Page last updated: 2024-11-06

hydroxyproline and Bone Cancer

hydroxyproline has been researched along with Bone Cancer in 178 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" In 21 patients with breast cancer and TIO, we determined the biochemical effects of a single infusion of pamidronate given at 30 mg (n = 5), 60 mg (n = 5), 90 mg (n = 5), or 120 mg (n = 6)."9.08Intravenous pamidronate in patients with tumor-induced osteolysis: a biochemical dose-response study. ( Body, JJ; Dumon, JC; Ford, J; Piccart, M, 1995)
"The superiority of pamidronate in controlling hypercalcemia is mirrored by the changes observed in these markers."9.08Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. ( Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J, 1997)
" Pamidronate disodium, a bisphosphonate, may prove helpful in the palliative treatment of bone metastases in patients with breast cancer as demonstrated in this multicenter, dose-ranging trial."9.07Intravenous pamidronate disodium treatment of bone metastases in patients with breast cancer. A dose-seeking study. ( Browning, S; Fram, RJ; George, S; Glover, D; Keller, A; Lipton, A; Macerata, RS; Miller, AA; Seaman, JJ; Zelenakas, K, 1994)
"The excretion of urinary hydroxyproline has been measured before mastectomy in 342 patients presenting with breast cancer for the first time to Guy's Hospital."7.67Urinary hydroxyproline and prognosis in human breast cancer. ( Grant, CS; Hayward, JL; Hoare, SA; Millis, RR; Wang, DY, 1984)
"The values of urinary hydroxyproline excretion reflecting the bone remodelling by osteoclasts, and the bone isoenzyme of serum alkaline phosphatase reflecting the osteoblastic function, in 100 randomly selected healthy subjects, 100 patients with primary hyperparathyroidism, and 100 patients with osteolytic secondary tumorous deposits in the skeleton showed a bivariate lognormal distribution."7.67Bone alkaline phosphatase isoenzyme and urinary hydroxyproline in healthy subjects, patients with osteolytic metastases, and patients with primary hyperparathyroidism. ( Bek, V; Broulík, P; Mikulecký, M; Pacovský, V; Stĕpán, JJ, 1989)
"Breast cancer patients (n = 224) aged 28 to 81 were postoperatively followed up with serial determinations of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and urinary hydroxyproline (OHP)."7.67A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients. ( Carpi, A; Di Marco, G; Giordani, R; Giuliani, L; Nicolini, A; Palla, S, 1989)
"Serial estimations of the hydroxyproline (OHP) excretion during chemotherapy were performed in 24 women bearing advanced breast carcinoma with skeletal metastases."7.66[Variable behavior of urinary hydroxyproline in breast cancer with osseous metastases]. ( Fazzin, G; Maccari, F; Nascimben, O; Polico, C, 1978)
"The postabsorptive urinary hydroxyproline excretion test (Spot-HYPRO) was evaluated for its usefulness in reflecting the presence or absence of bone metastasis in 75 women with breast cancer."7.66The postabsorptive hydroxyproline in the long-term evaluation of patients with breast cancer. ( McDonald, MW; Neely, CL; Niell, HB; Palmieri, GM, 1983)
"A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0."7.66Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978)
"Postabsorptive urine hydroxyproline (HYPRO) excretion ("spot" HYPRO test) was compared with the 24-hour urine excretion of HYPRO in 45 patients with breast cancer and nine normal subjects on a low-gelatin diet."7.66Postabsorptive urinary hydroxyproline test in patients with metastatic bone disease from breast cancer. ( McDonald, MW; Neely, CL; Niell, HB; Palmieri, GM, 1981)
"Urinary hydroxyproline was elevated significantly in patients with untreated stage D prostatic carcinoma when compared to values in patients with benign prostatic hypertrophy and prostatic carcinoma without bony metastasis."7.66Urinary hydroxyproline excretion as a marker of osseous metastasis in carcinoma of the prostate. ( Kim, H; Mooppan, MM; Tobin, MS; Wang, JC; Wax, SH, 1980)
" We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer."7.65Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976)
"The hydroxyproline/creatinine excretion ratios have been measured in half-hour fasting morning urine specimens from breast cancer patients and compared with corresponding values measured in 24 hour urine collections."7.65Early morning hydroxyproline excretion in patients with breast cancer. ( Bondy, PK; Leese, CL; Powles, TJ; Rosset, G, 1976)
"In 181 consecutive patients with breast cancer, urinary hydroxyproline excretion has been critically evaluated in conjunction with clinical, biochemical, radiological and scintigraphic parameters."7.65Relevance of hydroxyproline excretion to bone metastasis in breast cancer. ( Dequeker, J; Drochmans, A; Gielen, F; Merlevede, M; Wildiers, J, 1976)
"21 patients had bone metastases diagnosed by bone scanning (99mTc MDP)."5.26Urine hydroxyproline excretion--a marker of bone metastases in prostatic carcinoma. ( Bishop, MC; Fellows, GJ, 1977)
"Patient's with carcinoma metastases in bone and Pagent's disease of bone have different patterns of collagen metabolite excretion."5.26Urinary excretion of hydroxyproline, hydroxylysine and hydroxylysine glycosides by patients with Paget's disease of bone and carcinoma with metastases in bone. ( Kelleher, PC, 1979)
"Patients with skeletal metastases (n = 24) showed significantly higher hydroxyproline excretion in the urine than did those with prostate cancer without metastases, or healthy men of the same age (n = 35)."5.26Urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases. ( Bichler, KH; Harzmann, R; Heller, W; Schmidt, K, 1979)
"When surgery fails to cure breast cancer it is due to disseminated micrometastases present at the time of operation."5.26Hydroxyproline excretion in the detection of occult bone metastases from breast cancer. ( Banks, AJ; Morrison, MJ; Roginski, C; Rowse, AD; Scott, PH, 1982)
"15 patients with breast cancer and proven bone metastases have been studied."5.26[Hydroxyproline in the diagnosis of bone metastases in breast cancer]. ( Alberto, P; Courvoisier, B; Depierre, D; Gasser, AB, 1977)
" In 21 patients with breast cancer and TIO, we determined the biochemical effects of a single infusion of pamidronate given at 30 mg (n = 5), 60 mg (n = 5), 90 mg (n = 5), or 120 mg (n = 6)."5.08Intravenous pamidronate in patients with tumor-induced osteolysis: a biochemical dose-response study. ( Body, JJ; Dumon, JC; Ford, J; Piccart, M, 1995)
"The superiority of pamidronate in controlling hypercalcemia is mirrored by the changes observed in these markers."5.08Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. ( Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J, 1997)
" Pamidronate disodium, a bisphosphonate, may prove helpful in the palliative treatment of bone metastases in patients with breast cancer as demonstrated in this multicenter, dose-ranging trial."5.07Intravenous pamidronate disodium treatment of bone metastases in patients with breast cancer. A dose-seeking study. ( Browning, S; Fram, RJ; George, S; Glover, D; Keller, A; Lipton, A; Macerata, RS; Miller, AA; Seaman, JJ; Zelenakas, K, 1994)
" Eight of these patients had either hypercalcemia or hypercalciuria, and all 10 had elevated urinary hydroxyproline levels as evidence of active skeletal disease."5.05Effects of dichloromethylene diphosphonate in women with breast carcinoma metastatic to the skeleton. ( Canfield, RE; Hyman, GA; Siris, ES, 1983)
"Amine-carboxyboranes have been shown to prevent osteoporosis and loss of bone mass in rodents."3.69The anti-osteoporotic activity of amine-carboxyboranes in rodents. ( Chen, SY; Hall, IH; Rajendran, KG; Sood, A; Spielvogel, BF, 1995)
" We compared several new markers of bone turnover in normocalcaemic patients with breast cancer-induced osteolysis before and after a single infusion of the bisphosphonate pamidronate."3.69Comparative evaluation of markers of bone resorption in patients with breast cancer-induced osteolysis before and after bisphosphonate therapy. ( Body, JJ; Delmas, PD; Dumon, JC; Gineyts, E, 1997)
"We evaluated the serum osteocalcin and alkaline phosphatase levels and the urinary hydroxyproline excretion in patients with blastic, lithic or mixed metastases, humoral malignant hypercalcemia (HMH) and myeloma."3.68[Bone turnover markers in tumor pathology with bone involvement]. ( Amado Señarís, JA; González Macías, J; Napal Lecumberri, J; Pesquera, C; Riancho, JA, 1990)
"The excretion of urinary hydroxyproline has been measured before mastectomy in 342 patients presenting with breast cancer for the first time to Guy's Hospital."3.67Urinary hydroxyproline and prognosis in human breast cancer. ( Grant, CS; Hayward, JL; Hoare, SA; Millis, RR; Wang, DY, 1984)
"The values of urinary hydroxyproline excretion reflecting the bone remodelling by osteoclasts, and the bone isoenzyme of serum alkaline phosphatase reflecting the osteoblastic function, in 100 randomly selected healthy subjects, 100 patients with primary hyperparathyroidism, and 100 patients with osteolytic secondary tumorous deposits in the skeleton showed a bivariate lognormal distribution."3.67Bone alkaline phosphatase isoenzyme and urinary hydroxyproline in healthy subjects, patients with osteolytic metastases, and patients with primary hyperparathyroidism. ( Bek, V; Broulík, P; Mikulecký, M; Pacovský, V; Stĕpán, JJ, 1989)
"Breast cancer patients (n = 224) aged 28 to 81 were postoperatively followed up with serial determinations of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and urinary hydroxyproline (OHP)."3.67A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients. ( Carpi, A; Di Marco, G; Giordani, R; Giuliani, L; Nicolini, A; Palla, S, 1989)
"Thirty-three patients with multiple myeloma were studied with serial skeletal surveys, serum immunoglobulin levels, and postabsorptive urinary hydroxyproline (Spot-HYPRO) determinations."3.67Skeletal surveys in multiple myeloma. Radiologic-clinical correlation. ( Niell, HB; Palmieri, GM; Reidy, TJ; Sebes, JI, 1986)
"The postabsorptive urinary hydroxyproline excretion test (Spot-HYPRO) was evaluated for its usefulness in reflecting the presence or absence of bone metastasis in 75 women with breast cancer."3.66The postabsorptive hydroxyproline in the long-term evaluation of patients with breast cancer. ( McDonald, MW; Neely, CL; Niell, HB; Palmieri, GM, 1983)
"Postabsorptive urine hydroxyproline (HYPRO) excretion ("spot" HYPRO test) was compared with the 24-hour urine excretion of HYPRO in 45 patients with breast cancer and nine normal subjects on a low-gelatin diet."3.66Postabsorptive urinary hydroxyproline test in patients with metastatic bone disease from breast cancer. ( McDonald, MW; Neely, CL; Niell, HB; Palmieri, GM, 1981)
"The authors study the daily elimination of hydroxyproline in breast cancer with and without roentgenological or radioisotopic bone scanning evidence of bone lesion."3.66[Hydroxyprolinuria in relation to bone metastases in patients with breast cancer]. ( Espinós Pérez, D; Millán Núñez-Cortés, J; Rico Lenza, H; Rodríguez Mora, VI, 1980)
