hydroxyproline has been researched along with Cirrhoses, Experimental Liver in 199 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Liver fibrosis was induced in rats both with carbon tetrachloride and dimethylnitrosamine." | 7.68 | Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop ( Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E, 1992) |
| "Hepatic iron overload was associated with induction of heme oxygenase-1, a sensitive indicator of oxidative stress, and with modest increases in hydroxyproline and procollagen I mRNA levels without histologically evident fibrosis, all of which were unaffected by dietary fat." | 3.72 | Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats. ( Brown, KE; Brunt, EM; Dennery, PA; Fimmel, CJ; Kladney, RD; Ridnour, LA; Spitz, DR, 2003) |
| "Liver fibrosis was induced in rats both with carbon tetrachloride and dimethylnitrosamine." | 3.68 | Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop ( Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E, 1992) |
| " The value of serum procollagen type III peptide to body weight integrated over time (Kt) correlated linearly with hepatic hydroxyproline content (r = 0." | 3.67 | The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. ( Appelman, HD; Hahn, EG; Henley, KS; Kim, KY; Peters, KM; Rush, BD; Ruwart, MJ; Schuppan, D; Vidmar, TJ; Wilkinson, KF, 1989) |
| "Quercetin is a flavonoid with antifibrotic, and hepatoprotective properties." | 1.46 | Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats. ( Eskandari-Nasab, E; Ghoreshi, ZA; Kabirifar, R; Karimollah, A; Moradi, A; Safari, F, 2017) |
| "Zingerone treatment attenuated CCl4-induced increases in inflammatory mediators, including tumor necrosis factor-α, interleukin-1β, cyclooxygenase-2, and inducible nitric oxide synthase mRNA levels." | 1.43 | Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats. ( Bak, J; Cheong, KO; Chung, HY; Je, NK; Kim, KW; Lee, C; Moon, JO; Shin, DS; Yoon, S, 2016) |
| "(Betulaceae)." | 1.38 | The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation. ( Bai, T; Li, Q; Li, X; Lian, LH; Nan, JX; Ouyang, BQ; Wan, Y; Wu, YL; Xie, WX; Yang, N, 2012) |
| " Liver fibrosis in rats was induced by intraperitoneal injection of DMN for 4 weeks at the dosage 10 mg/kg body weight, once per day for 3 consecutive days in each week." | 1.38 | [Formula-syndrome correlation study of three classical anti-jaundice formulas in inhibition of liver fibrosis induced by dimethylnitrosamine in rats]. ( Bian, YQ; Cao, HY; Chen, GF; Liu, C; Liu, J; Liu, P; Lu, Y; Ning, BB; Sun, MY, 2012) |
| "Hydroxyproline content was decreased in both NIM811 groups compared with the model (P < 0." | 1.37 | N-methyl-4-isoleucine cyclosporine attenuates CCl -induced liver fibrosis in rats by interacting with cyclophilin B and D. ( Jia, J; Wang, H; Wang, T; You, H; Zhang, Y, 2011) |
| "Icaritin is an active ingredient extracted from the plant Herba Epimedium Sagittatum (Sieb." | 1.37 | Icaritin induces cell death in activated hepatic stellate cells through mitochondrial activated apoptosis and ameliorates the development of liver fibrosis in rats. ( Cao, L; Li, J; Liao, J; Liu, P; Qian, H; Wu, M; Xu, W; Yin, Z; Zhang, R, 2011) |
| "Glycogen was almost depleted by CCl4 but was partially preserved by trolox." | 1.35 | Trolox down-regulates transforming growth factor-beta and prevents experimental cirrhosis. ( Fernández-Martínez, E; Galicia-Moreno, M; Moreno, MG; Muriel, P; Pérez-Alvarez, VM; Reyes-Gordillo, K; Rodríguez-Rivera, A; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P, 2008) |
| " A threefold stimulation of collagen fractional synthesis was observed under the maximum dosage of carbon tetrachloride (CCl(4); 1." | 1.34 | Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions. ( Awada, M; Bautista, A; Gardner, JL; Hellerstein, MK; Lindwall, G; Turner, SM, 2007) |
| " After the 2-week CCl4 injection period, rats in the three siRNA groups simultaneously received a different dosage (0." | 1.34 | Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats. ( Hu, YB; Li, DG; Lu, HM, 2007) |
| "Curcumin treatment had no effect on pre existing liver cirrhosis." | 1.34 | Prevention of liver cirrhosis in rats by curcumin. ( Aeed, H; Ashkenazi, M; Bruck, R; Genina, O; Goldiner, I; Helpern, Z; Pines, M; Shapiro, H; Weiss, S, 2007) |
| "Tetrandrine was given orally to rats at doses of 5, 10 or 20 mg/kg for 4 wk compared with intraperitoneal injection of interferon-r." | 1.34 | Tetrandrine stimulates the apoptosis of hepatic stellate cells and ameliorates development of fibrosis in a thioacetamide rat model. ( Lian, LH; Nan, JX; Piao, DM; Yin, MF, 2007) |
| "Hydroxyproline was 504." | 1.34 | Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats. ( Cao, BQ; Chen, R; Huang, SB; Lin, JZ; Lin, N; Tang, ZF; Xiang, P; Xu, RY; Zhong, YS, 2007) |
| "Hepatic fibrosis was induced in BALB/c mice by repetitive intraperitoneal CCl4 injection." | 1.33 | Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice. ( Berres, ML; Gressner, AM; Grötzinger, J; Henkel, C; Matern, S; Roderfeld, M; Roeb, E; Wagner, S; Weiskirchen, R, 2006) |
| "Candesartan was administered orally for 21 days immediately after bile duct ligation to evaluate its preventive effect, and for 21 days starting 3 weeks after bile duct ligation to evaluate its therapeutic effect." | 1.33 | Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats. ( Koda, M; Matsunaga, Y; Murawaki, Y; Ueki, M; Yamamoto, S, 2006) |
| " 4 g x kg(-1) , two dosage groups) and Colchicine (0." | 1.33 | [Effect of Fuzheng Jiangan formula on liver fibrosis induced by albumin in rats]. ( Chen, YL; Cui, N; Huang, XA; Ren, Y; Song, CS; Sun, LH; Xu, HY, 2006) |
| "The hydroxyproline content was higher in CCl(4)-injured rats than in the control group (4." | 1.31 | S-adenosylmethionine prevents hepatic tocopherol depletion in carbon tetrachloride-injured rats. ( Ballesta, AM; Caballeria, J; Deulofeu, R; Gassó, M; Giménez, A; Mato, JM; Parés, A; Rodés, J; Román, J; Rubio, M; Varela-Moreiras, G, 2000) |
