon, HK | 3 |
| Usategui, A | 1 |
| Criado, G | 1 |
| Del Rey, MJ | 1 |
| Faré, R | 1 |
| Pablos, JL | 1 |
| Shkurupiy, VA | 1 |
| Kim, LB | 1 |
| Potapova, OV | 1 |
| Cherdantseva, LA | 1 |
| Putyatina, AN | 1 |
| Nikonova, IK | 1 |
| Kwon, KD | 1 |
| Choi, MJ | 1 |
| Park, JM | 1 |
| Song, KM | 1 |
| Kwon, MH | 1 |
| Batbold, D | 1 |
| Yin, GN | 1 |
| Kim, WJ | 1 |
| Ryu, JK | 1 |
| Suh, JK | 1 |
| Parra, ER | 1 |
| Pincelli, MS | 1 |
| Teodoro, WR | 1 |
| Velosa, AP | 1 |
| Martins, V | 1 |
| Rangel, MP | 1 |
| Barbas-Filho, JV | 1 |
| Capelozzi, VL | 1 |
| Chaturvedi, AA | 1 |
| Lomme, RM | 2 |
| Hendriks, T | 5 |
| van Goor, H | 4 |
| Peng, SY | 1 |
| Chou, CJ | 1 |
| Cheng, PJ | 1 |
| Ko, IC | 1 |
| Kao, YJ | 1 |
| Chen, YH | 2 |
| Shaw, SW | 1 |
| Wu, SC | 1 |
| Zhang, K | 1 |
| Su, W | 1 |
| Lu, R | 1 |
| Lv, P | 1 |
| Li, LC | 1 |
| Zhao, P | 2 |
| Qi, LW | 1 |
| Li, P | 2 |
| Fei, GH | 1 |
| Mickiewicz, B | 1 |
| Heard, BJ | 1 |
| Chau, JK | 1 |
| Chung, M | 1 |
| Hart, DA | 1 |
| Shrive, NG | 1 |
| Frank, CB | 1 |
| Vogel, HJ | 1 |
| Wong, L | 1 |
| Hutson, PR | 1 |
| Bushman, W | 1 |
| Kim, HG | 1 |
| Kim, JM | 1 |
| Han, JM | 1 |
| Lee, JS | 1 |
| Choi, MK | 2 |
| Lee, DS | 1 |
| Son, CG | 3 |
| Zhong, XN | 2 |
| He, ZY | 2 |
| Sun, XJ | 2 |
| Türkoğlu, A | 1 |
| Gül, M | 1 |
| Yuksel, HK | 1 |
| Alabalik, U | 1 |
| Ülger, BV | 1 |
| Uslukaya, O | 1 |
| Avci, Y | 1 |
| Karaca, G | 1 |
| Xie, G | 1 |
| Moylan, C | 1 |
| Swiderska-Syn, M | 1 |
| Guy, CD | 1 |
| Krüger, L | 1 |
| Machado, MV | 1 |
| Choi, SS | 1 |
| Michelotti, GA | 1 |
| Burkly, LC | 1 |
| Diehl, AM | 2 |
| Song, Q | 1 |
| Sergeev, IN | 1 |
| Gan, Z | 1 |
| Jing, J | 1 |
| Zhu, G | 1 |
| Qin, Y | 1 |
| Teng, G | 1 |
| Guo, J | 2 |
| Koh, RY | 1 |
| Lim, CL | 1 |
| Uhal, BD | 2 |
| Abdullah, M | 1 |
| Vidyadaran, S | 1 |
| Ho, CC | 1 |
| Seow, HF | 1 |
| Wu, JS | 1 |
| Greenman, RL | 1 |
| Bennett, D | 1 |
| Geisbush, T | 1 |
| Li, L | 3 |
| Li, D | 2 |
| Deng, Z | 1 |
| Mo, X | 1 |
| Qi, L | 2 |
| Jebahi, S | 1 |
| Saoudi, M | 1 |
| Farhat, L | 1 |
| Oudadesse, H | 1 |
| Rebai, T | 1 |
| Kabir, A | 1 |
| El Feki, A | 1 |
| Keskes, H | 1 |
| Chilakapati, SR | 1 |
| Serasanambati, M | 1 |
| Vissavajjhala, P | 1 |
| Kanala, JR | 1 |
| Chilakapati, DR | 1 |
| Ohashi, T | 1 |
| Yamamoto, T | 5 |
| Wang, YY | 1 |
| Zhang, CY | 1 |
| Ma, YQ | 1 |
| He, ZX | 1 |
| Zhe, H | 1 |
| Zhou, SF | 1 |
| Gu, WL | 1 |
| Chen, CX | 1 |
| Huang, XY | 2 |
| Gao, JP | 1 |
| He, W | 1 |
| Zhuang, Y | 1 |
| Chen, B | 2 |
| Wang, M | 1 |
| Shao, D | 1 |
| Jiang, H | 1 |
| Ren, S | 1 |
| Ercan, U | 1 |
| Kiraz, A | 1 |
| Çikman, Ö | 1 |
| Türkön, H | 1 |
| Kilinç, N | 1 |
| Otkun, MT | 1 |
| Özkan, ÖF | 1 |
| Kiraz, HA | 1 |
| Karaayvaz, M | 1 |
| Nishimoto, T | 1 |
| Mlakar, L | 1 |
| Takihara, T | 1 |
| Feghali-Bostwick, C | 1 |
| Song, Y | 1 |
| Shichino, S | 1 |
| Abe, J | 1 |
| Ueha, S | 1 |
| Otsuji, M | 1 |
| Tsukui, T | 1 |
| Kosugi-Kanaya, M | 1 |
| Shand, FH | 1 |
| Hashimoto, S | 1 |
| Suzuki, HI | 1 |
| Morikawa, T | 1 |
| Inagaki, Y | 1 |
| Matsushima, K | 1 |
| Kim, SW | 1 |
| Kim, TJ | 2 |
| Cai, Y | 1 |
| Kimura, S | 2 |
| Baba, I | 1 |
| Egi, Y | 1 |
| Suzuki, K | 5 |
| Wang, S | 1 |
| Lu, Z | 1 |
| Xu, W | 2 |
| Xiao, Y | 2 |
| Xia, H | 1 |
| Zhu, L | 2 |
| Chen, R | 3 |
| Yin, X | 1 |
| Feng, L | 1 |
| Yu, M | 2 |
| Lou, J | 1 |
| Guan, Z | 1 |
| Inscho, EW | 1 |
| Liebow, A | 1 |
| Fitzgerald, K | 1 |
| Querbes, W | 1 |
| Todd Lowther, W | 1 |
| Schill, KE | 1 |
| Altenberger, AR | 1 |
| Lowe, J | 1 |
| Periasamy, M | 1 |
| Villamena, FA | 1 |
| Rafael-Fortney, JA | 1 |
| Devor, ST | 1 |
| Piroglu, I | 1 |
| Tulgar, S | 1 |
| Thomas, DT | 1 |
| Cakiroglu, B | 1 |
| Piroglu, MD | 1 |
| Bozkurt, Y | 1 |
| Gergerli, R | 1 |
| Ates, NG | 1 |
| Choe, S | 1 |
| Veliceasa, D | 1 |
| Bond, CW | 1 |
| Harrington, DA | 1 |
| Stupp, SI | 1 |
| McVary, KT | 1 |
| Podlasek, CA | 1 |
| Sozutek, A | 1 |
| Colak, T | 1 |
| Cetinkunar, S | 1 |
| Reyhan, E | 1 |
| Irkorucu, O | 1 |
| Polat, G | 1 |
| Cennet, A | 1 |
| Gündoğdu, RH | 1 |
| Temel, H | 1 |
| Bozkırlı, BO | 1 |
| Ersoy, E | 1 |
| Yazgan, A | 1 |
| Yıldırım, Z | 3 |
| Kimura, K | 1 |
| Zhou, H | 1 |
| Orita, T | 1 |
| Kobayashi, S | 1 |
| Wada, T | 1 |
| Nakamura, Y | 1 |
| Nishida, T | 1 |
| Sonoda, KH | 1 |
| Zhang, YQ | 1 |
| Yang, G | 1 |
| Deng, Y | 1 |
| Rao, J | 1 |
| Liu, X | 1 |
| Lv, L | 3 |
| Liu, F | 2 |
| Liu, D | 1 |
| Du, H | 1 |
| Yang, X | 1 |
| Cui, W | 1 |
| Sui, X | 2 |
| Sakai, S | 1 |
| Iwata, C | 1 |
| Tanaka, HY | 1 |
| Cabral, H | 1 |
| Morishita, Y | 1 |
| Miyazono, K | 1 |
| Kano, MR | 1 |
| Gomes, A | 3 |
| Ghosh, S | 2 |
| Saha, K | 1 |
| Saha, PP | 1 |
| Dasgupta, SC | 1 |
| Lucattelli, M | 1 |
| Fineschi, S | 1 |
| Selvi, E | 1 |
| Garcia Gonzalez, E | 1 |
| Bartalesi, B | 1 |
| De Cunto, G | 1 |
| Lorenzini, S | 1 |
| Galeazzi, M | 1 |
| Lungarella, G | 1 |
| Abuelezz, SA | 1 |
| Hendawy, N | 1 |
| Osman, WM | 1 |
| Sharma, A | 1 |
| Hye Khan, MA | 1 |
| Levick, SP | 1 |
| Lee, KS | 1 |
| Hammock, BD | 1 |
| Imig, JD | 1 |
| Moczydlowska, J | 1 |
| Miltyk, W | 1 |
| Hermanowicz, A | 1 |
| Lebensztejn, DM | 1 |
| Palka, JA | 1 |
| Debek, W | 1 |
| Ozcelik, U | 1 |
| Ekici, Y | 1 |
| Bircan, HY | 1 |
| Aydogan, C | 1 |
| Turkoglu, S | 1 |
| Ozen, O | 1 |
| Moray, G | 2 |
| Haberal, M | 2 |
| Shi, L | 1 |
| Zhao, F | 1 |
| Zhu, F | 2 |
| Yang, F | 1 |
| Yin, L | 1 |
| Li, Q | 1 |
| Qiu, M | 1 |
| Gómez-Roso, M | 1 |
| Montero, MJ | 1 |
| Carrón, R | 1 |
| Sevilla, MA | 1 |
| Nagar, HK | 1 |
| Srivastava, AK | 1 |
| Srivastava, R | 1 |
| Ranawat, MS | 1 |
| Rao, HY | 1 |
| Teng, X | 1 |
| Ren, YY | 1 |
| Lu, YQ | 1 |
| Wu, N | 1 |
| Liu, FF | 1 |
| Wei, L | 2 |
| El-Demerdash, E | 2 |
| Abdel-Sattar, SA | 1 |
| El-Bakly, WM | 1 |
| Mohamed, EA | 1 |
| Kim, YO | 1 |
| Popov, Y | 1 |
| Schuppan, D | 4 |
| Liu, K | 2 |
| Rao, Y | 1 |
| Wu, J | 2 |
| Wu, Q | 2 |
| Cleveland, ZI | 1 |
| Zhou, YM | 1 |
| Akinyi, TG | 1 |
| Dunn, RS | 1 |
| Davidson, CR | 1 |
| Woods, JC | 1 |
| Fukui, A | 1 |
| Ikebe-Ebata, Y | 1 |
| Kondo, H | 2 |
| Saito, S | 1 |
| Aoki, K | 1 |
| Fukunaga, N | 1 |
| Shinohara, T | 1 |
| Masaki, T | 1 |
| Teshima, Y | 1 |
| Takahashi, N | 1 |
| Veneziano, SG | 1 |
| Ramalho, LN | 2 |
| Ramalho, FS | 2 |
| Campos, AD | 1 |
| Rocha, JJ | 1 |
| Feres, O | 2 |
| Franca, A | 1 |
| da Rocha, JJ | 1 |
| Nazari, Z | 1 |
| Samei, M | 1 |
| Weng, D | 2 |
| Tian, L | 1 |
| Tao, S | 1 |
| Wang, F | 1 |
| Teng, L | 1 |
| Cao, J | 1 |
| Ayten, R | 1 |
| Cetinkaya, Z | 1 |
| Girgin, M | 1 |
| Ozercan, I | 1 |
| Ustundag, B | 3 |
| Aygen, E | 1 |
| Watanabe, M | 1 |
| Murata, S | 1 |
| Hashimoto, I | 1 |
| Nakano, Y | 2 |
| Ikeda, O | 1 |
| Aoyagi, Y | 1 |
| Matsuo, R | 1 |
| Fukunaga, K | 1 |
| Yasue, H | 1 |
| Ohkohchi, N | 1 |
| Pereira, RM | 1 |
| dos Santos, RA | 1 |
| Oliveira, EA | 1 |
| Leite, VH | 1 |
| Dias, FL | 1 |
| Rezende, AS | 1 |
| Costa, LP | 1 |
| Barcelos, LS | 1 |
| Teixeira, MM | 1 |
| Simoes e Silva, AC | 1 |
| Aarts, F | 1 |
| Bleichrodt, RP | 4 |
| de Man, B | 1 |
| Lomme, R | 1 |
| Boerman, OC | 1 |
| Sands, MF | 1 |
| Ohtake, PJ | 1 |
| Mahajan, SD | 1 |
| Takyar, SS | 1 |
| Aalinkeel, R | 1 |
| Fang, YV | 1 |
| Blume, JW | 1 |
| Mullan, BA | 1 |
| Sykes, DE | 1 |
| Lachina, S | 1 |
| Knight, PR | 1 |
| Schwartz, SA | 1 |
| Gurung, S | 1 |
| Skalko-Basnet, N | 1 |
| Uludag, M | 2 |
| Citgez, B | 2 |
| Ozkaya, O | 2 |
| Yetkin, G | 2 |
| Ozcan, O | 2 |
| Polat, N | 2 |
| Isgor, A | 2 |
| Sheng, R | 1 |
| Gu, ZL | 1 |
| Xie, ML | 1 |
| Zhou, WX | 1 |
| Guo, CY | 2 |
| Kuramoto, E | 1 |
| Nishiuma, T | 1 |
| Kobayashi, K | 1 |
| Yamamoto, M | 2 |
| Kono, Y | 1 |
| Funada, Y | 1 |
| Kotani, Y | 1 |
| Sisson, TH | 2 |
| Simon, RH | 2 |
| Nishimura, Y | 1 |
| Sun, T | 1 |
| Shen, LH | 1 |
| Li, HW | 1 |
| Li, ZZ | 1 |
| Tang, CS | 2 |
| Li, FY | 1 |
| Cheng, NS | 1 |
| Cheng, JQ | 1 |
| Mao, H | 1 |
| Jiang, LS | 1 |
| Li, N | 1 |
| He, S | 1 |
| Türkyilmaz, Z | 2 |
| Sönmez, K | 2 |
| Karabulut, R | 2 |
| Gülbahar, O | 1 |
| Poyraz, A | 2 |
| Sancak, B | 1 |
| Başaklar, AC | 2 |
| Gao, S | 1 |
| Long, CL | 1 |
| Wang, RH | 1 |
| Wang, H | 2 |
| Gonzalez, ET | 1 |
| Iyer, SS | 1 |
| Mac, V | 1 |
| Mora, AL | 2 |
| Sutliff, RL | 1 |
| Reed, A | 1 |
| Brigham, KL | 1 |
| Kelly, P | 1 |
| Rojas, M | 2 |
| Bennett, RG | 1 |
| Heimann, DG | 1 |
| Tuma, DJ | 1 |
| Yurtçu, M | 1 |
| Arbag, H | 1 |
| Cağlayan, O | 1 |
| Abasiyanik, A | 1 |
| Oz, M | 1 |
| Du, S | 1 |
| Zhang, R | 1 |
| Cui, Y | 2 |
| Yang, J | 3 |
| Wei, Z | 1 |
| Yao, Z | 1 |
| Wiessner, JH | 2 |
| Garrett, MR | 2 |
| Roman, RJ | 1 |
| Mandel, NS | 2 |
| Kassira, N | 1 |
| Glassberg, MK | 1 |
| Jones, C | 1 |
| Pincus, DJ | 1 |
| Elliot, SJ | 1 |
| Fritz, JR | 1 |
| Karl, M | 1 |
| Thaller, S | 1 |
| Robb, WB | 1 |
| Condron, C | 1 |
| Moriarty, M | 1 |
| Walsh, TN | 1 |
| Bouchier-Hayes, DJ | 1 |
| Huang, MM | 1 |
| He, CC | 1 |
| Li, JX | 2 |
| Oh, SW | 1 |
| Kim, DH | 1 |
| Ha, JR | 1 |
| Kim, DY | 1 |
| Ou, XM | 1 |
| Wen, FQ | 1 |
| Feng, YL | 1 |
| Wang, T | 1 |
| Wang, K | 1 |
| Liu, DS | 1 |
| Geng, J | 1 |
| Kang, W | 1 |
| Zhiming, GE | 1 |
| Ersoz, N | 2 |
| Ozler, M | 2 |
| Altinel, O | 1 |
| Sadir, S | 2 |
| Ozerhan, IH | 2 |
| Uysal, B | 1 |
| Topal, T | 2 |
| Guven, A | 1 |
| Korkmaz, A | 3 |
| Wu, YH | 2 |
| Zhang, XM | 1 |
| Hu, MH | 1 |
| Wu, XM | 1 |
| Zhao, Y | 1 |
| Fujita, T | 1 |
| Pan, JB | 1 |
| Hou, YH | 1 |
| Zhang, GJ | 1 |
| Fujibayashi, T | 1 |
| Hashimoto, N | 1 |
| Jijiwa, M | 1 |
| Hasegawa, Y | 1 |
| Kojima, T | 1 |
| Ishiguro, N | 1 |
| French, CJ | 1 |
| Zaman, AK | 1 |
| Sobel, BE | 1 |
| Shi, B | 1 |
| Li, G | 2 |
| Wang, P | 1 |
| Yin, W | 1 |
| Sun, G | 1 |
| Dong, MX | 1 |
| Zhang, YB | 1 |
| Li, CC | 1 |
| Geng, YT | 1 |
| Zhou, L | 1 |
| Li, XY | 1 |
| Liu, JC | 1 |
| Niu, YC | 1 |
| Remund, K | 1 |
| Rechsteiner, T | 1 |
| Guo, Z | 2 |
| Hofer, M | 1 |
| Boehler, A | 1 |
| Kim, HK | 1 |
| Yang, TH | 1 |
| Cho, HY | 1 |
| Qiao, J | 1 |
| Bi, J | 1 |
| Deng, G | 1 |
| He, G | 1 |
| Luan, Z | 1 |
| Lv, N | 1 |
| Xu, T | 1 |
| Guo, XX | 1 |
| Zhou, JL | 1 |
| Xu, Q | 2 |
| Liang, YJ | 1 |
| Weng, J | 1 |
| Shi, XL | 1 |
| Wu, XR | 1 |
| Shi, SS | 1 |
| Guo, WD | 1 |
| Jeon, BJ | 1 |
| Ahn, J | 1 |
| Kwak, HS | 1 |
| Kaplon, DM | 1 |
| Darriet, C | 1 |
| Komai, M | 2 |
| Tanaka, H | 2 |
| Nagao, K | 2 |
| Ishizaki, M | 2 |
| Kajiwara, D | 2 |
| Miura, T | 1 |
| Ohashi, H | 1 |
| Haba, T | 1 |
| Kawakami, K | 1 |
| Sawa, E | 1 |
| Yoshie, O | 1 |
| Inagaki, N | 1 |
| Nagai, H | 2 |
| Baoyong, L | 1 |
| Jian, Z | 1 |
| Denglong, C | 1 |
| Min, L | 1 |
| Liu, JY | 1 |
| Fang, BW | 2 |
| Abdelhalim, MA | 1 |
| Siddiqi, NJ | 1 |
| Alhomida, AS | 1 |
| Al-Ayed, MS | 1 |
| Zhu, Y | 1 |
| Liu, Y | 2 |
| Zhou, W | 1 |
| Xiang, R | 1 |
| Jiang, L | 2 |
| Huang, K | 1 |
| Ramsgaard, L | 1 |
| Englert, JM | 2 |
| Tobolewski, J | 1 |
| Tomai, L | 1 |
| Fattman, CL | 2 |
| Leme, AS | 1 |
| Kaynar, AM | 1 |
| Shapiro, SD | 2 |
| Enghild, JJ | 2 |
| Oury, TD | 3 |
| Yang, FR | 1 |
| Lou, JS | 1 |
| Shin, JW | 2 |
| Wang, JH | 2 |
| Kang, JK | 1 |
| Aksoy, B | 1 |
| Atakan, N | 1 |
| Aksoy, HM | 1 |
| Tezel, GG | 1 |
| Renda, N | 5 |
| Ozkara, HA | 1 |
| Onder, E | 1 |
| Adamcová, M | 1 |
| Potáčová, A | 1 |
| Popelová, O | 1 |
| Štěrba, M | 1 |
| Mazurová, Y | 1 |
| Aupperle, H | 1 |
| Geršl, V | 1 |
| Aktunc, E | 1 |
| Ozacmak, VH | 1 |
| Ozacmak, HS | 1 |
| Barut, F | 1 |
| Buyukates, M | 1 |
| Kandemir, O | 1 |
| Demircan, N | 1 |
| Nishibayashi, S | 1 |
| Hattori, K | 1 |
| Hirano, T | 1 |
| Uehara, K | 1 |
| Aihara, M | 1 |
| Yamada, Y | 1 |
| Muraguchi, M | 1 |
| Iwata, F | 1 |
| Takiguchi, Y | 1 |
| Matsui, K | 1 |
| Ueda, H | 1 |
| Terada, M | 1 |
| Azuma, N | 1 |
| Okamura, H | 1 |
| Sano, H | 1 |
| Shimbori, C | 1 |
| Shiota, N | 1 |
| Okunishi, H | 1 |
| Hessien, MH | 1 |
| El-Sharkawi, IM | 1 |
| El-Barbary, AA | 1 |
| El-Beltagy, DM | 1 |
| Snyder, N | 1 |
| McLaren, MC | 1 |
| McMartin, KE | 1 |
| Dai, S | 2 |
| Jiang, B | 2 |
| Yu, T | 2 |
| Shi, X | 1 |
| Kim, JW | 1 |
| Kim, YH | 1 |
| Kim, SC | 1 |
| Kim, KH | 1 |
| Terashima, H | 1 |
| Kato, M | 1 |
| Yasumo, H | 1 |
| Tsuchida, H | 1 |
| Mizuno, M | 1 |
| Sada, T | 1 |
| Sindhu, ER | 1 |
| Firdous, AP | 1 |
| Preethi, KC | 1 |
| Kuttan, R | 1 |
| Glenton, PA | 3 |
| Pantelis, D | 1 |
| Beissel, A | 1 |
| Kahl, P | 1 |
| Wehner, S | 1 |
| Vilz, TO | 1 |
| Kalff, JC | 1 |
| Ceylan, H | 1 |
| Yapici, S | 1 |
| Tutar, E | 1 |
| Ceylan, NO | 1 |
| Tarakçıoğlu, M | 1 |
| Demiryurek, AT | 1 |
| Seferos, N | 1 |
| Kotsiou, A | 1 |
| Petsaros, S | 1 |
| Rallis, G | 1 |
| Tesseromatis, C | 1 |
| Ooi, CY | 1 |
| Wang, Z | 1 |
| Tabima, DM | 1 |
| Eickhoff, JC | 1 |
| Chesler, NC | 1 |
| Shen, J | 3 |
| Zhong, Z | 1 |
| Wen, H | 1 |
| Luo, Q | 1 |
| Wei, W | 1 |
| Ohbayashi, M | 1 |
| Suzuki, M | 1 |
| Yashiro, Y | 1 |
| Fukuwaka, S | 1 |
| Yasuda, M | 1 |
| Kohyama, N | 1 |
| Kobayashi, Y | 1 |
| Gu, K | 1 |
| Zhao, JD | 1 |
| Ren, ZG | 1 |
| Ma, NY | 1 |
| Lai, ST | 1 |
| Jiang, GL | 1 |
| Hou, J | 2 |
| Tian, J | 1 |
| Jiang, W | 1 |
| Fu, F | 1 |
| Zeki, AA | 1 |
| Bratt, JM | 1 |
| Rabowsky, M | 1 |
| Last, JA | 4 |
| Kenyon, NJ | 2 |
| Hung, LY | 1 |
| Wille, DF | 1 |
| Garlich, MW | 1 |
| Baltgalvis, KA | 1 |
| Call, JA | 1 |
| Dorsey, LL | 1 |
| Lowe, DA | 1 |
| Mannheim, D | 1 |