"Seventy-one patients with breast cancer and bone metastases, together with other assessable sites of disease, were monitored by radiologic skeletal survey, bone scanning, pain charts, bone marrow aspirate, serum calcium, alkaline phosphatase and urine hydroxyproline/creatinine ratio."3.66Assessment of response of bone metastases to systemic treatment in patients with breast cancer. ( Coombes, RC; Dady, P; Ford, HT; Gazet, JC; McCready, VR; Parsons, C; Powles, TJ, 1983)
"Urinary hydroxyproline was elevated significantly in patients with untreated stage D prostatic carcinoma when compared to values in patients with benign prostatic hypertrophy and prostatic carcinoma without bony metastasis."3.66Urinary hydroxyproline excretion as a marker of osseous metastasis in carcinoma of the prostate. ( Kim, H; Mooppan, MM; Tobin, MS; Wang, JC; Wax, SH, 1980)
"A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0."3.66Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978)
"The urinary excretion of Hydroxyproline (OH-P), evaluated as OH-P/creatinine ratio, has been examined in the follow up of 142 breast cancer patients."3.66[Hydroxyprolinuria and bone metastases of breast cancer]. ( Bardella, D; Cruciani, G; Fiorentini, GM; Marangolo, M; Tavolazzi, L, 1980)
"The Authors have studied total urinary hydroxyproline (TUH), together with other hematochemical analyses, in 104 patients suffering from advanced breast cancer with or without bone metastases."3.66[Urinary hydroxyproline in advanced breast carcinoma and response to treatment with medroxyprogesterone acetate (MAP) in high doses]. ( Biagi, R; Colalongo, G; Jafelice, G; Mambelli, M; Martoni, A; Pannuti, F; Pedelini, G; Piana, E; Rocchetta, G, 1980)
"Serial estimations of the hydroxyproline (OHP) excretion during chemotherapy were performed in 24 women bearing advanced breast carcinoma with skeletal metastases."3.66[Variable behavior of urinary hydroxyproline in breast cancer with osseous metastases]. ( Fazzin, G; Maccari, F; Nascimben, O; Polico, C, 1978)
" We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer."3.65Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976)
"The hydroxyproline/creatinine excretion ratios have been measured in half-hour fasting morning urine specimens from breast cancer patients and compared with corresponding values measured in 24 hour urine collections."3.65Early morning hydroxyproline excretion in patients with breast cancer. ( Bondy, PK; Leese, CL; Powles, TJ; Rosset, G, 1976)
"In 181 consecutive patients with breast cancer, urinary hydroxyproline excretion has been critically evaluated in conjunction with clinical, biochemical, radiological and scintigraphic parameters."3.65Relevance of hydroxyproline excretion to bone metastasis in breast cancer. ( Dequeker, J; Drochmans, A; Gielen, F; Merlevede, M; Wildiers, J, 1976)
"A rapid and significant suppression of bone resorption was observed in all patients after intravenous treatment."2.69Effects of the bisphosphonate olpadronate in patients with carcinoma of the prostate metastatic to the skeleton. ( Hamdy, NA; Lycklama à Nijeholt, AA; Papapoulos, SE; Pelger, RC; Zwinderman, AH, 1998)
"Biochemical markers of bone resorption and bone formation are abnormally raised in the blood and urine of patients with metastatic bone disease."2.41Biochemical markers and skeletal metastases. ( Costa, L; Demers, LM; Lipton, A, 2000)
"Markers of bone resorption are sensitive to changes in bone turnover induced by treatment."2.41Markers of bone turnover in bone metastases. ( Delmas, PD; Fontana, A, 2000)
"Alendronate failed to inhibit MMP-2 activity directly, but instead appeared to block cellular secretion of MMP-2."1.30Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells. ( Stearns, ME, 1998)
"Hydroxyproline was also measured."1.29Biochemical markers for detecting bone metastases in patients with breast cancer. ( Crivellari, D; de Bernard, B; Galligioni, E; Gazzarrini, C; Moro, L; Talamini, R, 1993)
"The present open study included 16 prostate cancer patients who had painful bone metastases and who had failed hormonal therapy."1.29The effect of combined intravenous and oral clodronate treatment on bone pain in patients with metastatic prostate cancer. ( Kylmälä, T; Lindholm, TS; Seppänen, J; Tammela, TL, 1994)
" We propose as a working hypothesis a classification of responses taking into account the criteria: the urinary hydroxyproline to urinary creatinine ratio, the serum dosage of bone isoenzyme of alkaline phosphatase and propeptide of type III procollagen (P III NP), and as an essential element, an analysis of all available imaging techniques."1.28[Response of bone metastases to medical treatment: definition of evaluation criteria and classification trials]. ( Belpomme, D; Bock, P; Cappelaere, P; Droz, JP; Marie, FN; Namer, M; Pecking, A; Rouesse, J; Tan, TN; Vanel, D, 1989)
"Biochemical evaluation showed that bone resorption from metastatic disease was generally not enough to account for hypercalcaemia."1.27Relative contribution of humoral and metastatic factors to the pathogenesis of hypercalcaemia in malignancy. ( Boyle, IT; Fogelman, I; Gardiner, MD; Ralston, SH, 1984)
"Thirty-two men with stage D2 prostatic cancer were monitored by bone scan, acid and alkaline phosphatase values, and urinary hydroxyproline, beginning from 4 to 36 months after initiation of hormonal manipulation and/or systemic chemotherapy."1.27Serial spot hydroxyproline/creatinine ratios in metastatic prostatic cancer. ( Hopkins, SC; Ikard, M; Moinuddin, M; Nissenkorn, I; Palmieri, GM; Soloway, MS, 1983)
"Both were elevated in patients with prostatic cancer with active bone metastases compared to the values of prostatic cancer without bone metastasis and benign prostatic hypertrophy."1.27[Use of urinary hydroxyproline excretion as a marker of bone metastases in prostatic cancer (1)]. ( Imai, K; Kitaura, K; Kurokawa, K; Tomaru, Y; Yamanaka, H, 1985)
"Increases without any evidence of metastases are either due to other diseases with connective tissue changes or to occult micrometastases."1.27[The value of the free hydroxyproline and the N-acetyl-beta- glucosaminidase for the observation of the course of malignant tumors]. ( Lange, H; Müller, A; Ruffert, K, 1986)
"In metastatic prostate cancer where blastic osseous metastases predominate, disease progression on bone scan correlated with elevation of both total hydroxyproline excretion (7."1.27Total and nondialyzable hydroxyproline excretion in Stage D2 prostate cancer. ( Hopkins, SC; Moinuddin, M; Niell, HB; Palmieri, GM; Soloway, MS, 1984)
"In patients with prostatic cancer--the ones with bone metastases proved by bone scanning--urinary HOP levels were found to be 69."1.27Urinary hydroxyproline levels in patients with prostatic carcinoma. ( Adalar, N; Erol, D; Güvençli, S; Simşek, F, 1983)
"In patients with osteolytic lesions from multiple myeloma, elevated T and D levels with normal ND HYPRO values were observed, along with elevated D/ND ratios."1.27Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer. ( Hopkins, SC; Maxwell, TA; Neely, CL; Niell, HB; Palmieri, GM; Soloway, MS, 1983)
" It is concluded that PIP activity dosage in serum may provide with urinary hydroxyproline, further information for the study of collagen metabolism in osteoblastic bone diseases during treatment."1.27[Determination of serum proline iminopeptidase activity using a fluorescent substrate in patients with Paget's disease and prostatic bone metastases. Preliminary results]. ( Bouvier, M; Colson, F; Mathieu, M; Tebib, J; Vianey-Liaud, C, 1986)
"Treatment with gallium nitrate for five to seven days caused a median reduction in 24-hour urinary calcium excretion of 66% relative to baseline measurements (P less than ."1.27Gallium nitrate inhibits accelerated bone turnover in patients with bone metastases. ( Alcock, NW; Bockman, RS; Warrell, RP, 1987)
"Patients with skeletal metastases (n = 24) showed significantly higher hydroxyproline excretion in the urine than did those with prostate cancer without metastases, or healthy men of the same age (n = 35)."1.26Urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases. ( Bichler, KH; Harzmann, R; Heller, W; Schmidt, K, 1979)
"Patients with breast cancer may show an increased requirement for thiamin particularly when treated with 5-fluorouracil, and a number of metabolic disturbances in which ascorbic acid may play a central role."1.26Nutrition and breast cancer. ( Dickerson, JW, 1979)
"15 patients with breast cancer and proven bone metastases have been studied."1.26[Hydroxyproline in the diagnosis of bone metastases in breast cancer]. ( Alberto, P; Courvoisier, B; Depierre, D; Gasser, AB, 1977)
"21 patients had bone metastases diagnosed by bone scanning (99mTc MDP)."1.26Urine hydroxyproline excretion--a marker of bone metastases in prostatic carcinoma. ( Bishop, MC; Fellows, GJ, 1977)
"The development of human tumors is accompanied very often by tumor-associated phenomena such as production of tumor-derived substances, production of certian substances in response to the tumor or immunological reactions."1.26Biological markers of human tumors and monitoring of cancer treatment. ( Nissen, E; Tanneberger, S; Ziegenbein, R, 1979)
"In 25 patients with prostatic cancer and 26 patients with benign prostatic hypertrophy, urinary hydroxyproline excretion as estimated by the method described by Cleary and Saunders."1.26Urinary hydroxyproline excretion as a marker of bone metastasis in prostatic cancer. ( Aoyagi, K; Rinsho, K, 1982)
"Those who had marrow metastasis produced elevated levels of hydroxyproline; the highest excretions were observed when marrow fibrosis was associated with metastasis."1.26Urinary hydroxyproline excretion in myelofibrosis. ( Aung, MK; Tobin, MS; Wang, JC, 1980)
"When surgery fails to cure breast cancer it is due to disseminated micrometastases present at the time of operation."1.26Hydroxyproline excretion in the detection of occult bone metastases from breast cancer. ( Banks, AJ; Morrison, MJ; Roginski, C; Rowse, AD; Scott, PH, 1982)
"It is increased in cases of metastatic cancer of bone."1.26An automatic technique for the routine fractionation of the urinary hydroxyproline containing peptides. ( Borel, JP; Garbe, A; Joubert, PM; Randoux, A; Szymanovicz, A, 1980)
"Patient's with carcinoma metastases in bone and Pagent's disease of bone have different patterns of collagen metabolite excretion."1.26Urinary excretion of hydroxyproline, hydroxylysine and hydroxylysine glycosides by patients with Paget's disease of bone and carcinoma with metastases in bone. ( Kelleher, PC, 1979)
"Of 31 patients with prostatic cancer, 21 have skeletal metastases proven by bone scintigraphy and/or radiology."1.26[Urinary and serum hydroxyproline in the diagnosis of bone metastases of prostatic cancer]. ( Courvoisier, B; Depierre, D; Gasser, AB; Jeannet, C, 1981)
"Lytic activity of eosinophilic granuloma and other tumours was studied in vitro on collagen substrate."1.26Collagenolytic activity of eosinophilic granuloma in vitro. ( Barbey, S; Bazin, S; Mouly, H; Nezelof, C; Rousseau-Merck, MF, 1979)