| "The aim of this study was to assess the effect of the early and chronic administration of octreotide in the prevention of hepatic fibrosis and portal hypertension (PHT)." | 1.30 | Antifibrotic and hemodynamic effects of the early and chronic administration of octreotide in two models of liver fibrosis in rats. ( Calès, P; Douay, O; Fort, J; Gallois, Y; Oberti, F; Pilette, C; Rosenbaum, J; Rousselet, MC; Veal, N, 1998) |
| "Treatment with ibuprofen (20 mg/kg." | 1.29 | Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium. ( Abou-Basha, L; Farag, MM; Salama, MA, 1995) |
| " N-acetyl-beta-glucosaminidase (beta-NAG) activity showed a similar change in the high dosage group." | 1.29 | [Effects of nifedipine on hepatic hyaluronic acid, hydroxyproline and glucosaminidase contents in rats with liver fibrosis]. ( Che, J; Li, D; Lu, H, 1994) |
| " No significant side effects were observed, despite a long-term administration of the acyclic retinoid." | 1.28 | Inhibitory effect of acyclic retinoid (polyprenoic acid) on hepatic fibrosis in CCl4-treated rats. ( Kato, M; Moriwaki, H; Muto, Y; Noma, A; Nozaki, Y; Okuno, M; Suzuki, Y; Tagaya, O, 1990) |
| "The drug metabolizing activity of rat liver during long-term administration of carbon tetrachloride (CCl4), and its relationship with the content of hydroxyproline (Hyp) in the liver were examined." | 1.27 | Drug metabolizing activity in rats with chronic liver injury induced by carbon tetrachloride: relationship with the content of hydroxyproline in the liver. ( Hazama, H; Murase, T; Okuno, H; Sameshima, Y; Shiozaki, Y, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (19.10) | 18.7374 |
| 1990's | 47 (23.62) | 18.2507 |
| 2000's | 76 (38.19) | 29.6817 |
| 2010's | 38 (19.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ho, HL | 1 |
| Huo, TI | 1 |
| Chang, T | 1 |
| Lee, WS | 1 |
| Hsin, IF | 1 |
| Lee, FY | 1 |
| Huang, HC | 1 |
| Hou, MC | 1 |
| Lee, SD | 1 |
| Zhang, Y | 2 |
| Miao, H | 1 |
| Yan, H | 1 |
| Sheng, Y | 1 |
| Ji, L | 1 |
| Peng, JH | 1 |
| Li, XM | 4 |
| Hu, YY | 5 |
| Feng, Q | 1 |
| Collins, BH | 1 |
| Holzknecht, ZE | 1 |
| Lynn, KA | 1 |
| Sempowski, GD | 1 |
| Smith, CC | 1 |
| Liu, S | 1 |
| Parker, W | 1 |
| Rockey, DC | 1 |
| Dong, W | 1 |
| Lv, B | 1 |
| Wei, F | 1 |
| Yang, L | 2 |
| Takahashi, K | 1 |
| Murata, S | 1 |
| Fukunaga, K | 1 |
| Ohkohchi, N | 1 |
| Yang, FR | 1 |
| Fang, BW | 2 |
| Lou, JS | 1 |
| Shaaban, AA | 1 |
| Shaker, ME | 1 |
| Zalata, KR | 1 |
| El-kashef, HA | 1 |
| Ibrahim, TM | 1 |
| Qian, Y | 1 |
| Fu, XC | 1 |
| Hu, R | 1 |
| Shen, LM | 1 |
| Bai, HB | 1 |
| Said, E | 1 |
| Said, SA | 1 |
| Gameil, NM | 1 |
| Ammar, EM | 1 |
| Bridle, KR | 1 |
| Sobbe, AL | 1 |
| de Guzman, CE | 1 |
| Santrampurwala, N | 1 |
| Jaskowski, LA | 1 |
| Clouston, AD | 1 |
| Campbell, CM | 1 |
| Nathan Subramaniam, V | 1 |
| Crawford, DH | 1 |
| He, W | 1 |
| Wang, B | 1 |
| Yang, J | 1 |
| Zhuang, Y | 1 |
| Wang, L | 7 |
| Huang, X | 1 |
| Chen, J | 2 |
| Mahmoud, MF | 1 |
| Swefy, SE | 1 |
| Hasan, RA | 1 |
| Ibrahim, A | 1 |
| Yu, FX | 1 |
| Teng, YY | 1 |
| Zhu, QD | 1 |
| Zhang, QY | 1 |
| Tang, YH | 1 |
| Gao, TJ | 1 |
| Dong, L | 1 |
| Shi, HT | 1 |
| Zhou, YN | 1 |
| Mu, YP | 4 |
| Fu, WW | 1 |
| Ning, BB | 3 |
| Du, GL | 2 |
| Chen, JM | 2 |
| Sun, MY | 2 |
| Zhang, H | 4 |
| Liu, CH | 3 |
| Xu, LM | 2 |
| Liu, P | 13 |
| Cheong, KO | 1 |
| Shin, DS | 1 |
| Bak, J | 1 |
| Lee, C | 1 |
| Kim, KW | 1 |
| Je, NK | 1 |
| Chung, HY | 1 |
| Yoon, S | 1 |
| Moon, JO | 1 |
| Song, YN | 1 |
| Zhang, GB | 1 |
| Lu, YY | 1 |
| Chen, QL | 1 |
| Wang, ZT | 1 |
| Su, SB | 1 |
| Zhou, Y | 1 |
| Tong, X | 2 |
| Ren, S | 2 |
| Wang, X | 1 |
| Mu, Y | 3 |
| Sun, M | 1 |
| Chen, G | 1 |
| Kabirifar, R | 1 |
| Ghoreshi, ZA | 1 |
| Safari, F | 1 |
| Karimollah, A | 1 |
| Moradi, A | 1 |
| Eskandari-Nasab, E | 1 |
| Kim, MY | 3 |
| Baik, SK | 3 |
| Jang, YO | 2 |
| Suk, KT | 2 |
| Kim, JW | 3 |
| Kim, HS | 2 |
| Cho, MY | 3 |
| Choi, SJ | 1 |
| Um, SH | 2 |
| Han, KH | 2 |
| Li, F | 2 |
| Sun, JY | 1 |
| Wang, JY | 2 |
| Du, SL | 1 |
| Lu, WY | 1 |
| Liu, M | 1 |
| Xie, C | 1 |
| Shi, JY | 1 |
| Zhao, XY | 2 |
| Wang, BE | 2 |
| Wang, TL | 2 |
| Galicia-Moreno, M | 2 |
| Rodríguez-Rivera, A | 1 |
| Reyes-Gordillo, K | 1 |
| Segovia, J | 1 |
| Shibayama, M | 1 |
| Tsutsumi, V | 1 |
| Vergara, P | 1 |
| Moreno, MG | 1 |
| Fernández-Martínez, E | 1 |
| Pérez-Alvarez, VM | 1 |
| Muriel, P | 3 |
| Du, G | 2 |
| Du, J | 1 |
| Wang, G | 1 |
| Long, A | 1 |
| Park, DH | 2 |
| Yea, CJ | 1 |
| Lee, IY | 1 |
| Kwon, SO | 2 |
| Ko, SB | 1 |
| Chang, SJ | 1 |
| Lai, JT | 1 |
| Hsieh, WT | 1 |
| Fang, HL | 2 |
| Lin, WC | 2 |
| Lubel, JS | 1 |
| Herath, CB | 1 |
| Tchongue, J | 1 |
| Grace, J | 1 |
| Jia, Z | 1 |
| Spencer, K | 1 |
| Casley, D | 1 |
| Crowley, P | 1 |
| Sievert, W | 1 |
| Burrell, LM | 1 |
| Angus, PW | 1 |
| Wu, XR | 1 |
| Wang, Q | 1 |
| Shi, SS | 1 |
| Guo, WD | 1 |
| El-Gamal, RR | 1 |
| Nada, SM | 1 |
| Moustafa, NE | 1 |
| Afify, HA | 1 |
| Fathy, GM | 1 |
| Metwally, S | 1 |
| Hamza, RS | 1 |
| Tan, XH | 1 |
| Li, CQ | 1 |
| Zou, SR | 1 |
| Xie, M | 1 |
| Zhang, AM | 1 |
| Li, WL | 1 |
| Li, XY | 1 |
| Huang, HF | 1 |
| Lei, CL | 1 |
| Zhang, Z | 1 |
| Liu, JY | 1 |
| Pinlaor, S | 1 |
| Prakobwong, S | 1 |
| Hiraku, Y | 1 |
| Pinlaor, P | 1 |
| Laothong, U | 1 |
| Yongvanit, P | 1 |
| Wang, JJ | 1 |
| Li, J | 3 |
| Shi, L | 1 |
| Lv, XW | 1 |
| Cheng, WM | 1 |
| Chen, YY | 1 |
| Du, SS | 1 |
| Qiang, M | 1 |
| Zeng, ZC | 1 |
| Zhou, J | 1 |
| Tan, YS | 1 |
| Zhang, ZY | 1 |
| Zeng, HY | 1 |
| Liu, ZS | 1 |
| Wang, H | 4 |
| Wang, T | 1 |
| You, H | 1 |
| Jia, J | 1 |
| Rosenberg, P | 1 |
| Sjöström, M | 1 |
| Söderberg, C | 1 |
| Kinnman, N | 1 |
| Stål, P | 1 |
| Hultcrantz, R | 1 |
| Zhang, R | 1 |
| Cao, L | 1 |
| Qian, H | 1 |
| Liao, J | 1 |
| Xu, W | 1 |
| Wu, M | 1 |
| Yin, Z | 1 |
| El-Lakkany, NM | 1 |
| El-Maadawy, W | 1 |
| Ain-Shoka, A | 1 |
| Badawy, A | 1 |
| Hammam, O | 1 |
| Ebeid, F | 1 |
| Ping, J | 1 |
| Gao, AM | 1 |
| Xu, D | 1 |
| Li, RW | 1 |
| Chen, GF | 3 |
| Lu, Y | 2 |
| Sun, WY | 3 |
| Liu, H | 1 |
| Li, X | 2 |
| Wei, W | 3 |
| Favari, L | 1 |
| Wan, Y | 1 |
