hydroxyproline has been researched along with Diabetes Mellitus, Type 1 in 18 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyproline excretion was increased in both types of diabetes: Type 1: 21 (10-36) (median (IQR) mumol mmol creatinine-1; Type 2: 25 (13-43) mumol mmol creatinine-1; control: 10 (6-22) mumol mmol creatinine-1 (p < 0." | 5.29 | Hydroxyproline excretion is increased in diabetes mellitus and related to the presence of microalbuminuria. ( Marshall, SM; Selby, PL; Shearing, PA, 1995) |
| "We observed that BMD in IDDM patients before 40 years old was significantly lower than in healthy subject." | 2.68 | [Bone mineralization in insulin-dependent diabetes mellitus]. ( Goliat, E; Lipińska, A; Marusza, W; Ostrowski, K, 1997) |
| "The hydroxyproline level was determined by means of high-performance liquid chromatography; the collagenase activity, by using a radiolabeled collagen substrate." | 1.32 | Decrease of collagen deposition in wound repair in type 1 diabetes independent of glycemic control. ( Agren, MS; Black, E; Gottrup, F; Holstein, PE; Jorgensen, LN; Madsen, SM; Perrild, H; Vibe-Petersen, J, 2003) |
| "We examined 60 IDDM patients (30 women without menstruation disturbances; 30 men; age 25-36 years old)." | 1.30 | [Microalbuminuria as a risk factor for diabetic osteopathy in patients with IDDM and renal sufficiency]. ( Goliat, E; Lipińska, A; Marusza, W; Ostrowski, K, 1998) |
| "Hydroxyproline excretion was increased in both types of diabetes: Type 1: 21 (10-36) (median (IQR) mumol mmol creatinine-1; Type 2: 25 (13-43) mumol mmol creatinine-1; control: 10 (6-22) mumol mmol creatinine-1 (p < 0." | 1.29 | Hydroxyproline excretion is increased in diabetes mellitus and related to the presence of microalbuminuria. ( Marshall, SM; Selby, PL; Shearing, PA, 1995) |
| "Therefore the pathogenesis of osteopenia in type 1 DM remains unclear, and requires further investigation." | 1.28 | Study of bone loss in diabetes mellitus type 1. ( Hawkins, F; Larrodera, L; Leon, M; Lledo, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Black, E | 1 |
| Vibe-Petersen, J | 1 |
| Jorgensen, LN | 1 |
| Madsen, SM | 1 |
| Agren, MS | 1 |
| Holstein, PE | 1 |
| Perrild, H | 1 |
| Gottrup, F | 1 |
| Klujber, L | 1 |
| Szücs, R | 1 |
| Baranyai, Z | 1 |
| Gabulya, J | 1 |
| Soltész, Gy | 1 |
| Tenni, R | 1 |
| Tavella, D | 1 |
| Donnelly, P | 1 |
| Di Ferrante, N | 1 |
| Hill, L | 1 |
| Leach, C | 1 |
| Hatton, D | 1 |
| Selby, PL | 1 |
| Shearing, PA | 1 |
| Marshall, SM | 1 |
| Olmos, JM | 2 |
| Pérez-Castrillón, JL | 1 |
| García, MT | 2 |
| Garrido, JC | 1 |
| Amado, JA | 2 |
| González-Macías, J | 2 |
| Gallacher, SJ | 1 |
| Fenner, JA | 1 |
| Fisher, BM | 1 |
| Quin, JD | 1 |
| Fraser, WD | 1 |
| Logue, FC | 1 |
| Cowan, RA | 1 |
| Boyle, IT | 1 |
| MacCuish, AC | 1 |
| Sayinalp, S | 1 |
| Gedik, O | 1 |
| Koray, Z | 1 |
| Goliat-Marusza, E | 1 |
| Wardyn, K | 1 |
| Stepniewski, M | 1 |
| Marusza, W | 3 |
| Billip-Tomecka, Z | 1 |
| Ostrowski, K | 3 |
| Odetti, P | 1 |
| Traverso, N | 1 |
| Cosso, L | 1 |
| Noberasco, G | 1 |
| Pronzato, MA | 1 |
| Marinari, UM | 1 |
| Goliat, E | 2 |
| Lipińska, A | 2 |
| Zywiec, J | 1 |
| Grzeszczak, W | 1 |
| Pierzchała, K | 1 |
| Błasiak, M | 1 |
| Kuska, J | 1 |
| Kokot, F | 1 |
| Irzyniec, T | 1 |
| Leon, M | 1 |
| Larrodera, L | 1 |
| Lledo, G | 1 |
| Hawkins, F | 1 |
| Mani, I | 1 |
| Mani, UV | 1 |
| el-Kishky, M | 1 |
| Mahfouz, SA | 1 |
| el-Habbak, SM | 1 |
| Goncerzewicz, M | 1 |
| Socha, J | 1 |
| Cichy, W | 1 |
| Nagadowska, J | 1 |
3 trials available for hydroxyproline and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Bone densitometry and biochemical bone remodeling markers in type 1 diabetes mellitus.
