hydroxyproline has been researched along with Disease Models, Animal in 609 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (11.00) | 18.7374 |
| 1990's | 85 (13.96) | 18.2507 |
| 2000's | 198 (32.51) | 29.6817 |
| 2010's | 238 (39.08) | 24.3611 |
| 2020's | 21 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, Z; Gong, G; Guan, R; He, Y; Lai, Y; Li, Y; Luo, Y; Peng, X; Song, S; Su, J; Yang, P; Yin, H; Yu, J; Zhao, J; Zhao, S; Zhong, N | 1 |
| Feldstein, AE; Kaufmann, B; Kim, AD; Kim, DJ; Kim, SE; Leszczynska, A; Reca, A | 1 |
| Athari, SS; Li, M; Li, Y; Wang, B; Wang, J; Wang, R | 1 |
| Hu, J; Peng, L; Wang, L; Yang, H; Yang, M; Zhang, E | 1 |
| Hwang, DW; Ko, MK; Lee, M; Piao, C; Zhuang, C | 1 |
| Kotani, T; Matsuda, S; Saito, T; Sato, T; Suzuka, T; Takeuchi, T | 1 |
| Abdullah, A; Çiğdem, Y; Erhan, A; Tuğrul, EE | 1 |
| Cai, R; Delcroix, G; Griswold, AJ; Jackson, RM; Lazerson, A; Mirsaeidi, M; Schally, AV; Wangpaichitr, M; Zhang, C | 1 |
| Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S | 1 |
| Fan, CF; Song, D; Tang, YH; Xu, HH; Zhang, HX | 1 |
| Buchalski, B; Challa, A; Fargue, S; Holmes, RP; Knight, J; Lowther, WT; Wood, KD | 1 |
| Lei, L; Li, X; Lu, Y; Tao, Z; Wen, J; Zhao, C; Zheng, L | 1 |
| Chen, L; Chen, XZ; Wu, PB; Ye, HL; Zhang, G; Zhang, JW | 1 |
| Alaqeel, M; AlShaer, A; Anbazhagan, AN; Antoniou, J; Bergeron, SG; Epure, LM; Grant, MP; Huk, OL; Im, HJ; Kc, R; Mwale, F; Salem, O; Zukor, DJ | 1 |
| Ju, P; Li, YM; Qu, SJ; Shen, WP; Song, ZZ; Zhao, L | 1 |
| Gao, J; Mao, J; Tang, J; Wang, X; Zhang, H; Zhang, J | 1 |
| Adami, E; Chen, X; Cook, SA; Corden, B; Ko, NSJ; Lim, WW; Schafer, S; Song, W; Su, L; Tee, NGZ | 1 |
| Chen, XY; Feng, FC; He, HL; Li, RF; Xu, Y; Zhou, XM | 1 |
| Fujitaka, K; Hamada, H; Hattori, N; Horimasu, Y; Iwamoto, H; Masuda, T; Miyamoto, S; Nakanishi, Y; Nakashima, T; Ohshimo, S; Sakamoto, S; Yamaguchi, K | 1 |
| Böhm, M; Del Rey, A; Raker, V; Stegemann, A; Steinbrink, K | 1 |
| Atar, S; Bandel, N; Daud, E; Ertracht, O; Moady, G; Reuveni, T; Shehadeh, M | 1 |
| Harishankar, N; Husain, GM; Kazmi, MH; Potnuri, AG; Reddy, KP; Suresh, P | 1 |
| Li, J; Ren, G; Zhang, W | 1 |
| Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM | 1 |
| Arauz, J; Favari, L; Galicia-Moreno, M; Hernández-Aquino, E; Muriel, P; Segovia, J; Zarco, N | 1 |
| Jin, J; Li, J; Li, X; Wang, Q; Xiang, S; Zhang, L; Zhang, Q; Zhao, Z; Zhou, J | 1 |
| Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R | 1 |
| Bian, H; Duan, J; Li, W; Lin, R; Ma, T; Mu, F; Wei, G; Wen, A; Wu, X; Xi, M; Yang, Q | 1 |
| Chen, XJ; Gao, GZ; Jiang, WS; Liu, S; Yan, DX | 1 |
| Ebisu, G; Endo, N; Hino, K; Miyatake, S; Yamada, F | 1 |
| Choi, CS; Choi, DJ; Jeong, SH; Kim, JH; Kim, YS; Kwon, OS; Lee, JJ; Park, YH; Shin, SK | 1 |
| Liu, J; Wang, FS; Wang, X; Xu, K; Yang, XY; Zeng, Q | 1 |
| Chicco, A; Creus, A; Ferreira, MR; Lombardo, YB; Oliva, ME | 1 |
| Cui, R; Zhang, S | 1 |
| Francis, NK; Hota, T; Mitra, A; Pawar, HS; Peter, N | 1 |
| Hemmati, AA; Housmand, G; Jalali, A; Larki-Harchegani, A; Rezaei, A; Shabib, S | 1 |
| Anstee, QM; Dhar, A; Goldin, RD; Levene, AP; Sadiq, F; Thursz, MR | 1 |
| Feng, S; Gao, J; Li, Y | 1 |
| Godugu, C; Karkale, S; Khurana, A; Saifi, MA; Talla, V | 1 |
| Moore, BB; O'Dwyer, DN | 1 |
| He, Y; Jiang, Z; Liu, H; Mei, J; Shen, S; Tang, M | 1 |
| Dai, Z; Ji, Y; Ma, X; Sun, S; Tso, P; Wu, G; Wu, Z; Yang, Y | 1 |
| Dai, J; Dai, X; Fang, J; Feng, C; Hao, J; Hao, Y; Li, J; Li, R; Liu, J; Lu, B; Ma, R; Qiao, Z; Ran, Y; Xiong, W; Zhang, J; Zhou, Q | 1 |
| Ahad, A; Ahmad Ansari, M; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Ali, N; Khan, A; Raish, M | 1 |
| Fagagnini, S; Hausmann, M; Hünerwadel, A; Jaeger, SU; Lutz, C; Mamie, C; Rogler, G; Ruiz, PA; Weder, B | 1 |
| Mao, M; Sun, L; Yan, Z; Zhang, X; Zuo, C | 1 |
| Cui, D; Huang, S; Zhao, D | 1 |
| He, RH; Li, PF; Li, R; Rao, GT; Shi, SB; Wang, QT; Yang, B | 1 |
| Kalantar, H; Khodayar, MJ; Mansouri, E; Pashmforoosh, M; Shariati, S | 1 |
| Gao, W; Li, W; Xu, J; Xu, S; Yu, Z | 1 |
| Guan, CX; Luo, WJ; Sun, CC; Sun, GY; Tang, CY; Zhang, J; Zhang, YF; Zhou, Y | 1 |
| Alemzadeh, E; Mohammadi, AA; Oryan, A | 1 |
| Huang, W; Kanashiro-Takeuchi, RM; Kazmierczak, K; Liang, J; Szczesna-Cordary, D; Takeuchi, LM; Yadav, S; Yuan, CC | 1 |
| Chen, M; Dong, M; Gao, Y; Han, L; Jin, F; Li, W; Lin, H; Shi, Y; Zhou, Y; Zuo, W | 1 |
| Bahadır, B; Can, M; Kefeli, A; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y | 1 |
| Crowley, SD; Griffiths, R; Gunn, MD; Lu, X; Privratsky, JR; Ren, J; Rudemiller, NP; Wen, Y; Zhang, J | 1 |
| Feng, M; Gao, C; Guo, H; Li, X; Liang, Z; Luo, J; Qin, K; Wang, Y; Zhang, S; Zhao, X | 1 |
| Atamanalp, SS; Donmez, R; Kisaoglu, A; Oren, D; Ozogul, B; Ozturk, G | 1 |
| Khan, A; Khan, SR; Wang, W | 1 |
| Carneiro, FP; Ferreira, VM; Marques e Silva, S; Oliveira, PG; Sousa, JB | 1 |
| Chen, Y; Gao, Y; Gu, Z; Jiang, X; Lu, J; Zhang, Y | 1 |
| Carleton, SM; Kettle, AD; Melander, J; Phillips, CL; Wang, Y; Yao, X | 1 |
| Bai, H; Chen, H; Hai, C; Li, W; Liang, X; Liu, R; Qin, X; Wang, X; Zhang, W; Zhang, X | 1 |
| Bhardwaj, P; Garg, ML; Rai, DV | 1 |
| Fujii, H; Furuya, S; Hara, M; Hirayama, K; Kono, H; Tsuchiya, M | 1 |
| Bian, W; Ding, F; Gu, J; Rong, Z; Shen, C; Xu, L; Yang, D; Zhu, S | 1 |
| Collins, BH; Holzknecht, ZE; Liu, S; Lynn, KA; Parker, W; Rockey, DC; Sempowski, GD; Smith, CC | 1 |
| Chen, D; Feng, Y; Han, X; Jiang, T; Zhou, M | 1 |
| Da Ré Guerra, F; De Almeida, Mdos S; De Aro, AA; De Oliveira, LP; Pimentel, ER; Vieira, CP | 1 |
| Falalieieva, TM; Lazarenko, LM; Neporada, KS; Spivak, MIa; Virchenko, OV | 1 |
| Dong, W; Lv, B; Wei, F; Yang, L | 1 |
| Billings, EM; Fernandez, IE; Gochuico, BR; Goodwin, AJ; Haspel, JA; Kaminski, N; Morse, D; Osorio, JC; Patel, AS; Risquez, CF; Rosas, IO; Ryter, SW; Shi, Y; Tang, X; Wathelet, MG; Yu, G | 1 |
| Camilli, JA; Nakagaki, WR; Pimentel, ER; Tomiosso, TC | 1 |
| Chen, QX; Gao, JQ; Hua, JM; Li, FC; Li, H; Liang, CZ; Peng, LH; Tao, YQ; Wu, JJ | 1 |
| Gautam, MK; Goel, RK; Goel, S; Murthy, S; Purohit, V; Sharma, H | 1 |
| Fu, WW; Liu, CH; Shen, L; Tao, YY; Wang, QL | 1 |
| Li, WY; Wen, KM; Wu, W; Zhang, SH; Zhao, JN | 1 |
| Anthes, JC; Caniga, M; Cicmil, M; Crawley, Y; Fernandez, X; Gil, MA; Jia, Y; Jimenez, J; Kelly, N; Keshwani, S; Klappenbach, J; Lieber, GB; Ma, YL; McLeod, RL; Mingo, GG; Moy, LY; Woodhouse, JD | 1 |
| Meimandi-Parizi, A; Moshiri, A; Oryan, A | 1 |
| Wang, X; Wang, YR; Yang, DY; Zhang, M | 1 |
| Chen, Y; Cheng, QM; Feng, DD; Han, JZ; Huang, YH; Li, C; Li, Y; Liu, W; Luo, ZQ; Wan, J; Yue, SJ | 1 |
| Jian, X; Wang, J; Zhang, W; Zhang, Z; Zhou, Q | 1 |
| Davidson, C; Edukulla, R; Hardie, WD; Ikegami, M; Madala, SK; Schmidt, S | 1 |
| Ardisson, LP; Azevedo, PS; Batista, DF; Gonçalves, AF; Minicucci, MF; Okoshi, K; Paiva, SA; Pereira, EJ; Polegato, BF; Rafacho, BP; Santos, PP; Zornoff, LA | 1 |
| Crenshaw, TD; Nakada, SY; Penniston, KL; Sehgal, PD; Sivalingam, S | 1 |
| Li, Y; Liang, C; Yang, W; Zhang, L | 1 |
| Bratton, DL; Downey, GP; Henson, PM; Janssen, W; Keith, RC; Ortiz, LA; Redente, EF; Riches, DW | 1 |
| Panda, V; Thakur, T | 1 |
| Ahn, CB; Jeong, HW; Jung, WW; Kim, BM; Kim, HS; Kim, KT; Lee, SH; Lee, SK; Park, KY; Son, KH | 1 |
| Ammar, EM; El-Agamy, DS; Sharawy, MH | 1 |
| Fang, X; Gu, J; Gu, P; Qiu, WZ; Yi, XH; Zeng, Y; Zhang, L; Zhang, SX; Zhang, YD; Zhang, ZM; Zhu, XY | 1 |
| Chen, J; Ding, C; Gu, G; Li, J; Ren, J; Wang, G; Wu, Y; Zhou, B | 1 |
| Galanopoulos, G; Kanellos, I; Lazarides, C; Mantzoros, I; Pramateftakis, MG; Raptis, D | 1 |
| Barton, ER; Smith, LR | 1 |
| Joshi, S; Khan, SR; Peck, AB; Wang, W | 1 |
| Cai, J; Chen, H; Feng, X; He, J; Hu, J; Li, X; Liang, Y; Sun, Y; Sun, Z; Wang, J; Xiao, H; Xiong, C; Yan, L; Yu, H | 1 |
| Accart, N; Beckmann, N; Cannet, C; Dunbar, A; Egger, C; Gérard, C; Jarai, G; Jarman, E; Piaia, A; Schmid, HA; Tigani, B; Vidotto, N | 1 |
| Chen, CM; Chen, HL; Cheng, WT; Chong, KY; Tang, TY; Tung, YT; Yang, SH | 1 |
| Chu, D; Yao, Y; Zhou, C | 1 |
| Geisbush, TR; Lachey, J; Li, J; Mulivor, A; Rosen, GD; Rutkove, SB | 1 |
| Kang, JY; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK | 1 |
| Criado, G; Del Rey, MJ; Faré, R; Pablos, JL; Usategui, A | 1 |
| Cherdantseva, LA; Kim, LB; Nikonova, IK; Potapova, OV; Putyatina, AN; Shkurupiy, VA | 1 |
| Batbold, D; Choi, MJ; Kim, WJ; Kwon, KD; Kwon, MH; Park, JM; Ryu, JK; Song, KM; Suh, JK; Yin, GN | 1 |
| Barbas-Filho, JV; Capelozzi, VL; Martins, V; Parra, ER; Pincelli, MS; Rangel, MP; Teodoro, WR; Velosa, AP | 1 |
| Chaturvedi, AA; Hendriks, T; Lomme, RM; van Goor, H | 1 |
| Chen, YH; Cheng, PJ; Cheng, WT; Chou, CJ; Kao, YJ; Ko, IC; Peng, SY; Shaw, SW; Wu, SC | 1 |
| Lu, R; Lv, P; Su, W; Zhang, K; Zhao, J | 1 |
| Fei, GH; Gao, J; Li, LC; Li, P; Qi, LW; Xu, L; Zhao, P | 1 |
| Chau, JK; Chung, M; Frank, CB; Hart, DA; Heard, BJ; Mickiewicz, B; Shrive, NG; Vogel, HJ | 1 |
| Bushman, W; Hutson, PR; Wong, L | 1 |
| Choi, MK; Han, JM; Kim, HG; Kim, JM; Lee, DS; Lee, JS; Park, YH; Son, CG | 1 |
| He, ZY; Lei, L; Sun, XJ; Zhao, C; Zhong, XN | 2 |
| Alabalik, U; Avci, Y; Gül, M; Türkoğlu, A; Ülger, BV; Uslukaya, O; Yuksel, HK | 1 |
| Burkly, LC; Choi, SS; Diehl, AM; Guy, CD; Karaca, G; Krüger, L; Machado, MV; Michelotti, GA; Moylan, C; Swiderska-Syn, M; Xie, G | 1 |
| Sergeev, IN; Song, Q | 1 |
| Gan, Z; Guo, J; Jing, J; Qin, Y; Teng, G; Zhu, G | 1 |
| Abdullah, M; Ho, CC; Koh, RY; Lim, CL; Seow, HF; Uhal, BD; Vidyadaran, S | 1 |
| Bennett, D; Geisbush, T; Greenman, RL; Li, J; Rutkove, SB; Wu, JS | 1 |
| Deng, Z; Gao, J; Li, D; Li, J; Li, L; Li, P; Mo, X; Qi, L; Xu, L; Zhao, P | 1 |
| El Feki, A; Farhat, L; Jebahi, S; Kabir, A; Keskes, H; Oudadesse, H; Rebai, T; Saoudi, M | 1 |
| Chilakapati, DR; Chilakapati, SR; Kanala, JR; Serasanambati, M; Vissavajjhala, P | 1 |
| Ohashi, T; Yamamoto, T | 1 |
| He, ZX; Ma, YQ; Wang, YY; Zhang, CY; Zhe, H; Zhou, SF | 1 |
| Chen, CX; Gao, JP; Gu, WL; Huang, XY | 1 |
| Chen, B; Chen, J; He, W; Qi, L; Shao, D; Wang, L; Wang, M; Zhuang, Y | 1 |
| Jiang, H; Ren, S; Zhang, C; Zhang, J; Zhang, Z | 1 |
| Çikman, Ö; Ercan, U; Karaayvaz, M; Kilinç, N; Kiraz, A; Kiraz, HA; Otkun, MT; Özkan, ÖF; Türkön, H | 1 |
| Feghali-Bostwick, C; Mlakar, L; Nishimoto, T; Takihara, T | 1 |
| Guo, H; Li, X; Song, Y; Wang, L; Zhang, G | 1 |
| Abe, J; Hashimoto, S; Inagaki, Y; Kosugi-Kanaya, M; Matsushima, K; Morikawa, T; Otsuji, M; Shand, FH; Shichino, S; Suzuki, HI; Tsukui, T; Ueha, S | 1 |
| Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK | 1 |
| Cai, Y; Kimura, S | 1 |
| Baba, I; Egi, Y; Suzuki, K | 1 |
| Chen, X; Chen, Y; Lu, Z; Wang, S; Xu, W | 1 |
| Chen, J; Chen, R; Feng, L; Jiang, Z; Li, X; Lou, J; Xia, H; Xiao, Y; Yin, X; Yu, M; Zhang, X; Zhu, L | 1 |
| Buchalski, B; Fargue, S; Fitzgerald, K; Guan, Z; Holmes, RP; Inscho, EW; Knight, J; Li, X; Liebow, A; Querbes, W; Todd Lowther, W | 1 |
| Altenberger, AR; Devor, ST; Lowe, J; Periasamy, M; Rafael-Fortney, JA; Schill, KE; Villamena, FA | 1 |
| Ates, NG; Bozkurt, Y; Cakiroglu, B; Gergerli, R; Piroglu, I; Piroglu, MD; Thomas, DT; Tulgar, S | 1 |
| Bond, CW; Choe, S; Harrington, DA; McVary, KT; Podlasek, CA; Stupp, SI; Veliceasa, D | 1 |
| Cennet, A; Cetinkunar, S; Colak, T; Irkorucu, O; Polat, G; Reyhan, E; Sozutek, A | 1 |
| Bozkırlı, BO; Ersoy, E; Gündoğdu, RH; Temel, H; Yazgan, A; Yıldırım, Z | 1 |
| Kimura, K; Kobayashi, S; Nakamura, Y; Nishida, T; Orita, T; Sonoda, KH; Wada, T; Zhou, H | 1 |
| Zhang, YQ; Zhu, L | 1 |
| Deng, Y; He, J; Liu, X; Lv, L; Rao, J; Wang, W; Yang, G; Yang, Y; Zhang, G; Zhao, X | 1 |
| Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X | 1 |
| Chen, D; Sui, X; Sun, Y; Wang, Y; Zhang, W | 1 |
| Cabral, H; Iwata, C; Kano, MR; Miyazono, K; Morishita, Y; Sakai, S; Tanaka, HY | 1 |
| Dasgupta, SC; Ghosh, S; Gomes, A; Saha, K; Saha, PP | 1 |
| Bartalesi, B; De Cunto, G; Fineschi, S; Galeazzi, M; Garcia Gonzalez, E; Lorenzini, S; Lucattelli, M; Lungarella, G; Selvi, E | 1 |
| Abuelezz, SA; Hendawy, N; Osman, WM | 1 |
| Hammock, BD; Hye Khan, MA; Imig, JD; Lee, KS; Levick, SP; Sharma, A | 1 |
| Debek, W; Hermanowicz, A; Lebensztejn, DM; Miltyk, W; Moczydlowska, J; Palka, JA | 1 |
| Aydogan, C; Bircan, HY; Ekici, Y; Haberal, M; Moray, G; Ozcelik, U; Ozen, O; Turkoglu, S | 1 |
| Liang, Y; Shi, L; Xu, L; Yang, F; Yin, L; Zhang, G; Zhao, F; Zhu, F | 1 |
| Fang, J; Li, Q; Lu, X; Qiu, M; Sun, S; Wang, W; Wang, Y; Zhang, Y | 1 |
| Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA | 1 |
| Nagar, HK; Ranawat, MS; Srivastava, AK; Srivastava, R | 1 |
| Chen, L; Liu, F; Liu, FF; Lu, YQ; Rao, HY; Ren, YY; Teng, X; Wei, L; Wu, N; Zhang, W | 1 |
| Abdel-Sattar, SA; El-Bakly, WM; El-Demerdash, E; Mohamed, EA | 1 |
| Kim, YO; Popov, Y; Schuppan, D | 1 |
| Li, L; Li, Y; Liu, K; Rao, Y; Sui, X; Wu, J; Wu, Q; Zhang, W | 1 |
| Akinyi, TG; Cleveland, ZI; Davidson, CR; Dunn, RS; Guo, J; Hardie, WD; Woods, JC; Zhou, YM | 1 |
| Aoki, K; Fukui, A; Fukunaga, N; Ikebe-Ebata, Y; Kondo, H; Masaki, T; Saito, S; Shinohara, T; Takahashi, N; Teshima, Y | 1 |
| Campos, AD; Feres, O; Ramalho, FS; Ramalho, LN; Rocha, JJ; Veneziano, SG | 1 |
| da Rocha, JJ; Féres, O; Franca, A; Ramalho, FS; Ramalho, LN | 1 |
| Hemmati, AA; Nazari, Z; Samei, M | 1 |
| Chen, J; Chen, Y; Lv, L; Tao, S; Tian, L; Wang, X; Weng, D | 1 |
| Cao, J; Liu, J; Teng, L; Wang, F; Wang, X | 1 |
| Aygen, E; Ayten, R; Cetinkaya, Z; Girgin, M; Ozercan, I; Ustundag, B | 1 |
| Aoyagi, Y; Fukunaga, K; Hashimoto, I; Ikeda, O; Matsuo, R; Murata, S; Nakano, Y; Ohkohchi, N; Watanabe, M; Yasue, H | 1 |
| Barcelos, LS; Costa, LP; Dias, FL; dos Santos, RA; Leite, VH; Oliveira, EA; Pereira, RM; Rezende, AS; Simoes e Silva, AC; Teixeira, MM | 1 |
| Aarts, F; Bleichrodt, RP; Boerman, OC; de Man, B; Hendriks, T; Lomme, R | 1 |
| Aalinkeel, R; Blume, JW; Fang, YV; Knight, PR; Lachina, S; Mahajan, SD; Mullan, BA; Ohtake, PJ; Sands, MF; Schwartz, SA; Sykes, DE; Takyar, SS | 1 |
| Gurung, S; Skalko-Basnet, N | 1 |
| Citgez, B; Isgor, A; Ozcan, O; Ozkaya, O; Polat, N; Uludag, M; Yetkin, G | 2 |
| Gu, ZL; Guo, CY; Sheng, R; Xie, ML; Zhou, WX | 1 |
| Funada, Y; Kobayashi, K; Kono, Y; Kotani, Y; Kuramoto, E; Nishimura, Y; Nishiuma, T; Simon, RH; Sisson, TH; Yamamoto, M | 1 |
| Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS | 1 |
| Cheng, JQ; Cheng, NS; He, S; Jiang, LS; Li, FY; Li, N; Mao, H | 1 |
| Başaklar, AC; Gülbahar, O; Karabulut, R; Poyraz, A; Sancak, B; Sönmez, K; Türkyilmaz, Z | 1 |
| Chen, Y; Wang, X; Weng, D | 1 |
| Gao, S; Long, CL; Wang, H; Wang, RH | 1 |
| Brigham, KL; Gonzalez, ET; Iyer, SS; Kelly, P; Mac, V; Mora, AL; Reed, A; Rojas, M; Sutliff, RL; Xu, J | 1 |
| Bennett, RG; Heimann, DG; Tuma, DJ | 1 |
| Abasiyanik, A; Arbag, H; Cağlayan, O; Oz, M; Yurtçu, M | 1 |
| Chen, D; Chen, Y; Cui, Y; Du, S; Huang, W; Li, H; Li, Y; Wei, Z; Yang, J; Yang, L; Yao, Z; Zhang, R; Zhang, S; Zhou, J | 1 |
| Garrett, MR; Mandel, NS; Roman, RJ; Wiessner, JH | 1 |
| Elliot, SJ; Fritz, JR; Glassberg, MK; Jones, C; Karl, M; Kassira, N; Pincus, DJ; Thaller, S | 1 |
| Bouchier-Hayes, DJ; Condron, C; Moriarty, M; Robb, WB; Walsh, TN | 1 |
| He, CC; Huang, MM; Li, JX; Zhou, XM | 1 |
| Ha, JR; Kim, DH; Kim, DY; Oh, SW | 1 |
| Chen, L; Feng, YL; Huang, XY; Liu, DS; Ou, XM; Uhal, BD; Wang, K; Wang, T; Wang, X; Wen, FQ | 1 |
| Geng, J; Kang, W; Wang, W; Zhang, Y; Zhao, Z; Zhiming, GE | 1 |
| Altinel, O; Ersoz, N; Guven, A; Korkmaz, A; Ozerhan, IH; Ozler, M; Sadir, S; Topal, T; Uysal, B | 1 |
| Hu, MH; Wu, XM; Wu, YH; Zhang, XM; Zhao, Y | 1 |
| Fujita, T | 1 |
| Hou, YH; Pan, JB; Zhang, GJ | 1 |
| Fujibayashi, T; Hasegawa, Y; Hashimoto, N; Ishiguro, N; Jijiwa, M; Kojima, T | 1 |
| French, CJ; Sobel, BE; Zaman, AK | 1 |
| Li, G; Shi, B; Sun, G; Wang, P; Wu, Q; Yin, W; Yu, G | 1 |
| Dong, MX; Geng, YT; Jia, Y; Li, CC; Li, XY; Liu, JC; Niu, YC; Zhang, YB; Zhou, L | 1 |
| Boehler, A; Guo, Z; Hofer, M; Rechsteiner, T; Remund, K | 1 |
| Cho, HY; Kim, HK; Yang, TH | 1 |
| Bi, J; Deng, G; He, G; Luan, Z; Lv, N; Qiao, J; Wang, X; Xu, T; Zhang, M; Zhao, L | 1 |
| Guo, XX; Liang, YJ; Lu, X; Shi, XL; Weng, J; Xu, Q; Zhou, JL | 1 |
| Guo, WD; Shi, SS; Wang, L; Wang, Q; Wu, XR | 1 |
| Ahn, J; Jeon, BJ; Kwak, HS | 1 |
| Chen, J; Chen, Y; Lv, L; Wang, X | 1 |
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| Mowat, AP; Trivedi, P | 1 |
| Counts, DF; Prieur, DJ; Young, DM | 1 |
| Graham, JA; Hatch, GE; Raub, JA | 1 |
| Bashey, RI; Jimenez, SA; Millan, A | 1 |
| Coulais, Y; Cros, J; Guiraud, R; Marcelon, G | 1 |
| Ballardini, G; Bianchi, FB; Biolchini, L; Busachi, CA; de Giorgi, LB; Degli Esposti, S; Faccani, A; Pisi, E | 1 |
| Benveniste, K; Thut, P | 1 |
| Abbott, UK; Benson, DR; Lin, HJ; Riggins, RS; Rucker, RB | 1 |
| Azizkhan, RG; Glick, PL; Karamanoukian, HL; O'Toole, SJ; Rossman, JE; Wilcox, DT | 1 |
| Azizkhan, RG; Glick, PL; Hassett, MJ; Karamanoukian, HL; Rossman, JE; Wilcox, DT | 1 |
| Imakon, Y; Matsubara, H; Nagareda, T; Nishizawa, Y; Noro, A; Shiomi, H; Tanaka, A; Terada, N | 1 |
| Giri, SN; Hyde, DM; Wild, JS | 1 |
| Calvo, JJ; Calvo, OM; del Pino, J; García-Moreno, C; García-Talavera, JR; Herrero, S; Martín, E; Martín, M; San Román, JI; Suquía, B | 1 |
| Araki, T; Ino, H; Mabuchi, H; Shimizu, M; Takeda, R; Yoshio, H | 1 |
| Arlot, ME; Delmas, PD; Meunier, PJ; Nilssen, MH; Pastoureau, P; Vergnaud, P | 1 |
| Aarts, PJ; Arends, JW; Daemen, MJ; Heeneman, S; Leenders, PJ; Smits, JF | 1 |
| Cherniack, RM; Doherty, DE; Hirose, N; Lynch, DA | 1 |
| Andrassy, RJ; Covington, DS; Lally, KP; Pizzini, R; Xue, H | 1 |
| Durbridge, TC; Moore, RJ; Morris, HA; Sims, NA | 2 |
| Hu, H; Stein-Streilein, J | 1 |
| Kayano, K; Kubota, M; Mori, K; Okita, K; Sakaida, I; Takenaka, K | 1 |
| Gelzleichter, TR; Harkema, J; Hawk, S; Last, JA | 1 |
| Brien, JF; Evans, CD; Leeder, RG; Massey, TE | 1 |
| Koopmans, SJ; Löwik, CW; Papapoulos, SE; van der Wee-Pals, L | 1 |
| Attramadal, A; Dahl, E; Gautvik, KM; Gordeladze, JO; Haug, E; Jablonski, G; Klem, KH; Rønningen, H | 1 |
| Bishop, J; Greenham, AK; Lewis, EJ | 1 |
| Gelzleichter, TR; Last, JA; Pinkerton, KE; Walker, RM; Witschi, H | 1 |
| Amento, EP; Bauer, EA; Beck, LS; Keller, G; Lee, WP; Liggitt, HD; Siegel, M; Unemori, EN; Xu, Y | 1 |
| Bocchieri, MH; Christner, PJ; Henriksen, PD; Jimenez, SA | 1 |
| Evans, DM; Guyton, DP; Hawkins, N; McAree, K; Stakleff, K | 1 |
| Ikeda, H; Ishida, H; Koh, G; Kurose, T; Okamoto, Y; Seino, Y; Takeshita, N; Tsuji, K; Yamamoto, T | 1 |
| Colville-Nash, PR; el-Ghazaly, M; Willoughby, DA | 1 |
| Gairola, CG; Lai, YL; Reinhart, PG | 1 |
| Bochenek, A; Machej, L; Pawlak, S; Perlik, T; Radziszewska, E; Skalski, J; Sleczka, B; Wedrychowska, A; Wites, M | 1 |
| Becker, M; Gerling, B; Rehmann, M; Schuppan, D; Waldschmidt, J | 1 |
| Cosso, L; Marinari, UM; Noberasco, G; Odetti, P; Pronzato, MA; Traverso, N | 1 |
| Ahrendt, GM; Barbul, A; Schäffer, MR; Tantry, U; Wasserkrug, HL | 1 |
| Andersen, HR; Baandrup, U; Danielsen, CC; Heickendorff, L; Høst, NB; Klebe, T; Wiggers, H | 1 |
| Booth, R; Gorski, JP; Magnuson, SK; Porter, S | 1 |
| Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Hayes, JA; Robinson, KG; Sen, S | 1 |
| Landis, CA; Whitney, JD | 1 |
| Kiliniç, K; Onol, B; Tahta, K; Turgut, M | 1 |
| Hori, Y; Horie, K; Hoshino, J; Miyauchi, S; Mizuno, S; Sekiguchi, T; Yamazaki, C | 2 |
| Jørgensen, PH | 1 |
| Huang, HF; You, JS | 1 |
| Chen, B; Hou, XM; Jiang, L; Yu, R; Zhao, W | 1 |
| Alam, CA; Greenslade, KJ; Moore, AR; Willoughby, DA | 1 |
| Kajiyama, G; Schurman, DJ; Smith, RL | 1 |
| Harris, A; Messmer, K; Schropp, A | 1 |
| Franco, L; Gomez, BL; Graybill, JR; Najvar, L; Restrepo, A; Restrepo, S | 1 |
| Fukagawa, M; Hata, S; Kuroda, T; Kurokawa, K; Margolin, SB; Shimizu, T | 1 |
| Chandrakasan, G; Punithavathi, D; Venkatesan, N | 1 |
| Bingöl-Kologlu, M; Büyükpamukçu, N; Cakar, N; Hiçsönmez, A; Müftüoğlu, S; Renda, N; Tanyel, FC | 1 |
| Chen, JJ; Curci, JA; Hendricks, RT; Liao, S; Martin, RL; Moore, G; Starcher, BC; Thompson, RW | 1 |
| Kosaka, N; Sugiyama, T; Takashima, M; Uchii, M | 1 |
| Nagahama, M; Natori, J; Shimizu, K; Tanaka, S | 1 |
| Bao, M; Li, D; Li, YM; Song, X | 1 |
| Gertman, PM; Madden, JW; Peacock, EE | 1 |
| Katayama, I; Mizushima, Y; Nishioka, K; Takagawa, S; Yamamoto, T | 1 |
| Katayama, I; Nishioka, K; Takagawa, S; Takahashi, Y; Yamamoto, T | 1 |
| Abe, Y; Hosomi, N; Kimura, S; Kiyomoto, H; Matsuo, H; Mizushige, K; Noma, T; Ohmori, K; Yao, L; Yu, Y | 1 |
