hydroxyproline has been researched along with Disease, Pulmonary in 53 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The data presented here demonstrate that BALB/c, ICR and C57BL/6NHsd mice, with LD50s of 1739, 1243 and 917 respectively, exhibit similar time courses of repair (as assessed by the incorporation of radiolabelled thymidine into DNA) and pulmonary fibrosis (as assessed by lung hydroxyproline content) when given a single 400 mg/kg dose of BHT." | 3.68 | Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene. ( DiGiovanni, J; Kehrer, JP, 1990) |
| " Reduced tissue VEGF bioavailability has previously been demonstrated with this model." | 1.43 | Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. ( Driscoll, B; Grikscheit, TC; Hiatt, MJ; Hou, X; Lee, J; Levin, DE; Lundin, A; Mojica, SG; Navarro, S; Reddy, R; Spurrier, RG; Wieck, MM, 2016) |
| "Berberine treatments were either provided in preventive or therapeutic mode respectively." | 1.39 | Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study. ( Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G, 2013) |
| "In BALB/c mice, as in man, progressive pulmonary tuberculosis is accompanied by increasing expression of IL-4." | 1.32 | Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. ( Aguilar, D; Hernandez, ML; Hernandez-Pando, R; Orozco, H; Rook, G, 2004) |
| "Treatment with taurine and niacin attenuated the BL-induced increases in proinflammatory cytokines such as IL-1alpha, TNF-alpha, IL-6, and TGF-beta in BALF and lung hydroxyproline content of the mice in BL + TN groups." | 1.31 | Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Based on the doses that killed 50% of the animals (LD50s), the various components were found to be 10 to 1250 times more toxic when given intratracheally than when given orally (according to reported oral LD50s in rats)." | 1.30 | Pulmonary toxicity of components of textile paint linked to the Ardystil syndrome: intratracheal administration in hamsters. ( Clottens, FL; Demedts, M; Nemery, B; Verbeken, EK, 1997) |
| "Since pulmonary fibrosis develops even in nude athymic mice, T cells do not seem to play a primary part in fibrogenic response but they regulate, at least to some extent, the response of inflammatory cells and fibrogenesis of the lung." | 1.29 | T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice. ( Horiuchi, T; Ito, K; Kuwabara, M; Ohta, K; Shiga, J; Suzuki, N; Takizawa, H; Ueda, T, 1996) |
| "Lung hydroxyproline content was measured as an index of interstitial fibrosis." | 1.28 | Monocrotaline-induced cardiopulmonary injury in rats. Modification by the neutrophil elastase inhibitor SC39026. ( Hinz, JM; Molteni, A; Ts'ao, CH; Ward, WF, 1989) |
| "A severe interstitial pneumonitis was evident histologically 15 days after BHT-treatment." | 1.27 | Enhanced acute lung damage following corticosteroid treatment. ( Kehrer, JP; Klein-Szanto, AJ; Pearlman, R; Rosner, MH; Sorensen, EM, 1984) |
| "Hydroxyproline production was a linear function of time for up to 90 minutes in vivo and three hours in vitro." | 1.27 | Comparison of in vitro and in vivo rates of collagen synthesis in normal and damaged lung tissue. ( Kehrer, JP; Lee, YC; Solem, SM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (54.72) | 18.7374 |
