hydroxyproline has been researched along with Asthma in 31 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to compare fluticasone propionate (FP) with budesonide (BUD) at a dose of 400 microg x day(-1) in the treatment of children with asthma." | 9.08 | Fluticasone propionate compared with budesonide: a double-blind trial in asthmatic children using powder devices at a dosage of 400 microg x day(-1). ( Efthimiou, J; Hedlin, G; Hoekx, JC; Hollingworth, K; Pedersen, W; Sorva, R, 1996) |
| " We compared the safety and efficacy of fluticasone propionate (FP) and beclomethasone dipropionate (BDP) in 306 patients with moderate to severe asthma in a double-blind, multicenter, cross-over study of 12 mo duration." | 9.08 | Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma. Belgian Multicenter Study Group. ( Demedts, MG; Geusens, P; Pauwels, RA; Yernault, JC, 1998) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 7.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 7.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " Imiquimod, a synthetic Toll-like receptor (TLR) 7 ligand, has been shown to attenuate airway inflammation and airway hyperresponsiveness (AHR) in acute murine models of allergic asthma." | 7.75 | Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma. ( Chen, Z; Du, Q; Gu, XY; Huang, M; Yin, KS; Zhou, LF, 2009) |
| "Hypercalcemia and hypercalciuria observed both in humans and in animals who were on long-term theophylline therapy, prompted us to investigate whether oral theophylline treatment at optimal doses causes any adverse side effects on bone metabolism in mild asthmatics." | 7.70 | Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics. ( Büyüköztürk, S; Gürdöl, F; Kolanci, C; Oner, P; Oner-Iyidon, Y, 1999) |
| "The aim of this study was to compare fluticasone propionate (FP) with budesonide (BUD) at a dose of 400 microg x day(-1) in the treatment of children with asthma." | 5.08 | Fluticasone propionate compared with budesonide: a double-blind trial in asthmatic children using powder devices at a dosage of 400 microg x day(-1). ( Efthimiou, J; Hedlin, G; Hoekx, JC; Hollingworth, K; Pedersen, W; Sorva, R, 1996) |
| " We compared the safety and efficacy of fluticasone propionate (FP) and beclomethasone dipropionate (BDP) in 306 patients with moderate to severe asthma in a double-blind, multicenter, cross-over study of 12 mo duration." | 5.08 | Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma. Belgian Multicenter Study Group. ( Demedts, MG; Geusens, P; Pauwels, RA; Yernault, JC, 1998) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 3.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| "The authors developed a mouse model of chronic asthma in which ovalbumin (OVA)-sensitized female BALB/c-mice were exposed to intranasal OVA administration twice a week for 3 months." | 3.76 | Inhibitory effects of anti-immunoglobulin E antibodies on airway remodeling in a murine model of chronic asthma. ( Kang, JY; Kim, JS; Kim, JW; Kim, SJ; Kim, YK; Kwon, SS; Lee, SH; Lee, SY; Moon, HS; Park, SH; Song, JS, 2010) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 3.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " Imiquimod, a synthetic Toll-like receptor (TLR) 7 ligand, has been shown to attenuate airway inflammation and airway hyperresponsiveness (AHR) in acute murine models of allergic asthma." | 3.75 | Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma. ( Chen, Z; Du, Q; Gu, XY; Huang, M; Yin, KS; Zhou, LF, 2009) |
