hydroxyproline has been researched along with Cardiomegaly in 106 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 7.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| " We assessed the risk of ventricular arrhythmias in rats which subjected to chronic nandrolone plus high-intensity endurance exercise." | 7.83 | The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate. ( Abdollahi, F; Binayi, F; Joukar, S; Karimi, A; Masumi, Y; Najafipour, H, 2016) |
| "To study whether urotensin II (UII), a potent vasoconstrictive peptide, is involved in the development of cardiac hypertrophy and fibrogenesis of rats induced by isoproterenol (ISO)." | 7.74 | Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. ( Bu, DF; Li, YG; Liu, BG; Pang, YZ; Tan, XR; Tang, CS; Wang, DM; Wei, RH; Zhang, YG, 2007) |
| "The role of angiotensin II (ANG II) in the development of isoproterenol (Iso)-induced cardiac hypertrophy was examined in rats." | 7.69 | Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats. ( Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D, 1994) |
| " The effects of the ACE inhibitor, captopril, on collagen metabolism in spontaneously hypertensive rats (SHR) with cardiac hypertrophy was examined." | 7.68 | Angiotensin converting enzyme inhibitor, captopril, inhibits cardiac hypertrophy without changing collagen types and concentration in spontaneously hypertensive rats. ( Honda, M; Ishinaga, Y; Kuramochi, T; Kuzuo, H; Mansoor, AM; Morioka, S; Moriyama, K; Tanaka, K; Yamori, Y, 1993) |
| "To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 7.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
| "Cardiac hypertrophy was induced in adult female Wistar rats after 8 days of daily subcutaneous injections of isoproterenol (ISO)." | 7.67 | Regression of isoproterenol-induced cardiac hypertrophy. ( Tang, Q; Taylor, PB, 1984) |
| "The effects of long-term treatment with verapamil on blood pressure, cardiac hypertrophy and collagen content, collagen concentration and prolyl hydroxylase activity were studied in spontaneously hypertensive rats (SHR)." | 7.67 | Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats. ( Ruskoaho, HJ; Savolainen, ER, 1985) |
| "The development of cardiac hypertrophy was studied in adult female Wistar rats following daily subcutaneous injections of isoproterenol (ISO) (0." | 7.67 | Development of isoproterenol-induced cardiac hypertrophy. ( Tang, Q; Taylor, PB, 1984) |
| "To determine whether development and regression of cardiac hypertrophy are accompanied by changes in heart volume and to learn whether a change in heart volume is associated with changes in the myocardial connective tissue, cardiac hypertrophy was induced in rats by administration of thyroxine." | 7.65 | Heart volume and myocardial connective tissue during development and regression of thyroxine-induced cardiac hypertrophy in rats. ( Edgren, J; Lindy, S; Turto, H; von Knorring, J, 1976) |
| " We assessed the risk of ventricular arrhythmias in rats which subjected to chronic nandrolone plus high-intensity endurance exercise." | 3.83 | The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate. ( Abdollahi, F; Binayi, F; Joukar, S; Karimi, A; Masumi, Y; Najafipour, H, 2016) |
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 3.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| "Zofenopril partially prevented the increase in systolic blood pressure and cardiac hypertrophy induced by angiotensin II and avoided the increase in collagen deposition." | 3.83 | Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition. ( Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA, 2016) |
| "This study was carried out in order to investigate the effects of epigallocatechin gallate (EGCG) on myocardial fibrosis and cell proliferation in cardiac hypertrophy." | 3.75 | EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy. ( Gu, ZL; Guo, CY; Sheng, R; Xie, ML; Zhou, WX, 2009) |
| "To study whether urotensin II (UII), a potent vasoconstrictive peptide, is involved in the development of cardiac hypertrophy and fibrogenesis of rats induced by isoproterenol (ISO)." | 3.74 | Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. ( Bu, DF; Li, YG; Liu, BG; Pang, YZ; Tan, XR; Tang, CS; Wang, DM; Wei, RH; Zhang, YG, 2007) |
| "There were significant fibrosis and inflammatory infiltration in the myocardium and blood vessels, represented by higher hydroxyproline and collagen volume fraction, and a large amount of inflammatory cells in the tissues of SAD rats." | 3.72 | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. ( Chen, H; Shu, H; Su, DF; Xie, HH; Yuan, WJ; Zhang, C, 2003) |