Research

Studies (178)

TimeframeStudies, this research(%)All Research%
pre-1990154 (86.52)18.7374
1990's22 (12.36)18.2507
2000's2 (1.12)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RUBEGNI, M1
RAVENNI, G1
DEL GIOVANE, L1
KLEIN, L1
LAFFERTY, FW1
PEARSON, OH1
CURTISS, PH1
Platt, WD1
Doolittle, LH1
Hartshorn, JW1
LEE, CA2
LLOYD, HM2
AVIOLI, LV1
MCDONALD, JE1
SINGER, RA1
Takahashi, Y1
Matsuo, M1
Inoue, H1
Raab, W5
Schwägerl, W2
Borel, JP3
Caranjot, JM1
Jayle, MF1
Nakagawa, M1
Sugiura, Y1
Oshima, T2
Kajino, G1
Hirako, H1
Waalkes, TP2
Abeloff, MD1
Ettinger, DS1
Woo, KB1
Gehrke, CW1
Mrochek, JE1
Schulze, G1
Rinsho, K3
Unni Mooppan, MM1
Kim, H2
Wang, JC3
Tobin, MS3
Wax, SH2
Siris, ES3
Hyman, GA1
Canfield, RE3
Coombes, RC5
Dearnaley, DP1
Buckman, R1
Jones, JM1
Ormerod, MG1
Sloane, JP2
Powles, TJ7
Gazet, JC4
Ford, HT4
Neville, AM3
Deeble, TJ1
Goldberg, DM1
Ralston, SH1
Fogelman, I1
Gardiner, MD1
Boyle, IT1
Jacobs, TP2
Bilezikian, JP1
Baquiran, DC1
Shane, E1
Dady, PJ1
Smith, IE1
Parsons, CA1
Henk, JM2
Nash, AG2
Skalková, D1
Romics, I2
Lengyel, L1
Nemoto, S1
Niell, HB5
Neely, CL3
Palmieri, GM6
McDonald, MW2
Maxwell, TA1
Hopkins, SC3
Soloway, MS3
Sanz Ortiz, J1
Mayo Suárez, J1
Riancho Moral, JA1
Amado Señarís, JA2
Erol, D1
Adalar, N1
Güvençli, S1
Simşek, F1
Bellido, V1
Carda, P1
Mascías, E1
Moinuddin, M2
Grant, CS1
Hoare, SA1
Millis, RR1
Hayward, JL1
Wang, DY1
Kelleher, PC2
Smith, CJ1
Nissenkorn, I1
Ikard, M1
Dady, P1
Parsons, C1
McCready, VR1
Hirano, H1
Urist, MR1
Tormey, DC1
Gasser, AB4
Depierre, D4
Mermillod, B1
Courvoisier, B7
Adamo, V1
Altavilla, G1
La Torre, F1
Palmara, D1
Tropea, F1
Rowse, AD1
Morrison, MJ1
Scott, PH1
Banks, AJ1
Roginski, C1
Aoyagi, K1
Rico Lenza, H1
Millán Núñez-Cortés, J1
Rodríguez Mora, VI1
Espinós Pérez, D1
Jeannet, C1
Pemp, W1
Feustel, A1
Bower, L2
Manley, G2
Budavári, I1
Kisbenedek, L1
Balogh, F1
Szymanovicz, A1
Joubert, PM1
Garbe, A1
Randoux, A2
Aung, MK1
Mooppan, MM1
Martoni, A1
Pedelini, G1
Colalongo, G1
Biagi, R1
Mambelli, M1
Jafelice, G1
Rocchetta, G1
Piana, E1
Pannuti, F1
Cruciani, G1
Bardella, D1
Fiorentini, GM1
Marangolo, M1
Tavolazzi, L1
Miyamoto, KK1
McSherry, SA1
Robins, SP1
Besterman, JM1
Mohler, JL1
Plosker, GL1
Goa, KL1
Alcover, J1
Fernández-Conde, M1
Filella, X1
de Osaba, MJ1
Carretero, P1
Glover, D1
Lipton, A2
Keller, A1
Miller, AA1
Browning, S1
Fram, RJ1
George, S1
Zelenakas, K1
Macerata, RS1
Seaman, JJ1
Kylmälä, T1
Tammela, TL1
Lindholm, TS1
Seppänen, J1
Rajendran, KG1
Chen, SY1
Sood, A1
Spielvogel, BF1
Hall, IH1
O'Rourke, N1
McCloskey, E1
Houghton, F1
Huss, H1
Kanis, JA4
Mazières, B2
Laroche, M1
Cantagrel, A1
Wada, S1
Katayama, Y1
Yasutomo, Y1
Kugai, N1
Nagata, N1
Taube, T1
Elomaa, I1
Blomqvist, C1
Beneton, MN1
Moro, L1
Gazzarrini, C1
Crivellari, D1
Galligioni, E1
Talamini, R1
de Bernard, B1
Body, JJ3
Dumon, JC2
Piccart, M1
Ford, J1
Vinholes, J1
Guo, CY1
Purohit, OP1
Eastell, R1
Coleman, RE1
Gineyts, E1
Delmas, PD2
Pelger, RC1
Hamdy, NA1
Zwinderman, AH1
Lycklama à Nijeholt, AA1
Papapoulos, SE1
Stearns, ME1
Kołaczkowska, M1
Junik, R1
Rzymkowska, M1
Kramer, L1
Demers, LM1
Costa, L1
Fontana, A1
Tanneberger, S1
Nissen, E1
Ziegenbein, R1
Stĕpán, J2
Pacovský, V2
Horn, V1
Silinková-Málková, E1
Vokrouhlická, O1
Konopásek, B2
Formánková, J1
Hrba, J1
Marek, J1
Harzmann, R2
Bichler, KH2
Dickerson, JW2
Heller, W1
Schmidt, K1
Pust, R1
Rost, A1
Weidner, W1
Rothauge, CF1
Rousseau-Merck, MF1
Barbey, S1
Mouly, H1
Bazin, S1
Nezelof, C1
Mundy, AR1
Bishop, MC1
Fellows, GJ1
Anson, A1
Cuschieri, A5
Jarvie, R1
Taylor, WH1
Cant, E1
Furnival, CM1
Blumgart, LH1
Ambanelli, U1
Ferraccioli, GF1
Bernardi, P1
Servemti, G1
Polico, C1
Nascimben, O1
Maccari, F1
Fazzin, G1
Burkhardt, H5
Wepler, R2
Rommel, K5
Hillyard, CJ1
Thomas, P1
Keyser, JW1
Marcus, D1
Zinberg, N1
Stimson, WH1
Alberto, P1
Balaba, TIa1
Furtseva, LN1
Nefed'eva, NN1
Gielen, F1
Dequeker, J1
Drochmans, A1
Wildiers, J1
Merlevede, M1
Rosset, G1
Leese, CL2
Bondy, PK3
Roberts, JG2
Baum, M3
Burkhardt, F1
Williams, M1
Bligh, AS1
Szymanowicz, A1
Malgras, A1
Cosson, R1
Roques, CF1
Amigues, H1
Fournie, A1
Arlet, J1
Ruffié, R1
Rotstein, S1
Glas, U1
Eriksson, M1
Pfeiffer, P1
Hansen, J1
Söderqvist, J1
Bandmann, U1
Strid, S1
Zysset, E1
Ammann, P1
Jenzer, A1
Gertz, BJ1
Portmann, L1
Rizzoli, R1
Jaquet-Müller, F1
Pryor-Tillotson, S1
Bonjour, JP1
Burckhardt, P1
Clarke, NW1
McClure, J1
George, NJ1
Takenaka, I1
Miyagawa, I1
Kunitomi, K1
Hirakawa, S1
Matsuoka, N1
Kawamura, H1
Napal Lecumberri, J1
Pesquera, C1
Riancho, JA1
González Macías, J1
Kurokawa, K1
Imai, K1
Yamanaka, H1
Tomaru, Y1
Kitaura, K1
Ruffert, K1
Müller, A1
Lange, H1
Teshima, T1
Chatani, M1
Inoue, T1
Hirokawa, Y1
Wadasaki, K1
Kasiwado, K1
Kagemoto, M1
Katsuta, S1
Honke, Y1
Koyama, T1
Nicolini, A1
Carpi, A1
Di Marco, G1
Giuliani, L1
Giordani, R1
Palla, S1
Belpomme, D1
Droz, JP1
Marie, FN1
Namer, M2
Tan, TN1
Pecking, A1
Rouesse, J1
Vanel, D1
Bock, P1
Cappelaere, P1
Stĕpán, JJ1
Mikulecký, M1
Bek, V2
Broulík, P1
Attardo-Parrinello, G1
Merlini, G1
Pavesi, F1
Crema, F1
Fiorentini, ML1
Ascari, E1
Urwin, GH1
Percival, RC2
Yates, AJ2
Watson, ME1
Couch, M1
McDonald, B1
Forrest, AR1
Williams, JL1
Borkowski, A1
Cleeren, A1
Bijvoet, OL1
Godsall, JW1
Burtis, WJ1
Insogna, KL1
Broadus, AE1
Stewart, AF1
Sebes, JI1
Reidy, TJ1
O'Brien, WM1
Lynch, JH1
Kawamura, J1
Tochigi, H1
Yanagawa, M1
Yoshida, O1
Hida, S1
Mori, O1
Suzuki, N1
Saito, K1
Komatsu, Y1
Hatayama, T1
Conte, N1
Di Virgilio, R1
Roiter, I1
Caberlotto, L1
Francini, G1
Bigazzi, S1
Leone, V1
Gennari, C1
Scher, HI1
Curley, T1
Geller, N1
Dershaw, D1
Chan, E1
Nisselbaum, J1
Alcock, N1
Hollander, P1
Yagoda, A1
Frenay, M1
Boublil, JL1
Khater, R1
Viot, M1
François, E1
Milano, G1
Bouvier, M1
Colson, F1
Tebib, J1
Mathieu, M1
Vianey-Liaud, C1
Hausner, P1
Kolár, J1
Vosecký, M1
Nový, F1
Janko, L1
Knorr, A1
Engelmann, U1
Gross, C1
Friedrich, S1
Serdengeçti, S1
Serdengeçti, K1
Derman, U1
Berkarda, B1
Warrell, RP1
Alcock, NW1
Bockman, RS1
Stevens, MJ1
Charhon, SA1
Chapuy, MC1
Delvin, EE1
Meunier, PJ1
Althoff, J1
Quint, P1
Höhling, HJ1
Roessner, A1
Grundmann, E1
Gray, RE1
Galloway, J1
Rogers, K1
Neal, FE1
Morii, H2
Tanae, A1
Ibayashi, H1
Nakao, K1
Maeda, H1
Radom, S3
Zulawski, M3
Golebiowska, D1
Lejeune, E1
Meunier, P1
Ruitton, P1
Orgiazzi, J1
Kontturi, MJ1
Sotaniemi, EA1
Larmi, TK1
Freiberg, RA1
Air, GW1
Glueck, CJ1
Ishikawa, T1
Abrams, NR1
Manner, G1
Kuleba, M1
Parsons, V2
Dalley, V1
Brinkley, D1
Davies, C1
Vernon, A1
Matsushita, Y1
Hasegawa, K1
Sugimura, R1
Otomo, S1
Basu, TK2
Donaldson, D1
Williams, DC2
Raven, RW1
Dahlig, E1
Drozdz, M1
Kucharz, E1
Sumner, DS1
Edwards, MH1
Aho, AJ1
Einola, S1
Paasio, J1
Zender, R3
Niejadlik, DC1
Felgate, RA1
Felgate, R1
Klimmt, G1
Sári, P1
Uhlich, F1
Sienczewska-Burzyńska, J1
Jaruga-Dolińska, E1
Ogane, S1
Gruson, M1
Ryckewaert, A1
Hioco, D1
Lanham, C1
de Sèze, S1
Kocher, P1
Anyanwu, G2
Endres, O2
Dietrich, M1
Czitober, H2
Kriegel, W1
Langness, U1
Jahn, P1
Yamada, Y1
Carbone, PP1
Zipkin, I1
Sokoloff, L1
Frazier, P1
Cook, P1
Mullins, F1
Mirejovská, E1
Beska, F1
Pitronová, M1
Kerkhoff, JF1
Ditzel, J2
Jordal, R2
Riskoer, N1
Riskaer, N1
Guzzo, CE1
Pachas, WN1
Pinals, RS1
Krant, MJ1
Hosley, HF1
Taft, EG1
Olson, KB1
Gates, S1
Beebe, RT1
Bonadonna, G1
Merlino, MJ1
Myers, WP1
Sonenberg, M1
Mühlbach, R2
Hirthe, D1
Lindenhayn, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420]Phase 14 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for hydroxyproline and Bone Cancer

