hydroxyproline has been researched along with Cardiac Remodeling, Ventricular in 48 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1) concentration, myocyte hypertrophy, left ventricular architecture, and in vitro and in vivo cardiac function." | 7.79 | Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction. ( Azevedo, PS; Chiuso-Minicucci, F; dos Santos, PP; Gonçalves, AF; Minicucci, MF; Okoshi, K; Paiva, SA; Pereira, EJ; Polegato, BF; Rafacho, BP; Silva, RA; Zornoff, LA, 2013) |
| " Thus, we evaluated the effects of atorvastatin on cardiac function, remodeling, fibrosis, and apoptosis after myocardial infarction (MI)." | 7.77 | Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. ( Bi, Q; Bolli, R; Dawn, B; Hunt, G; Peng, Y; Sanganalmath, SK; Sato, H; Shirk, G; Tang, XL; Vincent, RJ, 2011) |
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 7.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| "To investigate whether tranilast reduces cardiac fibrosis in rats with two-kidney, one-clip (2K1C) renovascular hypertension." | 7.71 | Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension. ( Bauer, C; Eschenhagen, T; Godes, M; Hocher, B; Neumayer, HH; Olivier, J; Paul, M; Pinto, YM; Slowinski, T; Weil, J, 2002) |
| "We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)." | 7.71 | Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002) |
| "Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1) concentration, myocyte hypertrophy, left ventricular architecture, and in vitro and in vivo cardiac function." | 3.79 | Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction. ( Azevedo, PS; Chiuso-Minicucci, F; dos Santos, PP; Gonçalves, AF; Minicucci, MF; Okoshi, K; Paiva, SA; Pereira, EJ; Polegato, BF; Rafacho, BP; Silva, RA; Zornoff, LA, 2013) |
| " Thus, we evaluated the effects of atorvastatin on cardiac function, remodeling, fibrosis, and apoptosis after myocardial infarction (MI)." | 3.77 | Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. ( Bi, Q; Bolli, R; Dawn, B; Hunt, G; Peng, Y; Sanganalmath, SK; Sato, H; Shirk, G; Tang, XL; Vincent, RJ, 2011) |
| "The present study was designed to determine whether atorvastatin reduced hypertension-induced cardiac remodeling and whether these effects involved Protein Kinase D (PKD) and Myocyte Enhancer Factor 2D (MEF2D), factors known to be implicated in cardiac hypertrophy and fibrosis." | 3.76 | Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats. ( Geng, J; Kang, W; Wang, W; Zhang, Y; Zhao, Z; Zhiming, GE, 2010) |
| " LVH was characterized by increases in the ratios of heart and left ventricular weights to body weight, increased myocyte cross-sectional areas, myocardial and perivascular fibrosis, and elevated cardiac hydroxyproline." | 3.75 | K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function. ( Gao, S; Long, CL; Wang, H; Wang, RH, 2009) |
| "To determine whether therapy with the angiotensin II type 1 receptor blocker (ARB) candesartan and the comparator angiotensin-converting-enzyme inhibitor (ACEI) enalapril during healing after reperfused ST-elevation myocardial infarction (RSTEMI) limit adverse remodeling of infarct zone (IZ) collagens and left ventricular (LV) diastolic dysfunction, we randomized 24 dogs surviving anterior RSTEMI (90-min coronary occlusion) to placebo, candesartan, and enalapril therapy between day 2 and 42." | 3.74 | Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction. ( Idikio, H; Jugdutt, BI; Uwiera, RR, 2007) |
