hydroxyproline has been researched along with Cholestasis in 20 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The extent of fibrosis was also determined using various assays, such as immunohistochemistry, quantitative real-time PCR (qPCR), and hydroxyproline assays." | 8.12 | Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis. ( Huang, X; Jiang, Z; Miao, Y; Tang, Q; Wang, J; Wu, Q; Xu, Y; Yu, Q; Yuan, Z; Zhang, H; Zhang, L; Zhang, Z, 2022) |
| "Cholestasis is a disorder characterized by impaired bile flow and accumulation of cytotoxic bile acids in the liver." | 5.48 | Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications. ( Ahmadi, A; Azarpira, N; Esfandiari, A; Ghanbarinejad, V; Heidari, R; Mohammadi, H; Niknahad, H, 2018) |
| " The extent of fibrosis was also determined using various assays, such as immunohistochemistry, quantitative real-time PCR (qPCR), and hydroxyproline assays." | 4.12 | Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis. ( Huang, X; Jiang, Z; Miao, Y; Tang, Q; Wang, J; Wu, Q; Xu, Y; Yu, Q; Yuan, Z; Zhang, H; Zhang, L; Zhang, Z, 2022) |
| "The quercetin acts as an enzyme inducer by renewing the glutathione peroxidase activity and inhibiting the oxidation of proteins and hence decreases the oxidative stress." | 1.56 | Extraction and Identification of Two Flavonoids in Phlomoides hyoscyamoides as an Endemic Plant of Iran: The Role of Quercetin in the Activation of the Glutathione Peroxidase, the Improvement of the Hydroxyproline and Protein Oxidation in Bile Duct-Ligate ( Doustimotlagh, AH; Eftekhari, M; Mansourian, M; Taheri, S, 2020) |
| "Cholestasis is a disorder characterized by impaired bile flow and accumulation of cytotoxic bile acids in the liver." | 1.48 | Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications. ( Ahmadi, A; Azarpira, N; Esfandiari, A; Ghanbarinejad, V; Heidari, R; Mohammadi, H; Niknahad, H, 2018) |
| "Quercetin is a flavonoid with antifibrotic, and hepatoprotective properties." | 1.46 | Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats. ( Eskandari-Nasab, E; Ghoreshi, ZA; Kabirifar, R; Karimollah, A; Moradi, A; Safari, F, 2017) |
| "Cholestatic liver fibrosis, characterized by excessive accumulation of extracellular matrix (ECM) proteins, is associated with bile acid-induced oxidative stress and lipid peroxidation." | 1.38 | Aqueous extract of Artemisia iwayomogi Kitamura attenuates cholestatic liver fibrosis in a rat model of bile duct ligation. ( Choi, MK; Han, JM; Hwang, SY; Kim, HG; Lee, JS; Park, HJ; Son, CG; Son, SW; Wang, JH, 2012) |
| "Endotoxemia was prominent in the IA + BDL group from POD 3 (P = 0." | 1.30 | The effect of oral sodium taurocholate on endotoxemia and intestinal anastomotic wound healing in rats with obstructive jaundice. ( Alponat, A; Altinkaya, E; Göksel, S; Sariyar, M; Sayan, M; Yavuz, N, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Yuan, Z | 1 |
| Zhang, H | 1 |
| Wu, Q | 1 |
| Miao, Y | 1 |
| Xu, Y | 1 |
| Yu, Q | 1 |
| Huang, X | 2 |
| Zhang, Z | 1 |
| Tang, Q | 1 |
| Zhang, L | 1 |
| Jiang, Z | 1 |
| Doustimotlagh, AH | 1 |
| Taheri, S | 1 |
| Mansourian, M | 1 |
| Eftekhari, M | 1 |
| Heidari, R | 1 |
| Ghanbarinejad, V | 1 |
| Mohammadi, H | 1 |
| Ahmadi, A | 1 |
| Esfandiari, A | 1 |
| Azarpira, N | 1 |
| Niknahad, H | 1 |
| Mahmoud, MF | 1 |
| Swefy, SE | 1 |
| Hasan, RA | 1 |
| Ibrahim, A | 1 |
| Kabirifar, R | 1 |
| Ghoreshi, ZA | 1 |
| Safari, F | 1 |
| Karimollah, A | 1 |
| Moradi, A | 1 |
| Eskandari-Nasab, E | 1 |
| Tomur, A | 1 |
| Kanter, M | 1 |
| Gurel, A | 1 |
| Erboga, M | 1 |
| Han, JM | 2 |
| Kim, HG | 2 |
| Choi, MK | 2 |
| Lee, JS | 3 |
| Park, HJ | 1 |
| Wang, JH | 2 |
| Son, SW | 2 |
| Hwang, SY | 1 |
| Son, CG | 2 |
| Lee, HW | 1 |
| Lee, DS | 1 |
| Xu, J | 1 |
| Lee, G | 1 |
| Wang, H | 1 |
| Vierling, JM | 1 |
| Maher, JJ | 1 |
| Askew, AR | 1 |
| Bates, GJ | 1 |
| Balderson, G | 1 |
| Gerling, B | 1 |
| Becker, M | 1 |
| Waldschmidt, J | 1 |
| Rehmann, M | 1 |
| Schuppan, D | 3 |
| Park, EJ | 1 |
| Ko, G | 1 |
| Kim, J | 1 |
| Sohn, DH | 1 |
| Cho, JJ | 1 |
| Hocher, B | 1 |
| Herbst, H | 1 |
| Jia, JD | 2 |
| Ruehl, M | 1 |
| Hahn, EG | 2 |
| Riecken, EO | 2 |
| Sayan, M | 1 |
| Alponat, A | 1 |
| Yavuz, N | 1 |
| Altinkaya, E | 1 |
| Göksel, S | 1 |
| Sariyar, M | 1 |
| Raetsch, C | 1 |
| Boigk, G | 1 |
| Bauer, M | 1 |
| Koyama, K | 1 |
| Muto, I | 1 |
| Yamauchi, H | 1 |
| Takagi, Y | 1 |
| Anezaki, T | 1 |
| Casini, A | 1 |
| Lippe, IT | 1 |
| Evangelista, S | 1 |
| Geppetti, P | 1 |
| Santicioli, P | 1 |
| Urso, C | 1 |
| Maggi, CA | 1 |
| Surrenti, C | 1 |
| Beseda, IN | 1 |
| Bychkova, VI | 1 |
| James, J | 1 |
| Bosch, KS | 1 |
| Aronson, DC | 1 |
| Houtkooper, JM | 1 |
| Cerda, JJ | 1 |
| Toskes, PP | 1 |
| Shopa, NA | 1 |
| Wilkinson, JH | 1 |
20 other studies available for hydroxyproline and Cholestasis
| Article | Year |
|---|---|
Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis.