| Wu, YL | 1 |
| Lian, LH | 2 |
| Xie, WX | 1 |
| Ouyang, BQ | 1 |
| Bai, T | 1 |
| Li, Q | 2 |
| Yang, N | 1 |
| Nan, JX | 6 |
| Lu, S | 1 |
| Cheng, ML | 1 |
| Li, H | 1 |
| Wu, J | 1 |
| Wang, YP | 1 |
| Zhang, X | 1 |
| Zhang, LJ | 1 |
| Zhang, WM | 1 |
| Kim, HG | 1 |
| Han, JM | 1 |
| Lee, HW | 1 |
| Lee, JS | 1 |
| Son, SW | 1 |
| Choi, MK | 1 |
| Lee, DS | 1 |
| Wang, JH | 1 |
| Son, CG | 1 |
| Bian, YQ | 1 |
| Cao, HY | 1 |
| Liu, C | 5 |
| Liu, J | 3 |
| Sakaida, I | 9 |
| Hironaka, K | 2 |
| Terai, S | 2 |
| Okita, K | 9 |
| Li, C | 2 |
| Luo, J | 1 |
| Li, L | 2 |
| Cheng, M | 1 |
| Huang, N | 1 |
| Waalkes, MP | 1 |
| Oe, S | 1 |
| Fukunaka, Y | 1 |
| Hirose, T | 1 |
| Yamaoka, Y | 1 |
| Tabata, Y | 1 |
| Oh, WY | 1 |
| Pyo, S | 1 |
| Lee, KR | 1 |
| Lee, BK | 1 |
| Shin, DH | 1 |
| Cho, SI | 1 |
| Lee, SM | 1 |
| Kanno, K | 1 |
| Tazuma, S | 1 |
| Chayama, K | 1 |
| Brown, KE | 1 |
| Dennery, PA | 1 |
| Ridnour, LA | 1 |
| Fimmel, CJ | 1 |
| Kladney, RD | 1 |
| Brunt, EM | 1 |
| Spitz, DR | 1 |
| Deheza, R | 1 |
| Jinhua, S | 1 |
| Uchida, K | 4 |
| BOTTIGLIONI, E | 2 |
| ORLANDI, G | 2 |
| STURANI, PL | 2 |
| ARNOLD, H | 1 |
| DELBRUECK, A | 1 |
| HARTMANN, F | 1 |
| ITURRIAGA, H | 4 |
| PIZZI, T | 1 |
| UGARTE, G | 3 |
| LORCA, F | 1 |
| Bruck, R | 3 |
| Schey, R | 1 |
| Aeed, H | 3 |
| Hochman, A | 1 |
| Genina, O | 2 |
| Pines, M | 3 |
| Vázquez-Gil, MJ | 1 |
| Mesonero, MJ | 1 |
| Flores, O | 1 |
| Criado, M | 1 |
| Hidalgo, F | 1 |
| Arévalo, MA | 1 |
| Sánchez-Rodríguez, A | 1 |
| Tuñón, MJ | 1 |
| López-Novoa, JM | 1 |
| Esteller, A | 1 |
| Yao, HW | 1 |
| Chen, JQ | 1 |
| Xu, SY | 2 |
| Reif, S | 1 |
| Shilo, Y | 1 |
| Reich, R | 1 |
| Kloog, Y | 1 |
| Kweon, YO | 1 |
| Wang, LC | 2 |
| Lei, BJ | 1 |
| Zhao, JB | 1 |
| Fiorucci, S | 1 |
| Antonelli, E | 1 |
| Rizzo, G | 1 |
| Renga, B | 1 |
| Mencarelli, A | 1 |
| Riccardi, L | 1 |
| Orlandi, S | 1 |
| Pellicciari, R | 1 |
| Morelli, A | 1 |
| Yoshiji, H | 1 |
| Kuriyama, S | 1 |
| Noguchi, R | 1 |
| Yoshii, J | 1 |
| Ikenaka, Y | 1 |
| Yanase, K | 1 |
| Namisaki, T | 1 |
| Kitade, M | 1 |
| Yamazaki, M | 1 |
| Tsujinoue, H | 1 |
| Fukui, H | 1 |
| Jiang, W | 1 |
| Yang, CQ | 1 |
| Liu, WB | 1 |
| Wang, YQ | 1 |
| He, BM | 1 |
| Jin, H | 1 |
| Tsuchiya, M | 1 |
| Miyazaki, T | 1 |
| Karube, M | 1 |
| Matsuzaki, Y | 1 |
| Ikegami, T | 1 |
| Doy, M | 1 |
| Tanaka, N | 1 |
| Bouscarel, B | 1 |
| Wang, NP | 1 |
| Gui, SY | 2 |
| Wu, L | 2 |
| Wang, XN | 1 |
| Zhu, DY | 1 |
| Liu, Y | 2 |
| Di Vinicius, I | 1 |
| Baptista, AP | 1 |
| Barbosa, AA | 2 |
| Andrade, ZA | 4 |
| Tasci, I | 2 |
| Mas, MR | 2 |
| Vural, SA | 2 |
| Comert, B | 2 |
| Alcigir, G | 2 |
| Serdar, M | 1 |
| Mas, N | 2 |
| Isik, AT | 2 |
| Ates, Y | 1 |
| Zhao, LS | 1 |
| Tang, H | 2 |
| Roderfeld, M | 1 |
| Weiskirchen, R | 1 |
| Wagner, S | 1 |
| Berres, ML | 1 |
| Henkel, C | 1 |
| Grötzinger, J | 1 |
| Gressner, AM | 1 |
| Matern, S | 1 |
| Roeb, E | 1 |
| Xu, L | 1 |
| Dong, Z | 1 |
| Shen, H | 1 |
| Ma, H | 1 |
| Jia, JD | 3 |
| Long, AH | 1 |
| Fujisawa, G | 1 |
| Muto, S | 1 |
| Okada, K | 1 |
| Kusano, E | 1 |
| Ishibashi, S | 1 |
| Paul, SC | 1 |
| Lv, P | 1 |
| Xiao, YJ | 1 |
| An, P | 1 |
| Liu, SQ | 1 |
| Luo, HS | 1 |
| Gomes, AT | 2 |
| Bastos, CG | 2 |
| Afonso, CL | 1 |
| Medrado, BF | 2 |
| Potter, JJ | 2 |
| Rennie-Tankersley, L | 1 |
| Novitskiy, G | 1 |
| Sipes, J | 1 |
| Mezey, E | 2 |
| Xu, KS | 1 |
| Zhou, X | 1 |
| Ueki, M | 1 |
| Koda, M | 4 |
| Yamamoto, S | 1 |
| Matsunaga, Y | 1 |
| Murawaki, Y | 5 |
| Huang, XA | 1 |
| Sun, LH | 1 |
| Song, CS | 1 |
| Cui, N | 1 |
| Chen, YL | 1 |
| Xu, HY | 1 |
| Ren, Y | 1 |
| Cunha, LM | 1 |
| Assis, BC | 1 |
| Zhao, L | 1 |
| Liu, L | 1 |
| Yao, F | 1 |
| Gardner, JL | 1 |
| Turner, SM | 1 |
| Bautista, A | 1 |
| Lindwall, G | 1 |
| Awada, M | 1 |
| Hellerstein, MK | 1 |
| Hu, YB | 1 |
| Li, DG | 1 |
| Lu, HM | 1 |
| Ashkenazi, M | 1 |
| Weiss, S | 1 |
| Goldiner, I | 1 |
| Shapiro, H | 1 |
| Helpern, Z | 1 |
| Choi, YH | 1 |
| Rhim, DW | 1 |
| Kim, CH | 1 |
| Ahn, SC | 1 |
| Yin, MF | 1 |
| Piao, DM | 1 |
| Cao, BQ | 1 |
| Lin, JZ | 1 |
| Zhong, YS | 1 |
| Huang, SB | 1 |
| Lin, N | 1 |
| Tang, ZF | 1 |
| Chen, R | 1 |
| Xiang, P | 1 |
| Xu, RY | 1 |
| Lai, JJ | 1 |
| Lin, WL | 1 |
| Abdel Aziz, MT | 1 |
| Atta, HM | 1 |
| Mahfouz, S | 1 |
| Fouad, HH | 1 |
| Roshdy, NK | 1 |
| Ahmed, HH | 1 |
| Rashed, LA | 1 |
| Sabry, D | 1 |
| Hassouna, AA | 1 |
| Hasan, NM | 1 |
| Deveci, S | 1 |
| Akay, C | 1 |
| Bozdayi, M | 1 |
| Yurdaydin, C | 1 |
| Bozkaya, H | 1 |
| Uzunalimoglu, O | 1 |
| Said, HM | 1 |
| Tanabe, J | 1 |
| Izawa, A | 1 |
| Takemi, N | 1 |
| Miyauchi, Y | 1 |
| Torii, Y | 1 |
| Tsuchiyama, H | 1 |
| Suzuki, T | 1 |
| Sone, S | 1 |
| Ando, K | 1 |
| Wu, LM | 1 |
| Wu, XX | 1 |
| Sun, Y | 1 |
| Kong, XW | 1 |
| Zhang, YH | 1 |
| Xu, Q | 1 |
| Knorr, A | 1 |
| Hirth-Dietrich, C | 1 |
| Alonso-Alija, C | 1 |
| Härter, M | 1 |
| Hahn, M | 1 |
| Keim, Y | 1 |
| Wunder, F | 1 |
| Stasch, JP | 1 |
| Ohayon, O | 1 |
| Mawasi, N | 1 |
| Pevzner, A | 1 |
| Tryvitz, A | 1 |
| Gildor, T | 1 |
| Rojkind, M | 5 |
| Paizi, M | 1 |
| Spira, G | 1 |
| Anstee, QM | 1 |
| Goldin, RD | 1 |
| Wright, M | 1 |
| Martinelli, A | 1 |
| Cox, R | 1 |
| Thursz, MR | 1 |
| Eugenia, M | 1 |
| Pereda, T | 1 |
| Trivedi, P | 1 |
| Mowat, AP | 1 |
| Siegers, CP | 1 |
| Reichl, W | 1 |
| Katoh, M | 2 |
| Sugimoto, T | 2 |
| Ehrinpreis, MN | 1 |
| Giambrone, MA | 1 |
| Farag, MM | 1 |
| Salama, MA | 1 |
| Abou-Basha, L | 1 |
| Tsukamoto, H | 1 |
| Horne, W | 1 |
| Kamimura, S | 1 |
| Niemelä, O | 1 |
| Parkkila, S | 1 |
| Ylä-Herttuala, S | 1 |
| Brittenham, GM | 1 |
| Seifert, WF | 2 |
| Bosma, A | 2 |
| Hendriks, HF | 2 |
| van Leeuwen, RE | 2 |
| van Thiel-de Ruiter, GC | 2 |
| Seifert-Bock, I | 2 |
| Knook, DL | 2 |
| Brouwer, A | 2 |
| Che, J | 1 |
| Lu, H | 1 |
| Li, D | 1 |
| Kubota, M | 2 |
| Kayano, K | 3 |
| Takenaka, K | 2 |
| Mori, K | 1 |
| Aisen, AM | 1 |
| Doi, K | 1 |
| Swanson, SD | 1 |
| Yamamoto, H | 2 |
| Kawasaki, H | 2 |
| Yamane, M | 1 |
| Tanaka, Y | 1 |
| Marumo, F | 1 |
| Sato, C | 1 |
| Roholl, PJ | 1 |
