hydroxyproline has been researched along with Dermatoses in 45 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the antifibrotic effects of pomalidomide in preventive as well as therapeutic treatment regimes using bleomycin-induced dermal fibrosis as a model of early, inflammatory stages of fibrosis and the tight-skin mouse model as a model of later stages of fibrosis with endogenous activation of fibroblasts." | 7.78 | Pomalidomide is effective for prevention and treatment of experimental skin fibrosis. ( Beyer, C; Cedzik, D; Dees, C; Distler, A; Distler, JH; Distler, O; Palumbo-Zerr, K; Schafer, PH; Schett, G; Shankar, SL; Tomcik, M; Weingärtner, S; Zerr, P, 2012) |
| "We evaluated the antifibrotic effects of pomalidomide in preventive as well as therapeutic treatment regimes using bleomycin-induced dermal fibrosis as a model of early, inflammatory stages of fibrosis and the tight-skin mouse model as a model of later stages of fibrosis with endogenous activation of fibroblasts." | 3.78 | Pomalidomide is effective for prevention and treatment of experimental skin fibrosis. ( Beyer, C; Cedzik, D; Dees, C; Distler, A; Distler, JH; Distler, O; Palumbo-Zerr, K; Schafer, PH; Schett, G; Shankar, SL; Tomcik, M; Weingärtner, S; Zerr, P, 2012) |
| "Metformin (MET) has anti-inflammatory and anti-fibrotic effects, but its effect on the in vivo pathogenesis of scleroderma remains unknown." | 1.51 | Metformin attenuates bleomycin-induced scleroderma by regulating the balance of Treg/Teff cells and reducing spleen germinal center formation. ( Feng, M; Gao, C; Guo, H; Li, X; Liang, Z; Luo, J; Qin, K; Wang, Y; Zhang, S; Zhao, X, 2019) |
| "Laser-induced wounds, scars, and hyperpigmentation were evaluated by macroscopic, histologic, and biochemical examinations." | 1.30 | Ultraviolet exposure influences laser-induced wounds, scars, and hyperpigmentation: a murine study. ( Bech-Thomsen, N; Haedersdal, M; Poulsen, T; Wulf, HC, 1998) |
| "Hydroxylysine concentration was not changed in patients with generalized morphoea." | 1.27 | Collagen specific amino acids in skin in localized scleroderma. ( Ammitzbøll, T; Møller, R; Serup, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (84.44) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 2 (4.44) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Stegemann, A | 1 |
| Raker, V | 1 |
| Del Rey, A | 1 |
| Steinbrink, K | 1 |
| Böhm, M | 1 |
| Wang, Y | 1 |
| Zhang, S | 1 |
| Liang, Z | 1 |
| Feng, M | 1 |
| Zhao, X | 1 |
| Qin, K | 1 |
| Gao, C | 1 |
| Li, X | 1 |
| Guo, H | 1 |
| Luo, J | 1 |
| Geethalakshmi, R | 1 |
| Sakravarthi, C | 1 |
| Kritika, T | 1 |
| Arul Kirubakaran, M | 1 |
| Sarada, DV | 1 |
| Liu, S | 1 |
| Kapoor, M | 1 |
| Leask, A | 1 |
| Weingärtner, S | 1 |
| Zerr, P | 1 |
| Tomcik, M | 1 |
| Palumbo-Zerr, K | 1 |
| Distler, A | 1 |
| Dees, C | 1 |
| Beyer, C | 1 |
| Shankar, SL | 1 |
| Cedzik, D | 1 |
| Schafer, PH | 1 |
| Distler, O | 1 |
| Schett, G | 1 |
| Distler, JH | 1 |
| Değim, Z | 1 |
| Celebi, N | 1 |
| Sayan, H | 1 |
| Babül, A | 1 |
| Erdoğan, D | 1 |
| Take, G | 1 |
| KORTING, GW | 1 |
| HOLZMANN, H | 1 |
| Serup, J | 1 |
| Ammitzbøll, T | 1 |
| Møller, R | 1 |
| Oikarinen, A | 1 |
| Palatsi, R | 1 |
| Linna, SL | 1 |
| Peltonen, L | 1 |
| Duterque, M | 1 |
| Crouzet, J | 1 |