| " This study aimed to analyze the effects of lisinopril on mortality rate, cardiac function, degree of cardiac hypertrophy and fibrosis in rats with different infarct sizes." | 3.70 | Effects of lisinopril on experimental ischemia in rats. Influence of infarct size. ( Matsubara, BB; Matsubara, LS; Paiva, SA; Spadaro, J; Tornero, MT; Zornoff, LA, 1999) |
| "The role of angiotensin II (ANG II) in the development of isoproterenol (Iso)-induced cardiac hypertrophy was examined in rats." | 3.69 | Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats. ( Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D, 1994) |
| " The effects of the ACE inhibitor, captopril, on collagen metabolism in spontaneously hypertensive rats (SHR) with cardiac hypertrophy was examined." | 3.68 | Angiotensin converting enzyme inhibitor, captopril, inhibits cardiac hypertrophy without changing collagen types and concentration in spontaneously hypertensive rats. ( Honda, M; Ishinaga, Y; Kuramochi, T; Kuzuo, H; Mansoor, AM; Morioka, S; Moriyama, K; Tanaka, K; Yamori, Y, 1993) |
| "To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 3.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
| " Therapy with captopril, an angiotensin-converting enzyme inhibitor that regresses cardiac hypertrophy, not only reduces the total amount of collagen but reverses the altered distribution of type I and type III collagen." | 3.68 | Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats. ( Mukherjee, D; Sen, S, 1990) |
| "Cardiac hypertrophy was induced in adult female Wistar rats after 8 days of daily subcutaneous injections of isoproterenol (ISO)." | 3.67 | Regression of isoproterenol-induced cardiac hypertrophy. ( Tang, Q; Taylor, PB, 1984) |
| "The effects of long-term treatment with verapamil on blood pressure, cardiac hypertrophy and collagen content, collagen concentration and prolyl hydroxylase activity were studied in spontaneously hypertensive rats (SHR)." | 3.67 | Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats. ( Ruskoaho, HJ; Savolainen, ER, 1985) |
| "The development of cardiac hypertrophy was studied in adult female Wistar rats following daily subcutaneous injections of isoproterenol (ISO) (0." | 3.67 | Development of isoproterenol-induced cardiac hypertrophy. ( Tang, Q; Taylor, PB, 1984) |
| " Hydroxyproline, used as an index of collagen content, was unaffected by postnatal cardiomegaly." | 3.66 | Postnatal carbon monoxide exposure: immediate and lasting effects in the rat. ( Baylerian, MS; Fanning, CM; Penney, DG; Thill, JE; Yedavally, S, 1982) |
| "Cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta." | 3.66 | The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. ( Cameron, AJ; Revis, NW, 1978) |
| " The total amounts of DNA and of hydroxyproline in the heart, which were used to evaluate the degree of connective tissue hyperplasia, increased only slightly (8% and 10%, respectively)." | 3.66 | Development and regression of exercise-induced cardiac hypertrophy in rats. ( Hammons, GT; Hickson, RC; Holoszy, JO, 1979) |
| "To determine whether development and regression of cardiac hypertrophy are accompanied by changes in heart volume and to learn whether a change in heart volume is associated with changes in the myocardial connective tissue, cardiac hypertrophy was induced in rats by administration of thyroxine." | 3.65 | Heart volume and myocardial connective tissue during development and regression of thyroxine-induced cardiac hypertrophy in rats. ( Edgren, J; Lindy, S; Turto, H; von Knorring, J, 1976) |
| " Cardiomegaly has been produced in rats by sideropenic anaemia, by isoprenaline or thyroxine or by the application of both drugs, by artificial increase in resistance to blood flow and by long-term adaptation to hypoxia and physical stress." | 3.65 | The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly. ( Bartosová, D; Chvapil, M; Korecký, B; Poupa, O; Rakusan, K; Turek, Z; Vízek, M, 1969) |
| "We examined the influence of chronic administration of nandrolone decanoate with low-intensity endurance swimming exercise on susceptibility to lethal ventricular arrhythmias in rat." | 1.43 | The Effects of Nandrolone Decanoate Along with Prolonged Low-Intensity Exercise on Susceptibility to Ventricular Arrhythmias. ( Abdollahi, F; Binayi, F; Joukar, S; Karimi, A; Masumi, Y; Najafipour, H, 2016) |
| "Endothelial dysfunction can lead to congestive heart failure and the activation of endothelial ATP-sensitive potassium (K(ATP)) channels may contribute to endothelial protection." | 1.40 | Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy. ( Cui, WY; Long, CL; Wang, H; Zhang, YF; Zhong, ML; Zhou, HM, 2014) |
| "EERS attenuates ventricular remodeling." | 1.38 | Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats. ( Chen, CX; Huang, XY; Li, YM; Liu, Y; Wu, XM; Zhang, XM, 2012) |