| 1990's | 12 (22.64) | 18.2507 |
| 2000's | 10 (18.87) | 29.6817 |
| 2010's | 2 (3.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chitra, P | 1 |
| Saiprasad, G | 1 |
| Manikandan, R | 1 |
| Sudhandiran, G | 1 |
| Wieck, MM | 1 |
| Spurrier, RG | 1 |
| Levin, DE | 1 |
| Mojica, SG | 1 |
| Hiatt, MJ | 1 |
| Reddy, R | 1 |
| Hou, X | 1 |
| Navarro, S | 1 |
| Lee, J | 1 |
| Lundin, A | 1 |
| Driscoll, B | 1 |
| Grikscheit, TC | 1 |
| Güler, G | 1 |
| Türközer, Z | 1 |
| Ozgur, E | 1 |
| Seyhan, N | 1 |
| Tsai, SF | 1 |
| Liu, BL | 1 |
| Liao, JW | 1 |
| Wang, JS | 1 |
| Hwang, JS | 1 |
| Wang, SC | 1 |
| Tzeng, YM | 1 |
| Ho, SP | 1 |
| SALTZMAN, HA | 1 |
| SIEKER, HO | 1 |
| GREEN, J | 1 |
| VYSKOCIL, J | 1 |
| DLUHOS, M | 1 |
| Fattman, CL | 2 |
| Chang, LY | 1 |
| Termin, TA | 1 |
| Petersen, L | 1 |
| Enghild, JJ | 1 |
| Oury, TD | 2 |
| Hernandez-Pando, R | 1 |
| Aguilar, D | 1 |
| Hernandez, ML | 1 |
| Orozco, H | 1 |
| Rook, G | 1 |
| Tan, RJ | 1 |
| Tobolewski, JM | 1 |
| Mohammadi-Karakani, A | 1 |
| Ghazi-Khansari, M | 1 |
| Sotoudeh, M | 1 |
| Yoshimura, S | 1 |
| Nishimura, Y | 1 |
| Nishiuma, T | 1 |
| Yamashita, T | 1 |
| Kobayashi, K | 1 |
| Yokoyama, M | 1 |
| Kaneko, Y | 1 |
| Takashima, K | 1 |
| Suzuki, N | 2 |
| Yamana, K | 1 |
| George, PM | 1 |
| Vissers, MC | 1 |
| Travis, J | 1 |
| Winterbourn, CC | 1 |
| Carrell, RW | 1 |
| Tom, WM | 1 |
| Montgomery, MR | 1 |
| Lafranconi, WM | 1 |
| Duhamel, RC | 1 |
| Brendel, K | 1 |
| Huxtable, RJ | 1 |
| Kehrer, JP | 4 |
| Klein-Szanto, AJ | 1 |
| Sorensen, EM | 1 |
| Pearlman, R | 1 |
| Rosner, MH | 1 |
| Romatowska-Dziub, A | 1 |
| Krutul, L | 1 |
| Kowal, E | 1 |
| Boros, DL | 1 |
| Lande, MA | 1 |
| Carrick, L | 1 |
| O'Brien-Ladner, AR | 1 |
| Wesselius, LJ | 1 |
| Stechschulte, DJ | 1 |
| Smith, RE | 1 |
| Strieter, RM | 1 |
| Phan, SH | 1 |
| Lukacs, NW | 1 |
| Huffnagle, GB | 1 |
| Wilke, CA | 1 |
| Burdick, MD | 1 |
| Lincoln, P | 1 |
| Evanoff, H | 1 |
| Kunkel, SL | 1 |
| Denis, M | 1 |
| Bisson, D | 1 |
| Kodavanti, UP | 1 |
| Hatch, GE | 1 |
| Starcher, B | 1 |
| Giri, SN | 2 |
| Winsett, D | 1 |
| Costa, DL | 1 |
| Blazka, ME | 1 |
| Dixon, D | 1 |
| Haskins, E | 1 |
| Rosenthal, GJ | 1 |
| Ohta, K | 1 |
| Horiuchi, T | 1 |
| Takizawa, H | 1 |
| Ueda, T | 1 |
| Kuwabara, M | 1 |
| Shiga, J | 1 |
| Ito, K | 1 |
| Clottens, FL | 1 |
| Verbeken, EK | 1 |
| Demedts, M | 1 |
| Nemery, B | 1 |
| Gurujeyalakshmi, G | 1 |
| Wang, Y | 1 |
| van Bree, L | 1 |
| Dormans, JA | 1 |
| Boere, AJ | 1 |
| Rombout, PJ | 1 |
| Loxley, R | 1 |
| Pawelec, D | 2 |
| Jakubowska, L | 1 |
| Szaflarska-Stojko, E | 2 |
| Olczyk, D | 1 |
| Domagała, B | 1 |
| Stojko, J | 1 |
| Ociepiński, M | 1 |
| Grant, MM | 1 |
| Burnett, CM | 1 |
| Fein, AM | 1 |
| Kaminskaia, GO | 1 |
| Puriaeva, NL | 1 |
| Stepanian, IE | 1 |
| DiGiovanni, J | 1 |
| Bigby, TD | 1 |
| Allen, D | 1 |
| Leslie, CG | 1 |
| Henson, PM | 1 |
| Cherniack, RM | 1 |
| Molteni, A | 1 |
| Ward, WF | 1 |
| Ts'ao, CH | 1 |
| Hinz, JM | 1 |
| Lindenschmidt, RC | 1 |
| Witschi, HP | 2 |
| Masiak, M | 1 |
| Podwysocki, B | 1 |
| Gajewska, A | 1 |
| Tron, V | 1 |
| Wright, JL | 1 |
| Harrison, N | 1 |
| Wiggs, B | 1 |