| Geraci, JP | 1 |
| Mariano, MS | 1 |
| Zhang, M | 1 |
| Song, G | 1 |
| Minuk, GY | 1 |
| Matsumura, Y | 4 |
| Gerling, B | 1 |
| Becker, M | 1 |
| Waldschmidt, J | 1 |
| Rehmann, M | 1 |
| Schuppan, D | 4 |
| Adewusi, OI | 1 |
| Nix, NA | 1 |
| Lu, X | 1 |
| Colley, DG | 1 |
| Secor, WE | 1 |
| Buko, V | 1 |
| Lukivskaya, O | 1 |
| Nikitin, V | 1 |
| Kuryan, A | 1 |
| Dargel, R | 2 |
| Park, EJ | 4 |
| Ko, G | 4 |
| Kim, J | 1 |
| Sohn, DH | 5 |
| Picardi, A | 1 |
| de Oliveira, AC | 1 |
| Muguerza, B | 1 |
| Tosar, A | 1 |
| Quiroga, J | 1 |
| Castilla-Cortázar, I | 1 |
| Santidrián, S | 1 |
| Prieto, J | 1 |
| Matsuda, Y | 1 |
| Matsumoto, K | 1 |
| Yamada, A | 1 |
| Ichida, T | 1 |
| Asakura, H | 1 |
| Komoriya, Y | 1 |
| Nishiyama, E | 1 |
| Nakamura, T | 1 |
| Kimura, T | 1 |
| Ishihara, T | 1 |
| Hinz, S | 1 |
| Franke, H | 1 |
| Machnik, G | 1 |
| Müller, A | 1 |
| Akiyama, S | 1 |
| Hayashi, K | 1 |
| Ishige, A | 1 |
| Yamashita, Y | 1 |
| Shiota, A | 1 |
| Fujise, N | 1 |
| Ogawa, H | 1 |
| Masunaga, H | 1 |
| Yasuda, H | 1 |
| Higashio, K | 1 |
| Iredale, JP | 1 |
| Benyon, RC | 1 |
| Pickering, J | 1 |
| McCullen, M | 1 |
| Northrop, M | 1 |
| Pawley, S | 1 |
| Hovell, C | 1 |
| Arthur, MJ | 1 |
| Suzuki, C | 1 |
| Fort, J | 2 |
| Oberti, F | 2 |
| Pilette, C | 2 |
| Veal, N | 2 |
| Gallois, Y | 2 |
| Douay, O | 2 |
| Rousselet, MC | 1 |
| Rosenbaum, J | 1 |
| Calès, P | 2 |
| Okazaki, T | 1 |
| Hirota, S | 1 |
| Xu, ZD | 1 |
| Maeyama, K | 1 |
| Nakama, A | 1 |
| Kawano, S | 1 |
| Hori, M | 1 |
| Kitamura, Y | 1 |
| Cho, JJ | 2 |
| Lee, YS | 1 |
| Poo, JL | 1 |
| Jiménez, W | 1 |
| María Muñoz, R | 1 |
| Bosch-Marcé, M | 1 |
| Bordas, N | 1 |
| Morales-Ruiz, M | 1 |
| Pérez, M | 1 |
| Deulofeu, R | 2 |
| Solé, M | 1 |
| Arroyo, V | 1 |
| Rodés, J | 2 |
| Sugihara, A | 1 |
| Tsujimura, T | 1 |
| Fujita, Y | 1 |
| Nakata, Y | 1 |
| Terada, N | 1 |
| Cabré, M | 1 |
| Ferré, N | 1 |
| Folch, J | 1 |
| Paternain, JL | 1 |
| Hernàndez, M | 1 |
| del Castillo, D | 1 |
| Joven, J | 1 |
| Camps, J | 1 |
| Madden, JW | 1 |
| Gertman, PM | 1 |
| Peacock, EE | 1 |
| Ono, M | 1 |
| Miyamura, M | 1 |
| Kyotani, S | 1 |
| Saibara, T | 1 |
| Ohnishi, S | 1 |
| Nishioka, Y | 1 |
| Valerio, LG | 1 |
| Petersen, DR | 1 |
| Sarin, SK | 1 |
| Sharma, G | 1 |
| Banerjee, S | 1 |
| Kathayat, R | 1 |
| Malhotra, V | 1 |
| Kim, HJ | 1 |
| Hocher, B | 1 |
| Herbst, H | 1 |
| Ruehl, M | 1 |
| Hahn, EG | 3 |
| Riecken, EO | 2 |
| Jose, JK | 1 |
| Kuttan, R | 1 |
| Parés, A | 1 |
| Rubio, M | 1 |
| Gassó, M | 1 |
| Román, J | 1 |
| Giménez, A | 1 |
| Varela-Moreiras, G | 1 |
| Caballeria, J | 1 |
| Ballesta, AM | 1 |
| Mato, JM | 1 |
| Lee, SH | 2 |
| Park, PH | 1 |
| Kim, JY | 1 |
| Souza, MM | 1 |
| Paraná, R | 1 |
| Trepo, C | 1 |
| Oliveira, I | 1 |
| Chen, W | 1 |
| Wang, Z | 1 |
| Hu, Y | 2 |
| Sun, K | 1 |
| Chen, X | 1 |
| Liu, W | 1 |
| Chen, N | 1 |
| Chu, Y | 1 |
| Xie, F | 1 |
| Raetsch, C | 1 |
| Boigk, G | 1 |
| Bauer, M | 1 |
| Zhu, D | 1 |
| Kim, YC | 1 |
| Siegel, RC | 1 |
| Chen, KH | 1 |
| Greenspan, JS | 1 |
| Aguiar, JM | 1 |
| McPhie, JL | 1 |
| Short, LT | 1 |
| Bazin, S | 1 |
| Briquelet, N | 1 |
| Allain, JC | 1 |
| Delaunay, A | 1 |
| Häkkinen, HM | 1 |
| Franssila, K | 1 |
| Kulonen, E | 1 |
| Takase, S | 1 |
| Takada, A | 2 |
| Urashima, S | 1 |
| Enyama, K | 1 |
| Fujii, M | 1 |
| Suzuki, K | 1 |
| Hayashi, N | 1 |
| Sasaki, Y | 1 |
| Kono, M | 1 |
| Kasahara, A | 1 |
| Fusamoto, H | 1 |
| Imai, Y | 1 |
| Kamada, T | 1 |
| Ala-Kokko, L | 1 |
| Günzler, V | 1 |
| Hoek, JB | 1 |
| Rubin, E | 2 |
| Prockop, DJ | 3 |
| Van Gool, J | 2 |
| Van Tiel, D | 1 |
| Doenhoff, MJ | 1 |
| Van Vugt, H | 2 |
| Yoshitake, I | 1 |
| Ohishi, E | 1 |
| Sano, J | 1 |
| Mori, T | 1 |
| Kubo, K | 1 |
| Ogata, I | 1 |
| Mochida, S | 1 |
| Tomiya, T | 1 |
| Fujiwara, K | 1 |
| Cerbón-Ambriz, J | 2 |
| Cerbón-Solórzano, J | 1 |
| Okuno, M | 1 |
| Muto, Y | 1 |
| Moriwaki, H | 1 |
| Kato, M | 1 |
| Noma, A | 1 |
| Tagaya, O | 1 |
| Nozaki, Y | 1 |
| Suzuki, Y | 1 |
| Yamada, S | 1 |
| Hirayama, C | 2 |
| Casini, A | 1 |
| Lippe, IT | 1 |
| Evangelista, S | 1 |
| Geppetti, P | 1 |
| Santicioli, P | 1 |
| Urso, C | 1 |
| Paglierani, M | 1 |
| Maggi, CA | 1 |
| Surrenti, C | 1 |
| Szende, B | 1 |
| Jeney, A | 1 |
| Lapis, K | 1 |
| Emonard, H | 1 |
| Grimaud, JA | 1 |
| Ruwart, MJ | 1 |
| Wilkinson, KF | 1 |
| Rush, BD | 1 |
| Vidmar, TJ | 1 |
| Peters, KM | 1 |
| Henley, KS | 1 |
| Appelman, HD | 1 |
| Kim, KY | 1 |
| Cerbón, J | 1 |
| González, E | 2 |
| Perez-Tamayo, R | 1 |
| Montfort, I | 1 |
| Igarashi, S | 1 |
| Hatahara, T | 1 |
| Nagai, Y | 1 |
| Hori, H | 1 |
| Sakakibara, K | 1 |
| Sakai, A | 1 |
| Ono, J | 1 |
| Nohara, T | 1 |
| Nakase, A | 1 |
| de Nie, I | 1 |
| Okuno, H | 1 |
| Hazama, H | 1 |
| Murase, T | 1 |
| Shiozaki, Y | 1 |
| Sameshima, Y | 1 |
| Pierce, RA | 1 |
| Glaug, MR | 1 |
| Greco, RS | 1 |
| Mackenzie, JW | 1 |
| Boyd, CD | 1 |
| Deak, SB | 1 |
| Xu, ML | 1 |
| Ma, DY | 1 |
| Wei, CC | 1 |
| Xu, ZY | 1 |
| Xu, PP | 1 |
| Ge, SD | 1 |
| Lu, ML | 1 |
| Porta, EA | 2 |
| Hartroft, WS | 2 |
| Kock, OR | 1 |
| Becker, K | 1 |
| Delbrück, A | 1 |
| Takeuchi, T | 2 |
| Kivirikko, KI | 1 |
| Shaba, JK | 1 |
| Ranek, L | 1 |
| Bremmelgaard, A | 1 |
| Dupont, B | 1 |
| Jorgensen, M | 1 |
| Keiding, S | 1 |
| Thomsen, P | 1 |
| Tyrsted, G | 1 |
| Hutterer, F | 1 |
| Eisenstadt, M | 1 |
| Kekomäki, M | 1 |
| Schwartz, AL | 1 |
| Pentikäinen, P | 1 |
| Peterman, M | 2 |
| Iriarte, P | 1 |
| Huberman, A | 1 |
| Recio, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.[NCT03453918] | 41 participants (Actual) | Interventional | 2018-04-09 | Completed | |||
| Umbilical Cord Mesenchymal Stem Cell Transfusion in Patients With Severe Liver Cirrhosis[NCT01233102] | Phase 1/Phase 2 | 200 participants (Anticipated) | Interventional | 2009-10-31 | Suspended | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
199 other studies available for hydroxyproline and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Ascorbate lacks significant influence in rats with bile duct ligation-induced liver injury.
