Page last updated: 2024-11-06

hydroxyproline and Cardiovascular Stroke

hydroxyproline has been researched along with Cardiovascular Stroke in 95 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Empagliflozin administered early after myocardial infarction reduce myocardial fibrosis and inhibit the TGF-β1/Smad3 fibrotic pathway, probably prior to exerting any hemodynamic or physiological effect."8.02The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats. ( Atar, S; Bandel, N; Daud, E; Ertracht, O; Moady, G; Reuveni, T; Shehadeh, M, 2021)
"Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1) concentration, myocyte hypertrophy, left ventricular architecture, and in vitro and in vivo cardiac function."7.79Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction. ( Azevedo, PS; Chiuso-Minicucci, F; dos Santos, PP; Gonçalves, AF; Minicucci, MF; Okoshi, K; Paiva, SA; Pereira, EJ; Polegato, BF; Rafacho, BP; Silva, RA; Zornoff, LA, 2013)
" Thus, we evaluated the effects of atorvastatin on cardiac function, remodeling, fibrosis, and apoptosis after myocardial infarction (MI)."7.77Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. ( Bi, Q; Bolli, R; Dawn, B; Hunt, G; Peng, Y; Sanganalmath, SK; Sato, H; Shirk, G; Tang, XL; Vincent, RJ, 2011)
"To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)."7.74[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008)
"Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis."7.73Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006)
"Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure."7.71Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002)
"We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)."7.71Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002)
"We investigated the effect of indomethacin, a widely used nonsteroidal antiinflammatory drug, on the healing of myocardial infarction (MI)."7.66Indomethacin-induced scar thinning after experimental myocardial infarction. ( Braunwald, E; Brown, EJ; Hale, S; Hammerman, H; Kloner, RA; Schoen, FJ, 1983)
"Empagliflozin administered early after myocardial infarction reduce myocardial fibrosis and inhibit the TGF-β1/Smad3 fibrotic pathway, probably prior to exerting any hemodynamic or physiological effect."4.02The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats. ( Atar, S; Bandel, N; Daud, E; Ertracht, O; Moady, G; Reuveni, T; Shehadeh, M, 2021)
" Isoproterenol (ISO)-induced cardiotoxicity challenged mice were treated with NY for 28 days at two doses (0."3.88Nanoyttria attenuates isoproterenol-induced cardiac injury. ( Godugu, C; Khurana, A; Kumari, P, 2018)
"Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1) concentration, myocyte hypertrophy, left ventricular architecture, and in vitro and in vivo cardiac function."3.79Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction. ( Azevedo, PS; Chiuso-Minicucci, F; dos Santos, PP; Gonçalves, AF; Minicucci, MF; Okoshi, K; Paiva, SA; Pereira, EJ; Polegato, BF; Rafacho, BP; Silva, RA; Zornoff, LA, 2013)
" Thus, we evaluated the effects of atorvastatin on cardiac function, remodeling, fibrosis, and apoptosis after myocardial infarction (MI)."3.77Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. ( Bi, Q; Bolli, R; Dawn, B; Hunt, G; Peng, Y; Sanganalmath, SK; Sato, H; Shirk, G; Tang, XL; Vincent, RJ, 2011)
"To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)."3.74[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008)
"To determine whether therapy with the angiotensin II type 1 receptor blocker (ARB) candesartan and the comparator angiotensin-converting-enzyme inhibitor (ACEI) enalapril during healing after reperfused ST-elevation myocardial infarction (RSTEMI) limit adverse remodeling of infarct zone (IZ) collagens and left ventricular (LV) diastolic dysfunction, we randomized 24 dogs surviving anterior RSTEMI (90-min coronary occlusion) to placebo, candesartan, and enalapril therapy between day 2 and 42."3.74Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction. ( Idikio, H; Jugdutt, BI; Uwiera, RR, 2007)
"Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis."3.73Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006)
"Canrenone attenuates LV interstitial remodeling and reduces filling pressures in rats with postinfarction heart failure."3.71Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. ( Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M, 2002)
"We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)."3.71Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002)
"We sought to compare the effects of two different beta-blockers, carvedilol and metoprolol, to an angiotensin-converting enzyme (ACE) inhibitor (captopril) on myocardial collagen deposition during healing and ventricular remodeling after myocardial infarction (MI)."3.70Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. ( Chow, LT; Sanderson, JE; Wei, S, 2000)
" This study aimed to analyze the effects of lisinopril on mortality rate, cardiac function, degree of cardiac hypertrophy and fibrosis in rats with different infarct sizes."3.70Effects of lisinopril on experimental ischemia in rats. Influence of infarct size. ( Matsubara, BB; Matsubara, LS; Paiva, SA; Spadaro, J; Tornero, MT; Zornoff, LA, 1999)
"To evaluate the effects of losartan on ventricular remodeling and on survival after myocardial infarction in rats."3.70Effects of losartan on ventricular remodeling in experimental infarction in rats. ( Matsubara, BB; Matsubara, LS; Paiva, SA; Spadaro, J; Zornoff, LA, 2000)
"Myocyte morphometrics (isolated cell technique) and collagen content (hydroxyproline analysis) were assessed 28 days following experimental myocardial infarction from rats with permanently ligated left coronary vessels (NRP; n = 10) compared with rats who underwent reperfusion 150 minutes after ligation (RP; n = 11) and a sham-operated group (n = 10)."3.69The effect of delayed reperfusion following infarction in the rat on structural changes in viable myocardium. ( Carlyle, W; Chu, C; Francis, G; Hartman, M; Hauer, K; Judd, D; McDonald, K; Toher, C, 1997)
