hydroxyproline has been researched along with Diffuse Parenchymal Lung Disease in 7 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with PC-SOD at 10 mg/kg significantly reduced the hydroxyproline content and fibrosis score." | 3.69 | Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice. ( Hori, Y; Horie, K; Hoshino, J; Miyauchi, S; Mizuno, S; Sekiguchi, T; Yamazaki, C, 1997) |
| "IL-18-/- mice showed much worse lung injuries than wild-type mice, as assessed by the survival rate, histological images, and leukocyte infiltration in the bronchoalveolar lavage fluid and myeloperoxidase activity." | 1.33 | Protection against bleomycin-induced lung injury by IL-18 in mice. ( Adachi, S; Fujita, Y; Kashiwamura, S; Kubota, A; Nakatani-Okuda, A; Okamura, H; Sekiyama, A; Tanizawa, T; Tsuji, Y; Ueda, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, Y | 1 |
| Rong, M | 1 |
| Zhu, P | 1 |
| Chen, L | 1 |
| Fan, C | 1 |
| Wang, Y | 1 |
| Li, J | 1 |
| Fu, X | 1 |
| Zhao, L | 1 |
| Xiao, K | 1 |
| Wang, H | 1 |
| Wang, Z | 1 |
| Sun, L | 1 |
| Zhang, F | 1 |
| Zhang, X | 1 |
| Tang, F | 1 |
| He, W | 1 |
| Matsui, K | 1 |
| Ueda, H | 2 |
| Terada, M | 1 |
| Azuma, N | 1 |
| Okamura, H | 2 |
| Sano, H | 1 |
| Li, Y | 1 |
| Azuma, A | 1 |
| Takahashi, S | 1 |
| Usuki, J | 1 |
| Matsuda, K | 1 |
| Aoyama, A | 1 |
| Kudoh, S | 1 |
| Nakatani-Okuda, A | 1 |
| Kashiwamura, S | 1 |
| Sekiyama, A | 1 |
| Kubota, A | 1 |
| Fujita, Y | 1 |
| Adachi, S | 1 |
| Tsuji, Y | 1 |
| Tanizawa, T | 1 |
| Yamazaki, C | 2 |
| Hoshino, J | 2 |
| Hori, Y | 2 |
| Sekiguchi, T | 2 |
| Miyauchi, S | 2 |
| Mizuno, S | 2 |
| Horie, K | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy and Safety of Thalidomide in the Adjuvant Treatment of Moderate New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study[NCT04273529] | Phase 2 | 100 participants (Anticipated) | Interventional | 2020-02-20 | Not yet recruiting | ||
| The Efficacy and Safety of Thalidomide Combined With Low-dose Hormones in the Treatment of Severe New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study[NCT04273581] | Phase 2 | 40 participants (Anticipated) | Interventional | 2020-02-18 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for hydroxyproline and Diffuse Parenchymal Lung Disease
| Article | Year |
|---|---|
[The circulating fibrocytes are associated with the lung inflammation and fibrosis of mice with interstitial lung disease].
Topics: Actins; Animals; Arthritis, Experimental; Bleomycin; Collagen Type I; Female; Flow Cytometry; Hydrox | 2014 |
Thalidomide has a therapeutic effect on interstitial lung fibrosis: evidence from in vitro and in vivo studies.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Collagen Type | 2009 |
Thalidomide has a therapeutic effect on interstitial lung fibrosis: evidence from in vitro and in vivo studies.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Collagen Type | 2009 |
Thalidomide has a therapeutic effect on interstitial lung fibrosis: evidence from in vitro and in vivo studies.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Collagen Type | 2009 |
Thalidomide has a therapeutic effect on interstitial lung fibrosis: evidence from in vitro and in vivo studies.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Collagen Type | 2009 |
Mizoribine protects against bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Prol | 2010 |
Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Mode | 2002 |
Protection against bleomycin-induced lung injury by IL-18 in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Granulocyte-M | 2005 |
Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Disease Models, Animal; Fibrosis; Hydroxyprolin | 1997 |
Production of superoxide and nitric oxide by alveolar macrophages in the bleomycin-induced interstitial pneumonia mice model.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Disease Models, Animal; Hydroxyproline; Immunohistochemis | 1998 |