| Banerjee, S; Kathayat, R; Malhotra, V; Sarin, SK; Sharma, G | 1 |
| Gupta, A; Jain, GK; Raghubir, R | 1 |
| Baykal, A; Korkmaz, A; Ozdemir, A; Renda, N; Sayek, I | 1 |
| Cho, JJ; Hahn, EG; Herbst, H; Hocher, B; Jia, JD; Riecken, EO; Ruehl, M; Schuppan, D | 1 |
| Rupp, H; Turcani, M | 1 |
| Choi, JH; Kang, HC; Kim, JY; Kim, SJ; Kim, YC; Lee, BH; Lee, JH; Lee, SJ; Nan, JX; Park, EJ; Sohn, DH | 1 |
| Aoshiba, K; Nagai, A; Tamaoki, J; Yasui, S | 1 |
| Giri, SN; Gurujeyalakshmi, G; Wang, Y | 1 |
| Carney, SL | 1 |
| Dohi, M; Hasegawa, T; Marshall, BC; Yamamoto, K | 1 |
| Cui, Y; Petrelli, NJ; Urschel, JD | 1 |
| Banks, DE; Huang, SH; Hubbs, AF; Ma, JK; Rojanasakul, Y; Schnabel, PC; Stanley, CF; Vallyathan, V; Weissman, DN | 1 |
| Iwao, H; Izumi, Y; Kawano, H; Kim, S; Kimoto, M; Yoshiyama, M; Zhan, Y | 1 |
| Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ | 1 |
| Stein-Streilein, J; Sutton, A; Zhang-Hoover, J | 1 |
| Dobashi, K; Horie, T; Iizuka, K; Mori, M; Nakazato, Y; Nakazawa, T; Shimizu, Y; Suzuki, K; Tukagoshi, H | 1 |
| Fukuchi, Y; Ienaga, H; Kon, S; Maeda, K; Maeda, M; Okazaki, T; Takahashi, F; Takahashi, K; Uede, T | 1 |
| Baumann, M; Hirth-Dietrich, C; Pauluhn, J; Rosenbruch, M | 1 |
| Arras, M; Barbarin, V; Coutelier, JP; Delos, M; Huaux, F; Lison, D; Many, MC; Renauld, JC; Vink, A | 1 |
| Eitzman, DT; Shen, YC; Westrick, RJ; Xu, Z | 1 |
| Andrade, ZA; Barbosa, AA; Oliveira, I; Paraná, R; Souza, MM; Trepo, C | 1 |
| Górski, J; Kajdaniuk, D; Kos-Kudla, B; Marek, B; Ostrowska, Z; Swietochowska, E | 1 |
| Hagimoto, N; Hara, N; Kawasaki, M; Kunitake, R; Kuwano, K; Maeyama, T | 1 |
| 't Hart, BA; Bontrop, RE; Brok, HP; De Groot, CW; Hakimi, J; Kerwin, JA; Nijenhuis, EM; Tekoppele, JM | 1 |
| Adachi, Y; Gabazza, EC; Hataji, O; Kobayashi, T; Shimizu, S; Suzuki, K; Taguchi, O; Tamaki, S; Yasui, H; Yuda, H | 1 |
| Castilla-Cortázar, I; García, M; Muguerza, B; Prieto, J; Quiroga, J; Santidrián, S | 1 |
| Hofbauer, A; Messmer, K; Refior, HJ; Veihelmann, A | 1 |
| Appenroth, D; Fleck, C; Kriegsmann, J; Lupp, A; Sawall, S; Sommer, M; Splinther, J; Stein, G | 1 |
| Bean, M; Brenner, MC; Buttrick, PM; Geenen, D; Huang, X; Nwogu, JI | 1 |
| Bailie, M; Marshall, T; Moore, BB; Peters-Golden, M; Phan, SH; Toews, GB; Wilke, C | 1 |
| Cai, WM; Liu, RH; Weng, HL | 1 |
| Chen, W; Chen, X; Lu, S; Shi, J; Xu, W; Yu, M | 1 |
| Alagözlü, H; Candan, F | 1 |
| Aydin, G; Bitiren, M; Demirbilek, S; Vural, H; Yücesan, S | 1 |
| Ciesielska-Kopacz, N; Kajdaniuk, D; Kos-Kudla, B; Marek, B; Ostrowska, Z | 1 |
| Idikio, H; Jugdutt, BI; Kumar, D; Menon, V | 1 |
| Antonini, JM; Hubbs, AF; Reasor, MJ; Roberts, JR; Taylor, MD | 1 |
| Mezey, E; Potter, JJ | 1 |
| Fujimoto, M; Hamaguchi, Y; Hasegawa, M; Kaburagi, Y; Komura, K; Nagaoka, T; Saito, E; Sato, S; Takehara, K; Tedder, TF | 1 |
| Arai, T; Fujiwara, H; Goya, S; Hayashi, S; Kida, H; Matsuoka, H; Mori, M; Morishita, H; Osaki, T; Tachibana, I | 1 |
| Griffin, M; Smith, LL; Wynne, J | 1 |
| Basu, TK; Whitear, SH | 1 |
| Brown, RG; Hoag, GN; Smart, ME; Subden, RE | 1 |
| Frederiksen, DW; Frederiksen, RT; Hoffnung, JM; Williams, RB | 1 |
| Black, HE; Capen, CC; Geho, WB; Potts, JT; Re, R; Yarrington, JT | 1 |
| Allard, R; Berenholc, S; Lamendin, H; Moczar, E; Robert, AM | 1 |
| Fuller, GC; Rodil, JV; Yermakoff, JK | 1 |
| Ito, M; Kohara, U; Suzuki, Y | 1 |
| Kayal, S; Klein, L; Kursh, ED; Persky, L; Schmitt, J | 1 |
| Fischer, JJ; Percarpio, B | 1 |
| Taceva, J | 1 |
| Behrens, F; Mitchell, N; Shepard, N | 1 |
| Piller, NB | 1 |
| Grasedyck, K; Lindner, J | 1 |
| Ancona, D; Crispen, C; Ehrlich, MG; Grossman, A; Jones, H; Mankin, HJ | 1 |
| Kamphausen, U; Paquet, KJ | 1 |
| Black, J; Bora, FW; Lane, JM | 1 |
| Cox, RH; Detweiler, DK; Fischer, GM | 1 |
| Giri, SN; Hyde, DM; Zia, S | 1 |
| Ociepiński, M; Szaflarska-Stojko, E; Zyłka-Włoszczyk, M | 3 |
| Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O | 1 |
| Aita, H; Chaki, K; Hori, Y; Morita, H; Seiki, M; Tagashira, E; Takemasa, T; Ueki, S; Yoneta, T | 1 |
| Altman, RD; Chun, LE; Dean, DD; Eyre, D; Kates, J | 1 |
| Fusamoto, H; Hayashi, N; Imai, Y; Kamada, T; Kasahara, A; Kono, M; Sasaki, Y; Suzuki, K | 1 |
| Axelsson, S; Hjerpe, A; Holmlund, A | 1 |
| Randhawa, AK; Singal, PK | 1 |
| Feng, W; Gold, E; Goulding, A | 1 |
| Asquith, T; Driscoll, KE; Higgins, J; Maurer, JK; Miller, NS; Poynter, J | 1 |
| Aita, H; Chaki, K; Hori, Y; Morita, H; Seiki, M; Seto, K; Tagashira, E; Takemasa, T; Yamada, H; Yoneta, T | 1 |
| Nagai, Y; Nakamura, T; Orimo, H; Suzuki, K; Yamato, H | 1 |
| Kucharz, EI; Olczyk, K; Sonecki, P | 2 |
| Fox, B; Guz, A; Phillips, GJ; Tetley, TD | 1 |
| Alumets, J; Arvidsson, S; Grimelius, L; Haglund, U; Park, PO | 1 |
| Bosma, A; Brouwer, A; Knook, DL; Roholl, PJ; Seifert, WF; Wilson, JH | 1 |
| Olczyk, D; Szaflarska-Stojko, E; Szymczykiewicz, K | 1 |
| Araki, T; Kurimoto, T; Matsuda, K; Omata, T; Tagashira, E; Yamaguchi, I; Yoshida, A | 1 |
| Abbas, HL | 1 |
| Elbadawi, A; Kato, K; Levin, RM; Longhurst, PA; McGuire, EJ; Miller, LF; Radzinski, C; Wein, AJ | 1 |
| Adler, KB; Doherty, J; Hemenway, D; Hill, S; Marsh, JP; Mickey, R; Mossman, BT; Petruska, J; Sesko, A; Shatos, MA | 1 |
| Andrassy, RJ; Black, CT; Hennessey, PJ | 1 |
| Borrelli, J; Frankle, M | 1 |
| Forman, MB; Kolodgie, FD; Osmialowski, AF; Virmani, R | 1 |
| Ching, SV; Fettman, MJ; LeCouteur, RA; Norrdin, RW | 1 |
| Dinges, HP; Redl, H; Schiesser, A; Schlag, G; Thurnher, M | 1 |
| Barton, RM; Chen, HC; Coe, SA; Collopy, PA; Knight, KR; McCann, JJ; O'Brien, BM; Vanderkolk, CA | 1 |
| Harrison, JH; Lazo, JS | 1 |
| Giri, SN; Hyde, DM | 1 |
| Adamson, IY; Bowden, DH; King, GM | 1 |
| Badawy, SB; Barbul, A; Efron, JE; Rotter, SM; Shawe, T; Wasserkrug, HL | 1 |
| Brien, JF; Daniels, JM; Massey, TE | 1 |
| Altman, RD; Dean, DD; Howell, DS; Muniz, OE | 1 |
| Appelman, HD; Hahn, EG; Henley, KS; Kim, KY; Peters, KM; Rush, BD; Ruwart, MJ; Schuppan, D; Vidmar, TJ; Wilkinson, KF | 1 |
| Machnik, F; Müller, A; Schubert, H; Zimmermann, T | 1 |
| Hibbs, MS; Hoidal, JR; Niewoehner, DE; Rao, NV | 1 |
| Capen, CC; Horst, RL; Rosol, TJ; Weisbrode, SE | 1 |
| Broadus, AE; Burtis, WJ; Godsall, JW; Insogna, KL; Stewart, AF | 1 |
| Ambrosio, G; Brigante, F; Cappelli-Bigazzi, M; Chiariello, M; Perrone-Filardi, P; Sifola, C | 1 |
| Flint, MH; Haydock, DA; Hill, GL; Hyde, KF; Poole, CA; Reilly, HC | 1 |
| Durham, SK; Tan, CH; van Rongen, E | 1 |
| Fisch, H; Lipscomb, MF; Stein-Streilein, J; Whitney, PL | 1 |
| Bashey, RI; Fischer, VW; Moore, TL; Osborn, TG | 1 |
| Bowersox, JC | 1 |
| Hackett, RL; Khan, SR | 1 |
| Aznaurian, AV; Beglarian, AG | 1 |
| Gang, NF; Kalant, N | 1 |
| De Haan, BB; Ellis, H; Wilks, M | 1 |
| Bing, OH; Fanburg, BL; Levine, HJ; Matsushita, S | 1 |
| Aschienbrenner, V; Rabinowitz, M; Skosey, JL; Zak, R | 1 |
| Maśliński, C; Religa, Z | 1 |
| Havránková, J; Holusa, R; Kuncová, M; Palecek, F | 1 |
| Connerton, C; Levenson, SM; Levine, N; Seifter, E | 1 |
| Avioli, LV; Russell, JE | 1 |
| Thompson, RC | 1 |
| Hähnel, H; Lindenhayn, K; Mühlbach, R; Schmidt, UJ | 1 |
| Duburque, MT; Melon, JM; Monsaingeon, A; Thomas, E; Thomas, J | 1 |
| Bremmelgaard, A; Dupont, B; Jorgensen, M; Keiding, S; Ranek, L; Thomsen, P; Tyrsted, G | 1 |
| Ehrlich, HP; Grislis, G; Hunt, TK | 1 |
| Black, J; Bora, FW; Heppenstall, RB; Lane, JM; Prockop, DJ | 1 |
| Morgenstern, L; Patin, CS; Sobel, S; Yamakawa, T | 1 |
| Gudbjarnason, S; Mathes, P; Puri, PS | 1 |
| Halme, J; Kahanpää, K; Karhunen, P; Lindy, S; Uitto, J | 1 |
3 review(s) available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Growth hormone, skin and wound healing--experimental studies in the rat.
Topics: Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; Female; Human Growth Hormone; Humans; Hydroxyproline; Proline; Rats; Rats, Wistar; Skin; Wound Healing | 1997 |
Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Animals; Bone Neoplasms; Calcium; Cyclic AMP; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hydroxyproline; Hypercalcemia; Kidney; Neoplasm Proteins; Parathyroid Hormone; Phosphorus; Vitamin D | 1986 |
Calcium oxalate urolithiasis in the rat: is it a model for human stone disease? A review of recent literature.
Topics: Animals; Calcium Oxalate; Diet; Disease Models, Animal; Ethylene Glycols; Female; Foreign Bodies; Glyoxylates; Hydroxyproline; Kidney Tubules, Proximal; Male; Phosphates; Rats; Rats, Inbred Strains; Species Specificity; Uric Acid; Urinary Calculi; Vitamin B 6 Deficiency | 1985 |
1 trial(s) available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis.
Topics: Animals; Antineoplastic Agents; Biopsy; Carbon Tetrachloride; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Hydroxyproline; Interferon-gamma; Liver; Liver Cirrhosis; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2001 |
605 other study(ies) available for hydroxyproline and Disease Models, Animal
| Article | Year |
|---|---|
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Mice; Mice, Inbred C57BL; X-Ray Microtomography | 2022 |
Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis.
Topics: Animals; Cytokines; Diet, High-Fat; Disease Models, Animal; Fructose; Hydroxyproline; Liver; Liver Cirrhosis; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; Non-alcoholic Fatty Liver Disease | 2021 |
Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Ganoderma; Hydroxyproline; Hyperplasia; Inflammation; Leukotriene B4; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2022 |
Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT.
Topics: Animals; Autophagy; Disease Models, Animal; Diterpenes, Kaurane; Hydroxyproline; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred BALB C; NADPH Oxidase 4; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pulmonary Fibrosis | 2022 |
Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptor for Advanced Glycation End Products; Transforming Growth Factor beta | 2022 |
Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis.
Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Disease Models, Animal; Fibrosis; Heparin, Low-Molecular-Weight; Hepatocyte Growth Factor; Hydroxyproline; Interleukin-2; Lung; Mesenchymal Stem Cells; Mice; Organometallic Compounds; Pulmonary Fibrosis; RNA, Messenger; Scleroderma, Systemic; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1 | 2022 |
Effect of intravesical tarantula cubensis extract (Theranekron) on inflammation in an interstitial cystitis rat model.
Topics: Animals; Cystitis; Cystitis, Interstitial; Disease Models, Animal; Female; Hydroxyproline; Inflammation; Interleukin-6; Necrosis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Ulcer | 2023 |
Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin.
Topics: Animals; Bleomycin; Cells, Cultured; Cytoprotection; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Growth Hormone-Releasing Hormone; Hormone Antagonists; Hydroxyproline; Inflammation Mediators; Lung; Male; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; Sermorelin; Signal Transduction | 2019 |
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline; Joint Capsule; Joint Diseases; Male; Muscle Contraction; Myofibroblasts; Rabbits; Stress, Mechanical; Sulfasalazine | 2020 |
[Preventive and therapeutic effects of safflower water extract on systemic scleroderma in mice and its mechanism].
Topics: Animals; Bleomycin; Carthamus tinctorius; Connective Tissue Growth Factor; Disease Models, Animal; Hydroxyproline; Interleukin-17; Interleukin-6; Mice; Mice, Inbred BALB C; Plant Extracts; Random Allocation; Scleroderma, Systemic; Skin; Transforming Growth Factor beta1 | 2019 |
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Disease Models, Animal; Female; Glycolates; Humans; Hydroxyproline; Hyperoxaluria, Primary; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxalates; Oxidoreductases; Proline Oxidase | 2020 |
Effects of thalidomide on Th17, Treg cells and TGF-β1/Smad3 pathway in a mouse model of systemic sclerosis.
Topics: Animals; Cytokines; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Immunosuppressive Agents; Lung; Mice, Inbred BALB C; Phosphorylation; Pulmonary Fibrosis; Scleroderma, Systemic; Signal Transduction; Skin; Smad3 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Thalidomide; Transforming Growth Factor beta1 | 2020 |
Ursodeoxycholic acid alleviates experimental liver fibrosis involving inhibition of autophagy.
Topics: Animals; Autophagy; Blotting, Western; Cell Line; Disease Models, Animal; Humans; Hydroxychloroquine; Hydroxyproline; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1; Ursodeoxycholic Acid | 2020 |
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage.
Topics: Aged; Animals; Behavior, Animal; Cartilage, Articular; Chondrocytes; Collagen Type II; Disease Models, Animal; Gene Expression Regulation; Glycosaminoglycans; Humans; Hydroxyproline; Interleukin-1beta; Knee Joint; Mice, Inbred C57BL; Middle Aged; Osteoarthritis; Pain; Peptides; Signal Transduction | 2020 |
Expression and significance of miR-223 in rats with pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Inflammation; Male; MicroRNAs; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley | 2020 |
Design, synthesis, and biological evaluation of 4-phenoxybenzenesulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Enzyme Assays; Humans; Hydroxamic Acids; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Molecular Docking Simulation; Neoplasms; Proline; Rats; Recombinant Proteins; Sulfones | 2020 |
Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Arterial Pressure; Cardiomyopathies; Collagen; Constriction; Disease Models, Animal; Fibronectins; Fibrosis; Hydroxyproline; Interleukin-11; Male; Mice, Inbred C57BL; Myocardium; Signal Transduction | 2021 |
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Topics: Administration, Oral; Alkalies; Amino Acid Oxidoreductases; Amino Acids; Animals; Bleomycin; Citrus; Collagen Type I; Collagen Type III; Disease Models, Animal; Down-Regulation; Extracellular Matrix Proteins; Hydroxyproline; Mice, Inbred C57BL; Plant Extracts; Protein-Lysine 6-Oxidase; Pulmonary Fibrosis; Smad3 Protein; Transforming Growth Factor beta1 | 2021 |
IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis.
Topics: Aged; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Disease Models, Animal; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Intercellular Signaling Peptides and Proteins; Interleukin-18; Logistic Models; Lung; Male; Mice; Mice, Inbred C57BL; Middle Aged; Prognosis; Proportional Hazards Models | 2021 |
Expression of the α7 Nicotinic Acetylcholine Receptor Is Critically Required for the Antifibrotic Effect of PHA-543613 on Skin Fibrosis.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bleomycin; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Fibrosis; Hydroxyproline; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Quinuclidines; Skin Diseases; Transforming Growth Factor beta1 | 2022 |
The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats.
Topics: Animals; Benzhydryl Compounds; Collagen; Disease Models, Animal; Fibrosis; Glucosides; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Rats, Sprague-Dawley; Smad3 Protein; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Time Factors; Transforming Growth Factor beta1; Ventricular Function, Left | 2021 |
Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat.
Topics: Adiposity; Animals; Antipsychotic Agents; Cardiomegaly; Disease Models, Animal; Female; Haloperidol; Heart Rate; Hydroxyproline; Long QT Syndrome; Myocytes, Cardiac; Natriuretic Peptide, Brain; Obesity; Protein Carbonylation; Rats, Inbred Strains; Risk Assessment; Risk Factors; Time Factors | 2021 |
Reduction of Abdominal Adhesions with Elecrospun Fiber Membranes in Rat Models.
Topics: Animals; Cecum; Chitosan; Disease Models, Animal; Fibrosis; Humans; Hydroxybutyrates; Hydroxyproline; Incidence; Laparotomy; Male; Membranes, Artificial; Polyesters; Polyethylene Glycols; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions | 2018 |
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedgehog Proteins; Hydroxyproline; Liver; Liver Cirrhosis; Mice; Parasite Egg Count; Praziquantel; Pyridines; Schistosoma mansoni; Schistosomiasis mansoni | 2017 |
Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans.
Topics: Actins; Animals; Antioxidants; Bile Ducts; Caffeine; Coffee; Connective Tissue Growth Factor; Disease Models, Animal; Fibrosis; Glutathione Peroxidase; Hepatic Stellate Cells; Hydroxyproline; Lipid Peroxidation; Liver; Liver Cirrhosis, Biliary; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Transforming Growth Factor beta | 2017 |
Total flavonoids of Desmodium styracifolium attenuates the formation of hydroxy-L-proline-induced calcium oxalate urolithiasis in rats.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Fabaceae; Flavonoids; Humans; Hydroxyproline; Kidney; Male; Nephrolithiasis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Elimination | 2018 |
Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Gene Expression Regulation; Glucocorticoids; Hydroxyproline; Inflammation Mediators; Lung; Male; Matrix Metalloproteinase 2; Oxidative Stress; Paraquat; Prednisolone; Pulmonary Fibrosis; Pyridones; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2018 |
Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Burns; Chromones; Diptera; Disease Models, Animal; Escherichia coli; Hydroxyproline; Interleukin-6; Larva; Male; Malondialdehyde; Morpholines; NF-kappa B; Proto-Oncogene Proteins c-akt; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Wound Healing | 2017 |
Effects of vacuum sealing drainage on the treatment of cranial bone-exposed wounds in rabbits.
Topics: Animals; Bandages; Disease Models, Animal; Drainage; Hydroxyproline; Microvessels; Negative-Pressure Wound Therapy; Neovascularization, Physiologic; Rabbits; Skull | 2017 |
Enteral feeding with low-methoxyl pectin accelerates colonic anastomosis healing in rats.
Topics: Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Volatile; Hydrogen-Ion Concentration; Hydroxyproline; Male; Pectins; Rats; Rats, Sprague-Dawley; Serum Albumin; Wound Healing | 2018 |
Effect of Rifaximin on Hepatic Fibrosis in Bile Duct-ligated Rat Model.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Ducts; Bilirubin; Chronic Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Liver Cirrhosis; Male; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Rifamycins; Rifaximin; Tumor Necrosis Factor-alpha | 2017 |
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Topics: Airway Remodeling; Animals; beta Catenin; Disease Models, Animal; Female; Hydroxyproline; Interleukin-6; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred BALB C; MicroRNAs; Pulmonary Fibrosis; Silicon Dioxide; Silicosis; Transforming Growth Factor beta1; Up-Regulation; Wnt Signaling Pathway | 2018 |
Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model.
Topics: Animals; Carnitine O-Palmitoyltransferase; Dietary Proteins; Dietary Sucrose; Disease Models, Animal; Dyslipidemias; Fatty Acids, Nonesterified; Glucose; Hydroxyproline; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Male; Myocardium; PPAR alpha; Rats; Rats, Wistar; Soybean Proteins | 2018 |
The targeted regulation of miR-26a on PTEN-PI3K/AKT signaling pathway in myocardial fibrosis after myocardial infarction.
Topics: Animals; Antagomirs; Cell Differentiation; Disease Models, Animal; Fibroblasts; Hydroxyproline; Male; Matrix Metalloproteinase 9; MicroRNAs; Myocardial Infarction; Myocardium; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction; Up-Regulation | 2018 |
Comparative evaluation of therapeutic efficacy of intra-articular oxaceprol with conventional modalities in osteoarthritis animal model.
Topics: Animals; Antirheumatic Agents; Arthralgia; Cartilage, Articular; Disease Models, Animal; Hydroxyproline; Injections, Intra-Articular; Knee Joint; Male; Osteoarthritis, Knee; Pain Measurement; Rabbits; Random Allocation; Therapeutic Equivalency | 2018 |
Wound healing property of milk in full thickness wound model of rabbit.
Topics: Animals; Cattle; Disease Models, Animal; Hydroxyproline; Male; Milk; Ointments; Phenytoin; Powders; Rabbits; Skin; Wound Healing | 2018 |
Thrombin and factor Xa link the coagulation system with liver fibrosis.