Topics: Alkaline Phosphatase; Animals; Chenodeoxycholic Acid; Cholestasis; Fibrosis; Hydroxyproline; Liver; | 2022 |
Extraction and Identification of Two Flavonoids in Phlomoides hyoscyamoides as an Endemic Plant of Iran: The Role of Quercetin in the Activation of the Glutathione Peroxidase, the Improvement of the Hydroxyproline and Protein Oxidation in Bile Duct-Ligate
Topics: Animals; Bile Ducts; Chemical and Drug Induced Liver Injury; Cholestasis; Flavonoids; Glutathione Pe | 2020 |
Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications.
Topics: Animals; Bile Ducts; Biomarkers; Cholestasis; Dietary Supplements; Dithiothreitol; Hydroxyproline; K | 2018 |
Role of cannabinoid receptors in hepatic fibrosis and apoptosis associated with bile duct ligation in rats.
Topics: Animals; Apoptosis; Bile Ducts; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cho | 2014 |
Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats.
Topics: Actins; Animals; Antioxidants; Catalase; Cholestasis; Collagen Type I; Cytoprotection; Down-Regulati | 2017 |
The efficiency of CAPE on retardation of hepatic fibrosis in biliary obstructed rats.
Topics: Animals; Caffeic Acids; Cell Proliferation; Cholestasis; Glutathione Peroxidase; Hydroxyproline; Imm | 2011 |
Aqueous extract of Artemisia iwayomogi Kitamura attenuates cholestatic liver fibrosis in a rat model of bile duct ligation.
Topics: Actins; Animals; Antioxidants; Artemisia; Bile Ducts; Cholestasis; Collagen Type I; Collagen Type I, | 2012 |
CGX, a multiple herbal drug, improves cholestatic liver fibrosis in a bile duct ligation-induced rat model.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Catala | 2013 |
Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Biomarkers; Chemical and Drug Induced Liver Injury; Chemoki | 2004 |
Jaundice and the effect of sodium taurocholate taken orally upon abdominal wound healing.
Topics: Administration, Oral; Animals; Bile Ducts; Cholestasis; Female; Hydroxyproline; Ligation; Premedicat | 1984 |
Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis.
Topics: Animals; Cholestasis; Disease Models, Animal; Female; Humans; Hydroxyproline; Liver Cirrhosis, Exper | 1996 |
Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction.
Topics: Animals; Basidiomycota; Body Weight; Cholestasis; Common Bile Duct Diseases; Female; Glycyrrhetinic | 1997 |
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Ascites; Aspartate Aminot | 2000 |
The effect of oral sodium taurocholate on endotoxemia and intestinal anastomotic wound healing in rats with obstructive jaundice.
Topics: Anastomosis, Surgical; Animals; Cholestasis; Endotoxemia; Female; Hydroxyproline; Ileum; Intestines; | 1997 |
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
Topics: Administration, Oral; Animals; Cholestasis; Chronic Disease; Collagen; Cytokines; DNA Probes; DNA, C | 2002 |
Biochemical study of fibrosis in the rat liver in biliary obstruction.
Topics: Animals; Carbon Radioisotopes; Cholestasis; Collagen; Common Bile Duct; Hexosamines; Hydroxyproline; | 1975 |
Sensory denervation with capsaicin reduces the liver collagen deposition induced by common bile duct obstruction in rats.
Topics: Animals; Biliary Tract; Body Weight; Capsaicin; Cholestasis; Collagen; Common Bile Duct Diseases; Ea | 1991 |
[Diagnosis of cholestatic forms of viral hepatitis, its complications and outcomes].
Topics: Cholestasis; Cholesterol; Diagnosis, Differential; Hepatitis, Viral, Human; Humans; Hydroxyproline; | 1990 |
Sirius red histophotometry and spectrophotometry of sections in the assessment of the collagen content of liver tissue and its application in growing rat liver.
Topics: Animals; Azo Compounds; Cholestasis; Collagen; Coloring Agents; Histocytochemistry; Hydroxyproline; | 1990 |
The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Bone Diseases; Cholest | 1970 |