hydroxyproline has been researched along with Blood Pressure, High in 72 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 7.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| "We investigated whether the substrate for nitric oxide synthesis L-arginine is able to modify hypertension and left ventricular hypertrophy development induced by chronic blockade of nitric oxide synthase activity by NG-nitro-L-arginine-methyl ester (L-NAME)." | 7.73 | L-arginine fails to protect against myocardial remodelling in L-NAME-induced hypertension. ( Babal, P; Bernatova, I; Gvozdjakova, A; Krajcirovicova, K; Kucharska, J; Luptak, I; Matuskova, J; Pechanova, O; Simko, F; Simko, J; Sumbalova, Z, 2005) |
| "To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 7.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
| "The effects of long-term treatment with verapamil on blood pressure, cardiac hypertrophy and collagen content, collagen concentration and prolyl hydroxylase activity were studied in spontaneously hypertensive rats (SHR)." | 7.67 | Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats. ( Ruskoaho, HJ; Savolainen, ER, 1985) |
| "The effect of angiotensin II-induced hypertension on selected biochemical parameters was studied in Sprague-Dawley rats." | 7.67 | Transmural distribution of biochemical markers of total protein and collagen synthesis, myocardial contraction speed and capillary density in the rat left ventricle in angiotensin II-induced hypertension. ( Anttinen, H; Hassinen, IE; Kainulainen, H; Leipälä, JA; Myllylä, R; Ruskoaho, H; Takala, TE; Vihko, V, 1988) |
| "Hexarelin treatment significantly reduced cardiac fibrosis in SHRs by decreasing interstitial and perivascular myocardial collagen deposition and myocardial hydroxyproline content and reducing mRNA and protein expression of collagen I and III in SHR hearts." | 5.38 | Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. ( Cao, JM; Chen, C; Ding, F; Gao, X; Hao, W; Pang, J; Xu, RK; Xu, X, 2012) |
| "Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy." | 5.35 | Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008) |
| "Colchicine has been demonstrated to suppress the release of fibroblast growth factors, retard collagen formation and augment collagenase activity." | 5.30 | Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat. ( Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Hayes, JA; Robinson, KG; Sen, S, 1997) |
| " Fourth, hydroxyproline concentration decreased in the left ventricle and hypertension was normalised." | 3.88 | Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model. ( Chicco, A; Creus, A; Ferreira, MR; Lombardo, YB; Oliva, ME, 2018) |
| "The present study aims to study the role of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin (RANKL/RANK/OPG) system in cardiac hypertrophy in a spontaneous hypertension rat (SHR) model and the effects of amlodipine and atorvastatin intervention." | 3.83 | Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. ( Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X, 2016) |
| "Zofenopril partially prevented the increase in systolic blood pressure and cardiac hypertrophy induced by angiotensin II and avoided the increase in collagen deposition." | 3.83 | Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition. ( Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA, 2016) |