| "Sodium houttuyfonate can inhibit myocardial hypertrophy in mouse and rat models by restricting the activity of the sympathetic nervous system and decreasing the levels of angiotensin II and endothelin-1 in ventricular tissue." | 1.35 | Effect of sodium houttuyfonate on myocardial hypertrophy in mice and rats. ( Chen, CX; Gao, JP; Gu, WL; Lü, J; Wang, Y, 2009) |
| "The model of cardiac hypertrophy was produced by overloading pressure in rats." | 1.32 | Effect of crocetin on cardiac hypertrophy induced by overloading pressure in rats. ( Qian, ZY; Shen, XC, 2004) |
| "In hypertensive cardiac hypertrophy, myosin heavy chain isoform shift and reduction of SR protein levels are related to systolic and diastolic dysfunction, respectively." | 1.30 | Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy. ( Arnold, G; Böhm, M; Flesch, M; Hirth-Dietrich, C; Paul, M; Pinto, Y; Rosenkranz, S; Schiffer, F; Zolk, O, 1997) |
| "At this age, hypertension has already caused a significant increase in the ratio of the ventricular mass to body weight (mg/g) in hypertensive animals (SHR: 5." | 1.28 | [Changes in myocardial collagen in spontaneously hypertensive rats (SHR)]. ( Garbisa, S; Guardiano, M; Onisto, M; Pauletto, P; Pessina, AC; Santipolo, N; Spina, M, 1991) |
| "Thus, in pressure-overloaded cardiac hypertrophy with coronary hypertension, coronary reserve seems to be determined by medial hypertrophy independently of collagen deposition, but collagen deposition plays an important role in the reversal of vasodilator reserve after relief of the overload." | 1.28 | Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy. ( Isoyama, S; Ito, N; Satoh, K; Takishima, T, 1992) |
| " In this study, we investigated the effect of chronic administration of carteolol (4 mg/kg/day p." | 1.28 | Effect of long-term treatment with beta-blocker on cardiac hypertrophy in SHR. ( Ieki, K; Kojima, M; Komuro, I; Seko, Y; Sugiyama, T; Takaku, F; Tsuchimochi, H; Yamaoki, K; Yazaki, Y; Yoshizumi, M, 1989) |
| "Lung hydroxyproline content was measured as an index of interstitial fibrosis." | 1.28 | Monocrotaline-induced cardiopulmonary injury in rats. Modification by the neutrophil elastase inhibitor SC39026. ( Hinz, JM; Molteni, A; Ts'ao, CH; Ward, WF, 1989) |
| "Hydroxyproline concentration was inversely related to myosin concentration in both LV pressure-overload models and increased with the severity of hypertrophy." | 1.27 | Myocardial changes during the progression of left ventricular pressure-overload by renal hypertension or aortic constriction: myosin, myosin ATPase and collagen. ( Bailey, BK; Bassett, AL; Fieber, LA; Kimura, S; Kozlovskis, PL; Myerburg, RJ; Pruitt, DK; Smets, MJ, 1987) |
| "The hydroxyproline concentration was increased in all parts of the hypertrophied myocardium in spontaneously hypertensive rats." | 1.26 | Collagen content in different areas of normal and hypertrophied rat myocardium. ( Medugorac, I, 1980) |
| "Biochemical and physical parameters of cardiac hypertrophy accompanying hypertension were studied in water deprived versus non-deprived immature spontaneously hypertensive rats (SHR) and their normotensive progenitor strain, Wistar Kyoto (WKY)." | 1.26 | Reduced left ventricular hypertrophy following long-term water deprivation in the young spontaneously hypertensive rat. ( Brackett, DJ; Schaefer, CF; Tompkins, P; Wilson, MF, 1980) |
| "Digitoxin treatment did not alter peak flow velocity or flow acceleration, but did significantly increase isovolumic (dP/dt)P-1." | 1.26 | Effect of prophylactic digitalization on the development of myocardial hypertrophy. ( Arcilla, RA; Cutilletta, AF; Rudnik, M; Straube, R, 1977) |
| "The dipyridamole treatment had no effect on the increase in systolic pressure, the contractility index of the aorta-stenosed animals and heart rate." | 1.25 | [Variation of mechanical and biochemical parameters of pressure-loaded rabbit hearts following chronic administration of dipyridamole]. ( Förster, W; Ritter, C; Weiss, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (59.43) | 18.7374 |
| 1990's | 18 (16.98) | 18.2507 |
| 2000's | 14 (13.21) | 29.6817 |
| 2010's | 10 (9.43) | 24.3611 |
| 2020's | 1 (0.94) | 2.80 |
| Authors | Studies |
|---|---|
| Potnuri, AG | 1 |
| Reddy, KP | 1 |
| Suresh, P | 1 |
| Husain, GM | 1 |
| Kazmi, MH | 1 |
| Harishankar, N | 1 |
| Zhou, HM | 1 |
| Zhong, ML | 1 |
| Zhang, YF | 1 |
| Cui, WY | 1 |
| Long, CL | 1 |
| Wang, H | 1 |
| Binayi, F | 2 |
| Joukar, S | 2 |
| Najafipour, H | 2 |
| Karimi, A | 3 |
| Abdollahi, F | 2 |
| Masumi, Y | 2 |
| Zhao, LM | 1 |
| Wang, LP | 1 |
| Wang, HF | 1 |
| Ma, XZ | 1 |
| Zhou, DX | 1 |
| Deng, XL | 1 |
| Lu, J | 2 |
| Liu, F | 1 |
| Liu, D | 1 |
| Du, H | 1 |
| Hao, J | 1 |
| Yang, X | 1 |
| Cui, W | 1 |
| Gómez-Roso, M | 1 |
| Montero, MJ | 1 |
| Carrón, R | 1 |
| Sevilla, MA | 1 |
| Li, C | 1 |
| Han, R | 1 |
| Kang, L | 1 |
