hydroxyproline has been researched along with Cancer of Lung in 42 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Breast cancer patients (n = 224) aged 28 to 81 were postoperatively followed up with serial determinations of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and urinary hydroxyproline (OHP)." | 7.67 | A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients. ( Carpi, A; Di Marco, G; Giordani, R; Giuliani, L; Nicolini, A; Palla, S, 1989) |
| " Pulmonary fibrosis was evaluated by measuring alveolar septal wall thickness and the hydroxyproline content of lungs by immunohistochemical staining of lung sections for collagen III and by Masson's trichrome staining of lung sections." | 3.71 | Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice. ( Geng, L; Hallahan, DE; Shyr, Y, 2002) |
| "Breast cancer patients (n = 224) aged 28 to 81 were postoperatively followed up with serial determinations of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and urinary hydroxyproline (OHP)." | 3.67 | A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients. ( Carpi, A; Di Marco, G; Giordani, R; Giuliani, L; Nicolini, A; Palla, S, 1989) |
| " Seven of these parameters were raised in more than half of the 17 patients of the series with overt metastases; these were serum ferritin (88%), C-reactive protein (87%), carcinoembryonic antigen (81%), acid glycoprotein (75%), total alkaline phosphatase (64%), sialyl transferase (56%), andthe urinary hydroxyproline/creatinine ratio (73%)." | 3.65 | Biochemical markers in human breast cancer. ( Coombes, RC; Ford, HT; Gazet, JC; Laurence, DJ; Neville, AM; Powles, TJ; Sloane, JP, 1977) |
| "In this malignancy, the HCG level suggests the diagnosis and stage, confirms response to therapy, and predicts relapse." | 2.37 | Tumor markers: value and limitations in the management of cancer patients. ( Bates, SE; Longo, DL, 1985) |
| "Two of the patients had primary prostate cancer and one had a squamous cell lung tumour." | 1.43 | Inhibition of cancer cell mitosis by reducing the availability of phosphate. ( Condon, JR, 2016) |
| "Amentoflavone treatment significantly reduced tumor nodule formation accompanied by reduced lung collagen hydroxyproline, hexosamine, and uronic acid levels." | 1.34 | Effect of amentoflavone on the inhibition of pulmonary metastasis induced by B16F-10 melanoma cells in C57BL/6 mice. ( Guruvayoorappan, C; Kuttan, G, 2007) |
| "The Caffeine treated metastatic tumour bearing animals significantly (p<0." | 1.31 | Effect of Caffeine, a xanthine derivative, in the inhibition of experimental lung metastasis induced by B16F10 melanoma cells. ( Gude, RP; Menon, LG; Rao, SG, 2001) |
| "Genistein treatment also increased the life span of the tumor-bearing animals (47." | 1.30 | Effect of isoflavones genistein and daidzein in the inhibition of lung metastasis in mice induced by B16F-10 melanoma cells. ( Chang, YC; Kuttan, G; Kuttan, R; Menon, LG; Nair, MG, 1998) |
| "Curcumin and catechin treatment (10 microg/ml) significantly inhibited the invasion of B16F-10 melanoma cells across the collagen matrix of the Boyden chamber." | 1.30 | Anti-metastatic activity of curcumin and catechin. ( Kuttan, G; Kuttan, R; Menon, LG, 1999) |