| Kouri, N | 1 |
| Nissen, HP | 1 |
| Kreysel, HW | 1 |
| Williams, ML | 1 |
| Elias, PM | 1 |
| Uitto, J | 2 |
| Bauer, EA | 2 |
| Santa-Cruz, DJ | 1 |
| Loewinger, RJ | 1 |
| Eisen, AZ | 1 |
| Haedersdal, M | 1 |
| Bech-Thomsen, N | 1 |
| Poulsen, T | 1 |
| Wulf, HC | 1 |
| Blumenkrantz, N | 1 |
| Ullman, S | 1 |
| Asboe-Hansen, G | 1 |
| Takeuchi, T | 1 |
| Langness, U | 1 |
| Nissen, R | 1 |
| Woodruff, CW | 1 |
| Kucharz, E | 1 |
| Drózdz, M | 1 |
| Laitinen, O | 2 |
| Ocaña, J | 1 |
| Pérez de Vargas, I | 1 |
| Wilhelmi, ML | 1 |
| Crespo, V | 1 |
| Pastor, R | 1 |
| Fajardo, FS | 1 |
| Delgado, ML | 1 |
| Kubota, Y | 1 |
| Fujiwara, K | 1 |
| Ogata, I | 1 |
| Hori, Y | 1 |
| Oka, H | 1 |
| Ichihashi, M | 1 |
| Shinkai, H | 1 |
| Takei, M | 1 |
| Sano, S | 1 |
| Fleischmajer, R | 1 |
| Shapiro, L | 1 |
| Raab, W | 1 |
| Lindner, J | 1 |
| Church, RL | 1 |
| Tanzer, ML | 1 |
| Lapiere, CM | 2 |
| Stancíková, M | 1 |
| Trnavský, K | 1 |
| Aalto, M | 1 |
| Kulonen, E | 1 |
| Kishihara, Y | 1 |
| Jackson, SH | 2 |
| Heininger, JA | 2 |
| Eberhagen, D | 1 |
| Mikol, F | 1 |
| Mikol, J | 1 |
| Leclere, J | 1 |
| Pinnell, SR | 1 |
| Krane, SM | 1 |
| Kenzora, JE | 1 |
| Glimcher, MJ | 1 |
| Prockop, DJ | 1 |
| Niejadlik, DC | 1 |
| Témime, P | 1 |
| Stahl, A | 1 |
| Nusgens, B | 1 |
| Black, MM | 1 |
| Bottoms, E | 1 |
| Shuster, S | 1 |
| Yamada, Y | 1 |
| Frommhold, W | 1 |
| Bublitz, G | 1 |
| Hanson, H | 1 |
| Wiederanders, B | 1 |
| Kivirikko, KI | 1 |
3 reviews available for hydroxyproline and Dermatoses
| Article | Year |
|---|---|
[Biosynthesis of collagen].
Topics: Adenocarcinoma, Scirrhous; Adult; Amino Acids; Animals; Ascorbic Acid; Cattle; Child; Collagen; Coll | 1975 |
Collagen in cutaneous diseases.
Topics: Collagen; Ehlers-Danlos Syndrome; Epidermolysis Bullosa; Glucocorticoids; Humans; Hydroxylysine; Hyd | 1979 |
Ascorbic acid--scurvy.
Topics: Adult; Age Factors; Anemia; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Bone Diseases, Develop | 1975 |
42 other studies available for hydroxyproline and Dermatoses
| Article | Year |
|---|---|
Expression of the α7 Nicotinic Acetylcholine Receptor Is Critically Required for the Antifibrotic Effect of PHA-543613 on Skin Fibrosis.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bleomycin; Bridged Bicyclo Compounds, Heterocyclic | 2022 |
Metformin attenuates bleomycin-induced scleroderma by regulating the balance of Treg/Teff cells and reducing spleen germinal center formation.
Topics: Animals; Bleomycin; Cell Differentiation; Collagen; Disease Models, Animal; Female; Fibrosis; Germin | 2019 |
Evaluation of antioxidant and wound healing potentials of Sphaeranthus amaranthoides Burm.f.
Topics: Animals; Antioxidants; Asteraceae; Biphenyl Compounds; Collagen; Flavonoids; Free Radical Scavengers | 2013 |
Rac1 expression by fibroblasts is required for tissue repair in vivo.
Topics: Actins; Animals; Blotting, Western; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Prolife | 2009 |
Pomalidomide is effective for prevention and treatment of experimental skin fibrosis.
Topics: Animals; Disease Models, Animal; Fibrosis; Hydroxyproline; Immunosuppressive Agents; Mice; Mice, Inb | 2012 |
An investigation on skin wound healing in mice with a taurine-chitosan gel formulation.
