hydroxyproline has been researched along with Chronic Lung Injury in 29 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Paraquat (PQ) induces pulmonary fibrosis, a progressive lung disorder resulting in severe respiratory failure and death." | 7.91 | Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice. ( Khodayar, MJ; Mansouri, E; Mirzaee, S; Shirani, M; Zeinvand-Lorestani, M, 2019) |
| "In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice." | 7.88 | Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression. ( Ghazi-Khansari, M; Heidari, MR; Iranpour, M; Mandegary, A; Pourgholamhossein, F; Pourgholi, L; Pournamdari, M; Poursalehi, HR; Rasooli, R; Samareh-Fekri, M, 2018) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 7.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| "Paraquat (PQ) induces pulmonary fibrosis, a progressive lung disorder resulting in severe respiratory failure and death." | 3.91 | Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice. ( Khodayar, MJ; Mansouri, E; Mirzaee, S; Shirani, M; Zeinvand-Lorestani, M, 2019) |
| "In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice." | 3.88 | Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression. ( Ghazi-Khansari, M; Heidari, MR; Iranpour, M; Mandegary, A; Pourgholamhossein, F; Pourgholi, L; Pournamdari, M; Poursalehi, HR; Rasooli, R; Samareh-Fekri, M, 2018) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 3.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| "Hydroxyproline does not seem to be a suitable marker for this purpose." | 1.56 | Do oral amino acid supplements facilitate the healing of rat lung injuries? ( Ağababaoğlu, İ; Aksun, S; Çakır, E; Ersöz, H; Güneli, E; Taylan, İ, 2020) |
| "The effect of MSC transplantation on lung injury was then evaluated 180 days after transplantation." | 1.48 | Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury. ( Dai, J; Dai, X; Fang, J; Feng, C; Hao, J; Hao, Y; Li, J; Li, R; Liu, J; Lu, B; Ma, R; Qiao, Z; Ran, Y; Xiong, W; Zhang, J; Zhou, Q, 2018) |
| "Idiopathic pulmonary fibrosis is a progressive, fatal disease with limited treatment options." | 1.43 | Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis. ( Habgood, AN; Jenkins, G; John, AE; Johnson, SR; Laurent, GJ; Porte, J; Tatler, AL; Wahl, SM, 2016) |
| "Successful recovery from lung injury requires the repair and regeneration of alveolar epithelial cells to restore the integrity of gas-exchanging regions within the lung and preserve organ function." | 1.43 | Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. ( Chen, H; Geng, Y; Jiang, D; Kurkciyan, A; Liang, J; Liu, N; Mena, JM; Noble, PW; Stripp, BR; Xie, T; Zhang, Y, 2016) |
| "Thalidomide has been used in inflammatory and autoimmune disorders due to its anti-inflammatory activity." | 1.39 | Anti-inflammatory effect of thalidomide in paraquat-induced pulmonary injury in mice. ( Amirshahrokhi, K, 2013) |