| Herrmann, J | 1 |
| Bonetti, PO | 1 |
| Lavi, R | 1 |
| Lerman, LO | 1 |
| Lerman, A | 1 |
| Hakim, CH | 3 |
| Grange, RW | 1 |
| Duan, D | 3 |
| Liu, HP | 1 |
| Chen, HY | 1 |
| Tsai, FJ | 1 |
| Chang, CH | 1 |
| Lee, YJ | 1 |
| Lin, WY | 1 |
| Chen, WC | 1 |
| Sanwal, R | 1 |
| Chaudhary, AK | 1 |
| Kliment, CR | 1 |
| Crum, LP | 1 |
| Tian, XP | 1 |
| Yin, YY | 1 |
| Trebicka, J | 1 |
| Racz, I | 1 |
| Siegmund, SV | 1 |
| Cara, E | 1 |
| Granzow, M | 1 |
| Schierwagen, R | 1 |
| Klein, S | 1 |
| Wojtalla, A | 1 |
| Hennenberg, M | 1 |
| Huss, S | 1 |
| Fischer, HP | 1 |
| Heller, J | 1 |
| Zimmer, A | 1 |
| Sauerbruch, T | 1 |
| Courey, AJ | 1 |
| Horowitz, JC | 1 |
| Kim, KK | 1 |
| Koh, TJ | 1 |
| Novak, ML | 1 |
| Subbotina, N | 1 |
| Warnock, M | 1 |
| Xue, B | 2 |
| Cunningham, AK | 1 |
| Lin, Y | 1 |
| Goldklang, MP | 1 |
| Lawrence, DA | 1 |
| El-Lakkany, NM | 1 |
| El-Maadawy, W | 1 |
| Ain-Shoka, A | 1 |
| Badawy, A | 1 |
| Hammam, O | 1 |
| Ebeid, F | 1 |
| Öter, Ş | 1 |
| Shailajan, S | 1 |
| Menon, S | 1 |
| Pednekar, S | 1 |
| Singh, A | 1 |
| Potu, BK | 1 |
| Nampurath, GK | 1 |
| Rao, MS | 1 |
| Bhat, KM | 1 |
| Patel, SR | 1 |
| Iwicki, L | 1 |
| Saeed, I | 1 |
| Jiang, F | 1 |
| Liao, Z | 1 |
| Hu, LH | 1 |
| Du, YQ | 1 |
| Man, XH | 1 |
| Gu, JJ | 1 |
| Gong, YF | 1 |
| Li, ZS | 1 |
| Milton, PL | 1 |
| Dickinson, H | 1 |
| Jenkin, G | 1 |
| Lim, R | 1 |
| Damazo, AS | 1 |
| Sampaio, AL | 1 |
| Nakata, CM | 1 |
| Flower, RJ | 1 |
| Perretti, M | 1 |
| Oliani, SM | 1 |
| Kantah, MK | 1 |
| Kobayashi, R | 1 |
| Sollano, J | 1 |
| Naito, Y | 1 |
| Solimene, U | 1 |
| Jains, S | 1 |
| Catanzaro, R | 1 |
| Minelli, E | 1 |
| Polimeni, A | 1 |
| Marotta, F | 1 |
| Murti, K | 1 |
| Kumar, U | 1 |
| Panchal, M | 1 |
| Xue, J | 1 |
| Xie, M | 1 |
| Knight, V | 1 |
| Tchongue, J | 1 |
| Lourensz, D | 1 |
| Tipping, P | 1 |
| Sievert, W | 1 |
| de Mello, GC | 1 |
| Antunes, E | 1 |
| Akkol, EK | 2 |
| Süntar, I | 2 |
| Erdoğan, TF | 1 |
| Keleş, H | 2 |
| Gonenç, TM | 1 |
| Kıvçak, B | 1 |
| Tumen, I | 1 |
| Ustün, O | 1 |
| Wang, D | 2 |
| Hu, H | 2 |
| Yin, B | 1 |
| Lv, G | 1 |
| Ozgen, M | 1 |
| Koca, SS | 2 |
| Dagli, AF | 1 |
| Gundogdu, B | 1 |
| Isik, A | 2 |
| Paulis, L | 1 |
| Becker, ST | 1 |
| Lucht, K | 1 |
| Schwengel, K | 1 |
| Slavic, S | 1 |
| Kaschina, E | 1 |
| Thöne-Reineke, C | 1 |
| Dahlöf, B | 1 |
| Baulmann, J | 1 |
| Unger, T | 1 |
| Steckelings, UM | 1 |
| Yengo, CM | 1 |
| Zimmerman, SD | 1 |
| McCormick, RJ | 1 |
| Thomas, DP | 1 |
| Dong, Z | 2 |
| Tai, W | 1 |
| Zhang, T | 1 |
| Chai, Y | 1 |
| Zhong, H | 1 |
| Zou, H | 1 |
| Gu, YP | 1 |
| Yuan, BP | 1 |
| Guo, W | 1 |
| Wei, HC | 1 |
| Lv, R | 1 |
| Hwang, SY | 1 |
| Zambelli, V | 1 |
| Di Grigoli, G | 1 |
| Scanziani, M | 1 |
| Valtorta, S | 1 |
| Amigoni, M | 1 |
| Belloli, S | 1 |
| Messa, C | 1 |
| Pesenti, A | 1 |
| Fazio, F | 1 |
| Bellani, G | 1 |
| Moresco, RM | 1 |
| Xiang, D | 1 |
| Qian, L | 1 |
| Wu, M | 1 |
| Yu, Y | 3 |
| Han, W | 2 |
| Onur, E | 1 |
| Akalin, B | 1 |
| Memisoglu, K | 1 |
| Karip, AB | 1 |
| Aydin, MT | 1 |
| Altun, H | 1 |
| Ekci, B | 1 |
| Alam, MA | 1 |
| Sarkar, SK | 1 |
| Silveira, PC | 1 |
| da Silva, LA | 1 |
| Pinho, CA | 1 |
| De Souza, PS | 1 |
| Ronsani, MM | 1 |
| Scheffer, Dda L | 1 |
| Pinho, RA | 1 |
| Jin, Y | 2 |
| Ratnam, K | 1 |
| Chuang, PY | 1 |
| Fan, Y | 1 |
| Zhong, Y | 1 |
| Dai, Y | 1 |
| Mazloom, AR | 1 |
| Chen, EY | 1 |
| D'Agati, V | 1 |
| Xiong, H | 1 |
| Ross, MJ | 1 |
| Chen, N | 1 |
| Ma'ayan, A | 1 |
| He, JC | 1 |
| Hayashi, S | 2 |
| Ikeda, M | 1 |
| Kitamura, Y | 1 |
| Hamasaki, Y | 1 |
| Hatamochi, A | 1 |
| Liu, XY | 1 |
| Shen, W | 1 |
| Yang, K | 1 |
| Qiu, X | 2 |
| Lv, T | 1 |
| Xia, Z | 2 |
| Polasek, M | 1 |
| Fuchs, BC | 1 |
| Uppal, R | 1 |
| Schühle, DT | 1 |
| Alford, JK | 1 |
| Loving, GS | 1 |
| Yamada, S | 1 |
| Lauwers, GY | 1 |
| Guimaraes, AR | 1 |
| Tanabe, KK | 1 |
| Caravan, P | 1 |
| Cai, X | 1 |
| Pan, J | 1 |
| Su, Y | 1 |
| Hou, X | 1 |
| He, H | 1 |
| Rao, P | 1 |
| Maulik, SK | 1 |
| Prabhakar, P | 1 |
| Dinda, AK | 1 |
| Seth, S | 1 |
| Xu, X | 1 |
| Pang, J | 1 |
| Gao, X | 1 |
| Xu, RK | 1 |
| Hao, W | 1 |
| Cao, JM | 1 |
| Chen, C | 1 |
| Ji, S | 1 |
| Xia, T | 1 |
| Pan, B | 1 |
| Xiao, S | 1 |
| Weingärtner, S | 1 |
| Zerr, P | 1 |
| Tomcik, M | 1 |
| Palumbo-Zerr, K | 1 |
| Distler, A | 1 |
| Dees, C | 1 |
| Beyer, C | 1 |
| Shankar, SL | 1 |
| Cedzik, D | 1 |
| Schafer, PH | 1 |
| Distler, O | 1 |
| Schett, G | 1 |
| Distler, JH | 1 |
| Teke, Z | 3 |
| Bostanci, EB | 1 |
| Yenisey, C | 5 |
| Kelten, EC | 1 |
| Sacar, S | 2 |
| Simsek, NG | 1 |
| Duzcan, SE | 1 |
| Akoglu, M | 1 |
| Hu, R | 1 |
| Fu, XC | 1 |
| Shen, LM | 1 |
| Bai, HB | 1 |
| Koczor, CA | 1 |
| Torres, RA | 1 |
| Fields, E | 1 |
| Qin, Q | 1 |
| Park, J | 1 |
| Ludaway, T | 1 |
| Russ, R | 1 |
| Lewis, W | 1 |
| Guerra, Fda R | 1 |
| Almeida, MS | 1 |
| Oliveira, LP | 1 |
| Faxuan, W | 1 |
| Qin, Z | 1 |
| Dinglun, Z | 1 |
| Xiaohui, R | 1 |
| Liqiang, Z | 1 |
| Yajia, L | 1 |
| Ivanova, V | 1 |
| Garbuzenko, OB | 1 |
| Reuhl, KR | 1 |
| Reimer, DC | 1 |
| Pozharov, VP | 1 |
| Minko, T | 1 |
| Liu, C | 2 |
| Yang, Z | 1 |
| Lv, Z | 1 |
| Pan, Q | 1 |
| Lu, L | 1 |
| London, L | 1 |
| Majeski, EI | 1 |
| Altman-Hamamdzic, S | 1 |
| Enockson, C | 1 |
| Paintlia, MK | 1 |
| Harley, RA | 1 |
| London, SD | 1 |
| Fleck, M | 1 |
| Appenroth, D | 3 |
| Malich, A | 1 |
| Stein, G | 2 |
| Fleck, C | 3 |
| Yasukawa, T | 1 |
| Kimura, H | 1 |
| Tabata, Y | 1 |
| Miyamoto, H | 1 |
| Honda, Y | 1 |
| Ogura, Y | 1 |
| Giri, SN | 6 |
| Biring, I | 1 |
| Nguyen, T | 1 |
| Hyde, DM | 4 |
| Wright, JL | 1 |
| Farmer, SG | 1 |
| Churg, A | 1 |
| Cittadini, A | 1 |
| Casaburi, C | 1 |
| Monti, MG | 1 |
| Di Gianni, A | 1 |
| Serpico, R | 1 |
| Scherillo, G | 1 |
| Saldamarco, L | 1 |
| Vanasia, M | 1 |
| Saccà, L | 1 |
| Joseph, J | 1 |
| Washington, A | 1 |
| Joseph, L | 1 |
| Koehler, L | 1 |
| Fink, LM | 1 |
| Hauer-Jensen, M | 1 |
| Kennedy, RH | 1 |
| Değim, Z | 1 |
| Celebi, N | 1 |
| Sayan, H | 1 |
| Babül, A | 1 |
| Erdoğan, D | 1 |
| Take, G | 1 |
| Cui, S | 1 |
| Azuma, A | 1 |
| Takahashi, S | 2 |
| Usuki, J | 1 |
| Matsuda, K | 2 |
| Aoyama, A | 1 |
| Kudoh, S | 1 |
| Brewer, GJ | 1 |
| Ullenbruch, MR | 1 |
| Dick, R | 1 |
| Olivarez, L | 1 |
| Phan, SH | 2 |
| Serrano-Mollar, A | 1 |
| Closa, D | 1 |
| Prats, N | 1 |
| Blesa, S | 1 |
| Martinez-Losa, M | 1 |
| Cortijo, J | 1 |
| Estrela, JM | 1 |
| Morcillo, EJ | 1 |
| Bulbena, O | 1 |
| Corbel, M | 1 |
| Caulet-Maugendre, S | 1 |
| Germain, N | 1 |
| Lagente, V | 1 |
| Boichot, E | 1 |
| Card, JW | 1 |
| Racz, WJ | 1 |
| Brien, JF | 3 |
| Margolin, SB | 2 |
| Massey, TE | 3 |
| Oh, WY | 1 |
| Pyo, S | 1 |
| Lee, KR | 1 |
| Lee, BK | 1 |
| Shin, DH | 1 |
| Cho, SI | 1 |
| Lee, SM | 1 |
| Tian, B | 1 |
| Kleidon, J | 1 |
| Henke, C | 1 |
| Beutinger, R | 1 |
| Lupp, A | 2 |
| Ruiz, V | 1 |
| Ordóñez, RM | 1 |
| Berumen, J | 1 |
| Ramírez, R | 1 |
| Uhal, B | 1 |
| Becerril, C | 1 |
| Pardo, A | 1 |
| Selman, M | 1 |
| Deheza, R | 1 |
| Goto, A | 1 |
| Tsukamoto, I | 2 |
| Chang, LY | 1 |
| Termin, TA | 1 |
| Petersen, L | 1 |
| Ribeiro, HB | 1 |
| Cicogna, AC | 2 |
| Bregagnollo, EA | 1 |
| Rodrigues, MA | 1 |
| Padovani, CR | 1 |
| Aragon, FF | 1 |
| Jamas, E | 1 |
| Okoshi, MP | 1 |
| Takatsu, K | 1 |
| Delespesse, G | 1 |
| Itter, G | 1 |
| Jung, W | 1 |
| Juretschke, P | 1 |
| Schoelkens, BA | 1 |
| Linz, W | 1 |
| Bruck, R | 1 |
| Schey, R | 1 |
| Aeed, H | 1 |
| Hochman, A | 1 |
| Genina, O | 1 |
| Pines, M | 1 |
| Birch Nielsen, C | 1 |
| Krag, S | 1 |
| ØSterby, R | 1 |
| Flyvbjerg, A | 1 |
| Nyengaard, J | 1 |
| Forman, A | 1 |
| Wogensen, L | 1 |
| Vázquez-Gil, MJ | 1 |
| Mesonero, MJ | 1 |
| Flores, O | 1 |
| Criado, M | 1 |
| Hidalgo, F | 1 |
| Arévalo, MA | 1 |
| Sánchez-Rodríguez, A | 1 |
| Tuñón, MJ | 1 |
| López-Novoa, JM | 1 |
| Esteller, A | 1 |
| Chen, YJ | 1 |
| Wang, CJ | 1 |
| Yang, KD | 1 |
| Kuo, YR | 1 |
| Huang, HC | 1 |
| Huang, YT | 1 |
| Sun, YC | 1 |
| Yagmurlu, A | 1 |
| Aksu, B | 1 |
| Bingol-Kologlu, M | 2 |
| Altinok, G | 1 |
| Fitoz, S | 1 |
| Gokcora, IH | 1 |
| Dindar, H | 1 |
| Ward, R | 1 |
| Temple, L | 1 |
| Pinkerton, KE | 2 |
| Lakos, G | 2 |
| Takagawa, S | 4 |
| Chen, SJ | 1 |
| Ferreira, AM | 1 |
| Han, G | 1 |
| Masuda, K | 1 |
| Wang, XJ | 1 |
| DiPietro, LA | 1 |
| Varga, J | 2 |
| Kakugawa, T | 1 |
| Mukae, H | 1 |
| Hayashi, T | 1 |
| Ishii, H | 1 |
| Abe, K | 1 |
| Fujii, T | 1 |
| Oku, H | 1 |
| Miyazaki, M | 1 |
| Kadota, J | 1 |
| Kohno, S | 2 |
| Jiang, ZH | 1 |
| Cui, HY | 1 |
| Liu, P | 1 |
| Xu, LM | 1 |
| Hu, YY | 1 |
| Yuan, JL | 1 |
| Li, FH | 1 |
| Hagiyama, M | 1 |
| Arata, J | 1 |
| Tanioku, K | 1 |
| Okuma, T | 1 |
| Terasaki, Y | 1 |
| Kaikita, K | 1 |
| Kobayashi, H | 1 |
| Kuziel, WA | 1 |
| Kawasuji, M | 1 |
| Takeya, M | 1 |
| Dong, J | 1 |
| Wu, YW | 1 |
| Chen, KD | 1 |
| Lin, WC | 2 |
| Demirtola, A | 1 |
| Gülen, S | 1 |
| Dinçer, S | 1 |
| Kale, N | 1 |
| Yoshiji, H | 1 |
| Kuriyama, S | 1 |
| Noguchi, R | 1 |
| Yoshii, J | 1 |
| Ikenaka, Y | 1 |
| Yanase, K | 1 |
| Namisaki, T | 1 |
| Kitade, M | 1 |
| Yamazaki, M | 1 |
| Tsujinoue, H | 1 |
| Fukui, H | 1 |
| Ayata, A | 1 |
| Mollaoglu, H | 1 |
| Yilmaz, HR | 1 |
| Akturk, O | 1 |
| Ozguner, F | 1 |
| Altuntas, I | 1 |
| de Hingh, IH | 1 |
| de Man, BM | 1 |
| Müller, V | 1 |
| Brummer, D | 1 |
| Erhardt, W | 1 |
| Henke, J | 1 |
| Kissler, H | 1 |
| Bauer, M | 1 |
| Amann, K | 1 |
| Ott, R | 1 |
| Hohenberger, W | 1 |
| Qi, YF | 1 |
| Geng, B | 1 |
| Pan, CS | 1 |
| Chang, JK | 1 |
| Di Vinicius, I | 1 |
| Baptista, AP | 1 |
| Barbosa, AA | 2 |
| Andrade, ZA | 3 |
| Chou, HC | 1 |
| Hsu, HH | 1 |
| Wang, LF | 1 |
| Walters, DM | 1 |
| Antao-Menezes, A | 1 |
| Ingram, JL | 1 |
| Rice, AB | 1 |
| Nyska, A | 1 |
| Tani, Y | 1 |
| Kleeberger, SR | 1 |
| Bonner, JC | 1 |
| Kim, HY | 1 |
| Kim, S | 2 |
| Chung, JH | 1 |
| Park, WS | 1 |
| Chung, DH | 1 |
| Lawson, WE | 1 |
| Polosukhin, VV | 1 |
| Stathopoulos, GT | 1 |
| Zoia, O | 1 |
| Lane, KB | 1 |
| Li, B | 1 |
| Donnelly, EF | 1 |
| Holburn, GE | 1 |
| Lewis, KG | 1 |
| Collins, RD | 1 |
| Hull, WM | 1 |
| Glasser, SW | 1 |
| Whitsett, JA | 1 |
| Blackwell, TS | 1 |
| Zhao, HF | 1 |
| Ito, T | 1 |
| Gibo, J | 1 |
| Kawabe, K | 1 |
| Oono, T | 1 |
| Kaku, T | 1 |
| Arita, Y | 1 |
| Zhao, QW | 1 |
| Usui, M | 1 |
| Egashira, K | 1 |
| Nawata, H | 1 |
| Kotuk, M | 2 |
| Erdogan, H | 2 |
| Iraz, M | 2 |
| Yagmurca, M | 2 |
| Kuku, I | 1 |
| Fadillioglu, E | 2 |
| Huang, SY | 1 |
| Song, LW | 1 |
| Liu, T | 1 |
| Wang, QM | 1 |
| Endo, H | 1 |
| Hashimoto, A | 1 |
| Hayashi, I | 1 |
| Murakami, Y | 1 |
| Kitasato, H | 1 |
| Kojima, F | 1 |
| Kawai, S | 1 |
| Naycı, A | 1 |
| Çömelekoğlu, Ü | 1 |
| Çıngı, E | 1 |
| Taşkınlar, H | 1 |
| Avlan, D | 1 |
| Aksöyek, S | 1 |
| Mukherjee, M | 1 |
| Das, AS | 1 |
| Das, D | 1 |
| Mukherjee, S | 1 |
| Mitra, S | 1 |
| Mitra, C | 1 |
| Johnson, LB | 1 |
| Adawi, D | 1 |
| Agren, MS | 1 |
| Jorgensen, LN | 1 |
| Wittgren, L | 1 |
| Mattsson, S | 1 |
| Blomquist, P | 1 |
| Gottrup, F | 1 |
| Jeppsson, B | 1 |
| Kilic, T | 1 |
| Ermis, H | 1 |
| Yukselen, V | 2 |
| Vardar, E | 2 |
| Yukselen, O | 1 |
| Karaoglu, AO | 1 |
| Ozutemiz, O | 2 |
| Deyhim, F | 1 |
| Garica, K | 1 |
| Lopez, E | 1 |
| Gonzalez, J | 1 |
| Ino, S | 1 |
| Garcia, M | 2 |
| Patil, BS | 1 |
| Gosselin, LE | 1 |
| Williams, JE | 1 |
| Yndestad, A | 1 |
| Vinge, LE | 1 |
| Bjørnerheim, R | 1 |
| Ueland, T | 1 |
| Wang, JE | 1 |
| Frøland, SS | 1 |
| Attramadal, H | 1 |
| Aukrust, P | 1 |
| Oie, E | 1 |
| Gorgulu, S | 1 |
| Yagci, G | 1 |
| Kaymakcioglu, N | 1 |
| Ozkara, M | 1 |
| Kurt, B | 1 |
| Ozcan, A | 1 |
| Kaya, O | 1 |
| Tufan, T | 1 |
| Akkuş, A | 1 |
| Gülmen, M | 1 |
| Cevik, A | 1 |
| Bildik, N | 1 |
| Sad, O | 1 |
| Oztürk, E | 1 |
| Barişik, NO | 1 |
| Shen, H | 1 |
| Ma, H | 1 |
| Jia, JD | 2 |
| Parsons, SA | 1 |
| Millay, DP | 1 |
| Sargent, MA | 1 |
| McNally, EM | 1 |
| Molkentin, JD | 1 |
| Nursal, TZ | 1 |
| Bal, N | 1 |
| Anarat, R | 1 |
| Colakoglu, T | 1 |
| Noyan, T | 1 |
| Ammar, YA | 1 |
| Ismail, MM | 1 |
| El-Sehrawi, HM | 1 |
| Noaman, E | 1 |
| Bayomi, AH | 1 |
| Shawer, TZ | 1 |
| Byer, KJ | 2 |
| Chan, ES | 1 |
| Fernandez, P | 1 |
| Merchant, AA | 1 |
| Montesinos, MC | 1 |
| Trzaska, S | 1 |
| Desai, A | 1 |
| Tung, CF | 1 |
| Khoa, DN | 1 |
| Pillinger, MH | 1 |
| Reiss, AB | 1 |
| Tomic-Canic, M | 1 |
| Chen, JF | 1 |
| Schwarzschild, MA | 1 |
| Cronstein, BN | 1 |
| Hu, P | 1 |
| Gao, ZC | 1 |
| Lakatos, HF | 1 |
| Burgess, HA | 1 |
| Thatcher, TH | 1 |
| Redonnet, MR | 1 |
| Hernady, E | 1 |
| Williams, JP | 1 |
| Sime, PJ | 1 |
| Zhang, HQ | 1 |
| Yau, YF | 1 |
| Szeto, KY | 1 |
| Chan, WT | 1 |
| Wong, J | 1 |
| Potter, JJ | 2 |
| Rennie-Tankersley, L | 1 |
| Novitskiy, G | 1 |
| Sipes, J | 1 |
| Mezey, E | 2 |
| Shinagawa, K | 1 |
| Ploplis, VA | 1 |
| Castellino, FJ | 1 |
| Kirsch, R | 1 |
| Sijtsema, HP | 1 |
| Tlali, M | 1 |
| Marais, AD | 1 |
| Hall, Pde L | 1 |
| Douglas, N | 1 |
| Olmedo, P | 1 |
| Douglas, CR | 1 |
| Monte, O | 1 |
| Zhang, GC | 1 |
| Posma, LA | 2 |
| Xu, D | 1 |
| Liao, ZX | 1 |
| Gomes, AT | 1 |
| Cunha, LM | 1 |
| Bastos, CG | 1 |
| Medrado, BF | 1 |
| Assis, BC | 1 |
| Nayak, BS | 3 |
| Isitor, GN | 1 |
| Maxwell, A | 1 |
| Bhogadi, V | 1 |