| " We investigated whether compound 21 alone or in combination with angiotensin II type 1 receptor blockade by olmesartan medoxomil could prevent PWV increase and aortic remodeling in N(ω)-nitro-L-arginine-methyl ester (L-NAME)-induced hypertension." | 3.78 | Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling. ( Baulmann, J; Becker, ST; Dahlöf, B; Kaschina, E; Lucht, K; Paulis, L; Schwengel, K; Slavic, S; Steckelings, UM; Thöne-Reineke, C; Unger, T, 2012) |
| "The present study was designed to determine whether atorvastatin reduced hypertension-induced cardiac remodeling and whether these effects involved Protein Kinase D (PKD) and Myocyte Enhancer Factor 2D (MEF2D), factors known to be implicated in cardiac hypertrophy and fibrosis." | 3.76 | Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats. ( Geng, J; Kang, W; Wang, W; Zhang, Y; Zhao, Z; Zhiming, GE, 2010) |
| " LVH was characterized by increases in the ratios of heart and left ventricular weights to body weight, increased myocyte cross-sectional areas, myocardial and perivascular fibrosis, and elevated cardiac hydroxyproline." | 3.75 | K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function. ( Gao, S; Long, CL; Wang, H; Wang, RH, 2009) |
| "We investigated whether the substrate for nitric oxide synthesis L-arginine is able to modify hypertension and left ventricular hypertrophy development induced by chronic blockade of nitric oxide synthase activity by NG-nitro-L-arginine-methyl ester (L-NAME)." | 3.73 | L-arginine fails to protect against myocardial remodelling in L-NAME-induced hypertension. ( Babal, P; Bernatova, I; Gvozdjakova, A; Krajcirovicova, K; Kucharska, J; Luptak, I; Matuskova, J; Pechanova, O; Simko, F; Simko, J; Sumbalova, Z, 2005) |
| "Both enalapril and felodipine ameliorated adverse cardiovascular effects of hypertension in the aged SHRs within 12 weeks, as demonstrated by reduced arterial pressure, diminished left ventricular mass, and improved coronary hemodynamics." | 3.70 | Pharmacologic agents on cardiovascular mass, coronary dynamics and collagen in aged spontaneously hypertensive rats. ( Frohlich, ED; Susic, D; Varagic, J, 1999) |
| " Therefore, to evaluate the potential benefit of the angiotensin converting enzyme (ACE) inhibitor quinapril in reversing the interstitial remodeling in spontaneously hypertensive rats (SHR) with established left ventricular hypertrophy (LVH), we treated 16-week-old male SHR with oral quinapril (average dose, 10 mg/kg body weight/day) for 20 weeks." | 3.69 | Quinapril decreases myocardial accumulation of extracellular matrix components in spontaneously hypertensive rats. ( Cenarruzabeitia, E; Díez, J; Galindo, MF; Hernández, M; Panizo, A; Pardo, J, 1995) |
| "11 inhibitor that slows down the degradation of the cardiac hormone atrial natriuretic factor, producing a lowering of blood pressure in the DOCA-salt rat model of hypertension." | 3.68 | Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor. ( Bayburt, EK; Berry, CJ; Bohacek, RS; Capparelli, MP; Clarke, FH; Ghai, RD; MacPherson, LJ; Peppard, JV; Sakane, Y; Trapani, AJ, 1993) |
| "To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 3.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
| " Therapy with captopril, an angiotensin-converting enzyme inhibitor that regresses cardiac hypertrophy, not only reduces the total amount of collagen but reverses the altered distribution of type I and type III collagen." | 3.68 | Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats. ( Mukherjee, D; Sen, S, 1990) |
| " Percent hydroxyproline of intima-media segments of the thoracic aorta remained normal during the 8-week period, indicating that increases in aortic dry weight did not represent disproportional fibrosis and thus are attributable to muscular hypertrophy." | 3.67 | Aortic hypertrophy and "waterlogging" in the development of coarctation hypertension. ( Magargal, WW; Overbeck, HW, 1989) |