Topics: Acid Phosphatase; Adolescent; Adult; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Density; | 1994 |
[Disorders of bone tissue metabolism in patients in diabetes mellitus type one].
Topics: Adolescent; Adult; Bone Density; Bone Diseases, Metabolic; Calcium; Diabetes Mellitus, Type 1; Femal | 1996 |
[Bone mineralization in insulin-dependent diabetes mellitus].
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Bone and Bones; Bone Resorption; Calcification, | 1997 |
15 other studies available for hydroxyproline and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Decrease of collagen deposition in wound repair in type 1 diabetes independent of glycemic control.
Topics: Adult; Aged; Blood Glucose; Case-Control Studies; Collagen; Collagenases; Diabetes Mellitus, Type 1; | 2003 |
Glycosaminoglycan and hydroxyproline excretion in diabetic children.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis | 1982 |
Cultured fibroblasts of juvenile diabetics have excessively soluble pericellular collagen.
Topics: Cell Line; Collagen; Diabetes Mellitus, Type 1; Fibroblasts; Humans; Hydroxyproline; Skin; Solubilit | 1980 |
Hydroxyproline excretion is increased in diabetes mellitus and related to the presence of microalbuminuria.
Topics: Adult; Aged; Albuminuria; Biomarkers; Bone Resorption; Diabetes Mellitus, Type 1; Diabetes Mellitus, | 1995 |
An evaluation of bone density and turnover in premenopausal women with type 1 diabetes mellitus.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Density; Calci | 1993 |
Increasing serum osteocalcin after glycemic control in diabetic men.
Topics: Adult; Alkaline Phosphatase; Blood Glucose; C-Peptide; Calcium; Creatinine; Diabetes Mellitus, Type | 1995 |
Urine hydroxyproline increase in patients with diabetes mellitus.
Topics: Acid Phosphatase; Albuminuria; Alkaline Phosphatase; Biomarkers; Bone Resorption; Diabetes Mellitus, | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabe | 1996 |
[Microalbuminuria as a risk factor for diabetic osteopathy in patients with IDDM and renal sufficiency].
Topics: Absorptiometry, Photon; Adult; Albuminuria; Alkaline Phosphatase; Bone Density; Bone Diseases, Metab | 1998 |
[Bone complication in diabetes subjects with good metabolic control and without longterm complications: certain problems. Part II. Basal parameters of bone turnover].
Topics: Alkaline Phosphatase; Bone Resorption; Creatine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2001 |
[Selected indicators of calcium-phosphate metabolism in patients with diabetes mellitus].
Topics: Adult; Calcium; Circadian Rhythm; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Huma | 1989 |
Study of bone loss in diabetes mellitus type 1.
Topics: Alkaline Phosphatase; Blood Glucose; Blood Proteins; Bone and Bones; Bone Diseases, Metabolic; Bone | 1989 |
Urinary excretion of hydroxyproline in diabetics under different modes of treatment.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hydroxyproline; Hypogly | 1986 |
An in vitro study of hydroxyproline synthesis by gingival fibroblasts in patients with juvenile diabetes.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Fibroblasts; Gingiva; Humans; Hydroxyproline; Male | 1986 |
[Hydroxyproline indicators in the evaluation of nutritional status of children with various metabolic diseases].
Topics: Child; Child Nutrition Disorders; Diabetes Mellitus, Type 1; Endocrine System Diseases; Female; Huma | 1974 |