| Churg, A | 1 |
| Bowers, RR | 1 |
| Birch, ML | 1 |
| Thomas, DW | 1 |
| Durham, SK | 1 |
| Mezza, LE | 1 |
| Imamura, T | 1 |
| Durr, RA | 1 |
| Dubaybo, BA | 1 |
| Thet, LA | 1 |
| Lee, YC | 1 |
| Solem, SM | 1 |
| Martin, FM | 1 |
| Lorenzen, I | 1 |
| Hansen, LK | 1 |
| Kaiser, E | 1 |
| Klujber, L | 1 |
| Sulyok, E | 1 |
| Brocard, H | 1 |
| Akoun, G | 1 |
| Bruhat, M | 1 |
| Bayard, D | 1 |
| Niinikoski, J | 1 |
| Nikkari, T | 1 |
| Kulonen, E | 1 |
| Emmrich, R | 1 |
| Häntzschel, HJ | 1 |
| Häntzschel, H | 1 |
| Wusteman, FS | 1 |
| Johnson, DB | 1 |
| Dodgson, KS | 1 |
| Rosenkrantz, H | 1 |
| Esber, HJ | 1 |
| Sprague, R | 1 |
53 other studies available for hydroxyproline and Disease, Pulmonary
| Article | Year |
|---|---|
Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study.
Topics: Animals; Antimetabolites; Berberine; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Col | 2013 |
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease.
Topics: Animals; Apoptosis; Body Weight; Collagen; Female; Gene Expression Regulation; Hydroxyproline; Linea | 2016 |
Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline.
Topics: Acetylcysteine; Animals; Antioxidants; Biodiversity; Catechin; Electromagnetic Fields; Guinea Pigs; | 2009 |
Pulmonary toxicity of thuringiensin administered intratracheally in Sprague-Dawley rats.
Topics: Adenosine; Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Fibronec | 2003 |
Hexosamine and hydroxyproline content in human bronchial cartilage from aged and diseased lungs.
Topics: Bronchi; Cartilage; Glucosamine; Hexosamines; Humans; Hydroxyproline; Lung; Lung Diseases; Pulmonary | 1963 |
[EFFECT OF ACUTE INFLAMMATION ON THE DISTRIBUTION AND ELIMINATION OF QUARTZ DUST FROM RABBIT LUNGS. EXPERIMENTAL STUDY ON ELIMINATION OF DUST FROM THE LUNGS. III].
Topics: Animals; Bronchitis; Dust; Hexosamines; Hydroxyproline; Inflammation; Lung; Lung Diseases; Pneumocon | 1963 |
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Extracell | 2003 |
Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.
Topics: Animals; Granuloma; Hydroxyproline; Hypersensitivity, Delayed; Inflammation; Interferon-gamma; Inter | 2004 |
Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase.
Topics: Animals; Asbestos, Crocidolite; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lu | 2006 |
Lisinopril ameliorates paraquat-induced lung fibrosis.
Topics: Animals; Hydroxyproline; Lipid Peroxidation; Lisinopril; Lung Diseases; Male; Paraquat; Rats; Rats, | 2006 |
Overexpression of nitric oxide synthase by the endothelium attenuates bleomycin-induced lung fibrosis and impairs MMP-9/TIMP-1 balance.
Topics: Animals; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Endothelium, Vascular; Fibrosis | 2006 |
Effects of theophylline on chronic inflammatory lung injury induced by LPS exposure in guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Cell Movement; Chron | 2007 |
A genetically engineered mutant of alpha 1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease.
Topics: alpha 1-Antitrypsin; Basement Membrane; Connective Tissue; Genetic Engineering; Humans; Hydroxyproli | 1984 |
Biochemical and morphological assessments of bleomycin pulmonary toxicity in rats.