"To assess whether the reduction in ischaemic injury during acute myocardial infarction induced by nitroglycerin (NTG) results in a decrease in tissue necrosis, 96 rats were assigned to two groups."3.67Long-term protection of ischaemic myocardium by nitroglycerin ointment. ( Ambrosio, G; Brevetti, G; Cataffo, A; Chiariello, M; Condorelli, M; Pollice, U, 1984)
"A total of 136 patients with trans- and 200 with non-transmural myocardial infarction (MI) were examined over time for chlorine-soluble mucoprotein (MP), serum hexoses (SH), their fraction-hexoses of glycosaminoglycans (H-GAG), and hexoses of glycoproteins (H-GP), serum, plasma and urine hydroxyproline (SHP, PHP, UHP)."3.67[Clinical regularities of myocardial infarction repair]. ( Kaliabin, GA; Movshovich, BL, 1989)
"The healing process of myocardial infarction was studied with special reference to the production of collagen by the determinations of prolylhydroxylase (PHase) activity and contents of hydroxyproline (Hyp) of the collagen subfractions, i."3.67Studies on collagen in the experimental myocardial infarction. ( Katagiri, T; Sasai, Y; Sekita, S; Takeda, K, 1985)
"We investigated the effect of indomethacin, a widely used nonsteroidal antiinflammatory drug, on the healing of myocardial infarction (MI)."3.66Indomethacin-induced scar thinning after experimental myocardial infarction. ( Braunwald, E; Brown, EJ; Hale, S; Hammerman, H; Kloner, RA; Schoen, FJ, 1983)
"Mature male Sprague-Dawley rats were subjected to an isoproterenol-induced myocardial infarction."3.65Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction. ( Judd, JT; Wexler, BC, 1975)
"A rat model of ventricular remodeling after myocardial infarction was established by left coronary artery ligation."1.42Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats. ( Chen, C; Gao, J; Gao, Y; Guo, J; Wang, H; Wu, R, 2015)
"Endothelial dysfunction can lead to congestive heart failure and the activation of endothelial ATP-sensitive potassium (K(ATP)) channels may contribute to endothelial protection."1.40Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy. ( Cui, WY; Long, CL; Wang, H; Zhang, YF; Zhong, ML; Zhou, HM, 2014)
"EERS attenuates ventricular remodeling."1.38Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats. ( Chen, CX; Huang, XY; Li, YM; Liu, Y; Wu, XM; Zhang, XM, 2012)
"The experimental ventricular remodeling was induced with ligating the left anterior descending branch of the coronary artery of the rats."1.36Effects of Chinese herb medicine Radix Scrophulariae on ventricular remodeling. ( Chen, CX; Gu, WL; Liu, Y; Lü, J; Wu, Q; Zhang, SJ, 2010)
"Ramipril treatment caused an increase in catalase, glutathione peroxidase, and SOD activity in the LV tissue."1.35A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. ( Chao, CL; Chen, CY; Chen, MF; Ho, YL; Hsu, HC; Lee, BC; Lin, HJ; Lin, YH, 2008)
"Cells isolated from the heart scar were identified as myofibroblasts."1.35Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar. ( Dabrowski, R; Drobnik, J; Jakubowski, L; Karbownik-Lewińska, M; Olczak, S; Szczepanowska, A; Słotwińska, D, 2008)
"Left ventricular remodeling and function were followed for 12 weeks post-MI."1.32Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice. ( Cavasin, MA; Menon, S; Tao, Z; Yang, XP, 2004)
"Scarring is markedly reduced in MRL mice compared with C57BL/6 mice, consistent with both the reduced hydroxyproline levels seen after injury and an elevated cardiomyocyte mitotic index of 10-20% for the MRL compared with 1-3% for the C57BL/6."1.31Heart regeneration in adult MRL mice. ( Bedelbaeva, K; Heber-Katz, E; Lankford, EB; Leferovich, JM; Samulewicz, S; Zhang, XM; Zwas, D, 2001)
"The hydroxyproline/proline ratio was increased by 64% in MI-control and reduced to the sham value in MI-FG041 rats."1.31Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction. ( Bean, M; Brenner, MC; Buttrick, PM; Geenen, D; Huang, X; Nwogu, JI, 2001)
"Captopril and losartan treatments were equally efficient to attenuate these parameters in both ventricles."1.30[Activation of the cardiac angiotensin-converting enzyme after myocardial infarction and its role in ventricular remodeling]. ( Busatto, VC; de Moraes, AC; Gomes, Mda G; Milanez, Mda C; Mill, JG, 1997)
"Ischemic mitral regurgitation or ventricular wall motion abnormalities will alter the stress distribution in the mitral valve."1.30Altered collagen concentration in mitral valve leaflets: biochemical and finite element analysis. ( Cochran, RP; Kunzelman, KS; Quick, DW, 1998)
"Hydroxyproline levels were determined."1.30Reduced injury and scar in acute myocardial infarctions treated with human growth hormone. ( Castagnino, HE; Hamamura, S; Jörg, ME; Laguens, RP, 1998)
"Hydroxyproline contents were significantly increased in the noninfarcted septum."1.29Collagen remodeling after myocardial infarction in the rat heart. ( Cleutjens, JP; Daemen, MJ; Smiths, JF; Verluyten, MJ, 1995)
"The hydroxyproline assay was used to determine collagen and elastin content biochemically."1.29Peripheral vascular alterations during experimental heart failure in the rat. Do they exist? ( Aarts, PJ; Arends, JW; Daemen, MJ; Heeneman, S; Leenders, PJ; Smits, JF, 1995)
"The ratios of the scar thickness to normal wall thickness were superoxide dismutase 0."1.27Superoxide dismutase does not cause scar thinning after myocardial infarction. ( Abrams, GD; Buda, AJ; Lucchesi, BR; Phan, S; Pitt, B; Shea, MJ; Vaporciyan, A; Werns, SW, 1987)
"The nonreperfused scars had a higher proportion of fibrous tissue (73 +/- 3%) by histological evaluation and a 35% higher hydroxyproline content (31 +/- 2 mg/g dry weight, P less than 0."1.27Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue. ( Apstein, CS; Bing, OH; Connelly, CM; Dunn-Lanchantin, DM; Franzblau, C; Kloner, RA; Osmers, EL; Vogel, WM; Wiegner, AW, 1985)
"The healing of myocardial infarction is accompanied by an increased accumulation of collagen in the heart muscle."1.26Collagen metabolism in patients with myocardial infarction. ( Cerazy, B; Drózdz, M; Jendryczko, A; Kucharz, E, 1982)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199042 (44.21)18.7374
1990's18 (18.95)18.2507
2000's20 (21.05)29.6817
2010's14 (14.74)24.3611
2020's1 (1.05)2.80