| " To test the hypothesis that the absence of TIMP-1 enhances allergic lung inflammation, airway hyperreactivity (AHR), and lung remodeling in asthma, we studied TIMP-1 null (TIMP-1 KO) mice and their WT controls using an ovalbumin (OVA) asthma model." | 3.75 | Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma. ( Aalinkeel, R; Blume, JW; Fang, YV; Knight, PR; Lachina, S; Mahajan, SD; Mullan, BA; Ohtake, PJ; Sands, MF; Schwartz, SA; Sykes, DE; Takyar, SS, 2009) |
| "The role of procoagulant factor X in a murine model of ovalbumin (OVA)-induced asthma was investigated." | 3.74 | Coagulation factor Xa modulates airway remodeling in a murine model of asthma. ( Castellino, FJ; Martin, JA; Ploplis, VA; Shinagawa, K, 2007) |
| "Hypercalcemia and hypercalciuria observed both in humans and in animals who were on long-term theophylline therapy, prompted us to investigate whether oral theophylline treatment at optimal doses causes any adverse side effects on bone metabolism in mild asthmatics." | 3.70 | Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics. ( Büyüköztürk, S; Gürdöl, F; Kolanci, C; Oner, P; Oner-Iyidon, Y, 1999) |
| "Asthma is an inflammatory disease of airways, and the main trigger of asthma is allergic inflammation." | 1.72 | Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects. ( Athari, SS; Li, M; Li, Y; Wang, B; Wang, J; Wang, R, 2022) |
| "We developed a mouse model of airway remodeling, which includes smooth muscle thickening, in which ovalbumin (OVA)-sensitized mice were repeatedly exposed to intranasal OVA administration twice a week for 3 months." | 1.40 | Effect of nilotinib on airway remodeling in a murine model of chronic asthma. ( Kang, JY; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2014) |
| "Ovalbumin (OVA) was administered intraperitoneally to BALB/c mice on days 0 and 14, and the mice were then exposed to aerosolized OVA daily for 4 weeks." | 1.35 | Effects of KF19514, a phosphodiesterase 4 and 1 Inhibitor, on bronchial inflammation and remodeling in a murine model of chronic asthma. ( Fujimura, M; Kita, T; Myou, S; Nakao, S; Waseda, Y; Watanabe, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (19.35) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 8 (25.81) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Li, M | 1 |
| Wang, R | 1 |
| Wang, B | 1 |
| Athari, SS | 1 |
| Wang, J | 1 |
| Xu, BM | 1 |
| Zhang, JH | 1 |
| Wang, JL | 1 |
| Xiao, JH | 1 |
| Rhee, CK | 2 |
| Kang, JY | 2 |
| Park, CK | 2 |
| Lee, SY | 3 |
| Kwon, SS | 3 |
| Kim, YK | 3 |
| Yoon, HK | 2 |
| Zhou, DY | 1 |
| Fang, SR | 1 |
| Zou, CF | 1 |
| Zhang, Q | 2 |
| Gu, W | 1 |
| Kim, SW | 1 |
| Kim, JH | 1 |
| Kim, TJ | 1 |
| Du, Q | 2 |
| Chen, Z | 2 |
| Zhou, LF | 2 |
| Huang, M | 2 |
| Yin, KS | 2 |
| Gu, XY | 1 |
| Sands, MF | 1 |
| Ohtake, PJ | 1 |
| Mahajan, SD | 1 |
| Takyar, SS | 1 |
| Aalinkeel, R | 1 |
| Fang, YV | 1 |
| Blume, JW | 1 |
| Mullan, BA | 1 |
| Sykes, DE | 1 |
| Lachina, S | 1 |
| Knight, PR | 1 |
| Schwartz, SA | 1 |
| Kuramoto, E | 1 |
| Nishiuma, T | 1 |
| Kobayashi, K | 1 |
| Yamamoto, M | 1 |
| Kono, Y | 1 |
| Funada, Y | 1 |
| Kotani, Y | 1 |
| Sisson, TH | 1 |
| Simon, RH | 1 |
| Nishimura, Y | 1 |
| Kita, T | 1 |
| Fujimura, M | 1 |
| Myou, S | 1 |