Topics: Actins; Animals; Antithrombins; Blood Coagulation; Cell Line; Cell Shape; Dabigatran; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Gene Expression; Hepatic Stellate Cells; Humans; Hydroxyproline; Liver Cirrhosis; Male; Mice, Inbred C57BL; Procollagen; Receptor, PAR-1; Rivaroxaban; Thrombin; Transforming Growth Factor beta | 2018 |
Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication.
Topics: Acute Lung Injury; Animals; Biomarkers; Cyclophosphamide; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Hydroxyproline; Immunosuppressive Agents; Injections, Intraperitoneal; Lung; Paraquat; Pulmonary Edema; Pulmonary Fibrosis; Pulse Therapy, Drug; Rats, Wistar; Time Factors | 2018 |
Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis.
Topics: Administration, Oral; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydroxyproline; Male; Mice; Nitrosative Stress; Occupational Diseases; Oxidative Stress; Pulmonary Fibrosis; Reproducibility of Results; Silicon Dioxide | 2018 |
Animal Models of Pulmonary Fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Fluorescein-5-isothiocyanate; Histocytochemistry; Hydroxyproline; Mice; Pulmonary Fibrosis | 2018 |
Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway.
Topics: ADAMTS1 Protein; Animals; Antagomirs; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Hydroxyproline; Lung; Male; MicroRNAs; Peptide Fragments; Procollagen; Prodigiosin; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1 | 2018 |
Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress.
Topics: Animals; Apoptosis; Colitis; Dextran Sulfate; Disease Models, Animal; Glycine; Hydroxyproline; Interleukin-6; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Proline; RAW 264.7 Cells; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2018 |
Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxyproline; Leukocytes; Lung; Lung Injury; Lymphocyte Count; Lymphocytes; Male; Mesenchymal Stem Cell Transplantation; Oxidative Stress; Radiation Injuries, Experimental; Random Allocation; Smad2 Protein; Smad3 Protein; Superoxide Dismutase; Time Factors; Transforming Growth Factor beta; Umbilical Cord | 2018 |
Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Coumaric Acids; Disease Models, Animal; Heme Oxygenase-1; Hydroxyproline; Inflammation; Lung; Matrix Metalloproteinase 7; NF-E2-Related Factor 2; NF-kappa B; Organ Size; Oxidative Stress; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta; Weight Gain | 2018 |
Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.
Topics: Animals; Colitis; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Hydroxyproline; Inflammation; Inflammatory Bowel Diseases; Interleukin-10; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL | 2018 |
A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice.
Topics: Actins; Animals; Antibiotics, Antineoplastic; Bleomycin; Bombyx; Connective Tissue Growth Factor; Disease Models, Animal; DNA Damage; Drugs, Chinese Herbal; Ephedra sinica; Fibronectins; Houttuynia; Hydroxyproline; Lung; Malondialdehyde; Medicine, Chinese Traditional; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Prunus armeniaca; Pueraria; Pulmonary Fibrosis; Scutellaria baicalensis | 2018 |
Beneficial contribution of a safflower (Carthamus tinctorius L.) polysaccharide on steroid-induced avascular necrosis of the femoral head in rats.
Topics: Animals; Apoptosis; Carthamus tinctorius; Caspase 3; Disease Models, Animal; Femur Head Necrosis; Hexosamines; Humans; Hydroxyproline; Mice; Osteocytes; Polysaccharides; Rats; Steroids | 2019 |
Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation.
Topics: 3' Untranslated Regions; Animals; Atrial Fibrillation; Cell Proliferation; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Hydroxyproline; Male; MicroRNAs; Myocardium; Proto-Oncogene Proteins c-bcl-6; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2019 |
Epicatechin protective effects on bleomycin-induced pulmonary oxidative stress and fibrosis in mice.
Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Catalase; Catechin; Disease Models, Animal; Glutathione Peroxidase; Hydroxyproline; Inflammation; Lung; Male; Malondialdehyde; Mice; Oxidative Stress; Protective Agents; Pulmonary Fibrosis; Superoxide Dismutase | 2019 |
Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Anticoagulants; Bleomycin; Dermatan Sulfate; Disease Models, Animal; Female; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis | 2019 |
Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C.
Topics: Actins; Animals; Collagen Type III; Disease Models, Animal; Fibroblasts; Hydroxyproline; Lipopolysaccharides; Male; Mice; NIH 3T3 Cells; Protein Kinase Inhibitors; Receptors, Interleukin; Receptors, Interleukin-17; Respiratory Distress Syndrome; Signal Transduction; Vasoactive Intestinal Peptide | 2019 |
Hyaluronic acid hydrogel loaded by adipose stem cells enhances wound healing by modulating IL-1β, TGF-β1, and bFGF in burn wound model in rat.
Topics: Acellular Dermis; Adipocytes; Animals; Burns; Disease Models, Animal; Drug Carriers; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Hyaluronic Acid; Hydrogels; Hydroxyproline; Interleukin-1beta; Rats; Sheep; Skin; Stem Cell Transplantation; Stem Cells; Transforming Growth Factor beta1; Wound Healing | 2020 |
Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM.
Topics: Animals; Cardiomyopathy, Hypertrophic, Familial; Dependovirus; Disease Models, Animal; Echocardiography; Female; Fibrosis; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; HEK293 Cells; Hemodynamics; Humans; Hydroxyproline; Male; Mice; Muscle Contraction; Muscles; Myosin Light Chains | 2019 |
Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Female; Fluorescent Antibody Technique; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Stem Cells | 2019 |
The protective and anti-inflammatory effect of methylene blue in corrosive esophageal burns: An experimental study.
Topics: Animals; Anti-Inflammatory Agents; Burns, Chemical; Caustics; Disease Models, Animal; Enzyme Inhibitors; Esophageal Stenosis; Esophagus; Hydroxyproline; Methylene Blue; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2019 |
Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis
Topics: Actins; Animals; Benzofurans; Collagen Type I; CX3C Chemokine Receptor 1; Disease Models, Animal; Extracellular Matrix; Fibrosis; Gene Expression; Hydroxyproline; Kidney; Kidney Diseases; Macrophages; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Mice; Morpholines; Myeloid Cells; Twist-Related Protein 1; Ureteral Obstruction | 2019 |
Metformin attenuates bleomycin-induced scleroderma by regulating the balance of Treg/Teff cells and reducing spleen germinal center formation.
Topics: Animals; Bleomycin; Cell Differentiation; Collagen; Disease Models, Animal; Female; Fibrosis; Germinal Center; Hydroxyproline; Interleukin-17; Metformin; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 3; Skin; Skin Diseases; Spleen; T-Lymphocytes, Regulatory; Th17 Cells | 2019 |
The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model.
Topics: Administration, Oral; Anastomosis, Surgical; Animals; Disease Models, Animal; Drug Therapy, Combination; Glutamine; Growth Hormone; Hydroxyproline; Injections, Subcutaneous; Intestinal Mucosa; Intestines; Intraabdominal Infections; Male; Postoperative Complications; Rats; Rats, Sprague-Dawley; Sepsis; Wound Healing | 2013 |
Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys.
Topics: Animals; Calcium Oxalate; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Durapatite; Epithelial Cells; Extracellular Matrix Proteins; Hydroxyproline; Hyperoxaluria; Kidney; Madin Darby Canine Kidney Cells; Male; Matrix Gla Protein; Nephrolithiasis; Oxalates; Rats; Rats, Sprague-Dawley; Time Factors | 2014 |
Effects of metoclopramide on healing of colonic anastomoses in a rat model of abdominal sepsis.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Hydroxyproline; Ligation; Male; Metoclopramide; Punctures; Rats; Rats, Wistar; Sepsis; Tensile Strength; Tissue Adhesions; Wound Healing | 2013 |
Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21.
Topics: Actins; Administration, Oral; Animals; Antioxidants; Bleomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Hydroxyproline; Male; MicroRNAs; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2013 |
Gender-dependence of bone structure and properties in adult osteogenesis imperfecta murine model.
Topics: Animals; Biomechanical Phenomena; Carbonates; Disease Models, Animal; Elastic Modulus; Female; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Osteogenesis; Osteogenesis Imperfecta; Phosphates; Sex Factors; Spectrum Analysis, Raman; Tibia; X-Ray Microtomography | 2013 |
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Gene Silencing; Hydroxyproline; Intubation, Intratracheal; Lipid Peroxidation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Pulmonary Fibrosis; Reactive Oxygen Species | 2013 |
Zinc as a nutritional approach to bone loss prevention in an ovariectomized rat model.
Topics: Animals; Catalase; Disease Models, Animal; Female; Glutathione; Humans; Hydroxyproline; Osteoporosis, Postmenopausal; Ovariectomy; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Trace Elements; Zinc | 2013 |
Interleukin-17A plays a pivotal role in cholestatic liver fibrosis in mice.
Topics: Actins; Animals; Cells, Cultured; Collagen Type I; Disease Models, Animal; Hepatic Stellate Cells; Hydroxyproline; In Vitro Techniques; Interleukin-17; Kupffer Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2013 |
Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6.
Topics: Alveolar Epithelial Cells; Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Cytokines; Disease Models, Animal; Gene Expression; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Mucin-1; Pulmonary Fibrosis; Specific Pathogen-Free Organisms | 2013 |
Association of age-dependent liver injury and fibrosis with immune cell populations.
Topics: Age Factors; Aging; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen Type I; Collagen Type I, alpha 1 Chain; Cytokines; Disease Models, Animal; Fibronectins; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lymphocyte Subsets; Macrophages; Male; Mice; Mice, Inbred BALB C; RNA, Messenger | 2013 |
[Monoclonal antibody against laminin receptor 1 inhibits the pulmonary fibrosis induced by bleomycin in rats].
Topics: Animals; Antibodies, Monoclonal; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Matrix Metalloproteinase 9; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein A; Rats; Receptors, Laminin; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2013 |
Inflammatory process induced by carrageenan in adjacent tissue triggers the acute inflammation in deep digital flexor tendon of rats.
Topics: Animals; Carrageenan; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Hydroxyproline; Inflammation; Male; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Tendinopathy; Time Factors | 2013 |
[Prophylactic effect of probiotic strains Bifidobacterium animalis VKL and VKB on stress-induced lesions in the gastric mucosa of rats].
Topics: Animals; Bifidobacterium; Dietary Supplements; Disease Models, Animal; Female; Food Deprivation; Fructose; Gastric Mucosa; Hexuronic Acids; Hydroxyproline; Probiotics; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 2013 |
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats.
Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Cytoprotection; Disease Models, Animal; Fatty Liver; Hydroxyproline; Inflammation Mediators; Interleukin-1beta; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Protective Agents; Rats; Rats, Wistar; Recombinant Proteins; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta | 2013 |
Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.
Topics: Animals; Apoptosis; Bleomycin; Bronchoalveolar Lavage; Caveolin 1; Disease Models, Animal; Gene Expression Profiling; Genetic Markers; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; In Vitro Techniques; Macrophages, Alveolar; Mice; Mice, Transgenic; Signal Transduction; Syndecan-2; Tissue Array Analysis; Transforming Growth Factor beta1; Up-Regulation | 2013 |
Mechanical and morphological aspects of the calcaneal tendon of mdx mice at 21 days of age.
Topics: Animals; Biomechanical Phenomena; Calcaneus; Disease Models, Animal; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophies; Stress, Mechanical; Tendons; Tensile Strength | 2013 |
Dual release of dexamethasone and TGF-β3 from polymeric microspheres for stem cell matrix accumulation in a rat disc degeneration model.
Topics: Adipose Tissue; Animals; Cell Differentiation; Dexamethasone; Disease Models, Animal; Gene Expression Regulation; Glycosaminoglycans; Heparin; Humans; Hydrodynamics; Hydroxyproline; Immunohistochemistry; Intervertebral Disc Degeneration; Magnetic Resonance Imaging; Microspheres; Nanoparticles; Polyglactin 910; Radiography; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Transforming Growth Factor beta3; Water | 2013 |
Evaluation of in vivo wound healing activity of Bacopa monniera on different wound model in rats.
Topics: Animals; Antioxidants; Bacopa; Bacteria; Disease Models, Animal; Free Radicals; Granulation Tissue; Hexosamines; Hexuronic Acids; Hydroxyproline; Microbial Sensitivity Tests; Peroxidase; Phytotherapy; Plant Extracts; Rats; Skin; Vitamin E; Wound Healing; Wounds and Injuries | 2013 |
Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro.
Topics: Animals; Benzofurans; Cell Proliferation; Collagen Type I; Disease Models, Animal; Hepatic Stellate Cells; Hydroxyproline; Liver Cirrhosis; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2013 |
Efficacy of HGF carried by ultrasound microbubble-cationic nano-liposomes complex for treating hepatic fibrosis in a bile duct ligation rat model, and its relationship with the diffusion-weighted MRI parameters.
Topics: Animals; Common Bile Duct; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Drug Carriers; Echo-Planar Imaging; Gene Transfer Techniques; Genetic Therapy; Hepatocyte Growth Factor; Hydroxyproline; Ligation; Liposomes; Liver; Liver Cirrhosis; Male; Microbubbles; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sonication; Ultrasonography | 2013 |
Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models.
Topics: Animals; Bleomycin; Disease Models, Animal; Elasticity; Fibrosis; Hydroxyproline; Hypersensitivity; Lipopolysaccharides; Lung; Male; Mice; Mineralocorticoid Receptor Antagonists; Pneumonia; Pulmonary Ventilation; Rats; Receptors, Mineralocorticoid | 2013 |
Tendon tissue engineering and its role on healing of the experimentally induced large tendon defect model in rabbits: a comprehensive in vivo study.
Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; Hydroxyproline; Male; Platelet-Derived Growth Factor; Rabbits; Tendon Injuries; Time Factors; Tissue Engineering; Tissue Scaffolds; Wound Healing | 2013 |
[The inhibitory effect of latent transforming growth factor β1 activation and silicosis by CD36 targeted RNA interference in silicosis model of rat].
Topics: Animals; Bronchoalveolar Lavage Fluid; CD36 Antigens; Disease Models, Animal; Female; Hydroxyproline; Macrophages, Alveolar; Male; Rats; Rats, Wistar; RNA Interference; Silicon Dioxide; Silicosis; Transforming Growth Factor beta1 | 2013 |
Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Cell Proliferation; Disease Models, Animal; Fibroblasts; Hydroxyproline; In Vitro Techniques; Interleukin-1beta; Lung; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Peptide Fragments; Pulmonary Fibrosis; Transforming Growth Factor beta1; Treatment Outcome; Tumor Necrosis Factor-alpha; Uteroglobin | 2013 |
Using bosentan to treat paraquat poisoning-induced acute lung injury in rats.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bosentan; Disease Models, Animal; Endothelin-1; Hydroxyproline; Male; Paraquat; Rats; Rats, Wistar; Sulfonamides; Transforming Growth Factor beta1 | 2013 |
Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.
Topics: Adoptive Transfer; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Cell Proliferation; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Disease Progression; Fibroblasts; Genes, Reporter; Green Fluorescent Proteins; Hyaluronan Receptors; Hydroxyproline; Lung; Mice; Mice, Transgenic; Pulmonary Fibrosis; Stromal Cells; Time Factors; Transforming Growth Factor alpha; Up-Regulation | 2014 |
Periostin as a modulator of chronic cardiac remodeling after myocardial infarction.
Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Collagen Type I; Collagen Type III; Diastole; Disease Models, Animal; Hydroxyproline; Male; Myocardial Infarction; Rats; Rats, Wistar; Systole; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2013 |
Dietary hydroxyproline induced calcium oxalate lithiasis and associated renal injury in the porcine model.
Topics: Animal Feed; Animals; Calcium Oxalate; Diet; Disease Models, Animal; Female; Hydroxyproline; Hyperoxaluria; Kidney Calculi; Kidney Tubules, Collecting; Swine | 2013 |
CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis.
Topics: Actins; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; CCN Intercellular Signaling Proteins; Cell Proliferation; Cell Survival; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Mice; Phenotype; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; Repressor Proteins; Signal Transduction; Transforming Growth Factor beta1 | 2014 |
Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; fas Receptor; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Lung Compliance; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Receptor, Macrophage Colony-Stimulating Factor; Recovery of Function; Remission Induction; Tacrolimus Binding Proteins; Time Factors; Tumor Necrosis Factor-alpha | 2014 |
Wound healing activity of the inflorescence of Typha elephantina (Cattail).
Topics: Administration, Topical; Animals; Bandages; Disease Models, Animal; Female; Free Radical Scavengers; Gels; Hexosamines; Hydroxyproline; Inflorescence; Lipid Peroxidation; Male; Phytotherapy; Plant Extracts; Plant Preparations; Rats; Rats, Wistar; Skin; Typhaceae; Wound Healing; Wounds and Injuries | 2014 |
The use of collagen content as determined by spectral domain polarization-sensitive optical coherence tomography to assess colon anastomosis healing in a rat model.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Antineoplastic Agents; Collagen; Collagen Type I; Collagen Type III; Colon; Disease Models, Animal; Fluorouracil; Hydroxyproline; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tomography, Optical Coherence; Wound Healing | 2014 |
Agmatine attenuates silica-induced pulmonary fibrosis.
Topics: Agmatine; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Glutathione; Hydroxyproline; Lipid Peroxidation; Lung; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pneumonia; Pulmonary Edema; Pulmonary Fibrosis; Rats, Sprague-Dawley; Silicon Dioxide; Superoxide Dismutase; Time Factors | 2014 |
[Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice].
Topics: Actins; Animals; Bleomycin; Calcitriol; Collagen Type I; Disease Models, Animal; Gene Expression Regulation; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wnt Signaling Pathway | 2013 |
Protection of colonic anastomosis with platelet-rich plasma gel in the open abdomen.
Topics: Abdomen; Abdominal Wound Closure Techniques; Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Gels; Hydroxyproline; Male; Platelet-Rich Plasma; Pressure; Rats; Rats, Sprague-Dawley; Tensile Strength; Tissue Adhesives; Wound Healing | 2014 |
The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions.
Topics: Anastomosis, Surgical; Animals; Body Weight; Collagenases; Colon; Disease Models, Animal; Hydroxyproline; Ileus; Iloprost; Injections, Intraperitoneal; Male; Pressure; Random Allocation; Rats; Surgical Wound Dehiscence; Tissue Adhesions; Vasodilator Agents; Wound Healing | 2014 |
Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.
Topics: Animals; Biomechanical Phenomena; Collagen; Diaphragm; Disease Models, Animal; Elasticity; Extracellular Matrix; Fibrosis; Hydroxyproline; Male; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Protein Conformation; Protein Processing, Post-Translational; Viscosity | 2014 |
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.
Topics: Acetophenones; Animals; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hyperoxaluria; Kidney; Kidney Calculi; Male; Rats; Reactive Oxygen Species | 2014 |
The optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Disease Models, Animal; Femur; Hydroxyproline; Male; Patellofemoral Joint; Rabbits; Random Allocation; Tissue Adhesions | 2014 |
Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
Topics: Animals; Bleomycin; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Inflammation; Lung; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Somatostatin | 2014 |
Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation.
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Hydroxyproline; Lactoferrin; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ultrasonography | 2014 |
The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factors; Extracellular Matrix Proteins; Female; Granuloma; Hydroxyproline; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Liver Diseases; Lung; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Random Allocation; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Schistosomiasis japonica; Signal Transduction; Smad Proteins; STAT6 Transcription Factor; Transforming Growth Factor beta | 2014 |
Electrical impedance myography for the in vivo and ex vivo assessment of muscular dystrophy (mdx) mouse muscle.
Topics: Age Factors; Animals; Biomarkers; Disease Models, Animal; Electric Impedance; Electromyography; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophies | 2014 |
Effect of nilotinib on airway remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Chronic Disease; Disease Models, Animal; Female; Hydroxyproline; Mice; Mice, Inbred BALB C; Mucin 5AC; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta | 2014 |
Topical vitamin D analogue calcipotriol reduces skin fibrosis in experimental scleroderma.
Topics: Administration, Topical; Animals; Bleomycin; Calcitriol; Collagen; Cytokines; Dermatologic Agents; Disease Models, Animal; Female; Fibrosis; Humans; Hydroxyproline; Interleukin-13; Mice; Mice, Inbred C3H; Scleroderma, Systemic; Skin; Thymic Stromal Lymphopoietin; Up-Regulation | 2014 |
Fibrogenesis in granulomas and lung interstitium in tuberculous inflammation in mice.
Topics: Animals; BCG Vaccine; Cell Proliferation; Disease Models, Animal; Fibroblasts; Granuloma; Hydroxyproline; Inflammation; Lung; Macrophages; Male; Mice; Mice, Inbred BALB C; Mycobacterium bovis; Pulmonary Fibrosis; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha | 2014 |
Silencing histone deacetylase 2 using small hairpin RNA induces regression of fibrotic plaque in a rat model of Peyronie's disease.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Histone Deacetylase 2; Humans; Hydroxyproline; Inflammation; Male; Penile Induration; Rats; RNA Interference; RNA, Small Interfering; Smad3 Protein; Transfection | 2014 |
Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia.
Topics: Animals; Apoptosis; Butylated Hydroxytoluene; Cell Proliferation; Collagen Type I; Collagen Type II; Collagen Type V; Disease Models, Animal; Epithelial Cells; Fibroblasts; Fluorescent Antibody Technique; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice, Inbred BALB C; Microscopy, Electron; Pulmonary Alveoli; Pulmonary Fibrosis; Staining and Labeling; Telomerase | 2014 |
Ultrapure alginate anti-adhesion gel does not impair colon anastomotic strength.
Topics: Abdominal Abscess; Alginates; Anastomosis, Surgical; Animals; Biocompatible Materials; Collagen; Colon; Disease Models, Animal; Gels; Glucuronic Acid; Hexuronic Acids; Hydroxyproline; Male; Postoperative Period; Pressure; Random Allocation; Rats, Wistar; Tissue Adhesions; Wound Healing | 2014 |
Therapeutic potential of amniotic-fluid-derived stem cells on liver fibrosis model in mice.
Topics: Alanine Transaminase; Amniotic Fluid; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Disease Models, Animal; Fetal Stem Cells; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Serum Albumin | 2014 |
Immunomodulatory effectiveness of licofelone in preventing epidural fibrosis in post-laminectomy rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cicatrix; Disease Models, Animal; Double-Blind Method; Epidural Space; Failed Back Surgery Syndrome; Fibrosis; Gene Expression; Hydroxyproline; Interleukin-6; Laminectomy; Lumbar Vertebrae; Male; Pyrroles; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Tissue Adhesions; Transforming Growth Factor beta1 | 2015 |
Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Collagen Type I; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Lung; Polysaccharides; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2014 |
Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament Reconstruction; Asparagine; Biomarkers; Disease Models, Animal; Female; Glucose; Hydroxyproline; Isobutyrates; Knee Joint; Magnetic Resonance Spectroscopy; Metabolome; Osteoarthritis, Knee; Serine; Sheep; Synovial Fluid; Uridine | 2015 |
Resolution of chronic bacterial-induced prostatic inflammation reverses established fibrosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Enrofloxacin; Escherichia coli Infections; Fibrosis; Fluoroquinolones; Hydroxyproline; Male; Mice, Inbred C3H; Prostate; Prostatitis | 2015 |
Chunggan extract, a traditional herbal formula, ameliorated alcohol-induced hepatic injury in rat model.
Topics: Animals; Cell Line; Collagen; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Hepatocytes; Hydroxyproline; Liver; Liver Diseases, Alcoholic; Male; Malondialdehyde; Phytotherapy; Plants, Medicinal; Protective Agents; Proto-Oncogene Proteins c-sis; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transforming Growth Factor beta | 2014 |
IL-21 induction of CD4+ T cell differentiation into Th17 cells contributes to bleomycin-induced fibrosis in mice.
Topics: Animals; Bleomycin; CD4-Positive T-Lymphocytes; Cell Differentiation; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Interleukin-17; Interleukins; Lung; Mice; Mice, Inbred BALB C; Recombinant Proteins; Scleroderma, Systemic; Skin; Th17 Cells; Up-Regulation | 2015 |
Effect of intraperitoneal curcumin instillation on postoperative peritoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Curcumin; Disease Models, Animal; Hydroxyproline; Infusions, Parenteral; Male; Peritoneum; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Tissue Adhesions | 2015 |
Role of Fn14 in acute alcoholic steatohepatitis in mice.
Topics: Acute Disease; Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Ethanol; Fatty Liver, Alcoholic; Hydroxyproline; Inflammation Mediators; Liver; Liver Cirrhosis, Alcoholic; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, Tumor Necrosis Factor; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; TWEAK Receptor; Wound Healing | 2015 |
High vitamin D and calcium intakes increase bone mineral (Ca and P) content in high-fat diet-induced obese mice.
Topics: Animals; Bone and Bones; Calcium; Calcium, Dietary; Cholecalciferol; Diet, High-Fat; Disease Models, Animal; Drug Therapy, Combination; Hydroxyproline; Male; Mice; Obesity; Osteocalcin; Parathyroid Hormone; Phosphorus; Treatment Outcome; Vitamin D | 2015 |
Preventive effects of ¹²⁵I seeds on benign restenosis following esophageal stent implantation in a dog model.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Disease Models, Animal; Dogs; Esophageal Stenosis; Female; Fibroblasts; Hydroxyproline; Iodine Radioisotopes; Male; Recurrence; Stents | 2015 |
Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.
Topics: Animals; Bleomycin; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Drug Eruptions; Female; Fibrosis; Hydroxyproline; Interleukin-17; Interleukin-21 Receptor alpha Subunit; Interleukins; Lung; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Phenotype; Pneumonia; Pulmonary Fibrosis; Scleroderma, Systemic; Skin; Spleen; Th17 Cells; Up-Regulation | 2016 |
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis.
Topics: Actins; Animals; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Dioxoles; Disease Models, Animal; Female; Fibroblasts; Humans; Hydroxyproline; Mice; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta | 2015 |
Assessment of aged mdx mice by electrical impedance myography and magnetic resonance imaging.
Topics: Animals; Disease Models, Animal; Electric Impedance; Hydroxyproline; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle Strength; Muscle, Skeletal; Muscular Dystrophies; Myography; Statistics, Nonparametric | 2015 |
Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Actins; Animals; Bleomycin; Collagen Type I; Disease Models, Animal; Drugs, Chinese Herbal; Female; HMGB1 Protein; Hydroxyproline; Lung; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2015 |
Effect of novel curcumin-encapsulated chitosan-bioglass drug on bone and skin repair after gamma radiation: experimental study on a Wistar rat model.
Topics: Animals; Bone and Bones; Ceramics; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Female; Free Radical Scavengers; Gamma Rays; Hydroxyproline; Inflammation Mediators; Rats; Rats, Wistar; Skin; Staphylococcus aureus; Whole-Body Irradiation; Wound Healing | 2015 |
Amelioration of bleomycin-induced pulmonary fibrosis in a mouse model by a combination therapy of bosentan and imatinib.
Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Bosentan; Catalase; Collagen Type I; Collagen Type II; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Oxidative Stress; Peroxidase; Pneumonia; Pulmonary Edema; RNA, Messenger; Sulfonamides; Superoxide Dismutase; Time Factors | 2015 |
Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.
Topics: Animals; Bleomycin; Cell Count; Chemokine CCL3; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Interferon-gamma; Isoxazoles; Lung; Mast Cells; Mice; Propionates; Receptors, Lysophosphatidic Acid; RNA, Messenger; Scleroderma, Systemic; Skin; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2015 |
Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen; Cytokines; Cytoprotection; Disease Models, Animal; Female; Gene Expression Regulation; Hydroxyproline; Inflammation Mediators; Lung; Lung Injury; Mice, Inbred C57BL; Oleanolic Acid; Pulmonary Fibrosis; Radiation Pneumonitis; RNA, Messenger | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Coumaric Acids; Disease Models, Animal; Endothelin-1; Heart; Heart Rate; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Scrophularia; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trisaccharides; Ventricular Remodeling | 2015 |
Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Disease Models, Animal; Diterpenes; HSP70 Heat-Shock Proteins; Hydroxyproline; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Up-Regulation | 2015 |
Effect of transplanted adipose‑derived stem cells in mice exhibiting idiopathic pulmonary fibrosis.
Topics: Adipose Tissue; Alveolar Epithelial Cells; Animals; Apoptosis; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Stem Cell Transplantation; Stem Cells | 2015 |
The Effect of Systemic Carnitine Administration on Colon Anastomosis Healing in an Experimental Sepsis Model.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Carnitine; Colon; Disease Models, Animal; Hydroxyproline; Injections, Intraperitoneal; Pressure; Rats; Rats, Sprague-Dawley; Sepsis; Wound Healing | 2015 |
An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Disease Models, Animal; Endostatins; Humans; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Pulmonary Fibrosis | 2015 |
Role of thioredoxin nitration in bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Male; Nitrates; Oxidation-Reduction; Pulmonary Fibrosis; Rats; Rats, Wistar; Thioredoxins; Tyrosine | 2016 |
Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Epithelial Cells; Gene Expression Profiling; Humans; Hydroxyproline; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Monocytes; Oligonucleotide Array Sequence Analysis; Pulmonary Fibrosis; Receptors, CCR2; Silicon Dioxide | 2015 |
Effect of roflumilast on airway remodelling in a murine model of chronic asthma.