Authors

AuthorsStudies
Daud, E1
Ertracht, O1
Bandel, N1
Moady, G1
Shehadeh, M1
Reuveni, T1
Atar, S1
Zhang, S1
Cui, R1
Godugu, C1
Kumari, P1
Khurana, A1
Minicucci, MF2
dos Santos, PP1
Rafacho, BP2
Gonçalves, AF2
Silva, RA1
Chiuso-Minicucci, F1
Azevedo, PS2
Polegato, BF2
Okoshi, K2
Pereira, EJ2
Paiva, SA4
Zornoff, LA4
Santos, PP1
Ardisson, LP1
Batista, DF1
Lu, Y1
Liu, JJ1
Bi, XY1
Yu, XJ1
Kong, SS1
Qin, FF1
Zhou, J1
Zang, WJ1
Zhou, HM1
Zhong, ML1
Zhang, YF1
Cui, WY1
Long, CL1
Wang, H2
Gao, Y2
Gao, J1
Chen, C1
Guo, J1
Wu, R1
Li, C1
Han, R1
Kang, L1
Wang, J1
Li, Y1
He, J1
Tian, J1
Chen, CY1
Lee, BC1
Hsu, HC1
Lin, HJ1
Chao, CL1
Lin, YH1
Ho, YL1
Chen, MF1
Sun, T1
Shen, LH1
Chen, H1
Li, HW1
Guo, CY1
Li, ZZ1
Tang, CS1
French, CJ1
Zaman, AK1
Sobel, BE2
Gu, WL1
Chen, CX2
Wu, Q1
Lü, J1
Liu, Y2
Zhang, SJ1
Kim, LB1
Putiatina, AN1
Tang, XL1
Sanganalmath, SK1
Sato, H1
Bi, Q1
Hunt, G1
Vincent, RJ1
Peng, Y1
Shirk, G1
Dawn, B1
Bolli, R2
Huang, XY1
Zhang, XM2
Wu, XM1
Li, YM1
Yengo, CM1
Zimmerman, SD1
McCormick, RJ1
Thomas, DP1
Yuan, QY1
Huang, J1
Chu, BC1
Li, XJ1
Li, XS1
Si, LY1
Cittadini, A1
Casaburi, C1
Monti, MG1
Di Gianni, A1
Serpico, R1
Scherillo, G1
Saldamarco, L1
Vanasia, M1
Saccà, L1
Itter, G1
Jung, W1
Juretschke, P1
Schoelkens, BA1
Linz, W1
Cavasin, MA1
Tao, Z1
Menon, S1
Yang, XP1
Jayasankar, V1
Woo, YJ1
Bish, LT1
Pirolli, TJ1
Berry, MF1
Burdick, J1
Bhalla, RC1
Sharma, RV1
Gardner, TJ1
Sweeney, HL1
Camp, TM1
Tyagi, SC2
Aru, GM1
Hayden, MR1
Mehta, JL1
Yndestad, A1
Vinge, LE1
Bjørnerheim, R1
Ueland, T1
Wang, JE1
Frøland, SS1
Attramadal, H1
Aukrust, P1
Oie, E1
Du, XJ1
Gao, XM1
Kiriazis, H1
Moore, XL1
Ming, Z1
Su, Y1
Finch, AM1
Hannan, RA1
Dart, AM1
Graham, RM1
Agnoletti, G1
Cargnoni, A1
Agnoletti, L1
Di Marcello, M1
Balzarini, P1
Pasini, E1
Gitti, G1
Martina, P1
Ardesi, R1
Ferrari, R1
Jugdutt, BI9
Idikio, H3
Uwiera, RR2
Drobnik, J1
Karbownik-Lewińska, M1
Szczepanowska, A1
Słotwińska, D1
Olczak, S1
Jakubowski, L1
Dabrowski, R1
Lerman, RH1
Apstein, CS3
Kagan, HM1
Osmers, EL2
Chichester, CO1
Vogel, WM2
Connelly, CM2
Steffee, WP1
Movshovich, BL8
Mimbs, JW2
O'Donnell, M2
Bauwens, D1
Miller, JW1
Chiariello, M2
Brevetti, G1
Ambrosio, G2
Cataffo, A1
Pollice, U1
Condorelli, M1
Roberts, CS1
Schoen, FJ6
Kloner, RA7
Nikitin, JP1
Korobkowa, HN1
Hammerman, H5
Braunwald, E5
Brown, EJ2
Hale, S3
Kucharz, E1
Drózdz, M1
Cerazy, B1
Jendryczko, A1
Miller, JG1
Cleutjens, JP1
Verluyten, MJ1
Smiths, JF1
Daemen, MJ2
Heeneman, S1
Leenders, PJ1
Aarts, PJ1
Smits, JF1
Arends, JW1
Gupta, KB1
Ratcliffe, MB1
Fallert, MA1
Edmunds, LH1
Bogen, DK1
Sanbe, A1
Tanonaka, K1
Hanaoka, Y1
Katoh, T1
Takeo, S1
Wiggers, H1
Klebe, T1
Heickendorff, L1
Høst, NB1
Danielsen, CC1