| "The effect of angiotensin II-induced hypertension on selected biochemical parameters was studied in Sprague-Dawley rats." | 3.67 | Transmural distribution of biochemical markers of total protein and collagen synthesis, myocardial contraction speed and capillary density in the rat left ventricle in angiotensin II-induced hypertension. ( Anttinen, H; Hassinen, IE; Kainulainen, H; Leipälä, JA; Myllylä, R; Ruskoaho, H; Takala, TE; Vihko, V, 1988) |
| "The effects of long-term treatment with verapamil on blood pressure, cardiac hypertrophy and collagen content, collagen concentration and prolyl hydroxylase activity were studied in spontaneously hypertensive rats (SHR)." | 3.67 | Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats. ( Ruskoaho, HJ; Savolainen, ER, 1985) |
| " Cardiomegaly has been produced in rats by sideropenic anaemia, by isoprenaline or thyroxine or by the application of both drugs, by artificial increase in resistance to blood flow and by long-term adaptation to hypoxia and physical stress." | 3.65 | The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly. ( Bartosová, D; Chvapil, M; Korecký, B; Poupa, O; Rakusan, K; Turek, Z; Vízek, M, 1969) |
| "Hexarelin treatment significantly reduced cardiac fibrosis in SHRs by decreasing interstitial and perivascular myocardial collagen deposition and myocardial hydroxyproline content and reducing mRNA and protein expression of collagen I and III in SHR hearts." | 1.38 | Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. ( Cao, JM; Chen, C; Ding, F; Gao, X; Hao, W; Pang, J; Xu, RK; Xu, X, 2012) |
| "Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy." | 1.35 | Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008) |
| "Pressure-overload left ventricular hypertrophy (LVH) is characterized by an increase in myocyte size and fibrosis." | 1.32 | Reduction of cardiac fibrosis decreases systolic performance without affecting diastolic function in hypertensive rats. ( Carretero, OA; Cingolani, OH; Liu, YH; Rhaleb, NE; Villanueva, M; Yang, XP, 2004) |
| "Colchicine has been demonstrated to suppress the release of fibroblast growth factors, retard collagen formation and augment collagenase activity." | 1.30 | Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat. ( Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Hayes, JA; Robinson, KG; Sen, S, 1997) |
| "In hypertensive cardiac hypertrophy, myosin heavy chain isoform shift and reduction of SR protein levels are related to systolic and diastolic dysfunction, respectively." | 1.30 | Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy. ( Arnold, G; Böhm, M; Flesch, M; Hirth-Dietrich, C; Paul, M; Pinto, Y; Rosenkranz, S; Schiffer, F; Zolk, O, 1997) |
| "Thus, in pressure-overloaded cardiac hypertrophy with coronary hypertension, coronary reserve seems to be determined by medial hypertrophy independently of collagen deposition, but collagen deposition plays an important role in the reversal of vasodilator reserve after relief of the overload." | 1.28 | Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy. ( Isoyama, S; Ito, N; Satoh, K; Takishima, T, 1992) |
| "At this age, hypertension has already caused a significant increase in the ratio of the ventricular mass to body weight (mg/g) in hypertensive animals (SHR: 5." | 1.28 | [Changes in myocardial collagen in spontaneously hypertensive rats (SHR)]. ( Garbisa, S; Guardiano, M; Onisto, M; Pauletto, P; Pessina, AC; Santipolo, N; Spina, M, 1991) |