Topics: Animals; Ascorbic Acid; Bile Ducts; Body Weight; Hydroxyproline; Ligation; Liver Cirrhosis, Experime | 2017 |
Hepatoprotective effect of Forsythiae Fructus water extract against carbon tetrachloride-induced liver fibrosis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cadherins; Chemical and Drug Induced Liv | 2018 |
[Effect of cordyceps polysaccharide on lipid peroxidation of rats with dimethylnitrosamine-induced liver fibrosis].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Collagen; Cordyceps; | 2013 |
Association of age-dependent liver injury and fibrosis with immune cell populations.
Topics: Age Factors; Aging; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced L | 2013 |
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats.
Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemica | 2013 |
Human platelets inhibit liver fibrosis in severe combined immunodeficiency mice.
Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Caspase 3; Hepatocyte Growth Factor; Hepatocytes; | 2013 |
Effects of Fufang Biejia Ruangan pills on hepatic fibrosis in vivo and in vitro.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Cell C | 2013 |
Modulation of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis by olmesartan and omega-3.
Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Drug Therapy, Combination; Fatty Acids, Omega-3; | 2014 |
[Effects of Corbrin Shugan capsule on dimethylnitrosamine-induced hepatic fibrosis in rats].
Topics: Albumins; Animals; Capsules; Collagen Type III; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyp | 2013 |
Modulation of thioacetamide-induced liver fibrosis/cirrhosis by sildenafil treatment.
Topics: Animals; Collagen; Disease Progression; Hydroxyproline; Liver; Liver Cirrhosis; Liver Cirrhosis, Exp | 2013 |
Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2⁻/⁻ mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; ATP Bind | 2015 |
Chloroquine improved carbon tetrachloride-induced liver fibrosis through its inhibition of the activation of hepatic stellate cells: role of autophagy.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Autophagy; Carbon Tetrachloride; | 2014 |
Role of cannabinoid receptors in hepatic fibrosis and apoptosis associated with bile duct ligation in rats.
Topics: Animals; Apoptosis; Bile Ducts; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cho | 2014 |
Inhibitory effects of capsaicin on hepatic stellate cells and liver fibrosis.
Topics: Animals; Apoptosis; Capsaicin; Caspase 3; Cell Proliferation; Cells, Cultured; Collagen Type III; He | 2014 |
[Effect of alcohol extract of Plumula Nelumbini on carbon tetrachloride induced rat liver fibrosis: an experimental study].
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Collagen; Drugs, Chinese Herbal; Ethanol; Hepat | 2014 |
Yiguanjian decoction and its ingredients inhibit angiogenesis in carbon tetrachloride-induced cirrhosis mice.
Topics: Actins; Angiogenesis Inhibitors; Animals; Carbon Tetrachloride; Collagen; Drugs, Chinese Herbal; Hyd | 2015 |
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; | 2016 |
Huangqi decoction alleviates dimethylnitrosamine-induced liver fibrosis: An analysis of bile acids metabolic mechanism.
Topics: Animals; Astragalus propinquus; Bile Acids and Salts; Biomarkers; Cell Proliferation; Chemical and D | 2016 |
Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
Topics: Actins; Animals; Astragalus Plant; Cell Line; Cell Survival; Collagen Type I; Common Bile Duct; Dime | 2016 |
Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats.
Topics: Actins; Animals; Antioxidants; Catalase; Cholestasis; Collagen Type I; Cytoprotection; Down-Regulati | 2017 |
[Serum hyaluronic acid level: correlation with quantitative measurement of hepatic fibrosis in a cirrhotic rat model].
Topics: Animals; Bile Ducts; Biomarkers; Collagen; Hyaluronic Acid; Hydroxyproline; Ligation; Liver; Liver C | 2008 |
Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis.
Topics: Animals; Apoptosis; Collagen Type I; Collagen Type I, alpha 1 Chain; Drug Carriers; Hepatocyte Growt | 2008 |
Newly proposed fibrosis staging criterion for assessing carbon tetrachloride- and albumin complex-induced liver fibrosis in rodents.
Topics: Animals; Antigen-Antibody Complex; Carbon Tetrachloride; Humans; Hydroxyproline; Image Processing, C | 2008 |
Trolox down-regulates transforming growth factor-beta and prevents experimental cirrhosis.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Blotting, Western; Carbon Tetrach | 2008 |
Action mechanism of Yi Guan Jian Decoction on CCl4 induced cirrhosis in rats.
Topics: Administration, Oral; Animals; Apoptosis; Carbon Tetrachloride; Drugs, Chinese Herbal; Hepatic Stell | 2009 |
Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting En | 2008 |
The protective effects of a fermented substance from Saccharomyces cerevisiae on carbon tetrachloride-induced liver damage in rats.
Topics: Animals; Carbon Tetrachloride; Collagen Type I; Dose-Response Relationship, Drug; Fermentation; Hydr | 2009 |
Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.
Topics: Actins; Adult; Angiotensin I; Angiotensin II; Animals; Bile Ducts; Cells, Cultured; Drug Evaluation, | 2009 |
[The effect of urokinase on hepatic fibrogenesis in rats].
Topics: Actins; Animals; Disease Models, Animal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver | 2009 |
Relationship between serum cytokines profiles and hepatic fibrosis in schistosomiasis mansoni: an experimental study.
Topics: Animals; Cytokines; Hydroxyproline; Interferon-gamma; Interleukin-4; Liver Cirrhosis, Experimental; | 2009 |
[Inhibitory effect of anluohuaxianwan on experimental hepatic fibrosis in rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethylnitrosamine; Drug Combinations; | 2010 |
[Therapeutic effect of Haobieyangyinruanjianfang on the mouse liver fibrosis caused by schistosomiasis].
Topics: Animals; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyaluronic Acid; | 2010 |
Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment.
Topics: Actins; Animals; Collagen; Cricetinae; Curcumin; Drug Administration Schedule; Gene Expression Regul | 2010 |
Preventive effects of a fractioned polysaccharide from a traditional Chinese herbal medical formula (Yu Ping Feng San) on carbon tetrachloride-induced hepatic fibrosis.
Topics: Animals; Apiaceae; Astragalus propinquus; Atractylodes; Carbon Tetrachloride Poisoning; Chemical and | 2010 |
Radiation-induced liver fibrosis is mitigated by gene therapy inhibiting transforming growth factor-β signaling in the rat.
Topics: Adenoviridae; Animals; Genetic Therapy; Genetic Vectors; Hepatic Stellate Cells; Hyaluronic Acid; Hy | 2010 |
N-methyl-4-isoleucine cyclosporine attenuates CCl -induced liver fibrosis in rats by interacting with cyclophilin B and D.
Topics: Actins; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Tet | 2011 |
Attenuated liver fibrosis after bile duct ligation and defective hepatic stellate cell activation in neural cell adhesion molecule knockout mice.
Topics: Actins; Animals; Blotting, Western; Carbon Tetrachloride; Cell Separation; Cells, Cultured; Cholesta | 2011 |
Icaritin induces cell death in activated hepatic stellate cells through mitochondrial activated apoptosis and ameliorates the development of liver fibrosis in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartate Aminotransferases | 2011 |
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap | 2011 |
[Therapeutic effect of indole-3-carbinol on pig serum-induced hepatic fibrosis in rats].
Topics: Actins; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Collagen; Curcumin; Enzyme Inhibi | 2011 |
[Uniform designed research on the active ingredients assembling of huangqi decoction for inhibition of DMN-induced liver fibrosis].
Topics: Alanine Transaminase; Animals; Dimethylnitrosamine; Drug Interactions; Drugs, Chinese Herbal; Hydrox | 2011 |
A standardized extract from Paeonia lactiflora and Astragalus membranaceus attenuates liver fibrosis induced by porcine serum in rats.
Topics: Animals; Astragalus propinquus; Becaplermin; Biomarkers; Cell Proliferation; Drugs, Chinese Herbal; | 2012 |
Trolox mitigates fibrosis in a bile duct ligation model.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Bile Ducts; Blotting, Western; Ch | 2013 |
The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation.
Topics: Actins; Animals; Betulinic Acid; Blotting, Western; Cell Line; Cell Survival; Hydroxyproline; Immuno | 2012 |
[Effects of blueberry on hepatic fibrosis and ultrastructural of hepatocytes in rats].
Topics: Alanine Transaminase; Animals; Blueberry Plants; Glutathione; Hepatocytes; Hydroxyproline; Liver; Li | 2012 |
[Effects of Chinese herbal medicine Xiaopi Pill in preventing rats from dimethylnitrosamine-induced liver fibrosis].
Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experim | 2012 |
CGX, a multiple herbal drug, improves cholestatic liver fibrosis in a bile duct ligation-induced rat model.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Catala | 2013 |
[Formula-syndrome correlation study of three classical anti-jaundice formulas in inhibition of liver fibrosis induced by dimethylnitrosamine in rats].
Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experim | 2012 |
Gadolinium chloride reverses dimethylnitrosamine (DMN)-induced rat liver fibrosis with increased matrix metalloproteinases (MMPs) of Kupffer cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Count; Cells, Cultured; Collagenases; Dimethylamines; Dose-R | 2003 |
The collagenolytic effects of the traditional Chinese medicine preparation, Han-Dan-Gan-Le, contribute to reversal of chemical-induced liver fibrosis in rats.
Topics: Animals; Astragalus propinquus; Carbon Tetrachloride; Collagen Type I; Drugs, Chinese Herbal; Hydrox | 2003 |
A trial on regeneration therapy of rat liver cirrhosis by controlled release of hepatocyte growth factor.