Topics: Airway Remodeling; Allergens; Aminopyridines; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Chronic Disease; Cyclopropanes; Cytokines; Disease Models, Animal; Female; Goblet Cells; Humans; Hydroxyproline; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Respiratory Hypersensitivity; T-Lymphocyte Subsets | 2016 |
Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Collectins; Cytokines; Disease Models, Animal; Hydroxyproline; Inflammation; Interleukin-4; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Real-Time Polymerase Chain Reaction; RNA, Messenger; Secretoglobins; Severity of Illness Index; Transforming Growth Factor beta | 2015 |
Partial deletion of the ROCK2 protein fails to reduce renal fibrosis in a unilateral ureteral obstruction model in mice.
Topics: Animals; Collagen Type I; Disease Models, Animal; Fibrosis; Gene Deletion; Heterozygote; Hydroxyproline; Kidney; Male; Mice, Knockout; rho-Associated Kinases; RNA, Messenger; Transforming Growth Factor beta1; Ureteral Obstruction | 2016 |
[Effect of edaravone on oxidative stress and myocardial fibrosis induced by isoproterenol in rats].
Topics: Animals; Antipyrine; Cardiomyopathies; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Edaravone; Heart; Hydroxyproline; Isoproterenol; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta1 | 2015 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleukin-6; Lung; Malondialdehyde; Pulmonary Fibrosis; Quartz; Rats; Rats, Wistar; Silicon Dioxide; Silicosis; Tumor Necrosis Factor-alpha | 2015 |
Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Disease Models, Animal; Hydroxyproline; Hyperoxaluria, Primary; Liver; Male; Mice; Mice, Inbred C57BL; Oxalates; Proline Oxidase; RNA, Small Interfering; RNAi Therapeutics | 2016 |
Muscle damage, metabolism, and oxidative stress in mdx mice: Impact of aerobic running.
Topics: Animals; Collagen; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Glutathione; Glutathione Disulfide; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myofibrils; Oxidative Stress; Oxygen Consumption; Physical Conditioning, Animal | 2016 |
Mechanical Bowel Preparation Does Not Affect Anastomosis Healing in an Experimental Rat Model.
Topics: Anastomosis, Surgical; Animals; Cathartics; Colectomy; Colon; Disease Models, Animal; Hydroxyproline; Phosphates; Postoperative Period; Pressure; Random Allocation; Rats; Rats, Wistar; Wound Healing | 2016 |
Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction.
Topics: Animals; Collagen; Diabetes Mellitus; Disease Models, Animal; Drug Delivery Systems; Erectile Dysfunction; Fibrosis; Ganglia; Hedgehog Proteins; Humans; Hydrogels; Hydroxyproline; Immunohistochemistry; Male; Nanofibers; Penis; Peptides; Prostatectomy; Rats, Sprague-Dawley; Staining and Labeling; Time Factors | 2016 |
The Effect of Platelet-Rich-Plasma on the Healing of Left Colonic Anastomosis in a Rat Model of Intra-Abdominal Sepsis.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Growth Substances; Hydroxyproline; Male; Platelet-Rich Plasma; Rats; Rats, Wistar; Sepsis; Wound Healing | 2016 |
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats, Wistar; Valerates; Wound Healing | 2017 |
Inhibition by all-trans retinoic acid of collagen degradation mediated by corneal fibroblasts.
Topics: Animals; Cells, Cultured; Collagen; Corneal Keratocytes; Corneal Ulcer; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; I-kappa B Proteins; Immunoblotting; Immunoenzyme Techniques; Interleukin-1beta; Keratolytic Agents; Lipopolysaccharides; Male; Matrix Metalloproteinases; NF-kappa B; Phosphorylation; Rabbits; Tretinoin | 2016 |
Postoperative anti-adhesion ability of a novel carboxymethyl chitosan from silkworm pupa in a rat cecal abrasion model.
Topics: Animals; Bombyx; Cecum; Chitosan; Cytokines; Disease Models, Animal; Hydroxyproline; Leukocytes; Male; Pupa; Rats; Rats, Sprague-Dawley; Tissue Adhesions | 2016 |
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Topics: Animals; Blood Pressure; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Endomyocardial Fibrosis; Hydroxyproline; Hypertension; Male; Rats; Rats, Inbred WKY; Transforming Growth Factor beta | 2016 |
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats.
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Cross-Sectional Studies; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hypertension; Immunohistochemistry; Male; Myocardium; NF-kappa B; Osteoprotegerin; RANK Ligand; Rats, Inbred SHR; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome; Ventricular Function, Left | 2016 |
In Vivo Wound Healing Studies.
Topics: Administration, Cutaneous; Animals; Biomarkers; Bioprospecting; Disease Models, Animal; Drug Discovery; Female; Hydroxyproline; Male; Ointments; Phytochemicals; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Skin; Wound Healing; Wounds, Penetrating | 2016 |
Effects of chitin and sepia ink hybrid sponge on the healing of burning wound rats and its impact on macrophages in vitro.
Topics: Animals; Burns, Chemical; Chitin; Cytokines; Disease Models, Animal; Hydroxyproline; Ink; Macrophages; Male; Matrix Metalloproteinase 1; Phagocytosis; Random Allocation; Rats, Wistar; Sepia; Wound Healing | 2016 |
Increased fibrosis and impaired intratumoral accumulation of macromolecules in a murine model of pancreatic cancer co-administered with FGF-2.
Topics: Albumin-Bound Paclitaxel; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Collagen Type I; Dextrans; Disease Models, Animal; Fibroblast Growth Factor 2; Fibrosis; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Hydroxyproline; Male; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; RNA, Messenger; Xenograft Model Antitumor Assays | 2016 |
Anti-osteoarthritic activity of Bungarus fasciatus venom fraction BF-F47 involving molecular markers in the rats.
Topics: Animals; Biological Products; Biomarkers; Bone Density Conservation Agents; Bungarus; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dinoprostone; Disease Models, Animal; Elapid Venoms; Glucosamine; Hydroxyproline; India; Inflammation Mediators; Injections, Intraperitoneal; Joints; Male; Osteoarthritis; Osteocalcin; Protein Stability; Rats, Wistar; Reptilian Proteins | 2016 |
Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung.
Topics: Actins; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Connective Tissue Growth Factor; Cytoprotection; Disease Models, Animal; Disease Progression; Dronabinol; Drug Administration Schedule; Hydroxyproline; Lung; Male; Mice, Inbred DBA; Phosphorylation; PPAR gamma; Pulmonary Fibrosis; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Transforming Growth Factor beta1 | 2016 |
Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9.
Topics: Amides; Animals; Antioxidants; Biomarkers; Bleomycin; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Glycation End Products, Advanced; Hydroxyproline; Lipid Peroxidation; Lung; Male; Matrix Metalloproteinase 9; Oxidative Stress; Pulmonary Fibrosis; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2016 |
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.
Topics: Actins; Animals; Collagen; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Gene Expression Regulation; Humans; Hydroxyproline; Kidney Diseases; Male; Mice; Stereoisomerism | 2016 |
HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.
Topics: Animals; Bile Ducts; Disease Models, Animal; Humans; Hydroxyproline; Hypoxia-Inducible Factor 1, alpha Subunit; Integrin beta1; Ligation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2017 |
Effect of Topical Platelet-Rich Plasma on Burn Healing After Partial-Thickness Burn Injury.
Topics: Animals; Burns; Disease Models, Animal; Hydroxyproline; Male; Platelet-Rich Plasma; Random Allocation; Rats; Rats, Wistar; Wound Healing | 2016 |
Traditional Chinese Medicine Formula "Xiaofeng granules" suppressed gouty arthritis animal models and inhibited the proteoglycan degradation on chondrocytes induced by monosodium urate.
Topics: ADAMTS4 Protein; Animals; Arthritis, Gouty; Cells, Cultured; Chondrocytes; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glycosaminoglycans; Gout Suppressants; Hydroxyproline; Inflammation Mediators; Joints; Male; Matrix Metalloproteinase 3; Proteoglycans; Proteolysis; Rabbits; Rats, Sprague-Dawley; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-3; Uric Acid | 2016 |
Metabolomics study of renal fibrosis and intervention effects of total aglycone extracts of Scutellaria baicalensis in unilateral ureteral obstruction rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Discriminant Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Gas Chromatography-Mass Spectrometry; Hydroxyproline; Kidney; Kidney Diseases; Losartan; Male; Metabolomics; Multivariate Analysis; Phytotherapy; Plant Extracts; Plants, Medicinal; Principal Component Analysis; Rats, Wistar; Scutellaria baicalensis; Time Factors; Ureteral Obstruction; Urological Agents | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2016 |
Evaluation of potent phytomedicine for treatment of psoriasis using UV radiation induced psoriasis in rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Dermatologic Agents; Disease Models, Animal; Ethanol; Female; Gardenia; Gels; Hydroxyproline; Male; Pharmaceutical Solutions; Phytotherapy; Plant Extracts; Plants, Medicinal; Psoriasis; Rats, Wistar; Severity of Illness Index; Skin; Solvents; Ultraviolet Rays; Woodfordia | 2016 |
Automated evaluation of liver fibrosis in thioacetamide, carbon tetrachloride, and bile duct ligation rodent models using second-harmonic generation/two-photon excited fluorescence microscopy.
Topics: Animals; Automation, Laboratory; Bile Ducts; Carbon Tetrachloride; Disease Models, Animal; Hydroxyproline; Ligation; Liver; Liver Cirrhosis; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Rats, Sprague-Dawley; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Thioacetamide | 2017 |
Antifibrotic Effects of Carvedilol and Impact of Liver Fibrosis on Carvedilol Pharmacokinetics in a Rat model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers; Carbazoles; Carvedilol; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis; Male; Propanolamines; Rats; Rats, Wistar; Transforming Growth Factor beta1 | 2017 |
Optimized Mouse Models for Liver Fibrosis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Azo Compounds; Biomarkers; Carbon Tetrachloride; Collagen; Disease Models, Animal; Disease Progression; Extracellular Matrix; Gene Expression; Histocytochemistry; Humans; Hydroxyproline; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Thioacetamide | 2017 |
Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Chitosan; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydroxyproline; Ink; Malondialdehyde; Molecular Weight; Random Allocation; Rats; Sepia; Stomach Ulcer | 2016 |
Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Disease Progression; Hydroxyproline; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Pulmonary Fibrosis; Transforming Growth Factor alpha | 2017 |
Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation.
Topics: Actins; Animals; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Chemokine CCL2; Collagen; Diet, High-Fat; Disease Models, Animal; Fibrosis; Heart Atria; Heart Rate; Hydroxyproline; Isolated Heart Preparation; Leptin; Male; Mice, Inbred C57BL; Mice, Obese; Obesity; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Effect of thalidomide on the healing of colonic anastomosis, in rats.
Topics: Anastomosis, Surgical; Angiogenesis Inhibitors; Animals; Biomarkers; Collagen; Colon; Disease Models, Animal; Hydroxyproline; Male; Matrix Metalloproteinase 1; Random Allocation; Rats; Rats, Wistar; Surgical Wound Dehiscence; Thalidomide; Vascular Endothelial Growth Factor A; Wound Healing | 2008 |
Effects of preoperative pelvic irradiation on colonic anastomosis healing. An experimental study in rats.
Topics: Anastomosis, Surgical; Animals; Collagen; Colon; Disease Models, Animal; Hydroxyproline; Male; Matrix Metalloproteinase 1; Pelvis; Preoperative Care; Radiotherapy Dosage; Rats; Rats, Wistar; Rectum; Surgical Wound Dehiscence; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A; Wound Healing | 2008 |
A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Lung; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Pulmonary Fibrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Seeds; Silicon Dioxide; Vitamin E; Vitis | 2008 |
A TSP-1 synthetic peptide inhibits bleomycin-induced lung fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Lung; Mice; Peptide Fragments; Pulmonary Fibrosis; Thrombospondin 1 | 2009 |
Attenuation effects of heparin-superoxide dismutase conjugate on bleomycin-induced lung fibrosis in vivo and radiation-induced inflammatory cytokine expression in vitro.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression; Heparin; Hydroxyproline; Inflammation; Interleukin-1beta; Lung; Male; Mice; Pulmonary Fibrosis; Superoxide Dismutase; Transforming Growth Factor beta1; X-Rays | 2009 |
The effects of intraperitoneal sildenafil administration on healing of left colonic anastomoses and intra-abdominal adhesion formation in the presence of intra-abdominal infection.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Injections, Intraperitoneal; Peritonitis; Phosphodiesterase Inhibitors; Pilot Projects; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tissue Adhesions; Wound Healing | 2008 |
Platelets contribute to the reduction of liver fibrosis in mice.
Topics: Animals; Blood Platelets; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation; Hydroxyproline; Liver; Liver Cirrhosis; Liver Regeneration; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitotic Index; Phosphorylation; Platelet Count; Proto-Oncogene Proteins c-akt; RNA, Messenger; Splenectomy; Thrombocytosis; Thrombopoietin; Transforming Growth Factor beta | 2009 |
Development of hepatorenal syndrome in bile duct ligated rats.
Topics: Animals; Bile Ducts; Creatinine; Disease Models, Animal; Disease Progression; Hepatorenal Syndrome; Hydroxyproline; Kidney; Ligation; Liver; Male; Rats; Rats, Wistar | 2008 |
The effects of adjuvant experimental radioimmunotherapy and hyperthermic intraperitoneal chemotherapy on intestinal and abdominal healing after cytoreductive surgery for peritoneal carcinomatosis in the rat.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Combined Modality Therapy; Disease Models, Animal; Gelatinases; Hydroxyproline; Hyperthermia, Induced; Injections, Intraperitoneal; Intestines; Lutetium; Male; Mitomycin; Peritoneal Neoplasms; Radioimmunotherapy; Rats; Rats, Inbred Strains; Survival Rate; Treatment Outcome; Wound Healing | 2008 |
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression; Hydroxyproline; Immunoglobulin E; Lung; Mice; Mice, Inbred C57BL; Ovalbumin; Pneumonia; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2009 |
Wound healing properties of Carica papaya latex: in vivo evaluation in mice burn model.
Topics: Animals; Burns; Carica; Chlorhexidine; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelium; Hydrogels; Hydroxyproline; Latex; Male; Medicine, Traditional; Mice; Plant Extracts; Silver Sulfadiazine; Wound Healing | 2009 |
Effects of the amniotic membrane on healing of colonic anastomoses in experimental left-sided colonic obstruction.
Topics: Amnion; Anastomosis, Surgical; Animals; Colonic Diseases; Disease Models, Animal; Female; Humans; Hydroxyproline; Intestinal Obstruction; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Wound Healing | 2010 |
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; Catechin; Cell Proliferation; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelins; Enzyme Inhibitors; Fibroblasts; Fibrosis; Hydroxyproline; Male; Myocardium; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transcription Factors | 2009 |
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Topics: Administration, Inhalation; Animals; Asthma; Base Sequence; Bronchoalveolar Lavage Fluid; Cells, Cultured; Collagen; Disease Models, Animal; DNA Primers; Female; Fibrinolysin; Fibrinolysis; Fibrosis; Hepatocyte Growth Factor; Humans; Hydroxyproline; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Proto-Oncogene Proteins c-met; Serpin E2; Serpins; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator | 2009 |
[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibrosis; Hydroxyproline; Male; Metoprolol; Myocardial Infarction; Myocardium; Propanolamines; Rats; Rats, Sprague-Dawley | 2008 |
Treatment of chronic proliferative cholangitis with c-myc shRNA.
Topics: Animals; Cholangitis; Collagen Type III; Disease Models, Animal; Gallstones; Genes, myc; Glucuronidase; Hydroxyproline; Mucin 5AC; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Recurrence; RNA, Small Interfering | 2009 |
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Models, Animal; Esophageal Stenosis; Esophagus; Hydroxyproline; Mitomycin; Rats; Rats, Wistar; Weight Gain; Weight Loss | 2009 |
Effects of amniotic membrane on the healing of primary colonic anastomoses in the cecal ligation and puncture model of secondary peritonitis in rats.
Topics: Amnion; Anastomosis, Surgical; Animals; Cecum; Colon; Disease Models, Animal; Female; Humans; Hydroxyproline; Ligation; Peritonitis; Pressure; Punctures; Rats; Rats, Sprague-Dawley; Wound Healing | 2009 |
[Function of type I repetitive consequence peptide segment of thrombospondin-1 in inhibition of fibrosis of mice].
Topics: Animals; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Lung; Mice; Thrombospondin 1 | 2009 |
K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function.
Topics: Animals; Aorta, Abdominal; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Agents; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Fibrosis; Heart Failure; Heart Rate; Hydroxyproline; Hypertension; Hypertrophy, Left Ventricular; KATP Channels; Male; Myocardium; Natriuretic Peptide, Brain; Nitric Oxide; Propylamines; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Ventricular Remodeling | 2009 |
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Bone Marrow Cells; Chondrocytes; Collagen Type I; Collagen Type IV; Disease Models, Animal; Female; Hematopoietic Stem Cells; Hydroxyproline; Immunohistochemistry; Mice; Mice, Inbred Strains; Pulmonary Fibrosis; Transforming Growth Factor beta1 | 2009 |
Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis; Mice; Muscle, Smooth; Relaxin; Swine | 2009 |
The effect of cyanoacrylate in esophagocutaneous leakages occurring after esophageal anastomosis.
Topics: Anastomosis, Surgical; Animals; Cutaneous Fistula; Cyanoacrylates; Disease Models, Animal; Esophageal Fistula; Esophagus; Humans; Hydroxyproline; Rabbits; Tissue Adhesives; Wound Healing | 2009 |
Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Dexamethasone; Disease Models, Animal; Hydroxyproline; Lipopolysaccharides; Pulmonary Fibrosis; Rats; Rats, Wistar; Smad Proteins; STAT Transcription Factors; Th1 Cells; Th2 Cells | 2009 |
Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.
Topics: Animals; Animals, Congenic; Calcium Oxalate; Chromosomes, Mammalian; Disease Models, Animal; Genetic Predisposition to Disease; Hydroxyproline; Hyperoxaluria; Kidney Calculi; Kidney Tubules; Male; Phenotype; Rats; Rats, Inbred BN; Rats, Inbred Dahl; Severity of Illness Index; Species Specificity; Time Factors; Urothelium | 2009 |
Estrogen deficiency and tobacco smoke exposure promote matrix metalloproteinase-13 activation in skin of aging B6 mice.
Topics: Animals; Disease Models, Animal; Enzyme Activation; Estradiol; Estrogens; Female; Hydroxyproline; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Ovariectomy; Random Allocation; Reference Values; Risk Factors; Sensitivity and Specificity; Skin Aging; Smoke | 2009 |
Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice.
Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Hydroxyproline; Mice; Pulmonary Fibrosis; Radiotherapy; Taurine; Thorax; Time Factors; Transforming Growth Factor beta1 | 2010 |
Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis.
Topics: Animals; Bleomycin; Body Weight; Cell Survival; Cells, Cultured; Citrus; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2009 |
Anti-fibrotic effects of a methylenedioxybenzene compound, CW209292 on dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Benzodioxoles; Body Weight; Cell Proliferation; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatic Stellate Cells; Hydroxyproline; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Molecular Structure; Prothrombin Time; Rats; Rats, Sprague-Dawley; Survival Analysis; Thiazoles | 2009 |
Simvastatin attenuates experimental small airway remodelling in rats.
Topics: Airway Remodeling; Animals; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Lung; Male; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Smad Proteins; Tobacco Smoke Pollution; Transforming Growth Factor beta1 | 2009 |
Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats.
Topics: Animals; Atorvastatin; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypertension; Hypertrophy, Left Ventricular; Lipids; Male; MEF2 Transcription Factors; Myocardium; Protein Kinase C; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Time Factors; Transcription Factors; Ventricular Remodeling | 2010 |
Melatonin prevents peritoneal adhesions in rats.
Topics: Administration, Oral; Animals; Antioxidants; Cecum; Disease Models, Animal; Hydroxyproline; Male; Malondialdehyde; Melatonin; Peritoneal Diseases; Pineal Gland; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Adhesions | 2009 |
Effect of Laggera alata on hepatocyte damage induced by carbon tetrachloride in vitro and in vivo.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Asteraceae; Blood Proteins; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Hepatocytes; Hydroxyproline; Male; Mice; Mice, Inbred ICR; N-Acetylneuraminic Acid; Phytotherapy; Plant Extracts; Quinic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin | 2009 |
Fluid regimen for intestinal anastomosis.
Topics: Anastomosis, Surgical; Animals; Crystalloid Solutions; Disease Models, Animal; Fluid Therapy; Hydroxyproline; Ileum; Isotonic Solutions; Male; Rats; Rats, Wistar; Rehydration Solutions; Water-Electrolyte Imbalance; Wound Healing | 2009 |
Rolipram attenuates bleomycin A5-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytokines; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Male; Malondialdehyde; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Rolipram; Tumor Necrosis Factor-alpha | 2009 |
Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Hydroxyproline; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis | 2009 |
Cardiac fibrosis and diastolic dysfunction after myocardial infarction in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; Body Weight; Diastole; Disease Models, Animal; Echocardiography, Doppler; Fibrosis; Genotype; Hydroxyproline; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Phenotype; Ventricular Dysfunction, Left; Ventricular Remodeling | 2009 |
Effect of antler extract on corticosteroid-induced avascular necrosis of the femoral head in rats.
Topics: Animals; Animals, Newborn; Antlers; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Deer; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femur Head; Femur Head Necrosis; Glucocorticoids; Hexosamines; Hydroxyproline; Male; Materia Medica; Medicine, Chinese Traditional; Osteoblasts; Random Allocation; Rats; Rats, Wistar; Tissue Extracts | 2010 |
Emodin protects rat liver from CCl(4)-induced fibrogenesis via inhibition of hepatic stellate cells activation.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Disease Models, Animal; Emodin; Fibrosis; Hepatic Stellate Cells; Hydroxyproline; Immunohistochemistry; Liver; Male; Olive Oil; Plant Oils; Rats; Rats, Sprague-Dawley | 2009 |
Extracorporeal photopheresis in a rat model of pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Hydroxyproline; Interferon-gamma; Interleukin-10; Lung; Photopheresis; Pulmonary Fibrosis; Rats; Rats, Inbred Lew; Severity of Illness Index; Time Factors; Transforming Growth Factor beta | 2009 |
Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line; Cell Proliferation; Collagen Type I; Dimethylnitrosamine; Disease Models, Animal; Hepatic Stellate Cells; Hydroxyproline; Lipid Peroxides; Liver Cirrhosis; Male; Plant Extracts; Rats; Rats, Inbred Strains; Tea; Treatment Outcome | 2009 |
Pulmonary fibrosis induced by H5N1 viral infection in mice.
Topics: Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Pulmonary Fibrosis; Respiratory Distress Syndrome | 2009 |
Prevention of osteoporosis in mice after ovariectomy via allograft of microencapsulated ovarian cells.
Topics: Alginates; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Bone and Bones; Bone Remodeling; Cells, Cultured; Chondrocytes; Disease Models, Animal; Estradiol; Female; Femur; Hydroxyproline; Immunohistochemistry; Lumbar Vertebrae; Matrix Metalloproteinase 9; Mice; Osteoblasts; Osteoclasts; Osteoporosis; Ovariectomy; Ovary; Polylysine; Staining and Labeling; Tibia; Time Factors; Transplantation, Homologous | 2010 |
[The effect of urokinase on hepatic fibrogenesis in rats].
Topics: Actins; Animals; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Plasminogen Activator Inhibitor 1; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator | 2009 |
Effect of isoflavone-enriched milk on bone mass in ovariectomized rats.
Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Disease Models, Animal; Female; Hydroxyproline; Isoflavones; Osteoporosis; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Soy Milk | 2009 |
A CD36 synthetic peptide inhibits silica-induced lung fibrosis in the mice.
Topics: Animals; CD36 Antigens; Collagen Type I; Collagen Type III; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Inhalation Exposure; Lung; Mice; Mice, Inbred ICR; Peptide Fragments; Peptides; Silicosis | 2010 |
Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model.
Topics: Acids; Animals; Diet; Disease Models, Animal; Female; Glycolates; Hydrogen-Ion Concentration; Hydroxyproline; Hyperoxaluria; Oxalates; Sus scrofa | 2010 |
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Female; gamma-Aminobutyric Acid; Hydroxyproline; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Receptors, CCR3; Transforming Growth Factor beta1; Urea | 2010 |
Evaluation of a new type of wound dressing made from recombinant spider silk protein using rat models.
Topics: Animals; Biological Dressings; Burns; Collagen; Disease Models, Animal; Fibroblast Growth Factor 2; Hydroxyproline; Immunohistochemistry; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Silk; Skin; Spiders; Wound Healing | 2010 |
[Therapeutic effect of Haobieyangyinruanjianfang on the mouse liver fibrosis caused by schistosomiasis].
Topics: Animals; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Materia Medica; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Schistosoma japonicum; Schistosomiasis japonica; Severity of Illness Index; Sex Factors; Treatment Outcome | 2010 |
The changes in various hydroxyproline fractions in aortic tissue of rabbits are closely related to the progression of atherosclerosis.
Topics: Animals; Aorta; Atherosclerosis; Cholesterol; Cholesterol, LDL; Collagen; Dietary Fats; Disease Models, Animal; Disease Progression; Hydroxyproline; Male; Olive Oil; Plant Oils; Rabbits; Thoracic Arteries; Triglycerides | 2010 |
A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Iloprost; Inflammation Mediators; Injections, Intraperitoneal; Lung; Lung Compliance; Male; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Weight Loss | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation End Products, Advanced; Hydroxyproline; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Silicosis; Transforming Growth Factor beta | 2010 |
Effects of Haobie Yangyin Ruanjian decoction on hepatic fibrosis induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Blotting, Western; Carbon Tetrachloride; Collagen Type III; Collagen Type IV; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyaluronic Acid; Hydroxyproline; Laminin; Liver; Liver Cirrhosis; Male; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2010 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, Animal; Gene Expression; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Macrophages; Male; Malondialdehyde; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Size; Phytotherapy; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Seeds | 2010 |
Effectiveness of topical zinc oxide application on hypertrophic scar development in rabbits.
Topics: Administration, Topical; Animals; Cicatrix, Hypertrophic; Dermatologic Agents; Disease Models, Animal; Ear, External; Hydroxyproline; Rabbits; Wound Healing; Wounds and Injuries; Zinc; Zinc Oxide | 2010 |
Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Chronic Disease; Collagen; Daunorubicin; Disease Models, Animal; Drug Interactions; Fibrosis; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Rabbits; Razoxane; Ventricular Remodeling | 2010 |
N-acetyl cysteine promotes angiogenesis and clearance of free oxygen radicals, thus improving wound healing in an alloxan-induced diabetic mouse model of incisional wound.
Topics: Acetylcysteine; Alloxan; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Free Radical Scavengers; Glutathione; Hydroxyproline; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Skin; Vascular Endothelial Growth Factors; Wound Healing; Wounds, Penetrating | 2010 |
Functional and structural changes in end-stage kidney disease due to glomerulonephritis induced by the recombinant alpha3(IV)NC1 domain.
Topics: Actins; Animals; Autoantigens; Collagen Type I; Collagen Type IV; Creatinine; Disease Models, Animal; Female; Gene Expression; Glomerulonephritis; Hydroxyproline; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Function Tests; Lisinopril; Mycophenolic Acid; Prednisolone; Rats; Rats, Inbred WKY; Recombinant Proteins; Transforming Growth Factor beta1 | 2010 |
Mizoribine protects against bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Proliferation; Disease Models, Animal; Female; Hydroxyproline; Immunosuppressive Agents; Lung; Lung Diseases, Interstitial; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Ribonucleosides; Time Factors | 2010 |
Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Disease Progression; Female; Hydroxyproline; Immunohistochemistry; Leukotriene B4; Leukotrienes; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Leukotriene; Receptors, Leukotriene B4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Silicon Dioxide; Time Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2010 |
Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and Schistosomal infection in mice.