| Ramdath, DD | 1 |
| Omenetti, A | 1 |
| Li, YX | 1 |
| McCall, SJ | 1 |
| Jung, Y | 1 |
| Sicklick, JK | 1 |
| Huang, J | 1 |
| Choi, S | 1 |
| Suzuki, A | 1 |
| Torres-González, E | 1 |
| Ritzenthaler, J | 1 |
| Speck, SH | 1 |
| Roman, J | 1 |
| Brigham, K | 1 |
| Stecenko, A | 1 |
| Cao, Z | 1 |
| Zhou, S | 1 |
| Ye, Z | 1 |
| Izumo, T | 1 |
| Kondo, M | 1 |
| Nagai, A | 2 |
| Majumdar, M | 1 |
| Nayeem, N | 1 |
| Kamath, JV | 1 |
| Asad, M | 1 |
| Li, YQ | 1 |
| Arafa, HM | 1 |
| Abdel-Wahab, MH | 1 |
| El-Shafeey, MF | 1 |
| Badary, OA | 1 |
| Hamada, FM | 1 |
| Cao, BQ | 1 |
| Lin, JZ | 1 |
| Zhong, YS | 1 |
| Huang, SB | 1 |
| Lin, N | 1 |
| Tang, ZF | 1 |
| Xiang, P | 1 |
| Xu, RY | 1 |
| Mizushige, T | 1 |
| Mizushige, K | 2 |
| Miyatake, A | 1 |
| Kishida, T | 1 |
| Ebihara, K | 1 |
| Aytekin, FO | 2 |
| Aydin, C | 2 |
| Kabay, B | 2 |
| Demir, EM | 1 |
| Tekin, K | 2 |
| Hagiwara, S | 1 |
| Iwasaka, H | 1 |
| Matsumoto, S | 1 |
| Noguchi, T | 1 |
| Ibañez, P | 1 |
| Solis, N | 1 |
| Pizarro, M | 1 |
| Aguayo, G | 1 |
| Duarte, I | 1 |
| Miquel, JF | 1 |
| Accatino, L | 1 |
| Arrese, M | 1 |
| Sacar, M | 1 |
| Ozden, A | 1 |
| Panoskaltsis-Mortari, A | 1 |
| Tram, KV | 1 |
| Price, AP | 1 |
| Wendt, CH | 1 |
| Blazar, BR | 1 |
| Tander, B | 2 |
| Bicakci, U | 2 |
| Kilicoglu-Aydin, B | 2 |
| Ariturk, E | 2 |
| Rizalar, R | 2 |
| Bernay, F | 2 |
| Fickert, P | 1 |
| Stöger, U | 1 |
| Fuchsbichler, A | 1 |
| Moustafa, T | 1 |
| Marschall, HU | 1 |
| Weiglein, AH | 1 |
| Tsybrovskyy, O | 1 |
| Jaeschke, H | 1 |
| Zatloukal, K | 1 |
| Denk, H | 1 |
| Trauner, M | 1 |
| Hirakawa, H | 1 |
| Pierce, RA | 1 |
| Bingol-Karakoc, G | 1 |
| Karaaslan, C | 1 |
| Weng, M | 1 |
| Shi, GP | 1 |
| Saad, A | 1 |
| Weber, E | 1 |
| Mariani, TJ | 1 |
| Starcher, B | 2 |
| Cataltepe, S | 1 |
| Raju, SS | 2 |
| Rao, AV | 1 |
| Fang, HL | 1 |
| Lin, HY | 1 |
| Chan, MC | 1 |
| Lin, WL | 1 |
| Saravanan, N | 1 |
| Nalini, N | 1 |
| Makay, O | 1 |
| Bicakci, T | 1 |
| Ersin, S | 1 |
| Salam, OM | 1 |
| El-Batran, SA | 1 |
| Abdallah, HM | 1 |
| Shaffie, NM | 1 |
| Hie, M | 1 |
| Shimono, M | 1 |
| Fujii, K | 1 |
| Chan, FC | 1 |
| Kennedy, C | 1 |
| Hanson, RP | 1 |
| O'Sullivan, B | 1 |
| Kelly, J | 1 |
| Bouchier-Hayes, D | 1 |
| Tarhan, OR | 1 |
| Barut, I | 1 |
| Sezik, M | 1 |
| Zheng, MH | 1 |
| Dai, MS | 1 |
| Lin, LF | 1 |
| Na, Y | 1 |
| Zhang, XX | 1 |
| Zhang, XD | 1 |
| Yuan, HP | 1 |
| Hu, XL | 1 |
| Zheng, W | 1 |
| Ozercan, IH | 1 |
| Evren, B | 1 |
| Metin, K | 1 |
| Satomi, Y | 1 |
| Sakaguchi, K | 1 |
| Kasahara, Y | 1 |
| Akahori, F | 1 |
| Nakamura, H | 1 |
| Seki, M | 1 |
| Shiraishi, Y | 1 |
| Furuuchi, M | 1 |
| Nakajima, T | 1 |
| Tsujimura, S | 1 |
| Shirahata, T | 1 |
| Nakamura, M | 1 |
| Minematsu, N | 1 |
| Yamasaki, M | 1 |
| Tateno, H | 1 |
| Ishizaka, A | 1 |
| Luttrell, IP | 1 |
| Swee, M | 1 |
| Parks, WC | 1 |
| Chitaley, K | 1 |
| Topaloglu, B | 1 |
| Aydin, O | 1 |
| Ayyildiz, SH | 1 |
| Chalapathi Rao, AV | 1 |
| Ask, K | 1 |
| Labiris, R | 1 |
| Farkas, L | 1 |
| Moeller, A | 1 |
| Froese, A | 1 |
| Farncombe, T | 1 |
| McClelland, GB | 1 |
| Inman, M | 1 |
| Gauldie, J | 1 |
| Kolb, MR | 1 |
| Hoogendoorn, RJ | 1 |
| Helder, MN | 1 |
| Kroeze, RJ | 1 |
| Bank, RA | 1 |
| Smit, TH | 1 |
| Wuisman, PI | 1 |
| Huang, HS | 1 |
| Ma, MC | 1 |
| Waseda, Y | 1 |
| Yasui, M | 1 |
| Nishizawa, Y | 2 |
| Inuzuka, K | 1 |
| Takato, H | 1 |
| Ichikawa, Y | 1 |
| Tagami, A | 1 |
| Fujimura, M | 1 |
| Nakao, S | 1 |
| Mályusz, M | 1 |
| Braun, D | 1 |
| Trivedi, P | 1 |
| Mowat, AP | 1 |
| Prieur, DJ | 1 |
| Young, DM | 1 |
| Counts, DF | 1 |
| Hatch, GE | 1 |
| Raub, JA | 1 |
| Graham, JA | 1 |
| Jimenez, SA | 2 |
| Millan, A | 1 |
| Bashey, RI | 2 |
| Coulais, Y | 1 |
| Marcelon, G | 1 |
| Cros, J | 1 |
| Guiraud, R | 1 |
| Ballardini, G | 1 |
| Degli Esposti, S | 1 |
| Bianchi, FB | 1 |
| de Giorgi, LB | 1 |
| Faccani, A | 1 |
| Biolchini, L | 1 |
| Busachi, CA | 1 |
| Pisi, E | 1 |
| Benveniste, K | 1 |
| Thut, P | 1 |
| Lin, HJ | 1 |
| Benson, DR | 1 |
| Riggins, RS | 1 |
| Rucker, RB | 1 |
| Abbott, UK | 1 |
| Karamanoukian, HL | 2 |
| Glick, PL | 2 |
| Wilcox, DT | 2 |
| O'Toole, SJ | 1 |
| Rossman, JE | 2 |
| Azizkhan, RG | 2 |
| Hassett, MJ | 1 |
| Nagareda, T | 1 |
| Tanaka, A | 1 |
| Terada, N | 1 |
| Imakon, Y | 1 |
| Shiomi, H | 1 |
| Matsubara, H | 1 |
| Noro, A | 1 |
| Wild, JS | 1 |
| García-Moreno, C | 1 |
| Calvo, OM | 1 |
| Herrero, S | 1 |
| Martín, E | 1 |
| Suquía, B | 1 |
| San Román, JI | 1 |
| Martín, M | 1 |
| García-Talavera, JR | 1 |
| Calvo, JJ | 1 |
| del Pino, J | 1 |
| Araki, T | 2 |
| Shimizu, M | 1 |
| Yoshio, H | 1 |
| Ino, H | 1 |
| Mabuchi, H | 1 |
| Takeda, R | 1 |
| Delmas, PD | 1 |
| Vergnaud, P | 1 |
| Arlot, ME | 1 |
| Pastoureau, P | 1 |
| Meunier, PJ | 1 |
| Nilssen, MH | 1 |
| Heeneman, S | 1 |
| Leenders, PJ | 1 |
| Aarts, PJ | 1 |
| Smits, JF | 1 |
| Arends, JW | 1 |
| Daemen, MJ | 1 |
| Hirose, N | 1 |
| Lynch, DA | 1 |
| Cherniack, RM | 1 |
| Doherty, DE | 1 |
| Covington, DS | 1 |
| Xue, H | 1 |
| Pizzini, R | 1 |
| Lally, KP | 1 |
| Andrassy, RJ | 2 |
| Sims, NA | 2 |
| Morris, HA | 2 |
| Moore, RJ | 2 |
| Durbridge, TC | 2 |
| Stein-Streilein, J | 3 |
| Sakaida, I | 1 |
| Kubota, M | 1 |
| Kayano, K | 1 |
| Takenaka, K | 1 |
| Mori, K | 1 |
| Okita, K | 1 |
| Gelzleichter, TR | 2 |
| Harkema, J | 1 |
| Hawk, S | 1 |
| Leeder, RG | 1 |
| Evans, CD | 1 |
| Koopmans, SJ | 1 |
| van der Wee-Pals, L | 1 |
| Löwik, CW | 1 |
| Papapoulos, SE | 1 |
| Jablonski, G | 1 |
| Klem, KH | 1 |
| Attramadal, A | 1 |
| Dahl, E | 1 |
| Rønningen, H | 1 |
| Gautvik, KM | 1 |
| Haug, E | 1 |
| Gordeladze, JO | 1 |
| Bishop, J | 1 |
| Greenham, AK | 1 |
| Lewis, EJ | 1 |
| Walker, RM | 1 |
| Witschi, H | 1 |
| Unemori, EN | 1 |
| Beck, LS | 1 |
| Lee, WP | 1 |
| Siegel, M | 1 |
| Keller, G | 1 |
| Liggitt, HD | 1 |
| Bauer, EA | 1 |
| Amento, EP | 1 |
| Bocchieri, MH | 1 |
| Christner, PJ | 1 |
| Henriksen, PD | 1 |
| Evans, DM | 1 |
| McAree, K | 1 |
| Guyton, DP | 1 |
| Hawkins, N | 1 |
| Stakleff, K | 1 |
| Takeshita, N | 1 |
| Ishida, H | 1 |
| Koh, G | 1 |
| Kurose, T | 1 |
| Tsuji, K | 1 |
| Okamoto, Y | 1 |
| Ikeda, H | 1 |
| Seino, Y | 1 |
| Colville-Nash, PR | 1 |
| el-Ghazaly, M | 1 |
| Willoughby, DA | 2 |
| Reinhart, PG | 1 |
| Lai, YL | 1 |
| Gairola, CG | 1 |
| Skalski, J | 1 |
| Machej, L | 1 |
| Radziszewska, E | 1 |
| Perlik, T | 1 |
| Wites, M | 1 |
| Pawlak, S | 1 |
| Sleczka, B | 1 |
| Bochenek, A | 1 |
| Wedrychowska, A | 1 |
| Gerling, B | 1 |
| Becker, M | 1 |
| Waldschmidt, J | 1 |
| Rehmann, M | 1 |
| Odetti, P | 1 |
| Traverso, N | 1 |
| Cosso, L | 1 |
| Noberasco, G | 1 |
| Pronzato, MA | 1 |
| Marinari, UM | 1 |
| Schäffer, MR | 1 |
| Tantry, U | 1 |
| Ahrendt, GM | 1 |
| Wasserkrug, HL | 2 |
| Barbul, A | 2 |
| Wiggers, H | 1 |
| Klebe, T | 1 |
| Heickendorff, L | 1 |
| Høst, NB | 1 |
| Danielsen, CC | 1 |
| Baandrup, U | 1 |
| Andersen, HR | 1 |
| Magnuson, SK | 1 |
| Booth, R | 1 |
| Porter, S | 1 |
| Gorski, JP | 1 |
| Brooks, WW | 1 |
| Hayes, JA | 1 |
| Robinson, KG | 1 |
| Sen, S | 1 |
| Conrad, CH | 1 |
| Bing, OH | 2 |
| Landis, CA | 1 |
| Whitney, JD | 1 |
| Turgut, M | 1 |
| Onol, B | 1 |
| Kiliniç, K | 1 |
| Tahta, K | 1 |
| Yamazaki, C | 2 |
| Hoshino, J | 2 |
| Hori, Y | 4 |
| Sekiguchi, T | 2 |
| Miyauchi, S | 2 |
| Mizuno, S | 2 |
| Horie, K | 2 |
| Jørgensen, PH | 1 |
| Huang, HF | 1 |
| You, JS | 1 |
| Zhao, W | 1 |
| Yu, R | 1 |
| Hou, XM | 1 |
| Moore, AR | 1 |
| Greenslade, KJ | 1 |
| Alam, CA | 1 |
| Smith, RL | 1 |
| Kajiyama, G | 1 |
| Schurman, DJ | 1 |
| Harris, A | 1 |
| Schropp, A | 1 |
| Messmer, K | 2 |
| Franco, L | 1 |
| Najvar, L | 1 |
| Gomez, BL | 1 |
| Restrepo, S | 1 |
| Graybill, JR | 1 |
| Restrepo, A | 1 |
| Shimizu, T | 1 |
| Kuroda, T | 1 |
| Hata, S | 1 |
| Fukagawa, M | 1 |
| Kurokawa, K | 1 |
| Venkatesan, N | 1 |
| Punithavathi, D | 1 |
| Chandrakasan, G | 1 |
| Tanyel, FC | 1 |
| Müftüoğlu, S | 1 |
| Cakar, N | 1 |
| Büyükpamukçu, N | 1 |
| Hiçsönmez, A | 1 |
| Moore, G | 1 |
| Liao, S | 1 |
| Curci, JA | 1 |
| Starcher, BC | 1 |
| Martin, RL | 1 |
| Hendricks, RT | 1 |
| Chen, JJ | 1 |
| Thompson, RW | 1 |
| Uchii, M | 1 |
| Takashima, M | 1 |
| Sugiyama, T | 1 |
| Kosaka, N | 1 |
| Natori, J | 1 |
| Shimizu, K | 1 |
| Nagahama, M | 1 |
| Tanaka, S | 1 |
| Song, X | 1 |
| Bao, M | 1 |
| Madden, JW | 1 |
| Gertman, PM | 1 |
| Peacock, EE | 1 |
| Katayama, I | 2 |
| Mizushima, Y | 1 |
| Nishioka, K | 2 |
| Takahashi, Y | 1 |
| Noma, T | 1 |
| Yao, L | 1 |
| Kiyomoto, H | 1 |
| Hosomi, N | 1 |
| Abe, Y | 1 |
| Ohmori, K | 1 |
| Matsuo, H | 1 |
| Sarin, SK | 1 |
| Sharma, G | 1 |
| Banerjee, S | 1 |
| Kathayat, R | 1 |
| Malhotra, V | 1 |
| Gupta, A | 1 |
| Jain, GK | 1 |
| Raghubir, R | 1 |
| Baykal, A | 1 |
| Ozdemir, A | 1 |
| Sayek, I | 1 |
| Cho, JJ | 1 |
| Hocher, B | 1 |
| Herbst, H | 1 |
| Ruehl, M | 1 |
| Hahn, EG | 2 |
| Riecken, EO | 1 |
| Turcani, M | 1 |
| Rupp, H | 1 |
| Park, EJ | 1 |
| Nan, JX | 1 |
| Kim, JY | 1 |
| Kang, HC | 1 |
| Choi, JH | 1 |
| Lee, SJ | 1 |
| Lee, BH | 1 |
| Kim, SJ | 1 |
| Lee, JH | 1 |
| Kim, YC | 1 |
| Sohn, DH | 1 |
| Aoshiba, K | 1 |
| Yasui, S | 1 |
| Tamaoki, J | 1 |
| Gurujeyalakshmi, G | 1 |
| Carney, SL | 1 |
| Dohi, M | 1 |
| Hasegawa, T | 1 |
| Yamamoto, K | 1 |
| Marshall, BC | 1 |
| Urschel, JD | 1 |
| Petrelli, NJ | 1 |
| Huang, SH | 1 |
| Hubbs, AF | 2 |
| Stanley, CF | 1 |
| Vallyathan, V | 1 |
| Schnabel, PC | 1 |
| Rojanasakul, Y | 1 |
| Ma, JK | 1 |
| Banks, DE | 1 |
| Weissman, DN | 1 |
| Yoshiyama, M | 1 |
| Izumi, Y | 1 |
| Kawano, H | 1 |
| Kimoto, M | 1 |
| Zhan, Y | 1 |
| Iwao, H | 1 |
| Woodiwiss, AJ | 1 |
| Tsotetsi, OJ | 1 |
| Sprott, S | 1 |
| Lancaster, EJ | 1 |
| Mela, T | 1 |
| Chung, ES | 1 |
| Meyer, TE | 1 |
| Norton, GR | 1 |
| Zhang-Hoover, J | 1 |
| Sutton, A | 1 |
| Shimizu, Y | 1 |
| Dobashi, K | 1 |
| Iizuka, K | 1 |
| Horie, T | 1 |
| Tukagoshi, H | 1 |
| Nakazawa, T | 1 |
| Nakazato, Y | 1 |
| Mori, M | 2 |
| Takahashi, F | 1 |
| Takahashi, K | 1 |
| Okazaki, T | 1 |
| Maeda, K | 1 |
| Ienaga, H | 1 |
| Maeda, M | 1 |
| Kon, S | 1 |
| Uede, T | 1 |
| Fukuchi, Y | 1 |
| Pauluhn, J | 1 |
| Baumann, M | 1 |
| Hirth-Dietrich, C | 1 |
| Rosenbruch, M | 1 |
| Arras, M | 1 |
| Huaux, F | 1 |
| Vink, A | 1 |
| Delos, M | 1 |
| Coutelier, JP | 1 |
| Many, MC | 1 |
| Barbarin, V | 1 |
| Renauld, JC | 1 |
| Lison, D | 1 |
| Xu, Z | 1 |
| Westrick, RJ | 1 |
| Shen, YC | 1 |
| Eitzman, DT | 1 |
| Souza, MM | 1 |
| Paraná, R | 1 |
| Trepo, C | 1 |
| Oliveira, I | 1 |
| Ostrowska, Z | 2 |
| Kos-Kudla, B | 2 |
| Swietochowska, E | 1 |
| Marek, B | 2 |
| Kajdaniuk, D | 2 |
| Górski, J | 1 |
| Maeyama, T | 1 |
| Kuwano, K | 1 |
| Kawasaki, M | 1 |
| Kunitake, R | 1 |
| Hagimoto, N | 1 |
| Hara, N | 1 |
| Brok, HP | 1 |
| Tekoppele, JM | 1 |
| Hakimi, J | 1 |
| Kerwin, JA | 1 |
| Nijenhuis, EM | 1 |
| De Groot, CW | 1 |
| Bontrop, RE | 1 |
| 't Hart, BA | 1 |
| Yasui, H | 1 |
| Gabazza, EC | 1 |
| Tamaki, S | 1 |
| Kobayashi, T | 1 |
| Hataji, O | 1 |
| Yuda, H | 1 |
| Shimizu, S | 1 |
| Adachi, Y | 1 |
| Taguchi, O | 1 |
| Muguerza, B | 1 |
| Castilla-Cortázar, I | 1 |
| Quiroga, J | 1 |
| Santidrián, S | 1 |
| Prieto, J | 1 |
| Veihelmann, A | 1 |
| Hofbauer, A | 1 |
| Refior, HJ | 1 |
| Kriegsmann, J | 1 |
| Sawall, S | 1 |
| Splinther, J | 1 |
| Sommer, M | 1 |
| Nwogu, JI | 1 |
| Geenen, D | 1 |
| Bean, M | 1 |
| Brenner, MC | 1 |
| Huang, X | 1 |
| Buttrick, PM | 1 |
| Peters-Golden, M | 1 |
| Bailie, M | 1 |
| Marshall, T | 1 |
| Wilke, C | 1 |
| Toews, GB | 1 |
| Weng, HL | 1 |
| Cai, WM | 1 |
| Liu, RH | 1 |
| Chen, W | 1 |
| Lu, S | 1 |
| Shi, J | 1 |
| Candan, F | 1 |
| Alagözlü, H | 1 |
| Demirbilek, S | 1 |
| Aydin, G | 1 |
| Yücesan, S | 1 |
| Vural, H | 1 |
| Bitiren, M | 1 |
| Ciesielska-Kopacz, N | 1 |
| Jugdutt, BI | 1 |
| Menon, V | 1 |
| Kumar, D | 1 |
| Idikio, H | 1 |
| Taylor, MD | 1 |
| Roberts, JR | 1 |
| Reasor, MJ | 1 |
| Antonini, JM | 1 |
| Saito, E | 1 |
| Fujimoto, M | 1 |
| Hasegawa, M | 1 |
| Komura, K | 1 |
| Hamaguchi, Y | 1 |
| Kaburagi, Y | 1 |
| Nagaoka, T | 1 |
| Takehara, K | 1 |
| Tedder, TF | 1 |
| Sato, S | 1 |
| Matsuoka, H | 1 |
| Arai, T | 1 |
| Goya, S | 1 |
| Kida, H | 1 |
| Morishita, H | 1 |
| Fujiwara, H | 1 |
| Tachibana, I | 1 |
| Osaki, T | 1 |
| Griffin, M | 1 |
| Smith, LL | 1 |
| Wynne, J | 1 |
| Whitear, SH | 1 |
| Basu, TK | 1 |
| Hoag, GN | 1 |
| Brown, RG | 1 |
| Smart, ME | 1 |
| Subden, RE | 1 |
| Frederiksen, DW | 1 |
| Hoffnung, JM | 1 |
| Frederiksen, RT | 1 |
| Williams, RB | 1 |
| Yarrington, JT | 1 |
| Capen, CC | 2 |
| Black, HE | 1 |
| Re, R | 1 |
| Potts, JT | 1 |
| Geho, WB | 1 |
| Moczar, E | 1 |
| Berenholc, S | 1 |
| Lamendin, H | 1 |
| Allard, R | 1 |
| Robert, AM | 1 |
| Yermakoff, JK | 1 |
| Fuller, GC | 1 |
| Rodil, JV | 1 |
| Suzuki, Y | 1 |
| Kohara, U | 1 |
| Ito, M | 1 |
| Kursh, ED | 1 |
| Klein, L | 1 |
| Schmitt, J | 1 |
| Kayal, S | 1 |
| Persky, L | 1 |
| Percarpio, B | 1 |
| Fischer, JJ | 1 |
| Taceva, J | 1 |
| Behrens, F | 1 |
| Shepard, N | 1 |
| Mitchell, N | 1 |
| Piller, NB | 1 |
| Grasedyck, K | 1 |
| Lindner, J | 1 |
| Ehrlich, MG | 1 |
| Mankin, HJ | 1 |
| Jones, H | 1 |
| Grossman, A | 1 |
| Crispen, C | 1 |
| Ancona, D | 1 |
| Paquet, KJ | 1 |
| Kamphausen, U | 1 |
| Lane, JM | 2 |
| Bora, FW | 2 |
| Black, J | 2 |
| Fischer, GM | 1 |
