hydroxyproline has been researched along with Choline Deficiency in 14 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study sought to determine whether excess hepatic iron potentiates liver injury in the methionine choline-deficient (MCD) model of non-alcoholic fatty liver disease (NAFLD)." | 3.73 | Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease. ( Hall, Pde L; Kirsch, R; Marais, AD; Sijtsema, HP; Tlali, M, 2006) |
| "Characteristics of nonalcoholic steatohepatitis-related liver fibrosis in KO-MCD/HF group were verified by hepatic histological analyses." | 1.56 | CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease. ( Jiang, Q; Li, G; Liu, B; Xu, K; Zhang, J, 2020) |
| "Early detection and accurate staging of liver fibrosis is critically important for patient management." | 1.51 | Imaging Fibrogenesis in a Diet-Induced Model of Nonalcoholic Steatohepatitis (NASH). ( Boominathan, R; Cheng, P; Chong, YC; Deng, X; Goggi, JL; Han, W; Hartimath, SV; Robins, EG; Soh, V; Tan, PW; Yong, FF, 2019) |
| "Ipragliflozin is a selective sodium glucose cotransporter 2 (SGLT2) inhibitor that increases urinary glucose excretion by inhibiting renal glucose reabsorption and thereby causes a subsequent antihyperglycemic effect." | 1.42 | Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats. ( Hayashizaki-Someya, Y; Koide, K; Kurosaki, E; Mitori, H; Takakura, S; Takasu, T; Yamazaki, S, 2015) |
| "Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis." | 1.34 | Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis. ( Accatino, L; Aguayo, G; Arrese, M; Duarte, I; Ibañez, P; Miquel, JF; Pizarro, M; Solis, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Hartimath, SV | 1 |
| Boominathan, R | 1 |
| Soh, V | 1 |
| Cheng, P | 1 |
| Deng, X | 1 |
| Chong, YC | 1 |
| Yong, FF | 1 |
| Tan, PW | 1 |
| Han, W | 1 |
| Robins, EG | 1 |
| Goggi, JL | 1 |
| Li, G | 1 |
| Zhang, J | 1 |
| Jiang, Q | 1 |
| Liu, B | 1 |
| Xu, K | 1 |
| Hayashizaki-Someya, Y | 1 |
| Kurosaki, E | 1 |
| Takasu, T | 1 |
| Mitori, H | 1 |
| Yamazaki, S | 1 |
| Koide, K | 1 |
| Takakura, S | 1 |
| Jin, H | 1 |
| Sakaida, I | 4 |
| Tsuchiya, M | 1 |
| Okita, K | 4 |
| Kirsch, R | 1 |
| Sijtsema, HP | 1 |
| Tlali, M | 1 |
| Marais, AD | 1 |
| Hall, Pde L | 1 |
| Ibañez, P | 1 |
| Solis, N | 1 |
| Pizarro, M | 1 |
| Aguayo, G | 1 |
| Duarte, I | 1 |
| Miquel, JF | 1 |
| Accatino, L | 1 |
| Arrese, M | 1 |
| Kubota, M | 2 |
| Kayano, K | 2 |
| Takenaka, K | 2 |
| Mori, K | 1 |
| Matsumura, Y | 2 |
| Akiyama, S | 1 |
| Hayashi, K | 1 |
| Ishige, A | 1 |
| Takada, A | 1 |
| Porta, EA | 1 |
| Hartroft, WS | 1 |
| Dodson, VN | 1 |
| Ketchum, DF | 1 |
| Friberg, RD | 1 |
| Iturriaga, H | 2 |
| Peterman, M | 2 |
| Ugarte, G | 2 |
| Iriarte, P | 1 |
| Bengmark, S | 1 |
| Ekdahl, PH | 1 |
| Gottfries, A | 1 |
| Mobacken, H | 1 |
| Olsson, R | 1 |
| Rehnström, B | 1 |
| Scherstén, T | 1 |
14 other studies available for hydroxyproline and Choline Deficiency
| Article | Year |
|---|---|
Imaging Fibrogenesis in a Diet-Induced Model of Nonalcoholic Steatohepatitis (NASH).
Topics: Actins; Animals; Choline Deficiency; Collagen; Diet, High-Fat; Disease Progression; Early Diagnosis; | 2019 |
CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Choline Deficiency; Cyclic AMP Response Element-Binding Protein; Diet | 2020 |
Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats.
Topics: Amino Acids; Animals; Choline Deficiency; Food, Formulated; Glucosides; Hydroxyproline; Hypoglycemic | 2015 |
Herbal medicine Rhei rhizome prevents liver fibrosis in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.
Topics: Actins; Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Choline Deficienc | 2005 |
Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Fatty Liver; | 2006 |
Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty | 2007 |
Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.
Topics: Amino Acids; Animals; Choline Deficiency; Diet; Disease Models, Animal; Glutathione Transferase; Hyd | 1994 |
The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet.
Topics: Amino Acids; Animals; Choline Deficiency; Gene Expression; Hydroxyproline; Liver; Liver Cirrhosis, E | 1996 |
Herbal medicine Sho-saiko-to (TJ-9) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.
Topics: Amino Acids; Animals; Antineoplastic Agents; Biomarkers; Cell Division; Choline Deficiency; Diet; Dr | 1998 |
Correlation of structural and functional recovery from cirrhosis in rats treated with lipotropic diets.
Topics: Animals; Autoradiography; Choline; Choline Deficiency; Dietary Fats; Dietary Proteins; DNA; Histocyt | 1966 |
Chemical, histologic and immunologic responses in rats to CCl4. II. Relative influence of choline deficiency.
Topics: Animals; Antibodies, Anti-Idiotypic; Carbon Tetrachloride Poisoning; Choline Deficiency; Hemagglutin | 1967 |
[Urinary excretion of hydroxyproline in dietetic cirrhosis in rats].
Topics: Age Factors; Animals; Body Weight; Choline Deficiency; Collagen; Hydroxyproline; Liver; Liver Cirrho | 1967 |
[Experimental liver cirrhosis. Transaminase activity, collagen deposit and cell proliferation in the rat with dietetic cirrhosis].
Topics: Animals; Aspartate Aminotransferases; Choline Deficiency; Collagen; Hydroxyproline; Liver Cirrhosis, | 1967 |
Influence of testosterone treatment in experimental nutritional hepatic cirrhosis in the rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biopsy; Body Weight; Choline Deficiency; | 1966 |