| "Radiation-induced lung injury is one of the limiting factors for radiation therapy." | 1.38 | Protective effect of recombinant protein SOD-TAT on radiation-induced lung injury in mice. ( He, H; Hou, X; Liu, S; Pan, J; Rao, P; Su, Y; Wu, J, 2012) |
| "Quercetin was administered to the rats daily for 14 days after PQ instillation." | 1.36 | Protective effect of quercetin against paraquat-induced lung injury in rats. ( Kim, SJ; Kim, YC; Kwon, DY; Park, HK; Park, JH, 2010) |
| "Clinical use of GGA for drug-induced pulmonary fibrosis might be considered in the future." | 1.35 | Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model. ( Fujibayashi, T; Hasegawa, Y; Hashimoto, N; Ishiguro, N; Jijiwa, M; Kojima, T, 2009) |
| "Lung hydroxyproline content was increased in hyperoxia-exposed wild-type, but not in cat S-deficient lungs." | 1.34 | Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury. ( Bingol-Karakoc, G; Cataltepe, S; Hirakawa, H; Karaaslan, C; Mariani, TJ; Pierce, RA; Saad, A; Shapiro, SD; Shi, GP; Starcher, B; Weber, E; Weng, M, 2007) |
| "IL-18-/- mice showed much worse lung injuries than wild-type mice, as assessed by the survival rate, histological images, and leukocyte infiltration in the bronchoalveolar lavage fluid and myeloperoxidase activity." | 1.33 | Protection against bleomycin-induced lung injury by IL-18 in mice. ( Adachi, S; Fujita, Y; Kashiwamura, S; Kubota, A; Nakatani-Okuda, A; Okamura, H; Sekiyama, A; Tanizawa, T; Tsuji, Y; Ueda, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.34) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 15 (51.72) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, CF | 1 |
| Wilson, CL | 1 |
| Chow, YH | 1 |
| Liles, WC | 1 |
| Gharib, SA | 1 |
| Altemeier, WA | 1 |
| Schnapp, LM | 1 |
| Mirzaee, S | 1 |
| Mansouri, E | 1 |
| Shirani, M | 1 |
| Zeinvand-Lorestani, M | 1 |
| Khodayar, MJ | 1 |
| Ersöz, H | 1 |
| Ağababaoğlu, İ | 1 |
| Taylan, İ | 1 |
| Çakır, E | 1 |
| Aksun, S | 1 |
| Güneli, E | 1 |
| Ho, HL | 1 |
| Huo, TI | 1 |
| Chang, T | 1 |
| Lee, WS | 1 |
| Hsin, IF | 1 |
| Lee, FY | 1 |
| Huang, HC | 1 |
| Hou, MC | 1 |
| Lee, SD | 1 |
| Pourgholamhossein, F | 1 |
| Rasooli, R | 1 |
| Pournamdari, M | 1 |
| Pourgholi, L | 1 |
| Samareh-Fekri, M | 1 |
| Ghazi-Khansari, M | 1 |
| Iranpour, M | 1 |
| Poursalehi, HR | 1 |
| Heidari, MR | 1 |
| Mandegary, A | 1 |
| Hao, Y | 1 |
| Ran, Y | 1 |
| Lu, B | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Feng, C | 1 |
| Fang, J | 1 |
| Ma, R | 1 |
| Qiao, Z | 1 |
| Dai, X | 1 |
| Xiong, W | 1 |
| Liu, J | 1 |
| Zhou, Q | 1 |
| Hao, J | 1 |
| Li, R | 1 |
| Dai, J | 1 |
| Amirshahrokhi, K | 1 |
| Yao, L | 1 |
| Liu, CJ | 1 |
| Luo, Q | 1 |
| Gong, M | 1 |
| Chen, J | 1 |
| Wang, LJ | 1 |
| Huang, Y | 1 |
| Jiang, X | 1 |
| Xu, F | 1 |
| Li, TY | 1 |
| Shu, C | 1 |
| Wang, YY | 1 |
| Zhang, CY | 1 |
| Ma, YQ | 1 |
| He, ZX | 1 |
| Zhe, H | 1 |
| Zhou, SF | 1 |
