hydroxyproline has been researched along with Alveolitis, Fibrosing in 529 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tuberostemonine significantly improved respiratory function in mice with bleomycin-induced pulmonary fibrosis, decreased cellular and lung hydroxyproline content, reduced inflammation and collagen deposition in cells and lung, and promoted an increase in the SLC7A11 and GPX4 proteins." | 8.84 | Tuberostemonine may enhance the function of the SLC7A11/glutamate antiporter to restrain the ferroptosis to alleviate pulmonary fibrosis. ( Cao, F; Liu, M; Liu, Y; Tang, A; Xu, C; Yang, C, 2024) |
| " Also, the effects of Pirfenidone on macrophage polarization and pulmonary fibrosis were evaluated in silicosis with early intervention and late treatment by histological examination, Enzyme-linked immunosorbent assay, Hydroxyproline assay, Western blot and Quantitative reverse transcription polymerase chain reaction." | 8.12 | Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways. ( Bo, C; Jia, Q; Li, M; Tang, Q; Xing, C; Zhang, Z, 2022) |
| "Paraquat (PQ) induces pulmonary fibrosis, a progressive lung disorder resulting in severe respiratory failure and death." | 7.91 | Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice. ( Khodayar, MJ; Mansouri, E; Mirzaee, S; Shirani, M; Zeinvand-Lorestani, M, 2019) |
| "Pirfenidone is known to slow the decline in vital capacity and increase survival in idiopathic pulmonary fibrosis (IPF)." | 7.88 | Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis. ( Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R, 2018) |
| "In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice." | 7.88 | Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression. ( Ghazi-Khansari, M; Heidari, MR; Iranpour, M; Mandegary, A; Pourgholamhossein, F; Pourgholi, L; Pournamdari, M; Poursalehi, HR; Rasooli, R; Samareh-Fekri, M, 2018) |
| " The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis." | 7.85 | Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017) |
| " Different doses of dioscin were gavaged to the animals 1 day after crystalline silica instillation to see the effect of dioscin on crystalline silica induced pulmonary fibrosis." | 7.85 | Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice. ( Chen, J; Chen, Y; Du, S; Li, C; Li, S; Liu, F; Lu, Y; Weng, D; Zhang, Y, 2017) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 7.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| "Tacrolimus (Tac) is an immunosuppressant that inhibits translocation of nuclear factor of activated T cells and has therapeutic potential for pulmonary fibrosis." | 7.83 | Therapeutic advantage of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmonary fibrosis mouse model. ( Choi, HG; Hwang, HS; Kim, B; Lee, C; Lee, ES; Lim, JL; Oh, KT; Seo, J; Thao, le Q; Youn, YS, 2016) |
| "The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats." | 7.83 | The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats. ( Arslanbas, E; Deveci, K; Elagoz, S; Gungor, H; Kara, H; Turgut, NH, 2016) |
| "Pulmonary fibrosis induced by paraquat (PQ) has caused a large number of human fatalities all over the world, especially in Asian region." | 7.83 | Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats. ( Goudarzi, M; Hemmati, AA; Hosseinzadeh, A; Houshmand, G; Javad-Mousavi, SA; Mehrabani, M; Mehrzadi, S; Rashidi Nooshabadi, MR, 2016) |
| "Paraquat (PQ) is one of the most widely used herbicides in the world and can cause pulmonary fibrosis in the cases with intoxication." | 7.81 | Losartan attenuates paraquat-induced pulmonary fibrosis in rats. ( Guo, F; Hu, XT; Li, J; Li, S; Liu, ZF; Su, L; Sun, YB, 2015) |
| "The present study evaluated the effect of epigallocatechin-3-gallate (EGCG), the most abundant catechin in green tea, on irradiation-induced pulmonary fibrosis and elucidated its mechanism of action." | 7.80 | The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats. ( Liu, Y; Sun, WL; Wang, L; Wang, Y; Wei, L; Yang, ZL; You, H; Zhang, WJ; Zheng, K, 2014) |
| "To observe the expression of leptin (LP) and its influence on pulmonary fibrosis in experimental rats with silicosis and the correlation between the expressions of leptin and HIF-1α." | 7.80 | [Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions]. ( Chen, B; Fan, D; Li, H; Li, Y; Pei, H; Zhang, M; Zhou, R; Zhu, S, 2014) |
| "This study aimed to investigate the pathogenesis mechanisms of bleomycin (BLM)-induced pulmonary fibrosis (PF) in Sprague-Dawley rats and explore the anti-fibrotic role of arsenic trioxide (As2O3) in preventing PF." | 7.80 | Arsenic trioxide prevents rat pulmonary fibrosis via miR-98 overexpression. ( Gao, SY; Li, YJ; Liu, WL; Lv, CJ; Pang, M; Wang, PY; Xie, SY; Zhou, X, 2014) |
| " Pulmonary hydroxyproline content (HPC), pulmonary connective tissue growth factor (CTGF) transcription and lung compliance (LC) were analysed to characterize pulmonary fibrosis." | 7.79 | Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats. ( Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R, 2013) |
| "Paraquat (PQ) poisoning has caused a large number of human fatalities due to the progressive and irreversible pulmonary fibrosis." | 7.79 | Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN. ( Bi, Y; Chen, J; Xiea, K; Zeng, T; Zhao, X; Zhong, Z, 2013) |
| "The effects of neferine, a bisbenzylisoquinline alkaloid extracted from the Chinese traditional medicine seed embryo of Nelumbo nucifera Gaertn, on amiodarone-induced pulmonary fibrosis in mice were evaluated." | 7.79 | Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. ( Liu, JD; Niu, CH; Wang, JL; Wang, Y; Xiao, JH, 2013) |
| " Bleomycin administration reduced the body weight, altered antioxidant status (such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione) while it increased the lung weight, hydroxyproline content, collagen deposition and lipid peroxidation." | 7.79 | Evaluating the inhibitory potential of sulindac against the bleomycin-induced pulmonary fibrosis in wistar rats. ( Brahmankar, M; Kushwah, L; Suresh, B; Verma, R, 2013) |
| "This study was carried out to highlight the role of PPARγ in the paraquat (PQ)-induced pulmonary fibrosis." | 7.79 | Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors. ( Khoramjouy, M; Malekinejad, H; Mehrabi, M; Rezaei-Golmisheh, A, 2013) |
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 7.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| "Resveratrol has a preventive potential on bleomycin-induced pulmonary fibrosis in prophylactic use; however, it was not studied in the treatment of the fibrosis." | 7.78 | Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats. ( Akgedik, R; Akgedik, S; Armutcu, F; Bozkurt, B; Karamanlı, H; Ozol, D; Uysal, S; Yıldırım, Z, 2012) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 7.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| " Intratracheal bleomycin administration resulted in pulmonary fibrosis 14 and 21 days posttreatment, as evidenced by increased hydroxyproline content in bleomycin group (255." | 7.76 | Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. ( Chang, Q; Chen, X; Guo, Q; Huang, Y; Wang, J; Wang, W; Wang, X; Xu, J; Zhang, S; Zhao, L, 2010) |
| "Metabolites of arachidonic acid such as prostacyclin (PGI2) have been shown to participate in the pathogenesis of pulmonary fibrosis by inhibiting the expression of pro-inflammatory and pro-fibrotic mediators." | 7.76 | A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice. ( Gao, J; Guo, Z; Huang, K; Jiang, L; Liu, Y; Xiang, R; Xiao, Y; Zhou, W; Zhu, Y, 2010) |
| "To observe the effect of tyrosine kinase depressor imatinib mesylate on pulmonary fibrosis (PF) induced by bleomycin in mice and explore its mechanism." | 7.74 | [Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice]. ( Li, L; Li, YQ, 2007) |
| "The most common cause of death from poisoning by the widely used, but highly toxic herbicide paraquat is respiratory failure from pulmonary fibrosis, which develops through pathological overproduction of extracellular matrix proteins such as the collagens." | 7.74 | An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T, 2007) |
| "To investigate the dynamic expression of placenta growth factor (PLGF) in the lungs with paraquat (PQ)-induced pulmonary fibrosis." | 7.74 | [Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model]. ( Dai, MS; Lin, LF; Zheng, MH, 2007) |
| " This study aimed to explore the effect of losartan, an angiotensin II type 1 receptor antagonist, on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease (CLD) and its possible mechanisms." | 7.74 | [Effect of losartan on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease]. ( Chen, N; Li, JJ; Xue, XD, 2007) |
| "To study the effect of losartan, an angiotensin II antagonist, on bleomycin-induced pulmonary fibrosis in rats and its possible mechanism." | 7.73 | Losartan attenuates bleomycin-induced pulmonary fibrosis in rats. ( Lu, Y; Yao, HW; Zhao, MH; Zhu, JP, 2006) |
| "These findings suggest that EM703 improves bleomycin-induced pulmonary fibrosis in mice by actions of anti-inflammation and regulation of TGF-beta signaling in lung fibroblasts." | 7.73 | EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts. ( Abe, S; Azuma, A; Hirata, Y; Inagaki, H; Kawada, T; Kudoh, S; Li, YJ; Matsuda, K; Omura, S; Shimizu, T; Sunazuka, T; Takahashi, S; Usuki, J, 2006) |
| "This study examined effects of S-allyl cysteine (SAC) on carbon tetrachloride (CCl4)-induced interstitial pulmonary fibrosis in Wistar rats." | 7.73 | S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats. ( Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T, 2006) |
| "To study the protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats." | 7.73 | [Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats]. ( Chen, WT; Li, ZH; Lin, TX; Lu, YS; Niu, JZ; Wang, JF; Zhou, G, 2006) |
| "Amiodarone (AM) is an efficacious antidysrhythmic agent that can cause numerous adverse effects, including potentially life-threatening pulmonary fibrosis." | 7.72 | Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction. ( Brien, JF; Card, JW; Massey, TE; Racz, WJ, 2003) |
| "To study the effects of panax notoginside (PNS) and methylprednisolone (solu-medrol) on the development of pulmonary fibrosis and the possible underlining mechanisms." | 7.71 | [The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis]. ( Cui, S; Li, X, 2002) |
| "We have reported that tranilast, an anti-allergic drug that inhibits chemical mediator release from mast cells, suppresses bleomycin (BLM)-induced pulmonary fibrosis in mice through mechanisms other than inhibiting chemical mediator release from mast cells." | 7.69 | Suppressive effects of tranilast on pulmonary fibrosis and activation of alveolar macrophages in mice treated with bleomycin: role of alveolar macrophages in the fibrosis. ( Kawada, K; Koda, A; Mori, H; Nagai, H; Tanaka, H, 1995) |
| "The objective of this study was to evaluate the effectiveness of erythromycin (EM) on bleomycin-induced pulmonary fibrosis in rats and its possible mechanisms." | 7.69 | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. ( Chen, B; Hou, XM; Jiang, L; Yu, R; Zhao, W, 1997) |
| "To investigate the effect of 3,4-DL-dehydroproline (DHP) on paraquat (PQ)-induced pulmonary fibrosis in beagle dogs, 25 beagles without distinction of sex were allocated at random into 2 groups; 17 dogs were PQ-dosed and 8 were saline-dosed." | 7.68 | Effect of dehydroproline as a collagen synthetic inhibitor in paraquat-induced pulmonary fibrosis in beagle dogs. ( Akahori, F; Masaoka, T; Nagata, T; Okinaka, T, 1993) |
| "Dimethyl sulfoxide (DMSO), a putative anti-inflammatory agent and free radical scavenger, was shown to protect against acute bleomycin-induced pulmonary fibrosis in the rat (Pepin and Langner, Biochem." | 7.67 | Effects of dimethyl sulfoxide (DMSO) on pulmonary fibrosis in rats and mice. ( Baer, KE; Haschek, WM; Rutherford, JE, 1989) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 7.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| "The purpose of this study was to determine whether Captopril (an angiotensin converting enzyme inhibitor) or D-penicillamine (an inhibitor of collagen crosslinking) can ameliorate pulmonary fibrosis induced by the plant alkaloid monocrotaline." | 7.67 | Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine. ( Dunne, M; Molteni, A; Solliday, NH; Ts'ao, CH; Ward, WF, 1985) |
| " Interview examination with BMRC questionnaire, X-ray examination and measurement of urinary hydroxyproline to creatinine ratio (HOP ratio) were carried out in order to elucidate the relationship between silicosis and urinary HOP ratio and to demonstrate the effect of smoking on pneumofibrosis." | 7.67 | [Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis]. ( Kasuga, H; Kato, Y; Matsuki, H; Osaka, F; Shima, S, 1986) |
| "Effect of peplomycin sulfate (PLM) on pulmonary fibrosis was examined." | 7.66 | Peplomycin sulfate and pulmonary fibrosis: hydroxyproline, uronic acid, proline hydroxylase and glucosamine 6-phosphate synthetase in lungs of hamsters treated with peplomycin. ( Hiramatsu, M; Kawaguchi, T; Kiuchi, H; Sekiya, S; Yamada, T; Yamamoto, K; Yoshida, A; Yu, SY, 1983) |
| "The purpose of this study was to examine whether development of pulmonary fibrosis in mice could be influenced by indomethacin, prednisolone or a proline analog." | 7.66 | The effect of indomethacin, prednisolone and cis-4-hydroxyproline on pulmonary fibrosis produced by butylated hydroxytoluene and oxygen. ( Kehrer, JP; Witschi, H, 1981) |
| "An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days." | 7.66 | Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979) |
| "Baicalin is an important flavonoid compound THAT is isolated from the Scutellaria baicalensis Georgi Chinese herb and plays a critical role in anti‑oxidative, anti‑inflammatory, anti‑infection and anti‑tumor functions." | 5.56 | Baicalin alleviates bleomycin‑induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway. ( Chen, D; Gao, Y; Li, C; Li, L; Li, Z; Liu, J; Lu, A; Mu, K; Ren, Y; Zhao, H, 2020) |
| " Treatment with either NaHS or BM-MSC leads to an inhibitory effect on pulmonary fibrosis as evidenced by improvement of histopathological studies, pulmonary function tests, reduction of inflammatory and fibrotic markers like Hydroxyproline, TNF α, TGF-β and caspase -3 together with downregulation miR-21 and increase lncRNA-GAS5 expression." | 5.51 | Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5. ( Abdelmonsif, DA; Ali, RG; Badae, NM; Nassar, SZ, 2022) |
| "Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and high mortality, posing a major threat to human health." | 5.51 | Therapeutic effects of the rhSOD2-Hirudin fusion protein on bleomycin-induced pulmonary fibrosis in mice. ( Breitzig, M; Czachor, A; Huang, L; Huang, M; Lei, S; Li, S; Mo, X; Shen, L; Sun, H; Tian, J; Wang, F; Yi, S; Zheng, Q, 2019) |
| "Pulmonary fibrosis is an irreversible lung disorder with predictable decline in lung function leading to respiratory insufficiency." | 5.51 | Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition. ( Bale, S; Godugu, C; Prashanth Goud, M; Pulivendala, G, 2019) |
| "Pulmonary fibrosis is a common outcome of various interstitial lung diseases." | 5.48 | Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway. ( He, Y; Jiang, Z; Liu, H; Mei, J; Shen, S; Tang, M, 2018) |
| "Hydroxysafflor yellow A (HSYA) is an active component of Carthamus tinctorius L." | 5.43 | Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice. ( Jin, M; Tan, L; Wang, L; Wu, Y; Zang, B, 2016) |
| "Pulmonary fibrosis is a chronic lung disease characterized by inflammation and collagen deposition, with an estimated mortality rate exceeding 70%." | 5.43 | Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. ( Choi, HG; Hwang, HS; Lee, C; Lee, EH; Lee, ES; Lee, S; Seo, J; Thao, LQ; Youn, YS, 2016) |
| "Pulmonary fibrosis is a progressive lung disorder with high mortality rate and limited successful treatment." | 5.43 | Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9. ( Abuelezz, SA; Hendawy, N; Osman, WM, 2016) |
| "Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis and high mortality rate." | 5.43 | Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of Caveolin-1 and TGF-β1 Signal Pathway. ( Huang, F; Ma, W; Zhan, H; Zhang, C; Zhang, H; Zhao, Z, 2016) |
| "This drug produces a dose-dependent pulmonary fibrosis (PF) in most patients as well as experimental animals through oxidative injury." | 5.42 | Protective effect of gallic acid against bleomycin-induced pulmonary fibrosis in rats. ( Arzi, A; Ghafourian, M; Hemmati, AA; Mansouri, MT; Nikbakht, J; Rezaie, A, 2015) |
| "Hydrogen sulfide (H2S) displays vasodilative, anti-oxidative, anti-inflammatory and cytoprotective activities." | 5.40 | Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance. ( Cao, H; Chu, L; Huang, X; Zhai, Y; Zhang, J; Zhang, X; Zhou, X, 2014) |
| "Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis." | 5.40 | Ameliorative effect of mepenzolate bromide against pulmonary fibrosis. ( Asano, T; Azuma, A; Kurotsu, S; Mizushima, T; Niino, T; Sugizaki, T; Suzuki, H; Tanaka, K, 2014) |
| "Currently, there is no satisfactory treatment for pulmonary fibrosis, and effective agents urgently need to be developed." | 5.39 | Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. ( Chen, Y; Gao, Y; Gu, Z; Jiang, X; Lu, J; Zhang, Y, 2013) |
| "Treatment with methyl palmitate attenuated silica-induced lung inflammation and fibrosis, as it significantly decreased lactate dehydrogenase (LDH) activity and the accumulation of the inflammatory cells in the bronchoalveolar lavage fluid (BALF)." | 5.39 | Protective effects of methyl palmitate against silica-induced pulmonary fibrosis in rats. ( Ammar, el-SM; El-Agamy, DS; Shalaby, AA; Sharawy, MH, 2013) |
| "Pulmonary fibrosis is a progressive and fatal lung disorder with high mortality rate." | 5.39 | Atorvastatin attenuates bleomycin-induced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway. ( Dang, XM; Ma, AQ; Yang, L; Zhu, B, 2013) |
| "Cerium compounds have been used as a diesel engine catalyst to lower the mass of diesel exhaust particles, but are emitted as cerium oxide (CeO(2)) nanoparticles in the diesel exhaust." | 5.38 | Induction of pulmonary fibrosis by cerium oxide nanoparticles. ( Barger, M; Castranova, V; Ma, JK; Ma, JY; Mercer, RR; Scabilloni, J; Schwegler-Berry, D, 2012) |
| "Montelukast treatment also decreased mRNA levels of IL-6, IL-10, IL-13, and TGF-β1, all of which were elevated in fibrotic lungs." | 5.37 | Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice. ( Okunishi, H; Shimbori, C; Shiota, N, 2011) |
| "Idiopathic pulmonary fibrosis is regarded as a lethal chronic disease accompanied with excessive collagen disposition." | 5.37 | (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a novel readily available and orally active glitazone, attenuates the bleomycin-induced pulmonary fibrosis in vivo. ( Chen, L; Chen, Z; Luo, Y; Ma, L; Ma, Y; Qi, B; Wang, G; Wei, X; Wei, Y; Zheng, H, 2011) |
| "Pravastatin was given through intraperitoneal injection." | 5.36 | Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis. ( Kim, JW; Kim, KH; Kim, SC; Kim, TJ; Kim, YH; Kim, YK; Kwon, SS; Lee, SH; Lee, SY; Rhee, CK; Yoon, HK, 2010) |
| "Suplatast tosilate is a Th2 cytokine inhibitor that is widely used as an asthma controller in Japan." | 5.35 | Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice. ( Fujitaka, K; Furonaka, M; Haruta, Y; Hattori, N; Ishikawa, N; Kohno, N; Senoo, T; Tanimoto, T; Yokoyama, A, 2009) |
| "Rats were given one dose of bleomycin in pulmonary fibrosis groups and saline in controls." | 5.32 | Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats. ( Akyol, O; Armutcu, F; Iraz, M; Kaplan, S; Kart, L; Ozen, S; Ozyurt, H; Sogut, S; Temel, I; Yildirim, Z, 2004) |
| "Treatment with pirfenidone significantly reduced the number of these cells compared with the corresponding BL group." | 5.32 | Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis. ( Abe, K; Fujii, T; Hayashi, T; Ishii, H; Kadota, J; Kakugawa, T; Kohno, S; Miyazaki, M; Mukae, H; Oku, H, 2004) |
| "It has potential of producing pulmonary fibrosis." | 5.31 | The role of sodium cromolyn in treatment of paraquat-induced pulmonary fibrosis in rat. ( Goldasteh, S; Hemmati, AA; Motlagh, ME; Nazari, Z, 2002) |
| "Batimastat treatment was effective in reducing MMP-2 and MMP-9 activity as well as the tissue inhibitor of metalloproteinase-1 (TIMP-1) level in BAL." | 5.31 | Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat. ( Boichot, E; Caulet-Maugendre, S; Corbel, M; Germain, N; Lagente, V; Molet, S, 2001) |
| "Amiodarone (AM) is an antidysrhythmic agent with a propensity to cause pulmonary toxicity, including potentially fatal fibrosis." | 5.31 | Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis. ( Bennett, BM; Brien, JF; Chung, WH; Massey, TE; Racz, WJ, 2001) |
| "Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes." | 5.30 | The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998) |
| "Pulmonary fibrosis was first detected at 15 days and was progressive with time elapsed after trichloroethylene exposure." | 5.29 | Trichloroethylene induces pulmonary fibrosis in mice. ( Forkert, L; Forkert, PG, 1994) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 5.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "Interstitial pulmonary fibrosis induced by bleomycin (BL) involves the production of reactive oxygen species and the impairment of repair of damaged epithelial cells." | 5.28 | Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. ( Giri, SN; Hyde, DM; Li, C; Wang, QJ, 1991) |
| "In the present paper, we evidenced that pulmonary fibrosis could be induced in genetically mast cell-deficient WBB6F1-W/Wv mice as well as WBB6F1-(+/+) mice having mast cells normally by the treatment with bleomycin (BLM, 5 mg/kg, i." | 5.28 | Bleomycin-induced pulmonary fibrosis in genetically mast cell-deficient WBB6F1-W/Wv mice and mechanism of the suppressive effect of tranilast, an antiallergic drug inhibiting mediator release from mast cells, on fibrosis. ( Kawada, K; Koda, A; Mori, H; Sakamoto, O; Uesugi, Y; Zhang, P, 1991) |
| "A model of pulmonary fibrosis caused by a single intratracheal injection 0." | 5.28 | [A study on the inhibition effect of tetrandrine on the pingyangmycinum induced pulmonary fibrosis]. ( Jin, H, 1991) |
| "Interstitial pulmonary fibrosis is characterized by an abnormal accumulation of fibroblasts with a resultant increase in lung collagen content." | 5.27 | The effect of cyclosporin A on pulmonary fibrosis induced by butylated hydroxytoluene, bleomycin and beryllium sulfate. ( Lindenschmidt, RC; Sendelbach, LE; Witschi, HP, 1985) |
| "Two agents that produce pulmonary fibrosis were selected for this study." | 5.27 | The combination of ozone and silica on the development of pulmonary fibrosis. ( Drew, RT; Osheroff, MR; Shiotsuka, RN; Yermakoff, JK, 1986) |
| "Tuberostemonine significantly improved respiratory function in mice with bleomycin-induced pulmonary fibrosis, decreased cellular and lung hydroxyproline content, reduced inflammation and collagen deposition in cells and lung, and promoted an increase in the SLC7A11 and GPX4 proteins." | 4.84 | Tuberostemonine may enhance the function of the SLC7A11/glutamate antiporter to restrain the ferroptosis to alleviate pulmonary fibrosis. ( Cao, F; Liu, M; Liu, Y; Tang, A; Xu, C; Yang, C, 2024) |