Topics: Animals; Bilirubin; Biomarkers; Biopsy; Collagen; Disease Models, Animal; Ethanol; gamma-Glutamyltransferase; Glutathione; Hydroxyproline; Liver; Liver Cirrhosis; Mice; Mice, Inbred Strains; Schistosoma mansoni; Schistosomiasis mansoni; Severity of Illness Index; Thioacetamide | 2010 |
Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylene Glycol; Hydroxyproline; Kidney; Kidney Calculi; Male; Mucoproteins; Osteopontin; Rats; Rats, Inbred F344; Rats, Wistar; Risk Factors; Species Specificity; Uromodulin | 2010 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fibroblasts; Hydroxyproline; Male; Mitomycin; Postoperative Complications; Rabbits; Tissue Adhesions; Treatment Outcome | 2010 |
Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Connective Tissue Growth Factor; Cyclin D1; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Hydroxyproline; Mice; Mice, Inbred C57BL; Pravastatin; Pulmonary Fibrosis; Respiratory Distress Syndrome; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Transforming Growth Factor beta1 | 2010 |
A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzamides; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Dioxoles; Disease Models, Animal; Fibrosis; Genes, Reporter; Hydroxyproline; Imidazoles; Kidney; Luciferases; Male; Protein Serine-Threonine Kinases; Rats; Rats, Transgenic; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Sensitivity and Specificity; Tetrazoles; Ureteral Obstruction | 2010 |
Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride- and ethanol-induced hepatic damage.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Liver; Lutein; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Experimental induction of calcium oxalate nephrolithiasis in mice.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Glyoxylates; Hydroxyproline; Male; Mice; Nephrolithiasis | 2010 |
The effect of sealing with a fixed combination of collagen matrix-bound coagulation factors on the healing of colonic anastomoses in experimental high-risk mice models.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Collagen; Collagen Type I; Collagen Type III; Colon; Disease Models, Animal; Drug Combinations; Fibrin Tissue Adhesive; Fibrinogen; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Peritonitis; Risk Factors; Thrombin; Wound Healing | 2010 |
Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury.
Topics: Amides; Animals; Caustics; Collagen; Disease Models, Animal; Enzyme Inhibitors; Esophageal Stenosis; Esophagus; Hydroxyproline; Male; Malondialdehyde; Pantothenic Acid; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Hydroxide; Vitamin B Complex | 2011 |
Mandibular bone density and calcium content affected by different kind of stress in mice.
Topics: Adrenal Glands; Animals; Bone Density; Calcium; Disease Models, Animal; Electroshock; Hydrocortisone; Hydroxyproline; Male; Mandible; Mice; Organ Size; Osteoporosis; Stress, Psychological | 2010 |
The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension.
Topics: Animals; Biomechanical Phenomena; Blood Pressure; Chronic Disease; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Elastic Modulus; Elastin; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Mechanotransduction, Cellular; Mice; Mice, Transgenic; Mutation; Pulmonary Artery; Recovery of Function; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Collagen Type I; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Hydroxyproline; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Liver; Liver Cirrhosis; Mice; Mice, Inbred BALB C; Monoterpenes; Paeonia; Plant Roots; Random Allocation; Schistosomiasis japonica | 2009 |
Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.
Topics: Animals; Apoptosis; Blood Cell Count; Bone Marrow; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Hydroxyproline; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Methotrexate; Mice; Mice, Inbred C57BL; Pulmonary Alveoli; Pulmonary Fibrosis | 2010 |
A natural process of cirrhosis resolution and deceleration of liver regeneration after thioacetamide withdrawal in a rat model.
Topics: Animals; Body Weight; Collagen; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Interleukin-6; Liver; Liver Cirrhosis; Liver Function Tests; Liver Regeneration; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Staining and Labeling; Thioacetamide; Transforming Growth Factor beta1 | 2011 |
Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis.
Topics: Animals; Benzofurans; Caffeic Acids; Collagen Type III; Connective Tissue Growth Factor; Disease Models, Animal; Glutathione Peroxidase; Hyaluronic Acid; Hydroxyproline; Immunohistochemistry; Laminin; Liver; Liver Cirrhosis; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta1 | 2011 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, Animal; Goblet Cells; Hydroxyproline; Hyperplasia; Immunohistochemistry; Inflammation; Lung; Mice; Nitrates; Nitrites; Ovalbumin; Simvastatin; Transforming Growth Factor beta1 | 2010 |
Improved methodology to induce hyperoxaluria without treatment using hydroxyproline.
Topics: Animals; Crystallization; Disease Models, Animal; Hydroxyproline; Hyperoxaluria; Kidney; Male; Oxalic Acid; Rats; Rats, Inbred BN; Rats, Inbred Dahl | 2011 |
Plantarflexion contracture in the mdx mouse.
Topics: Animals; Collagen; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Range of Motion, Articular; Torque | 2010 |
Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect.
Topics: Animals; Diastole; Disease Models, Animal; Female; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypercholesterolemia; Lipids; Microcirculation; Microvessels; Myocardium; Simvastatin; Swine; Tomography, X-Ray Computed; X-Ray Microtomography | 2011 |
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Biomechanical Phenomena; Body Weight; Disease Models, Animal; Elasticity; Fibrosis; Hydroxyproline; Male; Mice; Mice, Inbred mdx; Microscopy, Electron, Transmission; Muscle Strength; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Stress, Mechanical; Tendons; Viscosity | 2011 |
Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis.
Topics: Aging; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Drosophila melanogaster; Ethylene Glycol; Female; Hydroxyproline; Longevity; Male; Malpighian Tubules; Microscopy, Electron, Scanning; Microscopy, Polarization; Nephrolithiasis; Oxalates; Potassium Citrate; Spectrometry, X-Ray Emission; Triazines; Urolithiasis | 2011 |
Wound healing and antimicrobial potential of Carissa spinarum Linn. in albino mice.
Topics: Animals; Anti-Infective Agents; Apocynaceae; Burns; Collagen; Disease Models, Animal; Epithelium; Female; Granulation Tissue; Hydroxyproline; Male; Mice; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Skin; Wound Healing | 2011 |
A novel method for accurate collagen and biochemical assessment of pulmonary tissue utilizing one animal.
Topics: Analysis of Variance; Animals; Asbestos, Crocidolite; Asbestosis; Azo Compounds; Biomarkers; Collagen; Colorimetry; Coloring Agents; Disease Models, Animal; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Reproducibility of Results; Severity of Illness Index; Spectrophotometry; Up-Regulation | 2011 |
Effects and mechanisms of Acremoniumterricola milleretal mycelium on liver fibrosis induced by carbon tetrachloride in rats.
Topics: Acremonium; Animals; Antioxidants; Biological Products; Carbon Tetrachloride; Disease Models, Animal; Drugs, Chinese Herbal; Glutathione Peroxidase; Hyaluronic Acid; Hydroxyproline; Laminin; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Mycelium; Phosphorylation; Procollagen; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Superoxide Dismutase; Transaminases; Transforming Growth Factor beta1 | 2011 |
Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.
Topics: Animals; Biomarkers; Blotting, Western; Cell Proliferation; Disease Models, Animal; Ethanol; Fatty Liver, Alcoholic; Female; Gene Expression Regulation; Hepatic Stellate Cells; Hepatitis, Alcoholic; Hydroxyproline; Inflammation Mediators; Liver; Liver Cirrhosis, Alcoholic; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Triglycerides | 2011 |
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Humans; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutant Proteins; Plasminogen Activator Inhibitor 1; Protein Binding; Pulmonary Fibrosis; Recombinant Proteins; Serpin E2; Vitronectin | 2011 |
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Glutathione; Granuloma; Humans; Hydroxyproline; Liver Cirrhosis, Experimental; Liver Function Tests; Losartan; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred ICR; Parasite Egg Count; Praziquantel; Schistosomiasis mansoni; Transforming Growth Factor beta1 | 2011 |
The effect of alpha-lipoic acid in the prevention of peritoneal adhesions.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Male; Malondialdehyde; Oxidative Stress; Peritoneum; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tissue Adhesions | 2011 |
Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model.
Topics: Administration, Topical; Amines; Animals; Bacitracin; Benzopyrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Female; Granulation Tissue; Hydroxyproline; Male; Medicine, Ayurvedic; Neomycin; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Polymyxin B; Proteins; Rabbits; Rats; Rats, Wistar; Sitosterols; Skin; Wound Healing; Wounds and Injuries | 2011 |
Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Alkanes; Animals; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cissus; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Femur; Humans; Hydroxyproline; Isoenzymes; Osteoporosis, Postmenopausal; Ovariectomy; Phytotherapy; Plant Extracts; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase | 2011 |
Dietary induction of long-term hyperoxaluria in the porcine model.
Topics: Animals; Catheterization; Diet; Disease Models, Animal; Gelatin; Hydroxyproline; Hyperoxaluria; Oxalates; Sus scrofa; Time Factors | 2012 |
Comparison of antioxidative and antifibrotic effects of α-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis.
Topics: Actins; Administration, Oral; alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hydroxyproline; Male; Malondialdehyde; Organotin Compounds; Oxidative Stress; Pancreas; Pancreatitis, Chronic; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tocotrienols; Transforming Growth Factor beta1 | 2011 |
Assessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Body Temperature; Body Weight; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Organ Size; Plethysmography, Whole Body; Pulmonary Fibrosis; Respiratory Mechanics | 2012 |
Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis.
Topics: Animals; Annexin A1; Biomimetic Materials; Bleomycin; Cytokines; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation; Hydroxyproline; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice; Mice, Knockout; Peptide Fragments; Pneumonia; Pulmonary Fibrosis; Time Factors | 2011 |
Hepatoprotective activity of a phytotherapeutic formula on thioacetamide--induced liver fibrosis model.
Topics: Animals; Disease Models, Animal; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Thioacetamide; Thiobarbituric Acid Reactive Substances | 2011 |
Healing promoting potentials of roots of Ficus benghalensis L. in albino rats.
Topics: Animals; Disease Models, Animal; Female; Ficus; Granulation Tissue; Hydroxyproline; Male; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Wound Healing; Wounds and Injuries | 2011 |
Puerarin prevents isoprenaline-induced myocardial fibrosis in mice by reduction of myocardial TGF-β1 expression.
Topics: Animals; Biological Products; Cardiomyopathies; Cardiotonic Agents; Collagen; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hydroxyproline; Isoflavones; Isoproterenol; Male; Mice; Mice, Inbred Strains; Myocardium; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Random Allocation; RNA, Messenger; Transforming Growth Factor beta1; Up-Regulation | 2012 |
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Disease Models, Animal; Disease Progression; Hepatic Stellate Cells; Humans; Hydroxyproline; In Vitro Techniques; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Receptor, PAR-2; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2012 |
Effects of acute inflammation induced in the rat paw on the deep digital flexor tendon.
Topics: Acute Disease; Animals; Carrageenan; Disease Models, Animal; Edema; Electrophoresis, Agar Gel; Extracellular Matrix Proteins; Hydroxyproline; Inflammation; Injections, Subcutaneous; Male; Matrix Metalloproteinase 2; Rats; Rats, Wistar; Tendinopathy; Tendon Injuries; Tendons | 2012 |
Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study.
Topics: Acetic Acid; Animals; Anti-Infective Agents; Capillary Permeability; Disease Models, Animal; Hydroxyproline; Inflammation; Male; Mice; Plant Extracts; Plants, Medicinal; Ranunculus; Rats; Rats, Sprague-Dawley; Skin; Wound Healing | 2012 |
Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Animal; Enzyme Inhibitors; Hyaluronoglucosaminidase; Hydroxyproline; Inflammation; Male; Mice; Oils, Volatile; Pinus; Plant Components, Aerial; Plant Oils; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Skin; Wound Healing | 2012 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; Knee Joint; Male; Mitomycin; Rabbits; Tissue Adhesions | 2012 |
Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Humanized; Bleomycin; Cytokines; Daclizumab; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Immunoglobulin G; Immunohistochemistry; Immunosuppressive Agents; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Scleroderma, Localized; Skin | 2012 |
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Body Weight; Collagen; Disease Models, Animal; Hydroxyproline; Hypertension; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Olmesartan Medoxomil; Pulsatile Flow; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Tetrazoles; Thiophenes; Vascular Stiffness | 2012 |
Exercise training post-MI favorably modifies heart extracellular matrix in the rat.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Electrocardiography; Extracellular Matrix; Heart Septum; Heart Ventricles; Hydroxyproline; Myocardial Infarction; Physical Conditioning, Animal; Rats | 2012 |
The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; CD4-Positive T-Lymphocytes; Cell Count; Disease Models, Animal; Drug Therapy, Combination; Gene Expression; Hydroxyproline; Interleukins; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta; Tretinoin | 2012 |
[Protective effects of Leonurus japonicas on myocardial remodeling induced by isoproterenol in rats].
Topics: Animals; Antioxidants; Collagen; Disease Models, Animal; Hemodynamics; Hydroxyproline; Immunohistochemistry; Isoproterenol; Leonurus; Male; Myocardium; Organ Size; Plant Extracts; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2011 |
Antifibrotic effects of Artemisia capillaris and Artemisia iwayomogi in a carbon tetrachloride-induced chronic hepatic fibrosis animal model.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Artemisia; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Collagen; Cytokines; Disease Models, Animal; Down-Regulation; Fatty Liver; Glutathione; Hydroxyproline; Inflammation; Korea; Liver; Liver Cirrhosis; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transaminases | 2012 |
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cell Proliferation; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Hydrochloric Acid; Hydroxyproline; Inflammation; Linear Models; Macrophages; Mice; Neutrophil Infiltration; Positron-Emission Tomography; Radiopharmaceuticals; Time Factors; X-Ray Microtomography | 2012 |
Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice.
Topics: Amylases; Animals; Ceruletide; Collagen; Disease Models, Animal; Fibrosis; Humans; Hydroxyproline; Injections, Intraperitoneal; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lipase; Male; Mice; Mice, Inbred C57BL; Pancreatitis, Chronic | 2012 |
Ethyl pyruvate improves healing of colonic anastomosis in a rat model of peritonitis.
Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Male; Peritonitis; Pressure; Pyruvates; Rats; Rats, Wistar; Sepsis; Wound Healing | 2012 |
A high molecular weight protein extract of Mastobranchus indicus (Mi-64) having antiarthritic activity in experimental animals.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Ankle Joint; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemokine CXCL1; Disease Models, Animal; Glucosamine; Hydroxyproline; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Polychaeta; Proteins; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2012 |
Effects of low-level laser therapy (GaAs) in an animal model of muscular damage induced by trauma.
Topics: Animals; Antioxidants; Cell Respiration; Collagen; Creatine Kinase; Disease Models, Animal; Hydroxyproline; Low-Level Light Therapy; Male; Mitochondria; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Wistar; Soft Tissue Injuries; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2013 |
A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.
Topics: Analysis of Variance; Animals; Apoptosis; Carrier Proteins; Cell Differentiation; Cells, Cultured; Creatinine; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Profiling; Glutathione; Glutathione Disulfide; HIV; HIV Infections; Humans; Hydroxyproline; Kidney Diseases; Mice; Mice, Transgenic; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Protein Serine-Threonine Kinases; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Time Factors; Transfection; Transforming Growth Factor beta1; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Up-Regulation; Wnt Signaling Pathway | 2012 |
UVA irradiation following treatment with topical 8-methoxypsoralen improves bleomycin-induced scleroderma in a mouse model, by reducing the collagen content and collagen gene expression levels in the skin.
Topics: Administration, Cutaneous; Animals; Bleomycin; Collagen Type I; Collagen Type III; Disease Models, Animal; Down-Regulation; Female; Hydroxyproline; Methoxsalen; Mice; Mice, Inbred C3H; Photosensitizing Agents; PUVA Therapy; Scleroderma, Systemic; Skin; Transforming Growth Factor beta1 | 2012 |
Metabolic regulatory and anti-oxidative effects of modified Bushen Huoxue decoction on experimental rabbit model of osteoarthritis.
Topics: Animals; Antioxidants; Cartilage, Articular; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Male; Malondialdehyde; Nitric Oxide; Osteoarthritis; Rabbits; Superoxide Dismutase; Synovial Membrane | 2013 |
A rat model of smoke inhalation injury.
Topics: Air Pollutants; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Capillary Permeability; Carboxyhemoglobin; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Interleukin-8; Lung; Male; Neutrophils; Organ Size; Rats; Rats, Sprague-Dawley; Smoke Inhalation Injury; Toxicity Tests; Wood | 2012 |
Molecular MR imaging of liver fibrosis: a feasibility study using rat and mouse models.
Topics: Animals; Carbon Tetrachloride; Collagen Type I; Contrast Media; Diethylnitrosamine; Disease Models, Animal; Gadolinium; Half-Life; Hydroxyproline; Liver; Liver Cirrhosis; Magnetic Resonance Imaging; Male; Mice; Molecular Imaging; Molecular Probes; Rats; Rats, Wistar | 2012 |
Sutureless primary repair of colonic perforation with a degradable stent in a porcine model of fecal peritonitis.
Topics: Albumins; Animals; Biocompatible Materials; Collagen; Colon; Disease Models, Animal; Feces; Female; Hydroxyproline; Intestinal Perforation; Leukocyte Count; Male; Operative Time; Peritonitis; Pressure; Reproducibility of Results; Stents; Survival Analysis; Sus scrofa; Sutures; Tissue Adhesions; Wound Healing | 2012 |
Protective effect of recombinant protein SOD-TAT on radiation-induced lung injury in mice.
Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Humans; Hydroxyproline; Lung Injury; Mice; Mice, Inbred C57BL; Pichia; Protein Structure, Tertiary; Radiation Injuries; Recombinant Fusion Proteins; Recombinant Proteins; Superoxide Dismutase; tat Gene Products, Human Immunodeficiency Virus | 2012 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genistein; Glutathione; Guanidines; Hydroxyproline; Isoproterenol; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiovascular Agents; Collagen Type I; Collagen Type III; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Diseases; Hydroxyproline; Hypertension; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Ghrelin; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Ventricular Dysfunction, Left; Ventricular Function, Left | 2012 |
The therapeutic efficacy of Ulinastatin for rats with smoking inhalation injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Cytokines; Disease Models, Animal; Fibrosis; Glycoproteins; Hydroxyproline; Male; Pneumonia; Rats; Rats, Sprague-Dawley; Smoke Inhalation Injury | 2012 |
Pomalidomide is effective for prevention and treatment of experimental skin fibrosis.
Topics: Animals; Disease Models, Animal; Fibrosis; Hydroxyproline; Immunosuppressive Agents; Mice; Mice, Inbred DBA; Mice, Mutant Strains; Myofibroblasts; Skin; Skin Diseases; Thalidomide | 2012 |
Effects of caffeic acid phenethyl ester on anastomotic healing in secondary peritonitis.
Topics: Anastomosis, Surgical; Animals; Caffeic Acids; Colon; Disease Models, Animal; Glutathione; Hydroxyproline; Male; Malondialdehyde; Peritonitis; Peroxidase; Phenylethyl Alcohol; Pressure; Rats; Rats, Wistar; Stress, Mechanical; Superoxide Dismutase; Wound Healing | 2012 |
[Corbrin shugan capsule for treatment of alcoholic hepatic fibrosis in rats].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Laminin; Liver; Liver Cirrhosis, Alcoholic; Male; Procollagen; Rats; Tissue Inhibitor of Metalloproteinase-1 | 2012 |
Transgenic mouse model with deficient mitochondrial polymerase exhibits reduced state IV respiration and enhanced cardiac fibrosis.
Topics: Analysis of Variance; Animals; Crosses, Genetic; Disease Models, Animal; DNA Polymerase gamma; DNA Primers; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Echocardiography; Endomyocardial Fibrosis; Genotype; Histological Techniques; Hydroxyproline; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Diseases; Mutation, Missense; Myocardial Contraction; Oximetry; Respiratory Physiological Phenomena; Zidovudine | 2013 |
LLLT improves tendon healing through increase of MMP activity and collagen synthesis.
Topics: Achilles Tendon; Animals; Collagen; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Lasers, Semiconductor; Low-Level Light Therapy; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Rupture; Tendon Injuries; Wound Healing | 2013 |
Altered microRNAs expression profiling in experimental silicosis rats.
Topics: Animals; Ceruloplasmin; Disease Models, Animal; Hydroxyproline; Lung; Male; Microarray Analysis; MicroRNAs; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Silicosis; Transcriptome | 2012 |
Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice.
Topics: Age Factors; Animals; Biomechanical Phenomena; Body Weight; Disease Models, Animal; Dystrophin; Elasticity; Fibrosis; Hydroxyproline; Isometric Contraction; Kinetics; Male; Mice; Mice, Inbred mdx; Mice, Transgenic; Muscle Strength; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Viscosity | 2013 |
A marginal level of dystrophin partially ameliorates hindlimb muscle passive mechanical properties in dystrophin-null mice.
Topics: Age Factors; Animals; Disease Models, Animal; Dystrophin; Gene Expression Regulation; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscular Dystrophies; Muscular Dystrophy, Animal; Mutation; Stress, Mechanical | 2012 |
Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2.
Topics: Administration, Intravenous; Animals; Bleomycin; Body Weight; Dinoprostone; Disease Models, Animal; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Kidney; Liposomes; Liver; Lung; Mice; RNA, Messenger; Spleen; Time Factors; Tissue Distribution | 2013 |
Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzoates; Bridged-Ring Compounds; Chemical and Drug Induced Liver Injury; Collagen Type I; Desmin; Dimethylnitrosamine; Disease Models, Animal; Glucosides; Hydroxyproline; Kidney; Liver; Liver Cirrhosis; Lung; Macrophages; Male; Monoterpenes; Paeonia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Spleen; Tumor Necrosis Factor-alpha | 2012 |
Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Glucocorticoids; Histocytochemistry; Humans; Hydroxyproline; Methylprednisolone; Mice; Mice, Inbred CBA; Orthoreovirus, Mammalian; Pulmonary Fibrosis; Reoviridae Infections; Respiratory Distress Syndrome; RNA; Specific Pathogen-Free Organisms | 2002 |
Renal interstitial fibrosis (RIF): II. Ultrasound follow up study of single uranyl nitrate administration causing renal dysfunction in rats--comparison with histologic and functional renal parameters.
Topics: Acute Disease; Animals; Creatinine; Disease Models, Animal; Female; Fibrosis; Follow-Up Studies; Gluconeogenesis; Hydroxyproline; In Vitro Techniques; Injections, Intraperitoneal; Kidney; Kidney Cortex; Nephritis, Interstitial; p-Aminohippuric Acid; Rats; Rats, Wistar; Ultrasonography, Doppler, Duplex; Uranyl Nitrate | 2002 |
Sustained release of cis-hydroxyproline in the treatment of experimental proliferative vitreoretinopathy in rabbits.
Topics: Absorbable Implants; Animals; Biocompatible Materials; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Fibroblasts; Hydroxyproline; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Sclera; Vitreoretinopathy, Proliferative | 2002 |
Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Guanidines; Hydroxyproline; Lipid Peroxidation; Lung; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Procollagen-Proline Dioxygenase; Pulmonary Fibrosis; Time Factors; Weight Gain | 2002 |
Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL8; Chemokine CXCL2; Desmosine; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Guinea Pigs; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Monocyte Chemoattractant Proteins; Monokines; Neutrophils; Pulmonary Emphysema; Serpins; Time Factors; Tobacco Smoke Pollution; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2002 |
Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure.
Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Collagen; Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; gamma-Cyclodextrins; Heart Failure; Hemodynamics; Hydroxyproline; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2002 |
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats.
Topics: Animals; Arterioles; Collagen; Coronary Vessels; Diastole; Disease Models, Animal; Food, Formulated; Heart; Hydroxyproline; Hyperhomocysteinemia; Hypertension; Immunohistochemistry; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardium; Rats; Rats, Inbred SHR; Ventricular Function, Left; Ventricular Remodeling | 2002 |
An investigation on skin wound healing in mice with a taurine-chitosan gel formulation.
Topics: Animals; Antioxidants; Biocompatible Materials; Chemistry, Pharmaceutical; Chitin; Chitosan; Collagen; Disease Models, Animal; Drug Delivery Systems; Hydroxyproline; Materials Testing; Mice; Microscopy, Electron; Skin Diseases; Taurine; Tensile Strength; Wound Healing | 2002 |
[The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis].
Topics: Animals; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Collagen; Disease Models, Animal; Hydroxyproline; Lung; Macrophage Inflammatory Proteins; Male; Methylprednisolone; Panax; Phytotherapy; Pulmonary Fibrosis; Rats; Rats, Wistar | 2002 |
Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Models, Animal; Erythromycin; Hydroxyproline; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lung; Lung Diseases, Interstitial; Macrophages; Male; Mice; Mice, Inbred ICR; Neutrophils; P-Selectin; RNA, Messenger; Vascular Cell Adhesion Molecule-1 | 2002 |
Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Body Weight; Ceruloplasmin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydroxyproline; Lung; Mice; Mice, Inbred CBA; Molybdenum; Pulmonary Fibrosis | 2003 |
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats.
Topics: Acetonitriles; Acetylcysteine; Animals; Antioxidants; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Lung; Macrophages, Alveolar; Male; NF-kappa B; Organ Size; Oxidative Stress; Pneumonia; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Trityl Compounds | 2003 |
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Cytokines; Disease Models, Animal; Gelatinases; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Ovalbumin; Pulmonary Fibrosis; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2003 |
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cricetinae; Disease Models, Animal; Hydroxyproline; Male; Membrane Potentials; Mitochondria; Oxygen Consumption; Pulmonary Fibrosis; Pyridones; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Effect of Holotrichia diomphalia larvae on liver fibrosis and hepatotoxicity in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Coleoptera; Disease Models, Animal; Drug Evaluation, Preclinical; Hydroxyproline; Larva; Liver; Liver Cirrhosis, Experimental; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tissue Extracts | 2003 |
An HSV-TK transgenic mouse model to evaluate elimination of fibroblasts for fibrosis therapy.
Topics: Animals; Antiviral Agents; Apoptosis; Cells, Cultured; Collagen Type I; Disease Models, Animal; Fibroblasts; Fibrosis; Ganciclovir; Genes, Reporter; Herpesvirus 1, Human; Humans; Hydroxyproline; Mice; Mice, Transgenic; Prostheses and Implants; Recombinant Fusion Proteins; Thymidine Kinase | 2003 |
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Female; Hydroxyproline; Injections, Intraperitoneal; Kidney Failure, Chronic; Losartan; Nephrectomy; p-Aminohippuric Acid; Proteinuria; Rats; Rats, Wistar; Tetrahydroisoquinolines; Uranyl Nitrate | 2003 |
Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis.
Topics: Animals; Apoptosis; Base Sequence; Biomarkers; Blotting, Northern; Collagenases; Disease Models, Animal; DNA Primers; Female; Gene Expression Regulation; Hydroxyproline; Male; Polymerase Chain Reaction; Pulmonary Fibrosis; Rats; Rats, Wistar; Respiratory Mucosa; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2003 |
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine.
Topics: Administration, Oral; Alanine Transaminase; Alcohol Deterrents; Animals; Bilirubin; Cholestasis, Extrahepatic; Colchicine; Collagen; Disease Models, Animal; Drug Combinations; gamma-Glutamyltransferase; Hydroxyproline; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Liver Glycogen; Male; Pyridoxine; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar | 2003 |
The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis.
Topics: Animals; Base Sequence; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; DNA Primers; Electrophoretic Mobility Shift Assay; Hydroxyproline; Mice; NF-kappa B; Niacin; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Taurine | 2003 |
Increase in tartrate-resistant acid phosphatase of bone at the early stage of ascorbic acid deficiency in the ascorbate-requiring Osteogenic Disorder Shionogi (ODS) rat.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Ascorbic Acid Deficiency; Body Weight; Bone Resorption; Calcium; Collagen Type I; Disease Models, Animal; Female; Femur; Hydroxyproline; Immunohistochemistry; Isoenzymes; Oligopeptides; Peptide Fragments; Peptides; Procollagen; Rats; Tartrate-Resistant Acid Phosphatase; Time Factors | 2003 |
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Extracellular Space; Hydroxyproline; Lung; Lung Diseases; Mice; Mice, Transgenic; Pulmonary Fibrosis; Pyrrolidinones; Superoxide Dismutase | 2003 |
Follow-up study of morphology and cardiac function in rats undergoing induction of supravalvular aortic stenosis.
Topics: Analysis of Variance; Animals; Aortic Stenosis, Supravalvular; Disease Models, Animal; Echocardiography; Hydroxyproline; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Wistar; Systole; Ventricular Function, Left | 2003 |
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Topics: Actins; Allergens; Animals; Antibodies; Asthma; Bronchi; Chemotaxis, Leukocyte; Collagen; Disease Models, Animal; Disease Progression; Eosinophils; Female; Fibroblasts; Hydroxyproline; Interleukin-5; Mice; Mice, Knockout; Ovalbumin; Pulmonary Fibrosis; Receptors, Interleukin; Receptors, Interleukin-5; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2004 |
A model of chronic heart failure in spontaneous hypertensive rats (SHR).
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Hydroxyproline; Hypertrophy, Left Ventricular; Lung; Magnetic Resonance Imaging; Male; Myocardial Contraction; Myocardial Infarction; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2004 |
A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis.