| "The effects of three different dosage schedules on both therapeutic effect and pulmonary toxicity of bleomycin were studied in mice." | 1.26 | Improved therapeutic index of bleomycin when administered by continuous infusion in mice. ( Collins, JM; Gram, TE; Mimnaugh, EG; Sikic, BI, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (50.00) | 18.7374 |
| 1990's | 8 (19.05) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 4 (9.52) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, EJ | 1 |
| Kwon, S | 1 |
| Reedy, JL | 1 |
| White, AO | 1 |
| Song, JS | 1 |
| Hwang, I | 1 |
| Chung, JY | 1 |
| Ylaya, K | 1 |
| Hewitt, SM | 1 |
| Citrin, DE | 1 |
| Prabhu, VV | 1 |
| Guruvayoorappan, C | 2 |
| Condon, JR | 1 |
| Lee, SJ | 1 |
| Chung, IM | 1 |
| Kim, MY | 1 |
| Park, KD | 1 |
| Park, WH | 1 |
| Park, WW | 1 |
| Moon, HI | 1 |
| Pratheeshkumar, P | 2 |
| Kuttan, G | 10 |
| Raphael, TJ | 1 |
| Thejass, P | 1 |
| Sunila, ES | 1 |
| Dubravsky, NB | 1 |
| Dubrawsky, C | 1 |
| Jampolis, S | 1 |
| Mason, K | 1 |
| Hunter, N | 1 |
| Withers, HR | 1 |
| Kelleher, PC | 1 |
| Smith, CJ | 1 |
| Emura, M | 1 |
| Richter-Reichhelm, HB | 1 |
| Böning, W | 1 |
| Eichinger, R | 1 |
| Schoch, C | 1 |
| Althoff, J | 1 |
| Mohr, U | 1 |
| Svojtková, E | 2 |
| Deyl, Z | 2 |
| Andrlíková, J | 1 |
| Macek, K | 1 |
| Adam, M | 1 |
| Dreicer, R | 1 |
| Kemp, JD | 1 |
| Stegink, LD | 1 |
| Cardillo, T | 1 |
| Davis, CS | 1 |
| Forest, PK | 1 |
| See, WA | 1 |
| Antony, S | 2 |
| Kuttan, R | 4 |
| Karna, E | 2 |
| Pałka, J | 1 |
| Chyczewski, L | 1 |
| Słodkowska, J | 1 |
| Bogdan, J | 1 |
| Menon, LG | 3 |
| Nair, MG | 1 |
| Chang, YC | 1 |
| Kołaczkowska, M | 1 |
| Junik, R | 1 |
| Rzymkowska, M | 1 |
| Kramer, L | 1 |
| Gude, RP | 1 |
| Rao, SG | 1 |
| Hallahan, DE | 1 |
| Geng, L | 1 |
| Shyr, Y | 1 |
| Pałka, JA | 1 |
| Coombes, RC | 1 |
| Powles, TJ | 1 |
| Gazet, JC | 1 |
| Ford, HT | 1 |
| Sloane, JP | 1 |
| Laurence, DJ | 1 |
| Neville, AM | 1 |
| Sikic, BI | 1 |
| Collins, JM | 1 |
| Mimnaugh, EG | 1 |
| Gram, TE | 1 |
| Nixon, JE | 1 |
| Wales, JH | 1 |
| Scanlan, RA | 1 |
| Bills, DD | 1 |
| Sinnhuber, RO | 1 |
| Heppleston, AG | 1 |
| Pawelec, D | 3 |
| Mykała-Cieśla, J | 1 |
| Gmiśki, J | 1 |
| Machalski, M | 1 |
| Drózdz, M | 1 |
| Bates, SE | 1 |
| Longo, DL | 1 |
| Teshima, T | 1 |
| Chatani, M | 1 |
| Inoue, T | 1 |
| Hirokawa, Y | 1 |
| Wadasaki, K | 1 |
| Kasiwado, K | 1 |
| Kagemoto, M | 1 |
| Katsuta, S | 1 |
| Honke, Y | 1 |
| Koyama, T | 1 |
| Nicolini, A | 1 |
| Carpi, A | 1 |
| Di Marco, G | 1 |
| Giuliani, L | 1 |
| Giordani, R | 1 |
| Palla, S | 1 |
| Body, JJ | 1 |
| Borkowski, A | 1 |
| Cleeren, A | 1 |
| Bijvoet, OL | 1 |
| Stevens, MJ | 1 |
| Brocard, H | 1 |
| Akoun, G | 1 |
| Bruhat, M | 1 |
| Bayard, D | 1 |
| Greenblatt, M | 1 |
| Lijinsky, W | 1 |
| Mirejovská, E | 1 |
| Beska, F | 1 |
| Pitronová, M | 1 |
| Guzzo, CE | 1 |
| Pachas, WN | 1 |
| Pinals, RS | 1 |
| Krant, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydroxyproline and Cancer of Lung
| Article | Year |
|---|---|
Collagen metabolites in the urine and serum of patients with cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Collagen; Colorimetry; Female; Humans; Hydroxylysine; Hydroxyproli | 1982 |
Silica and asbestos: contrasts in tissue response.