| " Additionally, FcεRI-deficient mice showed a significantly lower score of pulmonary fibrosis than wild-type mice following exposure to silica, with significantly lower hydroxyproline content and expression of fibrotic genes Col1a1 and Fn1." | 4.12 | FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis. ( Chen, Y; Hou, L; Hu, H; Jiang, X; Li, Z; Pang, J; Song, M; Wang, C; Wang, J; Yang, J; Yang, P; Zhang, H; Zhang, T; Zhang, Z; Zou, X, 2022) |
| " Also, the effects of Pirfenidone on macrophage polarization and pulmonary fibrosis were evaluated in silicosis with early intervention and late treatment by histological examination, Enzyme-linked immunosorbent assay, Hydroxyproline assay, Western blot and Quantitative reverse transcription polymerase chain reaction." | 4.12 | Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways. ( Bo, C; Jia, Q; Li, M; Tang, Q; Xing, C; Zhang, Z, 2022) |
| "CAE oral administration lowered hydroxyproline content, inhibited the collagen deposition including expressions of collagen I and III, and relieved bleomycin-induced pulmonary fibrosis in mice model." | 4.02 | Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis. ( Chen, XY; Feng, FC; He, HL; Li, RF; Xu, Y; Zhou, XM, 2021) |
| "To evaluate the immune regulatory and anti-fibrosis function of thalidomide (Thal) in systemic sclerosis (SSc), we investigated the effects of Thal on: (a) Th17 and Treg cell production; (b) related factors expression; and (c) transforming growth factor (TGF)-β1/Smad3 pathway, using a mouse model of SSc." | 3.96 | Effects of thalidomide on Th17, Treg cells and TGF-β1/Smad3 pathway in a mouse model of systemic sclerosis. ( Lei, L; Li, X; Lu, Y; Tao, Z; Wen, J; Zhao, C; Zheng, L, 2020) |
| " In the current study, rutin has been investigated for its ability to ameliorate BLM-induced pulmonary fibrosis." | 3.96 | Protective effect of rutin against bleomycin induced lung fibrosis: Involvement of TGF-β1/α-SMA/Col I and III pathway. ( Bai, L; Gong, C; Li, A; Ning, X; Wang, Z, 2020) |
| " After observing the pulmonary function indexes of the rats on the 3rd, 7th and 14th days after modeling, the rats were sacrificed by cervical dislocation, the pulmonary inflammation and fibrosis of the rats were observed, and the HYP (hydroxyproline) content and miR-223 expression level were determined." | 3.96 | Expression and significance of miR-223 in rats with pulmonary fibrosis. ( Ju, P; Li, YM; Qu, SJ; Shen, WP; Song, ZZ; Zhao, L, 2020) |
| "Paraquat (PQ) induces pulmonary fibrosis, a progressive lung disorder resulting in severe respiratory failure and death." | 3.91 | Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice. ( Khodayar, MJ; Mansouri, E; Mirzaee, S; Shirani, M; Zeinvand-Lorestani, M, 2019) |
| "Nickel oxide nanoparticles (Nano NiO) could induce pulmonary fibrosis, however, the mechanisms are still unknown." | 3.91 | TGF-β1 mediated MAPK signaling pathway promotes collagen formation induced by Nano NiO in A549 cells. ( Chang, X; Li, C; Li, S; Sun, Y; Tian, M; Zhang, Q, 2019) |
| "Pirfenidone is known to slow the decline in vital capacity and increase survival in idiopathic pulmonary fibrosis (IPF)." | 3.88 | Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis. ( Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R, 2018) |
| " In vivo, intratracheal treatment with Lv-miR-29c significantly increased expression of miR-29c, and reduced expression of β-catenin, matrix metalloproteinase (MMP)-2, and MMP-9 in the lung and levels of transforming growth factor-beta 1 (TGF-β1) and interleukin-6 (IL-6) in bronchoalveolar lavage fluid, and notably attenuated pulmonary fibrosis as evidenced by hydroxyproline content in silica-administered mice." | 3.88 | Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice. ( Liu, J; Wang, FS; Wang, X; Xu, K; Yang, XY; Zeng, Q, 2018) |
| "In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice." | 3.88 | Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression. ( Ghazi-Khansari, M; Heidari, MR; Iranpour, M; Mandegary, A; Pourgholamhossein, F; Pourgholi, L; Pournamdari, M; Poursalehi, HR; Rasooli, R; Samareh-Fekri, M, 2018) |
| " The purpose of this study was to test in vivo the antifibrotic activity of Bosutinib (SKI-606), a second generation c-Abl and Src kinase inhibitor, on TGF-β induced cutaneous and pulmonary fibrosis." | 3.88 | Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib). ( Jimenez, SA; Wermuth, PJ, 2018) |
| " The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis." | 3.85 | Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017) |
| " Different doses of dioscin were gavaged to the animals 1 day after crystalline silica instillation to see the effect of dioscin on crystalline silica induced pulmonary fibrosis." | 3.85 | Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice. ( Chen, J; Chen, Y; Du, S; Li, C; Li, S; Liu, F; Lu, Y; Weng, D; Zhang, Y, 2017) |
| "treatment." | 3.83 | Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airway mucus and bleomycin-\ induced pulmonary fibrosis in rats. ( Choong, JL; Hyo-Seok, S; Hyun, JL, 2016) |
| "The objective of this study was to study the effect of roflumilast on airway inflammation and remodelling in a murine model of chronic asthma." | 3.83 | Effect of roflumilast on airway remodelling in a murine model of chronic asthma. ( Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK, 2016) |
| "Tacrolimus (Tac) is an immunosuppressant that inhibits translocation of nuclear factor of activated T cells and has therapeutic potential for pulmonary fibrosis." | 3.83 | Therapeutic advantage of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmonary fibrosis mouse model. ( Choi, HG; Hwang, HS; Kim, B; Lee, C; Lee, ES; Lim, JL; Oh, KT; Seo, J; Thao, le Q; Youn, YS, 2016) |
| "The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats." | 3.83 | The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats. ( Arslanbas, E; Deveci, K; Elagoz, S; Gungor, H; Kara, H; Turgut, NH, 2016) |
| "Pulmonary fibrosis induced by paraquat (PQ) has caused a large number of human fatalities all over the world, especially in Asian region." | 3.83 | Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats. ( Goudarzi, M; Hemmati, AA; Hosseinzadeh, A; Houshmand, G; Javad-Mousavi, SA; Mehrabani, M; Mehrzadi, S; Rashidi Nooshabadi, MR, 2016) |
| "Paraquat (PQ) is one of the most widely used herbicides in the world and can cause pulmonary fibrosis in the cases with intoxication." | 3.81 | Losartan attenuates paraquat-induced pulmonary fibrosis in rats. ( Guo, F; Hu, XT; Li, J; Li, S; Liu, ZF; Su, L; Sun, YB, 2015) |
| "Histological analysis and hydroxyproline assay revealed that bleomycin successfully induced pulmonary fibrosis, and that 20 μg of oral E4 peptide ameliorated the fibrosis." | 3.81 | An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model. ( Feghali-Bostwick, C; Mlakar, L; Nishimoto, T; Takihara, T, 2015) |
| "The present study evaluated the effect of epigallocatechin-3-gallate (EGCG), the most abundant catechin in green tea, on irradiation-induced pulmonary fibrosis and elucidated its mechanism of action." | 3.80 | The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats. ( Liu, Y; Sun, WL; Wang, L; Wang, Y; Wei, L; Yang, ZL; You, H; Zhang, WJ; Zheng, K, 2014) |
| " The granuloma area, hepatic hydroxyproline (HYP) level and hepatic fibrosis of the protein therapeutic groups were significantly smaller than those of the positive control group (P<0." | 3.80 | The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease. ( Chu, D; Yao, Y; Zhou, C, 2014) |
| "To observe the expression of leptin (LP) and its influence on pulmonary fibrosis in experimental rats with silicosis and the correlation between the expressions of leptin and HIF-1α." | 3.80 | [Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions]. ( Chen, B; Fan, D; Li, H; Li, Y; Pei, H; Zhang, M; Zhou, R; Zhu, S, 2014) |
| "This study aimed to investigate the pathogenesis mechanisms of bleomycin (BLM)-induced pulmonary fibrosis (PF) in Sprague-Dawley rats and explore the anti-fibrotic role of arsenic trioxide (As2O3) in preventing PF." | 3.80 | Arsenic trioxide prevents rat pulmonary fibrosis via miR-98 overexpression. ( Gao, SY; Li, YJ; Liu, WL; Lv, CJ; Pang, M; Wang, PY; Xie, SY; Zhou, X, 2014) |
| " Pulmonary hydroxyproline content (HPC), pulmonary connective tissue growth factor (CTGF) transcription and lung compliance (LC) were analysed to characterize pulmonary fibrosis." | 3.79 | Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats. ( Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R, 2013) |
| "Paraquat (PQ) poisoning has caused a large number of human fatalities due to the progressive and irreversible pulmonary fibrosis." | 3.79 | Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN. ( Bi, Y; Chen, J; Xiea, K; Zeng, T; Zhao, X; Zhong, Z, 2013) |
| "Anti-KL-6 antibody significantly reduced the number of alveolar inflammatory leukocytes (total and differential counts) in BALF of mice with bleomycin-induced pulmonary fibrosis as well as the content of hydroxyproline in the lung tissues." | 3.79 | Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6. ( Bian, W; Ding, F; Gu, J; Rong, Z; Shen, C; Xu, L; Yang, D; Zhu, S, 2013) |
| "To study the potential of high-dose N-acetylcysteine (NAC) to attenuate silica-induced pulmonary fibrosis in the rat." | 3.79 | High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat. ( Jiang, H; Yin, G; Zhang, C; Zhang, H, 2013) |
| "The effects of neferine, a bisbenzylisoquinline alkaloid extracted from the Chinese traditional medicine seed embryo of Nelumbo nucifera Gaertn, on amiodarone-induced pulmonary fibrosis in mice were evaluated." | 3.79 | Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. ( Liu, JD; Niu, CH; Wang, JL; Wang, Y; Xiao, JH, 2013) |
| " Bleomycin administration reduced the body weight, altered antioxidant status (such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione) while it increased the lung weight, hydroxyproline content, collagen deposition and lipid peroxidation." | 3.79 | Evaluating the inhibitory potential of sulindac against the bleomycin-induced pulmonary fibrosis in wistar rats. ( Brahmankar, M; Kushwah, L; Suresh, B; Verma, R, 2013) |
| "This study was carried out to highlight the role of PPARγ in the paraquat (PQ)-induced pulmonary fibrosis." | 3.79 | Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors. ( Khoramjouy, M; Malekinejad, H; Mehrabi, M; Rezaei-Golmisheh, A, 2013) |
| " CAE treatment significantly increased rat weight gain, ameliorated alveolitis and pulmonary fibrosis degree, and lowered hydroxyproline contents in both serum and lung tissues." | 3.79 | Inhibitory effects of alkaline extract of Citrus reticulata on pulmonary fibrosis. ( Li, JX; Liu, YM; Wen, GY; Zhao, Y; Zhou, XM, 2013) |
| "Cohorts of animals were culled at 3, 7, 14 and 28 days to semi-quantitatively score the lung for fibrosis, and quantitate levels of hydroxyproline in the lung." | 3.78 | Assessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography. ( Dickinson, H; Jenkin, G; Lim, R; Milton, PL, 2012) |
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 3.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| "Resveratrol has a preventive potential on bleomycin-induced pulmonary fibrosis in prophylactic use; however, it was not studied in the treatment of the fibrosis." | 3.78 | Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats. ( Akgedik, R; Akgedik, S; Armutcu, F; Bozkurt, B; Karamanlı, H; Ozol, D; Uysal, S; Yıldırım, Z, 2012) |
| " Blocking oxidative stress with N-acetylcysteine attenuated whole lung inflammation but had no effect on total lung hydroxyproline." | 3.78 | Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice. ( Auten, RL; Brass, DM; Dunkel, MK; Fattman, CL; Hollingsworth, JW; Latoche, JD; Li, Z; Potts-Kant, E; Reilly, SM; Spencer, JC, 2012) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 3.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| " Intratracheal bleomycin administration resulted in pulmonary fibrosis 14 and 21 days posttreatment, as evidenced by increased hydroxyproline content in bleomycin group (255." | 3.76 | Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. ( Chang, Q; Chen, X; Guo, Q; Huang, Y; Wang, J; Wang, W; Wang, X; Xu, J; Zhang, S; Zhao, L, 2010) |
| "Metabolites of arachidonic acid such as prostacyclin (PGI2) have been shown to participate in the pathogenesis of pulmonary fibrosis by inhibiting the expression of pro-inflammatory and pro-fibrotic mediators." | 3.76 | A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice. ( Gao, J; Guo, Z; Huang, K; Jiang, L; Liu, Y; Xiang, R; Xiao, Y; Zhou, W; Zhu, Y, 2010) |
| " As the index of the severity of pulmonary fibrosis, the content of hydroxyproline in lungs was analyzed by chloramine T method." | 3.76 | [Baicalin prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats]. ( Chen, C; Chen, XL; Hu, YY; Jia, H; Yun, XJ, 2010) |
| "We investigated the potential usefulness of vesnarinone, a novel cytokine inhibitor, for the treatment of lung fibrosis using a murine model of bleomycin (BLM)-induced pulmonary fibrosis." | 3.75 | Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin. ( Abe, S; Hino, T; Hosokawa, T; Inage, M; Kato, S; Nakamura, H; Ogura, M; Saito, H; Sata, M; Takabatake, N; Terashita, K; Tomoike, H, 2009) |
| " AGEs level in lung tissue was determined by ELISA and pulmonary fibrosis was evaluated by Ashcroft score and hydroxyproline assay." | 3.75 | Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats. ( Chen, L; Chen, YJ; Li, JQ; Liu, DS; Liu, L; Sun, BB; Wang, T; Wang, X; Wen, FQ; Xu, D; Zhang, SF, 2009) |
| " The analyses of the rat body weight, hydroxyproline levels in serum and lung, scores of alveolitis and fibrosis, as well as the expression of transforming growth factor-beta(1) (TGF-beta(1)) at the protein and the messenger ribonucleic acid (mRNA) levels in lung were performed." | 3.75 | Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis. ( He, CC; Huang, MM; Li, JX; Zhou, XM, 2009) |
| "Administration of curcumin in different doses improved lung functions of BLM-induced fibrotic rats in the all experimental days; and it decreased the concentration of hydroxyproline in lung homogenates compared with those levels in model control group; and it also lessened the hyperplasia of BLM-induced pulmonary fibrosis in rats." | 3.74 | [Effects of curcumin on bleomycin-induced damages in pulmonary functions in rats]. ( Niu, JZ; Tang, BH; Wang, JF; Zhao, CJ; Zhou, G, 2008) |
| "To observe the effect of tyrosine kinase depressor imatinib mesylate on pulmonary fibrosis (PF) induced by bleomycin in mice and explore its mechanism." | 3.74 | [Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice]. ( Li, L; Li, YQ, 2007) |
| "The most common cause of death from poisoning by the widely used, but highly toxic herbicide paraquat is respiratory failure from pulmonary fibrosis, which develops through pathological overproduction of extracellular matrix proteins such as the collagens." | 3.74 | An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T, 2007) |
| "To investigate the dynamic expression of placenta growth factor (PLGF) in the lungs with paraquat (PQ)-induced pulmonary fibrosis." | 3.74 | [Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model]. ( Dai, MS; Lin, LF; Zheng, MH, 2007) |
| " This study aimed to explore the effect of losartan, an angiotensin II type 1 receptor antagonist, on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease (CLD) and its possible mechanisms." | 3.74 | [Effect of losartan on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease]. ( Chen, N; Li, JJ; Xue, XD, 2007) |
| "Although paraquat (PQ) is widely known to induce pulmonary fibrosis, the molecular mechanisms are poorly understood." | 3.74 | Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats. ( Akahori, F; Kasahara, Y; Sakaguchi, K; Satomi, Y, 2007) |
| "We examined effects of the AT1 antagonist (AT1A) olmesartan medoxomil (olmesartan) and the AT2 antagonist (AT2A) PD-123319 on BLM-induced pulmonary fibrosis, which was evaluated by Ashcroft's pathological scoring and hydroxyproline content of lungs." | 3.74 | Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice. ( Fujimura, M; Ichikawa, Y; Inuzuka, K; Nakao, S; Nishizawa, Y; Tagami, A; Takato, H; Waseda, Y; Yasui, M, 2008) |
| "To study the effect of losartan, an angiotensin II antagonist, on bleomycin-induced pulmonary fibrosis in rats and its possible mechanism." | 3.73 | Losartan attenuates bleomycin-induced pulmonary fibrosis in rats. ( Lu, Y; Yao, HW; Zhao, MH; Zhu, JP, 2006) |
| "These findings suggest that EM703 improves bleomycin-induced pulmonary fibrosis in mice by actions of anti-inflammation and regulation of TGF-beta signaling in lung fibroblasts." | 3.73 | EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts. ( Abe, S; Azuma, A; Hirata, Y; Inagaki, H; Kawada, T; Kudoh, S; Li, YJ; Matsuda, K; Omura, S; Shimizu, T; Sunazuka, T; Takahashi, S; Usuki, J, 2006) |
| "Decreased fibrinolytic function favors the development of pulmonary fibrosis." | 3.73 | Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis. ( Adachi, Y; Broze, GJ; Bruno, NE; D'Alessandro-Gabazza, CN; Fujimoto, H; Gabazza, EC; Kasper, M; Morser, J; Nagashima, M; Nakahara, H; Nishii, Y; Suzuki, K; Taguchi, O; Yano, Y, 2006) |
| "This study examined effects of S-allyl cysteine (SAC) on carbon tetrachloride (CCl4)-induced interstitial pulmonary fibrosis in Wistar rats." | 3.73 | S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats. ( Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T, 2006) |
| "To study the protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats." | 3.73 | [Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats]. ( Chen, WT; Li, ZH; Lin, TX; Lu, YS; Niu, JZ; Wang, JF; Zhou, G, 2006) |
| "To investigate the optimal dosage of pirfenidone for the treatment of pulmonary fibrosis induced by bleomycin in Wistar rats, and the alteration of expressions of transforming growth factor beta-1 (TGF-beta 1), tissue inhibitor of metalloproteinase-1 (TIMP-1), and matrix metalloproteinase-13 (MMP-13) in lung tissue." | 3.73 | Low dose pirfenidone suppresses transforming growth factor beta-1 and tissue inhibitor of metalloproteinase-1, and protects rats from lung fibrosis induced by bleomycina. ( Gu, L; Guo, ZJ; Tian, XL; Yao, W; Zhu, YJ, 2006) |
| "Amiodarone (AM) is an efficacious antidysrhythmic agent that can cause numerous adverse effects, including potentially life-threatening pulmonary fibrosis." | 3.72 | Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction. ( Brien, JF; Card, JW; Massey, TE; Racz, WJ, 2003) |
| " This study examines the activity of the antioxidant N-acetylcysteine on bleomycin-induced pulmonary fibrosis in rats with emphasis on the early inflammatory phase." | 3.72 | In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats. ( Blesa, S; Bulbena, O; Closa, D; Cortijo, J; Estrela, JM; Martinez-Losa, M; Morcillo, EJ; Prats, N; Serrano-Mollar, A, 2003) |
| " Intratracheal AM administration resulted in pulmonary fibrosis 21 days posttreatment, as evidenced by an increased hydroxyproline content and histological damage." | 3.72 | Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity. ( Brien, JF; Card, JW; Margolin, SB; Massey, TE; Racz, WJ, 2003) |
| " The effect of the AT1 antagonist on pulmonary fibrosis was studied by analysis of bronchoalveolar lavage (BAL) fluid, histopathology, and hydroxyproline assay." | 3.72 | Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist. ( Abe, S; Chiba, H; Otsuka, M; Shiratori, M; Takahashi, H, 2004) |
| "To study the injury effect of ammonium perchlorate (AP) to lung and to explore whether AP can cause pulmonary fibrosis." | 3.72 | [Study on the injury effect of ammonium perchlorate to lung]. ( Chu, Q; Peng, K; Yang, H; Zhao, S, 2004) |
| "To study the effects of panax notoginside (PNS) and methylprednisolone (solu-medrol) on the development of pulmonary fibrosis and the possible underlining mechanisms." | 3.71 | [The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis]. ( Cui, S; Li, X, 2002) |
| " IL-12p40(-/-) mice treated with BLM intratracheally showed less pulmonary mononuclear cell inflammation at Day 7 than wild-type controls, whereas pulmonary fibrosis and hydroxyproline content were increased in IL-12p40(-/-) mice at Day 14." | 3.71 | IL-12p40(-/-) mice treated with intratracheal bleomycin exhibit decreased pulmonary inflammation and increased fibrosis. ( Jain, F; Kradin, R; Sakamoto, H; Zhao, LH, 2002) |
| " Pulmonary fibrosis was evaluated by measuring alveolar septal wall thickness and the hydroxyproline content of lungs by immunohistochemical staining of lung sections for collagen III and by Masson's trichrome staining of lung sections." | 3.71 | Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice. ( Geng, L; Hallahan, DE; Shyr, Y, 2002) |
| " Fibrosis was associated with formation of granulomas, increase in lung hydroxyproline, and sustained increases in tissue tumor necrosis factor-alpha and transforming growth factor-beta." | 3.70 | Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses. ( Franco, L; Gomez, BL; Graybill, JR; Najvar, L; Restrepo, A; Restrepo, S, 1998) |
| " Histology and hydroxyproline analysis showed that BLM induced pulmonary fibrosis in C57BL/6 and (C57BL/6 x BALB/c)F1 mice, whereas BALB/c mice were resistant to the disease." | 3.70 | T cell independence of bleomycin-induced pulmonary fibrosis. ( Cohen, DA; Hao, H; Helene, M; Kaplan, AM; Lake-Bullock, V; Zhu, J, 1999) |
| "The purpose of the present study was to clarify the consecutive changes and roles of hyaluronan (HA), interleukin-8 (IL-8) and collagen production by lung fibroblasts in the course of pulmonary fibrosis." | 3.70 | [In vitro studies on the bioactive materials released by lung fibroblasts in experimental pulmonary fibrosis]. ( Hou, X; Lü, C; Yu, R; Zhao, H, 1999) |
| "08 U) or silica (2 mg) to mice leads, after 15 days, to a patchy pulmonary fibrosis associated with a significant increase of the lung hydroxyproline." | 3.69 | Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. ( Piguet, PF; Vesin, C, 1994) |
| "We have reported that tranilast, an anti-allergic drug that inhibits chemical mediator release from mast cells, suppresses bleomycin (BLM)-induced pulmonary fibrosis in mice through mechanisms other than inhibiting chemical mediator release from mast cells." | 3.69 | Suppressive effects of tranilast on pulmonary fibrosis and activation of alveolar macrophages in mice treated with bleomycin: role of alveolar macrophages in the fibrosis. ( Kawada, K; Koda, A; Mori, H; Nagai, H; Tanaka, H, 1995) |
| "Amiodarone (AD) has been shown to produce a transient pulmonary fibrosis in hamsters after intratracheal (i." | 3.69 | Pulmonary responses to amiodarone in hamsters: comparison of intratracheal and oral administrations. ( Blake, TL; Reasor, MJ, 1995) |
| "Amiodarone (AM) is an effective antidysrhythmic agent, the use of which is limited because of the drug's potential for causing life-threatening pulmonary fibrosis." | 3.69 | Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster. ( Brien, JF; Chatla, N; Kabalka, GW; Leeder, RG; Massey, TE; Rafeiro, E, 1994) |
| "In the multiple-dose bleomycin-hamster model of pulmonary fibrosis, combined treatment with taurine and niacin blocks the increase in lung collagen deposition." | 3.69 | Mechanism of antifibrotic effect of taurine and niacin in the multidose bleomycin-hamster model of lung fibrosis: inhibition of lysyl oxidase and collagenase. ( Blaisdell, RJ; Giri, SN, 1995) |