ArticleYear
Collagen metabolites in the urine and serum of patients with cancer.
    Clinics in laboratory medicine, 1982, Volume: 2, Issue:3

    Topics: Bone Neoplasms; Breast Neoplasms; Collagen; Colorimetry; Female; Humans; Hydroxylysine; Hydroxyproli

1982
Biological markers as prognostic and clinical evaluation tools.
    European journal of cancer, 1980, Volume: Suppl 1

    Topics: Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Chorionic Gonadotropin; Creatinine; Fema

1980
Clodronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease.
    Drugs, 1994, Volume: 47, Issue:6

    Topics: Animals; Bone Neoplasms; Bone Resorption; Calcinosis; Clinical Trials as Topic; Clodronic Acid; Dose

1994
Biochemical markers and skeletal metastases.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl

    Topics: Alkaline Phosphatase; Biomarkers; Bone Development; Bone Neoplasms; Bone Resorption; Humans; Hydroxy

2000
Markers of bone turnover in bone metastases.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl

    Topics: Alkaline Phosphatase; Biomarkers; Bone Development; Bone Neoplasms; Bone Resorption; Collagen; Human

2000
[Indications for urinary hydroxyproline determination].
    Deutsche medizinische Wochenschrift (1946), 1976, Sep-17, Volume: 101, Issue:38

    Topics: Arthritis, Rheumatoid; Bone Neoplasms; Hodgkin Disease; Humans; Hydroxyproline; Neoplasm Metastasis;

1976
Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy.
    Recent progress in hormone research, 1986, Volume: 42

    Topics: Adenylyl Cyclases; Alkaline Phosphatase; Animals; Bone Neoplasms; Calcium; Cyclic AMP; Disease Model

1986
[Urinary excretion of hydroxyproline as an index of systemic collagen metabolism].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1972, Oct-16, Volume: 27, Issue:42

    Topics: Adult; Age Factors; Body Surface Area; Bone and Bones; Bone Diseases; Bone Neoplasms; Calcinosis; Ch

1972

Trials

18 trials available for hydroxyproline and Bone Cancer

ArticleYear
Effects of dichloromethylene diphosphonate in women with breast carcinoma metastatic to the skeleton.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Administration, Oral; Adult; Aged; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clini

1983
Free serum hydroxyproline and total urinary hydroxyproline for the detection of skeletal metastasis.
    British journal of cancer, 1982, Volume: 45, Issue:3

    Topics: Adult; Alkaline Phosphatase; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trial

1982
Intravenous pamidronate disodium treatment of bone metastases in patients with breast cancer. A dose-seeking study.
    Cancer, 1994, Dec-01, Volume: 74, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Bone Neoplasms; Bre

1994
Double-blind, placebo-controlled, dose-response trial of oral clodronate in patients with bone metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Neo

1995
Comparative effects of clodronate and calcitonin on bone in metastatic breast cancer: a histomorphometric study.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:12

    Topics: Adult; Aged; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Calcium;

1993
Intravenous pamidronate in patients with tumor-induced osteolysis: a biochemical dose-response study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:8

    Topics: Adult; Aged; Analysis of Variance; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitriol; Ca

1995
Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Neoplasms; Bone Resorption; Calcium; C

1997
Effects of the bisphosphonate olpadronate in patients with carcinoma of the prostate metastatic to the skeleton.
    Bone, 1998, Volume: 22, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Agents; Bone Neo

1998
[The effect of chemotherapy on bone metabolism in patients with non-small cell lung cancer].
    Pneumonologia i alergologia polska, 1998, Volume: 66, Issue:5-6

    Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; B

1998
Intravenous clodronate for the treatment of hypercalcaemia in breast cancer patients with bone metastases--a prospective randomised placebo-controlled multicentre study.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:4-5

    Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; Bone Neoplasms; Breast Neoplasms; Calcium; Clodronic

1992
Comparison of a rapid (2-h) versus a slow (24-h) infusion of alendronate in the treatment of hypercalcemia of malignancy.
    Bone and mineral, 1992, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Neoplasms; Bone Resorption; Calcium; Diphosphonates; Doub

1992
Disodium pamidronate identifies differential osteoclastic bone resorption in metastatic prostate cancer.
    British journal of urology, 1992, Volume: 69, Issue:1

    Topics: Alkaline Phosphatase; Bone Neoplasms; Bone Resorption; Calcium; Creatinine; Diphosphonates; Humans;

1992
[A multiinstitutional prospective randomized study of radiation therapy of bone metastasis. II. Prognostic factors].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1989, Apr-25, Volume: 49, Issue:4

    Topics: Bone Neoplasms; Creatinine; Humans; Hydroxyproline; Lung Neoplasms; Multicenter Studies as Topic; Pr

1989
Effects of a new aminodiphosphonate (aminohydroxybutylidene diphosphonate) in patients with osteolytic lesions from metastases and myelomatosis. Comparison with dichloromethylene diphosphonate.
    Archives of internal medicine, 1987, Volume: 147, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Antineoplastic Combined Chemotherapy Protocols; Bone Ne

1987
Dichloromethylene diphosphonate action in hematologic and other malignancies.
    Bone, 1987, Volume: 8 Suppl 1

    Topics: Administration, Oral; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clinical Tr