Topics: Animals; Asbestos; Asbestosis; Cell Survival; Chick Embryo; Fibroblasts; Guinea Pigs; Humans; Hydrox | 1979 |
Tumor markers: value and limitations in the management of cancer patients.
Topics: Acid Phosphatase; Adrenocorticotropic Hormone; Alkaline Phosphatase; alpha-Fetoproteins; Breast Neop | 1985 |
3 trials available for hydroxyproline and Cancer of Lung
| Article | Year |
|---|---|
A phase II trial of deferoxamine in patients with hormone-refractory metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Creatinine; Deferoxami | 1997 |
[The effect of chemotherapy on bone metabolism in patients with non-small cell lung cancer].
Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; B | 1998 |
[A multiinstitutional prospective randomized study of radiation therapy of bone metastasis. II. Prognostic factors].
Topics: Bone Neoplasms; Creatinine; Humans; Hydroxyproline; Lung Neoplasms; Multicenter Studies as Topic; Pr | 1989 |
36 other studies available for hydroxyproline and Cancer of Lung
| Article | Year |
|---|---|
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis.
Topics: Alveolar Epithelial Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cell Polarity; Cellular Senescen | 2021 |
Inhibition of metastatic lung cancer in C57BL/6 mice by marine mangrove Rhizophora apiculata.
Topics: Animals; Antineoplastic Agents, Phytogenic; Collagen; gamma-Glutamyltransferase; Hexosamines; Hydrox | 2013 |
Inhibition of cancer cell mitosis by reducing the availability of phosphate.
Topics: Acid Phosphatase; Alkaline Phosphatase; Bone and Bones; Carcinoma, Squamous Cell; Glucagon; Humans; | 2016 |
Inhibition of lung metastasis in mice by oligonol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Collagen; gamma-Glutamyltransferase; Hexosamin | 2009 |
Vernonia cinerea Less. inhibits tumor cell invasion and pulmonary metastasis in C57BL/6 mice.
Topics: Animals; Asteraceae; Cell Movement; Cell Proliferation; Cell Survival; Collagen; Culture Media, Cond | 2011 |
Antimetastatic potential of vernolide-A, a sesquiterpenoid from Vernonia cinerea L.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gen | 2012 |
Effect of naturally occurring monoterpenes carvone, limonene and perillic acid in the inhibition of experimental lung metastasis induced by B16F-10 melanoma cells.
Topics: Animals; Cell Line, Tumor; Collagen; Cyclohexane Monoterpenes; Cyclohexenes; Hexosamines; Hydroxypro | 2003 |
Antimetastatic activity of Sulforaphane.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen | 2006 |
A preliminary study on antimetastatic activity of Thuja occidentalis L. in mice model.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; gamma | 2006 |
Effect of amentoflavone on the inhibition of pulmonary metastasis induced by B16F-10 melanoma cells in C57BL/6 mice.
Topics: Animals; Antineoplastic Agents; Biflavonoids; Cell Proliferation; Hexosamines; Humans; Hydroxyprolin | 2007 |
Long-term effects of pulmonary damage in mice on lung weight, compliance, hydroxyproline content and formation of metastases.
Topics: Animals; Bleomycin; Fibrosarcoma; Hydroxyproline; Lung; Lung Compliance; Lung Neoplasms; Mice; Mice, | 1981 |
A fetal respiratory epithelial cell line for studying some problems of transplacental carcinogenesis in Syrian golden hamsters.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Epithelial Cells; Female; Fetus; Hy | 1982 |
Decrease in pyrrole-2-carboxylic acid excretion during lung cancer disease.
Topics: Collagen; Humans; Hydroxyproline; Lung Neoplasms; Proline | 1982 |
Determination of specific urinary hydroxyproline-containing peptides in patients with lung cancer.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, Gel; Humans; Hydroxyproline; Lung Neoplasms; Pepti | 1980 |
Effect of viscum album in the inhibition of lung metastasis in mice induced by B16F10 melanoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Hydroxyproline; Lung; Lung Neoplasms; | 1997 |
Prolidase and prolinase activities in moderately and poorly differentiated lung adenocarcinoma.