| Habgood, AN | 1 |
| Tatler, AL | 1 |
| Porte, J | 1 |
| Wahl, SM | 1 |
| Laurent, GJ | 1 |
| John, AE | 1 |
| Johnson, SR | 1 |
| Jenkins, G | 1 |
| Liang, J | 1 |
| Zhang, Y | 2 |
| Xie, T | 1 |
| Liu, N | 1 |
| Chen, H | 1 |
| Geng, Y | 1 |
| Kurkciyan, A | 1 |
| Mena, JM | 1 |
| Stripp, BR | 1 |
| Jiang, D | 1 |
| Noble, PW | 1 |
| Kadry, MO | 1 |
| Abdel-Megeed, RM | 1 |
| Bao, P | 1 |
| Gao, W | 1 |
| Li, S | 1 |
| Zhang, L | 1 |
| Qu, S | 1 |
| Wu, C | 1 |
| Qi, H | 1 |
| Fujibayashi, T | 1 |
| Hashimoto, N | 1 |
| Jijiwa, M | 1 |
| Hasegawa, Y | 1 |
| Kojima, T | 1 |
| Ishiguro, N | 1 |
| Park, HK | 1 |
| Kim, SJ | 1 |
| Kwon, DY | 1 |
| Park, JH | 1 |
| Kim, YC | 1 |
| Adachi, K | 1 |
| Mizoguchi, K | 1 |
| Kawarada, S | 1 |
| Miyoshi, A | 1 |
| Suzuki, M | 1 |
| Chiba, S | 1 |
| Deki, T | 1 |
| Zhi, Q | 1 |
| Sun, H | 1 |
| Qian, X | 1 |
| Yang, L | 1 |
| McGrath, EE | 1 |
| Lawrie, A | 1 |
| Marriott, HM | 1 |
| Mercer, P | 1 |
| Cross, SS | 1 |
| Arnold, N | 1 |
| Singleton, V | 1 |
| Thompson, AA | 1 |
| Walmsley, SR | 1 |
| Renshaw, SA | 1 |
| Sabroe, I | 1 |
| Chambers, RC | 1 |
| Dockrell, DH | 1 |
| Whyte, MK | 1 |
| Pan, J | 1 |
| Su, Y | 1 |
| Hou, X | 1 |
| He, H | 1 |
| Liu, S | 1 |
| Wu, J | 1 |
| Rao, P | 1 |
| Vujaskovic, Z | 1 |
| Batinic-Haberle, I | 1 |
| Rabbani, ZN | 1 |
| Feng, QF | 1 |
| Kang, SK | 1 |
| Spasojevic, I | 1 |
| Samulski, TV | 1 |
| Fridovich, I | 1 |
| Dewhirst, MW | 1 |
| Anscher, MS | 1 |
| Staversky, RJ | 1 |
| Watkins, RH | 1 |
| Wright, TW | 1 |
| Hernady, E | 1 |
| LoMonaco, MB | 1 |
| D'Angio, CT | 1 |
| Williams, JP | 1 |
| Maniscalco, WM | 1 |
| O'Reilly, MA | 1 |
| Nakatani-Okuda, A | 1 |
| Ueda, H | 1 |
| Kashiwamura, S | 1 |
| Sekiyama, A | 1 |
| Kubota, A | 1 |
| Fujita, Y | 1 |
| Adachi, S | 1 |
| Tsuji, Y | 1 |
| Tanizawa, T | 1 |
| Okamura, H | 1 |
| Huang, SY | 1 |
| Song, LW | 1 |
| Liu, T | 1 |
| Wang, QM | 1 |
| Li, Y | 1 |
| Sun, L | 1 |
| Fattman, CL | 1 |
| Tan, RJ | 1 |
| Tobolewski, JM | 1 |
| Oury, TD | 1 |
| Hirakawa, H | 1 |
| Pierce, RA | 1 |
| Bingol-Karakoc, G | 1 |
| Karaaslan, C | 1 |
| Weng, M | 1 |
| Shi, GP | 1 |
| Saad, A | 1 |
| Weber, E | 1 |
| Mariani, TJ | 1 |
| Starcher, B | 1 |
| Shapiro, SD | 1 |
| Cataltepe, S | 1 |
| Nario, RC | 1 |
| Hubbard, AK | 1 |
| Adamson, IY | 1 |
| King, GM | 1 |
| Bowden, DH | 1 |
| Dubaybo, BA | 1 |
| Thet, LA | 1 |
| Taylor, RG | 1 |
| McCall, CE | 1 |
| Thrall, RS | 1 |
| Woodruff, RD | 1 |
| O'Flaherty, JT | 1 |
29 other studies available for hydroxyproline and Chronic Lung Injury
| Article | Year |
|---|---|
Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Lung; Lung Injury; Mice; Mice, Inb | 2022 |
Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice.
Topics: Animals; Antioxidants; Diosmin; Fibrosis; Glutathione; Hydroxyproline; Lung Injury; Male; Mice; Mice | 2019 |
Do oral amino acid supplements facilitate the healing of rat lung injuries?