| " We tested this hypothesis by measuring annexin I levels, hydroxyproline content and ultrastructural changes in radiation-induced pulmonary fibrosis in rat." | 3.69 | Annexin I in fibrotic rat lung and cultured lung fibroblasts following irradiation. ( Molteni, A; Taylor, JM; Ts'ao, C; Tsao, FH; Ward, WF, 1997) |
| "The antifibrotic potential of pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) was examined in a single intratracheal bleomycin dose hamster model of pulmonary fibrosis." | 3.69 | Pirfenidone attenuates bleomycin-induced changes in pulmonary functions in hamsters. ( Giri, S; Mansoor, JK; Schelegle, ES, 1997) |
| "The objective of this study was to evaluate the effectiveness of erythromycin (EM) on bleomycin-induced pulmonary fibrosis in rats and its possible mechanisms." | 3.69 | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. ( Chen, B; Hou, XM; Jiang, L; Yu, R; Zhao, W, 1997) |
| "To investigate the effect of 3,4-DL-dehydroproline (DHP) on paraquat (PQ)-induced pulmonary fibrosis in beagle dogs, 25 beagles without distinction of sex were allocated at random into 2 groups; 17 dogs were PQ-dosed and 8 were saline-dosed." | 3.68 | Effect of dehydroproline as a collagen synthetic inhibitor in paraquat-induced pulmonary fibrosis in beagle dogs. ( Akahori, F; Masaoka, T; Nagata, T; Okinaka, T, 1993) |
| " The data presented here demonstrate that BALB/c, ICR and C57BL/6NHsd mice, with LD50s of 1739, 1243 and 917 respectively, exhibit similar time courses of repair (as assessed by the incorporation of radiolabelled thymidine into DNA) and pulmonary fibrosis (as assessed by lung hydroxyproline content) when given a single 400 mg/kg dose of BHT." | 3.68 | Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene. ( DiGiovanni, J; Kehrer, JP, 1990) |
| " More than 4 times the curative dose in this acute model of infection does not induce significant alterations of lung hydroxyproline levels, which are known to directly correlate with histopathological criteria of pulmonary fibrosis." | 3.67 | Bleomycin for the cure of Trypanosoma brucei brucei infections in mice: lack of pulmonary toxicity. ( Bacchi, CJ; Chovan, JP; Diccianni, MB; Nathan, HC; Raisfeld-Danse, IH, 1986) |
| "Dimethyl sulfoxide (DMSO), a putative anti-inflammatory agent and free radical scavenger, was shown to protect against acute bleomycin-induced pulmonary fibrosis in the rat (Pepin and Langner, Biochem." | 3.67 | Effects of dimethyl sulfoxide (DMSO) on pulmonary fibrosis in rats and mice. ( Baer, KE; Haschek, WM; Rutherford, JE, 1989) |
| " Lung angiotensin converting enzyme (ACE) activity and plasminogen activator (PLA) activity were measured as indices of pulmonary endothelial function; and lung hydroxyproline (HP) content served as an index of pulmonary fibrosis." | 3.67 | Radiation-induced pulmonary endothelial dysfunction and hydroxyproline accumulation in four strains of mice. ( Franko, AJ; Hinz, JM; Sharplin, J; Ward, WF, 1989) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 3.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| "The purpose of this study was to determine whether Captopril (an angiotensin converting enzyme inhibitor) or D-penicillamine (an inhibitor of collagen crosslinking) can ameliorate pulmonary fibrosis induced by the plant alkaloid monocrotaline." | 3.67 | Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine. ( Dunne, M; Molteni, A; Solliday, NH; Ts'ao, CH; Ward, WF, 1985) |
| "Pulmonary fibrosis is a consequence of severe injury from some toxic agents including high doses of ozone." | 3.67 | Effects of chronic exposure to ozone on collagen in rat lung. ( Kehrer, JP; Smiler, KL; White, DM; Wright, ES, 1988) |
| "We describe a model of pulmonary fibrosis in which doses of paraquat ranging from 0." | 3.67 | Unilateral paraquat-induced lung fibrosis: evolution of changes in lung fibronectin and collagen after graded degrees of lung injury. ( Dubaybo, BA; Durr, RA; Thet, LA, 1987) |
| " Interview examination with BMRC questionnaire, X-ray examination and measurement of urinary hydroxyproline to creatinine ratio (HOP ratio) were carried out in order to elucidate the relationship between silicosis and urinary HOP ratio and to demonstrate the effect of smoking on pneumofibrosis." | 3.67 | [Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis]. ( Kasuga, H; Kato, Y; Matsuki, H; Osaka, F; Shima, S, 1986) |
| " Interestingly, MP did not protect against the BHT-induced pulmonary fibrosis, measured as total lung hydroxyproline content, irrespective of the time between BHT challenge and MP treatment." | 3.67 | Protection by methylprednisolone against butylated hydroxytoluene-induced pulmonary damage and impairment of microsomal monooxygenase activities in the mouse: lack of effect on fibrosis. ( Goochee, JM; Gram, TE; Lowe, MC; Mimnaugh, EG; Okine, LK, 1986) |
| "We investigated the effect of the proline analogue cis-hydroxyproline on pulmonary fibrosis produced by intratracheal administration of bleomycin in hamsters." | 3.66 | Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline. ( Berg, RA; Edelman, NH; Ianni, BD; Kerr, JS; Pietra, GG; Prockop, DJ; Riley, DJ, 1981) |
| "Effect of peplomycin sulfate (PLM) on pulmonary fibrosis was examined." | 3.66 | Peplomycin sulfate and pulmonary fibrosis: hydroxyproline, uronic acid, proline hydroxylase and glucosamine 6-phosphate synthetase in lungs of hamsters treated with peplomycin. ( Hiramatsu, M; Kawaguchi, T; Kiuchi, H; Sekiya, S; Yamada, T; Yamamoto, K; Yoshida, A; Yu, SY, 1983) |
| "The purpose of this study was to examine whether development of pulmonary fibrosis in mice could be influenced by indomethacin, prednisolone or a proline analog." | 3.66 | The effect of indomethacin, prednisolone and cis-4-hydroxyproline on pulmonary fibrosis produced by butylated hydroxytoluene and oxygen. ( Kehrer, JP; Witschi, H, 1981) |
| "An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days." | 3.66 | Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979) |
| "Paraquat, bipyridilium herbicide know to cause pulmonary fibrosis, was injected IP into rats." | 3.66 | Paraquat-induced changes in the rate of collagen biosynthesis by rat lung explants. ( Greenberg, DB; Last, JA; Lyons, SA, 1978) |
| "Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by irreversible fibrosis and destruction of the alveolar structure." | 1.72 | Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model. ( Hwang, DW; Ko, MK; Lee, M; Piao, C; Zhuang, C, 2022) |
| "However, the effect of APS on pulmonary fibrosis (PF) remains unknown." | 1.56 | Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation. ( An, X; Lin, S; Sui, X; Xu, L; Zhang, R, 2020) |
| "Baicalin is an important flavonoid compound THAT is isolated from the Scutellaria baicalensis Georgi Chinese herb and plays a critical role in anti‑oxidative, anti‑inflammatory, anti‑infection and anti‑tumor functions." | 1.56 | Baicalin alleviates bleomycin‑induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway. ( Chen, D; Gao, Y; Li, C; Li, L; Li, Z; Liu, J; Lu, A; Mu, K; Ren, Y; Zhao, H, 2020) |
| "Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung disease." | 1.56 | GLP-1 receptor agonist ameliorates experimental lung fibrosis. ( Diz-Chaves, Y; Fandiño, J; González-Matías, LC; Mallo, F; Toba, L, 2020) |
| "MIA-602 reduced lung inflammation and fibrosis due to bleomycin." | 1.51 | Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin. ( Cai, R; Delcroix, G; Griswold, AJ; Jackson, RM; Lazerson, A; Mirsaeidi, M; Schally, AV; Wangpaichitr, M; Zhang, C, 2019) |
| "Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and high mortality, posing a major threat to human health." | 1.51 | Therapeutic effects of the rhSOD2-Hirudin fusion protein on bleomycin-induced pulmonary fibrosis in mice. ( Breitzig, M; Czachor, A; Huang, L; Huang, M; Lei, S; Li, S; Mo, X; Shen, L; Sun, H; Tian, J; Wang, F; Yi, S; Zheng, Q, 2019) |
| "Damage associated with bleomycin-induced pulmonary fibrosis was alleviated by dermatan sulphate." | 1.51 | Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis. ( Gao, W; Li, W; Xu, J; Xu, S; Yu, Z, 2019) |
| "Idiopathic pulmonary fibrosis is characterized by loss of lung epithelial cells and inexorable progression of fibrosis with no effective and approved treatments." | 1.51 | Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice. ( Chen, M; Dong, M; Gao, Y; Han, L; Jin, F; Li, W; Lin, H; Shi, Y; Zhou, Y; Zuo, W, 2019) |
| "Pulmonary fibrosis is an irreversible lung disorder with predictable decline in lung function leading to respiratory insufficiency." | 1.51 | Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition. ( Bale, S; Godugu, C; Prashanth Goud, M; Pulivendala, G, 2019) |
| "Pulmonary fibrosis is a disease with chronic inflammation and excessive collagen deposition for which there is no effective treatments." | 1.48 | Interleukin-37 Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice. ( Gao, Q; Jiang, W; Li, M; Li, Y; Peng, X; Xu, K; Yuan, X, 2018) |
| "Pulmonary fibrosis is a debilitating disease and is often fatal." | 1.48 | Animal Models of Pulmonary Fibrosis. ( Moore, BB; O'Dwyer, DN, 2018) |
| "Pulmonary fibrosis is a common outcome of various interstitial lung diseases." | 1.48 | Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway. ( He, Y; Jiang, Z; Liu, H; Mei, J; Shen, S; Tang, M, 2018) |
| "Pulmonary fibrosis is a multifaceted disease with high mortality and morbidity, and it is commonly nonresponsive to conventional therapy." | 1.48 | Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats. ( Ahad, A; Ahmad Ansari, M; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Ali, N; Khan, A; Raish, M, 2018) |
| "The exploration of effective treatment for pulmonary fibrosis remains an urgent challenge." | 1.48 | A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice. ( Mao, M; Sun, L; Yan, Z; Zhang, X; Zuo, C, 2018) |
| "Successful construction of a pulmonary fibrosis model was confirmed by H&E and Masson's trichrome staining on the 28th day after exposure to silica suspension." | 1.48 | Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibrosis potentially by attenuating Wnt/β-catenin signaling in rats. ( Chen, S; Du, X; Du, Z; Guan, Y; Lavin, MF; Li, C; Liu, X; Peng, C; Shao, H; Yang, Y; Yeo, AJ; Zhang, E, 2018) |
| "Pulmonary fibrosis is a progressive lung disease that its pathogenic mechanism currently is incompletely understood." | 1.46 | Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary fibrosis mice. ( Dong, J; Han, F; Li, F; Li, H; Liu, X; Luo, M; Qiao, X; Shi, J; Wei, J; Yang, L; Zhang, J, 2017) |
| " In the presence of 50 μM of RA, dose-response for CA shifted to IC50 value of 11." | 1.46 | Rosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts. ( Bahri, S; Ben Ali, R; Jameleddine, S; Mc Entee, K; Mies, F; Mlika, M; Shlyonsky, V, 2017) |
| "Idiopathic pulmonary fibrosis is a severe disease characterized by excessive myofibroblast proliferation, extracellular matrix and fibrils deposition, remodelling of lung parenchyma and pulmonary insufficiency." | 1.46 | HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway. ( Boccalini, G; Calosi, L; Durante, M; Lanzi, C; Lucarini, L; Mannaioni, G; Masini, E; Moroni, F; Pini, A, 2017) |
| "In conclusion, the pulmonary fibrosis induced by silica in rats was significantly reduced by treatment with BMP-7-BMSCs and BMSCs." | 1.46 | Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis. ( An, G; Guo, C; Li, X; Lian, X; Liang, D; Niu, P; Tian, L; Wang, Y; Zhu, Z, 2017) |
| "To understand the mechanisms underlying pulmonary fibrosis and assess potential therapies, mouse models are central to basic and translational research." | 1.46 | Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis. ( Akinyi, TG; Cleveland, ZI; Davidson, CR; Dunn, RS; Guo, J; Hardie, WD; Woods, JC; Zhou, YM, 2017) |
| "Hydroxysafflor yellow A (HSYA) is an active component of Carthamus tinctorius L." | 1.43 | Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice. ( Jin, M; Tan, L; Wang, L; Wu, Y; Zang, B, 2016) |
| "Pulmonary fibrosis is a chronic lung disease characterized by inflammation and collagen deposition, with an estimated mortality rate exceeding 70%." | 1.43 | Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. ( Choi, HG; Hwang, HS; Lee, C; Lee, EH; Lee, ES; Lee, S; Seo, J; Thao, LQ; Youn, YS, 2016) |
| "Pulmonary fibrosis is a progressive lung disorder with high mortality rate and limited successful treatment." | 1.43 | Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9. ( Abuelezz, SA; Hendawy, N; Osman, WM, 2016) |
| "Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis and high mortality rate." | 1.43 | Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of Caveolin-1 and TGF-β1 Signal Pathway. ( Huang, F; Ma, W; Zhan, H; Zhang, C; Zhang, H; Zhao, Z, 2016) |
| "Pulmonary fibrosis is the major limiting factor for the use of bleomycin." | 1.43 | Amelioration of bleomycin-induced lung fibrosis in rats by valproic acid and butyrate: Role of nuclear factor kappa-B, proinflammatory cytokines and oxidative stress. ( Elmaaboud, MAA; Kabel, AM; Omar, MS, 2016) |
| "Successful recovery from lung injury requires the repair and regeneration of alveolar epithelial cells to restore the integrity of gas-exchanging regions within the lung and preserve organ function." | 1.43 | Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. ( Chen, H; Geng, Y; Jiang, D; Kurkciyan, A; Liang, J; Liu, N; Mena, JM; Noble, PW; Stripp, BR; Xie, T; Zhang, Y, 2016) |
| "Idiopathic pulmonary fibrosis is a chronic pulmonary disease that is characterized by formation of scar tissue in lungs." | 1.42 | Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis. ( Abdullah, M; Ho, CC; Koh, RY; Lim, CL; Seow, HF; Uhal, BD; Vidyadaran, S, 2015) |
| "Idiopathic pulmonary fibrosis is the most devastating diffuse fibrosing lung disease of unknown aetiology." | 1.42 | Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis. ( Borensztajn, K; Crestani, B; Daalhuisen, J; Lin, C; Spek, CA; ten Brink, M; van der Poll, T; von der Thüsen, J, 2015) |
| "PRM ameliorated BLM-induced pulmonary fibrosis in rats, with reduction of histopathological scores and collagen deposition, and a decrease in α-smooth muscle actin (α-SMA) and HMGB1 expression." | 1.42 | Protective roles of pulmonary rehabilitation mixture in experimental pulmonary fibrosis in vitro and in vivo. ( Ji, YX; Jiang, WL; Lv, CJ; Zhang, L, 2015) |
| "To examine the effects and possible mechanism of the immunosuppressant agent cyclophosphamide (CP) combined with bone marrow mesenchymal stromal cells (BM-MSCs) on bleomycin induced lung fibrosis in mice." | 1.42 | Cyclophosphamide Combined with Bone Marrow Mesenchymal Stromal Cells Protects against Bleomycin-induced Lung Fibrosis in Mice. ( Li, L; Li, Y; Xiong, J; Xu, J; Ye, Q; Zheng, Y, 2015) |
| "Pulmonary fibrosis is a progressive and lethal disorder." | 1.42 | Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling. ( Guo, K; Ni, S; Pang, L; Qiu, X; Song, Z; Wang, D, 2015) |
| "This drug produces a dose-dependent pulmonary fibrosis (PF) in most patients as well as experimental animals through oxidative injury." | 1.42 | Protective effect of gallic acid against bleomycin-induced pulmonary fibrosis in rats. ( Arzi, A; Ghafourian, M; Hemmati, AA; Mansouri, MT; Nikbakht, J; Rezaie, A, 2015) |
| "Patients with pulmonary fibrosis often have low vitamin D levels, the effects of which are largely unknown." | 1.42 | Preventive effects of vitamin D treatment on bleomycin-induced pulmonary fibrosis. ( Fan, D; Fang, X; Gu, P; Han, F; He, J; Li, S; Liang, A; Yi, X; Yu, X; Yu, Z; Zeng, Y; Zhang, L; Zhang, Z; Zhu, H, 2015) |
| "Pulmonary fibrosis is caused by excessive proliferation and accumulation of stromal cells." | 1.40 | Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis. ( Davidson, C; Edukulla, R; Hardie, WD; Ikegami, M; Madala, SK; Schmidt, S, 2014) |
| "Hydrogen sulfide (H2S) displays vasodilative, anti-oxidative, anti-inflammatory and cytoprotective activities." | 1.40 | Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance. ( Cao, H; Chu, L; Huang, X; Zhai, Y; Zhang, J; Zhang, X; Zhou, X, 2014) |
| "Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with unknown etiology and undefined treatment modality." | 1.40 | CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis. ( Li, Y; Liang, C; Yang, W; Zhang, L, 2014) |
| "Idiopathic pulmonary fibrosis is a progressive and lethal disease, characterized by loss of lung elasticity and alveolar surface area, secondary to alveolar epithelial cell injury, reactive inflammation, proliferation of fibroblasts, and deposition of extracellular matrix." | 1.40 | Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230. ( Accart, N; Beckmann, N; Cannet, C; Dunbar, A; Egger, C; Gérard, C; Jarai, G; Jarman, E; Piaia, A; Schmid, HA; Tigani, B; Vidotto, N, 2014) |
| "Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis." | 1.40 | Ameliorative effect of mepenzolate bromide against pulmonary fibrosis. ( Asano, T; Azuma, A; Kurotsu, S; Mizushima, T; Niino, T; Sugizaki, T; Suzuki, H; Tanaka, K, 2014) |
| "Idiopathic pulmonary fibrosis is a progressive fatal lung disease characterized by excessive collagen deposition, with no effective treatments." | 1.40 | Passion fruit peel extract attenuates bleomycin-induced pulmonary fibrosis in mice. ( Chilakapati, DR; Chilakapati, SR; Manikonda, PK; Serasanambati, M; Watson, RR, 2014) |
| "Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with high mortality and poor prognosis." | 1.40 | Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-κB in mice. ( Chen, ZH; Gou, S; Wang, W; Wang, XC; Xiao, M; Zhu, T, 2014) |
| "Pulmonary fibrosis was induced in Sprague-Dawley rats by BLM (5 mg/kg), killed 14 and 28 days after BLM administration by abdominal aorta exsanguination and removed the lungs." | 1.40 | Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats. ( Fei, GH; Gao, J; Li, LC; Li, P; Qi, LW; Xu, L; Zhao, P, 2014) |
| "Idiopathic pulmonary fibrosis (IPF) is thought to involve inflammatory cells and reactive oxygen species (ROS), such as superoxide anion radical (O2(·-))." | 1.39 | Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression. ( Chuang, VT; Hamasaki, K; Ishima, Y; Kodama, A; Maruyama, T; Mizushima, T; Otagiri, M; Tanaka, K; Tanaka, R; Watanabe, H, 2013) |
| "Currently, there is no satisfactory treatment for pulmonary fibrosis, and effective agents urgently need to be developed." | 1.39 | Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. ( Chen, Y; Gao, Y; Gu, Z; Jiang, X; Lu, J; Zhang, Y, 2013) |
| "Berberine treatments were either provided in preventive or therapeutic mode respectively." | 1.39 | Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study. ( Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G, 2013) |
| "Pulmonary fibrosis is a serious and irreversible lung injury with obscure etiologic mechanisms and no effective treatment to date." | 1.39 | Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis. ( Bai, H; Chen, H; Hai, C; Li, W; Liang, X; Liu, R; Qin, X; Wang, X; Zhang, W; Zhang, X, 2013) |
| "Treatment with methyl palmitate attenuated silica-induced lung inflammation and fibrosis, as it significantly decreased lactate dehydrogenase (LDH) activity and the accumulation of the inflammatory cells in the bronchoalveolar lavage fluid (BALF)." | 1.39 | Protective effects of methyl palmitate against silica-induced pulmonary fibrosis in rats. ( Ammar, el-SM; El-Agamy, DS; Shalaby, AA; Sharawy, MH, 2013) |
| "In conclusion, the pulmonary fibrosis induced by silica in rats was significantly reduced with the therapeutic treatment of BMP-7." | 1.39 | Bone morphogenetic protein-7 inhibits silica-induced pulmonary fibrosis in rats. ( Gao, A; Niu, P; Tian, L; Wang, Y; Yang, G; Zhu, Z, 2013) |
| "LAMR1 mAb can evidently alleviate pulmonary fibrosis induced by bleomycin in rats." | 1.39 | [Monoclonal antibody against laminin receptor 1 inhibits the pulmonary fibrosis induced by bleomycin in rats]. ( Chen, D; Feng, Y; Han, X; Jiang, T; Zhou, M, 2013) |
| "Silicosis is one of the most prevalent occupational lung diseases worldwide." | 1.39 | Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats. ( Gao, A; Niu, P; Tian, L; Wang, Y; Yang, G; Yang, J; Zhu, Z, 2013) |
| "The hydroxyproline (HYP) content was significantly decreased in the AF-1-treated mice." | 1.39 | Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice. ( Chen, Y; Cheng, QM; Feng, DD; Han, JZ; Huang, YH; Li, C; Li, Y; Liu, W; Luo, ZQ; Wan, J; Yue, SJ, 2013) |
| "Pulmonary fibrosis is a progressive and fatal lung disorder with high mortality rate." | 1.39 | Atorvastatin attenuates bleomycin-induced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway. ( Dang, XM; Ma, AQ; Yang, L; Zhu, B, 2013) |
| "1, 25 (OH) 2D3 was shown to reduce pulmonary fibrosis induced by bleomycin in mice, and its mechanisms might be associated with Wnt signaling suppression." | 1.39 | [Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice]. ( Fang, X; Gu, J; Gu, P; Qiu, WZ; Yi, XH; Zeng, Y; Zhang, L; Zhang, SX; Zhang, YD; Zhang, ZM; Zhu, XY, 2013) |
| "Pulmonary fibrosis was induced in C57BL/6 male mice by intratracheal instillation of bleomycin (5 mg." | 1.38 | The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice. ( Chai, Y; Dong, Z; Li, Y; Tai, W; Wang, D; Yang, Y; Zhang, T; Zhong, H; Zou, H, 2012) |
| "Pranlukast attenuates the progression of pulmonary fibrosis in the chronic phase but has no effect on the acute inflammatory response or on the onset of pulmonary fibrosis." | 1.38 | Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice. ( Okunishi, H; Shimbori, C; Shiota, N, 2012) |
| "Cerium compounds have been used as a diesel engine catalyst to lower the mass of diesel exhaust particles, but are emitted as cerium oxide (CeO(2)) nanoparticles in the diesel exhaust." | 1.38 | Induction of pulmonary fibrosis by cerium oxide nanoparticles. ( Barger, M; Castranova, V; Ma, JK; Ma, JY; Mercer, RR; Scabilloni, J; Schwegler-Berry, D, 2012) |
| "Pulmonary fibrosis is one of the most common chronic interstitial lung diseases with high mortality rate after diagnosis and limited successful treatment." | 1.38 | Thymoquinone blocks lung injury and fibrosis by attenuating bleomycin-induced oxidative stress and activation of nuclear factor Kappa-B in rats. ( Awad, AS; El-Bakly, WM; El-Demerdash, E; El-Khouly, D; El-Mesallamy, HO, 2012) |
| "Montelukast treatment also decreased mRNA levels of IL-6, IL-10, IL-13, and TGF-β1, all of which were elevated in fibrotic lungs." | 1.37 | Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice. ( Okunishi, H; Shimbori, C; Shiota, N, 2011) |
| "A mouse model of pulmonary fibrosis was established by tracheal injection of BL (5 mg/kg)." | 1.37 | A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice. ( Fan, X; Gou, L; Liu, N; Liu, Z; Wang, X; Wu, G; Wu, L, 2011) |
| "Montelukast-treated rats showed reduction in collagen deposition by 29% and significant reduction in lung hydroxyproline content by 32%." | 1.37 | Effect of leukotriene receptor antagonists on lung fibrosis in rats. ( Shaker, OG; Sourour, DA, 2011) |
| "Idiopathic pulmonary fibrosis is regarded as a lethal chronic disease accompanied with excessive collagen disposition." | 1.37 | (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a novel readily available and orally active glitazone, attenuates the bleomycin-induced pulmonary fibrosis in vivo. ( Chen, L; Chen, Z; Luo, Y; Ma, L; Ma, Y; Qi, B; Wang, G; Wei, X; Wei, Y; Zheng, H, 2011) |
| "Hydroxyproline content was also significantly lower at 14 weeks in mice treated with taurine (P = 0." | 1.36 | Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice. ( Bouchier-Hayes, DJ; Condron, C; Moriarty, M; Robb, WB; Walsh, TN, 2010) |