| "The hydroxyproline concentration was increased in all parts of the hypertrophied myocardium in spontaneously hypertensive rats." | 1.26 | Collagen content in different areas of normal and hypertrophied rat myocardium. ( Medugorac, I, 1980) |
| "Biochemical and physical parameters of cardiac hypertrophy accompanying hypertension were studied in water deprived versus non-deprived immature spontaneously hypertensive rats (SHR) and their normotensive progenitor strain, Wistar Kyoto (WKY)." | 1.26 | Reduced left ventricular hypertrophy following long-term water deprivation in the young spontaneously hypertensive rat. ( Brackett, DJ; Schaefer, CF; Tompkins, P; Wilson, MF, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (36.11) | 18.7374 |
| 1990's | 18 (25.00) | 18.2507 |
| 2000's | 15 (20.83) | 29.6817 |
| 2010's | 13 (18.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oliva, ME | 1 |
| Creus, A | 1 |
| Ferreira, MR | 1 |
| Chicco, A | 1 |
| Lombardo, YB | 1 |
| Chen, P | 1 |
| Qiao, D | 1 |
| Liu, X | 3 |
| Geng, J | 2 |
| Zhao, Z | 2 |
| Yang, L | 2 |
| Zhang, M | 1 |
| Du, CQ | 1 |
| Yang, J | 1 |
| Han, J | 1 |
| Hu, XS | 1 |
| Wu, T | 1 |
| Hu, SJ | 2 |
| Rosa, CM | 1 |
| Xavier, NP | 1 |
| Henrique Campos, D | 1 |
| Fernandes, AA | 1 |
| Cezar, MD | 1 |
| Martinez, PF | 1 |
| Cicogna, AC | 2 |
| Gimenes, C | 1 |
| Gimenes, R | 1 |
| Okoshi, MP | 1 |
| Okoshi, K | 1 |
| Huang, LL | 1 |
| Pan, C | 1 |
| Wang, L | 1 |
| Ding, L | 1 |
| Guo, K | 1 |
| Wang, HZ | 1 |
| Xu, AM | 1 |
| Gao, S | 2 |
| Zhang, G | 1 |
| Yang, G | 1 |
| Deng, Y | 1 |
| Zhao, X | 2 |
| Yang, Y | 1 |
| Rao, J | 1 |
| Wang, W | 2 |
| He, J | 1 |
| Lv, L | 1 |
| Lu, J | 1 |
| Liu, F | 1 |
| Liu, D | 1 |
| Du, H | 1 |
| Hao, J | 1 |
| Yang, X | 1 |
| Cui, W | 1 |
| Gómez-Roso, M | 1 |
| Montero, MJ | 1 |
| Carrón, R | 1 |
| Sevilla, MA | 1 |
| Cavallari, LH | 1 |
| Fashingbauer, LA | 1 |
| Camp, JR | 1 |
| King, ST | 1 |
| Geenen, DL | 1 |
| Zhang, LK | 1 |
| Zhang, CY | 1 |
| Zeng, XJ | 1 |
| Yan, H | 1 |
| Jin, HF | 1 |
| Tang, CS | 1 |
| DU, JB | 1 |
| Long, CL | 1 |
| Wang, RH | 1 |
| Wang, H | 1 |
| Olempieva, EV | 1 |
| Mikashinovich, ZI | 1 |
| Shlyk, SV | 1 |
| Loginov, IA | 1 |
| Kang, W | 1 |
| Zhang, Y | 1 |
| Zhiming, GE | 1 |
| Paulis, L | 1 |
| Becker, ST | 1 |
| Lucht, K | 1 |
| Schwengel, K | 1 |
| Slavic, S | 1 |
| Kaschina, E | 1 |
| Thöne-Reineke, C | 1 |
| Dahlöf, B | 1 |
| Baulmann, J | 1 |
| Unger, T | 1 |
| Steckelings, UM | 1 |
| Xu, X | 1 |
| Ding, F | 1 |
| Pang, J | 1 |
| Gao, X | 1 |
| Xu, RK | 1 |
| Hao, W | 1 |
| Cao, JM | 1 |
| Chen, C | 1 |
| Wang, Y | 1 |
| Wang, DH | 1 |
| Joseph, J | 1 |
| Washington, A | 1 |
| Joseph, L | 1 |
| Koehler, L | 1 |
| Fink, LM | 1 |
| Hauer-Jensen, M | 1 |
| Kennedy, RH | 1 |
| Baccarani Contri, M | 1 |
| Taparelli, F | 1 |
| Miselli, M | 1 |
| Bacchelli, B | 1 |
| Biagini, G | 1 |
| NAKASHIMA, T | 1 |
| IWANAGA, Y | 1 |
| NAKAURA, Y | 1 |
| LAGIER, R | 1 |
| RUTISHAUSER, E | 1 |
| Cingolani, OH | 1 |
| Yang, XP | 1 |
| Liu, YH | 1 |
| Villanueva, M | 1 |
| Rhaleb, NE | 1 |
| Carretero, OA | 1 |
| Ahn, J | 1 |
| Varagic, J | 4 |
| Slama, M | 1 |
| Susic, D | 4 |
| Frohlich, ED | 5 |
| Polivoda, SN | 1 |
| Cherepok, AA | 1 |
| Sychev, RA | 1 |
| Simko, F | 1 |
| Luptak, I | 1 |
| Matuskova, J | 1 |
| Krajcirovicova, K | 1 |
| Sumbalova, Z | 1 |
| Kucharska, J | 1 |
| Gvozdjakova, A | 1 |
| Simko, J | 1 |
| Babal, P | 2 |
| Pechanova, O | 2 |
| Bernatova, I | 2 |
| Kang, L | 1 |
| Fukumoto, M | 1 |
| Himeno, N | 1 |