Topics: Animals; Arginine; Female; Glutamine; Hydroxyproline; Lung Injury; Rats; Wound Healing | 2020 |
Ascorbate lacks significant influence in rats with bile duct ligation-induced liver injury.
Topics: Animals; Ascorbic Acid; Bile Ducts; Body Weight; Hydroxyproline; Ligation; Liver Cirrhosis, Experime | 2017 |
Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bronchoalveolar Lavage Fluid; Fibrosi | 2018 |
Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Flow C | 2018 |
Anti-inflammatory effect of thalidomide in paraquat-induced pulmonary injury in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Hydroxyproline; Immunohistochemistry; I | 2013 |
Protection against hyperoxia-induced lung fibrosis by KGF-induced MSCs mobilization in neonatal rats.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Transplantation; Female; Fibroblast Growth F | 2013 |
Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen; Cytokines; Cytoprotection | 2015 |
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen; Gene Deletion; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Lu | 2016 |
Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.
Topics: Alveolar Epithelial Cells; Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Line; Cell Prolifer | 2016 |
Bone marrow-derived mesenchymal stem cells mitigate caspase-3 and 8-hydroxy proline induced via β-adrenergic agonist in pulmonary injured rats.
Topics: Adrenergic beta-2 Receptor Agonists; Allografts; Animals; Biomarkers; Bone Marrow Cells; Caspase 3; | 2017 |
Effect of pretreatment with high-dose ulinastatin in preventing radiation-induced pulmonary injury in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Gene Expression Reg | 2009 |
Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid | 2009 |
Protective effect of quercetin against paraquat-induced lung injury in rats.
Topics: Animals; Antioxidants; Collagen; Fibroblasts; Gene Expression Regulation; Glutathione; Heme Oxygenas | 2010 |
Effects of erlotinib on lung injury induced by intratracheal administration of bleomycin (BLM) in rats.
Topics: Animals; Bleomycin; Dogs; Erlotinib Hydrochloride; Humans; Hydroxyproline; Injections; Lung; Lung In | 2010 |
Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat?
Topics: Animals; Antidotes; Antipyrine; Bronchoalveolar Lavage Fluid; Edaravone; Herbicides; Hydroxyproline; | 2011 |
Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis.
Topics: Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage; Case-Control Studies; Collagen; Enzyme-Linke | 2012 |
Protective effect of recombinant protein SOD-TAT on radiation-induced lung injury in mice.
Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Humans; Hydroxyproline; Lung Injury; Mic | 2012 |
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
Topics: Animals; Antioxidants; Collagen; Female; Fibrosis; Free Radicals; Hydroxyproline; Immunohistochemist | 2002 |
Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1).
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin- | 2002 |
Protection against bleomycin-induced lung injury by IL-18 in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Granulocyte-M | 2005 |
[The protective effect of recombinant Chinese interferon-gamma in pulmonary injury in mice].
Topics: Animals; Bleomycin; Collagen Type I; Collagen Type III; Disease Models, Animal; Humans; Hydroxyproli | 2005 |
Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase.
Topics: Animals; Asbestos, Crocidolite; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lu | 2006 |
Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Bronchopulmonary Dysplasia; Cathepsins; Col | 2007 |
Silica exposure increases expression of pulmonary intercellular adhesion molecule-1 (ICAM-1) in C57Bl/6 mice.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Collagen; Dose- | 1996 |
Collagen breakdown during acute lung injury.
Topics: Acute Disease; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; E | 1988 |
Changes in lung tissue and lavage fibronectin after paraquat injury in rats.
Topics: Albumins; Animals; Fibronectins; Hydroxyproline; Lung; Lung Injury; Paraquat; Pulmonary Fibrosis; Ra | 1986 |
Histopathologic features of phorbol myristate acetate-induced lung injury.
Topics: Acute Disease; Animals; Bronchi; Dose-Response Relationship, Drug; Drug Administration Schedule; Fem | 1985 |