| Watanabe, K | 1 |
| Waseda, Y | 1 |
| Nakao, S | 1 |
| Komai, M | 4 |
| Tanaka, H | 4 |
| Nagao, K | 4 |
| Ishizaki, M | 2 |
| Kajiwara, D | 2 |
| Miura, T | 1 |
| Ohashi, H | 1 |
| Haba, T | 1 |
| Kawakami, K | 1 |
| Sawa, E | 1 |
| Yoshie, O | 1 |
| Inagaki, N | 1 |
| Nagai, H | 4 |
| Kim, JW | 1 |
| Kim, JS | 1 |
| Kim, SJ | 1 |
| Lee, SH | 1 |
| Moon, HS | 1 |
| Song, JS | 1 |
| Park, SH | 1 |
| Bourke, JE | 1 |
| Li, X | 1 |
| Foster, SR | 1 |
| Wee, E | 1 |
| Dagher, H | 1 |
| Ziogas, J | 1 |
| Harris, T | 1 |
| Bonacci, JV | 1 |
| Stewart, AG | 1 |
| Zeki, AA | 1 |
| Bratt, JM | 1 |
| Rabowsky, M | 1 |
| Last, JA | 1 |
| Kenyon, NJ | 1 |
| Masuda, T | 2 |
| Narumiya, S | 1 |
| Corbel, M | 1 |
| Caulet-Maugendre, S | 1 |
| Germain, N | 1 |
| Lagente, V | 1 |
| Boichot, E | 1 |
| Takatsu, K | 1 |
| Delespesse, G | 1 |
| Berlin, AA | 1 |
| Hogaboam, CM | 1 |
| Lukacs, NW | 1 |
| Shinagawa, K | 1 |
| Martin, JA | 1 |
| Ploplis, VA | 1 |
| Castellino, FJ | 1 |
| Wolthers, OD | 1 |
| Riis, BJ | 1 |
| Pedersen, S | 1 |
| Hoekx, JC | 1 |
| Hedlin, G | 1 |
| Pedersen, W | 1 |
| Sorva, R | 1 |
| Hollingworth, K | 1 |
| Efthimiou, J | 1 |
| Pauwels, RA | 1 |
| Yernault, JC | 1 |
| Demedts, MG | 1 |
| Geusens, P | 1 |
| Haapasaari, K | 1 |
| Rossi, O | 1 |
| Risteli, J | 1 |
| Oikarinen, A | 1 |
| Oner, P | 1 |
| Gürdöl, F | 1 |
| Oner-Iyidon, Y | 1 |
| Kolanci, C | 1 |
| Büyüköztürk, S | 1 |
| Tokuoka, S | 1 |
| Takahashi, Y | 1 |
| Garmash, VIa | 1 |
| Iakushin, SS | 1 |
| Shifrin, MA | 1 |
| Ermak, IS | 1 |
| Kartoziia, TsI | 1 |
| Egnatashvili, TSh | 1 |
| Imedashvili, MV | 1 |
| Zhorzholiani, LD | 1 |
| Reid, IR | 1 |
| Gluckman, PD | 1 |
| Ibbertson, HK | 1 |
| Moulaert, AJ | 1 |
| Van Gemund, JJ | 1 |
| Gallagher, JC | 1 |
| Aaron, J | 1 |
| Horsman, A | 1 |
| Wilkinson, R | 1 |
| Nordin, BE | 1 |
| Matiasevic, D | 1 |
| Gershberg, H | 1 |
3 trials available for hydroxyproline and Asthma
| Article | Year |
|---|---|
Bone turnover in asthmatic children treated with oral prednisolone or inhaled budesonide.
Topics: 25-Hydroxyvitamin D 2; Administration, Inhalation; Administration, Oral; Adolescent; Alkaline Phosph | 1993 |
Fluticasone propionate compared with budesonide: a double-blind trial in asthmatic children using powder devices at a dosage of 400 microg x day(-1).
Topics: Administration, Topical; Adolescent; Aerosols; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammat | 1996 |
Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma. Belgian Multicenter Study Group.
Topics: Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Androstadiene | 1998 |
28 other studies available for hydroxyproline and Asthma
| Article | Year |
|---|---|
Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, | 2022 |
TRPC3 overexpression and intervention in airway smooth muscle of ovalbumin-induced hyperresponsiveness and remodeling.
Topics: Acetylcholine; Airway Remodeling; Aminophylline; Animals; Antibodies; Asthma; Calcium; Cell Prolifer | 2018 |
Effect of nilotinib on airway remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Chronic Disease; Disease Models, Animal; Female; Hydroxy | 2014 |
Proanthocyanidin from grape seed extract inhibits airway inflammation and remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Female; Grape Seed Extract | 2015 |
Effect of roflumilast on airway remodelling in a murine model of chronic asthma.