Topics: Animals; CHO Cells; Cricetinae; Hepatocyte Growth Factor; Humans; Hydrogels; Hydroxyproline; Injecti | 2003 |
Effect of Holotrichia diomphalia larvae on liver fibrosis and hepatotoxicity in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 2003 |
AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).
Topics: Animals; Base Sequence; Carbon Tetrachloride; DNA Primers; Enzyme-Linked Immunosorbent Assay; Hydrox | 2003 |
Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats.
Topics: Animals; Collagen Type I; Cysteine; Dietary Fats, Unsaturated; Dipeptides; Glutathione; Heme Oxygena | 2003 |
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine.
Topics: Administration, Oral; Alanine Transaminase; Alcohol Deterrents; Animals; Bilirubin; Cholestasis, Ext | 2003 |
Leptin receptor-deficient Zucker (fa/fa) rat retards the development of pig serum-induced liver fibrosis with Kupffer cell dysfunction.
Topics: Actins; Animals; Collagen Type I; Hydroxyproline; Kupffer Cells; Lipopolysaccharides; Liver Cirrhosi | 2003 |
[Studies on hormonal treatment of chronic liver diseases. Note VI. Action revealed by a prophlogistic hormone (STH) on the histological and histochemical picture and on the hexosamine and hydroxyproline content of the cirrhotic liver of the albino rat].
Topics: Amino Sugars; Animals; Growth Hormone; Hexosamines; Human Growth Hormone; Hydroxyproline; Liver Cirr | 1959 |
[Studies on the hormonal treatment of chronic liver diseases. Note V. Action of cortisone acetate on the histological and histochemical picture and on the hexosamine and hydroxyproline content of the cirrhotic liver (carbon tetrachloride-induced)].
Topics: Amino Sugars; Animals; Carbon Tetrachloride; Cortisone; Hexosamines; Hydroxyproline; Liver Cirrhosis | 1959 |
[CONTRIBUTION TO THE BIOCHEMISTRY OF AN EXPERIMENTAL LIVER CIRRHOSIS AND ON THE POSSIBILITY OF CONTROLLING IT PHARMACOLOGICALLY].
Topics: Animals; Biochemical Phenomena; Biochemistry; Collagen; Cortisone; Glycosaminoglycans; Hexosamines; | 1963 |
[EXPERIMENTAL LIVER CIRRHOSIS. 1. MORPHOLOGIC AND BIOCHEMICAL STUDY OF THE LIVER IN RATS FED ON DIETS DEFICIENT IN CHOLINE].
Topics: Animals; Biochemical Phenomena; Biochemistry; Choline; Deficiency Diseases; Diet; Hydroxyproline; Li | 1963 |
A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis.
Topics: Animals; Antioxidants; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, D | 2004 |
Sequential changes in redox status and nitric oxide synthases expression in the liver after bile duct ligation.
Topics: Animals; Bile Ducts, Extrahepatic; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydrox | 2004 |
Inhibitory effect of leflunomide on hepatic fibrosis induced by CCl4 in rats.
Topics: Adjuvants, Immunologic; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachlo | 2004 |
Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid.
Topics: Animals; Apoptosis; Farnesol; Gene Expression; Genes, ras; Hydroxyproline; In Situ Nick-End Labeling | 2004 |
[Pathological study of the therapeutic effect of wen-yang herbs on experimental liver cirrhosis].
Topics: Animals; Carbon Tetrachloride Poisoning; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhos | 2004 |
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis.
Topics: Animals; Chenodeoxycholic Acid; Cloning, Molecular; DNA-Binding Proteins; Hydroxyproline; Liver; Liv | 2004 |
Combination of interferon-beta and angiotensin-converting enzyme inhibitor, perindopril, attenuates the murine liver fibrosis development.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Antiviral Agents; Benzimidazoles; Biomark | 2005 |
Effects of a plasmid expressing antisense tissue inhibitor of metalloproteinase-1 on liver fibrosis in rats.
Topics: Animals; Antisense Elements (Genetics); Collagenases; Hydroxyproline; Liver; Liver Cirrhosis, Experi | 2005 |
Herbal medicine Rhei rhizome prevents liver fibrosis in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.
Topics: Actins; Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Choline Deficienc | 2005 |
Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis.
Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxypro | 2005 |
Melatonin ameliorates carbon tetrachloride-induced hepatic fibrogenesis in rats via inhibition of oxidative stress.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Glutathione Peroxi | 2005 |
[Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis].
Topics: Animals; Benzofurans; Collagen Type I; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, | 2005 |
[Proteomic analysis of proliferation and apoptosis in carbon tetrachloride induced rat liver fibrosis].
Topics: Animals; Apoptosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Caspase 12; Cell Prolifera | 2005 |
Morphological signs of cirrhosis regression. Experimental observations on carbon tetrachloride-induced liver cirrhosis of rats.
Topics: Animals; Biomarkers; Biopsy; Carbon Tetrachloride; Disease Models, Animal; Female; Fluorescent Antib | 2005 |
Rat liver fibrosis regresses better with pegylated interferon alpha2b and ursodeoxycholic acid treatments than spontaneous recovery.
Topics: Actins; Animals; Antiviral Agents; Apoptosis; Cholagogues and Choleretics; Collagenases; Drug Therap | 2006 |
[Experimental study of liver fibrosis reversal effect of warming-yang compound formula ganzhifu].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Collagen Type I; Collagen Type IV; Dr | 2006 |
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice.
Topics: Adenoviridae; Amino Acid Substitution; Animals; Apoptosis; Biomarkers; Carbon Tetrachloride Poisonin | 2006 |
[Dynamic change of metabolism related protein in liver tissue of rats' model of hepatic fibrosis and regulatory effect of fuzheng huayu decoction on it].
Topics: Animals; Carbon Tetrachloride; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experi | 2006 |
[Immune complex induced rat liver fibrosis model by intraperitoneal injection of human serum albumin].
Topics: Animals; Antigen-Antibody Complex; Disease Models, Animal; Fibrosis; Humans; Hyaluronic Acid; Hydrox | 2006 |
[Study on pathogenesis of CCl4 induced cirrhosis formation in rats based on the recipe used].
Topics: Animals; Carbon Tetrachloride; Diagnosis, Differential; Drugs, Chinese Herbal; Hydroxyproline; Liver | 2006 |
Mineralocorticoid receptor antagonist spironolactone prevents pig serum-induced hepatic fibrosis in rats.
Topics: Actins; Aldosterone; Animals; Cytochrome P-450 CYP11B2; Hydroxyproline; Kupffer Cells; Liver; Liver | 2006 |
Thalidomide in rat liver cirrhosis: blockade of tumor necrosis factor-alpha via inhibition of degradation of an inhibitor of nuclear factor-kappaB.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Down-Regul | 2006 |
How variable are hydroxyproline determinations made in different samples of the same liver?
Topics: Animals; Capillaria; Colorimetry; Enoplida Infections; Female; Hydroxyproline; Liver; Liver Cirrhosi | 2006 |
Effects of retinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice.
Topics: Animals; Collagen Type I; Disease Models, Animal; Gene Expression; Hydroxyproline; Liver Cirrhosis, | 2007 |
[Changes of mast cells and protease activated receptor-2 in experimental rat liver fibrosis].
Topics: Animals; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Mast Cells; Rats; Rats, Sprague | 2006 |
Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Culture | 2006 |
[Inhibitory effects of silymarin on hepatic fibrosis induced by dimethylnitrosamine: experiment with rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Dimethylnitrosamine; Hydroxyp | 2006 |
[Effect of Fuzheng Jiangan formula on liver fibrosis induced by albumin in rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Collagen Type IV; Drugs, Chinese Herbal; | 2006 |
Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Capillaria; Chronic Disease; Disease Models, Anim | 2006 |
[Experimental study of two histological quantitative methods of hepatic fibrosis].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drugs, Chinese Herbal; Female; Hydrox | 2007 |
Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions.
Topics: Administration, Oral; Alanine; Animals; Atorvastatin; Carbon Tetrachloride; Collagen; Deuterium Oxid | 2007 |
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cell Proliferation; | 2007 |
Prevention of liver cirrhosis in rats by curcumin.
Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Collagen T | 2007 |
[Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats].
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Ducts; Captopril; Fibrosis; Hydroxypr | 2007 |
Tetrandrine stimulates the apoptosis of hepatic stellate cells and ameliorates development of fibrosis in a thioacetamide rat model.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzylisoquinolines; Caspase 3; Ex | 2007 |
Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Collagen; Disease Mod | 2007 |
A fermented substance from Aspergillus phoenicis reduces liver fibrosis induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspergillus; Carbon Tetrachloride; Colla | 2007 |
Therapeutic potential of bone marrow-derived mesenchymal stem cells on experimental liver fibrosis.
Topics: Actins; Animals; Bone Marrow Cells; Cell- and Tissue-Based Therapy; Collagen; Female; Gene Expressio | 2007 |
Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Astragalus Plant; Carbon Tetrachloride; | 2007 |
Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis.
Topics: Actins; Animals; Apoptosis; Drug Therapy, Combination; Hepatocytes; Hydroxyproline; Interferon alpha | 2007 |
Interferon-beta reduces the mouse liver fibrosis induced by repeated administration of concanavalin A via the direct and indirect effects.
Topics: Animals; Collagen; Collagen Type I; Concanavalin A; Cytokines; Disease Progression; Drug Evaluation, | 2007 |
A novel synthetic oleanolic acid derivative (CPU-II2) attenuates liver fibrosis in mice through regulating the function of hepatic stellate cells.
Topics: Actins; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Line; Cell Survival; Col | 2008 |
Nitric oxide-independent activation of soluble guanylate cyclase by BAY 60-2770 in experimental liver fibrosis.
Topics: Animals; Benzoates; Biphenyl Compounds; Blood Pressure; Carbon Tetrachloride Poisoning; Chemical and | 2008 |
Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats.