Baandrup, U1
Andersen, HR1
Jonderko, G1
Kucharz, EJ1
Fink, M1
Filipek, B1
Kotrys-Puchalska, E1
Wedrychowska, A1
Lucas, A1
Khan, MI2
Ju, H1
Zhao, S1
Jassal, DS1
Dixon, IM1
McDonald, K1
Chu, C1
Francis, G1
Judd, D1
Carlyle, W1
Toher, C1
Hauer, K1
Hartman, M1
Mill, JG1
Milanez, Mda C1
Busatto, VC1
de Moraes, AC1
Gomes, Mda G1
Kunzelman, KS1
Quick, DW1
Cochran, RP1
Laguens, RP1
Castagnino, HE1
Jörg, ME1
Hamamura, S1
Matsubara, BB2
Matsubara, LS2
Tornero, MT1
Spadaro, J2
Wei, S1
Chow, LT1
Sanderson, JE1
Podesser, BK1
Siwik, DA1
Eberli, FR1
Sam, F1
Ngoy, S1
Lambert, J1
Ngo, K1
Colucci, WS1
Leferovich, JM1
Bedelbaeva, K1
Samulewicz, S1
Zwas, D1
Lankford, EB1
Heber-Katz, E1
Nwogu, JI1
Geenen, D1
Bean, M1
Brenner, MC1
Huang, X1
Buttrick, PM1
Menon, V1
Kumar, D1
Naddachina, TA1
Vinogradov, AV1
Panormov, VV1
Takahashi, S1
Judd, JT2
Wexler, BC2
Litwin, SE1
Raya, TE1
Warner, A1
Litwin, CM1
Goldman, S1
Ravichandran, LV1
Puvanakrishnan, R1
Scholz, TD1
Vandenberg, BF1
Fleagle, SR1
Collins, SM2
Kerber, RE1
Skorton, DJ2
Virmani, R1
Osmialowski, AF1
Kolodgie, FD1
Forman, MB1
Barmotin, GV2
Kinoshenko, EI1
Aliavi, AL1
Vlasenko, MA1
Kaliabin, GA1
Greĭskop, IA1
Sekita, S1
Katagiri, T1
Sasai, Y1
Takeda, K1
Cappelli-Bigazzi, M1
Perrone-Filardi, P1
Brigante, F1
Sifola, C1
Shimazu, T1
Nishioka, H1
Fujiwara, M1
Matsuyama, T1
Ozaki, H1
Hamanaka, Y1
Kitabatake, A1
Inoue, M1
Kamada, T1
Matsumoto, M1
Werns, SW1
Shea, MJ1
Vaporciyan, A1
Phan, S1
Abrams, GD1
Buda, AJ1
Pitt, B1
Lucchesi, BR1
Leshchinskii, LA1
Vtorov, AE1
Hoyt, RH1
Ericksen, EE1
Conyers, D1
Amy, RW1
Alker, KJ1
Cannon, RO1
Rodríguez, ER1
Speir, E1
Yamaguchi, M1
Butany, J1
McManus, BM1
Ferrans, VJ1
Wiegner, AW1
Bing, OH1
Dunn-Lanchantin, DM1
Franzblau, C1
Rupniewska, ZM4
Widomska-Czekajska, T4
Miturzyńska-Stryjecka, H4
Bielak, Z4
Mishurova, VP1
Gudbjarnason, S1
Puri, PS1
Mathes, P1
Ino, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Study of Pirfenidone in the Treatment of Myocardial Fibrosis After Acute Myocardial Infarction: a Phase II Prospective, Randomized, Double-blind,Placebo Controlled Clinical Trial[NCT05531955]Phase 2100 participants (Anticipated)Interventional2022-08-05Active, not recruiting
Efficacy and Safety of an Early Phase Single Bolus r-SAK for Acute Myocardial Infarction: a Multi-center Randomized Clinical Trial (OPTIMA-5)[NCT05023681]Phase 4200 participants (Actual)Interventional2021-10-29Completed
A Single Bolus r-SAK Prior to Primary PCI for ST-elevation Myocardial Infarction (OPTIMA-5): 1-Year Follow-up[NCT05649696]Phase 4210 participants (Actual)Interventional2021-10-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for hydroxyproline and Cardiovascular Stroke