1987
Gallium nitrate in prostatic cancer: evaluation of antitumor activity and effects on bone turnover.
    Cancer treatment reports, 1987, Volume: 71, Issue:10

    Topics: Adenocarcinoma; Aged; Bone and Bones; Bone Neoplasms; Bone Resorption; Calcium; Clinical Trials as T

1987
Salmon calcitonin in the treatment of bone metastases.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcitonin; Calcium; Female; Follow-Up Studies; H

1986
Circadian rhythm of total urinary hydroxyproline excretion and 3-H hydroxyproline test.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 39, Issue:1

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Circadian Rhythm; Clinical Trials as Topic; Female; H

1972

Other Studies

152 other studies available for hydroxyproline and Bone Cancer

ArticleYear
[Increase of urinary elimination of hydroxyproline in osteolytic processes].
    Bollettino della Societa italiana di biologia sperimentale, 1962, Sep-30, Volume: 38

    Topics: Bone Neoplasms; Breast Neoplasms; Humans; Hydroxyproline; Male; Neoplasm Metastasis; Prostatic Neopl

1962
CORRELATION OF URINARY HYDROXYPROLINE, SERUM ALKALINE PHOSPHATASE AND SKELETAL CALCIUM TURNOVER.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Alkaline Phosphatase; Bone and Bones; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Calcium; Geri

1964
URINARY HYDROXYPROLINE EXCRETION IN METASTATIC CANCER OF BONE.
    The New England journal of medicine, 1964, 08-06, Volume: 271

    Topics: Acid Phosphatase; Biomedical Research; Bone Neoplasms; Breast Neoplasms; Collagen; Humans; Hydroxypr

1964
URINARY HYDROXYPROLINE IN DISEASES INVOLVING BONE AND CALCIUM METABOLISM.
    The Medical journal of Australia, 1964, Jun-27, Volume: 1

    Topics: Acute Kidney Injury; Alkaline Phosphatase; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Calcium;

1964
EXCRETION OF PYROPHOSPHATE IN DISORDERS OF BONE METABOLISM.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Bone Neoplasms; Bone Resorption; Chromatography; Diphosphates; Fluids and Secretions; Humans; Hydrox

1965
[Urinary hydroxy-proline in patients with urolithiasis].
    Hinyokika kiyo. Acta urologica Japonica, 1966, Volume: 12, Issue:10

    Topics: Bone Neoplasms; Decalcification, Pathologic; Fractures, Bone; Humans; Hydroxyproline; Hyperparathyro

1966
[Hydroxyproline excretion in the urine in destructive bone processes].
    Wiener klinische Wochenschrift, 1967, Jan-13, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Bone and Bones; Bone Diseases; Bone Neoplasms; Collagen; Female; Humans; Hydroxyp

1967
[A method of fractionating urinary peptides containing hydroxyproline].
    Clinica chimica acta; international journal of clinical chemistry, 1967, Volume: 16, Issue:3

    Topics: Acromegaly; Arthritis, Rheumatoid; Bone Neoplasms; Chemistry, Clinical; Chromatography, Ion Exchange

1967
Urinary hydroxyproline excretion in orthopedic disease, with special reference to systemic bone disease and bone tumor (secondary report).
    Nagoya journal of medical science, 1967, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Bone Diseases; Bone Neoplasms; Child; Female; Humans; Hydroxyproline; Male

1967
Multiple biological markers and breast carcinoma: a preliminary study in the detection of recurrent disease after primary therapy.
    Journal of surgical oncology, 1981, Volume: 18, Issue:1

    Topics: Aminoisobutyric Acids; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Creatinine; Femal

1981
[Clinical value of enzyme parameter combinations in the diagnosis of metastases].
    Radiobiologia, radiotherapia, 1983, Volume: 24, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Female; gamma-Glutamyltran

1983
[Urinary hydroxyproline excretion as a marker of bone metastasis in prostatic cancer].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1983, Volume: 74, Issue:1

    Topics: Aged; Bone Neoplasms; Humans; Hydroxyproline; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Ne

1983
Use of urinary hydroxyproline excretion as a tumor marker in diagnosis and follow-up of prostatic carcinoma.
    The Prostate, 1983, Volume: 4, Issue:4

    Topics: Bone Neoplasms; Castration; Creatinine; Estrogens; Follow-Up Studies; Humans; Hydroxyproline; Male;

1983
Detection of bone metastases in patients with breast cancer.
    Invasion & metastasis, 1982, Volume: 2, Issue:3

    Topics: Biopsy, Needle; Bone and Bones; Bone Marrow Examination; Bone Neoplasms; Breast Neoplasms; Diphospho

1982
Assessment of biochemical tests for bone and liver involvement in malignant lymphoma patients.
    Cancer, 1980, Mar-15, Volume: 45, Issue:6

    Topics: Adult; Alkaline Phosphatase; Bone Neoplasms; Female; Humans; Hydroxyproline; Liver Neoplasms; Lympho

1980
Relative contribution of humoral and metastatic factors to the pathogenesis of hypercalcaemia in malignancy.
    British medical journal (Clinical research ed.), 1984, May-12, Volume: 288, Issue:6428

    Topics: Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Carcinoma, Bronchogenic;

1984
Hypercalcemia of malignancy: treatment with intravenous dichloromethylene diphosphonate.
    Annals of internal medicine, 1981, Volume: 94, Issue:3

    Topics: Adult; Aged; Bone Neoplasms; Bone Resorption; Calcium; Clodronic Acid; Diarrhea; Diphosphonates; Dru

1981
Use of an antiosteolytic agent in treatment of patients with bone metastases from breast cancer.
    European journal of cancer, 1980, Volume: Suppl 1

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Doxorubicin; Drug Therapy, Combination; Fema

1980
[Biochemical diagnosis of bone metastases].
    Vnitrni lekarstvi, 1984, Volume: 30, Issue:11

    Topics: Bone Neoplasms; Clinical Enzyme Tests; Humans; Hydroxyproline; Minerals

1984
Study of serum and urine hydroxyproline level of patients with prostatic cancer.
    European urology, 1984, Volume: 10, Issue:6

    Topics: Aged; Bone Neoplasms; Humans; Hydroxyproline; Male; Middle Aged; Prostatic Neoplasms

1984
[Urinary hydroxyproline excretion as a marker of bone metastasis in prostatic cancer (II): Correlation between extent of metastatic lesions in whole body bone scintigraphy of patients with prostatic cancer and tumor markers in blood and urine].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1984, Volume: 75, Issue:1

    Topics: Aged; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Creatine; Humans; Hydroxyproline; Male;

1984
The postabsorptive hydroxyproline in the long-term evaluation of patients with breast cancer.
    Cancer, 1983, Oct-15, Volume: 52, Issue:8

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Middle Aged; Radiogra

1983
Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer.
    Archives of internal medicine, 1983, Volume: 143, Issue:10

    Topics: Bone Neoplasms; Breast Neoplasms; Collagen; Dialysis; Female; Hodgkin Disease; Humans; Hydroxyprolin

1983
[Value of the determination of urinary hydroxyproline in the detection of bone metastases].
    Medicina clinica, 1983, Sep-17, Volume: 81, Issue:7

    Topics: Adult; Aged; Bone Neoplasms; Female; Humans; Hydroxyproline; Male; Middle Aged; Radiography

1983
Urinary hydroxyproline levels in patients with prostatic carcinoma.
    International urology and nephrology, 1983, Volume: 15, Issue:3

    Topics: Aged; Bone Neoplasms; Humans; Hydroxyproline; Male; Middle Aged; Prostatic Neoplasms

1983
[Urinary hydroxyproline and cancer of the breast].
    Revista espanola de oncologia, 1983, Volume: 30, Issue:1

    Topics: Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Humans; Hydroxyproline

1983
Total and nondialyzable hydroxyproline excretion in Stage D2 prostate cancer.
    Cancer, 1984, Jan-01, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Bone Neoplasms; Collagen; Creatinine; Dialysis; Humans; Hydroxyproline; Male; Neopla

1984
Urinary hydroxyproline and prognosis in human breast cancer.
    The British journal of surgery, 1984, Volume: 71, Issue:2

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Humans; Hydroxyproline; Middle Ag

1984
[Hydroxyproline and bone metastases].
    Medicina clinica, 1984, Feb-25, Volume: 82, Issue:7

    Topics: Bone Neoplasms; Humans; Hydroxyproline

1984
Serial spot hydroxyproline/creatinine ratios in metastatic prostatic cancer.
    The Journal of urology, 1983, Volume: 129, Issue:2

    Topics: Acid Phosphatase; Adenocarcinoma; Alkaline Phosphatase; Bone Neoplasms; Creatinine; Humans; Hydroxyp

1983
Assessment of response of bone metastases to systemic treatment in patients with breast cancer.
    Cancer, 1983, Aug-15, Volume: 52, Issue:4

    Topics: Alkaline Phosphatase; Aminoglutethimide; Antineoplastic Agents; Bone Marrow; Bone Neoplasms; Breast

1983
Characteristics of the newly derived human chondrosarcoma cell line OSHU-1: observations on osteoinduction.
    Journal of the National Cancer Institute, 1980, Volume: 65, Issue:2

    Topics: Animals; Bone Neoplasms; Cell Line; Chondrosarcoma; Humans; Hydroxyproline; Male; Mice; Mice, Nude;

1980
[Effects of synthetic salmon calcitonin in the treatment of bone lesions of the neoplastic type].
    Tumori, 1982, Feb-28, Volume: 68, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Animals; Bone Neoplasms; Calcitonin; Calcium; Female; Humans; Hyd

1982
Hydroxyproline excretion in the detection of occult bone metastases from breast cancer.
    Oncology, 1982, Volume: 39, Issue:5

    Topics: Bone and Bones; Bone Neoplasms; Breast Neoplasms; Creatinine; Evaluation Studies as Topic; Female; H

1982
Urinary hydroxyproline excretion as a marker of bone metastasis in prostatic cancer.
    The Tohoku journal of experimental medicine, 1982, Volume: 137, Issue:4