| "Pulmonary silicosis is a deadly disease which kills thousands of people every year worldwide." | 1.36 | IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis. ( Chaudhury, BP; Chhabra, JK; Kumar, P; Mishra, V; Pandey, HP; Paul, B; Shukla, M; Tripathi, SS; Verma, M, 2010) |
| "Pravastatin was given through intraperitoneal injection." | 1.36 | Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis. ( Kim, JW; Kim, KH; Kim, SC; Kim, TJ; Kim, YH; Kim, YK; Kwon, SS; Lee, SH; Lee, SY; Rhee, CK; Yoon, HK, 2010) |
| "There is no satisfactory treatment for pulmonary fibrosis, which is characterized by altered control of proliferation of mesenchymal fibroblasts and extracellular matrix production." | 1.35 | Attenuation of bleomycin-induced lung fibrosis by oxymatrine is associated with regulation of fibroblast proliferation and collagen production in primary culture. ( Chen, X; Hu, J; Liao, D; Mo, Z; Sun, R; Yang, Z; Zhong, N, 2008) |
| "Suplatast tosilate is a Th2 cytokine inhibitor that is widely used as an asthma controller in Japan." | 1.35 | Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice. ( Fujitaka, K; Furonaka, M; Haruta, Y; Hattori, N; Ishikawa, N; Kohno, N; Senoo, T; Tanimoto, T; Yokoyama, A, 2009) |
| "Bleomycin-induced pulmonary fibrosis mice were treated intraperitoneally with VEGF receptor tyrosine kinase inhibitor SU5416 at different phases after bleomycin infusion." | 1.35 | VEGFR-2 antagonist SU5416 attenuates bleomycin-induced pulmonary fibrosis in mice. ( Chen, L; Feng, YL; Huang, XY; Li, WC; Li, YP; Liu, DS; Ou, XM; Wang, K; Wang, T; Wang, X; Wen, FQ; Zhang, SF, 2009) |
| "The incidence of pulmonary fibrosis increases with age." | 1.35 | Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice. ( Brigham, KL; Gonzalez, ET; Iyer, SS; Kelly, P; Mac, V; Mora, AL; Reed, A; Rojas, M; Sutliff, RL; Xu, J, 2009) |
| "The results suggested that rapid pulmonary fibrosis could be induced by ALI via LPS three-hits." | 1.35 | Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen. ( Chen, D; Chen, Y; Cui, Y; Du, S; Huang, W; Li, H; Li, Y; Wei, Z; Yang, J; Yang, L; Yao, Z; Zhang, R; Zhang, S; Zhou, J, 2009) |
| "Pulmonary fibrosis is a progressive and lethal lung disease characterized by accumulation of ECM and loss of pulmonary function." | 1.35 | The anti-fibrotic agent SMP-534 attenuates bleomycin-induced pulmonary fibrosis in hamsters. ( Kitoh, M; Nagamine, J; Nagata, R; Nakagawa, T; Ono-Kishino, M; Sugaru, E; Taiji, M; Tokunaga, T; Tsujimura, T, 2009) |
| "Clinical use of GGA for drug-induced pulmonary fibrosis might be considered in the future." | 1.35 | Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model. ( Fujibayashi, T; Hasegawa, Y; Hashimoto, N; Ishiguro, N; Jijiwa, M; Kojima, T, 2009) |
| "The development of pulmonary fibrosis includes inflammatory episodes." | 1.35 | Extracorporeal photopheresis in a rat model of pulmonary fibrosis. ( Boehler, A; Guo, Z; Hofer, M; Rechsteiner, T; Remund, K, 2009) |
| "Sivelestat was given for 13 days intraperitoneally after bleomycin treatments." | 1.35 | Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis. ( Kang, CM; Kim, YK; Moon, HS; Park, SH; Rhee, CK; Song, JS; Yoon, HK, 2009) |
| "The worsening of pulmonary fibrosis was mainly induced by CGS27023A administration in the late phase of bleomycin-induced pulmonary fibrosis development, but not in the early phase." | 1.35 | The role of collagenases in experimental pulmonary fibrosis. ( Fujita, M; Harada, E; Ikegame, S; Inoshima, I; Kuwano, K; Nakanishi, Y; Ouchi, H; Ye, Q, 2008) |
| "Idiopathic pulmonary fibrosis (IPF) is a treatment resistant disease with poor prognosis." | 1.35 | Comparison between conventional and "clinical" assessment of experimental lung fibrosis. ( Ask, K; Farkas, L; Farncombe, T; Froese, A; Gauldie, J; Inman, M; Kolb, MR; Labiris, R; McClelland, GB; Moeller, A, 2008) |
| "The currently accepted approaches to treatment of pulmonary fibrosis are based on the treatment of alveolitis and pulmonary fibrosis, however clinically available anti-inflammatory and antifibrotic agents are not often beneficial." | 1.34 | Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats. ( Hou, J; Li, JX; Zhang, GC; Zhou, XM, 2007) |
| "Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disorder of unknown cause." | 1.34 | Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. ( Brigham, K; Mora, AL; Ritzenthaler, J; Rojas, M; Roman, J; Speck, SH; Stecenko, A; Torres-González, E; Xu, J, 2007) |
| "At days 35 and 63 after idiopathic pulmonary fibrosis/usual interstitial pneumonia fibroblast injection, patchy interstitial fibrosis and increased hydroxyproline were present in the lungs of immunodeficient mice." | 1.34 | Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice. ( Carpenter, K; Flaherty, KR; Hogaboam, CM; Jakubzick, C; Kunkel, SL; Martinez, FJ; Pierce, EM, 2007) |
| "Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in interstitium resulting in respiratory failure associated with inflammation showing mainly neutrophil (PMN) recruitment." | 1.34 | Influence of early neutrophil depletion on MMPs/TIMP-1 balance in bleomycin-induced lung fibrosis. ( Boichot, E; Guénon, I; Lagente, V; Manoury, B; Nénan, S, 2007) |
| "Pulmonary fibrosis was induced in the model group by intranasal instillation of bleomycin 5 mg/kg." | 1.34 | [Experimental study on effect of Huaxian Decoction treating bleomycin-induced pulmonary fibrosis in mice]. ( Bai, W; Wang, CL; Wang, SJ, 2007) |
| " From the second day of intoxication, FZHY recipe treated group orally took FZHY recipe at the dosage of 4." | 1.34 | [Effects of Fuzheng Huayu recipe on MMP-2 activity and type IV collagen expression at fibrotic lung]. ( Cai, ZZ; Liu, CH; Liu, P; Lu, X; Tan, SZ; Ye, WC; Zhang, W, 2007) |
| "Pulmonary fibrosis is a common response to a variety of lung injuries, characterized by fibroblast/myofibroblast expansion and abnormal accumulation of extracellular matrix." | 1.34 | Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin. ( Arreola, JL; Cabrera, S; D'Armiento, J; Gaxiola, M; Jara, P; Pardo, A; Ramírez, R; Richards, T; Selman, M, 2007) |
| "So far, there is no efficient treatment for pulmonary fibrosis." | 1.34 | Effect of intramuscular injection of hepatocyte growth factor plasmid DNA with electroporation on bleomycin-induced lung fibrosis in rats. ( Long, X; Xiong, SD; Xiong, WN; Xu, YJ, 2007) |
| "Pulmonary fibrosis is thought to be closely associated with the T-helper type-2 (Th2) immune response." | 1.34 | Preventive effect of hochu-ekki-to, a Japanese herbal medicine, on bleomycin-induced lung injury in mice. ( Bando, M; Gejyo, F; Moriyama, H; Ohno, S; Sugiyama, Y; Suzuki, E; Tajima, S; Takada, T; Terada, M; Yamasawa, H, 2007) |
| "The current therapeutic approaches for pulmonary fibrosis, which is characterized by fibroblast proliferation and extracellular matrix remodeling, are unsatisfactory." | 1.33 | Effect of Feitai on bleomycin-induced pulmonary fibrosis in rats. ( Cai, Y; Chen, FP; Gong, LK; Huang, CG; Li, XH; Liu, LL; Liu, YZ; Qi, XM; Ren, J; Wang, H; Wu, XF; Zhang, L, 2005) |
| "Idiopathic pulmonary fibrosis is an incurable fibrosing disorder that progresses relentlessly to respiratory failure." | 1.33 | Carbon monoxide suppresses bleomycin-induced lung fibrosis. ( Alber, S; Choi, AM; Fattman, CL; Greenhill, S; Morse, D; Oury, TD; Song, R; Zhou, Z, 2005) |
| "IL-18-/- mice showed much worse lung injuries than wild-type mice, as assessed by the survival rate, histological images, and leukocyte infiltration in the bronchoalveolar lavage fluid and myeloperoxidase activity." | 1.33 | Protection against bleomycin-induced lung injury by IL-18 in mice. ( Adachi, S; Fujita, Y; Kashiwamura, S; Kubota, A; Nakatani-Okuda, A; Okamura, H; Sekiyama, A; Tanizawa, T; Tsuji, Y; Ueda, H, 2005) |
| "CTGF plays a role in pulmonary fibrosis." | 1.33 | [A preliminary study of CTGF in bleomycin-induced mouse pulmonary fibrosis]. ( Lai, GX; Lu, HP; Zhang, L, 2005) |
| "Pulmonary fibrosis is a progressive illness characterized by interstitial fibrosis." | 1.33 | Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma. ( Chung, DH; Chung, JH; Kim, HY; Kim, JH; Kim, S; Park, WS, 2005) |
| "Melatonin has direct and indirect free radical-detoxifying activity." | 1.33 | Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats. ( Erdogan, H; Fadillioglu, E; Iraz, M; Kotuk, M; Kuku, I; Yagmurca, M; Yildirim, Z, 2006) |
| "Hydroxyproline level was significantly higher (13." | 1.33 | Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats. ( Erdogan, H; Ermis, H; Fadillioğlu, E; Iraz, M; Kilic, T; Kotuk, M; Yağmurca, M; Yildirim, Z, 2006) |
| "Experimental pulmonary fibrosis was induced by intra-tracheal administration of BLM in anesthetized mice." | 1.33 | [Inhibition of pulmonary fibrosis by doxycycline: an experiment with mice]. ( Huang, YH; Li, Y; Ouyang, ZG; Shang, Y; Zhen, YS, 2006) |
| "(1)The total cell number in BALF in pulmonary fibrosis groups was statistically significantly higher than that in NC group (all P<0." | 1.33 | [Kinetics and mechanism in bleomycin-induced murine pulmonary fibrosis model]. ( Gao, ZC; Hu, P, 2006) |
| "Pulmonary fibrosis was induced in C57BL/6 mice by direct intratracheal injection of bleomycin." | 1.33 | Immunomodulation of experimental pulmonary fibrosis by intravenous immunoglobulin (IVIG). ( Blank, M; Haj-Yahia, S; Levy, Y; Molina, V; Shoenfeld, Y; Solodeev, I, 2006) |
| "Idiopathic pulmonary fibrosis (IPF) is a progressive chronic disorder characterized by activation of fibroblasts and overproduction of extracellular matrix (ECM)." | 1.33 | Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. ( Choi, AM; Feghali-Bostwick, CA; Ifedigbo, E; Kaminski, N; Kim, HP; Liu, F; Oury, TD; Wang, XM; Xu, X; Zhang, Y; Zhou, Z, 2006) |
| "Chymase inhibitor may be promising for treatment of pulmonary fibrosis in humans." | 1.32 | Involvement of mast cell chymase in bleomycin-induced pulmonary fibrosis in mice. ( Fukami, H; Fukuda, Y; Maruoka, H; Muto, T; Saito, K; Sumida, M; Tanaka, T; Tomimori, Y, 2003) |
| "In BALB/c mice, as in man, progressive pulmonary tuberculosis is accompanied by increasing expression of IL-4." | 1.32 | Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. ( Aguilar, D; Hernandez, ML; Hernandez-Pando, R; Orozco, H; Rook, G, 2004) |
| "The molecular mechanisms of pulmonary fibrosis are poorly understood, although reactive oxygen species are thought to have an important role." | 1.32 | The transcription factor NRF2 protects against pulmonary fibrosis. ( Cho, HY; Kleeberger, SR; Reddy, SP; Yamamoto, M, 2004) |
| "Rats were given one dose of bleomycin in pulmonary fibrosis groups and saline in controls." | 1.32 | Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats. ( Akyol, O; Armutcu, F; Iraz, M; Kaplan, S; Kart, L; Ozen, S; Ozyurt, H; Sogut, S; Temel, I; Yildirim, Z, 2004) |
| "Treatment with pirfenidone significantly reduced the number of these cells compared with the corresponding BL group." | 1.32 | Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis. ( Abe, K; Fujii, T; Hayashi, T; Ishii, H; Kadota, J; Kakugawa, T; Kohno, S; Miyazaki, M; Mukae, H; Oku, H, 2004) |
| "Pulmonary fibrosis was induced in CCR2-/- and wild-type (CCR2+/+) mice by intratracheal instillation of bleomycin." | 1.32 | C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases. ( Kaikita, K; Kawasuji, M; Kobayashi, H; Kuziel, WA; Okuma, T; Takeya, M; Terasaki, Y, 2004) |
| " Successful dosing was confirmed by measuring splenic weight." | 1.31 | The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats. ( Chambers, RC; Egan, JJ; Goldsack, NR; Hasleton, PS; Howell, DC; Laurent, GJ; Marshall, RP; Simler, NR, 2002) |
| "Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium, resulting in impaired lung function and respiratory failure." | 1.31 | Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. ( Bonniaud, P; Galt, T; Gauldie, J; Kelly, MM; Kolb, M; Margetts, PJ; Sime, PJ, 2002) |
| "It has potential of producing pulmonary fibrosis." | 1.31 | The role of sodium cromolyn in treatment of paraquat-induced pulmonary fibrosis in rat. ( Goldasteh, S; Hemmati, AA; Motlagh, ME; Nazari, Z, 2002) |
| "COPD has been reported in workers exposed to particulates, and there is increasing evidence that high levels of ambient particulate pollutants may also be associated with COPD." | 1.31 | Airway wall remodeling induced by occupational mineral dusts and air pollutant particles. ( Churg, A; Wright, JL, 2002) |
| "Treatment with taurine and niacin attenuated the BL-induced increases in proinflammatory cytokines such as IL-1alpha, TNF-alpha, IL-6, and TGF-beta in BALF and lung hydroxyproline content of the mice in BL + TN groups." | 1.31 | Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Pulmonary fibrosis is a disabling consequence of many lung diseases but is difficult to quantify." | 1.31 | Quantitative image analysis of lung connective tissue in murine silicosis. ( Antonini, JM; Davis, GS; Hemenway, DR, 2000) |
| " This study investigated whether irradiation of small lung volumes with high fibrogenic doses affects the dose-response relationship for development of fibrosis in distant parts of the ipsilateral lung of mini-pigs." | 1.31 | Lack of effect of small high-dose volumes on the dose-response relationship for the development of fibrosis in distant parts of the ipsilateral lung in mini-pigs. ( Appold, S; Baumann, M; Geyer, P; Herrmann, T; Knorr, A; Voigtmann, L, 2000) |
| "Thus, fibrosing alveolitis develops after intratracheal bleomycin irrespective of gelatinase B." | 1.31 | Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. ( Betsuyaku, T; Fukuda, Y; Parks, WC; Senior, RM; Shipley, JM, 2000) |
| "Taurine and niacin treatment significantly reduced the numbers of neutrophils, lymphocytes, and macrophages in the BL + TN group and caused significant reductions in BL-induced increases in the lung hydroxyproline content at 14 and 21 days in the BL + TN group." | 1.31 | Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Pulmonary fibrosis is initiated by migration, adhesion, and proliferation of fibroblasts." | 1.31 | Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis. ( Fukuchi, Y; Ienaga, H; Kon, S; Maeda, K; Maeda, M; Okazaki, T; Takahashi, F; Takahashi, K; Uede, T, 2001) |
| "Pulmonary fibrosis is a chronic progressive disease with no effective therapy." | 1.31 | Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin. ( Galt, T; Gauldie, J; Kolb, M; Margetts, PJ; Schmidt, M; Sime, PJ; Xing, Z, 2001) |
| "Batimastat treatment was effective in reducing MMP-2 and MMP-9 activity as well as the tissue inhibitor of metalloproteinase-1 (TIMP-1) level in BAL." | 1.31 | Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat. ( Boichot, E; Caulet-Maugendre, S; Corbel, M; Germain, N; Lagente, V; Molet, S, 2001) |
| "Amiodarone (AM) is an antidysrhythmic agent with a propensity to cause pulmonary toxicity, including potentially fatal fibrosis." | 1.31 | Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis. ( Bennett, BM; Brien, JF; Chung, WH; Massey, TE; Racz, WJ, 2001) |
| "Bleomycin-induced pulmonary fibrosis was studied in mice rendered LT deficient by knockout of the 5-LO gene (KO) and in wild-type (WT) control mice." | 1.31 | Protection from pulmonary fibrosis in leukotriene-deficient mice. ( Bailie, M; Marshall, T; Moore, BB; Peters-Golden, M; Phan, SH; Toews, GB; Wilke, C, 2002) |
| "Paraquat (PQ) is a herbicide that is very toxic to all living organisms." | 1.31 | Captopril inhibits the pulmonary toxicity of paraquat in rats. ( Alagözlü, H; Candan, F, 2001) |
| "Pulmonary fibrosis is a progressive and largely untreatable group of disorders that affects up to 100,000 people on any given day in the United States." | 1.31 | Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. ( Allard, J; Ben-Dor, A; DeLustro, B; Eugui, E; Heller, RA; Kaminski, N; Kim, Y; Lollini, L; Morris, D; Pardo, A; Selman, M; Sheppard, D; Yakhini, Z; Zuo, F, 2002) |
| "Pulmonary fibrosis is an interstitial disorder of the lung parenchyma whose mechanism is poorly understood." | 1.31 | A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis. ( Ishii, S; Kita, Y; Nagase, T; Ohga, E; Ouchi, Y; Shimizu, T; Uozumi, N; Yamamoto, H, 2002) |
| " Male F344 rats were intratracheally dosed with AD (6." | 1.31 | Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy. ( Antonini, JM; Hubbs, AF; Reasor, MJ; Roberts, JR; Taylor, MD, 2002) |
| "To elucidate the pathophysiology of pulmonary fibrosis, we investigated the involvement of p38 mitogen-activated protein kinase (MAPK), which is one of the major signal transduction pathways of proinflammatory cytokines, in a murine model of bleomycin-induced lung fibrosis." | 1.31 | A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis. ( Arai, T; Fujiwara, H; Goya, S; Hayashi, S; Kida, H; Matsuoka, H; Mori, M; Morishita, H; Osaki, T; Tachibana, I, 2002) |
| "This new and versatile model of pulmonary fibrosis can be used to study such therapies." | 1.30 | Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. ( Csaky, KG; Gauldie, J; Graham, FL; Sime, PJ; Xing, Z, 1997) |
| "The hydroxyproline (Hyp) content was measured in the pulmonary tissue after digestion with HCl." | 1.30 | Kinetic alterations of angiotensin-II and nitric oxide in radiation pulmonary fibrosis. ( Cui, X; Shi, Z; Song, L; Wang, D; Yang, H, 1998) |
| "Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes." | 1.30 | The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998) |
| "Amiodarone (AM) is a potent antidysrhythmic agent that is limited in clinical use by its adverse effects, including potentially life-threatening AM-induced pulmonary toxicity (AIPT)." | 1.30 | Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters. ( Bray, TM; Brien, JF; Card, JW; Leeder, RG; Massey, TE; Racz, WJ, 1999) |
| "Tetrandrine (TT) has been shown to inhibit stimulant-induced macrophage respiratory burst and effectively reduce silica-induced lung injury." | 1.30 | Use of tetrandrine to differentiate between mechanisms involved in silica-versus bleomycin-induced fibrosis. ( Barger, MW; Castranova, V; Hubbs, AF; Ma, JK; Ma, JY; Weber, SL, 1999) |
| "Lucifer Yellow has been shown an ideal fluorescent stain to examine the connective tissue matrix components of embedded lung tissue with LSCM." | 1.30 | Application of laser scanning confocal microscopy in the analysis of particle-induced pulmonary fibrosis. ( Antonini, JM; Blake, TL; Charron, TG; Lai, J; Roberts, JR; Rogers, RA, 1999) |
| "Hydroxyproline (HP) was assayed biochemically, and the amount of HP in the alveolar wall for each rabbit was calculated using the assayed values of HP and the ratio of histologic collagen points in the alveolar wall to those in the lung tissue by a point count method." | 1.29 | Suppressive effect of anti-alpha 1-antichymotrypsin serum on pulmonary fibrosis induced by phorbol myristate acetate in vivo. ( Imakon, Y; Matsubara, H; Nagareda, T; Nishizawa, Y; Noro, A; Shiomi, H; Tanaka, A; Terada, N, 1995) |
| "Pulmonary fibrosis was assessed biochemically by measuring pulmonary elastin and hydroxyproline content." | 1.29 | Effects of the 21-aminosteroid, U74389F, on bleomycin-induced pulmonary fibrosis in rats. ( Frank, L; McLaughlin, GE, 1994) |
| "Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an overexuberant lung collagen reactivity followed by deposition of highly cross-linked mature collagen fibrils resistant to enzymatic degradation." | 1.29 | Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. ( Blaisdell, R; Giri, SN; Hyde, DM; Rucker, RB; Wang, Q, 1994) |
| "Lung hydroxyproline content was determined 28 d after exposure and lung histopathology was characterized on d 28 and 90 after exposure." | 1.29 | Alveolar macrophage cytokine and growth factor production in a rat model of crocidolite-induced pulmonary inflammation and fibrosis. ( Driscoll, KE; Higgins, J; Maurer, JK; Poynter, J, 1995) |
| "Lung hydroxyproline was also reduced in asbestos-exposed SCID mice after T lymphocyte reconstitution and, conversely, increased in T cell-depleted Balb/c mice." | 1.29 | A protective role for T lymphocytes in asbestos-induced pulmonary inflammation and collagen deposition. ( Blazka, ME; Corsini, E; Craig, WA; Luster, MI; Mahler, J; Rosenthal, GJ, 1994) |
| "Pulmonary fibrosis was first detected at 15 days and was progressive with time elapsed after trichloroethylene exposure." | 1.29 | Trichloroethylene induces pulmonary fibrosis in mice. ( Forkert, L; Forkert, PG, 1994) |
| "Amiodarone is an effective antidysrhythmic agent, restricted in use by the development of pulmonary toxicity." | 1.29 | Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration. ( Brien, JF; Evans, CD; Leeder, RG; Massey, TE, 1994) |
| "This unique animal model of progressive pulmonary fibrosis resembles the final stages of human idiopathic pulmonary fibrosis and should facilitate studying underlying mechanisms and potential therapy of progressive pulmonary fibrosis." | 1.29 | A new model of progressive pulmonary fibrosis in rats. ( Gelzleichter, TR; Last, JA; Pinkerton, KE; Walker, RM; Witschi, H, 1993) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 1.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "This suggests an early onset of pulmonary fibrosis." | 1.29 | Biochemical and morphological characterization of carbon tetrachloride-induced lung fibrosis in rats. ( Ala-Kokko, L; Anttila, S; Ferrans, VJ; Pääkkö, P; Peura, R; Ryhänen, L; Sormunen, R, 1996) |
| "Pulmonary fibrosis was elicited in mice or rats by the intratracheal instillation of bleomycin or silica." | 1.29 | Heparin attenuates bleomycin but not silica-induced pulmonary fibrosis in mice: possible relationship with involvement of myofibroblasts in bleomycin, and fibroblasts in silica-induced fibrosis. ( Guo, J; Piguet, PF; Van, GY, 1996) |
| "Since pulmonary fibrosis develops even in nude athymic mice, T cells do not seem to play a primary part in fibrogenic response but they regulate, at least to some extent, the response of inflammatory cells and fibrogenesis of the lung." | 1.29 | T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice. ( Horiuchi, T; Ito, K; Kuwabara, M; Ohta, K; Shiga, J; Suzuki, N; Takizawa, H; Ueda, T, 1996) |
| "A model of pulmonary fibrosis in rat has been developed using intratracheal administration of bleomycin (BLM) A5 (5mg/kg)." | 1.28 | [The role of oxygen radicals in bleomycin-induced pulmonary fibrosis]. ( Wang, XZ, 1992) |
| "Niacin was used in the present study to investigate changes in some biochemical parameters and enzymes involved in the development of BL-induced lung fibrosis in the hamster." | 1.28 | Effects of niacin on bleomycin-induced increases in myeloperoxidase, prolyl hydroxylase, and superoxide dismutase activities and collagen accumulation in the lungs of hamsters. ( Giri, SN; O'Neill, CA, 1992) |
| "Silica-induced pulmonary fibrosis usually follows exposure to increased levels of this particulate and its retention in interstitial macrophages of the lung." | 1.28 | Instillation of chemotactic factor to silica-injected lungs lowers interstitial particle content and reduces pulmonary fibrosis. ( Adamson, IY; Bowden, DH; Prieditis, H, 1992) |
| "The development of bleomycin-induced pulmonary fibrosis in rats was studied over a period of 30 days after an intratracheal instillation of bleomycin." | 1.28 | Alveolar accumulation of fibronectin and hyaluronan precedes bleomycin-induced pulmonary fibrosis in the rat. ( Bjermer, L; Hällgren, R; Hernnäs, J; Malmström, A; Nettelbladt, O; Särnstrand, B, 1992) |