| "Wistar rats were divided into the following 4 groups: 1) C--control (n=13); 2) AoS--aortic stenosis (n=11); 3) LIS--AoS treated with lisinopril, 20 mg/kg/day (n=11); and 4) LOS--AoS treated with losartan, 40 mg/kg/day (n=9)." | 3.73 | [Blockade of renin-angiotensin system attenuates cardiac remodeling in rats undergoing aortic stenosis]. ( Aragon, FF; Cicogna, AC; Cordaro, FR; Gonçalves, G; Okoshi, K; Okoshi, MP; Padovani, CR; Ribeiro, HB; Zornoff, LA, 2005) |
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 3.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| "The combination of ACE inhibitor and ARB, independently of the hypotensive effect, improved LV phenotypic change and increased LV endothelin-1 production and collagen accumulation, diastolic dysfunction, and survival in a rat heart failure model more effectively than either agent alone, thereby providing solid experimental evidence that the combination of these 2 agents is more beneficial than monotherapy for treatment of heart failure." | 3.71 | Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure. ( Iwao, H; Izumi, Y; Kawano, H; Kim, S; Kimoto, M; Yoshiyama, M; Zhan, Y, 2001) |
| "To investigate whether tranilast reduces cardiac fibrosis in rats with two-kidney, one-clip (2K1C) renovascular hypertension." | 3.71 | Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension. ( Bauer, C; Eschenhagen, T; Godes, M; Hocher, B; Neumayer, HH; Olivier, J; Paul, M; Pinto, YM; Slowinski, T; Weil, J, 2002) |
| "We sought to determine whether reperfusion and the calcium channel blocker amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six weeks after myocardial infarction (MI), limit structural vascular remodeling in the noninfarct zone (NIZ)." | 3.71 | Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. ( Idikio, H; Jugdutt, BI; Kumar, D; Menon, V, 2002) |
| " This study aimed to analyze the effects of lisinopril on mortality rate, cardiac function, degree of cardiac hypertrophy and fibrosis in rats with different infarct sizes." | 3.70 | Effects of lisinopril on experimental ischemia in rats. Influence of infarct size. ( Matsubara, BB; Matsubara, LS; Paiva, SA; Spadaro, J; Tornero, MT; Zornoff, LA, 1999) |
| "We sought to compare the effects of two different beta-blockers, carvedilol and metoprolol, to an angiotensin-converting enzyme (ACE) inhibitor (captopril) on myocardial collagen deposition during healing and ventricular remodeling after myocardial infarction (MI)." | 3.70 | Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. ( Chow, LT; Sanderson, JE; Wei, S, 2000) |
| " The use of losartan myocardial infarction causes an attenuation of ventricular remodeling, bringing about an increased survival, an attenuation of ventricular hypertrophy and dilation, and an improvement of the isovolumetric pressure; 2." | 3.70 | Effects of losartan on ventricular remodeling in experimental infarction in rats. ( Matsubara, BB; Matsubara, LS; Paiva, SA; Spadaro, J; Zornoff, LA, 2000) |