Topics: Animals; Bleomycin; Body Weight; Hydroxyproline; Lung Diseases; Male; Microsomes; Organ Size; Procol | 1980 |
Differentiation of the cardiac and pulmonary toxicity of monocrotaline, a pyrrolizidine alkaloid.
Topics: Animals; Cardiomegaly; Collagen; DNA; Female; Hydroxyproline; Lipid Metabolism; Lung Diseases; Male; | 1984 |
Enhanced acute lung damage following corticosteroid treatment.
Topics: Acute Disease; Animals; Butylated Hydroxytoluene; DNA; Hydroxyproline; Lung; Lung Diseases; Male; Me | 1984 |
[Clinical usefulness of determining urinary hydroxyproline in various lung diseases].
Topics: Adult; Aged; Circadian Rhythm; Humans; Hydroxyproline; Lung Diseases; Middle Aged | 1983 |
Collagen production rates following acute lung damage induced by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; Collagen; Female; Hydroxyproline; Kinetics; Lung Diseases; Mice; | 1982 |
The artificial granuloma. III. Collagen synthesis during the cell-mediated granulomatous response as determined in explanted granulomas.
Topics: Animals; Antigens; Collagen; Female; Granuloma; Hydroxyproline; Immunity, Cellular; Inflammation; Lu | 1981 |
Bleomycin injury of the lung in a mast-cell-deficient model.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Histamine Release; Hydroxyproline; Lung; Lung Dise | 1993 |
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL4; Cytokines; Enzyme-Linked Immunosor | 1994 |
Antigen-induced alveolitis: cytokine production in a mouse model.
Topics: Alveolitis, Extrinsic Allergic; Animals; Antigens; Bronchoalveolar Lavage Fluid; Cytokines; Erythroc | 1995 |
Ozone-induced pulmonary functional, pathological, and biochemical changes in normal and vitamin C-deficient guinea pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Collagen; Desmosine; Elastin; Female; | 1995 |
Pulmonary toxicity to intratracheally administered indium trichloride in Fischer 344 rats.
Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Female; Fibronectins; Hydroxyproline; Indium; In | 1994 |
T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lung Diseases; Male; Mice | 1996 |
Pulmonary toxicity of components of textile paint linked to the Ardystil syndrome: intratracheal administration in hamsters.
Topics: Acetylglucosaminidase; Administration, Inhalation; Alkaline Phosphatase; Animals; Body Weight; Bronc | 1997 |
Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Down-Reg | 2000 |
Time study on development and repair of lung injury following ozone exposure in rats.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Cell Differentiation; DNA; Hydroxyproline; Leukocyt | 2001 |
Effect of iron on the determination of proline and hydroxyproline in formalin-fixed coalworkers' lungs.
Topics: Coal Mining; Formaldehyde; Histocytochemistry; Humans; Hydroxyproline; Iron; Lung; Lung Diseases; Pr | 1978 |
[Hydroxyproline and lung diseases].
Topics: Collagen; Connective Tissue; Humans; Hydroxyproline; Lung; Lung Diseases; Lung Neoplasms; Neoplasm M | 1975 |
[Biological evaluation of experiments in rats of Australian and Italian talc aggressiveness].
Topics: Animals; Hydroxyproline; Lung; Lung Diseases; Male; Rats; Rats, Wistar; Talc | 1992 |
[Evaluation of fibrotic effects from dusts originating from KWK "Brzeszcze" on lung tissue].
Topics: Animals; Dust; Emphysema; Hemolysis; Hydroxyproline; Injections, Intraperitoneal; Lung; Lung Disease | 1992 |
Effect of prostaglandin E1 infusion on leukocyte traffic and fibrosis in acute lung injury induced by bleomycin in hamsters.
Topics: Acute Disease; Alprostadil; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Movem | 1991 |
[The interrelation of collagen metabolism and fibrosis formation in patients with disseminated processes of the lungs].
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Collagen; Female; Humans; Hydroxyproline; Lung Diseases | 1990 |
Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; DNA; Female; Hydroxyproline; Lethal Dose 50; Lung; Lung Diseases; | 1990 |
Bleomycin-induced lung injury in the rabbit. Analysis and correlation of bronchoalveolar lavage, morphometrics, and fibroblast stimulating activity.