| "Lung hydroxyproline concentration was characterized as a marker of lung collagen." | 1.28 | Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis. ( Asquith, T; Driscoll, KE; Higgins, J; Maurer, JK; Miller, NS; Poynter, J, 1992) |
| "Hydroxyproline levels in treated animals did not differ significantly from control levels throughout the study." | 1.28 | Repeated episodes of C5a-induced neutrophil influx do not result in pulmonary fibrosis. ( Giri, SN; Harris, JA; Hyde, DM; Stovall, MY; Wang, QJ, 1991) |
| "Hydroxyproline concentration was determined by Stegemann method using the modification of Hurych and Chvapil (2)." | 1.28 | [Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue]. ( Ociepiński, M; Szaflarska-Stojko, E; Zyłka-Włoszczyk, M, 1991) |
| "Interstitial pulmonary fibrosis induced by bleomycin (BL) involves the production of reactive oxygen species and the impairment of repair of damaged epithelial cells." | 1.28 | Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. ( Giri, SN; Hyde, DM; Li, C; Wang, QJ, 1991) |
| "In the present paper, we evidenced that pulmonary fibrosis could be induced in genetically mast cell-deficient WBB6F1-W/Wv mice as well as WBB6F1-(+/+) mice having mast cells normally by the treatment with bleomycin (BLM, 5 mg/kg, i." | 1.28 | Bleomycin-induced pulmonary fibrosis in genetically mast cell-deficient WBB6F1-W/Wv mice and mechanism of the suppressive effect of tranilast, an antiallergic drug inhibiting mediator release from mast cells, on fibrosis. ( Kawada, K; Koda, A; Mori, H; Sakamoto, O; Uesugi, Y; Zhang, P, 1991) |
| "A model of pulmonary fibrosis caused by a single intratracheal injection 0." | 1.28 | [A study on the inhibition effect of tetrandrine on the pingyangmycinum induced pulmonary fibrosis]. ( Jin, H, 1991) |
| " To determine if lung injury, inflammation, and asbestosis could be inhibited in vivo in a rapid-onset, inhalation model of disease, a novel method of chronic administration of antioxidant enzymes was developed." | 1.28 | Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis. ( Adler, KB; Doherty, J; Hemenway, D; Hill, S; Marsh, JP; Mickey, R; Mossman, BT; Petruska, J; Sesko, A; Shatos, MA, 1990) |
| "Intratracheal bleomycin induces pulmonary fibrosis in experimental animals, but the mechanisms involved are poorly understood." | 1.28 | Dietary fish oil inhibits bleomycin-induced pulmonary fibrosis in the rat. ( Chandler, DB; Fulmer, JD; Grizzle, WE; Kennedy, JI; Wert, MB, 1989) |
| " Mice injected subcutaneously with bleomycin A2 developed pulmonary fibrosis, while animals treated with equivalent doses of desamido-bleomycin A2 did not, indicating that this metabolite is not as toxic to the lungs as is the parent compound." | 1.27 | Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity. ( Humphreys, CJ; Lazo, JS, 1983) |
| "A severe interstitial pneumonitis was evident histologically 15 days after BHT-treatment." | 1.27 | Enhanced acute lung damage following corticosteroid treatment. ( Kehrer, JP; Klein-Szanto, AJ; Pearlman, R; Rosner, MH; Sorensen, EM, 1984) |
| " These biochemical changes may account, at least in part, for the mitigation of the toxic effects of hyperoxia, as shown by the delayed appearance of arterial hypoxemia, and the 50% increase in survival time when bleomycin injected rabbits were exposed to 100% O2 35 days postinjection." | 1.27 | Modification of pulmonary oxygen toxicity by bleomycin treatment. ( Goldinger, JM; Harper, WV; Matalon, S; Nickerson, PA; Olszowka, J, 1985) |
| "Interstitial pulmonary fibrosis is characterized by an abnormal accumulation of fibroblasts with a resultant increase in lung collagen content." | 1.27 | The effect of cyclosporin A on pulmonary fibrosis induced by butylated hydroxytoluene, bleomycin and beryllium sulfate. ( Lindenschmidt, RC; Sendelbach, LE; Witschi, HP, 1985) |
| "Bleomycin (BLM) produces pulmonary fibrosis in mice when given as a single intratracheal injection, a single i." | 1.27 | High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis. ( Harrison, JH; Lazo, JS, 1987) |
| "Lung hydroxyproline concentration was not increased after bleomycin plus oxygen as compared with bleomycin alone." | 1.27 | Absence of an additional fibrotic response caused by oxygen in the lungs of rats after the intratracheal administration of bleomycin. ( Blom-Muilwijk, MC; Konings, AW; Sleyfer, DT; Veninga, TS; Vriesendorp, R, 1988) |
| "Two agents that produce pulmonary fibrosis were selected for this study." | 1.27 | The combination of ozone and silica on the development of pulmonary fibrosis. ( Drew, RT; Osheroff, MR; Shiotsuka, RN; Yermakoff, JK, 1986) |
| "Animals were primed for contact hypersensitivity responses by skin painting with trinitrophenol (TNP), but instead of challenging with the antigen on the skin, animals were challenged with a single intratracheally administered dose of the immunizing hapten." | 1.27 | Pulmonary interstitial fibrosis induced in hapten-immune hamsters. ( Fisch, H; Lipscomb, MF; Stein-Streilein, J; Whitney, PL, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (17.39) | 18.7374 |
| 1990's | 103 (19.47) | 18.2507 |
| 2000's | 157 (29.68) | 29.6817 |
| 2010's | 159 (30.06) | 24.3611 |
| 2020's | 18 (3.40) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, CF | 1 |
| Wilson, CL | 1 |
| Chow, YH | 1 |
| Liles, WC | 1 |
| Gharib, SA | 1 |
| Altemeier, WA | 1 |
| Schnapp, LM | 1 |
| Yang, H | 3 |
| Wang, L | 6 |
| Yang, M | 1 |
| Hu, J | 2 |
| Zhang, E | 2 |
| Peng, L | 1 |
| Piao, C | 1 |
| Zhuang, C | 1 |
| Ko, MK | 1 |
| Hwang, DW | 1 |
| Lee, M | 1 |
| Chen, Y | 8 |
| Song, M | 1 |
| Li, Z | 5 |
| Hou, L | 1 |
| Zhang, H | 4 |
| Zhang, Z | 4 |
| Hu, H | 3 |
| Jiang, X | 2 |
| Yang, J | 4 |
| Zou, X | 1 |
| Pang, J | 1 |
| Zhang, T | 3 |
| Yang, P | 1 |
| Wang, J | 5 |
| Wang, C | 1 |
| Tang, Q | 1 |
| Xing, C | 1 |
| Li, M | 3 |
| Jia, Q | 1 |
| Bo, C | 1 |
| Nassar, SZ | 1 |
| Abdelmonsif, DA | 1 |
| Ali, RG | 1 |
| Badae, NM | 1 |
| Suzuka, T | 1 |
| Kotani, T | 1 |
| Saito, T | 1 |
| Matsuda, S | 1 |
| Sato, T | 1 |
| Takeuchi, T | 1 |
| Yang, S | 1 |
| Feng, X | 1 |
| Wang, Y | 12 |
| Qu, Y | 1 |
| Xing, L | 1 |
| Wang, H | 3 |
| Zhang, Y | 5 |
| Li, X | 8 |
| Asker, ME | 1 |
| Abdelmeged, AA | 1 |
| Shaheen, MA | 1 |
| Eissa, RG | 1 |
| Liu, Y | 4 |
| Tang, A | 1 |
| Liu, M | 1 |
| Xu, C | 1 |
| Cao, F | 1 |
| Yang, C | 2 |
| Zhang, C | 3 |
| Cai, R | 1 |
| Lazerson, A | 1 |
| Delcroix, G | 1 |
| Wangpaichitr, M | 1 |
| Mirsaeidi, M | 1 |
| Griswold, AJ | 1 |
| Schally, AV | 1 |
| Jackson, RM | 2 |
| Horowitz, JC | 3 |
| Tschumperlin, DJ | 1 |
| Kim, KK | 3 |
| Osterholzer, JJ | 1 |
| Subbotina, N | 2 |
| Ajayi, IO | 1 |
| Teitz-Tennenbaum, S | 1 |
| Virk, A | 1 |
| Dotson, M | 1 |
| Liu, F | 3 |
| Sicard, D | 1 |
| Jia, S | 1 |
| Sisson, TH | 2 |
| Mirzaee, S | 1 |
| Mansouri, E | 2 |
| Shirani, M | 1 |
| Zeinvand-Lorestani, M | 1 |
| Khodayar, MJ | 2 |
| Lu, Y | 3 |
| Zhao, C | 3 |
| Lei, L | 2 |
| Tao, Z | 2 |
| Zheng, L | 1 |
| Wen, J | 1 |
| Bai, L | 1 |
| Li, A | 1 |
| Gong, C | 1 |
| Ning, X | 1 |
| Wang, Z | 1 |
| Zhang, R | 2 |
| Xu, L | 6 |
| An, X | 1 |
| Sui, X | 1 |
| Lin, S | 1 |
| Zhao, H | 2 |
| Li, C | 8 |
| Li, L | 5 |
| Liu, J | 7 |
| Gao, Y | 3 |
| Mu, K | 1 |
| Chen, D | 3 |
| Lu, A | 1 |
| Ren, Y | 1 |
| Qu, SJ | 1 |
| Zhao, L | 4 |
| Song, ZZ | 1 |
| Shen, WP | 1 |
| Ju, P | 1 |
| Li, YM | 1 |
| Fandiño, J | 1 |
| Toba, L | 1 |
| González-Matías, LC | 1 |
| Diz-Chaves, Y | 1 |
| Mallo, F | 1 |
| Li, RF | 1 |
| Chen, XY | 2 |
| Xu, Y | 1 |
| Feng, FC | 1 |
| He, HL | 1 |
| Zhou, XM | 4 |
| Chung, EJ | 2 |
| Kwon, S | 1 |
| Reedy, JL | 1 |
| White, AO | 1 |
| Song, JS | 2 |
| Hwang, I | 1 |
| Chung, JY | 1 |
| Ylaya, K | 1 |
| Hewitt, SM | 1 |
| Citrin, DE | 1 |
| Dong, WW | 1 |
| Zhang, YQ | 1 |
| Zhu, XY | 2 |
| Mao, YF | 1 |
| Sun, XJ | 2 |
| Liu, YJ | 1 |
| Jiang, L | 3 |
| Li, F | 1 |
| Han, F | 2 |
| Li, H | 4 |
| Zhang, J | 3 |
| Qiao, X | 1 |
| Shi, J | 1 |
| Yang, L | 5 |
| Dong, J | 3 |
| Luo, M | 1 |
| Wei, J | 1 |
| Liu, X | 2 |
| Yu, Y | 1 |
| Li, W | 5 |
| Liu, B | 1 |
| Jiao, X | 1 |
| Song, X | 2 |
| Lv, C | 2 |
| Qin, S | 1 |
| Kuang, J | 1 |
| Wei, XL | 1 |
| Xie, M | 1 |
| Bahri, S | 1 |
| Mies, F | 1 |
| Ben Ali, R | 1 |
| Mlika, M | 1 |
| Jameleddine, S | 1 |
| Mc Entee, K | 1 |
| Shlyonsky, V | 1 |
| Rasooli, R | 2 |
| Pourgholamhosein, F | 1 |
| Kamali, Y | 1 |
| Nabipour, F | 1 |
| Mandegary, A | 2 |
| Du, S | 2 |
| Li, S | 6 |
| Weng, D | 2 |
| Chen, J | 8 |
| Wang, X | 11 |
| Xu, K | 2 |
| Yang, XY | 1 |
| Zeng, Q | 1 |
| Wang, FS | 1 |
| Pourgholamhossein, F | 1 |
| Pournamdari, M | 1 |
| Pourgholi, L | 1 |
| Samareh-Fekri, M | 1 |
| Ghazi-Khansari, M | 1 |
| Iranpour, M | 1 |
| Poursalehi, HR | 1 |
| Heidari, MR | 1 |
| Zhou, F | 1 |
| Mei, H | 1 |
| Ma, H | 1 |
| Shi, L | 1 |
| Huang, A | 1 |
| Lin, Z | 1 |
| Wu, G | 2 |
| Wermuth, PJ | 1 |
| Jimenez, SA | 1 |
| Gao, J | 7 |
| Feng, S | 1 |
| Li, Y | 10 |
| Hyo-Seok, S | 1 |
| Hyun, JL | 1 |
| Choong, JL | 1 |
| Gao, Q | 1 |
| Peng, X | 1 |
| Yuan, X | 1 |
| Jiang, W | 1 |
| Karkale, S | 1 |
| Khurana, A | 1 |
| Saifi, MA | 1 |
| Godugu, C | 2 |
| Talla, V | 1 |
| O'Dwyer, DN | 1 |
| Moore, BB | 2 |
| Lu, J | 2 |
| Wang, B | 2 |
| Zhang, X | 7 |
| Huang, Q | 1 |
| Yuan, J | 1 |
| Hao, H | 4 |
| Chen, X | 5 |
| Zhi, J | 1 |
| Chu, H | 1 |
| Kim, HY | 2 |
| Kim, MS | 1 |
| Kim, SH | 1 |
| Joen, D | 1 |
| Lee, K | 1 |
| Liu, H | 2 |
| He, Y | 1 |
| Jiang, Z | 2 |
| Shen, S | 1 |
| Mei, J | 1 |
| Tang, M | 1 |
| Raish, M | 1 |
| Ahmad, A | 1 |
| Ahmad Ansari, M | 1 |
| Ahad, A | 1 |
| Al-Jenoobi, FI | 1 |
| Al-Mohizea, AM | 1 |
| Khan, A | 1 |
| Ali, N | 1 |
| Sun, L | 1 |
| Mao, M | 1 |
| Yan, Z | 1 |
| Zuo, C | 1 |
| Yang, Y | 2 |
| Chen, S | 1 |
| Peng, C | 1 |
| Lavin, MF | 1 |
| Yeo, AJ | 1 |
| Guan, Y | 1 |
| Du, X | 1 |
| Du, Z | 1 |
| Shao, H | 1 |
| You, L | 1 |
| Zhao, M | 1 |
| Tian, M | 1 |
| Chang, X | 1 |
| Zhang, Q | 1 |
| Sun, Y | 2 |
| Shen, L | 1 |
| Lei, S | 1 |
| Huang, L | 1 |
| Yi, S | 1 |
| Breitzig, M | 1 |
| Huang, M | 1 |
| Mo, X | 3 |
| Sun, H | 2 |
| Zheng, Q | 1 |
| Tian, J | 1 |
| Czachor, A | 1 |
| Wang, F | 2 |
| Shariati, S | 1 |
| Kalantar, H | 1 |
| Pashmforoosh, M | 1 |
| Marts, LT | 1 |
| Guidot, DM | 2 |
| Sueblinvong, V | 2 |
| Xu, J | 5 |
| Xu, S | 1 |
| Gao, W | 1 |
| Yu, Z | 2 |
| Shi, Y | 2 |
| Dong, M | 1 |
| Zhou, Y | 1 |
| Han, L | 1 |
| Chen, M | 1 |
| Lin, H | 1 |
| Zuo, W | 1 |
| Jin, F | 1 |
| Prashanth Goud, M | 1 |
| Bale, S | 1 |
| Pulivendala, G | 1 |
| Tanaka, R | 1 |
| Watanabe, H | 1 |
| Kodama, A | 1 |
| Chuang, VT | 1 |
| Ishima, Y | 1 |
| Hamasaki, K | 1 |
| Tanaka, K | 2 |
| Mizushima, T | 3 |
| Otagiri, M | 1 |
| Maruyama, T | 1 |
| Qiu, X | 2 |
| Zhang, F | 1 |
| Jin, H | 5 |
| Fu, J | 1 |
| Xia, Z | 2 |
| Wang, M | 1 |
| Liu, W | 3 |
| Zhang, L | 7 |
| Gu, Z | 1 |
| Chitra, P | 1 |
| Saiprasad, G | 1 |
| Manikandan, R | 1 |
| Sudhandiran, G | 1 |
| Schroll, S | 1 |
| Lange, TJ | 1 |
| Arzt, M | 1 |
| Sebah, D | 1 |
| Nowrotek, A | 1 |
| Lehmann, H | 1 |
| Wensel, R | 1 |
| Pfeifer, M | 1 |
| Blumberg, FC | 1 |
| Liu, R | 2 |
| Chen, H | 2 |
| Bai, H | 1 |
| Zhang, W | 3 |
| Qin, X | 1 |
| Liang, X | 1 |
| Hai, C | 1 |
| Zeng, T | 1 |
| Zhao, X | 2 |
| Xiea, K | 1 |
| Bi, Y | 1 |
| Zhong, Z | 1 |
| Sharawy, MH | 2 |
| El-Agamy, DS | 2 |
| Shalaby, AA | 1 |
| Ammar, el-SM | 1 |
| Yang, G | 2 |
| Zhu, Z | 3 |
| Gao, A | 2 |
| Niu, P | 3 |
| Tian, L | 4 |
| Yang, D | 1 |
| Zhu, S | 2 |
| Gu, J | 2 |
| Ding, F | 1 |
| Bian, W | 1 |
| Rong, Z | 1 |
| Shen, C | 1 |
| Jiang, T | 1 |
| Feng, Y | 1 |
| Zhou, M | 1 |
| Han, X | 1 |
| Yin, G | 1 |
| Jiang, H | 1 |
| Niu, CH | 1 |
| Liu, JD | 1 |
| Wang, JL | 1 |
| Xiao, JH | 1 |
| Verma, R | 1 |
| Brahmankar, M | 1 |
| Kushwah, L | 1 |
| Suresh, B | 1 |
| Kerchberger, VE | 1 |
| Saghafi, R | 1 |
| Mills, ST | 1 |
| Fan, X | 2 |
| Wan, J | 1 |
| Han, JZ | 1 |
| Feng, DD | 1 |
| Yue, SJ | 1 |
| Huang, YH | 2 |
| Cheng, QM | 1 |
| Luo, ZQ | 1 |
| Malekinejad, H | 1 |
| Mehrabi, M | 1 |
| Khoramjouy, M | 1 |
| Rezaei-Golmisheh, A | 1 |
| Madala, SK | 1 |
| Edukulla, R | 1 |
| Schmidt, S | 1 |
| Davidson, C | 1 |
| Ikegami, M | 1 |
| Hardie, WD | 2 |
| Cao, H | 1 |
| Zhou, X | 3 |
| Huang, X | 1 |
| Zhai, Y | 1 |
| Chu, L | 1 |
| Liang, C | 1 |
| Yang, W | 1 |
| Zhu, B | 1 |
| Ma, AQ | 1 |
| Dang, XM | 1 |
| Kach, J | 1 |
| Sandbo, N | 1 |
| La, J | 1 |
| Denner, D | 1 |
| Reed, EB | 1 |
| Akimova, O | 1 |
| Koltsova, S | 1 |
| Orlov, SN | 1 |
| Dulin, NO | 1 |
| Ammar, EM | 1 |
| Zhang, ZM | 1 |
| Gu, P | 2 |
| Yi, XH | 1 |
| Fang, X | 2 |
| Zeng, Y | 2 |
| Zhang, SX | 1 |
| Zhang, YD | 1 |
| Qiu, WZ | 1 |
| Velikoff, M | 1 |
| Canalis, E | 1 |
| Liu, T | 2 |
| Yu, H | 2 |
| Ullenbruch, M | 2 |
| Ito, T | 1 |
| Wu, Z | 1 |
| Phan, SH | 8 |
| Lee, SH | 2 |
| Lee, EJ | 1 |
| Lee, SY | 3 |
| Kim, JH | 3 |
| Shim, JJ | 1 |
| Shin, C | 1 |
| In, KH | 1 |
| Kang, KH | 1 |
| Uhm, CS | 1 |
| Kim, HK | 1 |
| Yang, KS | 1 |
| Park, S | 1 |
| Kim, HS | 1 |
| Kim, YM | 1 |
| Yoo, TJ | 1 |
| Egger, C | 1 |
| Gérard, C | 1 |
| Vidotto, N | 1 |
| Accart, N | 1 |
| Cannet, C | 1 |
| Dunbar, A | 1 |
| Tigani, B | 1 |
| Piaia, A | 1 |
| Jarai, G | 1 |
| Jarman, E | 1 |
| Schmid, HA | 1 |
| Beckmann, N | 1 |
| You, H | 1 |
| Wei, L | 1 |
| Sun, WL | 1 |
| Yang, ZL | 1 |
| Zheng, K | 1 |
| Zhang, WJ | 1 |
| Yao, Y | 1 |
| Zhou, C | 1 |
| Chu, D | 1 |
| Kurotsu, S | 1 |
| Niino, T | 1 |
| Asano, T | 1 |
| Sugizaki, T | 1 |
| Azuma, A | 4 |
| Suzuki, H | 1 |
| Shkurupiy, VA | 1 |
| Kim, LB | 1 |
| Potapova, OV | 1 |
| Cherdantseva, LA | 1 |
| Putyatina, AN | 1 |
| Nikonova, IK | 1 |
| Parra, ER | 1 |
| Pincelli, MS | 1 |
| Teodoro, WR | 1 |
| Velosa, AP | 1 |
| Martins, V | 1 |
| Rangel, MP | 1 |
| Barbas-Filho, JV | 1 |
| Capelozzi, VL | 1 |
| Chilakapati, SR | 1 |
| Serasanambati, M | 1 |
| Manikonda, PK | 1 |
| Chilakapati, DR | 1 |
| Watson, RR | 1 |
| Pei, H | 1 |
| Fan, D | 2 |
| Zhang, M | 6 |
| Chen, B | 2 |
| Zhou, R | 1 |
| Fu, Y | 1 |
| Rong, M | 1 |
| Zhu, P | 1 |
| Chen, L | 4 |
| Fan, C | 1 |
| Li, J | 5 |
| Fu, X | 1 |
| Gou, S | 1 |
| Zhu, T | 1 |
| Wang, W | 2 |
| Xiao, M | 1 |
| Wang, XC | 1 |
| Chen, ZH | 1 |
| Gao, SY | 1 |
| Li, YJ | 2 |
| Liu, WL | 1 |
| Wang, PY | 1 |
| Pang, M | 1 |
| Xie, SY | 1 |
| Lv, CJ | 2 |
| Li, LC | 2 |
| Zhao, P | 4 |
| Qi, LW | 1 |
| Li, P | 3 |
| Fei, GH | 1 |
| Guo, F | 1 |
| Sun, YB | 1 |
| Su, L | 1 |
| Liu, ZF | 1 |
| Hu, XT | 1 |
| Cui, K | 1 |
| Kou, JQ | 1 |
| Gu, JH | 1 |
| Han, R | 1 |
| Wang, G | 2 |
| Zhen, X | 1 |
| Qin, ZH | 1 |
| He, ZY | 1 |
| Zhong, XN | 1 |
| Koh, RY | 1 |
| Lim, CL | 1 |
| Uhal, BD | 1 |
| Abdullah, M | 1 |
| Vidyadaran, S | 1 |
| Ho, CC | 1 |
| Seow, HF | 1 |
| Li, D | 2 |
| Deng, Z | 1 |
| Qi, L | 2 |
| Lin, C | 1 |
| von der Thüsen, J | 1 |
| Daalhuisen, J | 1 |
| ten Brink, M | 1 |
| Crestani, B | 1 |
| van der Poll, T | 1 |
| Borensztajn, K | 1 |
| Spek, CA | 1 |
| Ji, YX | 1 |
| Jiang, WL | 1 |
| Xiong, J | 1 |
| Zheng, Y | 2 |
| Ye, Q | 3 |
| Wang, YY | 1 |
| Zhang, CY | 1 |
| Ma, YQ | 1 |
| He, ZX | 1 |
| Zhe, H | 1 |
| Zhou, SF | 1 |
| Li, DL | 1 |
| Mo, XT | 1 |
| Cui, WH | 1 |
| Zhou, WC | 1 |
| Nishimoto, T | 1 |
| Mlakar, L | 1 |
| Takihara, T | 1 |
| Feghali-Bostwick, C | 1 |
| Ni, S | 1 |
| Wang, D | 4 |
| Pang, L | 1 |
| Song, Z | 1 |
| Guo, K | 1 |
| Song, Y | 1 |
| Guo, H | 1 |
| Zhang, G | 1 |
| You, XY | 1 |
| Xue, Q | 1 |
| Fang, Y | 1 |
| Liu, Q | 1 |
| Zhang, CF | 1 |
| Xu, XH | 1 |
| Cui, W | 1 |
| Zhou, W | 2 |
| Shichino, S | 1 |
| Abe, J | 1 |
| Ueha, S | 1 |
| Otsuji, M | 1 |
| Tsukui, T | 1 |
| Kosugi-Kanaya, M | 1 |
| Shand, FH | 1 |
| Hashimoto, S | 1 |
| Suzuki, HI | 1 |
| Morikawa, T | 1 |
| Inagaki, Y | 1 |
| Matsushima, K | 1 |
| Nikbakht, J | 1 |
| Hemmati, AA | 5 |
| Arzi, A | 2 |
| Mansouri, MT | 1 |
| Rezaie, A | 2 |
| Ghafourian, M | 2 |
| Kim, SW | 1 |
| Park, CK | 1 |
| Kim, TJ | 2 |
| Kim, YK | 3 |
| Kwon, SS | 2 |
| Rhee, CK | 3 |
| Yoon, HK | 3 |
| Cai, Y | 2 |
| Kimura, S | 1 |
| Yu, X | 1 |
| Liang, A | 1 |
| He, J | 1 |
| Zhu, H | 1 |
| Yi, X | 1 |
| Xiao, Y | 2 |
| Xia, H | 1 |
| Zhu, L | 1 |
| Chen, R | 1 |
| Yin, X | 1 |
| Feng, L | 1 |
| Yu, M | 1 |
| Lou, J | 1 |
| Seo, J | 2 |
| Lee, C | 2 |
| Hwang, HS | 2 |
| Kim, B | 1 |
| Thao, le Q | 1 |
| Lee, ES | 2 |
| Oh, KT | 1 |
| Lim, JL | 1 |
| Choi, HG | 2 |
| Youn, YS | 2 |
| Jin, M | 2 |
| Wu, Y | 2 |
| Zang, B | 1 |
| Tan, L | 1 |
| Chen, ZJ | 1 |
| Fang, YS | 1 |
| Zhang, AX | 1 |
| Yang, ZF | 1 |
| Yuan, ZY | 1 |
| Ning, W | 1 |
| McKay-Corkum, G | 1 |
| Chung, S | 1 |
| White, A | 1 |
| Scroggins, BT | 1 |
| Mitchell, JB | 1 |
| Mulligan-Kehoe, MJ | 1 |
| Citrin, D | 1 |
| Thao, LQ | 1 |
| Lee, S | 1 |
| Lee, EH | 1 |
| Turgut, NH | 2 |
| Kara, H | 2 |
| Elagoz, S | 1 |
| Deveci, K | 1 |
| Gungor, H | 1 |
| Arslanbas, E | 1 |
| Lucattelli, M | 1 |
| Fineschi, S | 2 |
| Selvi, E | 1 |
| Garcia Gonzalez, E | 1 |
| Bartalesi, B | 1 |
| De Cunto, G | 1 |
| Lorenzini, S | 1 |
| Galeazzi, M | 1 |
| Lungarella, G | 1 |
| Abuelezz, SA | 1 |
| Hendawy, N | 1 |
| Osman, WM | 1 |
| Javad-Mousavi, SA | 1 |
| Mehrzadi, S | 1 |
| Hosseinzadeh, A | 1 |
| Houshmand, G | 1 |
| Rashidi Nooshabadi, MR | 1 |
| Mehrabani, M | 1 |
| Goudarzi, M | 1 |
| He, L | 1 |
| Hu, C | 1 |
| Zhan, H | 1 |
| Huang, F | 1 |
| Ma, W | 1 |
| Zhao, Z | 1 |
| Kabel, AM | 1 |
| Omar, MS | 1 |
| Elmaaboud, MAA | 1 |
| Liang, J | 1 |
| Xie, T | 1 |
| Liu, N | 2 |
| Geng, Y | 1 |
| Kurkciyan, A | 1 |
| Mena, JM | 1 |
| Stripp, BR | 1 |
| Jiang, D | 1 |
| Noble, PW | 1 |
| Lucarini, L | 1 |
| Durante, M | 1 |
| Lanzi, C | 1 |
| Pini, A | 1 |
| Boccalini, G | 1 |
| Calosi, L | 1 |
| Moroni, F | 1 |
| Masini, E | 1 |
| Mannaioni, G | 1 |
| Zargar, HR | 1 |
| Javad-Moosavi, SA | 1 |
| An, G | 1 |
| Liang, D | 1 |
| Lian, X | 1 |
| Guo, C | 1 |
| Yang, T | 1 |
| Jia, Y | 1 |
| Ma, Y | 2 |
| Cao, L | 1 |
| Qiao, B | 1 |
| Feng, SY | 1 |
| Cleveland, ZI | 1 |
| Zhou, YM | 1 |
| Akinyi, TG | 1 |
| Dunn, RS | 1 |
| Davidson, CR | 1 |
| Guo, J | 2 |
| Woods, JC | 1 |
| Yamada, Y | 1 |
| Takanashi, M | 1 |
| Sudo, K | 1 |
| Ueda, S | 1 |
| Ohno, SI | 1 |
| Kuroda, M | 2 |
| Helal, GK | 1 |
| Helal, OK | 1 |
| Nazari, Z | 2 |
| Samei, M | 1 |
| Lv, L | 1 |
| Tao, S | 1 |
| Teng, L | 1 |
| Cao, J | 1 |
| Fujita, M | 3 |
| Mizuta, Y | 1 |
| Ikegame, S | 2 |
| Ouchi, H | 2 |
| Harada, E | 2 |
| Inoshima, I | 4 |
| Yoshimi, M | 3 |
| Watanabe, K | 1 |
| Nakanishi, Y | 3 |
| Sun, R | 1 |
| Mo, Z | 1 |
| Yang, Z | 1 |
| Liao, D | 1 |
| Zhong, N | 1 |
| Furonaka, M | 1 |
| Hattori, N | 1 |
| Tanimoto, T | 1 |
| Senoo, T | 1 |
| Ishikawa, N | 1 |
| Fujitaka, K | 1 |
| Haruta, Y | 1 |
| Yokoyama, A | 1 |
| Kohno, N | 1 |
| Zhao, CJ | 1 |
| Niu, JZ | 3 |
| Wang, JF | 3 |
| Zhou, G | 2 |
| Tang, BH | 1 |
| Ou, XM | 1 |
| Li, WC | 1 |
| Liu, DS | 2 |
| Li, YP | 1 |
| Wen, FQ | 2 |
| Feng, YL | 1 |
| Zhang, SF | 2 |
| Huang, XY | 1 |
| Wang, T | 2 |
| Wang, K | 1 |
| Hu, B | 1 |
| Choi, YY | 1 |
| Chung, M | 1 |
| Lowe, JB | 1 |
| Gonzalez, ET | 1 |
| Iyer, SS | 1 |
| Mac, V | 1 |
| Mora, AL | 2 |
| Sutliff, RL | 1 |
| Reed, A | 1 |
| Brigham, KL | 1 |
| Kelly, P | 1 |
| Rojas, M | 2 |
| Inage, M | 1 |
| Nakamura, H | 1 |
| Saito, H | 1 |
| Abe, S | 3 |
| Hino, T | 1 |
| Takabatake, N | 1 |
| Terashita, K | 1 |
| Ogura, M | 1 |
| Kato, S | 1 |
| Hosokawa, T | 1 |
| Sata, M | 1 |
| Tomoike, H | 1 |
| Huang, W | 1 |
| Cui, Y | 2 |
| Zhang, S | 2 |
| Zhou, J | 1 |
| Wei, Z | 1 |
| Yao, Z | 1 |
| Sun, BB | 1 |
| Li, JQ | 1 |
| Liu, L | 1 |
| Xu, D | 1 |
| Chen, YJ | 1 |
| Tsujimura, T | 1 |
| Ono-Kishino, M | 1 |
| Nagamine, J | 1 |
| Sugaru, E | 1 |
| Tokunaga, T | 1 |
| Kitoh, M | 1 |
| Nagata, R | 1 |
| Nakagawa, T | 1 |
| Taiji, M | 1 |
| Robb, WB | 1 |
| Condron, C | 1 |
| Moriarty, M | 1 |
| Walsh, TN | 1 |
| Bouchier-Hayes, DJ | 1 |
| Huang, MM | 1 |
| He, CC | 1 |
| Li, JX | 3 |
| Fujibayashi, T | 1 |
| Hashimoto, N | 1 |
| Jijiwa, M | 1 |
| Hasegawa, Y | 1 |
| Kojima, T | 1 |
| Ishiguro, N | 1 |
| Remund, K | 1 |
| Rechsteiner, T | 1 |
| Guo, Z | 2 |
| Hofer, M | 1 |
| Boehler, A | 1 |
| Qiao, J | 1 |
| Bi, J | 1 |
| Deng, G | 1 |
| He, G | 1 |
| Luan, Z | 1 |
| Lv, N | 1 |
| Xu, T | 1 |
| Chang, Q | 1 |
| Huang, Y | 1 |
| Guo, Q | 1 |
| Kang, CM | 1 |
| Moon, HS | 1 |
| Park, SH | 1 |
| Zhu, Y | 1 |
| Xiang, R | 1 |
| Huang, K | 1 |
| Ramsgaard, L | 1 |
| Englert, JM | 2 |
| Tobolewski, J | 1 |
| Tomai, L | 1 |
| Fattman, CL | 5 |
| Leme, AS | 1 |
| Kaynar, AM | 1 |
| Shapiro, SD | 1 |
| Enghild, JJ | 2 |
| Oury, TD | 6 |
| Namba, T | 1 |
| Tanaka, KI | 1 |
| Ito, Y | 1 |
| Hoshino, T | 1 |
| Matoyama, M | 1 |
| Yamakawa, N | 1 |
| Isohama, Y | 1 |
| Tripathi, SS | 1 |
| Mishra, V | 1 |
| Shukla, M | 1 |
| Verma, M | 1 |
| Chaudhury, BP | 1 |
| Kumar, P | 1 |
| Chhabra, JK | 1 |
| Pandey, HP | 1 |
| Paul, B | 1 |
| Matsui, K | 1 |
| Ueda, H | 2 |
| Terada, M | 2 |
| Azuma, N | 1 |
| Okamura, H | 2 |
| Sano, H | 1 |
| Shimbori, C | 3 |
| Shiota, N | 3 |
| Okunishi, H | 3 |
| Baowen, Q | 1 |
| Yulin, Z | 1 |
| Xin, W | 1 |
| Wenjing, X | 1 |
| Hao, Z | 1 |
| Zhizhi, C | 1 |
| Xingmei, D | 1 |
| Yuquan, W | 1 |
| Lijuan, C | 1 |
| Nagai, T | 1 |
| Tanaka, M | 1 |
| Hasui, K | 1 |
| Shirahama, H | 1 |
| Kitajima, S | 1 |
| Yonezawa, S | 1 |
| Xu, B | 1 |
| Matsuyama, T | 1 |
| Kim, JW | 1 |
| Kim, YH | 1 |
| Kim, SC | 1 |
| Kim, KH | 1 |
| Adachi, K | 1 |
| Mizoguchi, K | 1 |
| Kawarada, S | 1 |
| Miyoshi, A | 1 |
| Suzuki, M | 2 |
| Chiba, S | 1 |
| Deki, T | 1 |
| Brass, DM | 2 |
| McGee, SP | 1 |
| Dunkel, MK | 2 |
| Reilly, SM | 2 |
| Tobolewski, JM | 1 |
| Sabo-Attwood, T | 1 |
| Ohbayashi, M | 1 |
| Yashiro, Y | 1 |
| Fukuwaka, S | 1 |
| Yasuda, M | 1 |
| Kohyama, N | 1 |
| Kobayashi, Y | 1 |
| Yamamoto, T | 2 |
| Zhi, Q | 1 |
| Qian, X | 1 |
| Jin, C | 1 |
| Zhou, D | 1 |
| Lv, F | 1 |
| Feng, LF | 1 |
| Jia, ZY | 1 |
| Zhu, LJ | 1 |
| Ju, L | 1 |
| Chen, JQ | 1 |
| Jiang, ZQ | 1 |
| Chen, RP | 1 |
| Ma, Z | 1 |
| Takato, H | 2 |
| Yasui, M | 2 |
| Ichikawa, Y | 2 |
| Waseda, Y | 2 |
| Inuzuka, K | 2 |
| Nishizawa, Y | 3 |
| Tagami, A | 2 |
| Fujimura, M | 2 |
| Nakao, S | 2 |
| Jia, H | 1 |
| Chen, XL | 2 |
| Chen, C | 1 |
| Hu, YY | 2 |
| Yun, XJ | 1 |
| Gou, L | 1 |
| Liu, Z | 1 |
| Wu, L | 1 |
| Shaker, OG | 1 |
| Sourour, DA | 1 |
| Lunardi, F | 1 |
| Villano, G | 1 |
| Perissinotto, E | 1 |
| Agostini, C | 1 |
| Rea, F | 1 |
| Gnoato, M | 1 |
| Bradaschia, A | 1 |
| Valente, M | 1 |
| Pontisso, P | 1 |
| Calabrese, F | 1 |
| Qi, B | 1 |
| Zheng, H | 1 |
| Chen, Z | 1 |
| Wei, X | 1 |
| Ma, L | 1 |
| Wei, Y | 1 |
| Luo, Y | 1 |
| Zang, BX | 1 |
| Kliment, CR | 1 |
| Crum, LP | 1 |
| Courey, AJ | 1 |
| Koh, TJ | 1 |
| Novak, ML | 1 |
| Warnock, M | 1 |
| Xue, B | 1 |
| Cunningham, AK | 1 |
| Lin, Y | 1 |
| Goldklang, MP | 1 |
| Simon, RH | 2 |
| Lawrence, DA | 1 |
| Milton, PL | 1 |
| Dickinson, H | 1 |
| Jenkin, G | 1 |
| Lim, R | 1 |
| Damazo, AS | 1 |
| Sampaio, AL | 1 |
| Nakata, CM | 1 |
| Flower, RJ | 1 |
| Perretti, M | 1 |
| Oliani, SM | 1 |
| Dong, Z | 1 |
| Tai, W | 1 |
| Chai, Y | 1 |
| Zhong, H | 1 |
| Zou, H | 1 |
| Pinart, M | 2 |
| Faffe, DS | 1 |
| Romero, PV | 2 |
| Agackiran, Y | 1 |
| Gul, H | 1 |
| Gunay, E | 1 |
| Akyurek, N | 1 |
| Memis, L | 1 |
| Gunay, S | 1 |
| Sirin, YS | 1 |
| Ide, T | 1 |
| McGrath, EE | 1 |
| Lawrie, A | 1 |
| Marriott, HM | 1 |
| Mercer, P | 1 |
| Cross, SS | 1 |
| Arnold, N | 1 |
| Singleton, V | 1 |
| Thompson, AA | 1 |
| Walmsley, SR | 1 |
| Renshaw, SA | 1 |
| Sabroe, I | 1 |
| Chambers, RC | 2 |
| Dockrell, DH | 1 |
| Whyte, MK | 1 |
| Ma, JY | 2 |
| Mercer, RR | 1 |
| Barger, M | 1 |
| Schwegler-Berry, D | 1 |
| Scabilloni, J | 1 |
| Ma, JK | 2 |