ArticleYear
[Effect of heart infarction on levels of type I procollagen carboxyterminal peptide in blood serum].
    Polskie Archiwum Medycyny Wewnetrznej, 1996, Volume: 96, Issue:6

    Topics: Adult; Aged; Aspartate Aminotransferases; Creatine Kinase; Electrocardiography; Female; Humans; Hydr

1996

Other Studies

94 other studies available for hydroxyproline and Cardiovascular Stroke

ArticleYear
The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats.
    Cardiovascular diabetology, 2021, 07-02, Volume: 20, Issue:1

    Topics: Animals; Benzhydryl Compounds; Collagen; Disease Models, Animal; Fibrosis; Glucosides; Hydroxyprolin

2021
The targeted regulation of miR-26a on PTEN-PI3K/AKT signaling pathway in myocardial fibrosis after myocardial infarction.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:2

    Topics: Animals; Antagomirs; Cell Differentiation; Disease Models, Animal; Fibroblasts; Hydroxyproline; Male

2018
Nanoyttria attenuates isoproterenol-induced cardiac injury.
    Nanomedicine (London, England), 2018, Volume: 13, Issue:23

    Topics: Animals; Cardiotoxicity; Cytokines; Gene Expression Regulation; Heart; Heart Injuries; Hydroxyprolin

2018
Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analysis of Variance; Animals; Blotting, Western; Body Weights and Measures; Collagen; Echocardiogra

2013
Periostin as a modulator of chronic cardiac remodeling after myocardial infarction.
    Clinics (Sao Paulo, Brazil), 2013, Volume: 68, Issue:10

    Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Collagen Type I; Collagen Type III; Diastole; D

2013
Pyridostigmine ameliorates cardiac remodeling induced by myocardial infarction via inhibition of the transforming growth factor-β1/TGF-β1-activated kinase pathway.
    Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:5

    Topics: Animals; Cholinesterase Inhibitors; Fibrosis; Hemodynamics; Hydroxyproline; Male; MAP Kinase Kinase

2014
Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy.
    International journal of molecular medicine, 2014, Volume: 34, Issue:5

    Topics: Administration, Oral; Allyl Compounds; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relation

2014
Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats.
    Planta medica, 2015, Volume: 81, Issue:7

    Topics: Aldosterone; Animals; Antioxidants; Captopril; Collagen; Coronary Occlusion; Coronary Vessels; Endot

2015
Pirfenidone controls the feedback loop of the AT1R/p38 MAPK/renin-angiotensin system axis by regulating liver X receptor-α in myocardial infarction-induced cardiac fibrosis.
    Scientific reports, 2017, 01-16, Volume: 7

    Topics: Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Collagen Type III; Feedback, Physiological;

2017
A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit.
    European journal of heart failure, 2008, Volume: 10, Issue:8

    Topics: Animals; Blotting, Western; Catalase; Cyclophilin A; Down-Regulation; Echocardiography; Electrophore

2008
[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction].
    Zhonghua xin xue guan bing za zhi, 2008, Volume: 36, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibr

2008
Cardiac fibrosis and diastolic dysfunction after myocardial infarction in apolipoprotein E knockout mice.
    Coronary artery disease, 2009, Volume: 20, Issue:7

    Topics: Animals; Apolipoproteins E; Body Weight; Diastole; Disease Models, Animal; Echocardiography, Doppler

2009
Effects of Chinese herb medicine Radix Scrophulariae on ventricular remodeling.
    Die Pharmazie, 2010, Volume: 65, Issue:10

    Topics: Angiotensin II; Animals; Collagen; Coronary Vessels; Hydroxyproline; Ligation; Male; Myocardial Infa

2010
[Dynamics of biochemical markers of reparative fibrosis in uncomplicated course of myocardial infarction].
    Kardiologiia, 2010, Volume: 50, Issue:12

    Topics: Adult; Aged; Biomarkers; Disease Progression; Echocardiography; Electrocardiography; Female; Fibrone

2010
Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Apoptosis; Atorvastatin; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhib

2011
Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Feb-15, Volume: 19, Issue:3-4

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Chemical Analysis; Captopril; Cardiomegaly

2012
Exercise training post-MI favorably modifies heart extracellular matrix in the rat.
    Medicine and science in sports and exercise, 2012, Volume: 44, Issue:6

    Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Collagen; Disease Models, Anima

2012
A targeted high-efficiency angiogenesis strategy as therapy for myocardial infarction.
    Life sciences, 2012, May-15, Volume: 90, Issue:17-18

    Topics: Animals; Coronary Vessels; Dogs; Genetic Therapy; Human Growth Hormone; Humans; Hydroxyproline; Male

2012
Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3

    Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Collagen; Cyclodextrins; Disease Models, Anim

2002
A model of chronic heart failure in spontaneous hypertensive rats (SHR).
    Laboratory animals, 2004, Volume: 38, Issue:2

    Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Hydroxyproline; H

2004
Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice.
    Life sciences, 2004, Sep-17, Volume: 75, Issue:18

    Topics: Acute Disease; Animals; Blood Pressure; Body Weight; Chronic Disease; Collagen; Female; Heart; Heart

2004
Inhibition of matrix metalloproteinase activity by TIMP-1 gene transfer effectively treats ischemic cardiomyopathy.
    Circulation, 2004, Sep-14, Volume: 110, Issue:11 Suppl 1

    Topics: Adenoviridae; Animals; Defective Viruses; Drug Evaluation, Preclinical; Fibrosis; Genes, Synthetic;

2004
Doxycycline ameliorates ischemic and border-zone remodeling and endothelial dysfunction after myocardial infarction in rats.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:6

    Topics: Animals; Cardiotonic Agents; Doxycycline; Endocardium; Hydroxyproline; Matrix Metalloproteinase 2; M

2004
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats.
    European journal of heart failure, 2006, Volume: 8, Issue:8

    Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hydroxyprolin

2006
Transgenic alpha1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival.
    Cardiovascular research, 2006, Sep-01, Volume: 71, Issue:4

    Topics: Actins; Aging; Animals; Atrial Natriuretic Factor; Collagen; Echocardiography; Female; Fibronectins;

2006
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
    Annals of clinical and laboratory science, 2006,Summer, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R

2006
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
    Annals of clinical and laboratory science, 2006,Summer, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R

2006
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
    Annals of clinical and laboratory science, 2006,Summer, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R

2006
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
    Annals of clinical and laboratory science, 2006,Summer, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R

2006
Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction.
    Molecular and cellular biochemistry, 2007, Volume: 303, Issue:1-2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting En

2007
Therapeutic drugs during healing after myocardial infarction modify infarct collagens and ventricular distensibility at elevated pressures.
    Molecular and cellular biochemistry, 2007, Volume: 304, Issue:1-2