Topics: Animals; Antioxidants; Biocompatible Materials; Chemistry, Pharmaceutical; Chitin; Chitosan; Collage | 2002 |
[ON THE HYDROXYPROLINE EXCRETION IN THE URINE OF DERMATOLOGIC PATIENTS].
Topics: Collagen Diseases; Humans; Hydroxyproline; Joint Diseases; Melanoma; Neoplasms; Osteomalacia; Psoria | 1965 |
Collagen specific amino acids in skin in localized scleroderma.
Topics: Adolescent; Adult; Aged; Amino Acids; Collagen; Female; Humans; Hydroxylysine; Hydroxyproline; Male; | 1984 |
Types I and III collagens and the activities of prolyl hydroxylase and galactosylhydroxylysyl glucosyltransferase in skin lesions of tuberous sclerosis.
Topics: Adult; Collagen; Glucosyltransferases; Histiocytoma, Benign Fibrous; Humans; Hydroxyproline; Procoll | 1982 |
[Sclerodermiform lesions in Lobstein's disease].
Topics: Adult; Collagen; Diagnosis, Differential; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteoge | 1984 |
[Pathology and clinical aspects of impaired connective tissue metabolism of the skin].
Topics: Age Factors; Collagen; Connective Tissue Diseases; Glycosaminoglycans; Humans; Hydroxyproline; Skin; | 1982 |
Nature of skin fragility in patients receiving retinoids for systemic effect.
Topics: Adolescent; Adult; Animals; Blister; Child; Etretinate; Female; Humans; Hydroxyproline; Isomerism; I | 1981 |
Focal dermal hypoplasia: abnormal growth characteristics of skin fibroblasts in culture.
Topics: Adult; Cells, Cultured; Connective Tissue Diseases; Dental Enamel Hypoplasia; Female; Fibroblasts; H | 1980 |
Ultraviolet exposure influences laser-induced wounds, scars, and hyperpigmentation: a murine study.
Topics: Animals; Cicatrix; Contracture; Copper; Dermatologic Surgical Procedures; Esthetics; Facial Dermatos | 1998 |
Parallel studies on collagen hydroxyproline and hydroxylysine in human skin biopsies.
Topics: Adult; Biopsy; Child; Collagen; Humans; Hydroxylysine; Hydroxyproline; Middle Aged; Skin; Skin Disea | 1976 |
[Peptidyl prolyl hydroxylase activity in relation to the actual collagen biosynthesis in cotton pellet granuloma of guinea pig (author's transl)].
Topics: Animals; Collagen; Gossypium; Granuloma; Guinea Pigs; Hydroxyproline; Procollagen-Proline Dioxygenas | 1977 |
[Urinary hydroxylysine excretion as an index of systemic collagen disorders].
Topics: Bone Diseases; Collagen; Collagen Diseases; Female; Humans; Hydroxylysine; Hydroxyproline; Inflammat | 1977 |
Clinical applications of urinary hydroxyproline determination.
Topics: Adolescent; Adult; Age Factors; Aged; Bone Diseases; Chemistry Techniques, Analytical; Child; Collag | 1975 |
[Sclerodermiform porphyria cutanea tarda. Ultrastructural study].
Topics: Aged; Animals; Bicarbonates; Cricetinae; Diabetes Complications; Diagnosis, Differential; Hemorrhage | 1985 |
Collagen prolyl hydroxylase inhibitor and reduced collagen formation in cotton pellet-induced granuloma and skin wound healing in rats.
Topics: Animals; Anthraquinones; Collagen; Female; Granuloma; Hydroxyproline; Procollagen-Proline Dioxygenas | 1985 |
Analysis of the mechanism of bleomycin-induced cutaneous fibrosis in mice.
Topics: Animals; Bleomycin; Carbon Radioisotopes; Collagen; Hydroxyproline; Male; Mice; Microbial Collagenas | 1973 |
Hyaline reticuloxanthoma. The chemical nature of its hyaline.
Topics: Aged; Amino Acids; Collagen; Hexosamines; Hexoses; Histocytochemistry; Humans; Hyalin; Hydroxyprolin | 1968 |
[The clinical significance of urinary hydroxyproline determinations (author's transl)].
Topics: Alkaline Phosphatase; Animals; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Burns; Carbon R | 1972 |
[Catabolic enzymes of the connective tissue].