| "A rat model of ventricular remodeling after myocardial infarction was established by left coronary artery ligation." | 1.42 | Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats. ( Chen, C; Gao, J; Gao, Y; Guo, J; Wang, H; Wu, R, 2015) |
| "Triptolide (TPL) is a diterpene triepoxide with potent immunosuppressive and anti-inflammatory properties." | 1.42 | Triptolide alleviates isoprenaline-induced cardiac remodeling in rats via TGF-β1/Smad3 and p38 MAPK signaling pathway. ( Chen, J; Huang, D; Huang, Y; Ke, J; Li, L; Liu, M; Wu, W, 2015) |
| "A model of pressure overloaded ventricular remodeling was produced by abdominal aortic constriction (AAC) in rats." | 1.42 | The effect of angoroside C on pressure overload-induced ventricular remodeling in rats. ( Chen, CX; Gao, JP; Gu, WL; Huang, XY, 2015) |
| "Endothelial dysfunction can lead to congestive heart failure and the activation of endothelial ATP-sensitive potassium (K(ATP)) channels may contribute to endothelial protection." | 1.40 | Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy. ( Cui, WY; Long, CL; Wang, H; Zhang, YF; Zhong, ML; Zhou, HM, 2014) |
| "The characteristics of ventricular remodeling in model group included that the heart weight index, myocyte cross-sectional area, myocardial fibrosis, and the hydroxyproline content in cardiac tissue were all increased significantly." | 1.39 | [Effects of ATP-sensitive potassium channel opener iptakalim against ventricular remodeling and its mechanisms of endothelial protection]. ( Cui, WY; Duan, L; Long, CL; Wang, H; Zhang, YF; Zhong, ML; Zhou, HM, 2013) |
| "EERS attenuates ventricular remodeling." | 1.38 | Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats. ( Chen, CX; Huang, XY; Li, YM; Liu, Y; Wu, XM; Zhang, XM, 2012) |
| "The hydroxyproline contents were investigated by spectrophotometric measurement." | 1.37 | [Protective effects of Leonurus japonicas on myocardial remodeling induced by isoproterenol in rats]. ( Gu, YP; Guo, W; Liu, Y; Lv, R; Wei, HC; Yuan, BP; Zhang, C, 2011) |
| "The experimental ventricular remodeling was induced with ligating the left anterior descending branch of the coronary artery of the rats." | 1.36 | Effects of Chinese herb medicine Radix Scrophulariae on ventricular remodeling. ( Chen, CX; Gu, WL; Liu, Y; Lü, J; Wu, Q; Zhang, SJ, 2010) |
| "Ramipril treatment caused an increase in catalase, glutathione peroxidase, and SOD activity in the LV tissue." | 1.35 | A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. ( Chao, CL; Chen, CY; Chen, MF; Ho, YL; Hsu, HC; Lee, BC; Lin, HJ; Lin, YH, 2008) |
| "Chronic heart failure is a multifactorial, progressive disease of many causes and is associated with complex ventricular remodeling." | 1.32 | The structural examination of myocardial samples from patients with end-stage heart failure supported by ventricular assist devices using electron microscopy and amino acid analysis reveals low degree of reverse remodeling. ( Arusoglu, L; Becker, G; Böthig, D; El Banayosy, A; Heimann, P; Jacob, M; Kassner, A; Körfer, R; Mannherz, HG; Meyer, HE; Milting, H; Morshuis, M, 2004) |
| "Left ventricular remodeling and function were followed for 12 weeks post-MI." | 1.32 | Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice. ( Cavasin, MA; Menon, S; Tao, Z; Yang, XP, 2004) |