| Cox, RH | 1 |
| Detweiler, DK | 1 |
| Zia, S | 1 |
| Zyłka-Włoszczyk, M | 3 |
| Ociepiński, M | 3 |
| Szaflarska-Stojko, E | 4 |
| Suzawa, H | 1 |
| Kikuchi, S | 1 |
| Ichikawa, K | 1 |
| Arai, N | 1 |
| Tazawa, S | 1 |
| Tsuchiya, O | 1 |
| Momose, Y | 1 |
| Shibata, N | 1 |
| Sugimoto, C | 1 |
| Hamano, S | 1 |
| Seiki, M | 2 |
| Aita, H | 2 |
| Ueki, S | 1 |
| Yoneta, T | 2 |
| Takemasa, T | 2 |
| Morita, H | 2 |
| Chaki, K | 2 |
| Tagashira, E | 3 |
| Altman, RD | 2 |
| Kates, J | 1 |
| Chun, LE | 1 |
| Dean, DD | 2 |
| Eyre, D | 1 |
| Hayashi, N | 1 |
| Sasaki, Y | 1 |
| Kono, M | 1 |
| Kasahara, A | 1 |
| Fusamoto, H | 1 |
| Imai, Y | 1 |
| Kamada, T | 1 |
| Axelsson, S | 1 |
| Holmlund, A | 1 |
| Hjerpe, A | 1 |
| Randhawa, AK | 1 |
| Singal, PK | 1 |
| Goulding, A | 1 |
| Gold, E | 1 |
| Feng, W | 1 |
| Driscoll, KE | 1 |
| Maurer, JK | 1 |
| Poynter, J | 1 |
| Higgins, J | 1 |
| Asquith, T | 1 |
| Miller, NS | 1 |
| Seto, K | 1 |
| Yamada, H | 1 |
| Nakamura, T | 1 |
| Nagai, Y | 1 |
| Yamato, H | 1 |
| Orimo, H | 1 |
| Kucharz, EI | 2 |
| Olczyk, K | 2 |
| Sonecki, P | 2 |
| Tetley, TD | 1 |
| Phillips, GJ | 1 |
| Guz, A | 1 |
| Fox, B | 1 |
| Park, PO | 1 |
| Alumets, J | 1 |
| Arvidsson, S | 1 |
| Grimelius, L | 1 |
| Haglund, U | 1 |
| Bosma, A | 1 |
| Seifert, WF | 1 |
| Wilson, JH | 1 |
| Roholl, PJ | 1 |
| Brouwer, A | 1 |
| Knook, DL | 1 |
| Szymczykiewicz, K | 1 |
| Olczyk, D | 1 |
| Yoshida, A | 1 |
| Omata, T | 1 |
| Yamaguchi, I | 1 |
| Kurimoto, T | 1 |
| Abbas, HL | 1 |
| Kato, K | 1 |
| Wein, AJ | 1 |
| Radzinski, C | 1 |
| Longhurst, PA | 1 |
| McGuire, EJ | 1 |
| Miller, LF | 1 |
| Elbadawi, A | 1 |
| Levin, RM | 1 |
| Mossman, BT | 1 |
| Marsh, JP | 1 |
| Sesko, A | 1 |
| Hill, S | 1 |
| Shatos, MA | 1 |
| Doherty, J | 1 |
| Petruska, J | 1 |
| Adler, KB | 1 |
| Hemenway, D | 1 |
| Mickey, R | 1 |
| Hennessey, PJ | 1 |
| Black, CT | 1 |
| Frankle, M | 1 |
| Borrelli, J | 1 |
| Virmani, R | 1 |
| Osmialowski, AF | 1 |
| Kolodgie, FD | 1 |
| Forman, MB | 1 |
| Ching, SV | 1 |
| Norrdin, RW | 1 |
| Fettman, MJ | 1 |
| LeCouteur, RA | 1 |
| Dinges, HP | 1 |
| Redl, H | 1 |
| Thurnher, M | 1 |
| Schiesser, A | 1 |
| Schlag, G | 1 |
| Knight, KR | 1 |
| Collopy, PA | 1 |
| McCann, JJ | 1 |
| Vanderkolk, CA | 1 |
| Coe, SA | 1 |
| Barton, RM | 1 |
| Chen, HC | 1 |
| O'Brien, BM | 1 |
| Harrison, JH | 1 |
| Lazo, JS | 1 |
| Adamson, IY | 1 |
| King, GM | 1 |
| Bowden, DH | 1 |
| Shawe, T | 1 |
| Rotter, SM | 1 |
| Efron, JE | 1 |
| Badawy, SB | 1 |
| Daniels, JM | 1 |
| Muniz, OE | 1 |
| Howell, DS | 1 |
| Ruwart, MJ | 1 |
| Wilkinson, KF | 1 |
| Rush, BD | 1 |
| Vidmar, TJ | 1 |
| Peters, KM | 1 |
| Henley, KS | 1 |
| Appelman, HD | 1 |
| Kim, KY | 1 |
| Müller, A | 1 |
| Machnik, F | 1 |
| Zimmermann, T | 1 |
| Schubert, H | 1 |
| Hoidal, JR | 1 |
| Niewoehner, DE | 1 |
| Rao, NV | 1 |
| Hibbs, MS | 1 |
| Rosol, TJ | 1 |
| Weisbrode, SE | 1 |
| Horst, RL | 1 |
| Godsall, JW | 1 |
| Burtis, WJ | 1 |
| Insogna, KL | 1 |
| Broadus, AE | 1 |
| Stewart, AF | 1 |
| Chiariello, M | 1 |
| Ambrosio, G | 1 |
| Cappelli-Bigazzi, M | 1 |
| Perrone-Filardi, P | 1 |
| Brigante, F | 1 |
| Sifola, C | 1 |
| Haydock, DA | 1 |
| Flint, MH | 1 |
| Hyde, KF | 1 |
| Reilly, HC | 1 |
| Poole, CA | 1 |
| Hill, GL | 1 |
| van Rongen, E | 1 |
| Tan, CH | 1 |
| Durham, SK | 1 |
| Lipscomb, MF | 1 |
| Fisch, H | 1 |
| Whitney, PL | 1 |
| Osborn, TG | 1 |
| Moore, TL | 1 |
| Fischer, VW | 1 |
| Bowersox, JC | 1 |
| Hackett, RL | 1 |
| Beglarian, AG | 1 |
| Aznaurian, AV | 1 |
| Gang, NF | 1 |
| Kalant, N | 1 |
| De Haan, BB | 1 |
| Ellis, H | 1 |
| Wilks, M | 1 |
| Matsushita, S | 1 |
| Fanburg, BL | 1 |
| Levine, HJ | 1 |
| Skosey, JL | 1 |
| Aschienbrenner, V | 1 |
| Zak, R | 1 |
| Rabinowitz, M | 1 |
| Religa, Z | 1 |
| Maśliński, C | 1 |
| Kuncová, M | 1 |
| Havránková, J | 1 |
| Holusa, R | 1 |
| Palecek, F | 1 |
| Levine, N | 1 |
| Seifter, E | 1 |
| Connerton, C | 1 |
| Levenson, SM | 1 |
| Russell, JE | 1 |
| Avioli, LV | 1 |
| Thompson, RC | 1 |
| Hähnel, H | 1 |
| Lindenhayn, K | 1 |
| Mühlbach, R | 1 |
| Schmidt, UJ | 1 |
| Thomas, J | 1 |
| Thomas, E | 1 |
| Duburque, MT | 1 |
| Melon, JM | 1 |
| Monsaingeon, A | 1 |
| Ranek, L | 1 |
| Bremmelgaard, A | 1 |
| Dupont, B | 1 |
| Jorgensen, M | 1 |
| Keiding, S | 1 |
| Thomsen, P | 1 |
| Tyrsted, G | 1 |
| Ehrlich, HP | 1 |
| Grislis, G | 1 |
| Hunt, TK | 1 |
| Prockop, DJ | 1 |
| Heppenstall, RB | 1 |
| Yamakawa, T | 1 |
| Patin, CS | 1 |
| Sobel, S | 1 |
| Morgenstern, L | 1 |
| Gudbjarnason, S | 1 |
| Puri, PS | 1 |
| Mathes, P | 1 |
| Halme, J | 1 |
| Uitto, J | 1 |
| Kahanpää, K | 1 |
| Karhunen, P | 1 |
| Lindy, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults With COVID-19[NCT04394416] | Phase 3 | 204 participants (Anticipated) | Interventional | 2020-06-02 | Active, not recruiting | ||
| Effect of Supplementation With b- Hydroxy Methyl Butyrate and Glutamine in Wound Healing Histology in Type 2 Diabetes and Controls Bloody Areas[NCT03782155] | Phase 4 | 30 participants (Anticipated) | Interventional | 2021-06-01 | Not yet recruiting | ||
| Comparative Study Between Fat Injection And Platelet Rich Plasma IN Post Burn Facial Scar Clinical And Histopathological Assessment[NCT04557514] | 60 participants (Anticipated) | Interventional | 2020-10-01 | Not yet recruiting | |||
| Nutritional Regulation of Wound Inflammation: Part III[NCT02332993] | 22 participants (Actual) | Observational | 2014-12-31 | Completed | |||
| Preoperative Embolization of the Inferior Mesenteric Artery in Colorectal Surgery[NCT05422560] | 30 participants (Anticipated) | Interventional | 2022-09-06 | Recruiting | |||
| A Trial of Montelukast for Maintenance Therapy of Eosinophilic Esophagitis in Children[NCT01458418] | 4 participants (Actual) | Interventional | 2011-12-31 | Terminated (stopped due to Inability to complete enrollment due to difficulty in finding subjects) | |||
| Pirfenidone Effect on the Recovery of Renal Function in Patients With Septic Acute Kidney Injury[NCT02530359] | Phase 4 | 90 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Eosinophils/high powered field(hpf) in the mid esophagus will be measured after 12 weeks of therapy. (NCT01458418)
Timeframe: 12 weeks
| Intervention | Eosinophils/HPF (Mean) |
|---|---|
| Subjects Whose Arm is Unknown Due to Not Being Unblinded | 8 |
3 reviews available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Growth hormone, skin and wound healing--experimental studies in the rat.
Topics: Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; Female; Human Growth Hormone; Hu | 1997 |
Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Animals; Bone Neoplasms; Calcium; Cyclic AMP; Disease Model | 1986 |
Calcium oxalate urolithiasis in the rat: is it a model for human stone disease? A review of recent literature.
Topics: Animals; Calcium Oxalate; Diet; Disease Models, Animal; Ethylene Glycols; Female; Foreign Bodies; Gl | 1985 |
1 trial available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis.
Topics: Animals; Antineoplastic Agents; Biopsy; Carbon Tetrachloride; Dimethylnitrosamine; Disease Models, A | 2001 |
605 other studies available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary F | 2022 |
Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis.
Topics: Animals; Cytokines; Diet, High-Fat; Disease Models, Animal; Fructose; Hydroxyproline; Liver; Liver C | 2021 |
Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, | 2022 |
Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT.
Topics: Animals; Autophagy; Disease Models, Animal; Diterpenes, Kaurane; Hydroxyproline; Inflammation; Lipop | 2022 |
Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL | 2022 |
Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis.
Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Disease Models, Animal; Fibrosis; He | 2022 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammat | 2023 |
Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin.
Topics: Animals; Bleomycin; Cells, Cultured; Cytoprotection; Disease Models, Animal; Extracellular Signal-Re | 2019 |
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline | 2020 |
[Preventive and therapeutic effects of safflower water extract on systemic scleroderma in mice and its mechanism].
Topics: Animals; Bleomycin; Carthamus tinctorius; Connective Tissue Growth Factor; Disease Models, Animal; H | 2019 |
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Disease Models, Animal; Female; Glycolates; Hu | 2020 |
Effects of thalidomide on Th17, Treg cells and TGF-β1/Smad3 pathway in a mouse model of systemic sclerosis.
Topics: Animals; Cytokines; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Immunosuppressive Agen | 2020 |
Ursodeoxycholic acid alleviates experimental liver fibrosis involving inhibition of autophagy.
Topics: Animals; Autophagy; Blotting, Western; Cell Line; Disease Models, Animal; Humans; Hydroxychloroquine | 2020 |
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage.
Topics: Aged; Animals; Behavior, Animal; Cartilage, Articular; Chondrocytes; Collagen Type II; Disease Model | 2020 |
Expression and significance of miR-223 in rats with pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Inflammation; Male; MicroRNAs; Pulmonary Fibrosis; | 2020 |
Design, synthesis, and biological evaluation of 4-phenoxybenzenesulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2020 |
Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Arterial Pressure; Cardiomyopathies; Colla | 2021 |
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Topics: Administration, Oral; Alkalies; Amino Acid Oxidoreductases; Amino Acids; Animals; Bleomycin; Citrus; | 2021 |
IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis.
Topics: Aged; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Disease Models, Anima | 2021 |
Expression of the α7 Nicotinic Acetylcholine Receptor Is Critically Required for the Antifibrotic Effect of PHA-543613 on Skin Fibrosis.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bleomycin; Bridged Bicyclo Compounds, Heterocyclic | 2022 |
The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats.
Topics: Animals; Benzhydryl Compounds; Collagen; Disease Models, Animal; Fibrosis; Glucosides; Hydroxyprolin | 2021 |
Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat.
Topics: Adiposity; Animals; Antipsychotic Agents; Cardiomegaly; Disease Models, Animal; Female; Haloperidol; | 2021 |
Reduction of Abdominal Adhesions with Elecrospun Fiber Membranes in Rat Models.
Topics: Animals; Cecum; Chitosan; Disease Models, Animal; Fibrosis; Humans; Hydroxybutyrates; Hydroxyproline | 2018 |
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedge | 2017 |
Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans.
Topics: Actins; Animals; Antioxidants; Bile Ducts; Caffeine; Coffee; Connective Tissue Growth Factor; Diseas | 2017 |
Total flavonoids of Desmodium styracifolium attenuates the formation of hydroxy-L-proline-induced calcium oxalate urolithiasis in rats.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Fabaceae; Flavonoids; Humans; Hydroxyproline; Kidn | 2018 |
Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination | 2018 |
Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Burns; Chromones; Diptera; Disease Models, | 2017 |
Effects of vacuum sealing drainage on the treatment of cranial bone-exposed wounds in rabbits.
Topics: Animals; Bandages; Disease Models, Animal; Drainage; Hydroxyproline; Microvessels; Negative-Pressure | 2017 |
Enteral feeding with low-methoxyl pectin accelerates colonic anastomosis healing in rats.
Topics: Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Enteral Nutrition; Fatty Acids | 2018 |
Effect of Rifaximin on Hepatic Fibrosis in Bile Duct-ligated Rat Model.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Ducts; Bilirubin; Ch | 2017 |
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Topics: Airway Remodeling; Animals; beta Catenin; Disease Models, Animal; Female; Hydroxyproline; Interleuki | 2018 |
Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model.
Topics: Animals; Carnitine O-Palmitoyltransferase; Dietary Proteins; Dietary Sucrose; Disease Models, Animal | 2018 |
The targeted regulation of miR-26a on PTEN-PI3K/AKT signaling pathway in myocardial fibrosis after myocardial infarction.
Topics: Animals; Antagomirs; Cell Differentiation; Disease Models, Animal; Fibroblasts; Hydroxyproline; Male | 2018 |
Comparative evaluation of therapeutic efficacy of intra-articular oxaceprol with conventional modalities in osteoarthritis animal model.
Topics: Animals; Antirheumatic Agents; Arthralgia; Cartilage, Articular; Disease Models, Animal; Hydroxyprol | 2018 |
Wound healing property of milk in full thickness wound model of rabbit.
Topics: Animals; Cattle; Disease Models, Animal; Hydroxyproline; Male; Milk; Ointments; Phenytoin; Powders; | 2018 |
Thrombin and factor Xa link the coagulation system with liver fibrosis.
Topics: Actins; Animals; Antithrombins; Blood Coagulation; Cell Line; Cell Shape; Dabigatran; Disease Models | 2018 |
Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication.
Topics: Acute Lung Injury; Animals; Biomarkers; Cyclophosphamide; Cytoprotection; Disease Models, Animal; Dr | 2018 |
Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis.