| Asai, M | 1 |
| Midorikawa, O | 1 |
| Tompkins, P | 1 |
| Wilson, MF | 1 |
| Brackett, DJ | 1 |
| Schaefer, CF | 1 |
| Medugorac, I | 2 |
| Kunz, J | 1 |
| Braselmann, H | 1 |
| Gottschalk, J | 1 |
| Kreher, C | 1 |
| Pieper, KS | 1 |
| Busacca, M | 1 |
| Luerti, M | 1 |
| Tonta, A | 1 |
| Díez, J | 2 |
| Laviades, C | 1 |
| Monreal, I | 1 |
| Gil, MJ | 1 |
| Panizo, A | 2 |
| Pardo, J | 2 |
| Hernández, M | 1 |
| Galindo, MF | 1 |
| Cenarruzabeitia, E | 1 |
| Conrad, CH | 2 |
| Brooks, WW | 2 |
| Hayes, JA | 2 |
| Sen, S | 5 |
| Robinson, KG | 2 |
| Bing, OH | 2 |
| Besse, S | 1 |
| Robert, V | 1 |
| Assayag, P | 1 |
| Delcayre, C | 1 |
| Swynghedauw, B | 1 |
| Why, HJ | 1 |
| Patel, VB | 1 |
| Richardson, PJ | 1 |
| Preedy, VR | 1 |
| MacPherson, LJ | 1 |
| Bayburt, EK | 1 |
| Capparelli, MP | 1 |
| Bohacek, RS | 1 |
| Clarke, FH | 1 |
| Ghai, RD | 1 |
| Sakane, Y | 1 |
| Berry, CJ | 1 |
| Peppard, JV | 1 |
| Trapani, AJ | 1 |
| Atlante, A | 1 |
| Seccia, TM | 1 |
| Marra, E | 1 |
| Minervini, GM | 1 |
| Vulpis, V | 1 |
| Pirrelli, A | 1 |
| Passarella, S | 1 |
| Flesch, M | 1 |
| Schiffer, F | 1 |
| Zolk, O | 1 |
| Pinto, Y | 1 |
| Rosenkranz, S | 1 |
| Hirth-Dietrich, C | 1 |
| Arnold, G | 1 |
| Paul, M | 1 |
| Böhm, M | 1 |
| Nunez, E | 1 |
| Hosoya, K | 1 |
| Pelouch, V | 1 |
| van Gorp, AW | 1 |
| Schenau, DS | 1 |
| Hoeks, AP | 1 |
| Boudier, HA | 1 |
| de Mey, JG | 1 |
| Reneman, RS | 1 |
| Yamamoto, K | 1 |
| Masuyama, T | 1 |
| Sakata, Y | 1 |
| Nishikawa, N | 1 |
| Mano, T | 1 |
| Yoshida, J | 1 |
| Miwa, T | 1 |
| Sugawara, M | 1 |
| Yamaguchi, Y | 1 |
| Ookawara, T | 1 |
| Suzuki, K | 1 |
| Hori, M | 1 |
| Tarazi, RC | 2 |
| Bumpus, FM | 2 |
| Newman, RA | 1 |
| Langner, RO | 1 |
| Eroshevskiĭ, TI | 1 |
| Sviatkovskaia, TIa | 1 |
| Isoyama, S | 1 |
| Ito, N | 1 |
| Satoh, K | 1 |
| Takishima, T | 1 |
| Poiani, GJ | 1 |
| Wilson, FJ | 1 |
| Fox, JD | 1 |
| Sumka, JM | 1 |
| Peng, BW | 1 |
| Liao, WC | 1 |
| Tozzi, CA | 1 |
| Riley, DJ | 1 |
| Grover-McKay, M | 1 |
| Scholz, TD | 1 |
| Burns, TL | 1 |
| Skorton, DJ | 1 |
| Takemori, E | 1 |
| Hasegawa, Y | 1 |
| Katahira, J | 1 |
| Nakao, K | 1 |
| Inukai, T | 1 |
| Santipolo, N | 1 |
| Guardiano, M | 1 |
| Pessina, AC | 1 |
| Pauletto, P | 1 |
| Onisto, M | 1 |
| Garbisa, S | 1 |
| Spina, M | 1 |
| Mukherjee, D | 1 |
| Motz, W | 1 |
| Strauer, BE | 1 |
| Overbeck, HW | 1 |
| Magargal, WW | 1 |
| Falcy, C | 1 |
| Farjanel, J | 1 |
| Rattner, A | 1 |
| Grochulski, A | 1 |
| Gilson, N | 1 |
| Borsos, AM | 1 |
| Christeff, N | 1 |
| Dupeyron, JP | 1 |
| Peyroux, J | 1 |
| Sternberg, M | 1 |
| Leipälä, JA | 1 |
| Takala, TE | 1 |
| Ruskoaho, H | 1 |
| Myllylä, R | 1 |
| Kainulainen, H | 1 |
| Hassinen, IE | 1 |
| Anttinen, H | 1 |
| Vihko, V | 1 |
| Ruskoaho, HJ | 1 |
| Savolainen, ER | 1 |
| Molteni, A | 1 |
| Ward, WF | 1 |
| Ts'ao, CH | 1 |
| Solliday, NH | 1 |
| Hammerman, H | 1 |
| Kloner, RA | 1 |
| Alker, KJ | 1 |
| Schoen, FJ | 1 |
| Braunwald, E | 1 |
| Hausmann, J | 1 |
| Jelínek, J | 1 |
| Deyl, Z | 1 |
| Bartosová, D | 1 |
| Chvapil, M | 1 |
| Korecký, B | 1 |
| Poupa, O | 1 |
| Rakusan, K | 1 |
| Turek, Z | 1 |
| Vízek, M | 1 |
| Alinder, I | 1 |
| Boström, H | 1 |
| Robert, L | 1 |
| Kadar, A | 1 |
| Robert, B | 1 |
| Kubel, M | 1 |
| Jacotot, B | 1 |
| Rambaud, J | 1 |
| Denis, JC | 1 |
| Cahn, J | 1 |
| Buxtorf, JC | 1 |
| Patois, E | 1 |
| Beaumont, JL | 1 |
| Lopatyński, J | 1 |
3 reviews available for hydroxyproline and Blood Pressure, High
| Article | Year |
|---|---|
Sodium directly impairs target organ function in hypertension.