Topics: Animals; Bleomycin; Bronchi; Fibroblasts; Hydroxyproline; Lung; Lung Diseases; Male; Pulmonary Alveo | 1985 |
Monocrotaline-induced cardiopulmonary injury in rats. Modification by the neutrophil elastase inhibitor SC39026.
Topics: Animals; Cardiomegaly; Chlorobenzoates; Epoprostenol; Hydroxyproline; Lung Diseases; Male; Monocrota | 1989 |
Propranolol-induced elevation of pulmonary collagen.
Topics: Animals; Bleomycin; Butylated Hydroxytoluene; Collagen; Cyclic AMP; Cyclic GMP; Fibroblasts; Hydroxy | 1985 |
Behaviour of angiotensin converting enzyme, hydroxyproline and some protease inhibitors in pulmonary sarcoidosis.
Topics: Humans; Hydroxyproline; Lung Diseases; Peptidyl-Dipeptidase A; Protease Inhibitors; Sarcoidosis | 1988 |
Cigarette smoke makes airway and early parenchymal asbestos-induced lung disease worse in the guinea pig.
Topics: Animals; Asbestos; Asbestos, Amosite; Female; Guinea Pigs; Hydroxyproline; Lung; Lung Diseases; Nico | 1987 |
A biochemical study of the carrageenan-induced granuloma in the rat lung.
Topics: Acetylglucosaminidase; Animals; Carrageenan; Cathepsin B; Cathepsins; Collagen; Granuloma; Hydroxypr | 1985 |
Pulmonary endothelial and alveolar epithelial lesions induced by O,O,S-trimethyl phosphorothioate in rats.
Topics: Animals; Body Weight; Endothelium, Vascular; Female; Hydroxyproline; Lung; Lung Diseases; Microscopy | 1988 |
Repair of chronic hyperoxic lung injury: changes in lung ultrastructure and matrix.
Topics: Animals; Cell Count; Connective Tissue; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Ex | 1987 |
Comparison of in vitro and in vivo rates of collagen synthesis in normal and damaged lung tissue.
Topics: Animals; Butylated Hydroxytoluene; Collagen; Hydroxyproline; In Vitro Techniques; Lung; Lung Disease | 1986 |
Cadmium-induced lung injury: cell kinetics and long-term effects.
Topics: Aerosols; Animals; Atmosphere Exposure Chambers; Autoradiography; Bronchi; Cadmium; Cadmium Chloride | 1985 |
Effect of glucocorticoids on human vascular connective tissue. Biochemical and microscopic studies of vein biopsies.
Topics: Adult; Aged; Connective Tissue; Female; Glycosaminoglycans; Hepatitis; Hexosamines; Histocytochemist | 1967 |
New biochemical aspect of idiopathic pulmonary haemosiderosis in infancy.
Topics: Collagen; Female; Glycosaminoglycans; Hemosiderosis; Humans; Hyaluronic Acid; Hydroxyproline; Infant | 1970 |
[Urinary excretion of 5-hydroxyproline in lung cancer].
Topics: Female; Humans; Hydroxyproline; Lung Diseases; Lung Neoplasms; Male | 1968 |
[Urinary hydroxyproline in some non-specific lung diseases].
Topics: Adult; Aged; Collagen; Female; Humans; Hydroxyproline; Lung Diseases; Lung Neoplasms; Male; Middle A | 1972 |
Pulmonary oxygen toxicity: composition of endobronchial saline extracts of rats during exposure to oxygen.
Topics: Animals; Atmospheric Pressure; Bronchi; Capillary Permeability; Centrifugation; Chromatography, Thin | 1971 |
[The clinical significance of hydroxyproline in the urine].
Topics: Adenoma; Adenoma, Chromophobe; Adolescent; Adult; Age Factors; Aged; Arteriosclerosis; Arthritis, Rh | 1967 |
The use of 'normal' rats in studies on the acid mucopolysaccharides of lung.
Topics: Age Factors; Animals; Cesarean Section; Chondroitin; Connective Tissue; Heparin; Hyaluronic Acid; Hy | 1968 |
Lung hydroxyproline levels in mice exposed to cigarette smoke.
Topics: Animals; Collagen; Female; Hydroxyproline; Lung; Lung Diseases; Male; Mice; Nitrogen; Smoking; Time | 1969 |