Topics: Administration, Oral; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydr | 2018 |
Animal Models of Pulmonary Fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Fluorescein-5-isothiocyanate; Histocytochemistry; Hydrox | 2018 |
Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway.
Topics: ADAMTS1 Protein; Animals; Antagomirs; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Collagen | 2018 |
Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress.
Topics: Animals; Apoptosis; Colitis; Dextran Sulfate; Disease Models, Animal; Glycine; Hydroxyproline; Inter | 2018 |
Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Flow C | 2018 |
Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Coumaric Acid | 2018 |
Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.
Topics: Animals; Colitis; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Hydroxyproline; | 2018 |
A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice.
Topics: Actins; Animals; Antibiotics, Antineoplastic; Bleomycin; Bombyx; Connective Tissue Growth Factor; Di | 2018 |
Beneficial contribution of a safflower (Carthamus tinctorius L.) polysaccharide on steroid-induced avascular necrosis of the femoral head in rats.
Topics: Animals; Apoptosis; Carthamus tinctorius; Caspase 3; Disease Models, Animal; Femur Head Necrosis; He | 2019 |
Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation.
Topics: 3' Untranslated Regions; Animals; Atrial Fibrillation; Cell Proliferation; Collagen; Disease Models, | 2019 |
Epicatechin protective effects on bleomycin-induced pulmonary oxidative stress and fibrosis in mice.
Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Catalase; Catechin; Disease Models, Animal; Glutathion | 2019 |
Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Anticoagulants; Bleomycin; Dermatan Sulfate; Disease Models, A | 2019 |
Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C.
Topics: Actins; Animals; Collagen Type III; Disease Models, Animal; Fibroblasts; Hydroxyproline; Lipopolysac | 2019 |
Hyaluronic acid hydrogel loaded by adipose stem cells enhances wound healing by modulating IL-1β, TGF-β1, and bFGF in burn wound model in rat.
Topics: Acellular Dermis; Adipocytes; Animals; Burns; Disease Models, Animal; Drug Carriers; Fibroblast Grow | 2020 |
Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM.
Topics: Animals; Cardiomyopathy, Hypertrophic, Familial; Dependovirus; Disease Models, Animal; Echocardiogra | 2019 |
Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Disease Models | 2019 |
The protective and anti-inflammatory effect of methylene blue in corrosive esophageal burns: An experimental study.
Topics: Animals; Anti-Inflammatory Agents; Burns, Chemical; Caustics; Disease Models, Animal; Enzyme Inhibit | 2019 |
Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis
Topics: Actins; Animals; Benzofurans; Collagen Type I; CX3C Chemokine Receptor 1; Disease Models, Animal; Ex | 2019 |
Metformin attenuates bleomycin-induced scleroderma by regulating the balance of Treg/Teff cells and reducing spleen germinal center formation.
Topics: Animals; Bleomycin; Cell Differentiation; Collagen; Disease Models, Animal; Female; Fibrosis; Germin | 2019 |
The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model.
Topics: Administration, Oral; Anastomosis, Surgical; Animals; Disease Models, Animal; Drug Therapy, Combinat | 2013 |
Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys.
Topics: Animals; Calcium Oxalate; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Dogs; D | 2014 |
Effects of metoclopramide on healing of colonic anastomoses in a rat model of abdominal sepsis.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Hydroxyproline | 2013 |
Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21.
Topics: Actins; Administration, Oral; Animals; Antioxidants; Bleomycin; Disease Models, Animal; Dose-Respons | 2013 |
Gender-dependence of bone structure and properties in adult osteogenesis imperfecta murine model.
Topics: Animals; Biomechanical Phenomena; Carbonates; Disease Models, Animal; Elastic Modulus; Female; Hydro | 2013 |
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cu | 2013 |
Zinc as a nutritional approach to bone loss prevention in an ovariectomized rat model.
Topics: Animals; Catalase; Disease Models, Animal; Female; Glutathione; Humans; Hydroxyproline; Osteoporosis | 2013 |
Interleukin-17A plays a pivotal role in cholestatic liver fibrosis in mice.
Topics: Actins; Animals; Cells, Cultured; Collagen Type I; Disease Models, Animal; Hepatic Stellate Cells; H | 2013 |
Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6.
Topics: Alveolar Epithelial Cells; Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar La | 2013 |
Association of age-dependent liver injury and fibrosis with immune cell populations.
Topics: Age Factors; Aging; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced L | 2013 |
[Monoclonal antibody against laminin receptor 1 inhibits the pulmonary fibrosis induced by bleomycin in rats].
Topics: Animals; Antibodies, Monoclonal; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Matr | 2013 |
Inflammatory process induced by carrageenan in adjacent tissue triggers the acute inflammation in deep digital flexor tendon of rats.
Topics: Animals; Carrageenan; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Hydroxyproli | 2013 |
[Prophylactic effect of probiotic strains Bifidobacterium animalis VKL and VKB on stress-induced lesions in the gastric mucosa of rats].
Topics: Animals; Bifidobacterium; Dietary Supplements; Disease Models, Animal; Female; Food Deprivation; Fru | 2013 |
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats.
Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemica | 2013 |
Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.
Topics: Animals; Apoptosis; Bleomycin; Bronchoalveolar Lavage; Caveolin 1; Disease Models, Animal; Gene Expr | 2013 |
Mechanical and morphological aspects of the calcaneal tendon of mdx mice at 21 days of age.
Topics: Animals; Biomechanical Phenomena; Calcaneus; Disease Models, Animal; Hydroxyproline; Male; Mice; Mic | 2013 |
Dual release of dexamethasone and TGF-β3 from polymeric microspheres for stem cell matrix accumulation in a rat disc degeneration model.
Topics: Adipose Tissue; Animals; Cell Differentiation; Dexamethasone; Disease Models, Animal; Gene Expressio | 2013 |
Evaluation of in vivo wound healing activity of Bacopa monniera on different wound model in rats.
Topics: Animals; Antioxidants; Bacopa; Bacteria; Disease Models, Animal; Free Radicals; Granulation Tissue; | 2013 |
Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro.
Topics: Animals; Benzofurans; Cell Proliferation; Collagen Type I; Disease Models, Animal; Hepatic Stellate | 2013 |
Efficacy of HGF carried by ultrasound microbubble-cationic nano-liposomes complex for treating hepatic fibrosis in a bile duct ligation rat model, and its relationship with the diffusion-weighted MRI parameters.
Topics: Animals; Common Bile Duct; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Drug Carrie | 2013 |
Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models.
Topics: Animals; Bleomycin; Disease Models, Animal; Elasticity; Fibrosis; Hydroxyproline; Hypersensitivity; | 2013 |
Tendon tissue engineering and its role on healing of the experimentally induced large tendon defect model in rabbits: a comprehensive in vivo study.
Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; Hydroxyproline; | 2013 |
[The inhibitory effect of latent transforming growth factor β1 activation and silicosis by CD36 targeted RNA interference in silicosis model of rat].
Topics: Animals; Bronchoalveolar Lavage Fluid; CD36 Antigens; Disease Models, Animal; Female; Hydroxyproline | 2013 |
Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Cell Proliferation; Disease Models, Animal; Fibroblast | 2013 |
Using bosentan to treat paraquat poisoning-induced acute lung injury in rats.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bosentan; Disease Models, Animal; Endothelin- | 2013 |
Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.
Topics: Adoptive Transfer; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Cell Prol | 2014 |
Periostin as a modulator of chronic cardiac remodeling after myocardial infarction.
Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Collagen Type I; Collagen Type III; Diastole; D | 2013 |
Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model.
Topics: Animal Feed; Animals; Calcium Oxalate; Diet; Disease Models, Animal; Female; Hydroxyproline; Hyperox | 2013 |
CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis.
Topics: Actins; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; CCN Intercellular Signaling Proteins; Cell | 2014 |
Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; fas Receptor; Hydroxyproline; Idiopathi | 2014 |
Wound healing activity of the inflorescence of Typha elephantina (Cattail).
Topics: Administration, Topical; Animals; Bandages; Disease Models, Animal; Female; Free Radical Scavengers; | 2014 |
The use of collagen content as determined by spectral domain polarization-sensitive optical coherence tomography to assess colon anastomosis healing in a rat model.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Antineoplastic Agents; Collagen; Collagen Type I; | 2014 |
Agmatine attenuates silica-induced pulmonary fibrosis.
Topics: Agmatine; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytoprotection; Disease Models, Animal; | 2014 |
[Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice].
Topics: Actins; Animals; Bleomycin; Calcitriol; Collagen Type I; Disease Models, Animal; Gene Expression Reg | 2013 |
Protection of colonic anastomosis with platelet-rich plasma gel in the open abdomen.
Topics: Abdomen; Abdominal Wound Closure Techniques; Anastomosis, Surgical; Animals; Colon; Disease Models, | 2014 |
The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions.
Topics: Anastomosis, Surgical; Animals; Body Weight; Collagenases; Colon; Disease Models, Animal; Hydroxypro | 2014 |
Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.
Topics: Animals; Biomechanical Phenomena; Collagen; Diaphragm; Disease Models, Animal; Elasticity; Extracell | 2014 |
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.
Topics: Acetophenones; Animals; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hyperoxal | 2014 |
The optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Disease Models, Animal; Femur; Hydroxyprol | 2014 |
Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
Topics: Animals; Bleomycin; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Inflammation; Lung | 2014 |
Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation.
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Hydroxyproline; Lactoferrin; Live | 2014 |
The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factors; Extracellular Matrix Proteins; Femal | 2014 |
Electrical impedance myography for the in vivo and ex vivo assessment of muscular dystrophy (mdx) mouse muscle.
Topics: Age Factors; Animals; Biomarkers; Disease Models, Animal; Electric Impedance; Electromyography; Hydr | 2014 |
Effect of nilotinib on airway remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Chronic Disease; Disease Models, Animal; Female; Hydroxy | 2014 |
Topical vitamin D analogue calcipotriol reduces skin fibrosis in experimental scleroderma.
Topics: Administration, Topical; Animals; Bleomycin; Calcitriol; Collagen; Cytokines; Dermatologic Agents; D | 2014 |
Fibrogenesis in granulomas and lung interstitium in tuberculous inflammation in mice.
Topics: Animals; BCG Vaccine; Cell Proliferation; Disease Models, Animal; Fibroblasts; Granuloma; Hydroxypro | 2014 |
Silencing histone deacetylase 2 using small hairpin RNA induces regression of fibrotic plaque in a rat model of Peyronie's disease.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Histone Deacetylase 2; Humans; Hydroxyp | 2014 |
Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia.
Topics: Animals; Apoptosis; Butylated Hydroxytoluene; Cell Proliferation; Collagen Type I; Collagen Type II; | 2014 |
Ultrapure alginate anti-adhesion gel does not impair colon anastomotic strength.
Topics: Abdominal Abscess; Alginates; Anastomosis, Surgical; Animals; Biocompatible Materials; Collagen; Col | 2014 |
Therapeutic potential of amniotic-fluid-derived stem cells on liver fibrosis model in mice.
Topics: Alanine Transaminase; Amniotic Fluid; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Di | 2014 |
Immunomodulatory effectiveness of licofelone in preventing epidural fibrosis in post-laminectomy rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cicatrix; Disease Models, Animal; Double-Blind Met | 2015 |
Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Collagen Type I; Disease Models, Animal; Drugs, Chine | 2014 |
Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament Reconstruction; Asparagine; Biomarkers; Disease Models, Animal; | 2015 |
Resolution of chronic bacterial-induced prostatic inflammation reverses established fibrosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Chromatography, High Pressure Liquid; Collagen; Dise | 2015 |
Chunggan extract, a traditional herbal formula, ameliorated alcohol-induced hepatic injury in rat model.
Topics: Animals; Cell Line; Collagen; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Dr | 2014 |
IL-21 induction of CD4+ T cell differentiation into Th17 cells contributes to bleomycin-induced fibrosis in mice.
Topics: Animals; Bleomycin; CD4-Positive T-Lymphocytes; Cell Differentiation; Disease Models, Animal; Female | 2015 |
Effect of intraperitoneal curcumin instillation on postoperative peritoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Curcumin; Disease Models, Animal; Hydroxypr | 2015 |
Role of Fn14 in acute alcoholic steatohepatitis in mice.
Topics: Acute Disease; Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; | 2015 |
High vitamin D and calcium intakes increase bone mineral (Ca and P) content in high-fat diet-induced obese mice.
Topics: Animals; Bone and Bones; Calcium; Calcium, Dietary; Cholecalciferol; Diet, High-Fat; Disease Models, | 2015 |
Preventive effects of ¹²⁵I seeds on benign restenosis following esophageal stent implantation in a dog model.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Disease Models, Animal; Dogs; Esophageal Stenosi | 2015 |
Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.
Topics: Animals; Bleomycin; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Disease Model | 2016 |
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis.
Topics: Actins; Animals; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Dioxoles; Disease Models, | 2015 |
Assessment of aged mdx mice by electrical impedance myography and magnetic resonance imaging.
Topics: Animals; Disease Models, Animal; Electric Impedance; Hydroxyproline; Magnetic Resonance Imaging; Mal | 2015 |
Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Actins; Animals; Bleomycin; Collagen Type I; Disease Models, Animal; Drugs, Chinese Herbal; Female; | 2015 |
Effect of novel curcumin-encapsulated chitosan-bioglass drug on bone and skin repair after gamma radiation: experimental study on a Wistar rat model.
Topics: Animals; Bone and Bones; Ceramics; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Female | 2015 |
Amelioration of bleomycin-induced pulmonary fibrosis in a mouse model by a combination therapy of bosentan and imatinib.
Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Bosentan; Catalase; Collagen Type I; Collagen | 2015 |
Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.
Topics: Animals; Bleomycin; Cell Count; Chemokine CCL3; Collagen Type I; Connective Tissue Growth Factor; Di | 2015 |
Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen; Cytokines; Cytoprotection | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Couma | 2015 |
Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; | 2015 |
Effect of transplanted adipose‑derived stem cells in mice exhibiting idiopathic pulmonary fibrosis.
Topics: Adipose Tissue; Alveolar Epithelial Cells; Animals; Apoptosis; Biomarkers; Bronchoalveolar Lavage Fl | 2015 |
The Effect of Systemic Carnitine Administration on Colon Anastomosis Healing in an Experimental Sepsis Model.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Carnitine; Colon; Disease Models, Animal; Hydroxyproli | 2015 |
An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Disease Models, Animal; Endostati | 2015 |
Role of thioredoxin nitration in bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; L | 2016 |
Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Epithelial Cells; Gene Expression Profiling; Humans; Hyd | 2015 |
Effect of roflumilast on airway remodelling in a murine model of chronic asthma.
Topics: Airway Remodeling; Allergens; Aminopyridines; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Br | 2016 |
Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Collectins; Cytokines; Disease Models, A | 2015 |
Partial deletion of the ROCK2 protein fails to reduce renal fibrosis in a unilateral ureteral obstruction model in mice.
Topics: Animals; Collagen Type I; Disease Models, Animal; Fibrosis; Gene Deletion; Heterozygote; Hydroxyprol | 2016 |
[Effect of edaravone on oxidative stress and myocardial fibrosis induced by isoproterenol in rats].
Topics: Animals; Antipyrine; Cardiomyopathies; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Edar | 2015 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleu | 2015 |
Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Disease Models, Animal; Hydroxyproline; Hyperoxaluria, Primary; Li | 2016 |
Muscle damage, metabolism, and oxidative stress in mdx mice: Impact of aerobic running.
Topics: Animals; Collagen; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Glutathione | 2016 |
Mechanical Bowel Preparation Does Not Affect Anastomosis Healing in an Experimental Rat Model.
Topics: Anastomosis, Surgical; Animals; Cathartics; Colectomy; Colon; Disease Models, Animal; Hydroxyproline | 2016 |
Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction.
Topics: Animals; Collagen; Diabetes Mellitus; Disease Models, Animal; Drug Delivery Systems; Erectile Dysfun | 2016 |
The Effect of Platelet-Rich-Plasma on the Healing of Left Colonic Anastomosis in a Rat Model of Intra-Abdominal Sepsis.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Growth Substances; Hydroxyproline; Ma | 2016 |
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats | 2017 |
Inhibition by all-trans retinoic acid of collagen degradation mediated by corneal fibroblasts.
Topics: Animals; Cells, Cultured; Collagen; Corneal Keratocytes; Corneal Ulcer; Disease Models, Animal; Dose | 2016 |
Postoperative anti-adhesion ability of a novel carboxymethyl chitosan from silkworm pupa in a rat cecal abrasion model.
Topics: Animals; Bombyx; Cecum; Chitosan; Cytokines; Disease Models, Animal; Hydroxyproline; Leukocytes; Mal | 2016 |
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Topics: Animals; Blood Pressure; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Endomyocardial Fib | 2016 |
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats.
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Cros | 2016 |
In Vivo Wound Healing Studies.
Topics: Administration, Cutaneous; Animals; Biomarkers; Bioprospecting; Disease Models, Animal; Drug Discove | 2016 |
Effects of chitin and sepia ink hybrid sponge on the healing of burning wound rats and its impact on macrophages in vitro.
Topics: Animals; Burns, Chemical; Chitin; Cytokines; Disease Models, Animal; Hydroxyproline; Ink; Macrophage | 2016 |
Increased fibrosis and impaired intratumoral accumulation of macromolecules in a murine model of pancreatic cancer co-administered with FGF-2.
Topics: Albumin-Bound Paclitaxel; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Line, T | 2016 |
Anti-osteoarthritic activity of Bungarus fasciatus venom fraction BF-F47 involving molecular markers in the rats.
Topics: Animals; Biological Products; Biomarkers; Bone Density Conservation Agents; Bungarus; Chromatography | 2016 |
Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung.
Topics: Actins; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Connecti | 2016 |
Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9.
Topics: Amides; Animals; Antioxidants; Biomarkers; Bleomycin; Cytoprotection; Disease Models, Animal; Dose-R | 2016 |
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.
Topics: Actins; Animals; Collagen; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fatty Acids, O | 2016 |
HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.
Topics: Animals; Bile Ducts; Disease Models, Animal; Humans; Hydroxyproline; Hypoxia-Inducible Factor 1, alp | 2017 |
Effect of Topical Platelet-Rich Plasma on Burn Healing After Partial-Thickness Burn Injury.
Topics: Animals; Burns; Disease Models, Animal; Hydroxyproline; Male; Platelet-Rich Plasma; Random Allocatio | 2016 |
Traditional Chinese Medicine Formula "Xiaofeng granules" suppressed gouty arthritis animal models and inhibited the proteoglycan degradation on chondrocytes induced by monosodium urate.
Topics: ADAMTS4 Protein; Animals; Arthritis, Gouty; Cells, Cultured; Chondrocytes; Cytokines; Disease Models | 2016 |
Metabolomics study of renal fibrosis and intervention effects of total aglycone extracts of Scutellaria baicalensis in unilateral ureteral obstruction rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Discr | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, T | 2016 |
Evaluation of potent phytomedicine for treatment of psoriasis using UV radiation induced psoriasis in rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Dermatologic Agents; Disease Models, Anima | 2016 |
Automated evaluation of liver fibrosis in thioacetamide, carbon tetrachloride, and bile duct ligation rodent models using second-harmonic generation/two-photon excited fluorescence microscopy.
Topics: Animals; Automation, Laboratory; Bile Ducts; Carbon Tetrachloride; Disease Models, Animal; Hydroxypr | 2017 |
Antifibrotic Effects of Carvedilol and Impact of Liver Fibrosis on Carvedilol Pharmacokinetics in a Rat model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers; Carbazoles; Carvedilol | 2017 |
Optimized Mouse Models for Liver Fibrosis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; | 2017 |
Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Chitosan; Disease Models, Animal; Ethanol; Gastric Mucosa; | 2016 |
Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Disease Progression; Hydroxyproline; Imaging, Three-Dimensional; Ma | 2017 |
Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation.
Topics: Actins; Animals; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Chemokine CCL2; Collag | 2017 |
Effect of thalidomide on the healing of colonic anastomosis, in rats.
Topics: Anastomosis, Surgical; Angiogenesis Inhibitors; Animals; Biomarkers; Collagen; Colon; Disease Models | 2008 |
Effects of preoperative pelvic irradiation on colonic anastomosis healing. An experimental study in rats.
Topics: Anastomosis, Surgical; Animals; Collagen; Colon; Disease Models, Animal; Hydroxyproline; Male; Matri | 2008 |
A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Lung; Male; Malondialdehyde; Oxidativ | 2008 |
A TSP-1 synthetic peptide inhibits bleomycin-induced lung fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; I | 2009 |
Attenuation effects of heparin-superoxide dismutase conjugate on bleomycin-induced lung fibrosis in vivo and radiation-induced inflammatory cytokine expression in vitro.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression; Heparin; | 2009 |
The effects of intraperitoneal sildenafil administration on healing of left colonic anastomoses and intra-abdominal adhesion formation in the presence of intra-abdominal infection.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Injections, Intraperi | 2008 |
Platelets contribute to the reduction of liver fibrosis in mice.
Topics: Animals; Blood Platelets; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Female; | 2009 |
Development of hepatorenal syndrome in bile duct ligated rats.
Topics: Animals; Bile Ducts; Creatinine; Disease Models, Animal; Disease Progression; Hepatorenal Syndrome; | 2008 |
The effects of adjuvant experimental radioimmunotherapy and hyperthermic intraperitoneal chemotherapy on intestinal and abdominal healing after cytoreductive surgery for peritoneal carcinomatosis in the rat.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, R | 2008 |
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression; Hydroxyproline; Immunoglobulin | 2009 |
Wound healing properties of Carica papaya latex: in vivo evaluation in mice burn model.
Topics: Animals; Burns; Carica; Chlorhexidine; Disease Models, Animal; Dose-Response Relationship, Drug; Epi | 2009 |
Effects of the amniotic membrane on healing of colonic anastomoses in experimental left-sided colonic obstruction.
Topics: Amnion; Anastomosis, Surgical; Animals; Colonic Diseases; Disease Models, Animal; Female; Humans; Hy | 2010 |
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; C | 2009 |
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Topics: Administration, Inhalation; Animals; Asthma; Base Sequence; Bronchoalveolar Lavage Fluid; Cells, Cul | 2009 |
[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibr | 2008 |
Treatment of chronic proliferative cholangitis with c-myc shRNA.