Topics: Animals; Blood Pressure; Heart; Hydroxyproline; Hypertension; Kidney; Myocardium; Rats; Rats, Inbred | 2005 |
Toward the biochemical assessment of myocardial fibrosis in hypertensive patients.
Topics: Animals; Arrhythmias, Cardiac; Biochemical Phenomena; Biochemistry; Biomarkers; Endomyocardial Fibro | 1995 |
The macromolecules of the intercellular matrix of the arterial wall: collagen, elastin, proteoglycans, and glycoproteins.
Topics: Age Factors; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Radioisotopes; Chickens; Coll | 1974 |
69 other studies available for hydroxyproline and Blood Pressure, High
| Article | Year |
|---|---|
Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model.
Topics: Animals; Carnitine O-Palmitoyltransferase; Dietary Proteins; Dietary Sucrose; Disease Models, Animal | 2018 |
Effects and Mechanism of SO2 Inhalation on Rat Myocardial Collagen Fibers.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weights and Measures; Collagen; Heart; Heart Ventricle | 2018 |
Protein Kinase D was involved in vascular remodeling in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Hydroxyproline; Hypertension; Interleukin-6; Male; Protein Kinase C; | 2019 |
Inhibition of farnesyl pyrophosphate synthase prevents norepinephrine-induced fibrotic responses in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Proliferation; Cells, Cultured; Dimethylallyltranstran | 2014 |
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Cardiac Myosins; Diabetes Mellitus, Experimental; Diabetic Cardi | 2013 |
Protective effects of grape seed proanthocyanidins on cardiovascular remodeling in DOCA-salt hypertension rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Desoxycorticosterone Acetate; Endothelin-1; Grape Se | 2015 |
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Topics: Animals; Blood Pressure; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Endomyocardial Fib | 2016 |
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats.
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Cros | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, T | 2016 |
Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Collagen Type I; Fibrosis; Gene Expression Regula | 2008 |
Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Division; Collagen Type I; Hydrogen S | 2008 |
K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function.
Topics: Animals; Aorta, Abdominal; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Agents; Disease | 2009 |
[Metabolic changes in blood of reproductive age women with hypertensive disease].
Topics: Adult; Age Factors; Biomarkers; Female; Humans; Hydroxyproline; Hypertension; Kallikreins; Malondial | 2009 |
Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats.
Topics: Animals; Atorvastatin; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoi | 2010 |
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Body W | 2012 |
Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiovascular Agents; Collagen Type I; Collagen Type III; Disease Models, | 2012 |
Role of substance P in renal injury during DOCA-salt hypertension.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Hydroxyproline; Hypertension; Isoindoles; Kidney; Mal | 2012 |
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats.
Topics: Animals; Arterioles; Collagen; Coronary Vessels; Diastole; Disease Models, Animal; Food, Formulated; | 2002 |
Histomorphometric, biochemical and ultrastructural changes in the aorta of salt-loaded stroke-prone spontaneously hypertensive rats fed a Japanese-style diet.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Collagen; Desmosine; Diet; Elastin; Endothelium, Va | 2003 |
PATHOLOGIC STUDY OF HYPERTENSIVE HEART.
Topics: Adolescent; Amino Acids; Body Weight; Cardiomegaly; Child; Collagen; Coronary Disease; Geriatrics; H | 1964 |
OSTEOARTICULAR CHANGES IN A CASE OF ESSENTIAL OSTEOLYSIS; AN ANATOMICAL AND RADIOLOGICAL STUDY.
Topics: Adolescent; Blood; Bone Diseases; Bone Resorption; Cartilage Diseases; Elbow; Foot; Hand; Humans; Hy | 1965 |
Reduction of cardiac fibrosis decreases systolic performance without affecting diastolic function in hypertensive rats.
Topics: Animals; Capillaries; Cell Size; Collagen; Diastole; Fibrosis; Heart Ventricles; Hydroxyproline; Hyp | 2004 |
Cardiac structural and functional responses to salt loading in SHR.
Topics: Aging; Animals; Blood Pressure; Cardiomegaly; Echocardiography; Fibrosis; Heart; Heart Failure; Hydr | 2004 |
[Structural and functional reconfiguration of large arteries in hypertensive disease: a role of connective tissue metabolic disturbances].