    Topics: Bone Neoplasms; Creatinine; Humans; Hydroxyproline; Male; Prostatic Neoplasms

1982
[Hydroxyprolinuria in relation to bone metastases in patients with breast cancer].
    Revista espanola de oncologia, 1980, Volume: 27, Issue:1

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Middle Aged

1980
[Urinary and serum hydroxyproline in the diagnosis of bone metastases of prostatic cancer].
    Schweizerische medizinische Wochenschrift, 1981, Feb-21, Volume: 111, Issue:8

    Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcium; Creatinine; Humans; Hydroxypr

1981
[Serum hydroxyproline parameter of collagen metabolism (author's transl)].
    Wiener klinische Wochenschrift, 1981, Mar-06, Volume: 93, Issue:5

    Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Collagen; Hip Prosthesis; Humans;

1981
Postabsorptive urinary hydroxyproline test in patients with metastatic bone disease from breast cancer.
    Archives of internal medicine, 1981, Volume: 141, Issue:11

    Topics: Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Gelatin; Humans; Hydroxyproline

1981
[Modern developments in the diagnosis and therapy of prostatic cancer].
    Zeitschrift fur Urologie und Nephrologie, 1981, Volume: 74, Issue:7

    Topics: Acid Phosphatase; Age Factors; Bone Neoplasms; Cyclophosphamide; Estrogens; Humans; Hydroxyproline;

1981
Urinary excretion of glycosaminoglycans and hydroxyproline in Paget's disease of bone, compared with neoplastic invasion of bone.
    Journal of clinical pathology, 1981, Volume: 34, Issue:10

    Topics: Aged; Bone Neoplasms; Creatinine; Female; Glycosaminoglycans; Humans; Hydroxyproline; Male; Middle A

1981
Study of hydroxyproline excretion in patients with prostatic cancer.
    International urology and nephrology, 1981, Volume: 13, Issue:3

    Topics: Bone Neoplasms; Humans; Hydroxyproline; Male; Prostatic Neoplasms

1981
An automatic technique for the routine fractionation of the urinary hydroxyproline containing peptides.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Jan-15, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Autoanalysis; Bone Neoplasms; Chemical Fractionation; Child; Female; Humans; Hydr

1980
Urinary hydroxyproline excretion in myelofibrosis.
    Blood, 1980, Volume: 55, Issue:3

    Topics: Bone Neoplasms; Collagen; Fibroblasts; Humans; Hydroxyproline; Neoplasm Metastasis; Neoplasms; Prima

1980
Urinary hydroxyproline excretion as a marker of osseous metastasis in carcinoma of the prostate.
    The Journal of urology, 1980, Volume: 123, Issue:5

    Topics: Bone Neoplasms; Carcinoma; Humans; Hydroxyproline; Male; Neoplasm Staging; Prostatic Neoplasms

1980
[Urinary hydroxyproline in advanced breast carcinoma and response to treatment with medroxyprogesterone acetate (MAP) in high doses].
    Minerva medica, 1980, Sep-01, Volume: 71, Issue:31

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Medroxyprogesterone;

1980
[Hydroxyprolinuria and bone metastases of breast cancer].
    Tumori, 1980, Apr-30, Volume: 66, Issue:2

    Topics: Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Follow-Up Studies; Humans; Hydroxyproline

1980
Collagen cross-link metabolites in urine as markers of bone metastases in prostatic carcinoma.
    The Journal of urology, 1994, Volume: 151, Issue:4

    Topics: Aged; Amino Acids; Biomarkers, Tumor; Bone Neoplasms; Circadian Rhythm; Collagen; Creatinine; Humans

1994
[Correlation between bone gammagraphy and biochemical parameters in bone turnover in patients with prostate cancer].
    Actas urologicas espanolas, 1994, Volume: 18, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Bone Neoplasms; Creatinine; Humans; Hydroxyproline;

1994
The effect of combined intravenous and oral clodronate treatment on bone pain in patients with metastatic prostate cancer.
    Annales chirurgiae et gynaecologiae, 1994, Volume: 83, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Bone Neoplasms; Bone Resorption; Clodronic Acid; Dose

1994
The anti-osteoporotic activity of amine-carboxyboranes in rodents.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:3

    Topics: Animals; Bone Neoplasms; Boranes; Calcium; Female; Hydroxyproline; In Vitro Techniques; Male; Mice;

1995
[Biphosphonates and multiple myeloma].
    Bulletin du cancer, 1993, Volume: 80, Issue:10 Suppl

    Topics: Animals; Bone Neoplasms; Calcium; Diphosphonates; Humans; Hydroxyproline; Hypercalcemia; Multiple My

1993
Changes of bone metabolic markers in patients with bone metastases: clinical significance in assessing bone response to chemotherapy.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:8

    Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Biom

1993
Biochemical markers for detecting bone metastases in patients with breast cancer.
    Clinical chemistry, 1993, Volume: 39, Issue:1

    Topics: Alkaline Phosphatase; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neo

1993
Comparative evaluation of markers of bone resorption in patients with breast cancer-induced osteolysis before and after bisphosphonate therapy.
    British journal of cancer, 1997, Volume: 75, Issue:3

    Topics: Adult; Aged; Amino Acids; Analysis of Variance; Biomarkers; Bone Neoplasms; Bone Resorption; Breast

1997
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:4

    Topics: Alendronate; Antineoplastic Agents; Bone Neoplasms; Collagen; Gelatinases; Humans; Hydroxyproline; M

1998
Biological markers of human tumors and monitoring of cancer treatment.
    Archiv fur Geschwulstforschung, 1979, Volume: 49, Issue:6

    Topics: Alkaline Phosphatase; alpha-Fetoproteins; Bone Neoplasms; Carcinoembryonic Antigen; Choriocarcinoma;

1979
Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases.
    European journal of clinical investigation, 1978, Volume: 8, Issue:6

    Topics: Acromegaly; Adult; Alkaline Phosphatase; Bone Diseases; Bone Neoplasms; Female; Humans; Hydroxyproli

1978
[Current status of diagnosis and stage classification of prostatic carcinoma].
    Medizinische Klinik, 1977, Oct-07, Volume: 72, Issue:40

    Topics: Aged; Biopsy, Needle; Bone Neoplasms; Humans; Hydroxyproline; Lymphatic Metastasis; Male; Middle Age

1977
Nutrition and breast cancer.
    Journal of human nutrition, 1979, Volume: 33, Issue:1

    Topics: Animals; Ascorbic Acid; Bone Neoplasms; Breast Neoplasms; Calcium; Dietary Fats; Feeding Behavior; F

1979
Urinary excretion of hydroxyproline, hydroxylysine and hydroxylysine glycosides by patients with Paget's disease of bone and carcinoma with metastases in bone.
    Clinica chimica acta; international journal of clinical chemistry, 1979, Mar-15, Volume: 92, Issue:3

    Topics: Bone Neoplasms; Collagen; Glycosides; Humans; Hydroxylysine; Hydroxyproline; Neoplasm Metastasis; Os

1979
Urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases.
    Current problems in clinical biochemistry, 1979, Issue:9

    Topics: Bone Neoplasms; Humans; Hydroxyproline; Male; Neoplasm Metastasis; Prostatic Neoplasms; Radiography

1979
[Evaluation of hydroxyproline excretion in the urine (UHP) in prostate carcinoma].
    Zeitschrift fur Urologie und Nephrologie, 1979, Volume: 72, Issue:3

    Topics: Aged; Bone Neoplasms; Carcinoma; Castration; False Negative Reactions; False Positive Reactions; Hum

1979
Total urinary and free serum hydroxyproline in metastatic bone disease.
    British journal of cancer, 1979, Volume: 39, Issue:3

    Topics: Adult; Aged; Bone Neoplasms; Creatinine; Female; Humans; Hydroxyproline; Male; Middle Aged; Neoplasm

1979
Collagenolytic activity of eosinophilic granuloma in vitro.
    Experientia, 1979, Sep-15, Volume: 35, Issue:9

    Topics: Bone Neoplasms; Cells, Cultured; Child; Collagen; Eosinophilic Granuloma; Humans; Hydroxyproline

1979
Urinary hydroxyproline excretion in carcinoma of the prostate. A comparison of 4 different modes of assessment and its role as a marker.
    British journal of urology, 1979, Volume: 51, Issue:6

    Topics: Aged; Bone Neoplasms; Creatinine; Follow-Up Studies; Humans; Hydroxyproline; Male; Middle Aged; Pros

1979
Urine hydroxyproline excretion--a marker of bone metastases in prostatic carcinoma.
    British journal of urology, 1977, Volume: 49, Issue:7

    Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcium; Creatinine; Humans; Hydroxypr

1977
Urinary excretion of glycosaminoglycans in disseminated neoplasm.
    Journal of clinical pathology, 1978, Volume: 31, Issue:5

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Creatinine; Female; Glycosaminoglycans; Hexosamin

1978
Three-centre study on urinary hydroxyproline excretion in cancer of the breast.
    British journal of cancer, 1978, Volume: 37, Issue:6

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Methods; Middle Aged;

1978
Relation between urine zinc and hydroxyproline in rheumatoid arthritis and bone diseases.
    The Journal of rheumatology, 1978,Winter, Volume: 5, Issue:4

    Topics: Arthritis, Rheumatoid; Bone Neoplasms; Humans; Hydroxyproline; Neoplasm Metastasis; Osteitis Deforma

1978
[Variable behavior of urinary hydroxyproline in breast cancer with osseous metastases].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1978, Volume: 14, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline

1978
Urinary hydroxyproline in the management of breast cancer.
    World journal of surgery, 1977, Volume: 1, Issue:3

    Topics: Bone Neoplasms; Breast Neoplasms; Castration; Diethylstilbestrol; Female; Humans; Hydroxyproline; Ne

1977
A biochemical approach to the staging of human breast cancer.
    Cancer, 1977, Volume: 40, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; C-Reactive Protein; Calcitonin;

1977
[Hydroxyproline in the diagnosis of bone metastases in breast cancer].
    Schweizerische medizinische Wochenschrift, 1977, Jul-16, Volume: 107, Issue:28