Topics: Animals; Antioxidants; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Immunohistochemistry; In Situ Hybridization; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Thioacetamide; Thiobarbituric Acid Reactive Substances; Thiocarbamates | 2004 |
Transforming growth factor beta1-induced glomerulopathy is prevented by 17beta-estradiol supplementation.
Topics: Animals; Basement Membrane; Disease Models, Animal; Estradiol; Extracellular Matrix; Female; Gene Expression; Glomerulonephritis; Hydroxyproline; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Promoter Regions, Genetic; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transgenes | 2004 |
Sequential changes in redox status and nitric oxide synthases expression in the liver after bile duct ligation.
Topics: Animals; Bile Ducts, Extrahepatic; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydroxyproline; Immunoenzyme Techniques; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Wistar | 2004 |
Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression.
Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Collagenases; Disease Models, Animal; DNA; Dose-Response Relationship, Radiation; Glycosaminoglycans; High-Energy Shock Waves; Hydroxyproline; Insulin-Like Growth Factor I; Rats; Rats, Sprague-Dawley; Tendinopathy; Tendon Injuries; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2004 |
A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling.
Topics: Animals; Burns, Chemical; Caustics; Collagen; Contrast Media; Disease Models, Animal; Esophageal Stenosis; Esophagus; Female; Hydroxyproline; Mucous Membrane; Muscle, Smooth; Phosphorylcholine; Radiography; Rats; Rats, Wistar; Second Messenger Systems; Sodium Hydroxide; Sphingosine; Treatment Outcome; Wound Healing | 2004 |
Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles.
Topics: Air Pollutants; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Hydroxyproline; Inflammation; Inhalation Exposure; Mice; Mice, Inbred BALB C; Ovalbumin; Particle Size; Specific Pathogen-Free Organisms | 2004 |
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibronectins; Fibrosis; Flow Cytometry; Gene Expression Regulation; Gene Targeting; Hydroxyproline; Immediate-Early Proteins; Immunohistochemistry; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Scleroderma, Systemic; Signal Transduction; Skin; Trans-Activators; Transforming Growth Factor beta | 2004 |
Animal models of scleroderma.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Disease Models, Animal; Flow Cytometry; Graft vs Host Disease; Humans; Hydroxyproline; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Scleroderma, Systemic; Skin | 2004 |
Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Bleomycin; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hydroxyproline; Immunohistochemistry; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Probability; Pulmonary Fibrosis; Pyridones; Random Allocation; Reference Values; Sensitivity and Specificity | 2004 |
[Effects of Fuzheng Huayu recipe on renal toxic interstitial fibrosis in rats].
Topics: Animals; Creatinine; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Fibrosis; Hydroxyproline; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Renal Insufficiency | 2004 |
The effects of castration and testosterone administration on mast cells and hydroxyproline in rat skin.
Topics: Animals; Castration; Cells, Cultured; Disease Models, Animal; Female; Hydroxyproline; Japan; Male; Mast Cells; Orchiectomy; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Skin; Testosterone | 1977 |
C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
Topics: Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Immunohistochemistry; Leukocyte Count; Lung; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred Strains; Proteins; Pulmonary Fibrosis; Receptors, CCR2; Receptors, Chemokine; Tumor Necrosis Factor-alpha | 2004 |
Antifibrotic effect of interferon gamma in silicosis model of rat.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Immunohistochemistry; Interferon-gamma; Interleukin-4; Lung; Male; Pulmonary Fibrosis; Quartz; Rats; Rats, Wistar; Silicosis; Transforming Growth Factor beta | 2005 |
Effect of Ganoderma tsugae on chronically carbon tetrachloride-intoxicated rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Disease Models, Animal; Ganoderma; Hydroxyproline; Liver; Liver Function Tests; Medicine, Chinese Traditional; Organ Size; Rats; Spleen | 2004 |
Mitomycin C prevents strictures in caustic esophageal burns in rats.
Topics: Alkalies; Animals; Antibiotics, Antineoplastic; Body Weight; Burns, Chemical; Disease Models, Animal; Esophageal Stenosis; Esophagus; Hydroxyproline; Mitomycin; Rats; Rats, Wistar | 2005 |
Combination of interferon-beta and angiotensin-converting enzyme inhibitor, perindopril, attenuates the murine liver fibrosis development.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Antiviral Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Cell Proliferation; Collagen Type I; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hydroxyproline; Interferon-beta; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Perindopril; Rats; Rats, Inbred F344; RNA, Messenger; Tetrazoles | 2005 |
Oxidative stress-mediated skin damage in an experimental mobile phone model can be prevented by melatonin.
Topics: Animals; Antioxidants; Catalase; Cell Phone; Disease Models, Animal; Fibrosis; Free Radical Scavengers; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Malondialdehyde; Melatonin; Oxidative Stress; Radiation Dosage; Radio Waves; Rats; Rats, Wistar; Skin; Superoxide Dismutase; Time Factors | 2004 |
No detrimental effects of repeated laparotomies on early healing of experimental intestinal anastomoses.
Topics: Anastomosis, Surgical; Animals; Biomarkers; Colon; Disease Models, Animal; Hydroxyproline; Ileum; Laparotomy; Male; Matrix Metalloproteinases; Peroxidase; Rats; Rats, Wistar; Reoperation; Wound Healing | 2005 |
Arterialisation of the portal vein as a model for the induction of hepatic fibrosis: description of microsurgical models in the rat.
Topics: Animals; Aorta; Azo Compounds; Coloring Agents; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Liver; Liver Circulation; Liver Cirrhosis; Liver Transplantation; Male; Microsurgery; Portal Vein; Procollagen; Rats; Rats, Inbred Lew; RNA, Messenger; Surgical Instruments; Ultrasonography; Vascular Surgical Procedures | 2005 |
Effect of relaxin on myocardial ischemia injury induced by isoproterenol.
Topics: Animals; Cardiomegaly; Creatine Kinase; Disease Models, Animal; Endothelins; Gene Expression; Heart; Hydroxyproline; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardium; Nerve Tissue Proteins; Organ Size; Rats; Rats, Sprague-Dawley; Relaxin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Ventricular Function, Left; Ventricular Pressure | 2005 |
Morphological signs of cirrhosis regression. Experimental observations on carbon tetrachloride-induced liver cirrhosis of rats.
Topics: Animals; Biomarkers; Biopsy; Carbon Tetrachloride; Disease Models, Animal; Female; Fluorescent Antibody Technique; Hepatocytes; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Recovery of Function; Remission, Spontaneous | 2005 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Lung; Male; Microscopy, Polarization; Paraquat; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Toxicity Tests; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2005 |
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
Topics: Animals; Bleomycin; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Epidermal Growth Factor; Fibroblasts; Growth Inhibitors; Hydroxyproline; Interferon-gamma; Lung; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Phosphorylation; Platelet-Derived Growth Factor; Pulmonary Fibrosis; STAT1 Transcription Factor; STAT3 Transcription Factor; Thymidine | 2005 |
Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma.
Topics: Adoptive Transfer; Animals; Bleomycin; Body Weight; Cells, Cultured; Disease Models, Animal; Hydroxyproline; Interferon-gamma; Killer Cells, Natural; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; T-Lymphocyte Subsets; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.
Topics: Animals; Apoptosis; Bleomycin; Cells; Collagen; Disease Models, Animal; Fibroblasts; Hydroxyproline; In Situ Nick-End Labeling; Leukocyte Count; Lung; Mice; Mice, Knockout; Neutrophils; Peroxidase; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein C; Weight Loss | 2005 |
Anti-monocyte chemoattractant protein 1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats.
Topics: Actins; Animals; Blotting, Western; Chemokine CCL2; Chemokines; Cytokines; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Therapy; Hydroxyproline; Injections, Intramuscular; Male; Organotin Compounds; Pancreas; Pancreatitis, Chronic; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2005 |
Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Lung; Male; Malondialdehyde; Melatonin; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Wistar | 2006 |
[The protective effect of recombinant Chinese interferon-gamma in pulmonary injury in mice].
Topics: Animals; Bleomycin; Collagen Type I; Collagen Type III; Disease Models, Animal; Humans; Hydroxyproline; Interferon-gamma; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Recombinant Proteins | 2005 |
Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma.
Topics: Animals; Bleomycin; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fibroblasts; Histamine Release; Hydroxyproline; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Intramolecular Oxidoreductases; Lipocalins; Mast Cells; Mice; Mice, Inbred C3H; Prostaglandin D2; RNA, Messenger; Scleroderma, Systemic; Sclerosis; Skin; Transfection | 2006 |
[Does sepsis impair the healing of colonic anastomosis in splenectomized rats?].
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Pressure; Rats; Rats, Wistar; Sepsis; Splenectomy; Tissue Adhesions; Wound Healing | 2005 |
Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol.
Topics: Acid Phosphatase; Alkaline Phosphatase; Allyl Compounds; Animals; Bone Density; Calcium; Cholesterol; Creatinine; Disease Models, Animal; Estradiol; Female; Humans; Hydroxyproline; Isoenzymes; Lovastatin; Osteoporosis, Postmenopausal; Ovariectomy; Phosphates; Rats; Recovery of Function; Sulfides; Tartrate-Resistant Acid Phosphatase | 2006 |
Combination of pre-operative radiotherapy and surgery suppresses local accumulation of collagen and TGF-beta1 in rats.
Topics: Animals; Collagen; Combined Modality Therapy; Disease Models, Animal; Hydroxyproline; Laparotomy; Male; Polytetrafluoroethylene; Postoperative Complications; Preoperative Care; Radiation Injuries, Experimental; Radiotherapy; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2006 |
Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Ginkgo biloba; Glutathione Peroxidase; Hydroxyproline; Lung; Male; Malondialdehyde; Nitrites; Plant Extracts; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2006 |
Colchicine in experimental alkaline burns of the rat esophagus: an old drug, a new indication?
Topics: Analysis of Variance; Animals; Burns, Chemical; Caustics; Colchicine; Disease Models, Animal; Dose-Response Relationship, Drug; Esophagus; Fibrosis; Hydroxyproline; Protective Agents; Rats; Rats, Wistar; Sodium Hydroxide; Treatment Outcome; Wound Healing | 2006 |
Citrus juice modulates bone strength in male senescent rat model of osteoporosis.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Antioxidants; Beverages; Bone and Bones; Bone Density; Citrus; Disease Models, Animal; Hydroxyproline; Male; Orchiectomy; Osteoporosis; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle.
Topics: Animals; Collagen Type I; Collagen Type III; Diaphragm; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Pentoxifylline; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Failure | 2006 |
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats.
Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hydroxyproline; Male; Myocardial Infarction; Rats; Rats, Wistar; Thalidomide; Ventricular Remodeling | 2006 |
Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Combined Modality Therapy; Disease Models, Animal; Female; Hydroxyproline; Hyperbaric Oxygenation; Immunohistochemistry; Inflammation Mediators; Intestinal Mucosa; Male; Mesalamine; Peroxidase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Treatment Outcome | 2006 |
Effect of peritoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis.
Topics: Anastomosis, Surgical; Animals; Anti-Infective Agents, Local; Colon; Disease Models, Animal; Female; Hydroxyproline; Peritoneal Lavage; Peritonitis; Pressure; Rats; Rats, Wistar; Taurine; Thiadiazines | 2006 |
[Immune complex induced rat liver fibrosis model by intraperitoneal injection of human serum albumin].
Topics: Animals; Antigen-Antibody Complex; Disease Models, Animal; Fibrosis; Humans; Hyaluronic Acid; Hydroxyproline; Injections, Intraperitoneal; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Serum Albumin | 2006 |
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.
Topics: Aging; Animals; Body Weight; Cobra Cardiotoxin Proteins; Disease Models, Animal; Fibrosis; Gene Deletion; Genotype; Hydroxyproline; Mice; Mice, Transgenic; Muscular Dystrophies, Limb-Girdle; Myostatin; Time Factors; Transforming Growth Factor beta | 2006 |
Effects of a static magnetic field on wound healing: results in experimental rat colon anastomoses.
Topics: Anastomosis, Surgical; Animals; Biomarkers; Colon, Descending; Disease Models, Animal; Electromagnetic Fields; Follow-Up Studies; Hydroxyproline; Male; Rats; Rats, Wistar; Wound Healing | 2006 |
Novel pirfenidone analogues: synthesis of pyridin-2-ones for the treatment of pulmonary fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Bleomycin; Bronchoalveolar Lavage Fluid; Creatinine; Dihydropyridines; Disease Models, Animal; Hydroxyproline; Intubation, Intratracheal; L-Lactate Dehydrogenase; Lung; Male; Molecular Structure; Pulmonary Fibrosis; Pyridones; Rats; Time Factors; Urea | 2006 |
Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline.
Topics: Animals; Calcium; Calcium Oxalate; Creatinine; Dinoprost; Disease Models, Animal; Gene Expression Regulation; Hyaluronan Receptors; Hydrogen Peroxide; Hydroxyproline; Hyperoxaluria; Immunohistochemistry; Kidney Calculi; Kidney Tubules; L-Lactate Dehydrogenase; Male; Osteopontin; Oxalates; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 2006 |
Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.
Topics: Animals; Cells, Cultured; Collagen; Dermis; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Fibrosis; Gene Expression; Humans; Hydroxyproline; Male; MAP Kinase Kinase 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Adenosine A2A; RNA, Messenger; Scleroderma, Diffuse; Triazines; Triazoles | 2006 |
[Kinetics and mechanism in bleomycin-induced murine pulmonary fibrosis model].
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Lung; Male; Mice; Mice, Inbred ICR; Pulmonary Fibrosis; Random Allocation; Th2 Cells; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2006 |
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.
Topics: Administration, Inhalation; Animals; Collagen; Cytokines; Disease Models, Animal; Hydroxyproline; Intubation, Intratracheal; Lung; Male; Mice; Mice, Inbred C57BL; Oropharynx; Pulmonary Fibrosis; Silicon Dioxide; Silicosis | 2006 |
Therapeutic effect of Chinese medicine formula DSQRL on experimental pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Lung; Male; Medicine, Chinese Traditional; Prednisone; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley | 2007 |
Effects of retinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice.
Topics: Animals; Collagen Type I; Disease Models, Animal; Gene Expression; Hydroxyproline; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Tretinoin | 2007 |
Coagulation factor Xa modulates airway remodeling in a murine model of asthma.
Topics: Amphiregulin; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Collagen; Disease Models, Animal; EGF Family of Proteins; Factor Xa; Factor Xa Inhibitors; Fondaparinux; Glycoproteins; Goblet Cells; Humans; Hydroxyproline; Hyperplasia; Intercellular Signaling Peptides and Proteins; Lung; Male; Mice; Mice, Inbred Strains; Mucins; Ovalbumin; Polysaccharides; Receptor, PAR-1; Receptor, PAR-2; Respiration; RNA, Messenger; Thrombin | 2007 |
Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Fatty Liver; Female; Hydroxyproline; Iron Overload; Lipid Peroxidation; Liver; Methionine; Organ Size; Rats; Rats, Inbred F344 | 2006 |
[Influence of propyl-thiouracil-induced hypothyroidism on rat gingival mucosa].
Topics: Animals; Antithyroid Agents; Collagen; Colorimetry; Disease Models, Animal; DNA; Gingiva; Hydroxyproline; Hypothyroidism; Male; Propylthiouracil; Proteins; Rats; Rats, Sprague-Dawley; Spectrophotometry; Thyroxine; Triiodothyronine | 2006 |
Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats.
Topics: Administration, Oral; Animals; Bleomycin; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Antibody Technique, Indirect; Herbal Medicine; Hydroxyproline; Immunohistochemistry; In Situ Hybridization; Lung; Male; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Specific Pathogen-Free Organisms; Time Factors; Transforming Growth Factor beta1 | 2007 |
Transient profound mesenteric ischemia strongly affects the strength of intestinal anastomoses in the rat.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Follow-Up Studies; Gelatinases; Hydroxyproline; Ileum; Male; Mesentery; Peroxidase; Pressure; Rats; Rats, Wistar; Reperfusion Injury; Treatment Outcome | 2007 |
Protective effect of verapamil on multiple hepatotoxic factors-induced liver fibrosis in rats.
Topics: Actins; Alanine Transaminase; Animals; Carbon Tetrachloride; Collagen; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Necrosis; Protective Agents; Rats; Rats, Wistar; Transforming Growth Factor beta1; Verapamil | 2007 |
Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Capillaria; Chronic Disease; Disease Models, Animal; Enoplida Infections; Female; Glucocorticoids; Hydroxyproline; Liver Cirrhosis, Experimental; Male; Prednisone; Rats; Rats, Wistar; Severity of Illness Index | 2006 |
Wound-healing activity of Morinda citrifolia fruit juice on diabetes-induced rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Granulation Tissue; Humans; Hydroxyproline; Male; Morinda; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; Skin Care; Streptozocin; Wound Healing; Wounds and Injuries | 2007 |
Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
Topics: Animals; Bile Ducts; Biomarkers; Cell Survival; Cells, Cultured; Disease Models, Animal; Epithelium; Hedgehog Proteins; Hydroxyproline; Kruppel-Like Transcription Factors; Kupffer Cells; Ligation; Liver; Liver Cirrhosis, Biliary; Mesoderm; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Zinc Finger Protein Gli2 | 2007 |
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.
Topics: Animals; Antigens, Viral; Arginase; beta-N-Acetylhexosaminidases; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Disease Progression; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Viral; Herpesviridae Infections; Hydroxyproline; Immunoassay; Intercellular Signaling Peptides and Proteins; Interferon gamma Receptor; Lectins; Mice; Nerve Growth Factor; Proteins; Pulmonary Fibrosis; Receptors, Interferon; Reverse Transcriptase Polymerase Chain Reaction; Rhadinovirus; RNA, Viral; Transforming Growth Factor beta; Tumor Virus Infections; Vascular Endothelial Growth Factor A; Viral Envelope Proteins; Virus Activation | 2007 |
A comparative study on several models of experimental renal calcium oxalate stones formation in rats.
Topics: Ammonium Chloride; Animals; Blood Urea Nitrogen; Calcium; Calcium Gluconate; Calcium Oxalate; Creatinine; Crystallization; Disease Models, Animal; Ethylene Glycol; Gentamicins; Hydroxycholecalciferols; Hydroxyproline; Kidney; Kidney Calculi; Magnesium; Male; Microscopy, Polarization; Oxalates; Phosphorus; Random Allocation; Rats; Rats, Wistar | 2007 |
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; Leukotriene Antagonists; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Leukotriene; Transforming Growth Factor beta | 2007 |
Evaluation of Tectona grandis leaves for wound healing activity.
Topics: Administration, Oral; Administration, Topical; Aloe; Animals; Burns; Chemistry, Pharmaceutical; Dermatologic Surgical Procedures; Disease Models, Animal; Drug Carriers; Drug Compounding; Gels; Granulation Tissue; Hot Temperature; Hydrochloric Acid; Hydroxyproline; Hypromellose Derivatives; Male; Methylcellulose; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Skin; Solvents; Verbenaceae; Wound Healing; Wounds, Penetrating | 2007 |
[Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Becaplermin; Benzamides; Bleomycin; Disease Models, Animal; Hydroxyproline; Imatinib Mesylate; Lung; Mice; Mice, Inbred C57BL; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pulmonary Fibrosis; Pyrimidines; Random Allocation | 2007 |
Anti-fibrotic effect of meloxicam in a murine lung fibrosis model.
Topics: Animals; Antioxidants; Bleomycin; Collagen; Cyclooxygenase Inhibitors; Disease Models, Animal; Glutathione; Hydroxyproline; Lipid Peroxidation; Male; Malondialdehyde; Meloxicam; Mice; Neovascularization, Pathologic; Peroxidase; Pulmonary Fibrosis; Superoxide Dismutase; Thiazines; Thiazoles | 2007 |
Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Random Allocation; Rats; Rats, Inbred F344; Rats, Wistar | 2007 |
Inhibitory effects of soy isoflavones on cardiovascular collagen accumulation in rats.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Cardiovascular System; Collagen; Disease Models, Animal; Disease Progression; Fibrosis; Heart Rate; Hydroxyproline; Isoflavones; Lipid Metabolism; Male; Myocardium; Organ Size; Oxidative Stress; Phytoestrogens; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Severity of Illness Index; Soy Foods | 2007 |
Effects of a membrane-permeable radical scavenger, Tempol, on healing of colonic anastomoses in the cecal ligation and puncture model of polymicrobial sepsis in rats.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Biomarkers; Colon; Cyclic N-Oxides; Disease Models, Animal; Follow-Up Studies; Glutathione; Hydroxyproline; Laparotomy; Ligation; Lipid Peroxidation; Male; Malondialdehyde; Peroxidase; Postoperative Complications; Punctures; Rats; Rats, Wistar; Sepsis; Spectrophotometry; Spin Labels; Wound Healing | 2007 |
An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination; Herbicides; HSP47 Heat-Shock Proteins; Hydroxyproline; Immunoenzyme Techniques; Intubation, Intratracheal; Lung; Male; Oligonucleotides, Antisense; Paraquat; Pulmonary Fibrosis; Rats; Rats, Wistar | 2007 |
Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty Liver; Hydroxyproline; Liver Cirrhosis; Liver Function Tests; Losartan; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Pyrrolidine dithiocarbamate prevents deleterious effects of remote ischemia/reperfusion injury on healing of colonic anastomoses in rats.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Colon; Colonic Diseases; Disease Models, Animal; Glutathione; Hydroxyproline; Male; Malondialdehyde; Peroxidase; Pyrrolidines; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Thiocarbamates; Wound Healing | 2007 |
A new murine model for bronchiolitis obliterans post-bone marrow transplant.
Topics: Animals; Bone Marrow Transplantation; Bronchiolitis Obliterans; Chemokines; Cytokines; Disease Models, Animal; Graft vs Host Disease; Hydroxyproline; Inflammation Mediators; Lung; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; T-Lymphocytes; Transplantation Conditioning; Transplantation, Homologous | 2007 |
Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents; Clostridium histolyticum; Disease Models, Animal; Hydroxyproline; Male; Microbial Collagenase; Mitomycin; Peritoneal Cavity; Rats; Rats, Wistar; Tissue Adhesions | 2007 |
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Cholangitis, Sclerosing; Cholesterol; Dicarbethoxydihydrocollidine; Disease Models, Animal; Glutathione; Hydroxyproline; Immunohistochemistry; In Situ Hybridization; Liver; Liver Cirrhosis, Biliary; Male; Mice; Models, Biological; Multidrug Resistance-Associated Proteins; Osteopontin; Phospholipids; Time Factors; Tumor Necrosis Factor-alpha; Xenobiotics | 2007 |
A prolonged interval between deep intestinal ischemia and anastomotic construction does not impair wound strength in the rat.
Topics: Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Ileum; Ischemia; Male; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Splanchnic Circulation; Surgical Wound Dehiscence; Tensile Strength; Time Factors; Wound Healing | 2007 |
Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Bronchopulmonary Dysplasia; Cathepsins; Collagen; Desmosine; Disease Models, Animal; Elastin; Humans; Hydroxyproline; Hyperoxia; Infant, Newborn; Lung; Lung Injury; Macrophages, Alveolar; Mice; Proteins; Pulmonary Alveoli; RNA, Messenger | 2007 |
Wound healing activity of Matricaria recutita L. extract.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Matricaria; Phytotherapy; Plant Preparations; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds and Injuries | 2007 |
Treatment of chronic liver injuries in mice by oral administration of ethanolic extract of the fruit of Hovenia dulcis.
Topics: Administration, Oral; Animals; Aspartate Aminotransferase, Cytoplasmic; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Collagen Type I; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Lipid Peroxidation; Liver; Male; Methionine Adenosyltransferase; Mice; Mice, Inbred ICR; Phytotherapy; Rhamnaceae | 2007 |
Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury.
Topics: Animals; Ascorbic Acid; Benzoates; Central Nervous System Depressants; Collagen; Disease Models, Animal; Ethanol; Fluorescence; Hemidesmus; Hydroxyproline; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Plant Roots; Rats; Rats, Wistar | 2007 |
Dietary oxalate and calcium oxalate nephrolithiasis.
Topics: Animals; Calcium Oxalate; Creatinine; Dietary Supplements; Disease Models, Animal; Follow-Up Studies; Hydrogen-Ion Concentration; Hydroxyproline; Hyperoxaluria; Kidney; Male; Microscopy, Electron, Scanning; Nephrolithiasis; Rats; Rats, Sprague-Dawley; Urine | 2007 |
Role of allopurinol on oxidative stress in caustic burn: cure for stricture?
Topics: Allopurinol; Animals; Biomarkers; Burns, Chemical; Caustics; Disease Models, Animal; Esophageal Stenosis; Esophagus; Free Radical Scavengers; Glutathione; Hydroxyproline; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Spectrophotometry; Treatment Outcome; Xanthine Oxidase | 2007 |
Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Fosinopril; Glutathione; Hydroxyproline; Lipid Peroxidation; Lisinopril; Liver; Liver Cirrhosis; Liver Function Tests; Losartan; Male; Oxidative Stress; Rats; Renin-Angiotensin System | 2008 |
Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Biomarkers; Body Weight; Calcium; Cathepsin K; Cathepsins; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Activation; Female; Femur; Gene Expression Regulation, Enzymologic; Glucose; Hydroxyproline; Isoenzymes; Osteocalcin; Rats; Rats, Wistar; RNA, Messenger; Streptozocin; Tartrate-Resistant Acid Phosphatase | 2007 |
Topical diphenylhydantoin sodium can improve healing in a diabetic incisional animal wound model.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Evaluation, Preclinical; Hydroxyproline; Immunohistochemistry; Injections, Intradermal; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spectrophotometry; Streptozocin; Tensile Strength; Treatment Outcome; Wound Healing; Wounds, Penetrating | 2007 |
An evaluation of normal saline and taurolidine on intra-abdominal adhesion formation and peritoneal fibrinolysis.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Female; Fibrinolysis; Hydroxyproline; Peritoneum; Plasminogen Activator Inhibitor 1; Postoperative Complications; Rats; Rats, Wistar; Sodium Chloride; Taurine; Therapeutic Irrigation; Thiadiazines; Tissue Adhesions; Tissue Plasminogen Activator | 2008 |
[Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model].
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Paraquat; Placenta Growth Factor; Pregnancy Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2007 |
[Effects of reduced glutathione on contents of hydroxyproline and oxidation stress reaction in kidney of unilateral ureteral obstruction in rat].
Topics: Animals; Disease Models, Animal; Female; Glutathione; Hydroxyproline; Kidney; Male; Malondialdehyde; Nephrosclerosis; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Ureteral Obstruction | 2007 |
Effectiveness of etanercept in bleomycin-induced experimental scleroderma.
Topics: Animals; Antirheumatic Agents; Bleomycin; Cytokines; Disease Models, Animal; Etanercept; Female; Hydroxyproline; Immunoglobulin G; Mice; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor; Scleroderma, Localized; Skin | 2008 |
Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Body Weight; Cluster Analysis; Collagen; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Lung; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factors | 2007 |
Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Division; Chemokine CXCL2; Chemokines; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Neutrophils; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pancreatic Elastase; Proliferating Cell Nuclear Antigen; Pulmonary Alveoli; Pulmonary Emphysema; Recovery of Function; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2008 |
Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Body Weight; Collagen; Desmosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Elastin; Electric Stimulation; Erectile Dysfunction; Extracellular Matrix; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myography; Organ Size; Penis; Phenylephrine; Polymerase Chain Reaction; Receptors, Leptin; Regional Blood Flow; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins | 2008 |
Biochemical and histopathologic effects of omeprazole and vitamin E in rats with corrosive esophageal burns.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Burns, Chemical; Disease Models, Animal; Drug Therapy, Combination; Esophagus; Glutathione; Hydroxyproline; Injections, Intramuscular; Injections, Intraperitoneal; Malondialdehyde; Omeprazole; Rats; Rats, Wistar; Treatment Outcome; Vitamin E | 2008 |
Wound healing activity of Persea americana (avocado) fruit: a preclinical study on rats.
Topics: Administration, Cutaneous; Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Drug Evaluation; Fruit; Granulation Tissue; Hydroxyproline; Male; Ointments; Persea; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds, Penetrating | 2008 |
Comparison between conventional and "clinical" assessment of experimental lung fibrosis.
Topics: Adenoviridae; Animals; Collagen; Disease Models, Animal; Disease Progression; Female; Gene Transfer Techniques; Hydroxyproline; Lung; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Time Factors; Tomography, X-Ray Computed; Transforming Growth Factors | 2008 |
Reproducible long-term disc degeneration in a large animal model.
Topics: Animals; Chondroitin ABC Lyase; Chronic Disease; Disease Models, Animal; Female; Glycosaminoglycans; Goats; Hydroxyproline; Injections, Spinal; Intervertebral Disc; Magnetic Resonance Imaging; Osteophyte; Radiography; Reproducibility of Results; Severity of Illness Index; Spinal Diseases; Time Factors | 2008 |
Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition.