Topics: Adult; Aged; Aorta; Blood Flow Velocity; Connective Tissue; Elasticity; Elastin; Female; Glycosamino | 2004 |
L-arginine fails to protect against myocardial remodelling in L-NAME-induced hypertension.
Topics: Animals; Antihypertensive Agents; Arginine; Brain; Hydroxyproline; Hypertension; Hypertrophy, Left V | 2005 |
[Effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats].
Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Blood Pressure; Heptanoic Acids; Hydroxy | 2007 |
Effects of prolyl hydroxylase inhibition on arterial collagen synthesis and blood pressure in hypertensive rats.
Topics: Animals; Anthraquinones; Arteries; Blood Pressure; Collagen; Desoxycorticosterone; Hydroxyproline; H | 1984 |
Reduced left ventricular hypertrophy following long-term water deprivation in the young spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; DNA; Female; Hydroxyproline; Hypertension; Male; Myocardium; | 1980 |
Myocardial collagen in different forms of heart hypertrophy in the rat.
Topics: Animals; Aortic Valve Stenosis; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertension, | 1980 |
Collagen content in different areas of normal and hypertrophied rat myocardium.
Topics: Animals; Cardiomegaly; Collagen; Heart Ventricles; Hydroxyproline; Hypertension; Myocardium; Rats | 1980 |
The myocardial collagenous connective tissue in experimental cardiac hypertrophy induced by swimming exercise and hypertension.
Topics: Animals; Autoradiography; Cardiomegaly; Collagen; Connective Tissue; Hydroxyproline; Hypertension; M | 1981 |
[Total hydroxyproline in the amniotic fluid. Its clinical importance].
Topics: Adult; Amniotic Fluid; Female; Fetal Growth Retardation; Humans; Hydroxyproline; Hypertension; Pregn | 1981 |
Quinapril decreases myocardial accumulation of extracellular matrix components in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Collagen | 1995 |
Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat.
Topics: Aging; Animals; Cardiomegaly; Endomyocardial Fibrosis; Heart Failure; Hydroxyproline; Hypertension; | 1995 |
Nonsynchronous changes in myocardial collagen mRNA and protein during aging: effect of DOCA-salt hypertension.
Topics: Aging; Animals; Collagen; Desoxycorticosterone; Heart Ventricles; Hydroxyproline; Hypertension; Myoc | 1994 |
Effects of angiotensin converting enzyme inhibition on cardiac collagen in hypertensive and normotensive rats.
Topics: Amlodipine; Animals; Blood Pressure; Collagen; Heart; Hydroxyproline; Hypertension; Lisinopril; Male | 1994 |
Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.
Topics: Administration, Oral; Amino Acid Sequence; Animals; Antihypertensive Agents; Atrial Natriuretic Fact | 1993 |
Carrier-mediated transport controls hydroxyproline catabolism in heart mitochondria from spontaneously hypertensive rat.
Topics: Animals; Biological Transport; Heart Ventricles; Hydroxyproline; Hypertension; Intracellular Membran | 1996 |
Effect of chronic colchicine administration on the myocardium of the aging spontaneously hypertensive rat.
Topics: Aging; Animals; Colchicine; Disease Models, Animal; Fibrosis; Heart; Hydroxyproline; Hypertension; M | 1997 |
Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium-Binding Proteins; Calcium-Transporti | 1997 |
Coronary hemodynamics in aging spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Aging; Animals; Aorta; Body Weight; Collagen; Coronary Circulation; Fibrosis; Hemodynamics; Hydroxyp | 1998 |
Pharmacologic agents on cardiovascular mass, coronary dynamics and collagen in aged spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Calc | 1999 |
L-NAME-induced protein remodeling and fibrosis in the rat heart.
Topics: Animals; Blood Pressure; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endomyocardial Fibr | 1999 |
In spontaneously hypertensive rats alterations in aortic wall properties precede development of hypertension.
Topics: Adrenergic alpha-Agonists; Age Factors; Anesthetics, Dissociative; Animals; Aorta, Thoracic; Blood P | 2000 |
Coronary hemodynamic and ventricular responses to angiotensin type 1 receptor inhibition in SHR: interaction with angiotensin type 2 receptors.
Topics: Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure | 2001 |
Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; | 2002 |
Biochemical changes associated with development and reversal of cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Methyldopa; Myocardium; Myosins; Organ Siz | 1976 |
Cardiac hypertrophy and antihypertensive therapy.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Male; Methyldopa; Minoxidil; Myocardium; P | 1977 |
Age-related changes in the vascular collagen metabolism of the spontaneously hypertensive rat.