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Creatinine; False Negative Reactions; Female; Humans;

1977
[Collagen metabolism in children and adolescents with diseases of the skeletal system].
    Ortopediia travmatologiia i protezirovanie, 1977, Issue:7

    Topics: Adolescent; Adult; Bone Diseases; Bone Neoplasms; Child; Child, Preschool; Collagen; Female; Humans;

1977
Relevance of hydroxyproline excretion to bone metastasis in breast cancer.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Hu

1976
Early morning hydroxyproline excretion in patients with breast cancer.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Bone Neoplasms; Breast Neoplasms; Creatine; Female; Humans; Hydroxyproline; Neoplasm Metastasis; Tim

1976
Failure of indomethacin to reduce hypercalcemia in patients with breast cancer.
    Prostaglandins, 1976, Volume: 12, Issue:6

    Topics: Aspirin; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Humans; Hydroxyproline; Hype

1976
Hydroxyproline excretion in patients with breast cancer and response to treatment.
    British medical journal, 1975, Apr-26, Volume: 2, Issue:5964

    Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Calcium; Ethinyl Estradiol; Female; Humans;

1975
Letter: Predictive value of hydroxyproline: creatinine ratio in advanced breast cancer.
    British medical journal, 1975, Jun-07, Volume: 2, Issue:5970

    Topics: Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Humans; Hydroxyproline; Neoplasm Metastasis; R

1975
[Diagnosis of bone metastases with special reference to the methods of clinical chemistry].
    Die Medizinische Welt, 1975, Aug-08, Volume: 26, Issue:31-32

    Topics: Alkaline Phosphatase; Bone Neoplasms; Calcium; Humans; Hydroxyproline; Methods; Neoplasm Metastasis;

1975
The hypronosticon test in breast cancer.
    Clinical oncology, 1975, Volume: 1, Issue:1

    Topics: Adult; Aged; Body Surface Area; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Creatinine; Female

1975
A column chromatography fractionation of the hydroxyproline-containing urinary peptides with continuous automatic detection.
    Annales de biologie clinique, 1975, Volume: 33, Issue:5

    Topics: Autoanalysis; Bone Neoplasms; Chemical Fractionation; Chromatography; Chromatography, Gel; Chromatog

1975
[Chromatographic analysis of urinary amino acids in Paget's disease. II : clinical study].
    Revue du rhumatisme et des maladies osteo-articulaires, 1976, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Amino Acids; Bone Diseases; Bone Neoplasms; Calcitoni

1976
[Clinical evaluation of bone turnover in patients with bone metastasis of various cancer of urogenital tract].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1990, Volume: 81, Issue:8

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Calcifediol; Calcium; Hu

1990
[Bone turnover markers in tumor pathology with bone involvement].
    Medicina clinica, 1990, Apr-07, Volume: 94, Issue:13

    Topics: Adult; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Neoplasms; Female; Humans; Hydro

1990
[Use of urinary hydroxyproline excretion as a marker of bone metastases in prostatic cancer (1)].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:12

    Topics: Bone Neoplasms; Humans; Hydroxyproline; Male; Prostatic Hyperplasia; Prostatic Neoplasms

1985
[The value of the free hydroxyproline and the N-acetyl-beta- glucosaminidase for the observation of the course of malignant tumors].
    Folia haematologica (Leipzig, Germany : 1928), 1986, Volume: 113, Issue:3

    Topics: Acetylglucosaminidase; Bone Neoplasms; Breast Neoplasms; Female; Hexosaminidases; Hodgkin Disease; H

1986
A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients.
    Cancer, 1989, May-15, Volume: 63, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Follow-U

1989
[Response of bone metastases to medical treatment: definition of evaluation criteria and classification trials].
    Bulletin du cancer, 1989, Volume: 76, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Biomarkers, Tumor; Bone Neoplasms; Evaluation Studies as Top

1989
Bone alkaline phosphatase isoenzyme and urinary hydroxyproline in healthy subjects, patients with osteolytic metastases, and patients with primary hyperparathyroidism.
    Neoplasma, 1989, Volume: 36, Issue:4

    Topics: Adult; Alkaline Phosphatase; Biomarkers; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Breast N

1989
Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis.
    British journal of urology, 1985, Volume: 57, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Bone and Bones; Bone Neoplasms; Calcium; Calcium-Binding Proteins; Hum

1985
Treatment of malignancy-associated hypercalcemia with intravenous aminohydroxypropylidene diphosphonate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Calcium; Cyclic AMP; Diphosphonates; Female; Head and

1986
Skeletal surveys in multiple myeloma. Radiologic-clinical correlation.
    Skeletal radiology, 1986, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Female; Humans; Hydroxyproline; Immu

1986
Hydroxyproline as a marker for following patients with metastatic prostate cancer.
    The Journal of urology, 1988, Volume: 139, Issue:1

    Topics: Bone Neoplasms; Buserelin; Creatinine; Flutamide; Follow-Up Studies; Gonadotropin-Releasing Hormone;

1988
[Effects of etidronate disodium (EHDP) on urogenital malignancies with bone metastasis: a multicentered collaborative evaluation].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:3

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Calcium; Drug Evaluat

1988
Hypercalcemia in malignancies: treatment with dichloromethylene diphosphonate (Cl2MDP).
    Tumori, 1985, Feb-28, Volume: 71, Issue:1

    Topics: Adult; Aged; Bone Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Drug Evaluation; Female; Human

1985
Serum osteocalcin concentration in patients with prostatic cancer.
    American journal of clinical oncology, 1988, Volume: 11 Suppl 2

    Topics: 1-Carboxyglutamic Acid; Acid Phosphatase; Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers,

1988
Value of urinary hydroxyproline and bone isoenzyme of alkaline phosphatase in the early detection and follow-up of bone metastasis in breast cancer patients.
    Bulletin du cancer, 1988, Volume: 75, Issue:6

    Topics: Alkaline Phosphatase; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Female; Follow-Up Studies

1988
[Determination of serum proline iminopeptidase activity using a fluorescent substrate in patients with Paget's disease and prostatic bone metastases. Preliminary results].
    Pathologie-biologie, 1986, Volume: 34, Issue:4

    Topics: Adult; Aminopeptidases; Bone Neoplasms; Coumarins; Female; Humans; Hydroxyproline; Male; Middle Aged

1986
[Comprehensive diagnostic approaches to tumor metastases in the skeleton. V. The relation of biochemical indicators to age in the diagnosis of bone metastases of stage II carcinoma of the breast. Analysis of additional diagnostic and prognostic parameters
    Casopis lekaru ceskych, 1987, Aug-14, Volume: 126, Issue:33

    Topics: Age Factors; Alkaline Phosphatase; Analysis of Variance; Bone Neoplasms; Breast Neoplasms; Carcinoma

1987
[Detection of bone metastases using hydroxyproline excretion].
    Radiobiologia, radiotherapia, 1986, Volume: 27, Issue:1

    Topics: Bone Neoplasms; Humans; Hydroxyproline

1986
Gallium nitrate inhibits accelerated bone turnover in patients with bone metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Bone Development; Bone Neoplasms; Bone Resorption; Calcium; Fema

1987
Efficacy of aminohydroxypropylidene diphosphonate in the treatment of malignancy-associated hypercalcaemia.
    The Medical journal of Australia, 1987, Mar-02, Volume: 146, Issue:5

    Topics: Adenosine Diphosphate; Bone Neoplasms; Breast Neoplasms; Calcium; Drug Evaluation; Female; Humans; H

1987
Parathyroid function and vitamin D status in patients with bone metastases of prostatic origin.
    Mineral and electrolyte metabolism, 1985, Volume: 11, Issue:2

    Topics: Aged; Alkaline Phosphatase; Bone Neoplasms; Calcifediol; Calcitriol; Calcium; Humans; Hydroxyproline

1985
Biological characterization of human bone tumors. V. Zonal characterization of osteosarcoma: topological biochemical analysis correlated with morphology.
    Pathology, research and practice, 1985, Volume: 180, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Bone Neoplasms; Collagen; Glucuronidase; Hexosamines; Humans

1985
Mechanism of malignant hypercalcaemia in carcinoma of the breast.
    British medical journal (Clinical research ed.), 1985, Sep-21, Volume: 291, Issue:6498

    Topics: Absorption; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Humans; Hydroxyproline; H

1985
[The clinical significance of urinary hydroxyproline determinations (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1972, Volume: 10, Issue:5

    Topics: Alkaline Phosphatase; Animals; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Burns; Carbon R

1972
Effects of calcitonin in metastatic bone carcinoma, osteoporosis, polyostotic fibrous dysplasia and hypercalcemia.
    Endocrinologia japonica, 1971, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcitonin; Calcium; Child, Presc

1971
[Urinary pyrophosphate and hydroxyproline in bone tumors].
    Nihon Seikeigeka Gakkai zasshi, 1969, Volume: 43, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Animals; Bone Neoplasms; Carcinoma 256, Walker; Child; Child,

1969
Urinary hydroxyproline, serum alkaline phosphatase, calcium and phosphorus in patients with bone neoplasms.
    Polish medical journal, 1972, Volume: 11, Issue:4

    Topics: Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Carcinoma, Intraductal, Noninfiltra

1972
[Urinary hydroxyproline correlated with quantitative bone histological data. Attempted physiopathological interpretation].
    Revue du rhumatisme et des maladies osteo-articulaires, 1972, Volume: 39, Issue:2

    Topics: Alkaline Phosphatase; Biopsy; Bone and Bones; Bone Diseases; Bone Neoplasms; Bone Resorption; Humans

1972
Hydroxyproline in the early diagnosis of bone metastases in prostatic cancer.
    Scandinavian journal of urology and nephrology, 1974, Volume: 8, Issue:2

    Topics: Administration, Oral; Aged; Bone Neoplasms; Diethylstilbestrol; Humans; Hydroxyproline; Injections,

1974
Multiple intraosseous lipomas with type-IV hyperlipoproteinemia. A case report.
    The Journal of bone and joint surgery. American volume, 1974, Volume: 56, Issue:8