Topics: Airway Remodeling; Allergens; Aminopyridines; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Br | 2016 |
Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma.
Topics: Actins; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Ch | 2008 |
Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma.
Topics: Adaptation, Physiological; Adjuvants, Immunologic; Aminoquinolines; Animals; Asthma; Bronchoalveolar | 2009 |
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression; Hydroxyproline; Immunoglobulin | 2009 |
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Topics: Administration, Inhalation; Animals; Asthma; Base Sequence; Bronchoalveolar Lavage Fluid; Cells, Cul | 2009 |
Effects of KF19514, a phosphodiesterase 4 and 1 Inhibitor, on bronchial inflammation and remodeling in a murine model of chronic asthma.
Topics: Acetylcholine; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconst | 2009 |
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Respo | 2010 |
Inhibitory effects of anti-immunoglobulin E antibodies on airway remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Antibodies, Anti-Idiotypic; Asthma; Bronchial Provocation Tests; | 2010 |
Collagen remodelling by airway smooth muscle is resistant to steroids and β₂-agonists.
Topics: Adrenergic beta-Agonists; Asthma; Bronchi; Calcium; Cell Line; Cell Movement; Collagen; Drug Resista | 2011 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, A | 2010 |
Role of prostaglandin I2 in airway remodeling induced by repeated allergen challenge in mice.
Topics: Allergens; Alum Compounds; Animals; Antigens; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage | 2003 |
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Cytokines; Disease Model | 2003 |
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Topics: Actins; Allergens; Animals; Antibodies; Asthma; Bronchi; Chemotaxis, Leukocyte; Collagen; Disease Mo | 2004 |
Inhibition of SCF attenuates peribronchial remodeling in chronic cockroach allergen-induced asthma.
Topics: Administration, Intranasal; Allergens; Animals; Asthma; Benzamides; Bronchi; Bronchial Hyperreactivi | 2006 |
Coagulation factor Xa modulates airway remodeling in a murine model of asthma.
Topics: Amphiregulin; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Collagen; Disease Mode | 2007 |
Effects of long-term inhaled corticosteroids on skin collagen synthesis and thickness in asthmatic patients.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Biomarkers; Bl | 1998 |
Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics.
Topics: Administration, Oral; Adolescent; Adult; Aged; Alkaline Phosphatase; Amino Acids; Asthma; Biomarkers | 1999 |
The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma.
Topics: Acetylcholine; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; | 2001 |
[Study of hydroxyproline metabolism in inflammatory lung diseases].
Topics: Acute Disease; Adolescent; Adult; Aged; Asthma; Chronic Disease; Humans; Hydroxyproline; Middle Aged | 1978 |
[Role of lysosomal enzymes and free oxyproline in the diagnosis and evaluation of the effectiveness of treatment of bronchial asthma in children].
Topics: Asthma; beta-Galactosidase; beta-N-Acetylhexosaminidases; Child; Clinical Enzyme Tests; Glucuronidas | 1989 |
Insulin-like growth factor 1 and bone turnover in glucocorticoid-treated and control subjects.
Topics: Adult; Alkaline Phosphatase; Asthma; Bone and Bones; Female; Humans; Hydroxyproline; Insulin-Like Gr | 1989 |
Elimination of severe height growth suppression caused by treatment with betamethasone after switching to ACTH-depot in chronic bronchial asthma.
Topics: Adolescent; Adrenocorticotropic Hormone; Asthma; Betamethasone; Body Height; Delayed-Action Preparat | 1972 |
Corticosteroid osteoporosis.
Topics: Adult; Aged; Aging; Arthritis, Rheumatoid; Asthma; Autoanalysis; Bone and Bones; Calcium; Calcium Ra | 1973 |
Studies on hydroxyproline excretion and corticosteroid-induced dwarfism: treatment with human growth hormone.
Topics: Asthma; Child; Dwarfism; Female; Growth; Growth Hormone; Humans; Hydroxyproline; Prednisone; Triamci | 1966 |