Topics: Aging; Animals; Aorta; Blood Vessels; Collagen; DNA; Hydroxyproline; Hypertension; In Vitro Techniqu | 1978 |
[Collagen metabolism in primary glaucoma].
Topics: Adult; Aged; Arteriosclerosis; Collagen; Glaucoma; Humans; Hydroxyproline; Hypertension; Intraocular | 1979 |
Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy.
Topics: Aminopropionitrile; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Body Weight; Carbon Diox | 1992 |
Liposome-entrapped antifibrotic agent prevents collagen accumulation in hypertensive pulmonary arteries of rats.
Topics: Animals; Collagen; Drug Carriers; Fibrosis; Hydroxyproline; Hypertension; Liposomes; Male; Microscop | 1992 |
Myocardial collagen concentration and nuclear magnetic resonance relaxation times in the spontaneously hypertensive rat.
Topics: Aging; Animals; Body Water; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Magnetic Resonance | 1991 |
Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biomarkers; Blood Pres | 1991 |
[Changes in myocardial collagen in spontaneously hypertensive rats (SHR)].
Topics: Age Factors; Animals; Cardiomegaly; Collagen; Densitometry; Elasticity; Electrophoresis; Hydroxyprol | 1991 |
Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Animals; Captopril; Cardiomegaly; Collagen; Cyanogen Bromide; Female; Hydroxyproline; H | 1990 |
Left ventricular function and collagen content after regression of hypertensive hypertrophy.
Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Hypertension; Nifedipine; Rats; Rats, Inbred | 1989 |
Aortic hypertrophy and "waterlogging" in the development of coarctation hypertension.
Topics: Amino Acids; Animals; Aorta; Aortic Coarctation; Blood Pressure; Body Water; Fibrosis; Hydroxyprolin | 1989 |
Aorta collagen metabolism in spontaneously hypertensive and aortic-constricted rats: variations in enzyme activities concerned with disaccharide unit synthesis and degradation according to blood pressure and age.
Topics: Age Factors; alpha-Glucosidases; Animals; Aorta, Thoracic; Blood Pressure; Collagen; Constriction, P | 1985 |
Transmural distribution of biochemical markers of total protein and collagen synthesis, myocardial contraction speed and capillary density in the rat left ventricle in angiotensin II-induced hypertension.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Biomarkers; Capillaries; Collagen; Heart Ventricles; | 1988 |
Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Female; Heart; Hydroxyproline; Hypertension; | 1985 |
Monocrotaline-induced cardiopulmonary damage in rats: amelioration by the angiotensin-converting enzyme inhibitor CL242817.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Occlusive Diseases; Body Weight; Heart; | 1986 |
Effects of transient increased afterload during experimentally induced acute myocardial infarction in dogs.
Topics: Animals; Dogs; Heart Ventricles; Hydroxyproline; Hypertension; Methoxamine; Myocardial Infarction; R | 1985 |
Changes in glomerular basement membrane collagen caused by DOCA-NaCl treatment in rats.
Topics: Animals; Basement Membrane; Collagen; Desoxycorticosterone; Hydroxyproline; Hypertension; Kidney Glo | 1985 |
The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly.
Topics: Anemia, Hypochromic; Animals; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertrophy; Hyp | 1969 |
Clinical studies on a Swedish material of pseudoxanthoma elasticum.
Topics: Adolescent; Adult; Aged; Angina Pectoris; Angioid Streaks; Cardiomegaly; Child; Child, Preschool; El | 1972 |
[Hydroxyproline content of the myocardium in patients with hypertrophy of the left heart and severe arteriosclerosis].
Topics: Adult; Aged; Arteriosclerosis; Autopsy; Cardiomyopathies; Collagen; Diabetes Mellitus; Female; Heart | 1974 |
[Prevention of certain acute and chronic effects of nicotine by N-acetylhydroxyproline].
Topics: Animals; Cerebral Cortex; Electroencephalography; Female; Humans; Hydroxyproline; Hypertension; Male | 1971 |
[Studies on the chemical composition of vascular walls. IX. Effect of experimentally induced arterial hypertension and atherogenic diet on certain protein fractions of the aortic wall].
Topics: Animals; Aorta; Diet, Atherogenic; Hydroxyproline; Hypertension; Nitrogen; Proline; Rats | 1968 |