Topics: Animals; Arginine; Calcium Oxalate; Crystallization; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyproline; Hyperoxaluria; Kidney; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides | 2008 |
Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bleomycin; Blood Cell Count; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Imidazoles; Macrophage Inflammatory Proteins; Male; Mice; Mice, Inbred ICR; Pulmonary Fibrosis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2008 |
Enzymuria (the output of gamma-glutamyl-transpeptidase and of N-acetyl-beta-D-glucosaminidase) in the course of experimental renovascular hypertension.
Topics: Acetylglucosaminidase; Animals; Blood Pressure; Disease Models, Animal; Female; gamma-Glutamyltransferase; Hexosaminidases; Hydroxyproline; Hypertension, Renal; Hypertension, Renovascular; Kidney; Male; Membranes; Rats; Sex Factors | 1981 |
Carbon tetrachloride-induced hepatic fibrosis and cirrhosis in the developing rat: an experimental model of cirrhosis in childhood.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Phenobarbital; Procollagen-Proline Dioxygenase; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Auricular chondritis in fawn-hooded rats. A spontaneous disorder resembling that induced by immunization with type II collagen.
Topics: Animals; Cartilage Diseases; Collagen; Diagnosis, Differential; Disease Models, Animal; DNA; Ear Cartilage; Ear, External; Female; Hybridization, Genetic; Hydroxyproline; Immunization; Polychondritis, Relapsing; Procollagen-Proline Dioxygenase; Proteins; Rats; Rats, Inbred Strains | 1984 |
Functional and biochemical indicators of pneumoconiosis in mice: comparison with rats.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Lung Volume Measurements; Mice; Organ Size; Pneumoconiosis; Rats; Species Specificity | 1984 |
Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Hydroxyproline; Mice; Mice, Mutant Strains; Organ Culture Techniques; Proline; Scleroderma, Systemic; Skin | 1984 |
[An experimental model of osteoarthritis. II.- Biochemical study of collagen and proteoglycans].
Topics: Animals; Cartilage, Articular; Chemical Phenomena; Chemistry; Collagen; Disease Models, Animal; Hydroxyproline; Osteoarthritis; Papain; Proline; Proteoglycans; Rabbits | 1984 |
Correlation between Ito cells and fibrogenesis in an experimental model of hepatic fibrosis. A sequential stereological study.
Topics: Animals; Cell Count; Disease Models, Animal; Fibroblasts; Hydroxyproline; Liver; Liver Cirrhosis; Male; Rats; Rats, Inbred Strains | 1983 |
The effect of chronic alcoholism on wound healing.
Topics: Alcoholism; Animals; Disease Models, Animal; Granuloma; Humans; Hydroxyproline; Male; Mice; Skin; Tensile Strength; Wound Healing | 1981 |
Plasma free hydroxyproline, growth, and sexual maturity in the scoliotic chicken.
Topics: Animals; Chickens; Collagen; Disease Models, Animal; Female; Growth; Hydroxyproline; Male; Poultry Diseases; Scoliosis; Sexual Maturation | 1980 |
Pathophysiology of congenital diaphragmatic hernia. XI: Anatomic and biochemical characterization of the heart in the fetal lamb CDH model.
Topics: Animals; Aorta; Blood Pressure; Collagen; Disease Models, Animal; DNA; Ductus Arteriosus, Patent; Elastin; Female; Heart Atria; Heart Defects, Congenital; Heart Septal Defects, Atrial; Heart Septum; Heart Ventricles; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hydroxyproline; Organ Size; Pregnancy; Proteins; Pulmonary Artery; Sheep | 1995 |
Pathophysiology of congenital diaphragmatic hernia. XVI: Elevated pulmonary collagen in the lamb model of congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Bronchi; Collagen; Disease Models, Animal; DNA; Elastin; Female; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hydroxyproline; Infant, Newborn; Intestines; Kidney; Lung; Lung Compliance; Persistent Fetal Circulation Syndrome; Pregnancy; Proteins; Pulmonary Surfactants; Sheep; Venules | 1995 |
Suppressive effect of anti-alpha 1-antichymotrypsin serum on pulmonary fibrosis induced by phorbol myristate acetate in vivo.
Topics: alpha 1-Antichymotrypsin; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Cells, Cultured; Collagen; Dimethyl Sulfoxide; Disease Models, Animal; Hydroxyproline; Lung; Macrophages, Alveolar; Pulmonary Fibrosis; Rabbits; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1995 |
Dose and regimen effects of poly ICLC, an interferon inducer, in a multi-dose bleomycin model of interstitial pulmonary fibrosis.
Topics: Animals; Bleomycin; Carboxymethylcellulose Sodium; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxyproline; Injections, Intraperitoneal; Interferon Inducers; Lipid Peroxidation; Lung; Male; Mesocricetus; Poly I-C; Polylysine; Procollagen-Proline Dioxygenase; Pulmonary Fibrosis; Superoxide Dismutase; Weight Gain | 1994 |
Heterogeneous decrease of bone mineral density in the vertebral column of ovariectomized rats.
Topics: Absorptiometry, Photon; Alkaline Phosphatase; Analysis of Variance; Animals; Body Weight; Bone Density; Bone Development; Bone Resorption; Calcium; Creatinine; Disease Models, Animal; Estradiol; Estrogens; Female; Humans; Hydroxyproline; Lumbar Vertebrae; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Wistar; Spine; Tail | 1995 |
Effects of angiotensin-converting enzyme inhibitor and aldosterone antagonist on myocardial collagen in cardiomyopathic hamsters.
Topics: Aging; Animals; Body Weight; Canrenoic Acid; Captopril; Cardiomyopathies; Collagen; Cricetinae; Disease Models, Animal; Heart; Hydroxyproline; Male; Organ Size | 1995 |
The anabolic effect of human PTH (1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate--is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?
Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Density; Bone Development; Bone Resorption; Diphosphonates; Disease Models, Animal; Female; Humans; Hydroxyproline; Ilium; Injections, Subcutaneous; Osteocalcin; Osteoclasts; Osteoporosis, Postmenopausal; Parathyroid Hormone; Peptide Fragments; Sheep; Teriparatide | 1995 |
Peripheral vascular alterations during experimental heart failure in the rat. Do they exist?
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Flow Velocity; Blood Vessels; Cardiac Output, Low; Carotid Arteries; Coronary Vessels; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Ligation; Male; Mesenteric Arteries; Myocardial Infarction; Pulmonary Artery; Rats; Rats, Wistar; Renal Artery | 1995 |
Correlation between high resolution computed tomography and tissue morphometry of the lung in bleomycin-induced pulmonary fibrosis in the rabbit.
Topics: Analysis of Variance; Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Oxygen; Pulmonary Fibrosis; Rabbits; Regression Analysis; Time Factors; Tomography, X-Ray Computed | 1993 |
Streptozotocin and alloxan are comparable agents in the diabetic model of impaired wound healing.
Topics: Alloxan; Analysis of Variance; Animals; Collagenases; Diabetes Mellitus, Experimental; Disease Models, Animal; Hydroxyproline; Male; Rats; Rats, Sprague-Dawley; Streptozocin; Wound Healing | 1993 |
Parathyroidectomy does not prevent bone loss in the oophorectomized rat.
Topics: Alkaline Phosphatase; Animals; Bone Density; Calcium; Disease Models, Animal; Female; Femur; Hydroxyproline; Osteocalcin; Osteoporosis; Ovariectomy; Parathyroidectomy; Rats; Rats, Sprague-Dawley | 1994 |
Hapten-immune pulmonary interstitial fibrosis (HIPIF) in mice requires both CD4+ and CD8+ T lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Haptens; Hydroxyproline; Immunotherapy, Adoptive; Lung; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; T-Lymphocytes; Trinitrobenzenes | 1993 |
Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.
Topics: Amino Acids; Animals; Choline Deficiency; Diet; Disease Models, Animal; Glutathione Transferase; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Procollagen-Proline Dioxygenase; Prodrugs; Pyridines; Rats; Rats, Wistar | 1994 |
Consequences of prolonged inhalation of ozone on Fischer-344/N rats: collaborative studies. Part I: Content and cross-linking of lung collagen.
Topics: Air Pollutants; Animals; Chronic Disease; Collagen; Cross-Linking Reagents; Disease Models, Animal; DNA; Female; Hydroxyproline; Male; Organ Size; Ozone; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Severity of Illness Index; Time Factors | 1994 |
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Hydroxyproline; Injections, Intraperitoneal; Liver; Lung; Male; Mesocricetus; Organ Size; Pulmonary Fibrosis; Tissue Distribution | 1994 |
Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: application to the study of intravenous 14C-labeled 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate.
Topics: Animals; Bone Resorption; Creatinine; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxyproline; Injections, Intravenous; Male; Pyrrolidines; Rats; Rats, Wistar | 1994 |
Surgically induced uremia in rats. I: Effect on bone strength and metabolism.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Cholecalciferol; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Female; Hydroxyproline; Hyperparathyroidism, Secondary; Nephrectomy; Parathyroid Hormone; Rats; Rats, Wistar; Second Messenger Systems; Stress, Mechanical; Uremia | 1993 |
A novel in vivo model for the study of cartilage degradation.
Topics: Animals; Cartilage Diseases; Cartilage, Articular; Cattle; Disease Models, Animal; Hydroxyproline; In Vitro Techniques; Irritants; Nasal Septum; Proteoglycans | 1993 |
A new model of progressive pulmonary fibrosis in rats.
Topics: Administration, Inhalation; Animals; Collagen; Desmosine; Disease Models, Animal; DNA; Elastin; Environmental Exposure; Hydroxyproline; Lung; Male; Nitrogen Dioxide; Ozone; Proteins; Pulmonary Fibrosis; Pyridines; Rats; Rats, Sprague-Dawley; Survival Rate | 1993 |
Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis.
Topics: Animals; Collagen; Disease Models, Animal; Female; Fibrosis; Gelatin Sponge, Absorbable; Humans; Hydroxyproline; Mice; Mice, Inbred BALB C; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Relaxin | 1993 |
Immunological characterization of (tight skin/NZB)F1 hybrid mice with connective tissue and autoimmune features resembling human systemic sclerosis.
Topics: Animals; Autoantibodies; Collagen; Connective Tissue; Cytokines; Disease Models, Animal; Hydroxyproline; Lymphocyte Activation; Mice; Mice, Inbred NZB; Mice, Mutant Strains; Organ Culture Techniques; Scleroderma, Systemic; Skin; T-Lymphocytes | 1993 |
Dose dependency and wound healing aspects of the use of tissue plasminogen activator in the prevention of intra-abdominal adhesions.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Ischemia; Ligation; Peritoneum; Pilot Projects; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Tissue Plasminogen Activator; Wound Healing | 1993 |
Circulating levels and bone contents of bone gamma-carboxyglutamic acid-containing protein in rat models of non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Bone and Bones; Bone Diseases, Metabolic; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydroxyproline; Insulin; Male; Organ Size; Osteocalcin; Rats; Rats, Wistar; Streptozocin | 1993 |
The use of angiostatic steroids to inhibit cartilage destruction in an in vivo model of granuloma-mediated cartilage degradation.
Topics: Animals; Cartilage; Cortisone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Granuloma; Heparin; Hydroxyproline; Rats; Rats, Wistar | 1993 |
Amiodarone-induced pulmonary fibrosis in Fischer 344 rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Carbon Monoxide; Diffusion; Disease Models, Animal; Female; Hydroxyproline; Lung; Plethysmography; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Respiratory Function Tests; Staining and Labeling; Trachea | 1996 |
[Collagen metabolism disturbances with experimentally increased pulmonary flow--experimental model of left to right shunt with congenital heart defects in children].
Topics: Anastomosis, Surgical; Animals; Biopsy; Collagen; Disease Models, Animal; Female; Heart Defects, Congenital; Hydroxyproline; Lung; Male; Pulmonary Circulation; Swine | 1995 |
Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis.
Topics: Animals; Cholestasis; Disease Models, Animal; Female; Humans; Hydroxyproline; Liver Cirrhosis, Experimental; Peptide Fragments; Procollagen; Rats; Rats, Wistar | 1996 |
Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats.
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Bone Density; Bone Resorption; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Replacement Therapy; Female; Femur; Humans; Hydroxyproline; Injections, Subcutaneous; Osteoblasts; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence | 1996 |
Acute protein-calorie malnutrition impairs wound healing: a possible role of decreased wound nitric oxide synthesis.
Topics: Acute Disease; Amino Acids; Animals; Cells, Cultured; Collagen; Disease Models, Animal; DNA; Hydroxyproline; Nitrates; Nitric Oxide; Nitrites; Protein-Energy Malnutrition; Rats; Rats, Sprague-Dawley; RNA, Messenger; Wound Healing | 1997 |
Ischemia and reperfusion of the porcine myocardium: effect on collagen.
Topics: Analysis of Variance; Animals; Biomarkers; Collagen; Collagen Type I; Creatine Kinase; Disease Models, Animal; Hemodynamics; Hydroxyproline; Microscopy, Electron; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Peptides; Procollagen; Swine | 1997 |
Bilateral tibial marrow ablation in rats induces a rapid hypercalcemia arising from extratibial bone resorption inhibitable by methylprednisolone or deflazacort.
Topics: alpha-Macroglobulins; Animals; Bone Marrow; Bone Resorption; Calcium; Disease Models, Animal; Fracture Healing; Hydroxyproline; Hypercalcemia; Male; Methylprednisolone; Pregnenediones; Rats; Rats, Sprague-Dawley; Tibia | 1997 |
Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat.
Topics: Aging; Animals; Colchicine; Disease Models, Animal; Fibrosis; Heart; Hydroxyproline; Hypertension; Male; Muscle Contraction; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1997 |
Effects of 72 hours sleep deprivation on wound healing in the rat.
Topics: Animals; Biopsy; Disease Models, Animal; DNA; Fibroblasts; Granulocytes; Hydroxyproline; Macrophages; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Wound Healing | 1997 |
Extensive damage to the end-plates as a complication of laser discectomy. An experimental study using an animal model.
Topics: Animals; Cartilage, Articular; Cervical Vertebrae; Disease Models, Animal; Diskectomy; Guinea Pigs; Hydroxyproline; Intervertebral Disc; Intervertebral Disc Displacement; Intraoperative Complications; Laser Therapy; Male | 1997 |
Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Disease Models, Animal; Fibrosis; Hydroxyproline; Lung; Lung Diseases, Interstitial; Male; Mice; Mice, Inbred ICR; Phosphatidylcholines; Recombinant Proteins; Superoxide Dismutase | 1997 |
The use of Chinese herbal medicine on experimental fracture healing.
Topics: Administration, Oral; Administration, Topical; Animal Feed; Animals; Body Weight; Collagen; Disease Models, Animal; DNA; Drugs, Chinese Herbal; Fracture Healing; Hydroxyproline; Random Allocation; Rats; RNA; Tibia; Tibial Fractures | 1997 |
Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Erythromycin; Female; Hydroxyproline; Lung; Macrophage Activation; Macrophages, Alveolar; Platelet-Derived Growth Factor; Pulmonary Fibrosis; Rats; Rats, Wistar; Reference Values; Tumor Necrosis Factor-alpha | 1997 |
[Effects of diacerhein on cytokine determinations in a model of cartilage degradation induced by granuloma in mice].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; Disease Models, Animal; Glycosaminoglycans; Granuloma; Hydroxyproline; Mice; Mice, Transgenic; Osteoarthritis | 1997 |
Staphylococcal septic arthritis: antibiotic and nonsteroidal anti-inflammatory drug treatment in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Cartilage, Articular; Ceftriaxone; Cephalosporins; Dinoprostone; Disease Models, Animal; Drug Therapy, Combination; Female; Glycosaminoglycans; Hydroxyproline; Knee Joint; Naproxen; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Synovial Fluid; Synovitis | 1997 |
Effects of oxaceprol on the microcirculation in ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cell Adhesion; Cricetinae; Dextrans; Disease Models, Animal; Fluorescein-5-isothiocyanate; Hydroxyproline; Leukocytes; Mesocricetus; Microcirculation; Muscle, Skeletal; Reperfusion Injury; Skin | 1998 |
Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Granuloma; Hydroxyproline; Lung; Lung Diseases, Fungal; Male; Mice; Mice, Inbred BALB C; Paracoccidioides; Paracoccidioidomycosis; Pulmonary Fibrosis; Specific Pathogen-Free Organisms; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1998 |
Pirfenidone improves renal function and fibrosis in the post-obstructed kidney.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Collagen; Disease Models, Animal; Fibrosis; Gelatinases; Hydroxyproline; Inulin; Kidney Cortex; Kidney Function Tests; Ligation; Male; Matrix Metalloproteinase 2; Metalloendopeptidases; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Ribosomal, 18S; RNA, Ribosomal, 28S; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 1998 |
Glycoprotein composition in cyclophosphamide-induced lung fibrosis.
Topics: Animals; Cyclophosphamide; Disease Models, Animal; Endopeptidases; Fibrosis; Glycoproteins; Glycosyltransferases; Hydroxyproline; Lung; Male; Monosaccharides; Rats; Rats, Wistar | 1998 |
Production of superoxide and nitric oxide by alveolar macrophages in the bleomycin-induced interstitial pneumonia mice model.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Lung; Lung Diseases, Interstitial; Macrophages, Alveolar; Mice; Nitric Oxide; Superoxides; Tyrosine | 1998 |
The preventive effect of heparin on stricture formation after caustic esophageal burns.
Topics: Animals; Burns, Chemical; Caustics; Disease Models, Animal; Esophageal Stenosis; Esophagus; Heparin; Hydroxyproline; Lye; Rats; Statistics, Nonparametric | 1999 |
Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908).
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Desmosine; Disease Models, Animal; Elastin; Hydroxamic Acids; Hydroxyproline; Injections, Intra-Arterial; Injections, Subcutaneous; Male; Metalloendopeptidases; Pancreatic Elastase; Pharmaceutical Vehicles; Protease Inhibitors; Rats; Rats, Wistar | 1999 |
[Effect of KW-8232 on bone turnover in ovariectomized rats].
Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Bone Resorption; Calcium; Disease Models, Animal; Female; Humans; Hydroxyproline; Indoles; Mesylates; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley | 1998 |
The influence of hypothyroidism on wound healing. An experimental study.
Topics: Animals; Biomarkers; Collagen; Disease Models, Animal; Hydroxyproline; Hypothyroidism; Male; Rats; Rats, Wistar; Thyroidectomy | 1999 |
Advanced glycation in D-galactose induced mouse aging model.
Topics: Aging; Animals; Avoidance Learning; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Female; Galactose; Glucose; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Interleukin-2; Learning; Lymphocytes; Lysine; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Nervous System Diseases; Skin; Superoxide Dismutase | 1999 |
Dimethylnitrosamine-induced hepatic cirrhosis: a new canine model of an ancient human disease.
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Female; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lymphatic System; Male; Portal System | 1970 |
Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Injections, Intravenous; Mannitol; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Phosphatidylcholines; Scleroderma, Localized; Scleroderma, Systemic; Skin; Superoxide Dismutase | 1999 |
Animal model of sclerotic skin. II. Bleomycin induced scleroderma in genetically mast cell deficient WBB6F1-W/W(V) mice.
Topics: Animals; Antibiotics, Antineoplastic; Biopsy; Bleomycin; Cell Count; Disease Models, Animal; Female; Fibrosis; Histamine; Hydroxyproline; Interleukin-4; Mast Cells; Mice; Mice, Mutant Strains; Scleroderma, Systemic; Sclerosis; Skin; Tumor Necrosis Factor-alpha | 1999 |
Alteration in aortic wall stiffness and accumulation of collagen during the prediabetic stage of type II diabetes mellitus in rats.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Tolerance Test; Histocytochemistry; Hydroxyproline; Insulin; Male; Observer Variation; Prediabetic State; Rats; Rats, Inbred Strains | 1999 |
Hepatic fibrogenesis using chronic arsenic ingestion: studies in a murine model.
Topics: Animals; Arsenic; Collagen; Disease Models, Animal; Hydroxyproline; Liver Cirrhosis, Experimental; Mice; Proteins | 1999 |
A time course study for the development of an immunocompromised wound model, using hydrocortisone.
Topics: Adrenal Glands; Animals; Cell Division; Disease Models, Animal; DNA; Hydrocortisone; Hydroxyproline; Immunocompromised Host; Leukocytes; Male; Mononuclear Phagocyte System; Proteins; Rats; Rats, Sprague-Dawley; Skin; Spleen; Tensile Strength; Time Factors; Wound Healing | 1999 |
The effect of octreotide on postoperative adhesion formation.
Topics: Animals; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrinolysis; Growth Substances; Hydroxyproline; Ileal Diseases; Injections, Subcutaneous; Linear Models; Male; Mice; Octreotide; Postoperative Complications; Severity of Illness Index; Time Factors; Tissue Adhesions; Wound Healing | 2000 |
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Ascites; Aspartate Aminotransferases; Bilirubin; Cholestasis; Collagen; Disease Models, Animal; DNA, Complementary; Endothelin Receptor Antagonists; Endothelin-1; Female; Hydroxyproline; Hypertension, Portal; Jaundice; Liver; Liver Cirrhosis, Experimental; Organ Size; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2000 |
Heart failure development in rats with ascending aortic constriction and angiotensin-converting enzyme inhibition.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiac Output, Low; Collagen; Disease Models, Animal; Hydroxyproline; Isoquinolines; Male; Peptidyl-Dipeptidase A; Quinapril; Rats; Rats, Wistar; Tetrahydroisoquinolines; Treatment Outcome; Vasoconstriction | 2000 |
The ethanol-soluble part of a hot-water extract from Artemisia iwayomogi inhibits liver fibrosis induced by carbon tetrachloride in rats.
Topics: Animals; Artemisia; Carbon Tetrachloride; Disease Models, Animal; Ethanol; Hot Temperature; Hydroxyproline; Liver Cirrhosis; Male; Malondialdehyde; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Water | 2000 |
The Fas/Fas-ligand system is not required for bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Hydroxyproline; In Situ Nick-End Labeling; Lung; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis | 2000 |
Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Niacin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Fibrosis; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Taurine | 2000 |
Effect of diacetyl rhein on the development of experimental osteoarthritis. A biochemical investigation.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cartilage, Articular; Cells, Cultured; Chondroitin Sulfates; Disease Models, Animal; Dogs; Epitopes; Glycosaminoglycans; Hydroxyproline; Osteoarthritis; Proteoglycans | 1996 |
Hepatocyte growth factor attenuates collagen accumulation in a murine model of pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Bleomycin; Cells, Cultured; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatocyte Growth Factor; Humans; Hydroxyproline; Immunohistochemistry; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Recombinant Proteins; Specific Pathogen-Free Organisms | 2000 |
Effect of pyloric drainage on the healing of esophagogastric anastomoses in rats.
Topics: Anastomosis, Surgical; Animals; Disease Models, Animal; Drainage; Esophagectomy; Esophagus; Female; Gastric Juice; Gastrostomy; Hydroxyproline; Postoperative Complications; Pylorus; Rats; Rats, Sprague-Dawley; Stomach; Suture Techniques; Tensile Strength; Wound Healing | 2000 |
Immunoglobulin responses to experimental silicosis.
Topics: Administration, Inhalation; Animals; B-Lymphocyte Subsets; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Flow Cytometry; Hydroxyproline; Immunoglobulin G; Immunoglobulin M; Inhalation Exposure; Lung; Lymph Nodes; Male; Organ Size; Rats; Rats, Inbred F344; Silicon Dioxide; Silicosis; Spleen; Titanium | 2001 |
Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Catecholamines; Collagen; Diastole; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Endothelin-1; Gene Expression; Heart Failure; Heart Function Tests; Hydroxyproline; Myocardium; Myosin Heavy Chains; Organ Size; Rats; Rats, Inbred Dahl; Receptors, Angiotensin; RNA, Messenger; Sodium Chloride, Dietary; Survival Rate; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2001 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collagen; Constriction, Pathologic; Disease Models, Animal; Echocardiography; Hydroxyproline; Hypertrophy, Left Ventricular; In Vitro Techniques; Isoproterenol; Male; Myocardium; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Regression Analysis; Systole; Ventricular Dysfunction, Left; Ventricular Remodeling | 2001 |
CD40/CD40 ligand interactions are critical for elicitation of autoimmune-mediated fibrosis in the lung.
Topics: Animals; Antibodies, Blocking; Autoimmune Diseases; Bronchoalveolar Lavage Fluid; CD40 Antigens; CD40 Ligand; Cell Movement; Cytokines; Dendritic Cells; Disease Models, Animal; Female; Haptens; Hydroxyproline; Injections, Intraperitoneal; Interleukin-12; Intubation, Intratracheal; Mice; Mice, Inbred BALB C; Mice, Knockout; Monocytes; Pulmonary Fibrosis; Trinitrobenzenesulfonic Acid; Up-Regulation | 2001 |
Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemotaxis; Disease Models, Animal; Female; Hydroxyproline; Intracellular Signaling Peptides and Proteins; Lung; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; rho GTP-Binding Proteins; rho-Associated Kinases | 2001 |
Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Disease Models, Animal; Hydroxyproline; Inflammation; Lung; Macrophages, Alveolar; Male; Mice; Mice, Inbred ICR; Osteopontin; Pulmonary Fibrosis; Recombinant Fusion Proteins; RNA, Messenger; Sialoglycoproteins; Time Factors; Transcription, Genetic | 2001 |
Rat model of lung fibrosis: comparison of functional, biochemical, and histopathological changes 4 months after single irradiation of the right hemithorax.
Topics: Airway Resistance; Animals; Disease Models, Animal; Histocytochemistry; Hydroxyproline; Lung; Lung Volume Measurements; Peak Expiratory Flow Rate; Pulmonary Fibrosis; Radiation Pneumonitis; Rats; Rats, Inbred F344; Tidal Volume | 2001 |
Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Crystallization; Disease Models, Animal; Flow Cytometry; Gene Expression; Hydroxyproline; Immunoglobulin G; Interferon-gamma; Interleukin-4; Interleukin-9; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pulmonary Fibrosis; Recombinant Proteins; Silicon Dioxide; Th1 Cells; Th2 Cells | 2001 |
Pulmonary fibrosis is increased in mice carrying the factor V Leiden mutation following bleomycin injury.
Topics: Activated Protein C Resistance; Animals; Bleomycin; Disease Models, Animal; Factor V; Hydroxyproline; Lung; Male; Mice; Mice, Transgenic; Pneumonia; Point Mutation; Pulmonary Fibrosis | 2001 |
Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model.
Topics: Animals; Capillaria; Case-Control Studies; Disease Models, Animal; Female; Hydroxyproline; Immunologic Factors; Interferon-alpha; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar | 2001 |
Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Circadian Rhythm; Collagen; Collagen Type I; Disease Models, Animal; Female; Humans; Hydroxyproline; Melatonin; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptides; Procollagen; Rats; Rats, Wistar | 2001 |
Attenuation of bleomycin-induced pneumopathy in mice by monoclonal antibody to interleukin-12.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Hydroxyproline; Immunity, Cellular; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-12; Lung; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; RNA, Messenger; Th1 Cells; Th2 Cells | 2001 |
Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; C-Reactive Protein; Collagen; Daclizumab; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hydroxyproline; Immunization; Immunoglobulin G; Macaca mulatta; Male; Receptors, Interleukin-2; Weight Loss | 2001 |
Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse.
Topics: Animals; Bleomycin; Blood Coagulation; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Female; Fibrinolysis; Hydroxyproline; Interleukin-1; Intubation, Intratracheal; Lung; Mice; Mice, Inbred C57BL; Protein C; Proteins; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Thrombin; Tumor Necrosis Factor-alpha | 2001 |
Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Immunohistochemistry; Insulin-Like Growth Factor I; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Malondialdehyde; Procollagen-Proline Dioxygenase; Rats; Rats, Wistar; RNA, Messenger | 2001 |
Oxaceprol, an atypical inhibitor of inflammation, reduces leukocyte adherence in mouse antigen-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Cell Adhesion; Disease Models, Animal; Female; Hydroxyproline; Leukocytes; Mice; Mice, Inbred BALB C; Microcirculation; Synovial Membrane | 2001 |
Temporary warm ischaemia, 5/6 nephrectomy and single uranyl nitrate administration--comparison of three models intended to cause renal fibrosis in rats.
Topics: Animals; Creatinine; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Kidney; Nephrectomy; Nephritis, Interstitial; Proteinuria; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Uranyl Nitrate | 2001 |
Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction.
Topics: Animals; Collagen; Dilatation, Pathologic; Disease Models, Animal; Echocardiography; Enzyme Inhibitors; Female; Fibrosis; Heart Ventricles; Hemodynamics; Hydroxyproline; Myocardial Infarction; Procollagen-Proline Dioxygenase; Proline; Rats; Rats, Wistar; Recovery of Function; Stroke Volume; Ventricular Function, Left | 2001 |
Protection from pulmonary fibrosis in leukotriene-deficient mice.