| Wang, J | 1 |
| Gao, Y | 1 |
| Li, Y | 1 |
| He, J | 1 |
| Tian, J | 1 |
| Sheng, R | 1 |
| Gu, ZL | 1 |
| Xie, ML | 1 |
| Zhou, WX | 1 |
| Guo, CY | 1 |
| Gao, JP | 1 |
| Chen, CX | 2 |
| Wang, Y | 2 |
| Gu, WL | 1 |
| Soci, UP | 1 |
| Fernandes, T | 1 |
| Hashimoto, NY | 2 |
| Mota, GF | 1 |
| Amadeu, MA | 1 |
| Rosa, KT | 1 |
| Irigoyen, MC | 1 |
| Phillips, MI | 1 |
| Oliveira, EM | 2 |
| Huang, XY | 1 |
| Zhang, XM | 1 |
| Liu, Y | 1 |
| Wu, XM | 1 |
| Li, YM | 1 |
| Maulik, SK | 1 |
| Prabhakar, P | 1 |
| Dinda, AK | 1 |
| Seth, S | 1 |
| NAKASHIMA, T | 1 |
| IWANAGA, Y | 1 |
| NAKAURA, Y | 1 |
| KORECKY, B | 2 |
| RAKUSAN, K | 2 |
| POUPA, O | 2 |
| WEGELIUS, O | 1 |
| Zhang, C | 1 |
| Chen, H | 1 |
| Xie, HH | 1 |
| Shu, H | 1 |
| Yuan, WJ | 1 |
| Su, DF | 1 |
| Ahn, J | 1 |
| Varagic, J | 1 |
| Slama, M | 1 |
| Susic, D | 1 |
| Frohlich, ED | 1 |
| Shen, XC | 1 |
| Qian, ZY | 1 |
| Turcani, M | 2 |
| Thormaehlen, D | 1 |
| Rupp, H | 2 |
| Zhang, J | 1 |
| Qi, YF | 1 |
| Geng, B | 1 |
| Pan, CS | 1 |
| Zhao, J | 1 |
| Chen, L | 1 |
| Yang, J | 1 |
| Chang, JK | 1 |
| Tang, CS | 2 |
| Zhang, YG | 1 |
| Li, YG | 1 |
| Liu, BG | 1 |
| Wei, RH | 1 |
| Wang, DM | 1 |
| Tan, XR | 1 |
| Bu, DF | 1 |
| Pang, YZ | 1 |
| Rocha, FL | 1 |
| Carmo, EC | 1 |
| Roque, FR | 1 |
| Rossoni, LV | 1 |
| Frimm, C | 1 |
| Anéas, I | 1 |
| Negrão, CE | 1 |
| Krieger, JE | 1 |
| Zhai, Y | 1 |
| Gao, X | 1 |
| Wu, Q | 1 |
| Peng, L | 1 |
| Lin, J | 1 |
| Zuo, Z | 1 |
| Sen, S | 6 |
| Tarazi, RC | 3 |
| Bumpus, FM | 3 |
| Lafranconi, WM | 1 |
| Duhamel, RC | 1 |
| Brendel, K | 1 |
| Huxtable, RJ | 1 |
| Taylor, PB | 2 |
| Tang, Q | 2 |
| Cooper, G | 2 |
| Tomanek, RJ | 3 |
| Dawson, R | 1 |
| Milne, G | 1 |
| Williams, RB | 2 |
| Hickson, RC | 2 |
| Galassi, TM | 1 |
| Dougherty, KA | 1 |
| McKenzie, JC | 1 |
| Klein, RM | 1 |
| Williams, JF | 3 |
| Mathew, B | 2 |
| Hern, DL | 2 |
| Potter, RD | 2 |
| Deiss, WP | 3 |
| Marino, TA | 1 |
| Genovese, A | 2 |
| Chiariello, M | 1 |
| Bozzaotre, M | 1 |
| Latte, S | 1 |
| De Alfieri, W | 1 |
| Condorelli, M | 2 |
| Penney, DG | 2 |
| Baylerian, MS | 1 |
| Thill, JE | 1 |
| Fanning, CM | 1 |
| Yedavally, S | 1 |
| Tompkins, P | 1 |
| Wilson, MF | 1 |
| Brackett, DJ | 1 |
| Schaefer, CF | 1 |
| Carey, RA | 1 |
| Natarjan, G | 1 |
| Bove, AA | 1 |
| Santamore, WP | 1 |
| Spann, JF | 1 |
| Medugorac, I | 3 |
| Kunz, J | 1 |
| Braselmann, H | 1 |
| Gottschalk, J | 1 |
| Kreher, C | 1 |
| Pieper, KS | 1 |
| Schraeger, JA | 1 |
| Canby, CA | 1 |
| Rongish, BJ | 1 |
| Kawai, M | 1 |
| Golomb, E | 1 |
| Abassi, ZA | 1 |
| Cuda, G | 1 |
| Stylianou, M | 1 |
| Panchal, VR | 1 |
| Trachewsky, D | 1 |
| Keiser, HR | 1 |
| Conrad, CH | 1 |
| Brooks, WW | 2 |
| Hayes, JA | 1 |
| Robinson, KG | 1 |
| Bing, OH | 3 |
| Takeo, S | 1 |
| Tanonaka, K | 1 |
| Aoki, M | 1 |
| Nakai, Y | 1 |
| Sanbe, A | 1 |
| Shizume, Y | 1 |
| Tanaka, C | 1 |
| Miyake, K | 1 |
| Hirai, K | 1 |
| Ueda, N | 1 |
| Kuzuo, H | 1 |
| Honda, M | 1 |
| Ishinaga, Y | 1 |
| Morioka, S | 1 |
| Tanaka, K | 1 |
| Kuramochi, T | 1 |
| Mansoor, AM | 1 |
| Yamori, Y | 1 |
| Moriyama, K | 1 |
| Flesch, M | 1 |
| Schiffer, F | 1 |
| Zolk, O | 1 |
| Pinto, Y | 1 |
| Rosenkranz, S | 1 |
| Hirth-Dietrich, C | 1 |
| Arnold, G | 1 |
| Paul, M | 1 |
| Böhm, M | 1 |
| Yang, CM | 1 |
| Kandaswamy, V | 1 |
| Young, D | 1 |
| Perhonen, M | 1 |
| Wang, W | 1 |
| Han, X | 1 |
| Ruskoaho, H | 1 |
| Takala, TE | 1 |
| Umemura, K | 1 |
| Kikuchi, S | 1 |
| Suzuki, Y | 1 |
| Nakashima, M | 1 |
| Wang, DQ | 1 |
| Kakizoe, E | 1 |
| Kobayashi, Y | 1 |
| Shimoura, K | 1 |
| Okunishi, H | 1 |
| Zornoff, LA | 1 |
| Matsubara, BB | 1 |
| Matsubara, LS | 1 |
| Paiva, SA | 1 |
| Tornero, MT | 1 |
| Spadaro, J | 1 |
| Kim, HE | 1 |
| Dalal, SS | 1 |
| Young, E | 1 |
| Legato, MJ | 1 |
| Weisfeldt, ML | 1 |
| D'Armiento, J | 1 |
| Klinger, JR | 1 |
| Warburton, RR | 1 |
| Pietras, L | 1 |
| Oliver, P | 1 |
| Fox, J | 1 |
| Smithies, O | 1 |
| Hill, NS | 1 |
| Stroud, JD | 1 |
| Baicu, CF | 1 |
| Barnes, MA | 1 |
| Spinale, FG | 1 |
| Zile, MR | 1 |
| Cutilletta, AF | 2 |
| Dowell, RT | 3 |
| Rudnik, M | 2 |
| Arcilla, RA | 2 |
| Zak, R | 4 |
| Leclercq, JF | 2 |
| Swynghedauw, B | 2 |
| Bouveret, P | 1 |
| Faucomprez, C | 1 |
| Piguet, V | 1 |
| Tipton, CM | 1 |
| Kiiskinen, A | 1 |
| Heikkinen, E | 1 |
| Ritter, C | 1 |
| Weiss, M | 1 |
| Förster, W | 1 |
| Edgren, J | 1 |
| von Knorring, J | 1 |
| Lindy, S | 2 |
| Turto, H | 2 |
| Jacob, R | 1 |
| Straube, R | 1 |
| Caspari, PG | 1 |
| Newcomb, M | 1 |
| Gibson, K | 1 |
| Harris, P | 1 |
| Frederiksen, DW | 1 |
| Hoffnung, JM | 1 |
| Frederiksen, RT | 1 |
| Fanburg, BL | 2 |
| Matsushita, S | 2 |
| Revis, NW | 1 |
| Cameron, AJ | 1 |
| Lamers, JM | 1 |
| Stinis, JT | 1 |
| Kort, WJ | 1 |
| Hülsmann, WC | 1 |
| Hammons, GT | 1 |