| Castranova, V | 2 |
| Zhang, YP | 1 |
| Li, WB | 2 |
| Wang, WL | 1 |
| Song, SX | 1 |
| Bai, LL | 1 |
| Yuan, YD | 1 |
| Akgedik, R | 1 |
| Akgedik, S | 1 |
| Karamanlı, H | 1 |
| Uysal, S | 1 |
| Bozkurt, B | 1 |
| Ozol, D | 1 |
| Armutcu, F | 3 |
| Yıldırım, Z | 5 |
| Spencer, JC | 1 |
| Potts-Kant, E | 1 |
| Latoche, JD | 1 |
| Auten, RL | 1 |
| Hollingsworth, JW | 1 |
| Mi, S | 1 |
| Hu, ZW | 1 |
| Hua, F | 1 |
| Tug, T | 1 |
| Karaoglu, A | 1 |
| Karatas, F | 1 |
| Ayan, E | 1 |
| Boran, C | 1 |
| Tug, E | 1 |
| El-Khouly, D | 1 |
| El-Bakly, WM | 1 |
| Awad, AS | 1 |
| El-Mesallamy, HO | 1 |
| El-Demerdash, E | 1 |
| Faxuan, W | 1 |
| Qin, Z | 1 |
| Dinglun, Z | 1 |
| Xiaohui, R | 1 |
| Liqiang, Z | 1 |
| Yajia, L | 1 |
| Wen, GY | 1 |
| Zhao, Y | 1 |
| Liu, YM | 1 |
| Simler, NR | 1 |
| Howell, DC | 1 |
| Marshall, RP | 1 |
| Goldsack, NR | 1 |
| Hasleton, PS | 2 |
| Laurent, GJ | 2 |
| Egan, JJ | 2 |
| Tzurel, A | 1 |
| Segel, MJ | 4 |
| Or, R | 3 |
| Goldstein, RH | 3 |
| Breuer, R | 5 |
| Kolb, M | 3 |
| Bonniaud, P | 1 |
| Galt, T | 2 |
| Sime, PJ | 5 |
| Kelly, MM | 1 |
| Margetts, PJ | 3 |
| Gauldie, J | 5 |
| London, L | 1 |
| Majeski, EI | 1 |
| Altman-Hamamdzic, S | 1 |
| Enockson, C | 1 |
| Paintlia, MK | 1 |
| Harley, RA | 1 |
| London, SD | 1 |
| Wang, Q | 7 |
| Hyde, DM | 16 |
| Gotwals, PJ | 3 |
| Giri, SN | 26 |
| Motlagh, ME | 1 |
| Goldasteh, S | 1 |
| Biring, I | 1 |
| Nguyen, T | 1 |
| Izbicki, G | 2 |
| Christensen, TG | 3 |
| Fine, A | 1 |
| Conner, MW | 3 |
| Cui, S | 1 |
| Lok, SS | 1 |
| Haider, Y | 1 |
| Howell, D | 1 |
| Stewart, JP | 1 |
| Churg, A | 3 |
| Wright, JL | 2 |
| Card, JW | 3 |
| Racz, WJ | 4 |
| Brien, JF | 7 |
| Massey, TE | 7 |
| Brewer, GJ | 1 |
| Ullenbruch, MR | 1 |
| Dick, R | 1 |
| Olivarez, L | 1 |
| Tsai, SF | 1 |
| Liu, BL | 1 |
| Liao, JW | 1 |
| Wang, JS | 1 |
| Hwang, JS | 1 |
| Wang, SC | 1 |
| Tzeng, YM | 1 |
| Ho, SP | 1 |
| Serrano-Mollar, A | 2 |
| Closa, D | 1 |
| Prats, N | 1 |
| Blesa, S | 1 |
| Martinez-Losa, M | 1 |
| Cortijo, J | 1 |
| Estrela, JM | 1 |
| Morcillo, EJ | 1 |
| Bulbena, O | 1 |
| Corbel, M | 2 |
| Caulet-Maugendre, S | 2 |
| Germain, N | 2 |
| Lagente, V | 3 |
| Boichot, E | 3 |
| Ortiz, LA | 1 |
| Gambelli, F | 1 |
| McBride, C | 1 |
| Gaupp, D | 1 |
| Baddoo, M | 1 |
| Kaminski, N | 3 |
| Phinney, DG | 1 |
| Margolin, SB | 3 |
| Cisneros-Lira, J | 1 |
| Gaxiola, M | 2 |
| Ramos, C | 1 |
| Selman, M | 4 |
| Pardo, A | 4 |
| Ruiz, V | 1 |
| Ordóñez, RM | 1 |
| Berumen, J | 1 |
| Ramírez, R | 2 |
| Uhal, B | 1 |
| Becerril, C | 1 |
| Tomimori, Y | 1 |
| Muto, T | 1 |
| Saito, K | 1 |
| Tanaka, T | 1 |
| Maruoka, H | 1 |
| Sumida, M | 1 |
| Fukami, H | 1 |
| Fukuda, Y | 2 |
| Chang, LY | 2 |
| Termin, TA | 1 |
| Petersen, L | 1 |
| Ozyurt, H | 2 |
| Söğüt, S | 2 |
| Kart, L | 2 |
| Iraz, M | 4 |
| Temel, I | 2 |
| Ozen, S | 2 |
| Uzun, A | 1 |
| Akyol, O | 2 |
| Otsuka, M | 1 |
| Takahashi, H | 1 |
| Shiratori, M | 1 |
| Chiba, H | 1 |
| Hernandez-Pando, R | 1 |
| Aguilar, D | 1 |
| Hernandez, ML | 1 |
| Orozco, H | 1 |
| Rook, G | 1 |
| Tanaka, H | 2 |
| Komai, M | 1 |
| Nagao, K | 1 |
| Ishizaki, M | 1 |
| Kajiwara, D | 1 |
| Takatsu, K | 1 |
| Delespesse, G | 1 |
| Nagai, H | 2 |
| Kuwano, K | 6 |
| Hamada, N | 1 |
| Maeyama, T | 4 |
| Hagimoto, N | 5 |
| Hara, N | 5 |
| Umeda, Y | 1 |
| Marui, T | 1 |
| Matsuno, Y | 1 |
| Shirahashi, K | 1 |
| Iwata, H | 1 |
| Takagi, H | 1 |
| Matsumoto, K | 1 |
| Nakamura, T | 1 |
| Kosugi, A | 1 |
| Mori, Y | 1 |
| Takemura, H | 1 |
| Cho, HY | 1 |
| Reddy, SP | 1 |
| Yamamoto, M | 1 |
| Kleeberger, SR | 2 |
| Peng, K | 1 |
| Chu, Q | 1 |
| Zhao, S | 1 |
| Kaplan, S | 1 |
| Murakami, S | 1 |
| Nagaya, N | 1 |
| Itoh, T | 1 |
| Fujii, T | 2 |
| Iwase, T | 1 |
| Hamada, K | 1 |
| Kimura, H | 1 |
| Kangawa, K | 1 |
| Kakugawa, T | 1 |
| Mukae, H | 1 |
| Hayashi, T | 2 |
| Ishii, H | 1 |
| Abe, K | 2 |
| Oku, H | 1 |
| Miyazaki, M | 1 |
| Kadota, J | 1 |
| Kohno, S | 1 |
| Okuma, T | 1 |
| Terasaki, Y | 1 |
| Kaikita, K | 1 |
| Kobayashi, H | 1 |
| Kuziel, WA | 1 |
| Kawasuji, M | 1 |
| Takeya, M | 1 |
| Ji, WJ | 1 |
| Gong, LK | 1 |
| Li, XH | 1 |
| Chen, FP | 1 |
| Qi, XM | 1 |
| Liu, LL | 1 |
| Liu, YZ | 1 |
| Wu, XF | 1 |
| Huang, CG | 2 |
| Ren, J | 1 |
| Zhou, Z | 3 |
| Song, R | 1 |
| Greenhill, S | 1 |
| Alber, S | 1 |
| Choi, AM | 2 |
| Morse, D | 1 |
| Zhang, DW | 1 |
| Yang, MJ | 1 |
| Wang, LQ | 1 |
| Liu, LQ | 1 |
| Gao, BH | 1 |
| El-Medany, A | 1 |
| Hagar, HH | 1 |
| Moursi, M | 1 |
| At Muhammed, R | 1 |
| El-Rakhawy, FI | 1 |
| El-Medany, G | 1 |
| Nakatani-Okuda, A | 1 |
| Kashiwamura, S | 1 |
| Sekiyama, A | 1 |
| Kubota, A | 1 |
| Fujita, Y | 1 |
| Adachi, S | 1 |
| Tsuji, Y | 1 |
| Tanizawa, T | 1 |
| Jin, Y | 1 |
| Lu, HP | 1 |
| Lai, GX | 1 |
| Matsuda, K | 2 |
| Aoyama, S | 1 |
| Shirokine, J | 1 |
| Kudo, S | 1 |
| Sunazuka, T | 2 |
| Omura, T | 1 |
| Chen, CM | 1 |
| Chou, HC | 1 |
| Hsu, HH | 1 |
| Wang, LF | 1 |
| Aqeilan, R | 1 |
| Zilka, K | 1 |
| Lorberboum-Galski, H | 1 |
| Wallach-Dayan, SB | 1 |
| Walters, DM | 1 |
| Antao-Menezes, A | 1 |
| Ingram, JL | 1 |
| Rice, AB | 1 |
| Nyska, A | 1 |
| Tani, Y | 1 |
| Bonner, JC | 1 |
| Kim, S | 1 |
| Chung, JH | 1 |
| Park, WS | 1 |
| Chung, DH | 1 |
| Lawson, WE | 1 |
| Polosukhin, VV | 1 |
| Stathopoulos, GT | 1 |
| Zoia, O | 1 |
| Han, W | 1 |
| Lane, KB | 1 |
| Li, B | 1 |
| Donnelly, EF | 1 |
| Holburn, GE | 1 |
| Lewis, KG | 1 |
| Collins, RD | 1 |
| Hull, WM | 1 |
| Glasser, SW | 1 |
| Whitsett, JA | 1 |
| Blackwell, TS | 1 |
| Kotuk, M | 2 |
| Erdogan, H | 2 |
| Yagmurca, M | 2 |
| Kuku, I | 1 |
| Fadillioglu, E | 2 |
| Ishida, Y | 1 |
| Takayasu, T | 1 |
| Kimura, A | 1 |
| Kakimoto, N | 1 |
| Miyashita, T | 1 |
| Kondo, T | 1 |
| Yao, HW | 1 |
| Zhu, JP | 1 |
| Zhao, MH | 1 |
| Usuki, J | 1 |
| Shimizu, T | 2 |
| Hirata, Y | 1 |
| Inagaki, H | 1 |
| Kawada, T | 1 |
| Takahashi, S | 1 |
| Kudoh, S | 1 |
| Omura, S | 1 |
| Shen, Y | 1 |
| Zhao, HL | 1 |
| Du, J | 1 |
| Li, YT | 1 |
| Tan, F | 1 |
| Pei, G | 1 |
| Kilic, T | 1 |
| Ermis, H | 1 |
| Fujimoto, H | 1 |
| Gabazza, EC | 2 |
| Taguchi, O | 2 |
| Nishii, Y | 1 |
| Nakahara, H | 1 |
| Bruno, NE | 1 |
| D'Alessandro-Gabazza, CN | 1 |
| Kasper, M | 1 |
| Yano, Y | 1 |
| Nagashima, M | 1 |
| Morser, J | 1 |
| Broze, GJ | 1 |
| Suzuki, K | 3 |
| Adachi, Y | 2 |
| Mizuguchi, S | 1 |
| Takemura, S | 1 |
| Minamiyama, Y | 1 |
| Kodai, S | 1 |
| Tsukioka, T | 1 |
| Inoue, K | 1 |
| Okada, S | 1 |
| Suehiro, S | 1 |
| Shang, Y | 1 |
| Ouyang, ZG | 1 |
| Zhen, YS | 1 |
| Lu, YS | 1 |
| Chen, WT | 1 |
| Li, ZH | 1 |
| Lin, TX | 1 |
| Ammar, YA | 1 |
| Ismail, MM | 1 |
| El-Sehrawi, HM | 1 |
| Noaman, E | 1 |
| Bayomi, AH | 1 |
| Shawer, TZ | 1 |
| Hu, P | 1 |
| Gao, ZC | 1 |
| Lakatos, HF | 1 |
| Burgess, HA | 1 |
| Thatcher, TH | 1 |
| Redonnet, MR | 1 |
| Hernady, E | 1 |
| Williams, JP | 1 |
| Zhang, HQ | 1 |
| Yau, YF | 1 |
| Szeto, KY | 1 |
| Chan, WT | 1 |
| Wong, J | 1 |
| Tian, XL | 1 |
| Yao, W | 1 |
| Guo, ZJ | 1 |
| Gu, L | 1 |
| Zhu, YJ | 1 |
| Molina, V | 1 |
| Haj-Yahia, S | 1 |
| Solodeev, I | 1 |
| Levy, Y | 1 |
| Blank, M | 1 |
| Shoenfeld, Y | 1 |
| Wang, XM | 1 |
| Kim, HP | 1 |
| Feghali-Bostwick, CA | 1 |
| Ifedigbo, E | 1 |
| Xu, X | 1 |
| Zhang, GC | 1 |
| Hou, J | 1 |
| Torres-González, E | 1 |
| Ritzenthaler, J | 1 |
| Speck, SH | 1 |
| Roman, J | 1 |
| Brigham, K | 1 |
| Stecenko, A | 1 |
| Pierce, EM | 1 |
| Carpenter, K | 1 |
| Jakubzick, C | 1 |
| Kunkel, SL | 2 |
| Flaherty, KR | 1 |
| Martinez, FJ | 1 |
| Hogaboam, CM | 1 |
| Izumo, T | 1 |
| Kondo, M | 1 |
| Nagai, A | 2 |
| Li, YQ | 1 |
| Tajima, S | 2 |
| Bando, M | 2 |
| Ohno, S | 2 |
| Sugiyama, Y | 2 |
| Oshikawa, K | 1 |
| Tominaga, S | 1 |
| Itoh, K | 1 |
| Takada, T | 2 |
| Suzuki, E | 2 |
| Gejyo, F | 2 |
| Arafa, HM | 1 |
| Abdel-Wahab, MH | 1 |
| El-Shafeey, MF | 1 |
| Badary, OA | 1 |
| Hamada, FM | 1 |
| Ahmed, KM | 1 |
| Nantajit, D | 1 |
| Rosenthal, FS | 1 |
| Hai, CX | 1 |
| Li, JJ | 2 |
| Manoury, B | 1 |
| Nénan, S | 1 |
| Guénon, I | 1 |
| Wang, SJ | 2 |
| Bai, W | 2 |
| Wang, CL | 2 |
| Hagiwara, S | 1 |
| Iwasaka, H | 1 |
| Matsumoto, S | 1 |
| Noguchi, T | 1 |
| Pochetuhen, K | 1 |
| Luzina, IG | 1 |
| Lockatell, V | 1 |
| Choi, J | 1 |
| Todd, NW | 1 |
| Atamas, SP | 1 |
| Ng, LT | 1 |
| Yen, FL | 1 |
| Liao, CW | 1 |
| Lin, CC | 1 |
| Tan, SZ | 1 |
| Liu, CH | 1 |
| Lu, X | 1 |
| Ye, WC | 1 |
| Cai, ZZ | 1 |
| Liu, P | 1 |
| Cabrera, S | 1 |
| Arreola, JL | 1 |
| Jara, P | 1 |
| D'Armiento, J | 1 |
| Richards, T | 1 |
| Langenbach, SY | 1 |
| Wheaton, BJ | 1 |
| Fernandes, DJ | 1 |
| Jones, C | 1 |
| Sutherland, TE | 1 |
| Wraith, BC | 1 |
| Harris, T | 1 |
| Schuliga, MJ | 1 |
| McLean, C | 1 |
| Stewart, AG | 1 |
| Long, X | 1 |
| Xiong, SD | 1 |
| Xiong, WN | 1 |
| Xu, YJ | 1 |
| Negri, EM | 1 |
| Cabrera, R | 1 |
| Rocco, PR | 1 |
| Yamasawa, H | 1 |
| Moriyama, H | 1 |
| Zheng, MH | 1 |
| Dai, MS | 1 |
| Lin, LF | 1 |
| Conventz, A | 1 |
| Musiol, A | 1 |
| Brodowsky, C | 1 |
| Müller-Lux, A | 1 |
| Dewes, P | 1 |
| Kraus, T | 1 |
| Schettgen, T | 1 |
| Chen, N | 1 |
| Xue, XD | 1 |
| Satomi, Y | 1 |
| Sakaguchi, K | 1 |
| Kasahara, Y | 1 |
| Akahori, F | 2 |
| Dai, Z | 1 |
| Ask, K | 1 |
| Labiris, R | 1 |
| Farkas, L | 1 |
| Moeller, A | 1 |
| Froese, A | 1 |
| Farncombe, T | 1 |
| McClelland, GB | 1 |
| Inman, M | 1 |
| Kolb, MR | 1 |
| Bongiovanni, M | 1 |
| Donati, Y | 1 |
| Djaafar, S | 1 |
| Naso, F | 1 |
| Goffin, L | 1 |
| Argiroffo, CB | 1 |
| Pache, JC | 1 |
| Dayer, JM | 1 |
| Ferrari-Lacraz, S | 1 |
| Chizzolini, C | 1 |
| Troitskaia, NA | 1 |
| Velichkovskiĭ, BT | 1 |
| Kogan, FM | 1 |
| El'nichnykh, LN | 1 |
| Thrall, RS | 2 |
| Ward, PA | 1 |
| Clark, JG | 2 |
| Overton, JE | 1 |
| Marino, BA | 1 |
| Uitto, J | 3 |
| Starcher, BC | 1 |
| Riley, DJ | 5 |
| Kerr, JS | 2 |
| Berg, RA | 2 |
| Ianni, BD | 1 |
| Pietra, GG | 1 |
| Edelman, NH | 2 |
| Prockop, DJ | 2 |
| Counts, DF | 1 |
| Evans, JN | 1 |
| Dipetrillo, TA | 1 |
| Sterling, KM | 1 |
| Kelley, J | 1 |
| Hakkinen, PJ | 2 |
| Whiteley, JW | 1 |
| Witschi, HR | 1 |
| Schrier, D | 1 |
| McGarry, B | 1 |
| Duque, RE | 1 |
| Schrier, DJ | 1 |
| McGarry, BM | 1 |
| Lazo, JS | 2 |
| Humphreys, CJ | 1 |
| McAnulty, RJ | 1 |
| Yoshida, A | 1 |
| Yamada, T | 1 |
| Hiramatsu, M | 1 |
| Kiuchi, H | 1 |
| Sekiya, S | 1 |
| Kawaguchi, T | 1 |
| Yamamoto, K | 2 |
| Yu, SY | 2 |
| Newman, RA | 1 |
| Hacker, MP | 1 |
| Sakai, TT | 1 |
| Misra, HP | 1 |
| Chandler, DB | 4 |
| Chen, ZL | 1 |
| Woźniak, H | 2 |
| Kehrer, JP | 8 |
| Klein-Szanto, AJ | 2 |
| Sorensen, EM | 1 |
| Pearlman, R | 1 |
| Rosner, MH | 1 |
| Schmoyer, RL | 1 |
| Witschi, HP | 4 |
| Ward, WF | 4 |
| Shih-Hoellwarth, A | 1 |
| Tuttle, RD | 1 |
| Guzeeva, SA | 1 |
| Tikhonov, VA | 1 |
| Adamson, IY | 7 |
| Bowden, DH | 7 |
| Haschek, WM | 5 |
| Last, JA | 6 |
| Reiser, KM | 2 |
| Witschi, H | 8 |
| Magdon, E | 1 |
| Klaus, H | 1 |
| Meyer, KR | 2 |
| Ullrich, RL | 2 |
| Dalbey, WE | 1 |
| Gościcki, J | 1 |
| Bielichowska, G | 1 |
| Szendzikowski, S | 1 |
| Lao, I | 1 |
| Nagareda, T | 1 |
| Tanaka, A | 1 |
| Terada, N | 1 |
| Imakon, Y | 1 |
| Shiomi, H | 1 |
| Matsubara, H | 1 |
| Noro, A | 1 |
| Hollinger, MA | 2 |
| Hua, G | 1 |
| Chu, Y | 1 |
| Chen, W | 1 |
| McLaughlin, GE | 1 |
| Frank, L | 1 |
| Bakowska, J | 1 |
| Piguet, PF | 3 |
| Vesin, C | 2 |
| Poiani, GJ | 2 |
| Greco, M | 1 |
| Choe, JK | 2 |
| Fox, JD | 2 |
| Smith, RE | 1 |
| Strieter, RM | 2 |
| Lukacs, NW | 1 |
| Huffnagle, GB | 1 |
| Wilke, CA | 1 |
| Burdick, MD | 2 |
| Lincoln, P | 1 |
| Evanoff, H | 1 |
| Wild, JS | 2 |
| Blaisdell, R | 1 |
| Rucker, RB | 1 |
| Wang, CM | 1 |
| He, QZ | 1 |
| Zhang, RX | 1 |
| Iyer, SN | 2 |
| Schiedt, MJ | 1 |
| Mori, H | 2 |
| Kawada, K | 2 |
| Koda, A | 2 |
| Driscoll, KE | 2 |
| Maurer, JK | 2 |
| Higgins, J | 2 |
| Poynter, J | 2 |
| Denis, M | 2 |
| Bisson, D | 1 |
| Quinlan, TR | 2 |
| BéruBé, KA | 1 |
| Marsh, JP | 3 |
| Janssen, YM | 2 |
| Taishi, P | 1 |
| Leslie, KO | 2 |
| Hemenway, D | 3 |
| O'Shaughnessy, PT | 1 |
| Vacek, P | 2 |
| Mossman, BT | 3 |
| Hirose, N | 1 |
| Lynch, DA | 1 |
| Cherniack, RM | 3 |
| Doherty, DE | 1 |
| Grau, GE | 1 |
| Thompson, RC | 1 |
| Blake, TL | 2 |
| Reasor, MJ | 4 |
| Stein-Streilein, J | 5 |
| Corsini, E | 1 |
| Luster, MI | 1 |
| Mahler, J | 1 |
| Craig, WA | 1 |
| Blazka, ME | 1 |
| Rosenthal, GJ | 1 |
| Gelzleichter, TR | 2 |
| Harkema, J | 1 |
| Hawk, S | 1 |
| Rafeiro, E | 1 |
| Leeder, RG | 3 |
| Kabalka, GW | 1 |
| Chatla, N | 1 |
| Forkert, PG | 1 |
| Forkert, L | 1 |
| Evans, CD | 1 |
| Pinkerton, KE | 2 |
| Walker, RM | 1 |
| Nagata, T | 1 |
| Masaoka, T | 1 |
| Okinaka, T | 1 |
| Ohtsuka, Y | 1 |
| Munakata, M | 1 |
| Ukita, H | 1 |
| Takahashi, T | 2 |
| Satoh, A | 1 |
| Homma, Y | 1 |
| Kawakami, Y | 1 |
| Eitzman, DT | 2 |
| McCoy, RD | 1 |
| Zheng, X | 1 |
| Fay, WP | 1 |
| Shen, T | 1 |
| Ginsburg, D | 1 |
| Blaisdell, RJ | 1 |
| Reinhart, PG | 1 |
| Lai, YL | 1 |
| Gairola, CG | 1 |
| Zhu, J | 3 |
| Kaplan, AM | 4 |
| Goud, SN | 2 |
| Braun, RK | 2 |
| Sterner-Kock, A | 1 |
| Kilshaw, PJ | 1 |
| Ferrick, DA | 1 |
| Pääkkö, P | 2 |
| Anttila, S | 1 |
| Sormunen, R | 1 |
| Ala-Kokko, L | 2 |
| Peura, R | 1 |
| Ferrans, VJ | 1 |
| Ryhänen, L | 2 |
| Cohen, DA | 3 |
| Van, GY | 1 |
| Weinbach, J | 1 |
| Camus, A | 1 |
| Barra, J | 1 |
| Dumont, P | 1 |
| Julian, M | 1 |
| Cros, S | 1 |
| Babinet, C | 1 |
| Tiraby, G | 1 |
| Suzuki, N | 1 |
| Ohta, K | 1 |
| Horiuchi, T | 2 |
| Takizawa, H | 1 |
| Ueda, T | 2 |
| Kuwabara, M | 1 |
| Shiga, J | 1 |
| Ito, K | 1 |
| DiMatteo, M | 1 |
| Suntres, ZE | 1 |
| Shek, PN | 1 |
| Greco, MJ | 1 |
| Kemnitzer, JE | 1 |
| Kohn, J | 1 |
| Pelouch, V | 1 |
| Kolár, F | 1 |
| Ost'ádal, B | 1 |
| Milerová, M | 1 |
| Cihák, R | 1 |
| Widimský, J | 1 |
| Ziboh, VA | 1 |
| Yun, M | 1 |
| Xing, Z | 2 |
| Graham, FL | 1 |
| Csaky, KG | 1 |
| Ts'ao, C | 1 |
| Tsao, FH | 1 |
| Taylor, JM | 1 |
| Molteni, A | 2 |
| Miyazaki, H | 2 |
| Kunitake, R | 4 |
| Kawasaki, M | 4 |
| Kaneko, Y | 1 |
| Ben Yehuda, A | 1 |
| Lossos, IS | 1 |
| Ben Chetrit, E | 1 |
| Schelegle, ES | 1 |
| Mansoor, JK | 1 |
| Giri, S | 1 |
| Gaarde, W | 1 |
| Harper, JR | 1 |
| Pierschbacher, MD | 1 |
| Zhao, W | 1 |
| Yu, R | 2 |
| Hou, XM | 1 |
| Huaux, F | 2 |
| Louahed, J | 1 |
| Hudspith, B | 1 |
| Meredith, C | 1 |
| Delos, M | 2 |
| Renauld, JC | 2 |
| Lison, D | 2 |
| Song, L | 2 |
| Cui, X | 2 |
| Shi, Z | 1 |
| Hu, W | 1 |
| Franco, L | 1 |
| Najvar, L | 1 |
| Gomez, BL | 1 |
| Restrepo, S | 1 |
| Graybill, JR | 1 |
| Restrepo, A | 1 |
| Venkatesan, N | 1 |
| Punithavathi, D | 1 |
| Chandrakasan, G | 1 |
| Okazaki, T | 2 |
| Hirota, S | 1 |
| Xu, ZD | 1 |
| Maeyama, K | 1 |
| Nakama, A | 1 |
| Kawano, S | 1 |
| Hori, M | 1 |
| Kitamura, Y | 1 |
| Dai, J | 1 |
| Gilks, B | 1 |
| Price, K | 1 |
| Gurujeyalakshmi, G | 3 |
| Helene, M | 1 |
| Lake-Bullock, V | 1 |
| Bray, TM | 1 |
| Yatomi, T | 1 |
| Nakamura, N | 1 |
| Nagata, S | 1 |
| Suda, T | 1 |
| Barger, MW | 1 |
| Hubbs, AF | 3 |
| Weber, SL | 1 |
| Koteliansky, VE | 1 |
| Ryan, ST | 2 |
| Strandjord, TP | 1 |
| Madtes, DK | 1 |
| Weiss, DJ | 1 |
| Sage, EH | 1 |
| Antonini, JM | 3 |
| Charron, TG | 1 |
| Roberts, JR | 2 |
| Lai, J | 1 |
| Rogers, RA | 1 |
| Yoshida, M | 1 |
| Sakuma-Mochizuki, J | 1 |
| Arai, T | 2 |
| Mori, M | 3 |
| Goya, S | 2 |
| Matsuoka, H | 2 |
| Hayashi, S | 2 |
| Kaneda, Y | 1 |
| Kishimoto, T | 1 |
| Hemenway, DR | 2 |
| Davis, GS | 1 |
| Tamagawa, K | 1 |
| Taooka, Y | 1 |
| Maeda, A | 1 |
| Hiyama, K | 1 |
| Ishioka, S | 1 |
| Yamakido, M | 1 |
| Baumann, M | 2 |
| Appold, S | 1 |
| Geyer, P | 1 |
| Knorr, A | 2 |
| Voigtmann, L | 2 |
| Herrmann, T | 2 |
| Hagiwara, SI | 1 |
| Ishii, Y | 2 |
| Kitamura, S | 1 |
| Aoshiba, K | 1 |
| Yasui, S | 1 |
| Tamaoki, J | 1 |
| Betsuyaku, T | 1 |
| Parks, WC | 1 |
| Shipley, JM | 1 |
| Senior, RM | 1 |
| Christensen, PJ | 1 |
| Bailie, MB | 1 |
| Goodman, RE | 1 |
| O'Brien, AD | 1 |
| Toews, GB | 2 |
| Paine, R | 1 |
| Takagawa, S | 1 |
| Nishioka, K | 1 |
| Hirano, K | 1 |
| Morishima, Y | 1 |
| Masuyama, K | 1 |
| Goto, Y | 1 |
| Nomura, A | 1 |
| Sakamoto, T | 1 |
| Uchida, Y | 1 |
| Sagai, M | 1 |
| Sekizawa, K | 1 |
| Taylor, MD | 2 |
| Van Dyke, K | 1 |
| Bowman, LL | 1 |
| Miles, PR | 1 |
| Mason, RJ | 2 |
| Shannon, K | 1 |
| Savani, RC | 1 |
| Arguiri, E | 1 |
| Wang, S | 1 |
| Vu, D | 1 |
| Howe, CC | 1 |
| DeLisser, HM | 1 |
| Jennings, CD | 1 |
| Bryson, JS | 1 |
| Lobb, RR | 1 |
| Dohi, M | 1 |
| Hasegawa, T | 1 |
| Marshall, BC | 1 |
| Zhang-Hoover, J | 2 |
| Sutton, A | 2 |
| van Rooijen, N | 1 |
| Matsuba, T | 1 |
| Yoshida, K | 1 |
| Shimizu, Y | 1 |
| Dobashi, K | 1 |
| Iizuka, K | 1 |
| Horie, T | 1 |
| Tukagoshi, H | 1 |
| Nakazawa, T | 1 |
| Nakazato, Y | 1 |
| Takahashi, F | 1 |
| Takahashi, K | 1 |
| Maeda, K | 1 |
| Ienaga, H | 1 |
| Maeda, M | 1 |
| Kon, S | 1 |
| Uede, T | 1 |
| Fukuchi, Y | 1 |
| Schmidt, M | 1 |
| Molet, S | 1 |
| Pauluhn, J | 1 |
| Hirth-Dietrich, C | 1 |
| Rosenbruch, M | 1 |
| Arras, M | 1 |
| Vink, A | 1 |
| Coutelier, JP | 1 |
| Many, MC | 1 |
| Barbarin, V | 1 |
| Xu, Z | 1 |
| Westrick, RJ | 1 |
| Shen, YC | 1 |
| Yasui, H | 1 |
| Tamaki, S | 1 |
| Kobayashi, T | 1 |
| Hataji, O | 1 |
| Yuda, H | 1 |
| Shimizu, S | 1 |
| Keane, MP | 1 |
| Belperio, JA | 1 |
| Thakker, K | 1 |
| Menache, M | 1 |
| Crapo, JD | 1 |
| Day, BJ | 1 |
| Chung, WH | 1 |
| Bennett, BM | 1 |
| Huang, SS | 1 |
| Wang, DH | 1 |
| Wang, XL | 1 |
| Sakamoto, H | 1 |
| Zhao, LH | 1 |
| Jain, F | 1 |
| Kradin, R | 1 |
| Peters-Golden, M | 1 |
| Bailie, M | 1 |
| Marshall, T | 1 |
| Wilke, C | 1 |
| Lü, C | 1 |
| Hou, X | 1 |
| Candan, F | 1 |
| Alagözlü, H | 1 |
| Zuo, F | 1 |
| Eugui, E | 1 |
| Allard, J | 1 |
| Yakhini, Z | 1 |
| Ben-Dor, A | 1 |
| Lollini, L | 1 |
| Morris, D | 1 |
| Kim, Y | 1 |
| DeLustro, B | 1 |
| Sheppard, D | 1 |
| Heller, RA | 1 |
| Nagase, T | 1 |
| Uozumi, N | 1 |
| Ishii, S | 1 |
| Kita, Y | 1 |
| Yamamoto, H | 1 |
| Ohga, E | 1 |
| Ouchi, Y | 1 |
| Hallahan, DE | 1 |
| Geng, L | 1 |
| Shyr, Y | 1 |
| Kida, H | 1 |
| Morishita, H | 1 |
| Fujiwara, H | 1 |
| Tachibana, I | 1 |
| Osaki, T | 1 |
| Griffin, M | 1 |
| Smith, LL | 1 |
| Wynne, J | 1 |
| Heppleston, AG | 1 |
| Zapol, WM | 1 |
| Trelstad, RL | 1 |
| Coffey, JW | 1 |
| Tsai, I | 1 |
| Salvador, RA | 1 |
| Dubrawsky, C | 1 |
| Dubravsky, NB | 1 |
| Withers, HR | 1 |
| Greenberg, DB | 1 |
| Lyons, SA | 1 |
| Gross, NJ | 1 |
| Ueda, A | 1 |
| Nomura, S | 1 |
| Onizuka, R | 1 |
| Sumiyoshi, A | 1 |
| Hayashi, E | 1 |
| Kitano, S | 1 |
| Shibuta, H | 1 |
| Percarpio, B | 1 |
| Fischer, JJ | 1 |
| Pickrell, JA | 2 |
| Harris, DV | 1 |
| Pfleger, RC | 1 |
| Benjamin, SA | 1 |
| Belasich, JJ | 1 |
| Jones, RK | 1 |
| McClellan, RO | 1 |
| Ceglecka-Tomaszewska, K | 1 |
| Iwańska, J | 1 |
| Tryczyńska, M | 1 |
| Chvapil, M | 1 |
| Peng, YM | 1 |
| Zia, S | 1 |
| Wang, XZ | 1 |
| O'Neill, CA | 2 |
| Prieditis, H | 1 |
| Jakab, GJ | 3 |
| Szaflarska-Stojko, E | 3 |
| Olczyk, D | 1 |
| Domagała, B | 1 |
| Stojko, J | 1 |
| Ociepiński, M | 3 |
| Perricone, MA | 1 |
| Hernnäs, J | 1 |
| Nettelbladt, O | 1 |
| Bjermer, L | 1 |
| Särnstrand, B | 1 |
| Malmström, A | 1 |
| Hällgren, R | 1 |
| Ubaĭdullaev, AM | 1 |
| Liverko, IV | 1 |
| Chernik, MB | 1 |
| Kimura, R | 1 |
| Asquith, T | 1 |
| Miller, NS | 1 |
| Kanekal, S | 1 |
| Fraiser, L | 1 |
| Harris, JA | 1 |
| Wang, QJ | 2 |
| Stovall, MY | 1 |
| Zyłka-Włoszczyk, M | 2 |
| Kuroki, Y | 1 |
| Grant, MM | 1 |
| Burnett, CM | 1 |
| Fein, AM | 1 |
| Graver, DF | 1 |
| Zhang, P | 1 |
| Uesugi, Y | 1 |
| Sakamoto, O | 1 |
| Wiessner, JH | 2 |
| Mandel, NS | 2 |
| Sohnle, PG | 2 |
| Hasegawa, A | 1 |
| Mandel, GS | 2 |
| Sesko, A | 1 |
| Hill, S | 1 |
| Shatos, MA | 1 |
| Doherty, J | 1 |
| Petruska, J | 1 |
| Adler, KB | 1 |
| Mickey, R | 1 |
| Kaminskaia, GO | 1 |
| Puriaeva, NL | 1 |
| Stepanian, IE | 1 |
| Bassett, DJ | 1 |
| van Rongen, E | 1 |
| Madhuizen, HT | 1 |
| Tan, CH | 1 |
| Durham, SK | 1 |
| Gijbels, MJ | 1 |
| DiGiovanni, J | 1 |
| Matalon, S | 1 |
| Harper, WV | 1 |
| Goldinger, JM | 1 |
| Nickerson, PA | 1 |
| Olszowka, J | 1 |
| Sendelbach, LE | 1 |
| Lindenschmidt, RC | 5 |
| Bigby, TD | 1 |
| Allen, D | 1 |
| Leslie, CG | 1 |
| Henson, PM | 1 |
| Tryka, AF | 3 |
| Kennedy, JI | 3 |
| Fulmer, JD | 3 |
| Geismar, LS | 1 |
| Hennessey, S | 1 |
| Lee, YC | 2 |
| Smith, RD | 1 |
| Godfrey, GA | 1 |
| Frome, EL | 1 |
| Marafino, BJ | 1 |
| Quinones, F | 1 |
| Crouch, E | 1 |
| Chovan, JP | 1 |
| Diccianni, MB | 1 |
| Raisfeld-Danse, IH | 1 |
| Bacchi, CJ | 1 |
| Nathan, HC | 1 |
| Greenberg, J | 1 |
| Wert, MB | 2 |
| Grizzle, WE | 2 |
| Harrison, JH | 1 |
| Veninga, TS | 1 |
| Vriesendorp, R | 1 |
| Blom-Muilwijk, MC | 1 |
| Sleyfer, DT | 1 |
| Konings, AW | 1 |
| van Gool, J | 1 |
| De Nie, I | 1 |
| van Vugt, H | 1 |
| Brugman, AM | 1 |
| Coursin, DB | 1 |
| Cihla, HP | 1 |
| Baer, KE | 1 |
| Rutherford, JE | 1 |
| Letourneau, HL | 1 |
| Sharplin, J | 1 |
| Franko, AJ | 1 |
| Hinz, JM | 1 |
| Daniels, JM | 1 |
| Henderson, JD | 1 |
| Shiotsuka, RN | 1 |
| Yermakoff, JK | 1 |
| Osheroff, MR | 1 |
| Drew, RT | 1 |
| Ts'ao, CH | 1 |
| Solliday, NH | 1 |
| Dunne, M | 1 |
| Królikowska-Prasał, I | 1 |
| Staszyc, J | 1 |
| Matysiak, W | 1 |
| Kifer, E | 1 |
| Romanowska-Sarlej, J | 1 |
| Zaranko, W | 1 |
| Young, L | 1 |
| Wright, ES | 1 |
| White, DM | 1 |
| Smiler, KL | 1 |
| Lipscomb, MF | 1 |
| Fisch, H | 1 |
| Whitney, PL | 1 |
| Dubaybo, BA | 2 |
| Durr, RA | 1 |
| Thet, LA | 2 |
| Yamaguchi, M | 1 |
| Togashi, H | 1 |
| Arai, H | 1 |
| Motomiya, M | 1 |
| Osaka, F | 1 |
| Kasuga, H | 1 |
| Matsuki, H | 1 |
| Shima, S | 1 |
| Kato, Y | 1 |
| Tron, V | 1 |
| Filipenko, D | 1 |
| Dahlby, R | 1 |
| Okine, LK | 1 |
| Lowe, MC | 1 |
| Mimnaugh, EG | 1 |
| Goochee, JM | 1 |
| Gram, TE | 1 |
| Taylor, RG | 1 |
| McCall, CE | 1 |
| Woodruff, RD | 1 |
| O'Flaherty, JT | 1 |
| Talbot, RJ | 1 |
| Moores, SR | 1 |
| Law, MP | 1 |
| Johannsen, U | 1 |
| Range, U | 1 |
| Bublitz, G | 1 |
| Lindy, S | 2 |
| Kahanpää, K | 2 |
| Karhunen, P | 2 |
| Halme, J | 2 |
| Davis, HV | 1 |
| Reeves, AL | 1 |
| Shafer, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I, Trial to Evaluate the Safety, Tolerability, and Potential Efficacy of Allogeneic Human Mesenchymal Stem Cell (hMSC) Infusion in Patients With Non-Cystic Fibrosis Bronchiectasis[NCT02625246] | Phase 1 | 6 participants (Actual) | Interventional | 2016-02-04 | Completed | ||
| A Phase I, Trial to Evaluate the Safety, Tolerability, and Potential Efficacy of Allogeneic Human Mesenchymal Stem Cell Infusion in Patients With Mild Asthma[NCT03137199] | Phase 1 | 3 participants (Actual) | Interventional | 2017-06-22 | Terminated (stopped due to First cohort completed. Per sponsor decision.) | ||
| Mesenchymal Stem Cell Therapy for Liver Cirrhosis: A Phase I/II Study[NCT03626090] | Phase 1/Phase 2 | 20 participants (Anticipated) | Interventional | 2018-08-18 | Recruiting | ||
| A Trial of Montelukast for Maintenance Therapy of Eosinophilic Esophagitis in Children[NCT01458418] | 4 participants (Actual) | Interventional | 2011-12-31 | Terminated (stopped due to Inability to complete enrollment due to difficulty in finding subjects) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Eosinophils/high powered field(hpf) in the mid esophagus will be measured after 12 weeks of therapy. (NCT01458418)
Timeframe: 12 weeks
| Intervention | Eosinophils/HPF (Mean) |
|---|---|
| Subjects Whose Arm is Unknown Due to Not Being Unblinded | 8 |
3 reviews available for hydroxyproline and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Prevention of collagen deposition following pulmonary oxygen toxicity in the rat by cis-4-hydroxy-L-proline.