Topics: Animals; Cholangitis; Collagen Type III; Disease Models, Animal; Gallstones; Genes, myc; Glucuronida | 2009 |
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Mo | 2009 |
Effects of amniotic membrane on the healing of primary colonic anastomoses in the cecal ligation and puncture model of secondary peritonitis in rats.
Topics: Amnion; Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Female; Humans; Hydrox | 2009 |
[Function of type I repetitive consequence peptide segment of thrombospondin-1 in inhibition of fibrosis of mice].
Topics: Animals; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Lung; Mice; Thrombospondin 1 | 2009 |
K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function.
Topics: Animals; Aorta, Abdominal; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Agents; Disease | 2009 |
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Bone Marrow Cells; Chondrocytes; | 2009 |
Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Live | 2009 |
The effect of cyanoacrylate in esophagocutaneous leakages occurring after esophageal anastomosis.
Topics: Anastomosis, Surgical; Animals; Cutaneous Fistula; Cyanoacrylates; Disease Models, Animal; Esophagea | 2009 |
Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Bronch | 2009 |
Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.
Topics: Animals; Animals, Congenic; Calcium Oxalate; Chromosomes, Mammalian; Disease Models, Animal; Genetic | 2009 |
Estrogen deficiency and tobacco smoke exposure promote matrix metalloproteinase-13 activation in skin of aging B6 mice.
Topics: Animals; Disease Models, Animal; Enzyme Activation; Estradiol; Estrogens; Female; Hydroxyproline; Ma | 2009 |
Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice.
Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Hydroxy | 2010 |
Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis.
Topics: Animals; Bleomycin; Body Weight; Cell Survival; Cells, Cultured; Citrus; Disease Models, Animal; Dru | 2009 |
Anti-fibrotic effects of a methylenedioxybenzene compound, CW209292 on dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Benzodioxoles; Body Weight; Cell Proliferation; Dimethylnitrosamine; Disease Models, Animal | 2009 |
Simvastatin attenuates experimental small airway remodelling in rats.
Topics: Airway Remodeling; Animals; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydr | 2009 |
Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats.
Topics: Animals; Atorvastatin; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoi | 2010 |
Melatonin prevents peritoneal adhesions in rats.
Topics: Administration, Oral; Animals; Antioxidants; Cecum; Disease Models, Animal; Hydroxyproline; Male; Ma | 2009 |
Effect of Laggera alata on hepatocyte damage induced by carbon tetrachloride in vitro and in vivo.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Asteraceae; Blood Proteins; Carbon Tetra | 2009 |
Fluid regimen for intestinal anastomosis.
Topics: Anastomosis, Surgical; Animals; Crystalloid Solutions; Disease Models, Animal; Fluid Therapy; Hydrox | 2009 |
Rolipram attenuates bleomycin A5-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytokines; Disease Mod | 2009 |
Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid | 2009 |
Cardiac fibrosis and diastolic dysfunction after myocardial infarction in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; Body Weight; Diastole; Disease Models, Animal; Echocardiography, Doppler | 2009 |
Effect of antler extract on corticosteroid-induced avascular necrosis of the femoral head in rats.
Topics: Animals; Animals, Newborn; Antlers; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cul | 2010 |
Emodin protects rat liver from CCl(4)-induced fibrogenesis via inhibition of hepatic stellate cells activation.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Disease Models, An | 2009 |
Extracorporeal photopheresis in a rat model of pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation | 2009 |
Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line; Cell Proliferation; Collagen | 2009 |
Pulmonary fibrosis induced by H5N1 viral infection in mice.
Topics: Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Influenza A Virus, H5N1 S | 2009 |
Prevention of osteoporosis in mice after ovariectomy via allograft of microencapsulated ovarian cells.
Topics: Alginates; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Bone and Bones; Bone Remodeling; | 2010 |
[The effect of urokinase on hepatic fibrogenesis in rats].
Topics: Actins; Animals; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver | 2009 |
Effect of isoflavone-enriched milk on bone mass in ovariectomized rats.
Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Disease Models, Animal; Female; Hydroxypro | 2009 |
A CD36 synthetic peptide inhibits silica-induced lung fibrosis in the mice.
Topics: Animals; CD36 Antigens; Collagen Type I; Collagen Type III; Disease Models, Animal; Female; Fibrosis | 2010 |
Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model.
Topics: Acids; Animals; Diet; Disease Models, Animal; Female; Glycolates; Hydrogen-Ion Concentration; Hydrox | 2010 |
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Respo | 2010 |
Evaluation of a new type of wound dressing made from recombinant spider silk protein using rat models.
Topics: Animals; Biological Dressings; Burns; Collagen; Disease Models, Animal; Fibroblast Growth Factor 2; | 2010 |
[Therapeutic effect of Haobieyangyinruanjianfang on the mouse liver fibrosis caused by schistosomiasis].
Topics: Animals; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyaluronic Acid; | 2010 |
The changes in various hydroxyproline fractions in aortic tissue of rabbits are closely related to the progression of atherosclerosis.
Topics: Animals; Aorta; Atherosclerosis; Cholesterol; Cholesterol, LDL; Collagen; Dietary Fats; Disease Mode | 2010 |
A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Bleomycin; Bronchoalveolar Lavage Fluid; Cytoki | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation | 2010 |
Effects of Haobie Yangyin Ruanjian decoction on hepatic fibrosis induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Blotting, Western; Carbon Te | 2010 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, | 2010 |
Effectiveness of topical zinc oxide application on hypertrophic scar development in rabbits.
Topics: Administration, Topical; Animals; Cicatrix, Hypertrophic; Dermatologic Agents; Disease Models, Anima | 2010 |
Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Chronic Disease; Coll | 2010 |
N-acetyl cysteine promotes angiogenesis and clearance of free oxygen radicals, thus improving wound healing in an alloxan-induced diabetic mouse model of incisional wound.
Topics: Acetylcysteine; Alloxan; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Free Radi | 2010 |
Functional and structural changes in end-stage kidney disease due to glomerulonephritis induced by the recombinant alpha3(IV)NC1 domain.
Topics: Actins; Animals; Autoantigens; Collagen Type I; Collagen Type IV; Creatinine; Disease Models, Animal | 2010 |
Mizoribine protects against bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Prol | 2010 |
Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Disease Prog | 2010 |
Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and Schistosomal infection in mice.
Topics: Animals; Bilirubin; Biomarkers; Biopsy; Collagen; Disease Models, Animal; Ethanol; gamma-Glutamyltra | 2010 |
Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylene Glycol; | 2010 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fib | 2010 |
Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bleomycin; Blotting, Western; Bronchoalveolar | 2010 |
A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzamides; Collagen; Collagen Type I; Collagen Ty | 2010 |
Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride- and ethanol-induced hepatic damage.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotra | 2010 |
Experimental induction of calcium oxalate nephrolithiasis in mice.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Glyoxylates; Hydroxyproli | 2010 |
The effect of sealing with a fixed combination of collagen matrix-bound coagulation factors on the healing of colonic anastomoses in experimental high-risk mice models.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Collagen; Collagen Type I; Collagen Type III; Colo | 2010 |
Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury.
Topics: Amides; Animals; Caustics; Collagen; Disease Models, Animal; Enzyme Inhibitors; Esophageal Stenosis; | 2011 |
Mandibular bone density and calcium content affected by different kind of stress in mice.
Topics: Adrenal Glands; Animals; Bone Density; Calcium; Disease Models, Animal; Electroshock; Hydrocortisone | 2010 |
The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension.
Topics: Animals; Biomechanical Phenomena; Blood Pressure; Chronic Disease; Collagen Type I; Collagen Type I, | 2010 |
Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Collagen Type I | 2009 |
Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.
Topics: Animals; Apoptosis; Blood Cell Count; Bone Marrow; Cell Survival; Cells, Cultured; Disease Models, A | 2010 |
A natural process of cirrhosis resolution and deceleration of liver regeneration after thioacetamide withdrawal in a rat model.
Topics: Animals; Body Weight; Collagen; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Interc | 2011 |
Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis.
Topics: Animals; Benzofurans; Caffeic Acids; Collagen Type III; Connective Tissue Growth Factor; Disease Mod | 2011 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, A | 2010 |
Improved methodology to induce hyperoxaluria without treatment using hydroxyproline.
Topics: Animals; Crystallization; Disease Models, Animal; Hydroxyproline; Hyperoxaluria; Kidney; Male; Oxali | 2011 |
Plantarflexion contracture in the mdx mouse.
Topics: Animals; Collagen; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Mice; Mice, Inbred mdx; M | 2010 |
Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect.
Topics: Animals; Diastole; Disease Models, Animal; Female; Heart Failure; Hydroxymethylglutaryl-CoA Reductas | 2011 |
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Biomechanical Phenomena; Body Weight; Disease Mod | 2011 |
Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis.
Topics: Aging; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Drosophila melanogaster; E | 2011 |
Wound healing and antimicrobial potential of Carissa spinarum Linn. in albino mice.
Topics: Animals; Anti-Infective Agents; Apocynaceae; Burns; Collagen; Disease Models, Animal; Epithelium; Fe | 2011 |
A novel method for accurate collagen and biochemical assessment of pulmonary tissue utilizing one animal.
Topics: Analysis of Variance; Animals; Asbestos, Crocidolite; Asbestosis; Azo Compounds; Biomarkers; Collage | 2011 |
Effects and mechanisms of Acremoniumterricola milleretal mycelium on liver fibrosis induced by carbon tetrachloride in rats.
Topics: Acremonium; Animals; Antioxidants; Biological Products; Carbon Tetrachloride; Disease Models, Animal | 2011 |
Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.
Topics: Animals; Biomarkers; Blotting, Western; Cell Proliferation; Disease Models, Animal; Ethanol; Fatty L | 2011 |
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Humans; Hydroxyp | 2011 |
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap | 2011 |
The effect of alpha-lipoic acid in the prevention of peritoneal adhesions.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Male; Malondialdehyde; Oxidative Stre | 2011 |
Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model.
Topics: Administration, Topical; Amines; Animals; Bacitracin; Benzopyrans; Disease Models, Animal; Dose-Resp | 2011 |
Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Alkanes; Animals; Biomarkers; Bone Diseases, Metabolic; Bone | 2011 |
Dietary induction of long-term hyperoxaluria in the porcine model.
Topics: Animals; Catheterization; Diet; Disease Models, Animal; Gelatin; Hydroxyproline; Hyperoxaluria; Oxal | 2012 |
Comparison of antioxidative and antifibrotic effects of α-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis.
Topics: Actins; Administration, Oral; alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Apo | 2011 |
Assessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Body Temperature; Body Weight; Disease Models, Anim | 2012 |
Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis.
Topics: Animals; Annexin A1; Biomimetic Materials; Bleomycin; Cytokines; Disease Models, Animal; Epithelial | 2011 |
Hepatoprotective activity of a phytotherapeutic formula on thioacetamide--induced liver fibrosis model.
Topics: Animals; Disease Models, Animal; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Liver; | 2011 |
Healing promoting potentials of roots of Ficus benghalensis L. in albino rats.
Topics: Animals; Disease Models, Animal; Female; Ficus; Granulation Tissue; Hydroxyproline; Male; Phytothera | 2011 |
Puerarin prevents isoprenaline-induced myocardial fibrosis in mice by reduction of myocardial TGF-β1 expression.
Topics: Animals; Biological Products; Cardiomyopathies; Cardiotonic Agents; Collagen; Disease Models, Animal | 2012 |
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Disease Mod | 2012 |
Effects of acute inflammation induced in the rat paw on the deep digital flexor tendon.
Topics: Acute Disease; Animals; Carrageenan; Disease Models, Animal; Edema; Electrophoresis, Agar Gel; Extra | 2012 |
Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study.
Topics: Acetic Acid; Animals; Anti-Infective Agents; Capillary Permeability; Disease Models, Animal; Hydroxy | 2012 |
Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Animal; Enzy | 2012 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2012 |
Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Humanized; Bleomycin; Cytokines; Dacli | 2012 |
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Body W | 2012 |
Exercise training post-MI favorably modifies heart extracellular matrix in the rat.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Collagen; Disease Models, Anima | 2012 |
The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; CD4-Positive T-Lymphocytes; Cell Count; Disease Mod | 2012 |
[Protective effects of Leonurus japonicas on myocardial remodeling induced by isoproterenol in rats].
Topics: Animals; Antioxidants; Collagen; Disease Models, Animal; Hemodynamics; Hydroxyproline; Immunohistoch | 2011 |
Antifibrotic effects of Artemisia capillaris and Artemisia iwayomogi in a carbon tetrachloride-induced chronic hepatic fibrosis animal model.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Artemisia; Carbon Tetrachloride; Chemical and Drug Indu | 2012 |
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cell Proliferation; Disease Models, Animal; Female; | 2012 |
Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice.
Topics: Amylases; Animals; Ceruletide; Collagen; Disease Models, Animal; Fibrosis; Humans; Hydroxyproline; I | 2012 |
Ethyl pyruvate improves healing of colonic anastomosis in a rat model of peritonitis.
Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; | 2012 |
A high molecular weight protein extract of Mastobranchus indicus (Mi-64) having antiarthritic activity in experimental animals.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Ankle Joint; Anti-Inflammatory Agents, Non-Steroida | 2012 |
Effects of low-level laser therapy (GaAs) in an animal model of muscular damage induced by trauma.
Topics: Animals; Antioxidants; Cell Respiration; Collagen; Creatine Kinase; Disease Models, Animal; Hydroxyp | 2013 |
A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.
Topics: Analysis of Variance; Animals; Apoptosis; Carrier Proteins; Cell Differentiation; Cells, Cultured; C | 2012 |
UVA irradiation following treatment with topical 8-methoxypsoralen improves bleomycin-induced scleroderma in a mouse model, by reducing the collagen content and collagen gene expression levels in the skin.
Topics: Administration, Cutaneous; Animals; Bleomycin; Collagen Type I; Collagen Type III; Disease Models, A | 2012 |
Metabolic regulatory and anti-oxidative effects of modified Bushen Huoxue decoction on experimental rabbit model of osteoarthritis.
Topics: Animals; Antioxidants; Cartilage, Articular; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyp | 2013 |
A rat model of smoke inhalation injury.
Topics: Air Pollutants; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Capillary Permeability; C | 2012 |
Molecular MR imaging of liver fibrosis: a feasibility study using rat and mouse models.
Topics: Animals; Carbon Tetrachloride; Collagen Type I; Contrast Media; Diethylnitrosamine; Disease Models, | 2012 |
Sutureless primary repair of colonic perforation with a degradable stent in a porcine model of fecal peritonitis.
Topics: Albumins; Animals; Biocompatible Materials; Collagen; Colon; Disease Models, Animal; Feces; Female; | 2012 |
Protective effect of recombinant protein SOD-TAT on radiation-induced lung injury in mice.
Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Humans; Hydroxyproline; Lung Injury; Mic | 2012 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibr | 2012 |
Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiovascular Agents; Collagen Type I; Collagen Type III; Disease Models, | 2012 |
The therapeutic efficacy of Ulinastatin for rats with smoking inhalation injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen Type I; | 2012 |
Pomalidomide is effective for prevention and treatment of experimental skin fibrosis.
Topics: Animals; Disease Models, Animal; Fibrosis; Hydroxyproline; Immunosuppressive Agents; Mice; Mice, Inb | 2012 |
Effects of caffeic acid phenethyl ester on anastomotic healing in secondary peritonitis.
Topics: Anastomosis, Surgical; Animals; Caffeic Acids; Colon; Disease Models, Animal; Glutathione; Hydroxypr | 2012 |
[Corbrin shugan capsule for treatment of alcoholic hepatic fibrosis in rats].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Laminin; Liver; Liver Cirrho | 2012 |
Transgenic mouse model with deficient mitochondrial polymerase exhibits reduced state IV respiration and enhanced cardiac fibrosis.
Topics: Analysis of Variance; Animals; Crosses, Genetic; Disease Models, Animal; DNA Polymerase gamma; DNA P | 2013 |
LLLT improves tendon healing through increase of MMP activity and collagen synthesis.
Topics: Achilles Tendon; Animals; Collagen; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydr | 2013 |
Altered microRNAs expression profiling in experimental silicosis rats.
Topics: Animals; Ceruloplasmin; Disease Models, Animal; Hydroxyproline; Lung; Male; Microarray Analysis; Mic | 2012 |
Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice.
Topics: Age Factors; Animals; Biomechanical Phenomena; Body Weight; Disease Models, Animal; Dystrophin; Elas | 2013 |
A marginal level of dystrophin partially ameliorates hindlimb muscle passive mechanical properties in dystrophin-null mice.
Topics: Age Factors; Animals; Disease Models, Animal; Dystrophin; Gene Expression Regulation; Hydroxyproline | 2012 |
Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2.
Topics: Administration, Intravenous; Animals; Bleomycin; Body Weight; Dinoprostone; Disease Models, Animal; | 2013 |
Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzoates; Bridged-Ring Compounds; | 2012 |
Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorben | 2002 |
Renal interstitial fibrosis (RIF): II. Ultrasound follow up study of single uranyl nitrate administration causing renal dysfunction in rats--comparison with histologic and functional renal parameters.
Topics: Acute Disease; Animals; Creatinine; Disease Models, Animal; Female; Fibrosis; Follow-Up Studies; Glu | 2002 |
Sustained release of cis-hydroxyproline in the treatment of experimental proliferative vitreoretinopathy in rabbits.
Topics: Absorbable Implants; Animals; Biocompatible Materials; Chromatography, High Pressure Liquid; Delayed | 2002 |
Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Guanidines; Hy | 2002 |
Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL8; Chemokine CXCL2; Desmosine; Disease Models, A | 2002 |
Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure.
Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Collagen; Cyclodextrins; Disease Models, Anim | 2002 |
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats.
Topics: Animals; Arterioles; Collagen; Coronary Vessels; Diastole; Disease Models, Animal; Food, Formulated; | 2002 |
An investigation on skin wound healing in mice with a taurine-chitosan gel formulation.
Topics: Animals; Antioxidants; Biocompatible Materials; Chemistry, Pharmaceutical; Chitin; Chitosan; Collage | 2002 |
[The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis].
Topics: Animals; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Collagen; Disease Models, Animal; Hydroxypr | 2002 |
Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Mode | 2002 |
Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Body Weight; Ceruloplasmin; Disea | 2003 |
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats.
Topics: Acetonitriles; Acetylcysteine; Animals; Antioxidants; Biomarkers; Bleomycin; Bronchoalveolar Lavage | 2003 |
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Cytokines; Disease Model | 2003 |
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2003 |
Effect of Holotrichia diomphalia larvae on liver fibrosis and hepatotoxicity in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 2003 |
An HSV-TK transgenic mouse model to evaluate elimination of fibroblasts for fibrosis therapy.
Topics: Animals; Antiviral Agents; Apoptosis; Cells, Cultured; Collagen Type I; Disease Models, Animal; Fibr | 2003 |
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease | 2003 |
Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis.
Topics: Animals; Apoptosis; Base Sequence; Biomarkers; Blotting, Northern; Collagenases; Disease Models, Ani | 2003 |
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine.
Topics: Administration, Oral; Alanine Transaminase; Alcohol Deterrents; Animals; Bilirubin; Cholestasis, Ext | 2003 |
The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis.
Topics: Animals; Base Sequence; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2003 |
Increase in tartrate-resistant acid phosphatase of bone at the early stage of ascorbic acid deficiency in the ascorbate-requiring Osteogenic Disorder Shionogi (ODS) rat.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Ascorbic Acid Deficiency; Body Weight; Bone Resorpt | 2003 |
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Extracell | 2003 |
Follow-up study of morphology and cardiac function in rats undergoing induction of supravalvular aortic stenosis.
Topics: Analysis of Variance; Animals; Aortic Stenosis, Supravalvular; Disease Models, Animal; Echocardiogra | 2003 |
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Topics: Actins; Allergens; Animals; Antibodies; Asthma; Bronchi; Chemotaxis, Leukocyte; Collagen; Disease Mo | 2004 |
A model of chronic heart failure in spontaneous hypertensive rats (SHR).
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Hydroxyproline; H | 2004 |
A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis.
Topics: Animals; Antioxidants; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, D | 2004 |
Transforming growth factor beta1-induced glomerulopathy is prevented by 17beta-estradiol supplementation.
Topics: Animals; Basement Membrane; Disease Models, Animal; Estradiol; Extracellular Matrix; Female; Gene Ex | 2004 |
Sequential changes in redox status and nitric oxide synthases expression in the liver after bile duct ligation.
Topics: Animals; Bile Ducts, Extrahepatic; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydrox | 2004 |
Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression.
Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Collagenases; Disease Models, Animal; DNA; Dose-R | 2004 |
A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling.
Topics: Animals; Burns, Chemical; Caustics; Collagen; Contrast Media; Disease Models, Animal; Esophageal Ste | 2004 |
Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles.
Topics: Air Pollutants; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Dr | 2004 |
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cells, Cultured; Collagen; Connective Tissue Growth F | 2004 |
Animal models of scleroderma.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Disease Models, Animal; Flow Cytometry; Graft vs Ho | 2004 |
Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Bleomycin; Disease Models, Animal; HSP70 Heat-Shock P | 2004 |
[Effects of Fuzheng Huayu recipe on renal toxic interstitial fibrosis in rats].
Topics: Animals; Creatinine; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Fibrosis; H | 2004 |
The effects of castration and testosterone administration on mast cells and hydroxyproline in rat skin.
Topics: Animals; Castration; Cells, Cultured; Disease Models, Animal; Female; Hydroxyproline; Japan; Male; M | 1977 |
C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
Topics: Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked | 2004 |
Antifibrotic effect of interferon gamma in silicosis model of rat.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Immunohistochemistry; Interferon-gamma; Int | 2005 |
Effect of Ganoderma tsugae on chronically carbon tetrachloride-intoxicated rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Disease | 2004 |
Mitomycin C prevents strictures in caustic esophageal burns in rats.
Topics: Alkalies; Animals; Antibiotics, Antineoplastic; Body Weight; Burns, Chemical; Disease Models, Animal | 2005 |
Combination of interferon-beta and angiotensin-converting enzyme inhibitor, perindopril, attenuates the murine liver fibrosis development.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Antiviral Agents; Benzimidazoles; Biomark | 2005 |
Oxidative stress-mediated skin damage in an experimental mobile phone model can be prevented by melatonin.