| Holoszy, JO | 1 |
| Isoyama, S | 1 |
| Ito, N | 1 |
| Satoh, K | 1 |
| Takishima, T | 1 |
| Randhawa, AK | 1 |
| Singal, PK | 1 |
| Contard, F | 1 |
| Koteliansky, V | 1 |
| Marotte, F | 1 |
| Dubus, I | 1 |
| Rappaport, L | 1 |
| Samuel, JL | 1 |
| Grover-McKay, M | 1 |
| Scholz, TD | 1 |
| Burns, TL | 1 |
| Skorton, DJ | 1 |
| Takemori, E | 1 |
| Hasegawa, Y | 1 |
| Katahira, J | 1 |
| Nakao, K | 1 |
| Inukai, T | 1 |
| Santipolo, N | 1 |
| Guardiano, M | 1 |
| Pessina, AC | 1 |
| Pauletto, P | 1 |
| Onisto, M | 1 |
| Garbisa, S | 1 |
| Spina, M | 1 |
| Mukherjee, D | 1 |
| Accinni, A | 1 |
| Spadaro, G | 1 |
| Quattrin, S | 1 |
| Motz, W | 1 |
| Strauer, BE | 1 |
| Imataka, K | 1 |
| Naito, S | 1 |
| Seko, Y | 2 |
| Fujii, J | 1 |
| Molteni, A | 1 |
| Ward, WF | 1 |
| Ts'ao, CH | 1 |
| Hinz, JM | 1 |
| Ieki, K | 1 |
| Yazaki, Y | 1 |
| Yamaoki, K | 1 |
| Tsuchimochi, H | 1 |
| Yoshizumi, M | 1 |
| Komuro, I | 1 |
| Sugiyama, T | 1 |
| Takaku, F | 1 |
| Kojima, M | 1 |
| Zlatos, L | 1 |
| Holzerová, J | 1 |
| Kvaszová, E | 1 |
| Danihel, L | 1 |
| Kozlovskis, PL | 1 |
| Fieber, LA | 1 |
| Pruitt, DK | 1 |
| Bailey, BK | 1 |
| Smets, MJ | 1 |
| Bassett, AL | 1 |
| Kimura, S | 1 |
| Myerburg, RJ | 1 |
| Davidson, SB | 1 |
| Gargulinski, RB | 1 |
| Caldwell-Ayre, TM | 1 |
| Ruskoaho, HJ | 1 |
| Savolainen, ER | 1 |
| Jansen, HH | 1 |
| Chvapil, M | 3 |
| Hurych, J | 1 |
| Ehrlichová, E | 1 |
| Layman, TE | 1 |
| Bartosová, D | 1 |
| Turek, Z | 1 |
| Vízek, M | 1 |
| Grove, D | 1 |
| Nair, KG | 1 |
| Aschenbrenner, V | 3 |
| Levine, HJ | 1 |
| Skosey, JL | 2 |
| Martin, AF | 1 |
| Rabinowitz, M | 2 |
| Alinder, I | 1 |
| Boström, H | 1 |
| McGrath, JJ | 1 |
| Procházka, J | 1 |
| Pelouch, V | 1 |
| Ostádal, B | 1 |
| Mowery, MB | 1 |
| Lindsay, HA | 1 |
| Bartos, D | 1 |
| Bartos, F | 1 |
| Berjal, G | 1 |
| Durand, M | 1 |
| Hatt, PY | 1 |
| Aschienbrenner, V | 1 |
| Uitto, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study of Pirfenidone in the Treatment of Myocardial Fibrosis After Acute Myocardial Infarction: a Phase II Prospective, Randomized, Double-blind，Placebo Controlled Clinical Trial[NCT05531955] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-08-05 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydroxyproline and Cardiomegaly
| Article | Year |
|---|---|
Idiopathic cystic medionecrosis and aneurysmal dilatation of the ascending aorta.
Topics: Adult; Aged; Angiography; Aorta, Thoracic; Aortic Aneurysm; Aortic Valve Insufficiency; Cardiac Cath | 1968 |
105 other studies available for hydroxyproline and Cardiomegaly
| Article | Year |
|---|---|
Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat.
Topics: Adiposity; Animals; Antipsychotic Agents; Cardiomegaly; Disease Models, Animal; Female; Haloperidol; | 2021 |
Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy.
Topics: Administration, Oral; Allyl Compounds; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relation | 2014 |
The Effects of Nandrolone Decanoate Along with Prolonged Low-Intensity Exercise on Susceptibility to Ventricular Arrhythmias.
Topics: Aconitine; Anabolic Agents; Animals; Body Weight; Cardiomegaly; Electrocardiography; Glutathione Per | 2016 |
The role of KCa3.1 channels in cardiac fibrosis induced by pressure overload in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Aorta, Abdominal; Blood Pressure; | 2015 |
The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Body Weight; Cardiomegaly; Electrocardiography; Gluta | 2016 |
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats.
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Cros | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, T | 2016 |
Pirfenidone controls the feedback loop of the AT1R/p38 MAPK/renin-angiotensin system axis by regulating liver X receptor-α in myocardial infarction-induced cardiac fibrosis.
Topics: Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Collagen Type III; Feedback, Physiological; | 2017 |
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; C | 2009 |
Effect of sodium houttuyfonate on myocardial hypertrophy in mice and rats.
Topics: Alkanes; Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic AMP; Dose-Response Relationship, D | 2009 |
MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Citrate (si)-Synthase; Female; Genetic Markers; Heart Ventric | 2011 |
Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Chemical Analysis; Captopril; Cardiomegaly | 2012 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibr | 2012 |
PATHOLOGIC STUDY OF HYPERTENSIVE HEART.
Topics: Adolescent; Amino Acids; Body Weight; Cardiomegaly; Child; Collagen; Coronary Disease; Geriatrics; H | 1964 |
THE WEIGHT AND CHEMICAL COMPOSITION OF THE HEART OF RATS SUFFERING FROM SIDEROPENIC ANAEMIA IN THE EARLY POSTNATAL PERIOD.