    Topics: Animals; Blood Pressure; Collagen; Dogs; Drug-Related Side Effects and Adverse Reactions; Hydroxypro

2007
Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: Animals; Cells, Cultured; Cicatrix; Collagen; Fibroblasts; Gene Expression Regulation; Hydroxyprolin

2008
Myocardial healing and repair after experimental infarction in the rabbit.
    Circulation research, 1983, Volume: 53, Issue:3

    Topics: Animals; Collagen; Coronary Vessels; Hydroxyproline; Ligation; Male; Myocardial Infarction; Procolla

1983
[Myocardial repair in infarction: parallels of clinico-laboratory indices, morphology and biochemistry of infarcted myocardium].
    Kardiologiia, 1982, Volume: 22, Issue:9

    Topics: Adult; Aged; Blood Sedimentation; Female; Fibrinogen; Glycosaminoglycans; Humans; Hydroxyproline; Le

1982
The dependence of ultrasonic attenuation and backscatter on collagen content in dog and rabbit hearts.
    Circulation research, 1980, Volume: 47, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Buffers; Collagen; Coronary Vessels; Dogs; Hydroxyproline; Mic

1980
Long-term protection of ischaemic myocardium by nitroglycerin ointment.
    Cardiovascular research, 1984, Volume: 18, Issue:5

    Topics: Animals; Collagen; Creatine Kinase; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Necrosi

1984
Effect of coronary reperfusion on myocardial hemorrhage and infarct healing.
    The American journal of cardiology, 1983, Sep-01, Volume: 52, Issue:5

    Topics: Animals; Coronary Circulation; Coronary Vessels; Creatine Kinase; Dogs; Female; Hemoglobins; Hydroxy

1983
[Hydroxyproline in blood and urine in myocardial infarct].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1983, Jul-15, Volume: 38, Issue:14

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Humans; Hydroxyproline; Male; Middle Aged;

1983
Drug-induced expansion of infarct: morphologic and functional correlations.
    Circulation, 1984, Volume: 69, Issue:3

    Topics: Animals; Dogs; Echocardiography; Female; Heart Ventricles; Hydroxyproline; Indomethacin; Male; Myoca

1984
Scar thinning due to ibuprofen administration after experimental myocardial infarction.
    The American journal of cardiology, 1983, Mar-01, Volume: 51, Issue:5

    Topics: Animals; Aspirin; Dogs; Female; Hydroxyproline; Ibuprofen; Male; Myocardial Infarction; Myocardium

1983
Indomethacin-induced scar thinning after experimental myocardial infarction.
    Circulation, 1983, Volume: 67, Issue:6

    Topics: Animals; Dogs; Female; Hydroxyproline; Indomethacin; Male; Myocardial Infarction; Myocardium

1983
Dose-dependent effects of short-term methylprednisolone on myocardial infarct extent, scar formation, and ventricular function.
    Circulation, 1983, Volume: 68, Issue:2

    Topics: Animals; Cicatrix; Dogs; Dose-Response Relationship, Drug; Echocardiography; Female; Heart Ventricle

1983
Collagen metabolism in patients with myocardial infarction.
    Cor et vasa, 1982, Volume: 24, Issue:5

    Topics: Adult; Aged; Blood Proteins; Carrier Proteins; Collagen; Humans; Hydroxylysine; Hydroxyproline; Midd

1982
Relationship between collagen and ultrasonic backscatter in myocardial tissue.
    The Journal of the Acoustical Society of America, 1981, Volume: 69, Issue:2

    Topics: Animals; Collagen; Dogs; Hydroxyproline; Myocardial Infarction; Myocardium; Ultrasonics

1981
Collagen remodeling after myocardial infarction in the rat heart.
    The American journal of pathology, 1995, Volume: 147, Issue:2

    Topics: Animals; Blotting, Northern; Collagen; Heart; Hydroxyproline; Immunohistochemistry; In Situ Hybridiz

1995
Peripheral vascular alterations during experimental heart failure in the rat. Do they exist?
    Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:9

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Flow Velocity; Blood Vessels; Cardiac Output, Low;

1995
Changes in passive mechanical stiffness of myocardial tissue with aneurysm formation.
    Circulation, 1994, Volume: 89, Issue:5

    Topics: Animals; Elasticity; Heart; Heart Aneurysm; Hydroxyproline; Myocardial Contraction; Myocardial Infar

1994
Regional energy metabolism of failing hearts following myocardial infarction.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:9

    Topics: Acute Disease; Animals; Energy Metabolism; Heart; Hemodynamics; Hydroxyproline; Myocardial Infarctio

1993
Ischemia and reperfusion of the porcine myocardium: effect on collagen.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:1

    Topics: Analysis of Variance; Animals; Biomarkers; Collagen; Collagen Type I; Creatine Kinase; Disease Model

1997
Effect of angiotensin-converting enzyme inhibition on infarct collagen deposition and remodelling during healing after transmural canine myocardial infarction.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Collagen; Dogs; Enalapril; Heart Ventr

1997
Effect of AT1 receptor blockade on cardiac collagen remodeling after myocardial infarction.
    Cardiovascular research, 1997, Volume: 35, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biomarkers; Blot

1997
The effect of delayed reperfusion following infarction in the rat on structural changes in viable myocardium.
    Cardiovascular research, 1997, Volume: 36, Issue:3

    Topics: Animals; Cell Nucleus; Cell Size; Hydroxyproline; Hypertrophy, Left Ventricular; Microscopy, Confoca

1997
[Activation of the cardiac angiotensin-converting enzyme after myocardial infarction and its role in ventricular remodeling].
    Arquivos brasileiros de cardiologia, 1997, Volume: 69, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopri

1997
Altered collagen concentration in mitral valve leaflets: biochemical and finite element analysis.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Animals; Biochemical Phenomena; Biochemistry; Chordae Tendineae; Collagen; Elasticity; Finite Elemen

1998
Reduced injury and scar in acute myocardial infarctions treated with human growth hormone.
    Japanese heart journal, 1998, Volume: 39, Issue:6

    Topics: Animals; Growth Hormone; Humans; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Rats; Rats

1998
Effects of lisinopril on experimental ischemia in rats. Influence of infarct size.
    Arquivos brasileiros de cardiologia, 1999, Volume: 73, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Fibrosis; Hydroxyproline; Lisinopri

1999
Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction.
    Journal of the American College of Cardiology, 2000, Volume: 36, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Carvedil

2000
Effects of losartan on ventricular remodeling in experimental infarction in rats.
    Arquivos brasileiros de cardiologia, 2000, Volume: 75, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Hydroxyproline; Losartan; Ma

2000
ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium-Transporting ATPases; Endothelin Recepto

2001
Heart regeneration in adult MRL mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Aug-14, Volume: 98, Issue:17

    Topics: Animals; Biomarkers; Cicatrix; Cold Temperature; Collagen; Collagen Type I; Collagen Type I, alpha 1

2001
Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction.
    Circulation, 2001, Oct-30, Volume: 104, Issue:18

    Topics: Animals; Collagen; Dilatation, Pathologic; Disease Models, Animal; Echocardiography; Enzyme Inhibito

2001
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril.
    Journal of the American College of Cardiology, 2002, May-01, Volume: 39, Issue:9

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers;

2002
[Myocardial infarct repair in the light of clinico-biochemical and morphological studies].
    Kardiologiia, 1977, Volume: 17, Issue:1

    Topics: Adult; Aged; alpha-Macroglobulins; Asparagine; Creatine Kinase; Erythrocyte Count; Female; Fibrinoge

1977
[Clinico-biochemical principles of healing of myocardial infarct].
    Kardiologiia, 1979, Volume: 19, Issue:5

    Topics: Adult; Aged; alpha-Macroglobulins; Erythrocyte Count; Female; Glycoproteins; Humans; Hydroxyproline;

1979
A study on myocardial fibrosis in myocardial infarction and in idiopathic cardiomyopathy: a measurement of hydroxyproline level in plasma and in myocardium.
    Japanese circulation journal, 1979, Volume: 43, Issue:10

    Topics: Animals; Cardiomyopathies; Dogs; Endomyocardial Fibrosis; Humans; Hydroxyproline; Myocardial Infarct

1979
Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction.
    The American journal of physiology, 1975, Volume: 228, Issue:1

    Topics: Animals; Collagen; Hydroxyproline; Isoproterenol; Male; Mixed Function Oxygenases; Myocardial Infarc

1975
Impact of increased infarct transmurality on remodeling and function during healing after anterior myocardial infarction in the dog.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:7

    Topics: Animals; Collagen; Coronary Circulation; Coronary Vessels; Dogs; Echocardiography; Electrocardiograp

1992
Effects of captopril on contractility after myocardial infarction: experimental observations.
    The American journal of cardiology, 1991, Nov-18, Volume: 68, Issue:14

    Topics: Animals; Blood Pressure; Blood Volume; Captopril; Cardiac Output, Low; Collagen; Hydroxyproline; Iso

1991
In vivo labeling studies on the biosynthesis and degradation of collagen in experimental myocardial infarction.
    Biochemistry international, 1991, Volume: 24, Issue:3

    Topics: Animals; Collagen; Female; Hydroxyproline; Isoproterenol; Myocardial Infarction; Proline; Radioactiv

1991
Tissue characterization of chronic myocardial infarction.
    Investigative radiology, 1990, Volume: 25, Issue:10

    Topics: Animals; Chronic Disease; Dogs; Echocardiography; Hydroxyproline; Magnetic Resonance Imaging; Myocar

1990
The effect of perfluorochemical fluosol-DA (20%) on myocardial infarct healing in the rabbit.
    The American journal of cardiovascular pathology, 1990, Volume: 3, Issue:1

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Combinations; Fluorocarbons; Foam Cells;

1990
[The diagnosis and reparative processes in a protracted course of myocardial infarct].
    Vrachebnoe delo, 1989, Issue:9

    Topics: Aged; Coronary Disease; Electrocardiography; Female; Hexoses; Humans; Hydroxyproline; Male; Middle A

1989
[Thrombocyte function and the repair of myocardial infarct].
    Vrachebnoe delo, 1989, Issue:1

    Topics: Aspirin; Blood Platelets; Dipyridamole; Female; Heart Function Tests; Humans; Hydroxyproline; Male;

1989
[Clinical regularities of myocardial infarction repair].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:4

    Topics: Glycoproteins; Hexoses; Humans; Hydroxyproline; Mucoproteins; Myocardial Infarction; Regeneration; R

1989
[Clinico-biochemical equivalent of stromal destruction in acute myocardial infarction].
    Kardiologiia, 1989, Volume: 29, Issue:5

    Topics: Collagen; Connective Tissue; Hexoses; Humans; Hydroxybutyrate Dehydrogenase; Hydroxyproline; Myocard

1989
Studies on collagen in the experimental myocardial infarction.
    Japanese circulation journal, 1985, Volume: 49, Issue:2

    Topics: Animals; Cell Movement; Collagen; Dogs; Fibroblasts; Hydroxyproline; Myocardial Infarction; Myocardi

1985
A biochemical method for the quantitation of myocardial scarring after experimental coronary artery occlusion.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:3

    Topics: Animals; Arteries; Chloramines; Collagen; Coronary Vessels; Disease Models, Animal; Heart Ventricles