    Topics: Amino Acids; Ankle; Blood Protein Disorders; Bone Neoplasms; Cholesterol; Female; Glycosaminoglycans

1974
Effect of dibutyryl-cyclic AMP on collagen and non-collagen protein synthesis in cultured human cells.
    Connective tissue research, 1974, Volume: 2, Issue:3

    Topics: Adult; Animals; Bone and Bones; Bone Neoplasms; Bucladesine; Butyrates; Carbon Radioisotopes; Cattle

1974
The effects of calcitonin on the metabolic disturbances surrounding widespread bony metastases.
    Acta endocrinologica, 1974, Volume: 76, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Calcitonin

1974
Effect of calcitonin and hexestrol on urinary excretion of hydroxyproline in a patient with prostatic cancer and bone metastases.
    Endocrinologia japonica, 1974, Volume: 21, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; Bone Neoplasms; Calcitonin; Calcium; Hexestrol; Humans; Hydr

1974
Urinary hydroxyproline and plasma mucoprotein as an indication of the presence of bone metastases.
    Oncology, 1974, Volume: 30, Issue:3

    Topics: Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Female; Humans; Hydroxyprolin

1974
Leucocyte ascorbic acid and urinary hydroxyproline levels in patients bearing breast cancer with skeletal metastases.
    European journal of cancer, 1974, Volume: 10, Issue:8

    Topics: Ascorbic Acid; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Leukocytes; Male; N

1974
'Early' breast cancer, bone scanning, and the urinary excretion of hydroxyproline.
    The British journal of surgery, 1973, Volume: 60, Issue:4

    Topics: Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Methods; Neoplasm Metastasis; Radi

1973
Urinary hydroxyproline excretion in early and advanced breast cancer-a sequential study.
    The British journal of surgery, 1973, Volume: 60, Issue:10

    Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Collagen;

1973
Role of strontium (85Sr) scintigraphy in the clinical analysis of bone diseases.
    Annales chirurgiae et gynaecologiae Fenniae, 1973, Volume: 62, Issue:3

    Topics: Adult; Aged; Bone and Bones; Bone Diseases; Bone Neoplasms; Female; Fractures, Bone; Humans; Hydroxy

1973
[Hydroxyprolinuria in skeletal diseases: its correlation with other parameters of bone metabolism].
    Schweizerische medizinische Wochenschrift, 1972, Feb-05, Volume: 102, Issue:5

    Topics: Alkaline Phosphatase; Bone and Bones; Bone Diseases; Bone Neoplasms; Calcium; Humans; Hydroxyproline

1972
Hydroxyproline.
    Postgraduate medicine, 1972, Volume: 51, Issue:5

    Topics: Bone and Bones; Bone Diseases; Bone Neoplasms; Burns; Collagen; Collagen Diseases; Fibrous Dysplasia

1972
Urinary hydroxyproline excretion in carcinoma of the breast.
    British journal of experimental pathology, 1972, Volume: 53, Issue:3

    Topics: Adult; Bone Neoplasms; Breast Neoplasms; Creatinine; Female; Humans; Hydroxyproline; Middle Aged; Ne

1972
Bone collagen and calcium metabolism in normocalcemic and hypercalcemic patients with breast cancer.
    Cancer, 1971, Volume: 27, Issue:5

    Topics: Adult; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Calcium; Collagen; Co

1971
Urinary hydroxyproline excretion in patients with breast cancer.
    The British journal of surgery, 1971, Volume: 58, Issue:11

    Topics: Bone Neoplasms; Breast Neoplasms; Hydroxyproline; Neoplasm Metastasis

1971
[Multiple enchondromatosis].
    Padiatrie und Grenzgebiete, 1971, Volume: 10, Issue:2

    Topics: Bone Neoplasms; Child; Diagnosis, Differential; Humans; Hydroxyproline; Male; Osteochondrodysplasias

1971
[Creatinine-hydroxyproline index in healthy subjects, in hyperthyroidism and in bone neoplasms].
    Polskie Archiwum Medycyny Wewnetrznej, 1971, Volume: 47, Issue:3

    Topics: Adult; Aged; Bone Neoplasms; Creatinine; Female; Graves Disease; Humans; Hydroxyproline; Hyperthyroi

1971
[Total urinary hydroxyproline excretion in bone tumors].
    Nihon Seikeigeka Gakkai zasshi, 1967, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Bone Neoplasms; Child; Collagen; Female; Humans; Hydroxyproline; Male; Middle Age

1967
Studies on urinary hydroxyproline.
    Fukushima journal of medical science, 1969, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Bone Diseases; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Hyd

1969
[Correlation of hydroxyprolinuria and other parameters of bone metabolism].
    Helvetica medica acta. Supplementum, 1970

    Topics: Bone and Bones; Bone Diseases; Bone Neoplasms; Collagen; Humans; Hydroxyproline; Osteoporosis

1970
[Urinary hydroxyproline during secondary bone cancers].
    Pathologie et biologie, 1966, Volume: 14, Issue:3

    Topics: Bone Neoplasms; Humans; Hydroxyproline; Urine

1966
[Study of urinary hydroxyproline in osteopathies].
    Pathologie et biologie, 1966, Volume: 14, Issue:21

    Topics: Acromegaly; Adult; Aged; Bone Neoplasms; Female; Humans; Hydroxyproline; Hyperparathyroidism; Hypert

1966
[Measurement of collagen catabolism in the diagnosis of bone metastases and in the evaluation of therapeutic success].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1969, Volume: 75

    Topics: Adult; Aged; Bone Neoplasms; Collagen; Diethylstilbestrol; Female; Humans; Hydroxyproline; Male; Mid

1969
[Plasma free amino acids in malignant bone tumors and in healthy subjects].
    Clinica chimica acta; international journal of clinical chemistry, 1970, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Amino Acids; Bone Neoplasms; Calcium; Chromatography;

1970
[Diagnosis of osseous involvement in Hodgkin's disease].
    Deutsche medizinische Wochenschrift (1946), 1970, May-01, Volume: 95, Issue:18

    Topics: Adolescent; Adult; Aged; Bone Neoplasms; Collagen; Female; Hodgkin Disease; Humans; Hydroxyproline;

1970
[Hydroxyproline in generalized bone diseases].
    Deutsches medizinisches Journal, 1970, Jun-20, Volume: 21, Issue:12

    Topics: Bone Diseases; Bone Neoplasms; Humans; Hydroxyproline; Male; Middle Aged; Neoplasm Metastasis

1970
["Collagen-like protein" (CLP) and collagen antibodies in the serum of chronic polyarthritis and non-rheumatic diseases of connective tissue].
    Klinische Wochenschrift, 1970, Mar-15, Volume: 48, Issue:6

    Topics: Aged; Antibodies; Antibody Specificity; Arthritis, Rheumatoid; Bone Neoplasms; Chronic Disease; Coll

1970
[Investigation on urinary hydroxyproline--influence of skin collagen on urinary hydroxyproline and its adjustment by hydroxyproline--creatinine ratio].
    Nihon Seikeigeka Gakkai zasshi, 1970, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Age Factors; Animals; Bone Neoplasms; Child; Child, Preschool; Collagen; Creatini

1970
[Urinary hydroxyproline excretion in generalized bone diseases].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1967, Volume: 48, Issue:10

    Topics: Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Female; Hum

1967
Fluoride effect on bone in plasma cell myeloma.
    Archives of internal medicine, 1968, Volume: 121, Issue:2

    Topics: Bone and Bones; Bone Neoplasms; Calcium; Cyclophosphamide; Fluorides; Humans; Hydroxyproline; Ilium;

1968
The significance of hydroxyprolinuia for the proof of bone metastases of tumours.
    Neoplasma, 1968, Volume: 15, Issue:4

    Topics: Bone Neoplasms; Breast Neoplasms; Humans; Hydroxyproline; Lung Neoplasms; Neoplasm Metastasis; Radio

1968
A rapid serum screening test for increased osteoblastic activity.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Blood Chemical Analysis; Bone and Bones; Bone Development;

1968
[Urinary hydroxyproline excretion before and after hypophysectomy in patients with bone metastases from breast cancer].
    Ugeskrift for laeger, 1968, Oct-17, Volume: 130, Issue:42

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Hypophysectomy; Middl

1968
Total urinary hydroxyproline excretion before and after hypophysectomy in patients with bone metastases from breast carcinoma.
    Acta endocrinologica, 1968, Volume: 59, Issue:3

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Carcinoma; Chemistry,

1968
[Measurement of collagen metabolism in the diagnosis of bone metastases].
    Schweizerische medizinische Wochenschrift, 1969, Mar-08, Volume: 99, Issue:10

    Topics: Aged; Bone Neoplasms; Collagen; Female; Humans; Hydroxyproline; Male; Methods; Middle Aged; Neoplasm

1969
Urinary hydroxyproline excretion in patients with cancer.
    Cancer, 1969, Volume: 24, Issue:2

    Topics: Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Collagen; Creatine; Female; Humans;

1969
Hydroxyproline excretion in malignant neoplastic disease.
    Archives of internal medicine, 1966, Volume: 118, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Carcinoma, Bronchogenic; Female

1966
Urinary hydroxyproline and calcium metabolism in patients with cancer.
    The New England journal of medicine, 1966, Aug-11, Volume: 275, Issue:6

    Topics: Bone Neoplasms; Calcium; Humans; Hydroxyproline; Hypercalcemia; Neoplasm Metastasis; Neoplasms; Urin

1966
[Hydroxyproline excretion as an index for the evaluation of metabolic bone changes].
    Beitrage zur Orthopadie und Traumatologie, 1966, Volume: 13, Issue:10

    Topics: Adult; Animals; Bone Neoplasms; Breast Neoplasms; Child; Female; Humans; Hydroxyproline; Metabolic D

1966
[On the excretion of bound hydroxyproline as an expression of changes in the organic cartilage and bone matrix].
    Zeitschrift fur arztliche Fortbildung, 1966, May-15, Volume: 60, Issue:10

    Topics: Adolescent; Bone and Bones; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Cartilage; Ehlers-Danlo

1966