Topics: Anemia; Anemia, Hypochromic; Body Weight; Cardiomegaly; Chemical Phenomena; Chemistry; Chlorides; He | 1964 |
[THE EFFECT OF CARDIOSCLEROSIS ON THE HYDROXYPROLINE AND HEXOSAMINE CONTENT OF THE MYOCARDIUM].
Topics: Cardiomegaly; Coronary Disease; Hexosamines; Humans; Hydroxyproline; Myocardium; Rheumatic Heart Dis | 1964 |
Inflammation is involved in the organ damage induced by sinoaortic denervation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta; Blood Vessels; Cardiomegaly; | 2003 |
Cardiac structural and functional responses to salt loading in SHR.
Topics: Aging; Animals; Blood Pressure; Cardiomegaly; Echocardiography; Fibrosis; Heart; Heart Failure; Hydr | 2004 |
Effect of crocetin on cardiac hypertrophy induced by overloading pressure in rats.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Cardiomegaly; Carotenoids; Hydroxyproline; Male; Matrix Metalloprotei | 2004 |
Tedisamil attenuates foetal transformation of myosin in the hypertrophied rat myocardium.
Topics: Animals; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic; Cardiomegaly; Cardiot | 2004 |
Effect of relaxin on myocardial ischemia injury induced by isoproterenol.
Topics: Animals; Cardiomegaly; Creatine Kinase; Disease Models, Animal; Endothelins; Gene Expression; Heart; | 2005 |
Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Proliferation; Collagen; Fibroblasts; Fibrosis; Hydroxyp | 2007 |
Anabolic steroids induce cardiac renin-angiotensin system and impair the beneficial effects of aerobic training in rats.
Topics: Anabolic Agents; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; C | 2007 |
Fluvastatin decreases cardiac fibrosis possibly through regulation of TGF-beta(1)/Smad 7 expression in the spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Blotting, Western; Cardiomegaly; Cholesterol; Collagen; Dose-Response Relat | 2008 |
Reversal of cardiac hypertrophy in renal hypertensive rats: medical vs. surgical therapy.
Topics: Animals; Blood Pressure; Captopril; Cardiomegaly; DNA; Hydroxyproline; Hypertension, Renal; Male; My | 1981 |
Differentiation of the cardiac and pulmonary toxicity of monocrotaline, a pyrrolizidine alkaloid.
Topics: Animals; Cardiomegaly; Collagen; DNA; Female; Hydroxyproline; Lipid Metabolism; Lung Diseases; Male; | 1984 |
Development of isoproterenol-induced cardiac hypertrophy.
Topics: Animals; Body Water; Body Weight; Cardiomegaly; DNA; Female; Half-Life; Hemodynamics; Hydroxyproline | 1984 |
Regression of isoproterenol-induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; DNA; DNA-Directed RNA Polymerases; Female; Hydroxyproline; Isoproterenol; Myo | 1984 |
Load regulation of the structure, composition, and function of mammalian myocardium.
Topics: Animals; Blood Flow Velocity; Cardiomegaly; Catecholamines; Cats; Chordae Tendineae; Coronary Circul | 1982 |
Changes in the collagen of rat heart in copper-deficiency-induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Collagen; Copper; Electrophoresis, Polyacrylamide Gel; Hydroxyproline; Myocar | 1982 |
Repeated development and regression of exercise-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Citrate (si)-Synthase; Female; Hydroxyproline; Myocardium; Myoglobin; Physica | 1983 |
Protein synthesis in the rat pulmonary trunk during the early development of hypoxia-induced pulmonary hypertension.
Topics: Animals; Cardiomegaly; Collagen; Glycine; Hematocrit; Hydroxyproline; Hypertension, Pulmonary; Hypox | 1983 |
Myocardial hydroxyproline and mechanical response to prolonged pressure loading followed by unloading in the cat.
Topics: Animals; Cardiomegaly; Cats; Elasticity; Heart; Hydroxyproline; Ligation; Myocardium; Pressure; Pulm | 1983 |
Complete reversibility of cat right ventricular chronic progressive pressure overload.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Cats; Chronic Disease; Hydroxyproline; Liver; My | 1984 |
Adrenergic activity as a modulating factor in the genesis of myocardial hypertrophy in the rat.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hydroxyproline; Isoproterenol; Male; | 1984 |
Postnatal carbon monoxide exposure: immediate and lasting effects in the rat.
Topics: Animals; Animals, Newborn; Carbon Monoxide Poisoning; Cardiomegaly; Cytochrome c Group; DNA; Female; | 1982 |
Reduced left ventricular hypertrophy following long-term water deprivation in the young spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; DNA; Female; Hydroxyproline; Hypertension; Male; Myocardium; | 1980 |
Elevated collagen content in volume overload induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cats; Collagen; Hydroxyproline; Myocardium | 1980 |
Myocardial collagen in different forms of heart hypertrophy in the rat.
Topics: Animals; Aortic Valve Stenosis; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertension, | 1980 |
Collagen content in different areas of normal and hypertrophied rat myocardium.
Topics: Animals; Cardiomegaly; Collagen; Heart Ventricles; Hydroxyproline; Hypertension; Myocardium; Rats | 1980 |
The myocardial collagenous connective tissue in experimental cardiac hypertrophy induced by swimming exercise and hypertension.
Topics: Animals; Autoradiography; Cardiomegaly; Collagen; Connective Tissue; Hydroxyproline; Hypertension; M | 1981 |
Hydroxyproline and passive stiffness of pressure-induced hypertrophied kitten myocardium.
Topics: Animals; Blood Pressure; Cardiomegaly; Cats; Elasticity; Heart; Heart Ventricles; Hydroxyproline; My | 1982 |
Normal left ventricular diastolic compliance after regression of hypertrophy.
Topics: Aging; Animals; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Collagen; Diastole; Elasticity | 1994 |
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardi | 1994 |
Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat.