| "The transition from compensated left ventricular hypertrophy (LVH) to heart failure is associated with alterations in the myocardial interstitium." | 1.31 | Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction. ( Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ, 2001) |
| "Captopril treatment further enhanced pulse pressure by decreasing diastolic blood pressure." | 1.31 | Captopril fails to reverse hypertrophy of the left ventricle induced by aortic insufficiency in rabbits. ( Kyselovic, J; Pelouch, V; Simko, F, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.08) | 18.2507 |
| 2000's | 27 (56.25) | 29.6817 |
| 2010's | 19 (39.58) | 24.3611 |
| 2020's | 1 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| De Beer, D | 1 |
| Mels, CM | 1 |
| Schutte, AE | 1 |
| Louw, R | 1 |
| Delles, C | 1 |
| Kruger, R | 1 |
| Chen, P | 1 |
| Qiao, D | 1 |
| Liu, X | 1 |
| Zhong, ML | 2 |
| Wang, H | 5 |
| Zhou, HM | 2 |
| Zhang, YF | 2 |
| Cui, WY | 2 |
| Long, CL | 3 |
| Duan, L | 1 |
| Minicucci, MF | 2 |
| dos Santos, PP | 1 |
| Rafacho, BP | 2 |
| Gonçalves, AF | 2 |
| Silva, RA | 1 |
| Chiuso-Minicucci, F | 1 |
| Azevedo, PS | 2 |
| Polegato, BF | 2 |
| Okoshi, K | 4 |
| Pereira, EJ | 2 |
| Paiva, SA | 4 |
| Zornoff, LA | 5 |
| Rosa, CM | 1 |
| Xavier, NP | 1 |
| Henrique Campos, D | 1 |
| Fernandes, AA | 1 |
| Cezar, MD | 1 |
| Martinez, PF | 1 |
| Cicogna, AC | 2 |
| Gimenes, C | 1 |
| Gimenes, R | 1 |
| Okoshi, MP | 2 |
| Santos, PP | 1 |
| Ardisson, LP | 1 |
| Batista, DF | 1 |
| Lu, Y | 1 |
| Liu, JJ | 1 |
| Bi, XY | 1 |
| Yu, XJ | 1 |
| Kong, SS | 1 |
| Qin, FF | 1 |
| Zhou, J | 1 |
| Zang, WJ | 1 |
| Gao, Y | 1 |
| Gao, J | 1 |
| Chen, C | 1 |
| Guo, J | 1 |
| Wu, R | 1 |
| Liu, M | 1 |
| Chen, J | 1 |
| Huang, Y | 1 |
| Ke, J | 1 |
| Li, L | 1 |
| Huang, D | 1 |
| Wu, W | 1 |
| Huang, J | 2 |
| Tang, X | 1 |
| Liang, X | 1 |
| Wen, Q | 1 |
| Zhang, S | 1 |
| Xuan, F | 1 |
| Jian, J | 1 |
| Lin, X | 1 |
| Huang, R | 1 |
| Gu, WL | 2 |
| Chen, CX | 3 |
| Huang, XY | 2 |
| Gao, JP | 1 |
| Chen, CY | 1 |
| Lee, BC | 1 |
| Hsu, HC | 1 |
| Lin, HJ | 1 |
| Chao, CL | 1 |
| Lin, YH | 1 |
| Ho, YL | 1 |
| Chen, MF | 1 |
| Gao, S | 2 |
| Wang, RH | 1 |
| Geng, J | 1 |
| Zhao, Z | 1 |
| Kang, W | 1 |
| Wang, W | 1 |
| Zhang, Y | 2 |
| Zhiming, GE | 1 |
| French, CJ | 1 |
| Zaman, AK | 1 |
| Sobel, BE | 1 |
| Baraka, A | 1 |
| Mikhail, M | 1 |
| Guemei, A | 1 |
| El Ghotny, S | 1 |
| Adamcová, M | 1 |
| Potáčová, A | 1 |
| Popelová, O | 1 |
| Štěrba, M | 1 |
| Mazurová, Y | 1 |
| Aupperle, H | 1 |
| Geršl, V | 1 |
| Zuo, YM | 1 |
| Cao, JF | 1 |
| Liu, XY | 1 |
| Yu, HJ | 1 |
| Wu, Q | 1 |
| Lü, J | 1 |
| Liu, Y | 3 |
| Zhang, SJ | 1 |
| Tang, XL | 1 |
| Sanganalmath, SK | 1 |
| Sato, H | 1 |
| Bi, Q | 1 |
| Hunt, G | 1 |
| Vincent, RJ | 1 |
| Peng, Y | 1 |
| Shirk, G | 1 |
| Dawn, B | 1 |
| Bolli, R | 1 |
| Zhang, XM | 1 |
| Wu, XM | 1 |
| Li, YM | 1 |
| Zhang, C | 1 |
| Gu, YP | 1 |
| Yuan, BP | 1 |
| Guo, W | 1 |
| Wei, HC | 1 |
| Lv, R | 1 |
| Yuan, QY | 1 |
| Chu, BC | 1 |
| Li, XJ | 1 |
| Li, XS | 1 |
| Si, LY | 1 |
| Joseph, J | 1 |
| Washington, A | 1 |
| Joseph, L | 1 |