Topics: Animals; Antioxidants; Catalase; Cell Phone; Disease Models, Animal; Fibrosis; Free Radical Scavenge | 2004 |
No detrimental effects of repeated laparotomies on early healing of experimental intestinal anastomoses.
Topics: Anastomosis, Surgical; Animals; Biomarkers; Colon; Disease Models, Animal; Hydroxyproline; Ileum; La | 2005 |
Arterialisation of the portal vein as a model for the induction of hepatic fibrosis: description of microsurgical models in the rat.
Topics: Animals; Aorta; Azo Compounds; Coloring Agents; Disease Models, Animal; Extracellular Matrix; Hydrox | 2005 |
Effect of relaxin on myocardial ischemia injury induced by isoproterenol.
Topics: Animals; Cardiomegaly; Creatine Kinase; Disease Models, Animal; Endothelins; Gene Expression; Heart; | 2005 |
Morphological signs of cirrhosis regression. Experimental observations on carbon tetrachloride-induced liver cirrhosis of rats.
Topics: Animals; Biomarkers; Biopsy; Carbon Tetrachloride; Disease Models, Animal; Female; Fluorescent Antib | 2005 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxy | 2005 |
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
Topics: Animals; Bleomycin; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Disease Models | 2005 |
Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma.
Topics: Adoptive Transfer; Animals; Bleomycin; Body Weight; Cells, Cultured; Disease Models, Animal; Hydroxy | 2005 |
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.
Topics: Animals; Apoptosis; Bleomycin; Cells; Collagen; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2005 |
Anti-monocyte chemoattractant protein 1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats.
Topics: Actins; Animals; Blotting, Western; Chemokine CCL2; Chemokines; Cytokines; Disease Models, Animal; D | 2005 |
Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproli | 2006 |
[The protective effect of recombinant Chinese interferon-gamma in pulmonary injury in mice].
Topics: Animals; Bleomycin; Collagen Type I; Collagen Type III; Disease Models, Animal; Humans; Hydroxyproli | 2005 |
Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma.
Topics: Animals; Bleomycin; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fibroblasts; Hi | 2006 |
[Does sepsis impair the healing of colonic anastomosis in splenectomized rats?].
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Pressure; Rats; Rats, | 2005 |
Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol.
Topics: Acid Phosphatase; Alkaline Phosphatase; Allyl Compounds; Animals; Bone Density; Calcium; Cholesterol | 2006 |
Combination of pre-operative radiotherapy and surgery suppresses local accumulation of collagen and TGF-beta1 in rats.
Topics: Animals; Collagen; Combined Modality Therapy; Disease Models, Animal; Hydroxyproline; Laparotomy; Ma | 2006 |
Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Gi | 2006 |
Colchicine in experimental alkaline burns of the rat esophagus: an old drug, a new indication?
Topics: Analysis of Variance; Animals; Burns, Chemical; Caustics; Colchicine; Disease Models, Animal; Dose-R | 2006 |
Citrus juice modulates bone strength in male senescent rat model of osteoporosis.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Antioxidants; Beverages; Bone and Bones; Bone Densi | 2006 |
Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle.
Topics: Animals; Collagen Type I; Collagen Type III; Diaphragm; Disease Models, Animal; Enzyme Inhibitors; F | 2006 |
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats.
Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hydroxyprolin | 2006 |
Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Combined Modality Therapy; Disease Models, Animal; Female | 2006 |
Effect of peritoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis.
Topics: Anastomosis, Surgical; Animals; Anti-Infective Agents, Local; Colon; Disease Models, Animal; Female; | 2006 |
[Immune complex induced rat liver fibrosis model by intraperitoneal injection of human serum albumin].
Topics: Animals; Antigen-Antibody Complex; Disease Models, Animal; Fibrosis; Humans; Hyaluronic Acid; Hydrox | 2006 |
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.
Topics: Aging; Animals; Body Weight; Cobra Cardiotoxin Proteins; Disease Models, Animal; Fibrosis; Gene Dele | 2006 |
Effects of a static magnetic field on wound healing: results in experimental rat colon anastomoses.
Topics: Anastomosis, Surgical; Animals; Biomarkers; Colon, Descending; Disease Models, Animal; Electromagnet | 2006 |
Novel pirfenidone analogues: synthesis of pyridin-2-ones for the treatment of pulmonary fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspart | 2006 |
Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline.
Topics: Animals; Calcium; Calcium Oxalate; Creatinine; Dinoprost; Disease Models, Animal; Gene Expression Re | 2006 |
Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.
Topics: Animals; Cells, Cultured; Collagen; Dermis; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; | 2006 |
[Kinetics and mechanism in bleomycin-induced murine pulmonary fibrosis model].
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Lung; Male | 2006 |
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.
Topics: Administration, Inhalation; Animals; Collagen; Cytokines; Disease Models, Animal; Hydroxyproline; In | 2006 |
Therapeutic effect of Chinese medicine formula DSQRL on experimental pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Collagen; Disease Models, Animal; Drugs | 2007 |
Effects of retinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice.
Topics: Animals; Collagen Type I; Disease Models, Animal; Gene Expression; Hydroxyproline; Liver Cirrhosis, | 2007 |
Coagulation factor Xa modulates airway remodeling in a murine model of asthma.
Topics: Amphiregulin; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Collagen; Disease Mode | 2007 |
Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Fatty Liver; | 2006 |
[Influence of propyl-thiouracil-induced hypothyroidism on rat gingival mucosa].
Topics: Animals; Antithyroid Agents; Collagen; Colorimetry; Disease Models, Animal; DNA; Gingiva; Hydroxypro | 2006 |
Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats.
Topics: Administration, Oral; Animals; Bleomycin; Body Weight; Disease Models, Animal; Dose-Response Relatio | 2007 |
Transient profound mesenteric ischemia strongly affects the strength of intestinal anastomoses in the rat.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Follow-Up Studies; Gelatinases; Hydro | 2007 |
Protective effect of verapamil on multiple hepatotoxic factors-induced liver fibrosis in rats.
Topics: Actins; Alanine Transaminase; Animals; Carbon Tetrachloride; Collagen; Dietary Fats; Disease Models, | 2007 |
Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Capillaria; Chronic Disease; Disease Models, Anim | 2006 |
Wound-healing activity of Morinda citrifolia fruit juice on diabetes-induced rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Exp | 2007 |
Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
Topics: Animals; Bile Ducts; Biomarkers; Cell Survival; Cells, Cultured; Disease Models, Animal; Epithelium; | 2007 |
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.
Topics: Animals; Antigens, Viral; Arginase; beta-N-Acetylhexosaminidases; Biomarkers; Bronchoalveolar Lavage | 2007 |
A comparative study on several models of experimental renal calcium oxalate stones formation in rats.
Topics: Ammonium Chloride; Animals; Blood Urea Nitrogen; Calcium; Calcium Gluconate; Calcium Oxalate; Creati | 2007 |
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; | 2007 |
Evaluation of Tectona grandis leaves for wound healing activity.
Topics: Administration, Oral; Administration, Topical; Aloe; Animals; Burns; Chemistry, Pharmaceutical; Derm | 2007 |
[Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Becaplermin; Benzamides; Bleomycin; Disease Models, Animal; Hydroxyproline; Imatinib Mesyla | 2007 |
Anti-fibrotic effect of meloxicam in a murine lung fibrosis model.
Topics: Animals; Antioxidants; Bleomycin; Collagen; Cyclooxygenase Inhibitors; Disease Models, Animal; Gluta | 2007 |
Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Collagen; Disease Mod | 2007 |
Inhibitory effects of soy isoflavones on cardiovascular collagen accumulation in rats.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Cardiovascular System | 2007 |
Effects of a membrane-permeable radical scavenger, Tempol, on healing of colonic anastomoses in the cecal ligation and puncture model of polymicrobial sepsis in rats.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Biomarkers; Colon; Cyclic N-Oxides; Disease Models, An | 2007 |
An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination; Herbicides; HSP | 2007 |
Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty | 2007 |
Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Colon; Colonic Diseases; Disease Models, Animal; Gluta | 2007 |
A new murine model for bronchiolitis obliterans post-bone marrow transplant.
Topics: Animals; Bone Marrow Transplantation; Bronchiolitis Obliterans; Chemokines; Cytokines; Disease Model | 2007 |
Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents; Clostridium histolyticum; Disease Models, Animal; Hydroxyproline; | 2007 |
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Cholangitis, Sclerosing; Cholesterol; Dicarbethoxydihydro | 2007 |
A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Ileum; Ischemia; Male | 2007 |
Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Bronchopulmonary Dysplasia; Cathepsins; Col | 2007 |
Wound healing activity of Matricaria recutita L. extract.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Matricaria; Phytotherapy; Plant Preparations; Rats; | 2007 |
Treatment of chronic liver injuries in mice by oral administration of ethanolic extract of the fruit of Hovenia dulcis.
Topics: Administration, Oral; Animals; Aspartate Aminotransferase, Cytoplasmic; Carbon Tetrachloride; Chemic | 2007 |
Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury.
Topics: Animals; Ascorbic Acid; Benzoates; Central Nervous System Depressants; Collagen; Disease Models, Ani | 2007 |
Dietary oxalate and calcium oxalate nephrolithiasis.
Topics: Animals; Calcium Oxalate; Creatinine; Dietary Supplements; Disease Models, Animal; Follow-Up Studies | 2007 |
Role of allopurinol on oxidative stress in caustic burn: cure for stricture?
Topics: Allopurinol; Animals; Biomarkers; Burns, Chemical; Caustics; Disease Models, Animal; Esophageal Sten | 2007 |
Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxid | 2008 |
Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Biomarkers; Body Weight; Calcium; Cathepsin K; Cath | 2007 |
Topical diphenylhydantoin sodium can improve healing in a diabetic incisional animal wound model.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Evaluation, Preclin | 2007 |
An evaluation of normal saline and taurolidine on intra-abdominal adhesion formation and peritoneal fibrinolysis.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Female; Fibrinolysis; Hydroxyproline; Perito | 2008 |
[Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model].
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Paraquat; Placenta Growth Factor; Pre | 2007 |
[Effects of reduced glutathione on contents of hydroxyproline and oxidation stress reaction in kidney of unilateral ureteral obstruction in rat].
Topics: Animals; Disease Models, Animal; Female; Glutathione; Hydroxyproline; Kidney; Male; Malondialdehyde; | 2007 |
Effectiveness of etanercept in bleomycin-induced experimental scleroderma.
Topics: Animals; Antirheumatic Agents; Bleomycin; Cytokines; Disease Models, Animal; Etanercept; Female; Hyd | 2008 |
Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Body Weight; Cluster Analysis; Collagen; Disease M | 2007 |
Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Division; Chemokine CXCL2; Chemokines; Collagen; Disease | 2008 |
Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Body Weight; Collagen; Desmosine; Diabetes Me | 2008 |
Biochemical and histopathologic effects of omeprazole and vitamin E in rats with corrosive esophageal burns.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Burns, Chemical; Disease Models, Animal; Drug Therapy, Com | 2008 |
Wound healing activity of Persea americana (avocado) fruit: a preclinical study on rats.
Topics: Administration, Cutaneous; Administration, Oral; Analysis of Variance; Animals; Disease Models, Anim | 2008 |
Comparison between conventional and "clinical" assessment of experimental lung fibrosis.
Topics: Adenoviridae; Animals; Collagen; Disease Models, Animal; Disease Progression; Female; Gene Transfer | 2008 |
Reproducible long-term disc degeneration in a large animal model.
Topics: Animals; Chondroitin ABC Lyase; Chronic Disease; Disease Models, Animal; Female; Glycosaminoglycans; | 2008 |
Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition.
Topics: Animals; Arginine; Calcium Oxalate; Crystallization; Disease Models, Animal; Dose-Response Relations | 2008 |
Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bleomycin | 2008 |
Enzymuria (the output of gamma-glutamyl-transpeptidase and of N-acetyl-beta-D-glucosaminidase) in the course of experimental renovascular hypertension.
Topics: Acetylglucosaminidase; Animals; Blood Pressure; Disease Models, Animal; Female; gamma-Glutamyltransf | 1981 |
Carbon tetrachloride-induced hepatic fibrosis and cirrhosis in the developing rat: an experimental model of cirrhosis in childhood.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 1983 |
Auricular chondritis in fawn-hooded rats. A spontaneous disorder resembling that induced by immunization with type II collagen.
Topics: Animals; Cartilage Diseases; Collagen; Diagnosis, Differential; Disease Models, Animal; DNA; Ear Car | 1984 |
Functional and biochemical indicators of pneumoconiosis in mice: comparison with rats.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Lung Volume Measurements; Mice; Organ | 1984 |
Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Hydroxyproline; Mice; Mice, Mutant Strains; Organ Cu | 1984 |
[An experimental model of osteoarthritis. II.- Biochemical study of collagen and proteoglycans].
Topics: Animals; Cartilage, Articular; Chemical Phenomena; Chemistry; Collagen; Disease Models, Animal; Hydr | 1984 |
Correlation between Ito cells and fibrogenesis in an experimental model of hepatic fibrosis. A sequential stereological study.
Topics: Animals; Cell Count; Disease Models, Animal; Fibroblasts; Hydroxyproline; Liver; Liver Cirrhosis; Ma | 1983 |
The effect of chronic alcoholism on wound healing.
Topics: Alcoholism; Animals; Disease Models, Animal; Granuloma; Humans; Hydroxyproline; Male; Mice; Skin; Te | 1981 |
Plasma free hydroxyproline, growth, and sexual maturity in the scoliotic chicken.
Topics: Animals; Chickens; Collagen; Disease Models, Animal; Female; Growth; Hydroxyproline; Male; Poultry D | 1980 |
Pathophysiology of congenital diaphragmatic hernia. XI: Anatomic and biochemical characterization of the heart in the fetal lamb CDH model.
Topics: Animals; Aorta; Blood Pressure; Collagen; Disease Models, Animal; DNA; Ductus Arteriosus, Patent; El | 1995 |
Pathophysiology of congenital diaphragmatic hernia. XVI: Elevated pulmonary collagen in the lamb model of congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Bronchi; Collagen; Disease Models, Animal; DNA; Elastin; Female; Gestational Ag | 1995 |
Suppressive effect of anti-alpha 1-antichymotrypsin serum on pulmonary fibrosis induced by phorbol myristate acetate in vivo.
Topics: alpha 1-Antichymotrypsin; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Cells, Cultured; Co | 1995 |
Dose and regimen effects of poly ICLC, an interferon inducer, in a multi-dose bleomycin model of interstitial pulmonary fibrosis.
Topics: Animals; Bleomycin; Carboxymethylcellulose Sodium; Cricetinae; Disease Models, Animal; Dose-Response | 1994 |
Heterogeneous decrease of bone mineral density in the vertebral column of ovariectomized rats.
Topics: Absorptiometry, Photon; Alkaline Phosphatase; Analysis of Variance; Animals; Body Weight; Bone Densi | 1995 |
Effects of angiotensin-converting enzyme inhibitor and aldosterone antagonist on myocardial collagen in cardiomyopathic hamsters.
Topics: Aging; Animals; Body Weight; Canrenoic Acid; Captopril; Cardiomyopathies; Collagen; Cricetinae; Dise | 1995 |
The anabolic effect of human PTH (1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate--is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?
Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Dens | 1995 |
Peripheral vascular alterations during experimental heart failure in the rat. Do they exist?
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Flow Velocity; Blood Vessels; Cardiac Output, Low; | 1995 |
Correlation between high resolution computed tomography and tissue morphometry of the lung in bleomycin-induced pulmonary fibrosis in the rabbit.
Topics: Analysis of Variance; Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Oxygen | 1993 |
Streptozotocin and alloxan are comparable agents in the diabetic model of impaired wound healing.
Topics: Alloxan; Analysis of Variance; Animals; Collagenases; Diabetes Mellitus, Experimental; Disease Model | 1993 |
Parathyroidectomy does not prevent bone loss in the oophorectomized rat.
Topics: Alkaline Phosphatase; Animals; Bone Density; Calcium; Disease Models, Animal; Female; Femur; Hydroxy | 1994 |
Hapten-immune pulmonary interstitial fibrosis (HIPIF) in mice requires both CD4+ and CD8+ T lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Disease Models, | 1993 |
Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.
Topics: Amino Acids; Animals; Choline Deficiency; Diet; Disease Models, Animal; Glutathione Transferase; Hyd | 1994 |
Consequences of prolonged inhalation of ozone on Fischer-344/N rats: collaborative studies. Part I: Content and cross-linking of lung collagen.
Topics: Air Pollutants; Animals; Chronic Disease; Collagen; Cross-Linking Reagents; Disease Models, Animal; | 1994 |
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Hydro | 1994 |
Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: application to the study of intravenous 14C-labeled 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate.
Topics: Animals; Bone Resorption; Creatinine; Diphosphonates; Disease Models, Animal; Dose-Response Relation | 1994 |
Surgically induced uremia in rats. I: Effect on bone strength and metabolism.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Cholecalciferol; Chronic Kidney | 1993 |
A novel in vivo model for the study of cartilage degradation.
Topics: Animals; Cartilage Diseases; Cartilage, Articular; Cattle; Disease Models, Animal; Hydroxyproline; I | 1993 |
A new model of progressive pulmonary fibrosis in rats.
Topics: Administration, Inhalation; Animals; Collagen; Desmosine; Disease Models, Animal; DNA; Elastin; Envi | 1993 |
Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis.
Topics: Animals; Collagen; Disease Models, Animal; Female; Fibrosis; Gelatin Sponge, Absorbable; Humans; Hyd | 1993 |
Immunological characterization of (tight skin/NZB)F1 hybrid mice with connective tissue and autoimmune features resembling human systemic sclerosis.
Topics: Animals; Autoantibodies; Collagen; Connective Tissue; Cytokines; Disease Models, Animal; Hydroxyprol | 1993 |
Dose dependency and wound healing aspects of the use of tissue plasminogen activator in the prevention of intra-abdominal adhesions.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Ischemia; Ligatio | 1993 |
Circulating levels and bone contents of bone gamma-carboxyglutamic acid-containing protein in rat models of non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Bone and Bones; Bone Diseases, Metabolic; Calcium; Diabetes Mellitus, Experi | 1993 |
The use of angiostatic steroids to inhibit cartilage destruction in an in vivo model of granuloma-mediated cartilage degradation.
Topics: Animals; Cartilage; Cortisone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therap | 1993 |
Amiodarone-induced pulmonary fibrosis in Fischer 344 rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Carbon Monoxide; Diffusion; Disease Models, Animal; Fem | 1996 |
[Collagen metabolism disturbances with experimentally increased pulmonary flow--experimental model of left to right shunt with congenital heart defects in children].
Topics: Anastomosis, Surgical; Animals; Biopsy; Collagen; Disease Models, Animal; Female; Heart Defects, Con | 1995 |
Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis.
Topics: Animals; Cholestasis; Disease Models, Animal; Female; Humans; Hydroxyproline; Liver Cirrhosis, Exper | 1996 |
Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats.
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Bone Density; Bone Resorption; Cell Division; D | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabe | 1996 |
Acute protein-calorie malnutrition impairs wound healing: a possible role of decreased wound nitric oxide synthesis.
Topics: Acute Disease; Amino Acids; Animals; Cells, Cultured; Collagen; Disease Models, Animal; DNA; Hydroxy | 1997 |
Ischemia and reperfusion of the porcine myocardium: effect on collagen.
Topics: Analysis of Variance; Animals; Biomarkers; Collagen; Collagen Type I; Creatine Kinase; Disease Model | 1997 |
Bilateral tibial marrow ablation in rats induces a rapid hypercalcemia arising from extratibial bone resorption inhibitable by methylprednisolone or deflazacort.
Topics: alpha-Macroglobulins; Animals; Bone Marrow; Bone Resorption; Calcium; Disease Models, Animal; Fractu | 1997 |
Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat.
Topics: Aging; Animals; Colchicine; Disease Models, Animal; Fibrosis; Heart; Hydroxyproline; Hypertension; M | 1997 |
Effects of 72 hours sleep deprivation on wound healing in the rat.
Topics: Animals; Biopsy; Disease Models, Animal; DNA; Fibroblasts; Granulocytes; Hydroxyproline; Macrophages | 1997 |
Extensive damage to the end-plates as a complication of laser discectomy. An experimental study using an animal model.
Topics: Animals; Cartilage, Articular; Cervical Vertebrae; Disease Models, Animal; Diskectomy; Guinea Pigs; | 1997 |
Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Disease Models, Animal; Fibrosis; Hydroxyprolin | 1997 |
The use of Chinese herbal medicine on experimental fracture healing.
Topics: Administration, Oral; Administration, Topical; Animal Feed; Animals; Body Weight; Collagen; Disease | 1997 |
Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cytokines; | 1997 |
[Effects of diacerhein on cytokine determinations in a model of cartilage degradation induced by granuloma in mice].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; D | 1997 |
Staphylococcal septic arthritis: antibiotic and nonsteroidal anti-inflammatory drug treatment in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Cartilage, Articular; Ceftr | 1997 |
Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cell Adhesion; Cricetinae; Dextrans; Di | 1998 |
Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Granuloma; Hydroxyproline; Lu | 1998 |
Pirfenidone improves renal function and fibrosis in the post-obstructed kidney.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Collagen; Disea | 1998 |
Glycoprotein composition in cyclophosphamide-induced lung fibrosis.
Topics: Animals; Cyclophosphamide; Disease Models, Animal; Endopeptidases; Fibrosis; Glycoproteins; Glycosyl | 1998 |
Production of superoxide and nitric oxide by alveolar macrophages in the bleomycin-induced interstitial pneumonia mice model.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Disease Models, Animal; Hydroxyproline; Immunohistochemis | 1998 |
The preventive effect of heparin on stricture formation after caustic esophageal burns.
Topics: Animals; Burns, Chemical; Caustics; Disease Models, Animal; Esophageal Stenosis; Esophagus; Heparin; | 1999 |
Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908).
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Desmosine; Disease Models, Animal; | 1999 |
[Effect of KW-8232 on bone turnover in ovariectomized rats].
Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Bone Resorption; Calcium; Disease Models, | 1998 |
The influence of hypothyroidism on wound healing. An experimental study.