Topics: Aminopeptidases; Chondroitin; Collagen; Connective Tissue; Connective Tissue Cells; Enzymes; Galacto | 1972 |
Identification of two distinct species of procollagen synthesized by a clonal line of calf dermatosparactic cells.
Topics: Animals; Cattle; Cattle Diseases; Chromatography, DEAE-Cellulose; Clone Cells; Collagen; Electrophor | 1973 |
Collagenolytic enzymes and acid-proteinase activity in granuloma tissue.
Topics: Animals; Cathepsins; Collagen; Granuloma; Hydrogen-Ion Concentration; Hydroxyproline; Microbial Coll | 1974 |
Effects of serotonin, indomethacin and other antirheumatic drugs on the synthesis of collagen and other proteins in granulation tissue slices.
Topics: Animals; Bradykinin; Collagen; Epinephrine; Granulation Tissue; Granuloma; Histamine; Hydroxyproline | 1972 |
[Collagen-like protein in dermatology. 1. Collagen-like protein in the serum of normal subjects and patients with collagen diseases].
Topics: Adolescent; Adult; Child; Child, Preschool; Collagen; Collagen Diseases; Female; Humans; Hydroxyprol | 1972 |
A reassessment of the collagen reutilization theory by an isotope ratio method.
Topics: Animals; Carbon Radioisotopes; Collagen; Female; Glycine; Granuloma; Hydroxyproline; Isotope Labelin | 1973 |
[Letter: Significance of hydroxyproline secretion].
Topics: Adolescent; Adult; Bone Diseases; Child; Endocrine System Diseases; Female; Growth; Humans; Hydroxyp | 1973 |
A study of collagen reutilization using an 18O2 labeling technique.
Topics: Animals; Chromatography, Gas; Chromatography, Paper; Collagen; Granuloma; Hydroxyproline; Isotope La | 1974 |
[Aneurysmal dilatations of the internal carotid arteries and cutaneous calcinosis during systemic elastorrhexis. Trial treatment with calcitonin].
Topics: Adult; Alkaline Phosphatase; Aneurysm; Angioid Streaks; Bone and Bones; Calcinosis; Calcitonin; Calc | 1974 |
A heritable disorder of connective tissue. Hydroxylysine-deficient collagen disease.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Bone and Bones; Cartilage; Child; Collagen; Colla | 1972 |
A subtle disease and a dilemma: can cells secrete collagen that does not contain a sugar-tag?
Topics: Amino Acid Metabolism, Inborn Errors; Collagen; Collagen Diseases; Disaccharides; Galactose; Glucose | 1972 |
Hydroxyproline.
Topics: Bone and Bones; Bone Diseases; Bone Neoplasms; Burns; Collagen; Collagen Diseases; Fibrous Dysplasia | 1972 |
[Disabling ulcerated and extended scleroatrophic lichen].
Topics: Edema; Humans; Hydroxyproline; Leg Injuries; Lumbosacral Region; Male; Middle Aged; Purpura; Skin Di | 1971 |
[Torpid skin wounds and collagen metabolism disorder].
Topics: Child; Collagen; Collagen Diseases; Female; Humans; Hydroxyproline; Leg Ulcer; Peptides; Skin Diseas | 1969 |
Skin collagen content and thickness in systemic sclerosis.
Topics: Adult; Aged; Biopsy; Collagen; Diagnosis, Differential; Female; Humans; Hydroxyproline; Middle Aged; | 1970 |
[Investigation on urinary hydroxyproline--influence of skin collagen on urinary hydroxyproline and its adjustment by hydroxyproline--creatinine ratio].
Topics: Adolescent; Adult; Age Factors; Animals; Bone Neoplasms; Child; Child, Preschool; Collagen; Creatini | 1970 |
[Studies on subcutaneous fibroses following cobalt teletherapy and their treatment possibilities with dimethyl sulfoxide (DMSO)].
Topics: Cobalt Isotopes; Collagen; Connective Tissue; Dimethyl Sulfoxide; Female; Genital Neoplasms, Female; | 1967 |
[Fractionation of hydroxyproline-containing urinary peptides by Sephadex gel filtration].
Topics: Adolescent; Aminopropionitrile; Animals; Arthritis; Bone Diseases; Child; Child, Preschool; Chromato | 1969 |
Clinical significance of urinary hydroxyproline determinations in children.
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus; Humans; Hydroxyproline; Infant; Malabsorptio | 1965 |