| Koehler, L | 1 |
| Fink, LM | 1 |
| Hauer-Jensen, M | 1 |
| Kennedy, RH | 1 |
| McGowan, BS | 1 |
| Scott, CB | 1 |
| Mu, A | 1 |
| McCormick, RJ | 1 |
| Thomas, DP | 1 |
| Margulies, KB | 1 |
| Milting, H | 1 |
| Jacob, M | 1 |
| Kassner, A | 1 |
| Heimann, P | 1 |
| Mannherz, HG | 1 |
| Becker, G | 1 |
| Meyer, HE | 1 |
| Böthig, D | 1 |
| Arusoglu, L | 1 |
| Morshuis, M | 1 |
| Körfer, R | 1 |
| El Banayosy, A | 1 |
| Cavasin, MA | 1 |
| Tao, Z | 1 |
| Menon, S | 1 |
| Yang, XP | 1 |
| Camp, TM | 1 |
| Tyagi, SC | 2 |
| Aru, GM | 1 |
| Hayden, MR | 1 |
| Mehta, JL | 1 |
| Gonçalves, G | 1 |
| Ribeiro, HB | 1 |
| Cordaro, FR | 1 |
| Padovani, CR | 1 |
| Aragon, FF | 1 |
| Yndestad, A | 1 |
| Vinge, LE | 1 |
| Bjørnerheim, R | 1 |
| Ueland, T | 1 |
| Wang, JE | 1 |
| Frøland, SS | 1 |
| Attramadal, H | 1 |
| Aukrust, P | 1 |
| Oie, E | 1 |
| Du, XJ | 1 |
| Gao, XM | 1 |
| Kiriazis, H | 1 |
| Moore, XL | 1 |
| Ming, Z | 1 |
| Su, Y | 1 |
| Finch, AM | 1 |
| Hannan, RA | 1 |
| Dart, AM | 1 |
| Graham, RM | 1 |
| Agnoletti, G | 1 |
| Cargnoni, A | 1 |
| Agnoletti, L | 1 |
| Di Marcello, M | 1 |
| Balzarini, P | 1 |
| Pasini, E | 1 |
| Gitti, G | 1 |
| Martina, P | 1 |
| Ardesi, R | 1 |
| Ferrari, R | 1 |
| Osadchii, O | 1 |
| Norton, G | 1 |
| Deftereos, D | 1 |
| Woodiwiss, A | 1 |
| Kang, L | 1 |
| Hu, SJ | 1 |
| Jugdutt, BI | 4 |
| Idikio, H | 4 |
| Uwiera, RR | 2 |
| Rocha, FL | 1 |
| Carmo, EC | 1 |
| Roque, FR | 1 |
| Hashimoto, NY | 1 |
| Rossoni, LV | 1 |
| Frimm, C | 1 |
| Anéas, I | 1 |
| Negrão, CE | 1 |
| Krieger, JE | 1 |
| Oliveira, EM | 1 |
| Matsubara, BB | 2 |
| Matsubara, LS | 2 |
| Tornero, MT | 1 |
| Spadaro, J | 2 |
| Wei, S | 1 |
| Chow, LT | 1 |
| Sanderson, JE | 1 |
| O'Brien, DW | 1 |
| Fu, Y | 1 |
| Parker, HR | 1 |
| Chan, SY | 1 |
| Scott, PG | 1 |
| Kim, S | 1 |
| Yoshiyama, M | 1 |
| Izumi, Y | 1 |
| Kawano, H | 1 |
| Kimoto, M | 1 |
| Zhan, Y | 1 |
| Iwao, H | 1 |
| Woodiwiss, AJ | 1 |
| Tsotetsi, OJ | 1 |
| Sprott, S | 1 |
| Lancaster, EJ | 1 |
| Mela, T | 1 |
| Chung, ES | 1 |
| Meyer, TE | 1 |
| Norton, GR | 1 |
| Podesser, BK | 1 |
| Siwik, DA | 1 |
| Eberli, FR | 1 |
| Sam, F | 1 |
| Ngoy, S | 1 |
| Lambert, J | 1 |
| Ngo, K | 1 |
| Apstein, CS | 1 |
| Colucci, WS | 1 |
| Hocher, B | 1 |
| Godes, M | 1 |
| Olivier, J | 1 |
| Weil, J | 1 |
| Eschenhagen, T | 1 |
| Slowinski, T | 1 |
| Neumayer, HH | 1 |
| Bauer, C | 1 |
| Paul, M | 1 |
| Pinto, YM | 1 |
| Menon, V | 1 |
| Kumar, D | 1 |
| Simko, F | 1 |
| Pelouch, V | 1 |
| Kyselovic, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of an Early Phase Single Bolus r-SAK for Acute Myocardial Infarction: a Multi-center Randomized Clinical Trial (OPTIMA-5)[NCT05023681] | Phase 4 | 200 participants (Actual) | Interventional | 2021-10-29 | Completed | ||
| A Single Bolus r-SAK Prior to Primary PCI for ST-elevation Myocardial Infarction (OPTIMA-5): 1-Year Follow-up[NCT05649696] | Phase 4 | 210 participants (Actual) | Interventional | 2021-10-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
48 other studies available for hydroxyproline and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Left ventricular mass and urinary metabolomics in young black and white adults: The African-PREDICT study.