Topics: Adenocarcinoma; Cell Differentiation; Collagen; Dipeptidases; Humans; Hydroxyproline; Lung; Lung Neo | 1997 |
Effect of isoflavones genistein and daidzein in the inhibition of lung metastasis in mice induced by B16F-10 melanoma cells.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Collagen; Genistein; Hydroxyproline; Isoflavones; | 1998 |
Inhibition of lung metastasis by adoptive immunotherapy using Iscador.
Topics: Animals; Antineoplastic Agents, Phytogenic; Collagen; gamma-Glutamyltransferase; Hydroxyproline; Imm | 1999 |
Anti-metastatic activity of curcumin and catechin.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Adhesion; Cell Movement; Collagen; Curcumin; Female; | 1999 |
Effect of Caffeine, a xanthine derivative, in the inhibition of experimental lung metastasis induced by B16F10 melanoma cells.
Topics: Animals; Caffeine; Female; Hydroxyproline; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, | 2001 |
Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice.
Topics: Animals; Collagen Type III; Dose-Response Relationship, Radiation; Hydroxyproline; Intercellular Adh | 2002 |
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Topics: Adenocarcinoma; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents | 2002 |
Biochemical markers in human breast cancer.
Topics: Adenofibroma; Alkaline Phosphatase; Breast Neoplasms; C-Reactive Protein; Carcinoembryonic Antigen; | 1977 |
Improved therapeutic index of bleomycin when administered by continuous infusion in mice.
Topics: Animals; Bleomycin; Dose-Response Relationship, Drug; Hydroxyproline; Lung; Lung Neoplasms; Male; Mi | 1978 |
Null carcinogenic effect of large doses of nitrosoproline and nitrosohydroxyproline in Wistar rats.
Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Synergism; Fatty Acids, Unsaturated; H | 1976 |
[Hydroxyproline and lung diseases].
Topics: Collagen; Connective Tissue; Humans; Hydroxyproline; Lung; Lung Diseases; Lung Neoplasms; Neoplasm M | 1975 |
Evaluation of metabolism of connective tissue proteins in patients with lung cancer.
Topics: Collagen; Connective Tissue; Elastin; Evaluation Studies as Topic; Female; Humans; Hydroxylysine; Hy | 1992 |
A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Follow-U | 1989 |
Treatment of malignancy-associated hypercalcemia with intravenous aminohydroxypropylidene diphosphonate.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Female; Head and | 1986 |
Efficacy of aminohydroxypropylidene diphosphonate in the treatment of malignancy-associated hypercalcaemia.
Topics: Adenosine Diphosphate; Bone Neoplasms; Breast Neoplasms; Calcium; Drug Evaluation; Female; Humans; H | 1987 |
[Urinary excretion of 5-hydroxyproline in lung cancer].
Topics: Female; Humans; Hydroxyproline; Lung Diseases; Lung Neoplasms; Male | 1968 |
[Value of urine hydroxyproline determination in patients with lung neoplasms].
Topics: Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Humans; Hydroxyproline; Lung Neoplasms; Middle Age | 1974 |
Failure to induce tumors in Swiss mice after concurrent administration of amino acids and sodium nitrite.
Topics: Adenoma; Animals; Arginine; Carcinogens; Female; Hydroxyproline; Lung Neoplasms; Male; Mice; Neoplas | 1972 |
[Urinary hydroxyproline in some non-specific lung diseases].
Topics: Adult; Aged; Collagen; Female; Humans; Hydroxyproline; Lung Diseases; Lung Neoplasms; Male; Middle A | 1972 |
The significance of hydroxyprolinuia for the proof of bone metastases of tumours.
Topics: Bone Neoplasms; Breast Neoplasms; Humans; Hydroxyproline; Lung Neoplasms; Neoplasm Metastasis; Radio | 1968 |
Urinary hydroxyproline excretion in patients with cancer.
Topics: Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Collagen; Creatine; Female; Humans; | 1969 |