Topics: Animals; Glucuronidase; Hydroxyproline; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Pip | 2008 |
Coagulation status modulates murine hepatic fibrogenesis: implications for the development of novel therapies.
Topics: Actins; Animals; Anticoagulants; Carbon Tetrachloride; Factor V; Gene Expression; Hydroxyproline; Li | 2008 |
[CCI4 - induced liver cirrhosis, in the rar: effects of colchicine in its induction and recovery].
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Colchicine; Collagen; Hydroxyproline; Liver; L | 1981 |
Carbon tetrachloride-induced hepatic fibrosis and cirrhosis in the developing rat: an experimental model of cirrhosis in childhood.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 1983 |
[Metabolism of halothane in rats with CCl4-alcohol-induced liver fibrosis].
Topics: Animals; Biotransformation; Carbon Tetrachloride Poisoning; Halothane; Hydroxyproline; Kinetics; Liv | 1983 |
[Effect of malotilate (diisopropyl 1, 3-dithiol-2-ylidenemalonate) on chronic liver injury caused by carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hydroxyproline; Liver; Liver Cirrhosi | 1982 |
Liver proline oxidase activity and collagen synthesis in rats with cirrhosis induced by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride Poisoning; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Experimen | 1980 |
Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium.
Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Feces; gamma-Glutamyltransferase; Hydroxyproline; Ib | 1995 |
Experimental liver cirrhosis induced by alcohol and iron.
Topics: Animals; Collagen; Hydroxyproline; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis, Alcoholic; Live | 1995 |
Beta-carotene (provitamin A) decreases the severity of CCl4-induced hepatic inflammation and fibrosis in rats.
Topics: Animals; beta Carotene; Carbon Tetrachloride Poisoning; Carotenoids; Chemical and Drug Induced Liver | 1995 |
[Effects of nifedipine on hepatic hyaluronic acid, hydroxyproline and glucosaminidase contents in rats with liver fibrosis].
Topics: Acetylglucosaminidase; Animals; Carbon Tetrachloride Poisoning; Dose-Response Relationship, Drug; Hy | 1994 |
Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.
Topics: Amino Acids; Animals; Choline Deficiency; Diet; Disease Models, Animal; Glutathione Transferase; Hyd | 1994 |
Detection of liver fibrosis with magnetic cross-relaxation.
Topics: Animals; Body Water; Carbon Tetrachloride; Hydroxyproline; Image Enhancement; Liver; Liver Cirrhosis | 1994 |
Serum collagenase activity reflects the amount of liver collagenase in chronic carbon tetrachloride-treated rats.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Collagenases; Hydroxyproline; Injections, Subc | 1994 |
Role of hepatic vitamin A and lipocyte distribution in experimental hepatic fibrosis.
Topics: Animals; Carbon Tetrachloride; Collagen; Diterpenes; Hydroxyproline; Liver; Liver Cirrhosis, Experim | 1993 |
Vitamin A deficiency potentiates carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Carbon Tetrachloride; Collagen; Female; Hydroxyproline; Liver; Liver Cirrhosis, Experimenta | 1994 |
Radiation hepatology of the rat: association of the production of prostacyclin with radiation-induced hepatic fibrosis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspartate Aminotransferases; Cesium Radioisotopes; Dose-Respo | 1996 |
Effects of hepatic stimulator substance, herbal medicine, selenium/vitamin E, and ciprofloxacin on cirrhosis in the rat.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Drugs, Chinese Herbal; Gro | 1996 |
The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet.
Topics: Amino Acids; Animals; Choline Deficiency; Gene Expression; Hydroxyproline; Liver; Liver Cirrhosis, E | 1996 |
Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis.
Topics: Animals; Cholestasis; Disease Models, Animal; Female; Humans; Hydroxyproline; Liver Cirrhosis, Exper | 1996 |
Schistosoma mansoni: relationship of tumor necrosis factor-alpha to morbidity and collagen deposition in chronic experimental infection.
Topics: Acute Disease; Animals; Blotting, Northern; Chronic Disease; Collagen; Hematocrit; Hydroxyproline; L | 1996 |
Antioxidative effect of prostaglandin E2 in thioacetamide-induced liver cirrhosis.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Antioxidants; Carcinogens; Cells, Cultured; Dinoprostone; Fa | 1997 |
Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction.
Topics: Animals; Basidiomycota; Body Weight; Cholestasis; Common Bile Duct Diseases; Female; Glycyrrhetinic | 1997 |
Low doses of insulin-like growth factor-I improve nitrogen retention and food efficiency in rats with early cirrhosis.
Topics: Acute Disease; Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Feces; Hydroxyproline; | 1997 |
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Dimet | 1997 |
Prolyl 4-hydroxylase inhibitor (HOE 077) inhibits pig serum-induced rat liver fibrosis by preventing stellate cell activation.
Topics: Animals; Biomarkers; Blood; Blotting, Northern; Enzyme Inhibitors; Hydroxyproline; Liver; Liver Cirr | 1997 |
Histological and biochemical changes induced by total bile duct ligation in the rat.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Female | 1997 |
Herbal medicine Sho-saiko-to (TJ-9) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.
Topics: Amino Acids; Animals; Antineoplastic Agents; Biomarkers; Cell Division; Choline Deficiency; Diet; Dr | 1998 |
Interferon gamma treatment prevents procollagen gene expression without affecting transforming growth factor-beta1 expression in pig serum-induced rat liver fibrosis in vivo.
Topics: Animals; Antiviral Agents; Biomarkers; Blotting, Northern; Dose-Response Relationship, Drug; Gene Ex | 1998 |
Effects of the deleted form of hepatocyte growth factor on serum hyaluronate levels in rats with liver cirrhosis.
Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatocyte Growth Factor; Humans; Hyaluronic Aci | 1998 |
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagenases; Gene | 1998 |
Fibrosis accelerates the development of enzyme-altered lesions in the rat liver.
Topics: Actins; Amino Acids; Animals; Blood; Choline; Diet; Glutathione Transferase; Hydroxyproline; Liver; | 1998 |
Antifibrotic and hemodynamic effects of the early and chronic administration of octreotide in two models of liver fibrosis in rats.
Topics: Animals; Body Weight; Fibronectins; Fibrosis; Hemodynamics; Hyaluronic Acid; Hydroxyproline; Liver; | 1998 |
Increase of mast cells in the liver and lung may be associated with but not a cause of fibrosis: demonstration using mast cell-deficient Ws/Ws rats.
Topics: Animals; Cell Count; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lung; Male; Mast Cells; P | 1998 |
Enzyme-linked immunosorbent assay for serum procollagen type III peptide in rats with hepatic fibrosis.
Topics: Animals; Bile Ducts; Biomarkers; Dimethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Hydroxyprol | 1998 |
Chronic blockade of endothelin receptors in cirrhotic rats: hepatic and hemodynamic effects.
Topics: Animals; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hydroxyproline; Hypertension, P | 1999 |
Long-term administration of PGE1 increases liver fibrosis and collateral blood flow in bile-duct-ligated rats.
Topics: Animals; Bile Ducts; Blood Flow Velocity; Collateral Circulation; Hemodynamics; Hyaluronic Acid; Hyd | 1999 |
Evaluation of role of mast cells in the development of liver fibrosis using mast cell-deficient rats and mice.
Topics: Animals; Bile Ducts; Blood; Carbon Tetrachloride; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, | 1999 |
Inhibition of hepatic cell nuclear DNA fragmentation by zinc in carbon tetrachloride-treated rats.
Topics: Animals; Carbon Tetrachloride; DNA Fragmentation; Hydroxyproline; Liver; Liver Cirrhosis, Experiment | 1999 |
Dimethylnitrosamine-induced hepatic cirrhosis: a new canine model of an ancient human disease.
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Female; Humans; Hydroxyproline; Liver; L | 1970 |
Effects of Sho-saiko-to extract on liver fibrosis in relation to the changes in hydroxyproline and retinoid levels of the liver in rats.
Topics: Administration, Oral; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drugs, Chinese | 1999 |
Characterization of hepatic iron overload following dietary administration of dicyclopentadienyl iron (Ferrocene) to mice: cellular, biochemical, and molecular aspects.
Topics: Alanine Transaminase; Animals; Blotting, Northern; Blotting, Western; Body Weight; Ferritins; Ferrou | 2000 |
Hepatic fibrogenesis using chronic arsenic ingestion: studies in a murine model.
Topics: Animals; Arsenic; Collagen; Disease Models, Animal; Hydroxyproline; Liver Cirrhosis, Experimental; M | 1999 |
Antifibrotic effects of the methanol extract of Polygonum aviculare in fibrotic rats induced by bile duct ligation and scission.
Topics: Animals; Artemisia; Bile Ducts; Body Weight; China; Hydroxyproline; Korea; Ligation; Liver; Liver Ci | 2000 |
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Ascites; Aspartate Aminot | 2000 |
Hepatoprotective activity of Emblica officinalis and Chyavanaprash.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Collagen; Hydroxypr | 2000 |
S-adenosylmethionine prevents hepatic tocopherol depletion in carbon tetrachloride-injured rats.
Topics: Animals; Antioxidants; Ascorbic Acid Deficiency; Carbon Tetrachloride Poisoning; Glutathione; Hydrox | 2000 |
Antifibrotic effect of Stephania tetrandra on experimental liver fibrosis induced by bile duct ligation and scission in rats.
Topics: Animals; Bile Ducts; Body Weight; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Ma | 2000 |
Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model.
Topics: Animals; Capillaria; Case-Control Studies; Disease Models, Animal; Female; Hydroxyproline; Immunolog | 2001 |
[Changes of lipid peroxidation in liver fibrogenesis induced by dimethylnitrosamine and drugs' intervention].