Topics: Animals; Collagen; Hydroxyproline; Lung; Lung Volume Measurements; Male; Oxygen; Pressure; Pulmonary | 1980 |
Silica and asbestos: contrasts in tissue response.
Topics: Animals; Asbestos; Asbestosis; Cell Survival; Chick Embryo; Fibroblasts; Guinea Pigs; Humans; Hydrox | 1979 |
The many faces of an increase in lung collagen.
Topics: Animals; Autoradiography; Bleomycin; Butylated Hydroxytoluene; Cell Division; Collagen; Connective T | 1985 |
1 trial available for hydroxyproline and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5.
Topics: Animals; Bleomycin; Bone Marrow; Caspases; Hydrogen Sulfide; Hydroxyproline; Male; Mesenchymal Stem | 2022 |
525 other studies available for hydroxyproline and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Lung; Lung Injury; Mice; Mice, Inb | 2022 |
Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT.
Topics: Animals; Autophagy; Disease Models, Animal; Diterpenes, Kaurane; Hydroxyproline; Inflammation; Lipop | 2022 |
Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL | 2022 |
FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis.
Topics: Animals; beta-N-Acetylhexosaminidases; Fibrosis; Histamine; Hydroxyproline; Immunoglobulin E; Interl | 2022 |
Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways.
Topics: Animals; Fibrosis; Hydroxyproline; Interleukin-18; Janus Kinase 2; Macrophages; Pneumonia; Pulmonary | 2022 |
Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis.
Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Disease Models, Animal; Fibrosis; He | 2022 |
Protective Effect of Combined Moxibustion and Decoction Therapy on Bleomycin-Induced Pulmonary Fibrosis in Rats under Nuclear Factor-κB/Transforming Growth Factor-β1/Smads Signaling Pathway.
Topics: Animals; Bleomycin; Eosine Yellowish-(YS); Glutathione; Hematoxylin; Hydroxyproline; Malondialdehyde | 2022 |
Sunitinib displays pulmonary fibrosis in experimental rats: Role of IL-17A dependent pathway.
Topics: Animals; Collagen; Fibrosis; Hydroxyproline; Interleukin-17; Interleukin-6; Pulmonary Fibrosis; Rats | 2023 |
Tuberostemonine may enhance the function of the SLC7A11/glutamate antiporter to restrain the ferroptosis to alleviate pulmonary fibrosis.
Topics: Amino Acid Transport System y+; Animals; Bleomycin; Collagen; Ferroptosis; Glutamic Acid; Humans; Hy | 2024 |
Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin.
Topics: Animals; Bleomycin; Cells, Cultured; Cytoprotection; Disease Models, Animal; Extracellular Signal-Re | 2019 |
Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Collagen; Doxycycline; Fibroblasts; Gene Expression Regulation; Genot | 2019 |
Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice.
Topics: Animals; Antioxidants; Diosmin; Fibrosis; Glutathione; Hydroxyproline; Lung Injury; Male; Mice; Mice | 2019 |
Effects of thalidomide on Th17, Treg cells and TGF-β1/Smad3 pathway in a mouse model of systemic sclerosis.
Topics: Animals; Cytokines; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Immunosuppressive Agen | 2020 |
Protective effect of rutin against bleomycin induced lung fibrosis: Involvement of TGF-β1/α-SMA/Col I and III pathway.
Topics: Actins; Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Ty | 2020 |
Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation.
Topics: A549 Cells; Astragalus Plant; Bleomycin; Epithelial-Mesenchymal Transition; Humans; Hydroxyproline; | 2020 |
Baicalin alleviates bleomycin‑induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway.
Topics: Animals; Bleomycin; Cell Cycle Checkpoints; Cell Proliferation; Female; Fibroblasts; Flavonoids; Gen | 2020 |
Expression and significance of miR-223 in rats with pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Hydroxyproline; Inflammation; Male; MicroRNAs; Pulmonary Fibrosis; | 2020 |
GLP-1 receptor agonist ameliorates experimental lung fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Arginase; Bleomycin; Collagen; Glucagon-Like Peptide-1 Recepto | 2020 |
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Topics: Administration, Oral; Alkalies; Amino Acid Oxidoreductases; Amino Acids; Animals; Bleomycin; Citrus; | 2021 |
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis.
Topics: Alveolar Epithelial Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cell Polarity; Cellular Senescen | 2021 |
Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis.
Topics: Animals; Cadherins; Collagen; Collagen Type I; Epithelial Cells; Epithelial-Mesenchymal Transition; | 2017 |
Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary fibrosis mice.
Topics: A549 Cells; Animals; Bleomycin; Cell Line; Female; Humans; Hydroxyproline; Inflammation; Interleukin | 2017 |
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway.
Topics: Animals; Bleomycin; Cadherins; Cytokines; Hydroxyproline; Lung; Male; Malondialdehyde; Mice, Inbred | 2017 |
[The Effect of Sodium Ferulate in Experimental Pulmonary Fibrosis via NALP3 Inflammasome].
Topics: Actins; Animals; CARD Signaling Adaptor Proteins; Caspase 1; Collagen Type I; Coumaric Acids; Hydrog | 2017 |
Rosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts.
Topics: Abietanes; Animals; Apoptosis; Bleomycin; Catalase; Cell Cycle; Cell Line; Cell Movement; Cell Proli | 2017 |
Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination | 2018 |
Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice.
Topics: Animals; Blotting, Western; Diosgenin; Epithelial Cells; Female; Flow Cytometry; Hydroxyproline; Imm | 2017 |
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Topics: Airway Remodeling; Animals; beta Catenin; Disease Models, Animal; Female; Hydroxyproline; Interleuki | 2018 |
Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bronchoalveolar Lavage Fluid; Fibrosi | 2018 |
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis.
Topics: Animals; Azepines; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Female; Fibroblasts; Gamma | 2018 |
Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).
Topics: Aniline Compounds; Animals; Hydroxyproline; Imatinib Mesylate; Lung; Mice; Mice, Transgenic; Nitrile | 2018 |
Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication.
Topics: Acute Lung Injury; Animals; Biomarkers; Cyclophosphamide; Cytoprotection; Disease Models, Animal; Dr | 2018 |
Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airway mucus and bleomycin-\
induced pulmonary fibrosis in rats.
Topics: Air Pollutants; Animals; Bleomycin; Collagen; Drugs, Chinese Herbal; Humans; Hydroxyproline; Lung; M | 2016 |
Interleukin-37 Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice.
Topics: Animals; Bleomycin; Collagen; Cytokines; Hydroxyproline; Interleukin-1; Mice; Pneumonia; Pulmonary F | 2018 |
Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis.
Topics: Administration, Oral; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydr | 2018 |
Animal Models of Pulmonary Fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Fluorescein-5-isothiocyanate; Histocytochemistry; Hydrox | 2018 |
Polysaccharides from Dendrobium officinale inhibit bleomycin-induced pulmonary fibrosis via the TGFβ1-Smad2/3 axis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Dendrobium; Epithelial-Mesenchymal Tra | 2018 |
Protective Effects of Nintedanib against Polyhexamethylene Guanidine Phosphate-Induced Lung Fibrosis in Mice.
Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Guanidines; Hydroxyprolin | 2018 |
Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway.
Topics: ADAMTS1 Protein; Animals; Antagomirs; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Collagen | 2018 |
Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Coumaric Acid | 2018 |
A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice.
Topics: Actins; Animals; Antibiotics, Antineoplastic; Bleomycin; Bombyx; Connective Tissue Growth Factor; Di | 2018 |
Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibrosis potentially by attenuating Wnt/β-catenin signaling in rats.
Topics: Animals; beta Catenin; Bone Marrow Cells; Cell Proliferation; Cyclin D1; Epithelial-Mesenchymal Tran | 2018 |
Rosiglitazone attenuates paraquat-induced lung fibrosis in rats in a PPAR gamma-dependent manner.
Topics: Actins; Animals; Aorta, Abdominal; Gene Expression Regulation; Hydroxyproline; Lung; Male; Organ Siz | 2019 |
TGF-β1 mediated MAPK signaling pathway promotes collagen formation induced by Nano NiO in A549 cells.
Topics: A549 Cells; Collagen Type I; Humans; Hydroxyproline; MAP Kinase Signaling System; Mitogen-Activated | 2019 |
Therapeutic effects of the rhSOD2-Hirudin fusion protein on bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Cell Proliferation; Female; Fibroblasts; Gene Expression Regulation; Hir | 2019 |
Epicatechin protective effects on bleomycin-induced pulmonary oxidative stress and fibrosis in mice.
Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Catalase; Catechin; Disease Models, Animal; Glutathion | 2019 |
HIV-1 Protein gp120 Induces Mouse Lung Fibroblast-to-Myofibroblast Transdifferentiation via CXCR4 Activation.
Topics: Actins; Animals; Benzylamines; Cell Transdifferentiation; Cyclams; Female; Fibroblasts; Heterocyclic | 2019 |
Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Anticoagulants; Bleomycin; Dermatan Sulfate; Disease Models, A | 2019 |
Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cell Differentiation; Cells, Cultured; Disease Models | 2019 |
Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition.
Topics: Animals; Autophagy; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Line; Cell Movement; Cell Survival | 2019 |
Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Di | 2013 |
The therapeutic efficacy of glutamine for rats with smoking inhalation injury.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Glutamine; Heme Oxygenase (Decycliz | 2013 |
Astaxanthin ameliorates lung fibrosis in vivo and in vitro by preventing transdifferentiation, inhibiting proliferation, and promoting apoptosis of activated cells.
Topics: Actins; Antigens, CD; Apoptosis; Bleomycin; Blood-Brain Barrier; Cadherins; Cell Line, Tumor; Cell P | 2013 |
Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21.
Topics: Actins; Administration, Oral; Animals; Antioxidants; Bleomycin; Disease Models, Animal; Dose-Respons | 2013 |
Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study.
Topics: Animals; Antimetabolites; Berberine; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Col | 2013 |
Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.
Topics: Animals; Bleomycin; Hydroxyproline; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung Co | 2013 |
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cu | 2013 |
Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN.
Topics: Animals; Dietary Supplements; Docosahexaenoic Acids; Gene Expression Regulation; Hydroxyproline; Lun | 2013 |
Protective effects of methyl palmitate against silica-induced pulmonary fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Cell Count; Hydroxypr | 2013 |
Bone morphogenetic protein-7 inhibits silica-induced pulmonary fibrosis in rats.
Topics: Animals; Bone Morphogenetic Protein 7; Dust; Humans; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; | 2013 |
Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6.
Topics: Alveolar Epithelial Cells; Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar La | 2013 |
[Monoclonal antibody against laminin receptor 1 inhibits the pulmonary fibrosis induced by bleomycin in rats].
Topics: Animals; Antibodies, Monoclonal; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Matr | 2013 |
High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; C-Reactiv | 2013 |
Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice.
Topics: Amiodarone; Animals; Benzylisoquinolines; Body Weight; Cell Count; Hydroxyproline; Interleukin-2 Rec | 2013 |
Evaluating the inhibitory potential of sulindac against the bleomycin-induced pulmonary fibrosis in wistar rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Bleomycin; Body Weigh | 2013 |
Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats.
Topics: Animals; Blotting, Western; Hydroxyproline; Lipid Peroxidation; Lung; Male; Oxidation-Reduction; Oxi | 2013 |
Chronic alcohol ingestion primes the lung for bleomycin-induced fibrosis in mice.
Topics: Actins; Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Differentiation; Central Nervous Syste | 2014 |
Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Cell Proliferation; Disease Models, Animal; Fibroblast | 2013 |
Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors.
Topics: Anilides; Animals; Atorvastatin; Body Weight; Heptanoic Acids; Herbicides; Hydroxyproline; Lung; Mal | 2013 |
Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.
Topics: Adoptive Transfer; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Cell Prol | 2014 |
Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Diff | 2014 |
CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis.
Topics: Actins; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; CCN Intercellular Signaling Proteins; Cell | 2014 |
Atorvastatin attenuates bleomycin-induced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway.
Topics: Animals; Atorvastatin; Bleomycin; Body Weight; Collagen; Connective Tissue Growth Factor; Down-Regul | 2013 |
Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A.
Topics: Animals; Antineoplastic Agents; Antitussive Agents; Bleomycin; Cell Line, Tumor; Cyclic AMP-Dependen | 2014 |
Agmatine attenuates silica-induced pulmonary fibrosis.
Topics: Agmatine; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytoprotection; Disease Models, Animal; | 2014 |
[Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice].
Topics: Actins; Animals; Bleomycin; Calcitriol; Collagen Type I; Disease Models, Animal; Gene Expression Reg | 2013 |
Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.
Topics: Animals; Antibiotics, Antineoplastic; Autocrine Communication; Bleomycin; Blotting, Western; Broncho | 2014 |
The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis.
Topics: Adenoviridae; Animals; Bleomycin; Bone Marrow Cells; Cell Differentiation; Cytokines; Granulocyte-Ma | 2014 |
The effect of adipose stem cell therapy on pulmonary fibrosis induced by repetitive intratracheal bleomycin in mice.
Topics: Adipose Tissue; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; In Situ Nick-End L | 2014 |
The effect of adipose stem cell therapy on pulmonary fibrosis induced by repetitive intratracheal bleomycin in mice.
Topics: Adipose Tissue; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; In Situ Nick-End L | 2014 |
The effect of adipose stem cell therapy on pulmonary fibrosis induced by repetitive intratracheal bleomycin in mice.
Topics: Adipose Tissue; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; In Situ Nick-End L | 2014 |
The effect of adipose stem cell therapy on pulmonary fibrosis induced by repetitive intratracheal bleomycin in mice.
Topics: Adipose Tissue; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; In Situ Nick-End L | 2014 |
Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
Topics: Animals; Bleomycin; Disease Models, Animal; Extracellular Matrix; Hydroxyproline; Inflammation; Lung | 2014 |
The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats.
Topics: Actins; Animals; Antioxidants; Catechin; Dexamethasone; Gamma Rays; Gene Expression; Heme Oxygenase- | 2014 |
The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factors; Extracellular Matrix Proteins; Femal | 2014 |
Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.
Topics: Animals; Benzilates; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Death; Glutathione Tr | 2014 |
Fibrogenesis in granulomas and lung interstitium in tuberculous inflammation in mice.
Topics: Animals; BCG Vaccine; Cell Proliferation; Disease Models, Animal; Fibroblasts; Granuloma; Hydroxypro | 2014 |
Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia.
Topics: Animals; Apoptosis; Butylated Hydroxytoluene; Cell Proliferation; Collagen Type I; Collagen Type II; | 2014 |
Passion fruit peel extract attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Body Weight | 2014 |
[Effect of leptin on lung fibrosis of silicosis rats and the correlation between leptin and HIF-1α expressions].
Topics: Animals; Blotting, Western; Collagen; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Hypoxia-Ind | 2014 |
[The circulating fibrocytes are associated with the lung inflammation and fibrosis of mice with interstitial lung disease].
Topics: Actins; Animals; Arthritis, Experimental; Bleomycin; Collagen Type I; Female; Flow Cytometry; Hydrox | 2014 |
Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-κB in mice.
Topics: Actins; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar L | 2014 |
Arsenic trioxide prevents rat pulmonary fibrosis via miR-98 overexpression.
Topics: Actins; Animals; Arsenic Trioxide; Arsenicals; Bleomycin; Cadherins; Collagen Type I; Down-Regulatio | 2014 |
Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen abnormal deposition in rats.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Collagen Type I; Disease Models, Animal; Drugs, Chine | 2014 |
Losartan attenuates paraquat-induced pulmonary fibrosis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Collagen; Herbicides; Hydroxypr | 2015 |
Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Elapid Venoms; Elapidae; Female; Fibrosi | 2014 |
Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.
Topics: Animals; Bleomycin; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Disease Model | 2016 |
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis.
Topics: Actins; Animals; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Dioxoles; Disease Models, | 2015 |
Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Actins; Animals; Bleomycin; Collagen Type I; Disease Models, Animal; Drugs, Chinese Herbal; Female; | 2015 |
Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Collagen; Extracellular Signal-Regulated MAP Kinases; | 2015 |
Protective roles of pulmonary rehabilitation mixture in experimental pulmonary fibrosis in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Blotting, Western; Cells, Cultured; Coll | 2015 |
Cyclophosphamide Combined with Bone Marrow Mesenchymal Stromal Cells Protects against Bleomycin-induced Lung Fibrosis in Mice.
Topics: Animals; Biological Assay; Bleomycin; Cell Differentiation; Chemokine CXCL12; Collagen; Combined Mod | 2015 |
Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Collagen; Cytokines; Cytoprotection | 2015 |
High-Mobility Group Box 1 Mediates Epithelial-to-Mesenchymal Transition in Pulmonary Fibrosis Involving Transforming Growth Factor-β1/Smad2/3 Signaling.
Topics: Actins; Animals; Cadherins; Cell Line; Cell Line, Tumor; Collagen Type I; Epithelial Cells; Epitheli | 2015 |
An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Disease Models, Animal; Endostati | 2015 |
Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling.
Topics: Animals; Bleomycin; Bone Marrow Cells; Collagen; Gene Expression Regulation; Humans; Hydroxyproline; | 2015 |
Role of thioredoxin nitration in bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; L | 2016 |
Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Cyclooxygenase 2; Eclipta; Hydroxyproline; Lung; Male; Malondialdehyde; | 2015 |
Total glycosides of Yupingfeng protects against bleomycin-induced pulmonary fibrosis in rats associated with reduced high mobility group box 1 activation and epithelial-mesenchymal transition.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Dose-Response Relationship, Drug; Drugs, Chinese Herba | 2015 |
Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Epithelial Cells; Gene Expression Profiling; Humans; Hyd | 2015 |
Protective effect of gallic acid against bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Cytokines; Dose-Response Relationship, Drug; Gallic Ac | 2015 |
Effect of roflumilast on airway remodelling in a murine model of chronic asthma.
Topics: Airway Remodeling; Allergens; Aminopyridines; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Br | 2016 |
Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Collectins; Cytokines; Disease Models, A | 2015 |
Preventive effects of vitamin D treatment on bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Dietary Supplements; Fibrin; Hydroxyproline; Male; Mice; Pulmonary Fibrosis; Vit | 2015 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleu | 2015 |
Therapeutic advantage of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmonary fibrosis mouse model.
Topics: Administration, Inhalation; Albumins; Animals; Antimetabolites; Bleomycin; Chemistry, Pharmaceutical | 2016 |
Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice.
Topics: Actins; Animals; Bleomycin; Chalcone; Collagen Type I; Connective Tissue Growth Factor; Epithelial-M | 2016 |
[Effect of radiation dose and dose rate on pulmonary fibrosis in mice].
Topics: Animals; Collagen Type I; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Radiat | 2016 |
Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model.
Topics: Alveolar Epithelial Cells; Animals; Cell Proliferation; Cellular Senescence; Collagen; Cytokines; Fe | 2016 |
Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles.
Topics: Administration, Inhalation; Aerosols; Animals; Bleomycin; Chitosan; Collagen; Hydroxyproline; Imagin | 2016 |
The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Body Weight; Dose-Response Relationsh | 2016 |
Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung.
Topics: Actins; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Connecti | 2016 |
Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9.
Topics: Amides; Animals; Antioxidants; Biomarkers; Bleomycin; Cytoprotection; Disease Models, Animal; Dose-R | 2016 |
Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Berberis; Chromatography, Thin Layer; Fruit; Hydroxyproline; Inflammation Mediators; Interl | 2016 |
Protective roles of polysaccharides from Ganoderma lucidum on bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Body Weight; Catalase; Glutathione; Glutathione Peroxidase; Hydroxyproline; Lung | 2016 |
Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of Caveolin-1 and TGF-β1 Signal Pathway.
Topics: Actins; Animals; Bleomycin; Caveolin 1; Ginsenosides; Hydroxyproline; Lung; Male; Protective Agents; | 2016 |
Amelioration of bleomycin-induced lung fibrosis in rats by valproic acid and butyrate: Role of nuclear factor kappa-B, proinflammatory cytokines and oxidative stress.
Topics: Animals; Bleomycin; Butyrates; Cytokines; Drug Synergism; Drug Therapy; Drug Therapy, Combination; D | 2016 |
Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.
Topics: Alveolar Epithelial Cells; Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Line; Cell Prolifer | 2016 |
HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway.
Topics: Actins; Animals; Biomarkers; Bleomycin; Fibroblasts; Hydroxyproline; Inflammation Mediators; Isoquin | 2017 |
Long-term treatment with royal jelly improves bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Dose-Response Relationship, Drug; Fatty | 2017 |
Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis.
Topics: Animals; Aquaporin 5; Blotting, Western; Bone Morphogenetic Protein 7; Bronchoalveolar Lavage Fluid; | 2017 |
Comparative Proteomic Analysis of Bleomycin-induced Pulmonary Fibrosis Based on Isobaric Tag for Quantitation.
Topics: Animals; Bleomycin; Chromatography, Liquid; Cytochrome P-450 CYP1A1; Hydroxyproline; Lung; Male; Pro | 2017 |
Effects of prolonged methylprednisolone treatment after pulse therapy for paraquat-intoxicated rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Glucocorticoids; Herbicides; Hydroxyproline; M | 2018 |
Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis.
Topics: Animals; Disease Models, Animal; Disease Progression; Hydroxyproline; Imaging, Three-Dimensional; Ma | 2017 |
Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis.
Topics: Administration, Inhalation; Animals; Bleomycin; Fibroblasts; Hydroxyproline; Male; Mice; Mice, Inbre | 2017 |
Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Collagen; Glutathione; Glutathione Reductase | 2009 |
A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Lung; Male; Malondialdehyde; Oxidativ | 2008 |
A TSP-1 synthetic peptide inhibits bleomycin-induced lung fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; I | 2009 |
Attenuation effects of heparin-superoxide dismutase conjugate on bleomycin-induced lung fibrosis in vivo and radiation-induced inflammatory cytokine expression in vitro.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression; Heparin; | 2009 |
Biphasic effects of free radical scavengers against bleomycin-induced pulmonary fibrosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antipyrine; Apoptosis; Bleomycin; Bronchi; Bronchoalveolar Lav | 2008 |
Attenuation of bleomycin-induced lung fibrosis by oxymatrine is associated with regulation of fibroblast proliferation and collagen production in primary culture.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cell Proliferation; Cells, C | 2008 |
Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Arylsulfonates; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Cytokines; Female; | 2009 |
[Effects of curcumin on bleomycin-induced damages in pulmonary functions in rats].
Topics: Animals; Bleomycin; Curcumin; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Time Factors | 2008 |
VEGFR-2 antagonist SU5416 attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Bleomycin; Blotting, Western; Broncho | 2009 |
Notch1 signaling in FIZZ1 induction of myofibroblast differentiation.
Topics: Actins; Animals; Antibiotics, Antineoplastic; Basic Helix-Loop-Helix Transcription Factors; Bleomyci | 2009 |
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Bone Marrow Cells; Chondrocytes; | 2009 |
Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Diet; Hyaluronic Acid; Hydroxyproline; | 2009 |
Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Bronch | 2009 |
Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Western; Enzyme Inhibitors; Enzyme-Li | 2009 |
The anti-fibrotic agent SMP-534 attenuates bleomycin-induced pulmonary fibrosis in hamsters.
Topics: Animals; Antibiotics, Antineoplastic; Benzamides; Bleomycin; Body Weight; Cricetinae; Cricetulus; Ex | 2009 |
Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice.
Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Hydroxy | 2010 |
Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis.
Topics: Animals; Bleomycin; Body Weight; Cell Survival; Cells, Cultured; Citrus; Disease Models, Animal; Dru | 2009 |
Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid | 2009 |
Extracorporeal photopheresis in a rat model of pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation | 2009 |
Pulmonary fibrosis induced by H5N1 viral infection in mice.
Topics: Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Influenza A Virus, H5N1 S | 2009 |
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis.
Topics: Animals; Benzylisoquinolines; Bleomycin; Cell Line; Cell Proliferation; Cytokines; Endothelin-1; Gen | 2010 |
Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Caspase 3; Caspase 9; Cell Line; Chemot | 2009 |
A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Bleomycin; Bronchoalveolar Lavage Fluid; Cytoki | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation | 2010 |
Induction of EMT-like phenotypes by an active metabolite of leflunomide and its contribution to pulmonary fibrosis.
Topics: Aniline Compounds; Animals; Bleomycin; Cells, Cultured; Crotonates; Dihydroorotate Dehydrogenase; En | 2010 |
IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Colorimetry; Cytokines; Enzyme-Linked Immunosorbent Assay; Fe | 2010 |
Mizoribine protects against bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Prol | 2010 |
Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Disease Prog | 2010 |
A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis.
Topics: Animals; Bleomycin; Cytokines; Gene Expression Regulation; Hydroxyproline; Inflammation; Liposomes; | 2010 |
Effect of an immunotoxin to folate receptor beta on bleomycin-induced experimental pulmonary fibrosis.
Topics: ADP Ribose Transferases; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, M | 2010 |
Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bleomycin; Blotting, Western; Bronchoalveolar | 2010 |
Effects of erlotinib on lung injury induced by intratracheal administration of bleomycin (BLM) in rats.
Topics: Animals; Bleomycin; Dogs; Erlotinib Hydrochloride; Humans; Hydroxyproline; Injections; Lung; Lung In | 2010 |
Protective effects of a bacterially expressed NIF-KGF fusion protein against bleomycin-induced acute lung injury in mice.
Topics: Acute Lung Injury; Amino Acid Sequence; Animals; Base Sequence; Bleomycin; Blotting, Western; Cell A | 2010 |
Gender influences the response to experimental silica-induced lung fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Estrogen Receptor alpha; Female; Humans; Hydroxypr | 2010 |
Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.
Topics: Animals; Apoptosis; Blood Cell Count; Bone Marrow; Cell Survival; Cells, Cultured; Disease Models, A | 2010 |
Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice.
Topics: Acetates; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cyclopropanes; Cytokines; Fe | 2011 |
Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat?
Topics: Animals; Antidotes; Antipyrine; Bronchoalveolar Lavage Fluid; Edaravone; Herbicides; Hydroxyproline; | 2011 |
Beneficial effects of early (but not late) intervention of heme oxygenase-1 on bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Glutathione; Heme Oxygenase-1; Hemin; Hydroxyproline; Lactate Dehydrogenases; Lu | 2011 |
[Pirfenidone diminishes SiO2 induced lung fibrosis in rats].
Topics: Animals; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Pyridones; Rats; Rats, Sprague-Dawley; Sili | 2010 |
The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Chemokines, CC; Chymases; Cytokines; Hydroxyp | 2011 |
[Baicalin prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats].
Topics: Animals; Bleomycin; Connective Tissue Growth Factor; Flavonoids; Hydroxyproline; Male; Pulmonary Fib | 2010 |
A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Connective Tissue Growth Factor; Hydroxypr | 2011 |
Effect of leukotriene receptor antagonists on lung fibrosis in rats.
Topics: Acetates; Animals; Bleomycin; Collagen; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combin | 2011 |
Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.
