hydroxyproline has been researched along with Crohn Disease in 6 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intestinal fibrosis is a common complication of Crohn's disease (CD)." | 1.48 | IL-17A Promotes Initiation and Development of Intestinal Fibrosis Through EMT. ( Guan, L; Li, Y; Sun, MJ; Zhang, HJ; Zhang, YN; Zhou, H, 2018) |
| "Intestinal fibrosis is thought to be a consequence of excessive tissue repair, and constitutes a common problem in patients with Crohn's disease (CD)." | 1.48 | Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis. ( Fagagnini, S; Hausmann, M; Hünerwadel, A; Jaeger, SU; Lutz, C; Mamie, C; Rogler, G; Ruiz, PA; Weder, B, 2018) |
| "Intestinal strictures in Crohn's disease are therefore characterized by an accumulation of collagen, a proliferation of smooth muscle cells, and an increase in type V collagen, a collagen type produced in relatively large amounts by smooth muscle cells." | 1.27 | Collagen content and types in the intestinal strictures of Crohn's disease. ( Diegelmann, RF; Elson, CO; Gay, R; Gay, S; Gotschalk, N; Graham, MF; Lindblad, WJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, HJ | 1 |
| Zhang, YN | 1 |
| Zhou, H | 1 |
| Guan, L | 1 |
| Li, Y | 1 |
| Sun, MJ | 1 |
| Hünerwadel, A | 1 |
| Fagagnini, S | 1 |
| Rogler, G | 1 |
| Lutz, C | 1 |
| Jaeger, SU | 1 |
| Mamie, C | 1 |
| Weder, B | 1 |
| Ruiz, PA | 1 |
| Hausmann, M | 1 |
| CRABBE, P | 1 |
| ISSELBACHER, KJ | 1 |
| Pokrovskiĭ, GA | 1 |
| Ilysheva, GN | 1 |
| Levitan, MKh | 1 |
| Chernomordik, AE | 1 |
| Shmykova, LM | 1 |
| Graham, MF | 1 |
| Diegelmann, RF | 1 |
| Elson, CO | 1 |
| Lindblad, WJ | 1 |
| Gotschalk, N | 1 |
| Gay, S | 1 |
| Gay, R | 1 |
| Motil, KJ | 1 |
| Altchuler, SI | 1 |
| Grand, RJ | 1 |
6 other studies available for hydroxyproline and Crohn Disease
| Article | Year |
|---|---|
IL-17A Promotes Initiation and Development of Intestinal Fibrosis Through EMT.
Topics: Animals; Cell Line; Colon; Crohn Disease; Epithelial-Mesenchymal Transition; Female; Fibrosis; Human | 2018 |
Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.
Topics: Animals; Colitis; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Hydroxyproline; | 2018 |
URINARY HYDROXYPROLINE EXCRETION IN MALABSORPTION STATES.
Topics: Alkaline Phosphatase; Celiac Disease; Collagen; Crohn Disease; Enteritis; Fluids and Secretions; Fra | 1965 |
[Changes in hydroxyprolinuria in patients with nonspecific ulcerative colitis and Crohn's disease].
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Hydroxyproline; Male; Middle Aged | 1980 |
Collagen content and types in the intestinal strictures of Crohn's disease.
Topics: Amino Acids; Colitis, Ulcerative; Collagen; Colon; Constriction, Pathologic; Crohn Disease; Electrop | 1988 |
Mineral balance during nutritional supplementation in adolescents with Crohn disease and growth failure.
Topics: Adolescent; Calcium, Dietary; Crohn Disease; Energy Metabolism; Food, Fortified; Growth; Humans; Hyd | 1985 |