Topics: Aging; Animals; Cardiomegaly; Endomyocardial Fibrosis; Heart Failure; Hydroxyproline; Hypertension; | 1995 |
In vivo profile of myocardial energy metabolism of pressure-overloaded rat.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Collagen; Energy Metabolism; Hemodyna | 1993 |
Angiotensin converting enzyme inhibitor, captopril, inhibits cardiac hypertrophy without changing collagen types and concentration in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomegaly; Collagen | 1993 |
Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium-Binding Proteins; Calcium-Transporti | 1997 |
Changes in collagen phenotypes during progression and regression of cardiac hypertrophy.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Captopril; Cardiomegal | 1997 |
Right ventricular collagen type III and IV gene expression increases during early phases of endurance training in hypobaric hypoxic condition.
Topics: Animals; Atmosphere Exposure Chambers; Atmospheric Pressure; Blotting, Northern; Cardiomegaly; Colla | 1997 |
Inhibitory effect of tranilast on hypertrophic collagen production in the spontaneously hypertensive rat heart.
Topics: Animals; Anti-Allergic Agents; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Collagen; | 1998 |
Differential suppression of pressure-overload cardiac and aortic hypertrophy in rats by angiotensin-converting enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Aortic Diseases; Blood Pressure | 1999 |
Effects of lisinopril on experimental ischemia in rats. Influence of infarct size.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Fibrosis; Hydroxyproline; Lisinopri | 1999 |
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction.
Topics: Age Factors; Animals; Cardiomegaly; Collagen; Diastole; Extracellular Matrix; Gene Expression; Heart | 2000 |
Bradykinin (B2) independent effect of captopril on the development of pressure overload cardiac hypertrophy.
Topics: Animals; Aorta, Thoracic; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cardi | 2000 |
Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy.
Topics: Animals; Atrial Natriuretic Factor; Cardiomegaly; Carotid Arteries; Disease Progression; Guanylate C | 2002 |
Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment.
Topics: Animals; Cardiomegaly; Cats; Collagen; Constriction; Elasticity; Enzyme Activation; Fibrinolysin; Hy | 2002 |
Regression of myocardial hypertrophy. I. Experimental model, changes in heart weight, nucleic acids and collagen.
Topics: Animals; Body Weight; Cardiomegaly; Collagen; DNA; Female; Hydroxyproline; Models, Biological; Myoca | 1975 |
Myofibrillar ATPase, DNA and hydroxyproline content of human hypertrophied heart.
Topics: Adenosine Triphosphatases; Aged; Cardiomegaly; DNA; Humans; Hydroxyproline; Middle Aged; Myocardium; | 1976 |
Biochemical changes associated with development and reversal of cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Methyldopa; Myocardium; Myosins; Organ Siz | 1976 |
Cardiac enlargement mechanisms with exercise training and pressure overload.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Desoxycorticosterone; DNA; Heart; Hydroxyproline | 1976 |
Physical training and connective tissues in young mice-heart.
Topics: Animals; Cardiomegaly; Connective Tissue; Hexosamines; Hydroxyproline; Male; Mice; Myocardium; Nitro | 1976 |
[Variation of mechanical and biochemical parameters of pressure-loaded rabbit hearts following chronic administration of dipyridamole].
Topics: Animals; Cardiomegaly; Dipyridamole; Heart; Hemodynamics; Hydroxyproline; Myocardium; Rabbits | 1975 |
Heart volume and myocardial connective tissue during development and regression of thyroxine-induced cardiac hypertrophy in rats.
Topics: Animals; Body Weight; Cardiac Volume; Cardiomegaly; Collagen; DNA; Heart; Heart Ventricles; Hydroxyp | 1976 |
Concentration and adenosinetriphosphatase activity on left ventricular actomyosin in Goldblatt rats during the compensatory stage of hypertrophy.
Topics: Actomyosin; Adenosine Triphosphatases; Animals; Body Weight; Cardiomegaly; Hydroxyproline; Kinetics; | 1976 |
Hemodynamic factors and vascular density as potential determinants of blood flow in hypertrophied rat heart.
Topics: Alkaline Phosphatase; Animals; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; | 1977 |
Effect of prophylactic digitalization on the development of myocardial hypertrophy.
Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Coronary Circulation; Digitoxin; Female; Hea | 1977 |
Cardiac hypertrophy and antihypertensive therapy.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Male; Methyldopa; Minoxidil; Myocardium; P | 1977 |
Collagen in the normal and hypertrophied human ventricle.
Topics: Adolescent; Adult; Aged; Aging; Aortic Valve Stenosis; Cardiomegaly; Collagen; Heart Ventricles; Hum | 1977 |
The structural proteins of normal and diseased human myocardium.
Topics: Actomyosin; Adult; Aged; Animals; Cardiomegaly; Collagen; Coronary Disease; Disease Models, Animal; | 1978 |
The effect of lathyrogen beta-amino proprionitrile (BAPN) on the mechanical properties of experimentally hypertrophied rat cardiac muscle.
Topics: Aminopropionitrile; Animals; Body Weight; Cardiomegaly; Heart Ventricles; Hydroxyproline; Male; Myoc | 1978 |
The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits.
Topics: Animals; Aortic Coarctation; Cardiomegaly; Collagen; Hydroxyproline; Isoenzymes; Isoproterenol; L-La | 1978 |
Biochemical studies on the sarcolemmal function in the hypertrophied rabbit heart.
Topics: 4-Nitrophenylphosphatase; Adenylyl Cyclases; Animals; Aorta; Cardiomegaly; Constriction; DNA; Female | 1978 |
Development and regression of exercise-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Connective Tissue; Cytochrome c Group; DNA; Female; Heart; Hydroxyproline; Hy | 1979 |
Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy.
Topics: Aminopropionitrile; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Body Weight; Carbon Diox | 1992 |
Pressure overload-induced cardiac hypertrophy with and without dilation.
Topics: Animals; Aorta; Biopsy; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Disease Models, Animal; | 1992 |
Specific alterations in the distribution of extracellular matrix components within rat myocardium during the development of pressure overload.
Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Extracellular Matrix Proteins; Female; Fibro | 1991 |
Myocardial collagen concentration and nuclear magnetic resonance relaxation times in the spontaneously hypertensive rat.
Topics: Aging; Animals; Body Water; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Magnetic Resonance | 1991 |
Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biomarkers; Blood Pres | 1991 |
[Changes in myocardial collagen in spontaneously hypertensive rats (SHR)].
Topics: Age Factors; Animals; Cardiomegaly; Collagen; Densitometry; Elasticity; Electrophoresis; Hydroxyprol | 1991 |
Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Animals; Captopril; Cardiomegaly; Collagen; Cyanogen Bromide; Female; Hydroxyproline; H | 1990 |
Myocardial hypertrophy in rats exposed to simulated high altitude.
Topics: Altitude; Animals; Atmospheric Pressure; Cardiomegaly; Hemodynamics; Hydroxyproline; Hypoxia; In Vit | 1985 |
Left ventricular function and collagen content after regression of hypertensive hypertrophy.
Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Hypertension; Nifedipine; Rats; Rats, Inbred | 1989 |
Hydroxyproline in all parts of the rabbit heart in hypertension and in its reversal.
Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Hydroxyproline; Hypertension, Renovascular; Male; M | 1989 |
Monocrotaline-induced cardiopulmonary injury in rats. Modification by the neutrophil elastase inhibitor SC39026.
Topics: Animals; Cardiomegaly; Chlorobenzoates; Epoprostenol; Hydroxyproline; Lung Diseases; Male; Monocrota | 1989 |
Effect of long-term treatment with beta-blocker on cardiac hypertrophy in SHR.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Carteolol; Hydroxyproline; Male; Myosins; Propra | 1989 |
[The effect of chronic sympathectomy on the concentration and total levels of DNA and hydroxyproline in the myocardium of young rats with increased cardiac load].
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Cardiomegaly; DNA; Heart; Hydroxyproline; Myoc | 1986 |
Myocardial changes during the progression of left ventricular pressure-overload by renal hypertension or aortic constriction: myosin, myosin ATPase and collagen.
Topics: Adenosine Triphosphatases; Animals; Aortic Diseases; Arterial Occlusive Diseases; Blood Pressure; Bo | 1987 |
Heart and lung hypertrophy, changes in blood volume, hematocrit and plasma renin activity in rats chronically exposed to increasing carbon monoxide concentrations.
Topics: Animals; Blood Volume; Body Fluids; Carbon Monoxide Poisoning; Cardiomegaly; Hematocrit; Hydroxyprol | 1988 |
The connective tissue and contractile response of the myocardium to the development and regression of hypertrophy.
Topics: Animals; Cardiomegaly; Cats; Connective Tissue; Heart Ventricles; Hydroxyproline; Myocardial Contrac | 1989 |
Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Female; Heart; Hydroxyproline; Hypertension; | 1985 |
[Quantitative connective tissue conditions in ventricle walls of insufficient hearts, demonstrated by the example of hydroxyproline determination].
Topics: Cardiomegaly; Connective Tissue; Heart; Heart Failure; Heart Ventricles; Humans; Hydroxyproline; Myo | 1967 |
[The influence of iron and copper on the formation of collagen and non-collagen proteins].
Topics: Animals; Carbon Isotopes; Cardiomegaly; Copper; Granulation Tissue; Hydroxyproline; Iron; Lysine; My | 1967 |
The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly.
Topics: Anemia, Hypochromic; Animals; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertrophy; Hyp | 1969 |
Biochemical correlates of cardiac hypertrophy. IV. Observations on the cellular organization of growth during myocardial hypertrophy in the rat.
Topics: Animals; Aorta; Autoradiography; Cardiomegaly; Cell Nucleus; Connective Tissue; Connective Tissue Ce | 1969 |
Mechanical properties of rat cardiac muscle during experimental hypertrophy.
Topics: Animals; Aorta, Thoracic; Cardiomegaly; Constriction; Disease Models, Animal; Elasticity; Heart; Hyd | 1971 |
Biochemical correlates of cardiac hypertrophy. V. Labeling of collagen, myosin, and nuclear DNA during experimental myocardial hypertrophy in the rat.
Topics: Animals; Cardiomegaly; Collagen; Connective Tissue; DNA; Extracellular Space; Female; Hydroxyproline | 1972 |
Clinical studies on a Swedish material of pseudoxanthoma elasticum.
Topics: Adolescent; Adult; Aged; Angina Pectoris; Angioid Streaks; Cardiomegaly; Child; Child, Preschool; El | 1972 |
Physiological responses of rats to intermittent high-altitude stress: effects of age.
Topics: Age Factors; Altitude; Animals; Atmosphere Exposure Chambers; Body Weight; Cardiomegaly; Hemoglobino | 1973 |
Effect of exogenous triiodothyronine on weight and composition of the heart in rats.
Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Male; Myocardium; Organ Size; Rats; Triiodot | 1973 |
Effect of long-term physical stress on collagen growth in the lung, heart, and femur of young and adult rats.
Topics: Adaptation, Physiological; Aging; Animals; Body Weight; Calcium; Cardiomegaly; Cardiomyopathies; Col | 1973 |
[Primary cardiac failure in aged subjects].
Topics: Adenosine Triphosphatases; Adult; Age Factors; Aged; Atrial Fibrillation; Autopsy; Cardiomegaly; Car | 1974 |
Synthesis of collagen, myosin, noncollagenous protein, and DNA during experimental myocardial hypertrophy in the rat.
Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; DNA Replication; Hydroxyproline; Muscle Pro | 1972 |
Protocollagen proline hydroxylase activity in rat heart during experimental cardiac hypertrophy.
Topics: Animals; Aorta, Abdominal; Carbon Isotopes; Cardiomegaly; Collagen; Heart Ventricles; Hydroxyproline | 1972 |
[Structural aspects in the hypertrophy of the heart muscle].
Topics: Cardiomegaly; Collagen; Cytochrome c Group; DNA; DNA-Directed RNA Polymerases; Humans; Hydroxyprolin | 1974 |