Topics: Animals; Dimethylnitrosamine; Hydroxyproline; Interferon-gamma; Lipid Peroxidation; Liver Cirrhosis, | 2001 |
[Experimental study of dahuang zhechong pills in the treatment of immunological liver fibrosis in rats].
Topics: Animals; Collagen; Drugs, Chinese Herbal; Female; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirr | 1998 |
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
Topics: Administration, Oral; Animals; Cholestasis; Chronic Disease; Collagen; Cytokines; DNA Probes; DNA, C | 2002 |
Tetrandrine prevents tissue inhibitor of metalloproteinase-1 messenger RNA expression in rat liver fibrosis.
Topics: Alanine Transaminase; Alkaline Phosphatase; Alkaloids; Animals; Aspartate Aminotransferases; Benzyli | 2001 |
Effects of salviainolic acid A (SA-A) on liver injury: SA-A action on hepatic peroxidation.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Cells, Cultured; Dose-Res | 2001 |
Scutellaria baicalensis inhibits liver fibrosis induced by bile duct ligation or carbon tetrachloride in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Carbo | 2002 |
Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni.
Topics: Animals; Collagen; Disease Models, Animal; Granuloma; Hydroxyproline; Immunohistochemistry; Leptin; | 2002 |
Biochemical and immunochemical study of lysyl oxidase in experimental hepatic fibrosis in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Carbon Tetrachloride Poisoning; Collagen; Fluorescent Antibody | 1978 |
Hepatic prolyl hydroxylase activity in experimental cirrhosis.
Topics: Carbon Tetrachloride Poisoning; Coenzymes; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Experim | 1975 |
[Action of carbon tetrachloride on the quality of hepatic collagen].
Topics: Aging; Animals; Carbon Tetrachloride Poisoning; Collagen; Female; Granuloma; Hydroxyproline; Liver; | 1975 |
Effect of long-term administration of ethanol to the rat: lipids, collagen and other proteins, and Mallory bodies in the liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Collagen; Diet; End | 1975 |
Changes in the markers related to collagen synthesis in the liver of chronically alcohol treated rats.
Topics: Animals; Collagen; Desmin; Ethanol; Hydroxyproline; Immunoenzyme Techniques; Laminin; Liver; Liver C | 1992 |
Dependence of ultrasonic attenuation of liver on pathologic fat and fibrosis: examination with experimental fatty liver and liver fibrosis models.
Topics: Adipose Tissue; Animals; Body Water; Collagen; Disease Models, Animal; Fatty Liver; Hydroxyproline; | 1992 |
Collagenolytic cathepsin B and L activity in experimental fibrotic liver and human liver.
Topics: Animals; Carbon Tetrachloride; Cathepsin B; Cathepsin H; Cathepsin L; Cathepsins; Collagen; Cysteine | 1992 |
Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop
Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Collagen; Dimethylnitrosamine; Female; Fibrosis | 1992 |
Effect of acute phase proteins, especially alpha 2-macroglobulin, on granuloma formation around Schistosoma mansoni eggs in the rat.
Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Collagen; Granuloma; Host-Parasite Interactions | 1991 |
Effects of KF-14363 on liver fibrosis in rats with chronic liver injury induced by carbon tetrachloride.
Topics: Alkaline Phosphatase; Animals; Benzazepines; Carbon Tetrachloride; Chronic Disease; Hydroxyproline; | 1991 |
Minor contribution of hepatocytes to collagen production in normal and early fibrotic rat livers.
Topics: Amino Acids; Animals; Carbon Tetrachloride; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver; Li | 1991 |
Regulation of collagen production in freshly isolated cell populations from normal and cirrhotic rat liver: effect of lactate.
Topics: Animals; Cells, Cultured; Collagen; Hydroxyproline; Lactates; Liver; Liver Cirrhosis, Experimental; | 1991 |
Inhibitory effect of acyclic retinoid (polyprenoic acid) on hepatic fibrosis in CCl4-treated rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Hydroxyp | 1990 |
Collagenase and collagenolytic cathepsin in normal and fibrotic rat liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Cathepsins; Electrophoresis, Polyacrylamide Gel; Hydroxypro | 1990 |
Effect of sensory denervation with capsaicin on liver fibrosis induced by common bile duct ligation in rat.
Topics: Animals; Capsaicin; Collagen; Common Bile Duct; Denervation; Desmin; Fluorescent Antibody Technique; | 1990 |
Methylcellulose prevents the regression of carbon tetrachloride-induced liver fibrosis and cirrhosis in rats.
Topics: Animals; Carbon Tetrachloride; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; | 1990 |
Active and latent collagenase activity during reversal of hepatic fibrosis in murine schistosomiasis.
Topics: Animals; Female; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Mice; Microbial Collagenase; | 1989 |
The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Body Weight; Collagen; Deficiency Diseases; Disease Models, | 1989 |
Lactate and pyruvate increase the incorporation of [3H]proline into collagen [3H]hydroxyproline in liver slices of CCl4 cirrhotic rats.
Topics: Animals; Carbon Tetrachloride; Collagen; Cyclic AMP; Hydroxyproline; Lactates; Lactic Acid; Liver; L | 1987 |
Collagenolytic activity in experimental cirrhosis of the liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Collagen; Hydroxyproline; Liver Cirrhosis, Experimental; Ma | 1987 |
Free and small peptide-bound [14C]hydroxyproline synthesis in rat liver in vitro in CCl4-induced hepatic fibrosis.
Topics: Animals; Carbon Tetrachloride Poisoning; Cathepsins; Hydroxyproline; Liver Cirrhosis, Experimental; | 1988 |
Anti-fibrotic effect of malotilate on liver fibrosis induced by carbon tetrachloride in rats.
Topics: Animals; Carbon Tetrachloride; Collagen; Hydroxyproline; Liver Cirrhosis, Experimental; Male; Malona | 1986 |
[Effects of anticancer drugs on hepatic fibrosis in the rats with carbon tetrachloride-induced hepatic injury].
Topics: Animals; Antineoplastic Agents; Carbon Tetrachloride Poisoning; Hydroxyproline; Liver; Liver Cirrhos | 1987 |
Acute phase reactants enhance CCl4 induced liver cirrhosis in the rat.
Topics: Alanine Transaminase; Animals; C-Reactive Protein; Carbon Tetrachloride; Drug Synergism; Glutamate D | 1986 |
Drug metabolizing activity in rats with chronic liver injury induced by carbon tetrachloride: relationship with the content of hydroxyproline in the liver.
Topics: Animals; Biotransformation; Carbon Tetrachloride Poisoning; Cytochrome b Group; Cytochrome P-450 Enz | 1986 |
Increased procollagen mRNA levels in carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; DNA; Hydroxyproline; Liver; Liver Cirrhosis, E | 1987 |
[Significance of determination of some biochemical indices in hepatic fibrosis of animal schistosomiasis japonica].
Topics: Animals; Hydroxyproline; Liver Cirrhosis, Experimental; Monoamine Oxidase; Mucoproteins; Praziquante | 1985 |
Correlation of structural and functional recovery from cirrhosis in rats treated with lipotropic diets.
Topics: Animals; Autoradiography; Choline; Choline Deficiency; Dietary Fats; Dietary Proteins; DNA; Histocyt | 1966 |
A new experimental approach in the study of chronic alcoholism. IV. Reproduction of alcoholic cirrhosis in rats and the role of lipotropes versus vitamins.
Topics: Alcoholism; Animals; Cholesterol; Chronic Disease; Collagen; Dietary Proteins; DNA; Fatty Liver; Hum | 1969 |
[The influence of cortisone on proliferation and metabolism of the connective tissue in the experimental cirrhosis of the liver].
Topics: Acetates; Amides; Animals; Carbon Tetrachloride; Connective Tissue; Glucosamine; Glycosaminoglycans; | 1969 |
[The effect of pyridinolcarbamate on the synthesis of glycosaminoglycans and collagen in connective tissue in experimental induced liver cirrhosis in rats (author's transl)].
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chromat | 1974 |
Increased protocollagen hydroxylase activity in the livers of rats with hepatic fibrosis.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Hydroxyproline; Liver; Liver Cirrhosis, Ex | 1967 |
Proceedings: Recent developments in the pathogenesis of hepatic cirrhosis.
Topics: Animals; Cells, Cultured; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lysosomes; Mice | 1974 |
The effects of azathioprine on CCl4 induced cirrhosis in the rat.
Topics: Adenosine Triphosphate; Animals; Azathioprine; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; | 1974 |
Turnover of hepatic collagen in reversible and irreversible fibrosis.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Collagen; DNA; Female; Glycine; Hydroxypro | 1970 |
Rate of urea synthesis in normal and cirrhotic rat liver with reference to the arginine synthetase system.
Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Blood Proteins; Blood Urea Nitrogen; Diet; Hydroxypro | 1970 |
[Urinary excretion of hydroxyproline in dietetic cirrhosis in rats].
Topics: Age Factors; Animals; Body Weight; Choline Deficiency; Collagen; Hydroxyproline; Liver; Liver Cirrho | 1967 |
[Experimental liver cirrhosis. Transaminase activity, collagen deposit and cell proliferation in the rat with dietetic cirrhosis].
Topics: Animals; Aspartate Aminotransferases; Choline Deficiency; Collagen; Hydroxyproline; Liver Cirrhosis, | 1967 |
Collagen biosynthesis in normal and cirrhotic rat liver slices.
Topics: Animals; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Collagen; Hydroxyproline; Liv | 1969 |
Protocollagen proline hydroxylase in normal liver and in hepatic fibrosis.
Topics: Aged; Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chick Embryo; Collagen; Female; Huma | 1969 |