Topics: Animals; Biomarkers; Collagen; Disease Models, Animal; Hydroxyproline; Hypothyroidism; Male; Rats; R | 1999 |
Advanced glycation in D-galactose induced mouse aging model.
Topics: Aging; Animals; Avoidance Learning; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Erythr | 1999 |
Dimethylnitrosamine-induced hepatic cirrhosis: a new canine model of an ancient human disease.
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Female; Humans; Hydroxyproline; Liver; L | 1970 |
Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Injections, Intravenous; Mannitol; Mice; | 1999 |
Animal model of sclerotic skin. II. Bleomycin induced scleroderma in genetically mast cell deficient WBB6F1-W/W(V) mice.
Topics: Animals; Antibiotics, Antineoplastic; Biopsy; Bleomycin; Cell Count; Disease Models, Animal; Female; | 1999 |
Alteration in aortic wall stiffness and accumulation of collagen during the prediabetic stage of type II diabetes mellitus in rats.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Experimental; Diabetes Mell | 1999 |
Hepatic fibrogenesis using chronic arsenic ingestion: studies in a murine model.
Topics: Animals; Arsenic; Collagen; Disease Models, Animal; Hydroxyproline; Liver Cirrhosis, Experimental; M | 1999 |
A time course study for the development of an immunocompromised wound model, using hydrocortisone.
Topics: Adrenal Glands; Animals; Cell Division; Disease Models, Animal; DNA; Hydrocortisone; Hydroxyproline; | 1999 |
The effect of octreotide on postoperative adhesion formation.
Topics: Animals; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrinolysis; Growth Substa | 2000 |
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Ascites; Aspartate Aminot | 2000 |
Heart failure development in rats with ascending aortic constriction and angiotensin-converting enzyme inhibition.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiac Output, Low; | 2000 |
The ethanol-soluble part of a hot-water extract from Artemisia iwayomogi inhibits liver fibrosis induced by carbon tetrachloride in rats.
Topics: Animals; Artemisia; Carbon Tetrachloride; Disease Models, Animal; Ethanol; Hot Temperature; Hydroxyp | 2000 |
The Fas/Fas-ligand system is not required for bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Hydroxyproline; In Sit | 2000 |
Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation | 2000 |
Effect of diacetyl rhein on the development of experimental osteoarthritis. A biochemical investigation.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cartilage, Articular; | 1996 |
Hepatocyte growth factor attenuates collagen accumulation in a murine model of pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Bleomycin; Cells, Cultured; Collagen; Disease | 2000 |
Effect of pyloric drainage on the healing of esophagogastric anastomoses in rats.
Topics: Anastomosis, Surgical; Animals; Disease Models, Animal; Drainage; Esophagectomy; Esophagus; Female; | 2000 |
Immunoglobulin responses to experimental silicosis.
Topics: Administration, Inhalation; Animals; B-Lymphocyte Subsets; Bronchoalveolar Lavage Fluid; Cells, Cult | 2001 |
Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2001 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collage | 2001 |
CD40/CD40 ligand interactions are critical for elicitation of autoimmune-mediated fibrosis in the lung.
Topics: Animals; Antibodies, Blocking; Autoimmune Diseases; Bronchoalveolar Lavage Fluid; CD40 Antigens; CD4 | 2001 |
Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemotaxis; Disease Models, Animal; Female; Hydroxyproline; I | 2001 |
Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Disease Models, Animal; Hydr | 2001 |
Rat model of lung fibrosis: comparison of functional, biochemical, and histopathological changes 4 months after single irradiation of the right hemithorax.
Topics: Airway Resistance; Animals; Disease Models, Animal; Histocytochemistry; Hydroxyproline; Lung; Lung V | 2001 |
Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Crystallization; Disease Models, Animal; Flow Cytometry; Gene | 2001 |
Pulmonary fibrosis is increased in mice carrying the factor V Leiden mutation following bleomycin injury.
Topics: Activated Protein C Resistance; Animals; Bleomycin; Disease Models, Animal; Factor V; Hydroxyproline | 2001 |
Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model.
Topics: Animals; Capillaria; Case-Control Studies; Disease Models, Animal; Female; Hydroxyproline; Immunolog | 2001 |
Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Circadian Rhythm; Collagen; Coll | 2001 |
Attenuation of bleomycin-induced pneumopathy in mice by monoclonal antibody to interleukin-12.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cyt | 2001 |
Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Arthritis, | 2001 |
Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse.
Topics: Animals; Bleomycin; Blood Coagulation; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Anima | 2001 |
Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Disease Models, Animal; Dose-Response Relationship, | 2001 |
Oxaceprol, an atypical inhibitor of inflammation, reduces leukocyte adherence in mouse antigen-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Cell Adhesion; Disease Models | 2001 |
Temporary warm ischaemia, 5/6 nephrectomy and single uranyl nitrate administration--comparison of three models intended to cause renal fibrosis in rats.
Topics: Animals; Creatinine; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Kidney; Nephrectomy; | 2001 |
Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction.
Topics: Animals; Collagen; Dilatation, Pathologic; Disease Models, Animal; Echocardiography; Enzyme Inhibito | 2001 |
Protection from pulmonary fibrosis in leukotriene-deficient mice.
Topics: Animals; Anti-Bacterial Agents; Arachidonate 5-Lipoxygenase; Bleomycin; Bronchoalveolar Lavage Fluid | 2002 |
[Dynamic changes in dermal cell cycles, contents of hydroproline and ratios of collagen type I/III in the burned wound].
Topics: Animals; Burns; Cell Cycle; Collagen; Disease Models, Animal; Female; Hydroxyproline; Male; Rats; Ra | 2000 |
Captopril inhibits the pulmonary toxicity of paraquat in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Combinati | 2001 |
Polyunsaturated phosphatidylcholine lowers collagen deposition in a rat model of corrosive esophageal burn.
Topics: Animals; Burns, Chemical; Collagen; Disease Models, Animal; Esophageal Stenosis; Esophagus; Female; | 2002 |
Dynamic pattern of IGF-I and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Collagen Type I; Disease Models, | 2002 |
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers; | 2002 |
Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Bleomycin; Disease Models, | 2002 |
Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni.
Topics: Animals; Collagen; Disease Models, Animal; Granuloma; Hydroxyproline; Immunohistochemistry; Leptin; | 2002 |
CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, CD19; Antigens, Differe | 2002 |
A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis.
Topics: Activating Transcription Factor 2; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar | 2002 |
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; L | 1979 |
Evaluation of urinary alkaline ribonuclease activity in the assessment of subclinical malnutrition in weanling rats.
Topics: Animals; Clinical Enzyme Tests; Creatinine; Disease Models, Animal; Food; Hydrogen-Ion Concentration | 1979 |
Alaskan malamute chondrodysplasia. II. Urinary excretion of hydroxyproline, uronic acid and acid mucopolysaccharides.
Topics: Animals; Disease Models, Animal; Dog Diseases; Dogs; Glycosaminoglycans; Hydroxyproline; Osteochondr | 1976 |
The structural proteins of normal and diseased human myocardium.
Topics: Actomyosin; Adult; Aged; Animals; Cardiomegaly; Collagen; Coronary Disease; Disease Models, Animal; | 1978 |
Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resportion.
Topics: Animals; Antigens; Bone Resorption; Calcium; Calcium, Dietary; Cattle; Cattle Diseases; Cyclic AMP; | 1976 |
Comparative study on the composition of the organic matrix of the long bones of the "normal" rat and of the mutant Op/Orl.
Topics: Amino Acids; Animals; Bone Matrix; Chondroitin Sulfates; Disease Models, Animal; Edetic Acid; Femur; | 1977 |
An experimental model of hepatic fibrosis induced by the administration of dibutyltin dichloride.
Topics: Animals; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Liver; | 1979 |
Pharmacological studies on experimental nephritic rats (3). Changes in the connective tissue components of renal cortex in the modified type of Masugi's nephritis.
Topics: Animals; Blood Proteins; Cholesterol; Disease Models, Animal; Hexosamines; Hydroxyproline; Kidney Co | 1978 |
The effect of uremia on wound tensile strength and collagen formation.
Topics: Animals; Body Weight; Collagen; Creatinine; Disease Models, Animal; Energy Intake; Hydroxyproline; R | 1977 |
Beta-aminopropionitrile as a radiation reaction preventive agent.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Letha | 1976 |
[Study of urinary excretion of hydroxyproline in experimental silicosis].
Topics: Animals; Disease Models, Animal; Hydroxyproline; Male; Rats; Silicosis | 1976 |
Metabolic recovery of articular cartilage after intra-articular injections of glucocorticoid.
Topics: Animals; Cartilage Diseases; Cartilage, Articular; Collagen; Disease Models, Animal; DNA; Hexosamine | 1976 |
The action of the benzopyrones on an experimental model of lymphoedema: a contribution to their mode of action.
Topics: Amino Acids; Animals; Benzopyrans; Blood Proteins; Disease Models, Animal; Female; Hydroxyproline; L | 1976 |
[Chronic thioacetamide poisoning as a model for experimental liver cirrhosis].
Topics: Acetamides; Amino Acids; Animals; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Liver Cir | 1976 |
Biochemical confirmation of an experimental osteoarthritis model.
Topics: Acid Phosphatase; Animals; Cartilage, Articular; Disease Models, Animal; Femur; Glycine; Glycosamino | 1975 |
The carbon-tetrachloride-hepatotoxicity as a model of liver damage. First report: Long-time biochemical changes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Butyryl | 1975 |
cis-hydroxyproline limits work necessary to flex a digit after tendon injury.
Topics: Animals; Biomechanical Phenomena; Cicatrix; Collagen; Disease Models, Animal; Dose-Response Relation | 1975 |
Altered arterial connective tissue in racing greyhound dogs.
Topics: Animals; Arteries; Collagen; Disease Models, Animal; Dogs; Elastin; Hydroxyproline; Running | 1975 |
Development of a bleomycin hamster model of subchronic lung fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cricetinae; Disease Models | 1992 |
[Comparative analysis of biological aggressiveness of dusts from different coal mines for determining the risk of development of pneumoconiosis among miners].
Topics: Air Pollutants, Occupational; Animals; Anthracosilicosis; Coal Mining; Disease Models, Animal; Dust; | 1992 |
[Effect of tranilast, an anti-allergic drug, on the human keloid tissues].
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Matrix; Fib | 1992 |
[Effect of Z-103 on wound healing by dermal incision in guinea pigs].
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; Guinea Pigs; Hydroxyproli | 1992 |
Preliminary observations of chondral abrasion in a canine model.
Topics: Animals; Anterior Cruciate Ligament; Cartilage, Articular; Disease Models, Animal; Dogs; Femur; Hind | 1992 |
Dependence of ultrasonic attenuation of liver on pathologic fat and fibrosis: examination with experimental fatty liver and liver fibrosis models.
Topics: Adipose Tissue; Animals; Body Water; Collagen; Disease Models, Animal; Fatty Liver; Hydroxyproline; | 1992 |
An experimental model of osteoarthrosis in the temporomandibular joint of the rabbit.
Topics: Animals; Bone Remodeling; Cartilage, Articular; Collagen; Disease Models, Animal; Fibroblasts; Glyco | 1992 |
Pressure overload-induced cardiac hypertrophy with and without dilation.
Topics: Animals; Aorta; Biopsy; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Disease Models, Animal; | 1992 |
Tamoxifen in the rat prevents estrogen-deficiency bone loss elicited with the LHRH agonist buserelin.
Topics: Animals; Body Weight; Bone Diseases, Metabolic; Bone Resorption; Buserelin; Calcium; Disease Models, | 1992 |
Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cadmium; Cadmium Chloride; Cell Count; Chlorides; Disease Mod | 1992 |
[Studies on the healing promoting action of Z-103 in chronic gastric ulcer models of rats].
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; DNA; Hydroxyproline; Male | 1992 |
Regulation of bone turnover and prevention of bone atrophy in ovariectomized beagle dogs by the administration of 24R,25(OH)2D3.
Topics: 24,25-Dihydroxyvitamin D 3; Animals; Bone and Bones; Bone Resorption; Disease Models, Animal; Dogs; | 1992 |
[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].
Topics: Air Pollutants; Animals; Chemical Industry; Coke; Disease Models, Animal; Dust; Ferric Compounds; Hy | 1991 |
[Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue].
Topics: Air Pollutants, Occupational; Animals; Anthracosilicosis; Coal Mining; Disease Models, Animal; Dust; | 1991 |
[Effect of selenium on the connective tissue metabolism in rats].
Topics: Animals; Chronic Disease; Connective Tissue; Disease Models, Animal; Glycosaminoglycans; Hydroxyprol | 1991 |
The blotchy mouse, lung desmosine, and emphysema.
Topics: Animals; Desmosine; Disease Models, Animal; Hydroxyproline; Lung; Mice; Protein-Lysine 6-Oxidase; Pu | 1991 |
The influence of a histamine2-receptor antagonist on the healing of an experimentally induced gastric mucosal lesion.
Topics: Animals; Cell Division; Disease Models, Animal; DNA; Gastric Mucosa; Histamine H2 Antagonists; Hydro | 1990 |
Chronic administration of ethanol with high vitamin A supplementation in a liquid diet to rats does not cause liver fibrosis. 1. Morphological observations.
Topics: Animals; Biopsy; Diet; Disease Models, Animal; Ethanol; Hydroxyproline; Liver Cirrhosis, Alcoholic; | 1991 |
[Effect of chronic mercuric chloride poisoning on the levels of connective tissue metabolites in the urine and blood of rats].
Topics: Animals; Chronic Disease; Connective Tissue; Disease Models, Animal; Glycosaminoglycans; Hydroxyprol | 1991 |
[Evaluation of the effect of the detergent Rokafenol N-8 on the development and course of experimental pneumoconiosis caused by coal mine dust].
Topics: Administration, Inhalation; Animals; Anthracosilicosis; Coal; Coal Mining; Detergents; Disease Model | 1991 |
[Basal studies on the model of circular excisional wounds made on the dorsal skin of rats treated with hydrocortisone].
Topics: Animals; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrocortis | 1991 |
Excretion of urinary hydroxyproline in correlation with severity of induced osteomyelitis in rabbits.
Topics: Animals; Body Weight; Collagen; Disease Models, Animal; Hemodynamics; Hydroxyproline; Osteomyelitis; | 1991 |
Short term functional effects of bladder outlet obstruction in the cat.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Cats; Disease Models, Animal; F | 1990 |
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Asbestosis; Bronchoalveolar Lavage Fluid; Catalase; Diseas | 1990 |
EGF increases short-term type I collagen accumulation during wound healing in diabetic rats.
Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Diabetes Mellitus, Experimental; D | 1990 |
The effects of testosterone propionate and methenolone enanthate on the healing of humeral osteotomies in the Wistar rat.
Topics: Animals; Bony Callus; Calcium; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclin | 1990 |
The effect of perfluorochemical fluosol-DA (20%) on myocardial infarct healing in the rabbit.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Combinations; Fluorocarbons; Foam Cells; | 1990 |
Trabecular bone remodeling and bone mineral density in the adult cat during chronic dietary acidification with ammonium chloride.
Topics: Acidosis; Ammonium Chloride; Animal Feed; Animals; Biopsy; Bone Density; Bone Development; Bone Reso | 1990 |
Morphometric studies on wound healing after systemic administration of adriamycin and local application of fibrin sealant. Application of a new wound healing model using spongiosa implants.
Topics: Animals; Aprotinin; Disease Models, Animal; DNA; Doxorubicin; Drug Combinations; Factor XIII; Fibrin | 1986 |
Protein metabolism and fibrosis in experimental canine obstructive lymphedema.
Topics: alpha-Macroglobulins; Animals; Collagen; Disease Models, Animal; Dogs; Extracellular Space; Fibrosis | 1987 |
High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Female; Hydroxyproline; Lung; Mice; Mice, Inbred BALB C; | 1987 |
Ameliorating effect of an interferon inducer polyinosinic-polycytidylic acid on bleomycin-induced lung fibrosis in hamsters. Morphologic and biochemical evidence.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Disease Models, Animal; Hydr | 1988 |
Collagen breakdown during acute lung injury.
Topics: Acute Disease; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; E | 1988 |
Wound healing in nude mice: a study on the regulatory role of lymphocytes in fibroplasia.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Evaluation Studies as Topic; Hydroxyproline | 1989 |
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Histo | 1989 |
Therapeutic treatment of canine osteoarthritis with glycosaminoglycan polysulfuric acid ester.
Topics: Animals; Cartilage, Articular; Disease Models, Animal; Dogs; Glycosaminoglycans; Hydroxyproline; Met | 1989 |
The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Body Weight; Collagen; Deficiency Diseases; Disease Models, | 1989 |
Thioacetamide-induced cirrhosis-like liver lesions in rats--usefulness and reliability of this animal model.
Topics: Acetamides; Acetylglucosaminidase; Animals; Disease Models, Animal; Female; Hydroxyproline; Liver; L | 1988 |
The role of neutrophils in the development of cadmium chloride-induced emphysema in lathyrogen-fed hamsters.
Topics: Aminopropionitrile; Amitrole; Animals; Cadmium; Cadmium Chloride; Cricetinae; Disease Models, Animal | 1985 |
Humoral hypercalcemia of malignancy in nude mouse model of a canine adenocarcinoma derived from apocrine glands of the anal sac. Biochemical, histomorphometric, and ultrastructural studies.
Topics: Adenocarcinoma; Anal Gland Neoplasms; Anal Sacs; Animals; Apocrine Glands; Calcitriol; Calcium; Cycl | 1986 |
A biochemical method for the quantitation of myocardial scarring after experimental coronary artery occlusion.
Topics: Animals; Arteries; Chloramines; Collagen; Coronary Vessels; Disease Models, Animal; Heart Ventricles | 1986 |
The efficacy of subcutaneous goretex implants in monitoring wound healing response in experimental protein deficiency.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Methods; Nutritional Status; Prostheses and Implant | 1988 |
Late functional, biochemical and histological changes in the rat lung after fractionated irradiation to the whole thorax.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Hydroxyproline; Lung | 1987 |
Pulmonary interstitial fibrosis induced in hapten-immune hamsters.
Topics: Animals; Collagen; Cricetinae; Dermatitis, Contact; Disease Models, Animal; Haptens; Histocytochemis | 1987 |
Collagenous abnormalities in the heart of the tight-skin mouse.
Topics: Animals; Collagen; Creatine Kinase; Disease Models, Animal; Hexosamines; Hydroxyproline; Mice; Mice, | 1987 |
In vivo collagen metabolism in spontaneously diabetic (db/db) mice.
Topics: Animals; Collagen; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydroxyproline; Mice; Mice, Mu | 1986 |
[Participation of autoimmune and autoaggressive reactions in the mechanism of connective tissue disorganization].
Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; C | 1970 |
Nephrotoxic serum nephritis. I. Chemical, morphologic, and functional changes in the glomerular basement membrane during the evolution of nephritis.
Topics: Animals; Antigen-Antibody Reactions; Basement Membrane; Capillaries; Centrifugation; Disease Models, | 1970 |
The role of infection on wound healing.
Topics: Abdomen; Abscess; Animals; Collagen; Disease Models, Animal; Female; Hydroxyproline; Peritoneum; Pro | 1974 |
Mechanical properties of rat cardiac muscle during experimental hypertrophy.
Topics: Animals; Aorta, Thoracic; Cardiomegaly; Constriction; Disease Models, Animal; Elasticity; Heart; Hyd | 1971 |
Synthesis of collagen, myosin, noncollagenous protein, and DNA during experimental myocardial hypertrophy in the rat.
Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; DNA Replication; Hydroxyproline; Muscle Pro | 1972 |
Histamine metabolism in experimental silicosis. II. In vivo experiments in guinea pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Collagen; Disease Models, Animal; Guinea | 1971 |
Experimental silicosis of the rat. Correlation of functional, biochemical, and histological changes.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Hematocrit; Hemoglobinometry; Hydroxyproline; L | 1971 |
Debridement of experimental skin burns of pigs with bromelain, a pineapple-stem enzyme.
Topics: Animals; Anti-Bacterial Agents; Bromelains; Burns; Debridement; Disease Models, Animal; Dogs; Drug S | 1973 |
Effect of experimental chronic renal insufficiency on bone mineral and collagen maturation.
Topics: Animals; Bone and Bones; Bone Development; Bone Matrix; Calcium; Calcium Isotopes; Carbonates; Centr | 1972 |
Heparin osteoporosis. An experimental model using rats.
Topics: Animals; Biomechanical Phenomena; Bone and Bones; Collagen; Disease Models, Animal; Female; Fibrobla | 1973 |
[Heparin-induced osteopathy in animal experiments--a model for osteoporosis? Influence of heparin on the concentrations of hydroxyapatite, citrate, and hydroxyproline in the bones of rats of various ages. I].
Topics: Animals; Bone and Bones; Citrates; Disease Models, Animal; Heparin; Hydroxyapatites; Hydroxyproline; | 1973 |
[Experimental oxalic lithiases in rats. Influence of certain Krebs cycle intermediates].
Topics: Administration, Oral; Animals; Citrates; Citric Acid Cycle; Disease Models, Animal; Ethylene Glycols | 1973 |
The effects of azathioprine on CCl4 induced cirrhosis in the rat.
Topics: Adenosine Triphosphate; Animals; Azathioprine; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; | 1974 |
Metabolic and circulatory contributions to oxygen gradients in wounds.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Collagen; Disease Models, Animal; Hydroxyproline; Male | 1972 |
Inhibition of scar formation by the proline analog cis-hydroxyproline.
Topics: Animals; Cicatrix; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Postoperative Complicatio | 1972 |
Healing of colonic anastomoses following resection for experimental "diverticulitis".
Topics: Animals; Collagen; Colon; Colostomy; Disease Models, Animal; Diverticulitis, Colonic; Dogs; Feces; F | 1971 |
Biochemical changes in non-infarcted heart muscle following myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biopsy; Carbon Isotopes; Coronary Vessels; D | 1971 |
Protocollagen proline hydroxylase activity in experimental pulmonary fibrosis of rats.
Topics: Animals; Ascorbic Acid; Collagen; Disease Models, Animal; Hydroxyproline; Iron; Ketoglutaric Acids; | 1970 |