Topics: Adult; Age Factors; Biomarkers; Black People; Echocardiography; Female; Glycine; Humans; Hydroxyprol | 2020 |
Effects and Mechanism of SO2 Inhalation on Rat Myocardial Collagen Fibers.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weights and Measures; Collagen; Heart; Heart Ventricle | 2018 |
[Effects of ATP-sensitive potassium channel opener iptakalim against ventricular remodeling and its mechanisms of endothelial protection].
Topics: Animals; Endothelin-1; Hemodynamics; Hydroxyproline; Isoproterenol; KATP Channels; Male; Myocardium; | 2013 |
Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction.
Topics: Analysis of Variance; Animals; Blotting, Western; Body Weights and Measures; Collagen; Echocardiogra | 2013 |
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Cardiac Myosins; Diabetes Mellitus, Experimental; Diabetic Cardi | 2013 |
Periostin as a modulator of chronic cardiac remodeling after myocardial infarction.
Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Collagen Type I; Collagen Type III; Diastole; D | 2013 |
Pyridostigmine ameliorates cardiac remodeling induced by myocardial infarction via inhibition of the transforming growth factor-β1/TGF-β1-activated kinase pathway.
Topics: Animals; Cholinesterase Inhibitors; Fibrosis; Hemodynamics; Hydroxyproline; Male; MAP Kinase Kinase | 2014 |
Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy.
Topics: Administration, Oral; Allyl Compounds; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relation | 2014 |
Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats.
Topics: Aldosterone; Animals; Antioxidants; Captopril; Collagen; Coronary Occlusion; Coronary Vessels; Endot | 2015 |
Triptolide alleviates isoprenaline-induced cardiac remodeling in rats via TGF-β1/Smad3 and p38 MAPK signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiotonic Agents; Diterpenes; Ep | 2015 |
The Effects of 17-Methoxyl-7-Hydroxy-Benzene-Furanchalcone on Pressure Overload-Induced Cardiac Remodeling in Rats and the Endothelial Mechanisms Based on PGI2.
Topics: Animals; Aorta, Abdominal; Cardiovascular Agents; Chalcones; Constriction, Pathologic; Endothelium, | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Couma | 2015 |
A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit.
Topics: Animals; Blotting, Western; Catalase; Cyclophilin A; Down-Regulation; Echocardiography; Electrophore | 2008 |
K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function.
Topics: Animals; Aorta, Abdominal; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Agents; Disease | 2009 |
Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats.
Topics: Animals; Atorvastatin; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoi | 2010 |
Cardiac fibrosis and diastolic dysfunction after myocardial infarction in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; Body Weight; Diastole; Disease Models, Animal; Echocardiography, Doppler | 2009 |
Effect of targeting mitogen-activated protein kinase on cardiac remodeling in rats.
Topics: Animals; Blood Pressure; Caspase 3; Drug Delivery Systems; Fluorobenzenes; Heart Ventricles; Hydroxy | 2009 |
Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Chronic Disease; Coll | 2010 |
[Effects of oligomeric grape seed proanthocyanidins on isoproterenol-induced cardiac remodeling in rats].
Topics: Animals; Antioxidants; Grape Seed Extract; Heart Rate; Hydroxyproline; Isoproterenol; Male; Malondia | 2010 |
Effects of Chinese herb medicine Radix Scrophulariae on ventricular remodeling.
Topics: Angiotensin II; Animals; Collagen; Coronary Vessels; Hydroxyproline; Ligation; Male; Myocardial Infa | 2010 |
Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction.