1986
Effect of nitroglycerin and ibuprofen on left ventricular topography and rupture threshold during healing after myocardial infarction in the dog.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:4

    Topics: Animals; Dogs; Echocardiography; Heart; Heart Rupture; Hemodynamics; Hydroxyproline; Ibuprofen; Myoc

1988
[Quantitative integrated backscatter characteristics in the normal and infarcted canine myocardium].
    Journal of cardiography, 1986, Volume: 16, Issue:4

    Topics: Animals; Dogs; Hydroxyproline; Monitoring, Physiologic; Myocardial Infarction; Myocardium; Ultrasono

1986
Superoxide dismutase does not cause scar thinning after myocardial infarction.
    Journal of the American College of Cardiology, 1987, Volume: 9, Issue:4

    Topics: Animals; Cicatrix; Dogs; Echocardiography; Granulation Tissue; Hydroxyproline; Male; Myocardial Infa

1987
Left ventricular rupture threshold during the healing phase after myocardial infarction in the dog.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:3

    Topics: Animals; Coronary Vessels; Dogs; Heart Diseases; Heart Ventricles; Hemodynamics; Hydroxyproline; Lig

1987
The dynamics of healing processes in the heart muscle in acute myocardial infarction.
    Cor et vasa, 1987, Volume: 29, Issue:4

    Topics: Adult; Aged; Cicatrix; Collagen; Female; Humans; Hydroxyproline; Male; Middle Aged; Myocardial Infar

1987
Assessment of fibrosis in infarcted human hearts by analysis of ultrasonic backscatter.
    Circulation, 1985, Volume: 71, Issue:4

    Topics: Collagen; Humans; Hydroxyproline; Myocardial Infarction; Tissue Distribution; Ultrasonography

1985
Delayed effects of early infarct-limiting therapies on healing after myocardial infarction.
    Circulation, 1985, Volume: 72, Issue:4

    Topics: Animals; Collagen; Dogs; Epoprostenol; Hemodynamics; Hydroxyproline; Ibuprofen; Macrophages; Myocard

1985
Healing after myocardial infarction in the dog: changes in infarct hydroxyproline and topography.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Cicatrix; Dilatation, Pathologic; Dogs; Hydroxyproline; Myocar

1986
Effects of transient increased afterload during experimentally induced acute myocardial infarction in dogs.
    The American journal of cardiology, 1985, Feb-15, Volume: 55, Issue:5

    Topics: Animals; Dogs; Heart Ventricles; Hydroxyproline; Hypertension; Methoxamine; Myocardial Infarction; R

1985
Effect of ibuprofen on the healing phase of experimental myocardial infarction in the rat.
    The American journal of cardiology, 1985, Jun-01, Volume: 55, Issue:13 Pt 1

    Topics: Animals; Cell Count; Collagen; Hydroxyproline; Ibuprofen; Leukocytes; Male; Myocardial Infarction; R

1985
Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue.
    Circulation research, 1985, Volume: 57, Issue:4

    Topics: Animals; Arteries; Cicatrix; Collagen; Coronary Vessels; Desmosine; Elastin; Hydroxyproline; Ligatio

1985
[Urinary excretion of acid mucopolysaccharides and total hydroxyproline in myocardial infarction].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Nov-23, Volume: 23, Issue:52

    Topics: Adult; Aged; Female; Glycosaminoglycans; Humans; Hydroxyproline; Male; Middle Aged; Myocardial Infar

1968
Myocardial connective tissue metabolism in response to injury. Histological and chemical studies of mucopolysaccharide and collagen in rat hearts after isoproterenol-induced infaraction.
    Circulation research, 1969, Volume: 25, Issue:2

    Topics: Animals; Arteriosclerosis; Cicatrix; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosa

1969
Urinary elimination of acid mucopolysaccharides and total hydroxyproline in myocardial infarction.
    Polish medical journal, 1969, Volume: 8, Issue:5

    Topics: Adult; Aged; Female; Glycosaminoglycans; Humans; Hydroxyproline; Male; Middle Aged; Myocardial Infar

1969
[Early and late diagnostic biochemical indices in myocardial infarct].
    Kardiologiia, 1974, Volume: 14, Issue:2

    Topics: Arteriosclerosis; Clinical Enzyme Tests; Collagen; Coronary Disease; Creatine Kinase; Haptoglobins;

1974
[Basic indices of collagen metabolism in ischemic heart disease].
    Kardiologiia, 1972, Volume: 12, Issue:6

    Topics: Arteriosclerosis; Collagen; Coronary Disease; Humans; Hydroxyproline; Myocardial Infarction; Necrosi

1972
Biochemical changes in non-infarcted heart muscle following myocardial infarction.
    Journal of molecular and cellular cardiology, 1971, Volume: 2, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biopsy; Carbon Isotopes; Coronary Vessels; D

1971
Study on the idiopathic cardiomyopathy. Diagnostic value of the apexcardiogram, 131 Cs scintiscanning of the heart and plasma hydroxyproline.
    Japanese circulation journal, 1971, Volume: 35, Issue:7

    Topics: Adult; Amyl Nitrite; Autopsy; Cardiomyopathies; Cesium Isotopes; Child; Collagen; Collagen Diseases;

1971
Hydroxyproline in myocardial infarction and angina pectoris.
    Polish medical science and history bulletin, 1968, Volume: 11, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Female; Humans; Hydroxyproline; Male; Middle Aged; Myocardial Infarcti

1968
Hydroxyproline in myocardial infarction and angina pectoris.
    Polish medical journal, 1969, Volume: 8, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Female; Humans; Hydroxyproline; Male; Methods; Middle Aged; Myocardial

1969