Topics: Animals; Anti-Bacterial Agents; Arachidonate 5-Lipoxygenase; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Dinoprostone; Disease Models, Animal; Eicosanoids; Hydroxyproline; Leukotrienes; Lung; Mice; Mice, Knockout; Pulmonary Fibrosis | 2002 |
[Dynamic changes in dermal cell cycles, contents of hydroproline and ratios of collagen type I/III in the burned wound].
Topics: Animals; Burns; Cell Cycle; Collagen; Disease Models, Animal; Female; Hydroxyproline; Male; Rats; Rats, Sprague-Dawley; Wound Healing | 2000 |
Captopril inhibits the pulmonary toxicity of paraquat in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Combinations; Glutathione; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Lung; Male; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Polyunsaturated phosphatidylcholine lowers collagen deposition in a rat model of corrosive esophageal burn.
Topics: Animals; Burns, Chemical; Collagen; Disease Models, Animal; Esophageal Stenosis; Esophagus; Female; Hydroxyproline; Phosphatidylcholines; Rats | 2002 |
Dynamic pattern of IGF-I and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Collagen Type I; Disease Models, Animal; Female; Humans; Hydroxyproline; Insulin-Like Growth Factor I; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptides; Procollagen; Rats; Rats, Wistar | 2002 |
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers; Collagen; Coronary Vessels; Disease Models, Animal; Dogs; Echocardiography; Enalapril; Hydroxyproline; In Vitro Techniques; Myocardial Infarction; Myocardial Reperfusion; Transforming Growth Factor beta; Ventricular Remodeling | 2002 |
Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Bleomycin; Disease Models, Animal; Hydroxyproline; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Intubation, Intratracheal; Lung; Male; Microscopy, Confocal; Organ Size; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Specific Pathogen-Free Organisms | 2002 |
Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni.
Topics: Animals; Collagen; Disease Models, Animal; Granuloma; Hydroxyproline; Immunohistochemistry; Leptin; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Schistosoma mansoni; Schistosomiasis mansoni | 2002 |
CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, CD19; Antigens, Differentiation; B-Lymphocytes; Blotting, Western; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibrosis; Flow Cytometry; Humans; Hydroxyproline; Immunoglobulin M; Interleukin-6; Membrane Glycoproteins; Mice; NAD+ Nucleosidase; Phosphorylation; Precipitin Tests; Scleroderma, Systemic; Signal Transduction; Skin; Time Factors; Tyrosine; Up-Regulation | 2002 |
A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis.
Topics: Activating Transcription Factor 2; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Connective Tissue Growth Factor; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Gene Expression; Growth Inhibitors; Growth Substances; Hydroxyproline; Immediate-Early Proteins; In Situ Nick-End Labeling; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Lung; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Fibrosis; Pyrazoles; Pyridines; RNA, Messenger; Transcription Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Weight Gain | 2002 |
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; Lung; Paraquat; Procollagen-Proline Dioxygenase; Pulmonary Fibrosis; Rats; Subcellular Fractions; Thymidine | 1979 |
Evaluation of urinary alkaline ribonuclease activity in the assessment of subclinical malnutrition in weanling rats.
Topics: Animals; Clinical Enzyme Tests; Creatinine; Disease Models, Animal; Food; Hydrogen-Ion Concentration; Hydroxyproline; Male; Protein-Energy Malnutrition; Rats; Ribonucleases; Weaning | 1979 |
Alaskan malamute chondrodysplasia. II. Urinary excretion of hydroxyproline, uronic acid and acid mucopolysaccharides.
Topics: Animals; Disease Models, Animal; Dog Diseases; Dogs; Glycosaminoglycans; Hydroxyproline; Osteochondrodysplasias; Uronic Acids | 1976 |
The structural proteins of normal and diseased human myocardium.
Topics: Actomyosin; Adult; Aged; Animals; Cardiomegaly; Collagen; Coronary Disease; Disease Models, Animal; Humans; Hydroxyproline; Middle Aged; Myocardium; Swine | 1978 |
Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resportion.
Topics: Animals; Antigens; Bone Resorption; Calcium; Calcium, Dietary; Cattle; Cattle Diseases; Cyclic AMP; Disease Models, Animal; Etidronic Acid; Female; Homeostasis; Hydroxyproline; Hypocalcemia; Organophosphorus Compounds; Parathyroid Glands; Parathyroid Hormone; Phosphorus; Pregnancy; Puerperal Disorders; Thyroid Gland | 1976 |
Comparative study on the composition of the organic matrix of the long bones of the "normal" rat and of the mutant Op/Orl.
Topics: Amino Acids; Animals; Bone Matrix; Chondroitin Sulfates; Disease Models, Animal; Edetic Acid; Femur; Glycosaminoglycans; Hexosamines; Hexoses; Hyaluronic Acid; Hydroxyproline; Osteopetrosis; Proteins; Rats; Rats, Inbred Strains; Sex Factors; Tibia; Urea | 1977 |
An experimental model of hepatic fibrosis induced by the administration of dibutyltin dichloride.
Topics: Animals; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Liver; Male; Organotin Compounds; Proline; Rats; Time Factors | 1979 |
Pharmacological studies on experimental nephritic rats (3). Changes in the connective tissue components of renal cortex in the modified type of Masugi's nephritis.
Topics: Animals; Blood Proteins; Cholesterol; Disease Models, Animal; Hexosamines; Hydroxyproline; Kidney Cortex; Male; Nephritis; Proteinuria; Rats; Sialic Acids; Time Factors; Uronic Acids | 1978 |
The effect of uremia on wound tensile strength and collagen formation.
Topics: Animals; Body Weight; Collagen; Creatinine; Disease Models, Animal; Energy Intake; Hydroxyproline; Rats; Tensile Strength; Uremia; Wound Healing | 1977 |
Beta-aminopropionitrile as a radiation reaction preventive agent.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Lethal Dose 50; Male; Mice; Pulmonary Fibrosis; Radiation Injuries; Radiation-Protective Agents; Rats | 1976 |
[Study of urinary excretion of hydroxyproline in experimental silicosis].
Topics: Animals; Disease Models, Animal; Hydroxyproline; Male; Rats; Silicosis | 1976 |
Metabolic recovery of articular cartilage after intra-articular injections of glucocorticoid.
Topics: Animals; Cartilage Diseases; Cartilage, Articular; Collagen; Disease Models, Animal; DNA; Hexosamines; Hydrocortisone; Hydroxyproline; Injections, Intra-Articular; Knee Joint; Proteoglycans; Rabbits | 1976 |
The action of the benzopyrones on an experimental model of lymphoedema: a contribution to their mode of action.
Topics: Amino Acids; Animals; Benzopyrans; Blood Proteins; Disease Models, Animal; Female; Hydroxyproline; Lymphedema; Peptide Hydrolases; Peptides; Rats; Skin | 1976 |
[Chronic thioacetamide poisoning as a model for experimental liver cirrhosis].
Topics: Acetamides; Amino Acids; Animals; Collagen; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis; Rats; Thioacetamide | 1976 |
Biochemical confirmation of an experimental osteoarthritis model.
Topics: Acid Phosphatase; Animals; Cartilage, Articular; Disease Models, Animal; Femur; Glycine; Glycosaminoglycans; Hexosamines; Hydroxyproline; Knee Joint; Osteoarthritis; Protein Biosynthesis; Proteoglycans; Rabbits; Tritium | 1975 |
The carbon-tetrachloride-hepatotoxicity as a model of liver damage. First report: Long-time biochemical changes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Butyrylcholinesterase; Carbon Tetrachloride Poisoning; Collagen Diseases; Disease Models, Animal; Fatty Liver; Female; Hydroxyproline; Liver Diseases; Liver Function Tests; Necrosis; Rats; Sulfobromophthalein; Triglycerides | 1975 |
cis-hydroxyproline limits work necessary to flex a digit after tendon injury.
Topics: Animals; Biomechanical Phenomena; Cicatrix; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyproline; Male; Physical Exertion; Rats; Tendon Injuries; Tissue Adhesions; Wound Healing | 1975 |
Altered arterial connective tissue in racing greyhound dogs.
Topics: Animals; Arteries; Collagen; Disease Models, Animal; Dogs; Elastin; Hydroxyproline; Running | 1975 |
Development of a bleomycin hamster model of subchronic lung fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cricetinae; Disease Models, Animal; Hydroxyproline; Male; Mesocricetus; Procollagen-Proline Dioxygenase; Pulmonary Fibrosis; Trachea | 1992 |
[Comparative analysis of biological aggressiveness of dusts from different coal mines for determining the risk of development of pneumoconiosis among miners].
Topics: Air Pollutants, Occupational; Animals; Anthracosilicosis; Coal Mining; Disease Models, Animal; Dust; Humans; Hydroxyproline; Lung; Poland; Rats; Rats, Inbred Strains; Risk Factors; Silicon Dioxide | 1992 |
[Effect of tranilast, an anti-allergic drug, on the human keloid tissues].
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Histamine H1 Antagonists; Humans; Hydroxyproline; Keloid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; ortho-Aminobenzoates; Tissue Transplantation; Triamcinolone | 1992 |
[Effect of Z-103 on wound healing by dermal incision in guinea pigs].
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; Guinea Pigs; Hydroxyproline; Male; Neovascularization, Pathologic; Organometallic Compounds; Skin; Tensile Strength; Wound Healing; Zinc Compounds | 1992 |
Preliminary observations of chondral abrasion in a canine model.
Topics: Animals; Anterior Cruciate Ligament; Cartilage, Articular; Disease Models, Animal; Dogs; Femur; Hindlimb; Hydroxyproline; Osteoarthritis; Regeneration; Uronic Acids | 1992 |
Dependence of ultrasonic attenuation of liver on pathologic fat and fibrosis: examination with experimental fatty liver and liver fibrosis models.
Topics: Adipose Tissue; Animals; Body Water; Collagen; Disease Models, Animal; Fatty Liver; Hydroxyproline; Lipid Metabolism; Liver; Liver Cirrhosis, Experimental; Male; Rabbits; Ultrasonography | 1992 |
An experimental model of osteoarthrosis in the temporomandibular joint of the rabbit.
Topics: Animals; Bone Remodeling; Cartilage, Articular; Collagen; Disease Models, Animal; Fibroblasts; Glycosaminoglycans; Hydroxyproline; Male; Mandibular Condyle; Osteoarthritis; Rabbits; Temporomandibular Joint; Temporomandibular Joint Disorders | 1992 |
Pressure overload-induced cardiac hypertrophy with and without dilation.
Topics: Animals; Aorta; Biopsy; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Disease Models, Animal; Electrocardiography; Evaluation Studies as Topic; Guinea Pigs; Heart Failure; Heart Ventricles; Hemodynamics; Hydroxyproline; Liver; Lung; Male; Organ Size; Reproducibility of Results; Time Factors | 1992 |
Tamoxifen in the rat prevents estrogen-deficiency bone loss elicited with the LHRH agonist buserelin.
Topics: Animals; Body Weight; Bone Diseases, Metabolic; Bone Resorption; Buserelin; Calcium; Disease Models, Animal; Drug Interactions; Estradiol; Estrogens; Female; Gonadotropin-Releasing Hormone; Hydroxyproline; Organ Size; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1992 |
Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cadmium; Cadmium Chloride; Cell Count; Chlorides; Disease Models, Animal; Fibronectins; Hydroxyproline; Lung; Macrophages, Alveolar; Male; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Tumor Necrosis Factor-alpha | 1992 |
[Studies on the healing promoting action of Z-103 in chronic gastric ulcer models of rats].
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; DNA; Hydroxyproline; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing; Zinc; Zinc Compounds | 1992 |
Regulation of bone turnover and prevention of bone atrophy in ovariectomized beagle dogs by the administration of 24R,25(OH)2D3.
Topics: 24,25-Dihydroxyvitamin D 3; Animals; Bone and Bones; Bone Resorption; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Humans; Hydroxyproline; Ilium; Osteocalcin; Osteoclasts; Osteoporosis, Postmenopausal; Ovariectomy | 1992 |
[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].
Topics: Air Pollutants; Animals; Chemical Industry; Coke; Disease Models, Animal; Dust; Ferric Compounds; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Inbred Strains; Silicon Dioxide; Silicosis | 1991 |
[Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue].
Topics: Air Pollutants, Occupational; Animals; Anthracosilicosis; Coal Mining; Disease Models, Animal; Dust; Hydroxyproline; Lung; Male; Poland; Pulmonary Fibrosis; Rats; Rats, Inbred Strains; Silicon Dioxide | 1991 |
[Effect of selenium on the connective tissue metabolism in rats].
Topics: Animals; Chronic Disease; Connective Tissue; Disease Models, Animal; Glycosaminoglycans; Hydroxyproline; Male; Rats; Rats, Inbred Strains; Selenium; Sodium Selenite; Time Factors; Water Pollutants, Chemical | 1991 |
The blotchy mouse, lung desmosine, and emphysema.
Topics: Animals; Desmosine; Disease Models, Animal; Hydroxyproline; Lung; Mice; Protein-Lysine 6-Oxidase; Pulmonary Emphysema | 1991 |
The influence of a histamine2-receptor antagonist on the healing of an experimentally induced gastric mucosal lesion.
Topics: Animals; Cell Division; Disease Models, Animal; DNA; Gastric Mucosa; Histamine H2 Antagonists; Hydroxyproline; Male; Ranitidine; Rats; Rats, Inbred Strains; RNA; Stomach Diseases; Wound Healing | 1990 |
Chronic administration of ethanol with high vitamin A supplementation in a liquid diet to rats does not cause liver fibrosis. 1. Morphological observations.
Topics: Animals; Biopsy; Diet; Disease Models, Animal; Ethanol; Hydroxyproline; Liver Cirrhosis, Alcoholic; Male; Microscopy, Electron; Rats; Rats, Inbred BN; Rats, Inbred Strains; Vitamin A | 1991 |
[Effect of chronic mercuric chloride poisoning on the levels of connective tissue metabolites in the urine and blood of rats].
Topics: Animals; Chronic Disease; Connective Tissue; Disease Models, Animal; Glycosaminoglycans; Hydroxyproline; Male; Mercuric Chloride; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1991 |
[Evaluation of the effect of the detergent Rokafenol N-8 on the development and course of experimental pneumoconiosis caused by coal mine dust].
Topics: Administration, Inhalation; Animals; Anthracosilicosis; Coal; Coal Mining; Detergents; Disease Models, Animal; Dust; Hydroxyproline; Lung; Rats; Stimulation, Chemical | 1991 |
[Basal studies on the model of circular excisional wounds made on the dorsal skin of rats treated with hydrocortisone].
Topics: Animals; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrocortisone; Hydroxyproline; Male; Rats; Rats, Inbred Strains; Wound Healing; Wounds and Injuries; Zinc Oxide | 1991 |
Excretion of urinary hydroxyproline in correlation with severity of induced osteomyelitis in rabbits.
Topics: Animals; Body Weight; Collagen; Disease Models, Animal; Hemodynamics; Hydroxyproline; Osteomyelitis; Rabbits; Staphylococcal Infections | 1991 |
Short term functional effects of bladder outlet obstruction in the cat.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Cats; Disease Models, Animal; Female; Hydroxyproline; In Vitro Techniques; Phosphocreatine; Rabbits; Receptors, Muscarinic; Time Factors; Urinary Bladder; Urinary Bladder Neck Obstruction | 1990 |
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Asbestosis; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Hydroxyproline; Lung; Male; Polyethylene Glycols; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Superoxide Dismutase | 1990 |
EGF increases short-term type I collagen accumulation during wound healing in diabetic rats.
Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Endopeptidases; Epidermal Growth Factor; Hydroxyproline; Male; Microbial Collagenase; Proteins; Rats; Rats, Inbred Strains; Time Factors; Wound Healing | 1990 |
The effects of testosterone propionate and methenolone enanthate on the healing of humeral osteotomies in the Wistar rat.
Topics: Animals; Bony Callus; Calcium; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclinical; Female; Fractures, Bone; Hexosamines; Humerus; Hydroxyproline; Methenolone; Osteotomy; Prospective Studies; Random Allocation; Rats; Rats, Inbred Strains; Stress, Mechanical; Testosterone; Wound Healing | 1990 |
The effect of perfluorochemical fluosol-DA (20%) on myocardial infarct healing in the rabbit.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Combinations; Fluorocarbons; Foam Cells; Heart Ventricles; Hydroxyethyl Starch Derivatives; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Rabbits; Random Allocation; Tissue Distribution | 1990 |
Trabecular bone remodeling and bone mineral density in the adult cat during chronic dietary acidification with ammonium chloride.
Topics: Acidosis; Ammonium Chloride; Animal Feed; Animals; Biopsy; Bone Density; Bone Development; Bone Resorption; Cats; Disease Models, Animal; Female; Hydroxyproline; Male; Time Factors; Tomography, X-Ray Computed | 1990 |
Morphometric studies on wound healing after systemic administration of adriamycin and local application of fibrin sealant. Application of a new wound healing model using spongiosa implants.
Topics: Animals; Aprotinin; Disease Models, Animal; DNA; Doxorubicin; Drug Combinations; Factor XIII; Fibrin Tissue Adhesive; Fibrinogen; Granulation Tissue; Hydroxyproline; Male; Rats; Rats, Inbred Strains; Thrombin; Wound Healing | 1986 |
Protein metabolism and fibrosis in experimental canine obstructive lymphedema.
Topics: alpha-Macroglobulins; Animals; Collagen; Disease Models, Animal; Dogs; Extracellular Space; Fibrosis; Hydroxyproline; Lymph; Lymphatic System; Lymphedema; Microbial Collagenase; Peptide Hydrolases; Proteins; Skin | 1987 |
High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Female; Hydroxyproline; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pulmonary Fibrosis; Species Specificity | 1987 |
Ameliorating effect of an interferon inducer polyinosinic-polycytidylic acid on bleomycin-induced lung fibrosis in hamsters. Morphologic and biochemical evidence.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Disease Models, Animal; Hydroxyproline; Lung; Male; Mesocricetus; Microscopy, Electron; Poly I-C; Procollagen-Proline Dioxygenase; Proteins; Pulmonary Fibrosis | 1988 |
Collagen breakdown during acute lung injury.
Topics: Acute Disease; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Endothelium; Hydroxyproline; Hypoxia; Lung; Lung Injury; Male; Mice; Mice, Inbred Strains | 1988 |
Wound healing in nude mice: a study on the regulatory role of lymphocytes in fibroplasia.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Evaluation Studies as Topic; Hydroxyproline; Hypersensitivity, Delayed; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Skin; T-Lymphocytes; Tensile Strength; Thymus Gland; Time Factors; Wound Healing | 1989 |
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Histocytochemistry; Hydroxyproline; Lung; Male; Mesocricetus; Pulmonary Fibrosis; Tissue Distribution | 1989 |
Therapeutic treatment of canine osteoarthritis with glycosaminoglycan polysulfuric acid ester.
Topics: Animals; Cartilage, Articular; Disease Models, Animal; Dogs; Glycosaminoglycans; Hydroxyproline; Metalloendopeptidases; Osteoarthritis; Proteoglycans; Serine Endopeptidases; Uronic Acids | 1989 |
The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Body Weight; Collagen; Deficiency Diseases; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Peptide Fragments; Predictive Value of Tests; Procollagen; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Thioacetamide-induced cirrhosis-like liver lesions in rats--usefulness and reliability of this animal model.
Topics: Acetamides; Acetylglucosaminidase; Animals; Disease Models, Animal; Female; Hydroxyproline; Liver; Liver Cirrhosis; Microbial Collagenase; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors | 1988 |
The role of neutrophils in the development of cadmium chloride-induced emphysema in lathyrogen-fed hamsters.
Topics: Aminopropionitrile; Amitrole; Animals; Cadmium; Cadmium Chloride; Cricetinae; Disease Models, Animal; Epinephrine; Female; Hydroxyproline; Lung; Malondialdehyde; Mesocricetus; Microbial Collagenase; Neutrophils; Pancreatic Elastase; Pulmonary Emphysema | 1985 |
Humoral hypercalcemia of malignancy in nude mouse model of a canine adenocarcinoma derived from apocrine glands of the anal sac. Biochemical, histomorphometric, and ultrastructural studies.
Topics: Adenocarcinoma; Anal Gland Neoplasms; Anal Sacs; Animals; Apocrine Glands; Calcitriol; Calcium; Cyclic AMP; Cytoplasmic Granules; Disease Models, Animal; Dogs; Female; Hydroxyproline; Hypercalcemia; Lumbar Vertebrae; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Parathyroid Glands; Phosphorus; Sweat Glands; Thyroid Gland | 1986 |
A biochemical method for the quantitation of myocardial scarring after experimental coronary artery occlusion.
Topics: Animals; Arteries; Chloramines; Collagen; Coronary Vessels; Disease Models, Animal; Heart Ventricles; Hydrogen-Ion Concentration; Hydroxyproline; Ligation; Male; Myocardial Infarction; Nitroglycerin; Rats; Rats, Inbred Strains; Tosyl Compounds | 1986 |
The efficacy of subcutaneous goretex implants in monitoring wound healing response in experimental protein deficiency.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Methods; Nutritional Status; Prostheses and Implants; Protein Deficiency; Rats; Rats, Inbred Strains; Wound Healing | 1988 |
Late functional, biochemical and histological changes in the rat lung after fractionated irradiation to the whole thorax.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Hydroxyproline; Lung; Radiotherapy; Rats; Rats, Inbred Strains; Respiratory Function Tests | 1987 |
Pulmonary interstitial fibrosis induced in hapten-immune hamsters.
Topics: Animals; Collagen; Cricetinae; Dermatitis, Contact; Disease Models, Animal; Haptens; Histocytochemistry; Hydroxyproline; Immunization; Lung; Picrates; Pulmonary Fibrosis; Skin; Time Factors | 1987 |
Collagenous abnormalities in the heart of the tight-skin mouse.
Topics: Animals; Collagen; Creatine Kinase; Disease Models, Animal; Hexosamines; Hydroxyproline; Mice; Mice, Mutant Strains; Microscopy, Electron; Myocardium; Scleroderma, Systemic | 1987 |
In vivo collagen metabolism in spontaneously diabetic (db/db) mice.
Topics: Animals; Collagen; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydroxyproline; Mice; Mice, Mutant Strains; Mice, Obese; Tissue Distribution | 1986 |
[Participation of autoimmune and autoaggressive reactions in the mechanism of connective tissue disorganization].
Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Cattle; Collagen Diseases; Disease Models, Animal; DNA; Fluorescent Antibody Technique; Hyaluronic Acid; Hydroxyproline; Immunization, Passive; Lupus Erythematosus, Systemic; Methods; Neutrophils; Organ Specificity; Rabbits; Rats; Species Specificity; Spleen | 1970 |
Nephrotoxic serum nephritis. I. Chemical, morphologic, and functional changes in the glomerular basement membrane during the evolution of nephritis.
Topics: Animals; Antigen-Antibody Reactions; Basement Membrane; Capillaries; Centrifugation; Disease Models, Animal; DNA; Female; Fluorescent Antibody Technique; gamma-Globulins; Glomerulonephritis; Hexosamines; Hydroxyproline; Immune Sera; Male; Mice; Microscopy, Electron; Microscopy, Fluorescence; Nephrotic Syndrome; Phospholipids; Proteinuria; Rats; Staining and Labeling; Vibration | 1970 |
The role of infection on wound healing.
Topics: Abdomen; Abscess; Animals; Collagen; Disease Models, Animal; Female; Hydroxyproline; Peritoneum; Protein Deficiency; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Sepsis; Stomach; Stress, Mechanical; Surgical Wound Infection; Turpentine; Wound Healing | 1974 |
Mechanical properties of rat cardiac muscle during experimental hypertrophy.
Topics: Animals; Aorta, Thoracic; Cardiomegaly; Constriction; Disease Models, Animal; Elasticity; Heart; Hydroxyproline; Hypoxia; L-Lactate Dehydrogenase; Muscle Contraction; Myocardium; Organ Size; Proteins; Rats | 1971 |
Synthesis of collagen, myosin, noncollagenous protein, and DNA during experimental myocardial hypertrophy in the rat.
Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; DNA Replication; Hydroxyproline; Muscle Proteins; Myocardium; Myosins; Protein Biosynthesis; Rats | 1972 |
Histamine metabolism in experimental silicosis. II. In vivo experiments in guinea pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Collagen; Disease Models, Animal; Guinea Pigs; Histamine; Histidine; Hydroxyproline; Lung; Male; Silicon Dioxide; Silicosis | 1971 |
Experimental silicosis of the rat. Correlation of functional, biochemical, and histological changes.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Hematocrit; Hemoglobinometry; Hydroxyproline; Lung; Lung Compliance; Male; Organ Size; Rats; Respiratory Function Tests; Silicon Dioxide; Silicosis; Ventilation-Perfusion Ratio | 1971 |
Debridement of experimental skin burns of pigs with bromelain, a pineapple-stem enzyme.
Topics: Animals; Anti-Bacterial Agents; Bromelains; Burns; Debridement; Disease Models, Animal; Dogs; Drug Synergism; Hydroxyproline; In Vitro Techniques; Microbial Collagenase; Ointments; Rats; Skin; Skin Transplantation; Sulfonamides; Swine; Time Factors; Tosyl Compounds; Transplantation, Autologous | 1973 |
Effect of experimental chronic renal insufficiency on bone mineral and collagen maturation.
Topics: Animals; Bone and Bones; Bone Development; Bone Matrix; Calcium; Calcium Isotopes; Carbonates; Centrifugation, Density Gradient; Collagen; Disease Models, Animal; Female; Hydrogen-Ion Concentration; Hydroxycholecalciferols; Hydroxyproline; Kidney Failure, Chronic; Phosphates; Rats; Rats, Inbred Strains; Time Factors; Tritium; Vitamin D; X-Ray Diffraction | 1972 |
Heparin osteoporosis. An experimental model using rats.
Topics: Animals; Biomechanical Phenomena; Bone and Bones; Collagen; Disease Models, Animal; Female; Fibroblasts; Heparin; Humerus; Hydroxyproline; Hypersensitivity; Injections, Subcutaneous; Leukopenia; Microradiography; Mitosis; Osteoporosis; Proline; Radius; Rats; Tritium; Ulna; Wound Healing | 1973 |
[Heparin-induced osteopathy in animal experiments--a model for osteoporosis? Influence of heparin on the concentrations of hydroxyapatite, citrate, and hydroxyproline in the bones of rats of various ages. I].
Topics: Animals; Bone and Bones; Citrates; Disease Models, Animal; Heparin; Hydroxyapatites; Hydroxyproline; Male; Osteoporosis; Rats | 1973 |
[Experimental oxalic lithiases in rats. Influence of certain Krebs cycle intermediates].
Topics: Administration, Oral; Animals; Citrates; Citric Acid Cycle; Disease Models, Animal; Ethylene Glycols; Glyoxylates; Hydroxyproline; Injections, Intraperitoneal; Kidney Calculi; Malates; Oxalates; Oxaloacetates; Rats; Succinates | 1973 |
The effects of azathioprine on CCl4 induced cirrhosis in the rat.
Topics: Adenosine Triphosphate; Animals; Azathioprine; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disease Models, Animal; DNA; Female; Hydroxyproline; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Organ Size; Proteins; Rats; RNA; Triglycerides | 1974 |
Metabolic and circulatory contributions to oxygen gradients in wounds.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Collagen; Disease Models, Animal; Hydroxyproline; Male; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Polyethylenes; Rabbits; Wound Healing | 1972 |
Inhibition of scar formation by the proline analog cis-hydroxyproline.
Topics: Animals; Cicatrix; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Postoperative Complications; Rats; Tendon Injuries; Tendons | 1972 |
Healing of colonic anastomoses following resection for experimental "diverticulitis".
Topics: Animals; Collagen; Colon; Colostomy; Disease Models, Animal; Diverticulitis, Colonic; Dogs; Feces; Female; Granulation Tissue; Hydroxyproline; Male; Wound Healing | 1971 |
Biochemical changes in non-infarcted heart muscle following myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biopsy; Carbon Isotopes; Coronary Vessels; Disease Models, Animal; Dogs; Heart Ventricles; Hemodynamics; Hydroxyproline; Lactates; Ligation; Myocardial Infarction; Myocardium; Norepinephrine; Oxygen Consumption; Phosphocreatine; Pyruvates; Time Factors; Water | 1971 |
Protocollagen proline hydroxylase activity in experimental pulmonary fibrosis of rats.
Topics: Animals; Ascorbic Acid; Collagen; Disease Models, Animal; Hydroxyproline; Iron; Ketoglutaric Acids; Mixed Function Oxygenases; Proline; Pulmonary Fibrosis; Rats; Silicosis | 1970 |