Topics: Animals; Apoptosis; Atorvastatin; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhib | 2011 |
Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Chemical Analysis; Captopril; Cardiomegaly | 2012 |
[Protective effects of Leonurus japonicas on myocardial remodeling induced by isoproterenol in rats].
Topics: Animals; Antioxidants; Collagen; Disease Models, Animal; Hemodynamics; Hydroxyproline; Immunohistoch | 2011 |
A targeted high-efficiency angiogenesis strategy as therapy for myocardial infarction.
Topics: Animals; Coronary Vessels; Dogs; Genetic Therapy; Human Growth Hormone; Humans; Hydroxyproline; Male | 2012 |
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats.
Topics: Animals; Arterioles; Collagen; Coronary Vessels; Diastole; Disease Models, Animal; Food, Formulated; | 2002 |
Unloading-induced remodeling in the normal and hypertrophic left ventricle.
Topics: Algorithms; Amino Acids; Animals; Blotting, Western; Cell Separation; Echocardiography; Gelatin; Hea | 2003 |
The structural examination of myocardial samples from patients with end-stage heart failure supported by ventricular assist devices using electron microscopy and amino acid analysis reveals low degree of reverse remodeling.
Topics: Adolescent; Adult; Aged; Child; Collagen; Heart Failure; Heart Transplantation; Heart Ventricles; He | 2004 |
Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice.
Topics: Acute Disease; Animals; Blood Pressure; Body Weight; Chronic Disease; Collagen; Female; Heart; Heart | 2004 |
Doxycycline ameliorates ischemic and border-zone remodeling and endothelial dysfunction after myocardial infarction in rats.
Topics: Animals; Cardiotonic Agents; Doxycycline; Endocardium; Hydroxyproline; Matrix Metalloproteinase 2; M | 2004 |
[Blockade of renin-angiotensin system attenuates cardiac remodeling in rats undergoing aortic stenosis].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic V | 2005 |
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats.
Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hydroxyprolin | 2006 |
Transgenic alpha1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival.
Topics: Actins; Aging; Animals; Atrial Natriuretic Factor; Collagen; Echocardiography; Female; Fibronectins; | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Experimental ischemic cardiomyopathy: insights into remodeling, physiological adaptation, and humoral response.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Echocardiography, Doppler; Heart R | 2006 |
Rat strain-related differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function.
Topics: Adrenergic Agonists; Animals; Blood Pressure; Cell Size; Diastole; Dose-Response Relationship, Drug; | 2007 |
[Effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats].
Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Blood Pressure; Heptanoic Acids; Hydroxy | 2007 |
Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting En | 2007 |
Therapeutic drugs during healing after myocardial infarction modify infarct collagens and ventricular distensibility at elevated pressures.
Topics: Animals; Blood Pressure; Collagen; Dogs; Drug-Related Side Effects and Adverse Reactions; Hydroxypro | 2007 |
Anabolic steroids induce cardiac renin-angiotensin system and impair the beneficial effects of aerobic training in rats.
Topics: Anabolic Agents; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; C | 2007 |
Effects of lisinopril on experimental ischemia in rats. Influence of infarct size.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Fibrosis; Hydroxyproline; Lisinopri | 1999 |
Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Carvedil | 2000 |
Differential morphometric and ultrastructural remodelling in the left atrium and left ventricle in rapid ventricular pacing-induced heart failure.
Topics: Animals; Cardiac Pacing, Artificial; Collagen; Dogs; Heart Atria; Heart Failure; Heart Ventricles; H | 2000 |
Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2001 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collage | 2001 |
Effects of losartan on ventricular remodeling in experimental infarction in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Hydroxyproline; Losartan; Ma | 2000 |
ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium-Transporting ATPases; Endothelin Recepto | 2001 |
Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Division; Fibrosis; Heart Ve | 2002 |
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers; | 2002 |
Captopril fails to reverse hypertrophy of the left ventricle induced by aortic insufficiency in rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aortic Valve Insufficien | 2002 |