Topics: Analysis of Variance; Animals; Apoptosis; Bleomycin; Cell Proliferation; DNA Primers; Epithelial Cel | 2011 |
(Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a novel readily available and orally active glitazone, attenuates the bleomycin-induced pulmonary fibrosis in vivo.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Line; Collagen; Cytokines; Dose-Response Rela | 2011 |
Inhibitory effect of safflor yellow on pulmonary fibrosis.
Topics: Actins; Animals; Bleomycin; Carthamus tinctorius; Cell Differentiation; Dose-Response Relationship, | 2011 |
A novel method for accurate collagen and biochemical assessment of pulmonary tissue utilizing one animal.
Topics: Analysis of Variance; Animals; Asbestos, Crocidolite; Asbestosis; Azo Compounds; Biomarkers; Collage | 2011 |
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Humans; Hydroxyp | 2011 |
Assessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Body Temperature; Body Weight; Disease Models, Anim | 2012 |
Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis.
Topics: Animals; Annexin A1; Biomimetic Materials; Bleomycin; Cytokines; Disease Models, Animal; Epithelial | 2011 |
The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; CD4-Positive T-Lymphocytes; Cell Count; Disease Mod | 2012 |
In vivo and in vitro lung mechanics by forced oscillations: effect of bleomycin challenge.
Topics: Airway Resistance; Animals; Antibiotics, Antineoplastic; Bleomycin; Elasticity; Extravascular Lung W | 2012 |
Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chromones; Cytokines; Disease Progression; Female; Hydroxypro | 2012 |
The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine.
Topics: Animals; Antioxidants; Bleomycin; Grape Seed Extract; Hydroxyproline; Inflammation; Lung; Lymphocyte | 2012 |
Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis.
Topics: Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage; Case-Control Studies; Collagen; Enzyme-Linke | 2012 |
Induction of pulmonary fibrosis by cerium oxide nanoparticles.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cerium; Dose-Response Relationship, Drug; Hydroxyproline; Lun | 2012 |
siRNA against plasminogen activator inhibitor-1 ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Actins; Animals; Apoptosis; Bleomycin; Caspase 3; Cells, Cultured; Collagen; Fibroblasts; Hydroxypro | 2012 |
Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fl | 2012 |
Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Bronchoalveolar Lavage; Cytokines; Drinking Wat | 2012 |
[Blocking IL-17A protects against lung injury-induced pulmonary fibrosis through promoting the activation of p50NF-kappaB].
Topics: Acute Lung Injury; Animals; Bleomycin; Collagen; Hydroxyproline; Interleukin-13; Interleukin-17; Mal | 2012 |
The effect of octreotide, an analog of somatostatin, on bleomycin-induced interstitial pulmonary fibrosis in rats.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Gastrointestinal Agents; Hydroxyproline; Injections | 2013 |
Thymoquinone blocks lung injury and fibrosis by attenuating bleomycin-induced oxidative stress and activation of nuclear factor Kappa-B in rats.
Topics: Animals; Antioxidants; Benzoquinones; Bleomycin; Glutathione Transferase; Hydroxyproline; L-Lactate | 2012 |
Altered microRNAs expression profiling in experimental silicosis rats.
Topics: Animals; Ceruloplasmin; Disease Models, Animal; Hydroxyproline; Lung; Male; Microarray Analysis; Mic | 2012 |
Inhibitory effects of alkaline extract of Citrus reticulata on pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Cell Line; Cell Proliferation; Citrus; Humans; Hydroxy | 2013 |
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Collagen; Everolimus; Hydroxyproline; Immunosup | 2002 |
Halofuginone does not reduce fibrosis in bleomycin-induced lung injury.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Northern; Br | 2002 |
Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains.
Topics: Adenoviridae; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Collagen; Female; Fibroblasts; Gene | 2002 |
Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorben | 2002 |
Effects of delayed treatment with transforming growth factor-beta soluble receptor in a three-dose bleomycin model of lung fibrosis in hamsters.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cricetina | 2002 |
The role of sodium cromolyn in treatment of paraquat-induced pulmonary fibrosis in rat.
Topics: Animals; Anti-Asthmatic Agents; Collagen; Cromolyn Sodium; Female; Hydroxyproline; Lung; Organ Size; | 2002 |
Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Guanidines; Hy | 2002 |
Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Interleukin-4; Lung; Male; Mice; M | 2002 |
Time course of bleomycin-induced lung fibrosis.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Hydro | 2002 |
[The mechanisms and effects of panax notoginside and methylprednisolone in a rat model of pulmonary fibrosis].
Topics: Animals; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Collagen; Disease Models, Animal; Hydroxypr | 2002 |
Murine gammaherpes virus as a cofactor in the development of pulmonary fibrosis in bleomycin resistant mice.
Topics: Animals; Bleomycin; Chromatography, High Pressure Liquid; Collagen; Drug Resistance; Gammaherpesviri | 2002 |
Airway wall remodeling induced by occupational mineral dusts and air pollutant particles.
Topics: Air Pollutants; Air Pollutants, Occupational; Animals; Asbestos, Amosite; Collagen Type I; Drug Syne | 2002 |
Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Cricetinae; Diet; DNA Probes; Gene Expres | 2003 |
Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Bleomycin; Body Weight; Ceruloplasmin; Disea | 2003 |
Pulmonary toxicity of thuringiensin administered intratracheally in Sprague-Dawley rats.
Topics: Adenosine; Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Fibronec | 2003 |
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats.
Topics: Acetonitriles; Acetylcysteine; Animals; Antioxidants; Biomarkers; Bleomycin; Bronchoalveolar Lavage | 2003 |
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Cytokines; Disease Model | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.
Topics: Animals; Bleomycin; Bone Marrow Transplantation; Collagen; Drug Resistance; Enzyme Induction; Female | 2003 |
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2003 |
Cigarette smoke exposure potentiates bleomycin-induced lung fibrosis in guinea pigs.
Topics: Actins; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Division; Environmental Exposure; Fib | 2003 |
Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis.
Topics: Animals; Apoptosis; Base Sequence; Biomarkers; Blotting, Northern; Collagenases; Disease Models, Ani | 2003 |
The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis.
Topics: Animals; Base Sequence; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2003 |
Involvement of mast cell chymase in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Bleomycin; Chymases; Dose-Response Relation | 2003 |
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Extracell | 2003 |
Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Caffeic Acids; Catalase; Hydroxyproline; Lung; Male; Malondialdehy | 2004 |
Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist.
Topics: Albumins; Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Benzimidazo | 2004 |
Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.
Topics: Animals; Granuloma; Hydroxyproline; Hypersensitivity, Delayed; Inflammation; Interferon-gamma; Inter | 2004 |
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Topics: Actins; Allergens; Animals; Antibodies; Asthma; Bronchi; Chemotaxis, Leukocyte; Collagen; Disease Mo | 2004 |
Induction of CDK inhibitor p21 gene as a new therapeutic strategy against pulmonary fibrosis.
Topics: Adenoviridae; Animals; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epithelial Cells; Gene Expres | 2004 |
Skeletal muscle targeting in vivo electroporation-mediated HGF gene therapy of bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Apoptosis; Bleomycin; Electroporation; Genetic Therapy; Hepatocyte Growth Factor; Hydroxypr | 2004 |
The transcription factor NRF2 protects against pulmonary fibrosis.
Topics: Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Division; Collagen; Enzyme Induct | 2004 |
[Study on the injury effect of ammonium perchlorate to lung].
Topics: Animals; Bronchoalveolar Lavage Fluid; Female; Hydroxyproline; Lung; Malondialdehyde; Perchlorates; | 2004 |
Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Glutathione Peroxidase; Hydroxyprolin | 2004 |
C-type natriuretic peptide attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Hydroxyproline; Infusions, Parenteral; Int | 2004 |
Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Bleomycin; Disease Models, Animal; HSP70 Heat-Shock P | 2004 |
C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
Topics: Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked | 2004 |
[The dynamic changes of collagen fiber in quartz-induced pulmonary fibrosis in mice with picrosirius red plus polarized microscopy in vivo].
Topics: Animals; Azo Compounds; Collagen Type I; Collagen Type III; Coloring Agents; Hydroxyproline; Lung; M | 2004 |
Effect of Feitai on bleomycin-induced pulmonary fibrosis in rats.
Topics: Administration, Oral; Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage; Cell Line; Cell Proli | 2005 |
Carbon monoxide suppresses bleomycin-induced lung fibrosis.
Topics: Animals; Bleomycin; Carbon Monoxide; Cell Cycle; Cell Division; Cyclic AMP; Cyclic GMP; Hydroxyproli | 2005 |
Antifibrotic effect of interferon gamma in silicosis model of rat.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Immunohistochemistry; Interferon-gamma; Int | 2005 |
[Influence of compound biejia ruangan prescription on extracelluar matrix in bleomycin induced pulmonary fibrosis rats].
Topics: Animals; Bleomycin; Collagen Type III; Collagen Type IV; Drug Combinations; Drugs, Chinese Herbal; H | 2004 |
Attenuation of bleomycin-induced lung fibrosis in rats by mesna.
Topics: Animals; Bleomycin; Drug Administration Schedule; Drug Screening Assays, Antitumor; Glutathione; Hyd | 2005 |
Protection against bleomycin-induced lung injury by IL-18 in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Granulocyte-M | 2005 |
Comparing study of the effect of nanosized silicon dioxide and microsized silicon dioxide on fibrogenesis in rats.
Topics: Animals; Female; Hydroxyproline; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Inhal | 2004 |
[A preliminary study of CTGF in bleomycin-induced mouse pulmonary fibrosis].
Topics: Animals; Biomarkers; Bleomycin; Connective Tissue Growth Factor; Gene Expression Regulation; Hydroxy | 2005 |
[Action of EM703 on bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Erythromycin; | 2004 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxy | 2005 |
Effect of IL-2-Bax, a novel interleukin-2-receptor-targeted chimeric protein, on bleomycin lung injury.
Topics: Animals; Apoptosis; Bacterial Toxins; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Genetic E | 2005 |
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
Topics: Animals; Bleomycin; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Disease Models | 2005 |
Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma.
Topics: Adoptive Transfer; Animals; Bleomycin; Body Weight; Cells, Cultured; Disease Models, Animal; Hydroxy | 2005 |
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.
Topics: Animals; Apoptosis; Bleomycin; Cells; Collagen; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2005 |
Preventive effect of melatonin on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproli | 2006 |
Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice.
Topics: Animals; Collagen; Cytokines; Fluorescent Antibody Technique; Forensic Pathology; Gene Expression; G | 2006 |
Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Bleomycin; Body Weigh | 2006 |
EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts.
Topics: Animals; Anti-Inflammatory Agents; Base Sequence; Bleomycin; Cell Line; Cell Proliferation; Collagen | 2006 |
Feitai, a Chinese herbal medicine, reduces transforming growth factor-beta1 and monocyte chemoattractant protein-1 expression in bleomycin-induced lung fibrosis in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Cell Differentiation; Chemokine CCL2; Drugs, Chinese Herb | 2005 |
Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Gi | 2006 |
Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis.
Topics: Animals; Antithrombin III; Bleomycin; Blood Pressure; Body Temperature; Bronchoalveolar Lavage Fluid | 2006 |
S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Cysteine; Enzyme Precursors; Glutathion | 2006 |
[Inhibition of pulmonary fibrosis by doxycycline: an experiment with mice].
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Cell Line, Tumor; Collagenases; Doxycycline; Humans; Hydr | 2006 |
[Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats].
Topics: Animals; Bleomycin; Body Weight; Collagen Type III; Collagen Type IV; Curcuma; Curcumin; Drugs, Chin | 2006 |
Novel pirfenidone analogues: synthesis of pyridin-2-ones for the treatment of pulmonary fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspart | 2006 |
[Kinetics and mechanism in bleomycin-induced murine pulmonary fibrosis model].
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Lung; Male | 2006 |
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.
Topics: Administration, Inhalation; Animals; Collagen; Cytokines; Disease Models, Animal; Hydroxyproline; In | 2006 |
Therapeutic effect of Chinese medicine formula DSQRL on experimental pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Collagen; Disease Models, Animal; Drugs | 2007 |
Low dose pirfenidone suppresses transforming growth factor beta-1 and tissue inhibitor of metalloproteinase-1, and protects rats from lung fibrosis induced by bleomycina.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Dose-Response Relationship, Drug; Hydro | 2006 |
Immunomodulation of experimental pulmonary fibrosis by intravenous immunoglobulin (IVIG).
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen Type I; Hydroxyproline; Immunoglobulins, I | 2006 |
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.
Topics: Actins; Animals; Bleomycin; Caveolin 1; Collagen Type I; Epithelial Cells; Extracellular Matrix; Fib | 2006 |
Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats.
Topics: Administration, Oral; Animals; Bleomycin; Body Weight; Disease Models, Animal; Dose-Response Relatio | 2007 |
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.
Topics: Animals; Antigens, Viral; Arginase; beta-N-Acetylhexosaminidases; Biomarkers; Bronchoalveolar Lavage | 2007 |
Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
Topics: Adoptive Transfer; Animals; Antibodies, Monoclonal; Chemokine CCL21; Chemokines, CC; Cytokines; Extr | 2007 |
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; | 2007 |
[Effect of imatinib mesylate on bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Becaplermin; Benzamides; Bleomycin; Disease Models, Animal; Hydroxyproline; Imatinib Mesyla | 2007 |
ST2 gene induced by type 2 helper T cell (Th2) and proinflammatory cytokine stimuli may modulate lung injury and fibrosis.
Topics: Animals; Cell Line; Cytokines; Drug Combinations; Epithelium; Female; Fibroblasts; Gene Expression R | 2007 |
Anti-fibrotic effect of meloxicam in a murine lung fibrosis model.
Topics: Animals; Antioxidants; Bleomycin; Collagen; Cyclooxygenase Inhibitors; Disease Models, Animal; Gluta | 2007 |
Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Gene Expression Profiling; Glutathio | 2007 |
Influence of early neutrophil depletion on MMPs/TIMP-1 balance in bleomycin-induced lung fibrosis.
Topics: Animals; Antilymphocyte Serum; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Hydroxyproline; Im | 2007 |
[Experimental study on effect of Huaxian Decoction treating bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Drugs, Chinese Herbal; Hydroxyproline; Male; Mice; | 2007 |
An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination; Herbicides; HSP | 2007 |
Complex regulation of pulmonary inflammation and fibrosis by CCL18.
Topics: Adenoviridae; Animals; Antibiotics, Antineoplastic; Antigens, CD; Bleomycin; Cells, Cultured; Chemok | 2007 |
Protective effect of Houttuynia cordata extract on bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Catalase; Drugs, Chin | 2007 |
[Effects of Fuzheng Huayu recipe on MMP-2 activity and type IV collagen expression at fibrotic lung].
Topics: Animals; Bleomycin; Collagen Type IV; Drug Combinations; Drugs, Chinese Herbal; Hydroxyproline; Lung | 2007 |
Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Gene Expression; Humans; Hy | 2007 |
Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in mice.
Topics: 2-Methoxyestradiol; Airway Resistance; Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid | 2007 |
Effect of intramuscular injection of hepatocyte growth factor plasmid DNA with electroporation on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Bleomycin; Cyclooxygenase 2; Electroporation; Genetic Therapy; Hepatocyte Growth Factor; Hy | 2007 |
Inflammatory related changes in lung tissue mechanics after bleomycin-induced lung injury.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Elasticity; Extravascular Lung Water; Hydroxyprolin | 2008 |
Preventive effect of hochu-ekki-to, a Japanese herbal medicine, on bleomycin-induced lung injury in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Drugs, Chinese Herbal | 2007 |
[Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model].
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Paraquat; Placenta Growth Factor; Pre | 2007 |
Simultaneous determination of 3-nitrotyrosine, tyrosine, hydroxyproline and proline in exhaled breath condensate by hydrophilic interaction liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Adult; Breath Tests; Chromatography, Liquid; Female; Humans; Hydroxyproline; Male; Middle Aged; Prol | 2007 |
The role of collagenases in experimental pulmonary fibrosis.
Topics: Administration, Oral; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagenases; Gelatin; Hydro | 2008 |
[Effect of losartan on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Huma | 2007 |
Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Body Weight; Cluster Analysis; Collagen; Disease M | 2007 |
[Effects of cordyceps sinensi on bleomycin-induced pulmonary fibrosis in mice].
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cordyceps; Hydroxyproline; Interferon-gamma; Inter | 2007 |
Comparison between conventional and "clinical" assessment of experimental lung fibrosis.
Topics: Adenoviridae; Animals; Collagen; Disease Models, Animal; Disease Progression; Female; Gene Transfer | 2008 |
In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
Topics: Animals; Bleomycin; Boronic Acids; Bortezomib; Cells, Cultured; Collagen Type I; Fibrosis; Hydroxypr | 2008 |
Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bleomycin | 2008 |
[Comparative fibrogenicity of carbon fibers and asbestos].
Topics: Acrylic Resins; Animals; Asbestos; Asbestos, Serpentine; Carbon; Dust; Hydroxyproline; Lung; Pulmona | 1984 |
Bleomycin-induced pulmonary fibrosis in rats: biochemical demonstration of increased rate of collagen synthesis.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; In Vitro Techniques; Lung; Male; Proline; Pulmonary Fi | 1980 |
Collagen biosynthesis in bleomycin-induced pulmonary fibrosis in hamsters.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Culture Techniques; Hydroxyproline; Lung; Procollagen-Prol | 1980 |
Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Hydroxyproline; Lung; Lung Volume Measurements; Male; Meso | 1981 |
Collagen lysyl oxidase activity in the lung increases during bleomycin-induced lung fibrosis.
Topics: Amino Acid Oxidoreductases; Animals; Bleomycin; Desmosine; Hydroxyproline; Lung; Male; Protein-Lysin | 1981 |
Hyperoxia, but not thoracic X-irradiation, potentiates bleomycin- and cyclophosphamide-induced lung damage in mice.
Topics: Animals; Bleomycin; Collagen; Cyclophosphamide; DNA; Hydroxyproline; Male; Mice; Mice, Inbred BALB C | 1982 |
Effect of the beige mutation on bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Collagen; Cytochalasin B; Dose-Response Relationship, Drug; Female; Hydroxyproli | 1983 |
The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis. A biochemical evaluation.
Topics: Animals; Bleomycin; Collagen; Female; Hydroxyproline; Immunity, Cellular; Lung; Mice; Mice, Nude; Mu | 1983 |
Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity.
Topics: Animals; Bleomycin; Cysteine Endopeptidases; Glycoside Hydrolases; Hydroxyproline; Lung; Mice; Pulmo | 1983 |
Protein metabolism during bleomycin-induced pulmonary fibrosis in rabbits. In vivo evidence for collagen accumulation because of increased synthesis and decreased degradation of the newly synthesized collagen.
Topics: Animals; Bleomycin; Collagen; DNA; Free Radicals; Hydroxyproline; Lung; Proteins; Pulmonary Fibrosis | 1983 |
Peplomycin sulfate and pulmonary fibrosis: hydroxyproline, uronic acid, proline hydroxylase and glucosamine 6-phosphate synthetase in lungs of hamsters treated with peplomycin.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Carbohydrate Epimerases; Cricetinae; Glutamine-Fructose-6 | 1983 |
Fibrogenic structure-activity study of the bleomycin molecule.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Lung; Male; Polyamines; Pulmonary Fibrosis; Rats; Rats | 1983 |
Increases in lung prolyl hydroxylase and superoxide dismutase activities during bleomycin-induced lung fibrosis in hamsters.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Hydroxyproline; Lung; Male; Mesocricetus; Procollagen-Prol | 1983 |
[Comparative studies on fibrogenic properties of diatomites and other silica dusts].
Topics: Animals; Dust; Hydroxyproline; Lipid Metabolism; Lung; Organ Size; Pneumoconiosis; Pulmonary Fibrosi | 1983 |
Enhanced acute lung damage following corticosteroid treatment.
Topics: Acute Disease; Animals; Butylated Hydroxytoluene; DNA; Hydroxyproline; Lung; Lung Diseases; Male; Me | 1984 |
Effect of proline analogs on oxygen toxicity-induced pulmonary fibrosis in the rat.
Topics: Animals; Azetidinecarboxylic Acid; Desmosine; Elastin; Hydroxyproline; Male; Organ Size; Oxygen; Pro | 1984 |
Potentiation of butylated-hydroxytoluene-induced acute lung damage by oxygen. Effects of prednisolone and indomethacin.
Topics: Animals; Butylated Hydroxytoluene; Hydroxyproline; Indomethacin; Lung; Male; Mice; Mice, Inbred BALB | 1983 |
Collagen accumulation in irradiated rat lung: modification by D-penicillamine.
Topics: Animals; Cobalt Radioisotopes; Collagen; Gamma Rays; Hydroxyproline; Lung; Male; Penicillamine; Pulm | 1983 |
[Dynamics of fibrosis formation in the lungs in tuberculosis patients].
Topics: Adult; Female; Humans; Hydroxyproline; Male; Middle Aged; Pulmonary Fibrosis; Time Factors; Tubercul | 1983 |
Endothelial injury and repair in radiation-induced pulmonary fibrosis.
Topics: Animals; Cell Division; Connective Tissue; DNA; Endothelium; Hydroxyproline; Lung; Male; Mice; Pulmo | 1983 |
Long-term morphologic and biochemical features of experimentally induced lung fibrosis in the mouse.
Topics: Animals; Butylated Hydroxytoluene; Collagen; Histocytochemistry; Hydroxyproline; Male; Mice; Mice, I | 1982 |
[Investigations for the quantitative detection of pulmonary fibrosis as late damages following the effects of fast neutron and 60Co-gamma-radiation (author's transl)].
Topics: Animals; Cobalt Radioisotopes; Collagen; Fast Neutrons; Hydroxyproline; Mice; Mice, Inbred C3H; Neut | 1980 |
The effect of indomethacin, prednisolone and cis-4-hydroxyproline on pulmonary fibrosis produced by butylated hydroxytoluene and oxygen.
Topics: Animals; Butylated Hydroxytoluene; Collagen; Hydroxyproline; Indomethacin; Male; Mice; Mice, Inbred | 1981 |
Potentiation of chemically induced lung fibrosis by thorax irradiation.
Topics: Animals; Butylated Hydroxytoluene; Cell Division; Hydroxyproline; Lung; Male; Mice; Pulmonary Fibros | 1980 |
A pathogenetic mechanism in lung fibrosis.
Topics: Animals; Butylated Hydroxytoluene; Histocytochemistry; Hydroxyproline; Lung; Male; Mice; Mice, Inbre | 1980 |
[Biological and histological changes induced by cement dust].
Topics: Animals; Asbestos; Asbestosis; Hydroxyproline; Lung; Pulmonary Fibrosis; Rats | 1980 |
Suppressive effect of anti-alpha 1-antichymotrypsin serum on pulmonary fibrosis induced by phorbol myristate acetate in vivo.
Topics: alpha 1-Antichymotrypsin; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Cells, Cultured; Co | 1995 |
Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice.
Topics: Animals; Antibodies; Bleomycin; Collagen; Hydroxyproline; Immunoglobulin G; Lung; Male; Mice; Pulmon | 1993 |
Experimental study of the effect of IH764-3 on pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Drugs, Chinese Herbal; Fibroblast Growt | 1993 |
Effects of the 21-aminosteroid, U74389F, on bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Elastin; Hydroxyproline; Lipid Peroxidation; Lung; Male; Pregnatri | 1994 |
Mesothelial cell proliferation: a nonspecific response to lung injury associated with fibrosis.
Topics: Animals; Asbestos, Crocidolite; Autoradiography; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Divis | 1994 |
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice.
Topics: Animals; Bleomycin; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pulmonar | 1994 |
Liposome encapsulation improves the effect of antifibrotic agent in rat lung fibrosis.
Topics: Animals; Bleomycin; Drug Carriers; Drug Evaluation, Preclinical; Hydroxyproline; Liposomes; Lung; Or | 1994 |
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL4; Cytokines; Enzyme-Linked Immunosor | 1994 |
Dose and regimen effects of poly ICLC, an interferon inducer, in a multi-dose bleomycin model of interstitial pulmonary fibrosis.
Topics: Animals; Bleomycin; Carboxymethylcellulose Sodium; Cricetinae; Disease Models, Animal; Dose-Response | 1994 |
Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Diet; Hydroxyproline; Lung; | 1994 |
[Effects of tanshionone to bleomycin induced pulmonary fibrosis of rats on histological changes and production of lipid peroxides and hydroxyproline].
Topics: Animals; Bleomycin; Drugs, Chinese Herbal; Female; Hydroxyproline; Lipid Peroxides; Lung; Male; Phen | 1994 |
Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters.
Topics: Analysis of Variance; Animals; Bleomycin; Body Weight; Cricetinae; Diet; Hydroxyproline; Lipid Perox | 1995 |
Suppressive effects of tranilast on pulmonary fibrosis and activation of alveolar macrophages in mice treated with bleomycin: role of alveolar macrophages in the fibrosis.
Topics: Administration, Oral; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Free Radical Scaveng | 1995 |
Alveolar macrophage cytokine and growth factor production in a rat model of crocidolite-induced pulmonary inflammation and fibrosis.
Topics: Analysis of Variance; Animals; Asbestos, Crocidolite; Asbestosis; Bronchoalveolar Lavage Fluid; Cell | 1995 |
Antigen-induced alveolitis: cytokine production in a mouse model.
Topics: Alveolitis, Extrinsic Allergic; Animals; Antigens; Bronchoalveolar Lavage Fluid; Cytokines; Erythroc | 1995 |
Antioxidant therapy partially blocks immune-induced lung fibrosis.
Topics: Animals; Antigens, Fungal; Antioxidants; Bronchoalveolar Lavage Fluid; Collagen; Farmer's Lung; Fibr | 1995 |
Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos.
Topics: Administration, Inhalation; Animals; Asbestos, Serpentine; Bromodeoxyuridine; Bronchoalveolar Lavage | 1995 |
Correlation between high resolution computed tomography and tissue morphometry of the lung in bleomycin-induced pulmonary fibrosis in the rabbit.
Topics: Analysis of Variance; Animals; Bleomycin; Disease Models, Animal; Hydroxyproline; Lung; Male; Oxygen | 1993 |
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Interleukin-1; Lung; Mice; Mice, I | 1993 |
Pulmonary responses to amiodarone in hamsters: comparison of intratracheal and oral administrations.
Topics: Administration, Oral; Amiodarone; Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Hydroxyproline; | 1995 |
Hapten-immune pulmonary interstitial fibrosis (HIPIF) in mice requires both CD4+ and CD8+ T lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Disease Models, | 1993 |
A protective role for T lymphocytes in asbestos-induced pulmonary inflammation and collagen deposition.
Topics: Animals; Asbestos, Serpentine; Asbestosis; Base Sequence; Bronchoalveolar Lavage Fluid; Collagen; Di | 1994 |
Dose-responsive increases in pulmonary fibrosis after inhalation of asbestos.
Topics: Administration, Inhalation; Animals; Asbestos, Crocidolite; Asbestosis; Blotting, Northern; Blotting | 1994 |
Consequences of prolonged inhalation of ozone on Fischer-344/N rats: collaborative studies. Part I: Content and cross-linking of lung collagen.
Topics: Air Pollutants; Animals; Chronic Disease; Collagen; Cross-Linking Reagents; Disease Models, Animal; | 1994 |
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster.
Topics: Amiodarone; Animals; Cricetinae; Hydroxyproline; Lung; Male; Mesocricetus; Organ Size; Pulmonary Fib | 1994 |
Trichloroethylene induces pulmonary fibrosis in mice.
Topics: Animals; Elasticity; Environmental Pollutants; Hydroxyproline; Lung; Male; Mice; Mice, Inbred Strain | 1994 |
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Hydro | 1994 |
A new model of progressive pulmonary fibrosis in rats.
Topics: Administration, Inhalation; Animals; Collagen; Desmosine; Disease Models, Animal; DNA; Elastin; Envi | 1993 |
Effect of dehydroproline as a collagen synthetic inhibitor in paraquat-induced pulmonary fibrosis in beagle dogs.
Topics: Animals; Body Weight; Catalase; Collagen; Dogs; Female; Hydroxyproline; Lipid Peroxides; Male; Paraq | 1993 |
Increased susceptibility to silicosis and TNF-alpha production in C57BL/6J mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Susceptibility; Enzyme-Linked Immunosorbe | 1995 |
Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.
Topics: Animals; Bleomycin; Female; Fibrinolysis; Hydroxyproline; Lung; Male; Mice; Mice, Knockout; Mice, Tr | 1996 |
Mechanism of antifibrotic effect of taurine and niacin in the multidose bleomycin-hamster model of lung fibrosis: inhibition of lysyl oxidase and collagenase.
Topics: Animals; Bleomycin; Cricetinae; Hydroxyproline; Male; Matrix Metalloproteinase Inhibitors; Mesocrice | 1995 |
Amiodarone-induced pulmonary fibrosis in Fischer 344 rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Carbon Monoxide; Diffusion; Disease Models, Animal; Fem | 1996 |
Immunologic alterations in bleomycin-treated mice: role of pulmonary fibrosis in the modulation of immune responses.
Topics: Animals; Bleomycin; Cell Division; Cells, Cultured; Female; Hydroxyproline; Interleukin-2; Lymphocyt | 1996 |
Integrin alpha E beta 7 expression on BAL CD4+, CD8+, and gamma delta T-cells in bleomycin-induced lung fibrosis in mouse.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cadherins; CD4-Positive T-Lymphocytes; CD8-Positiv | 1996 |
Biochemical and morphological characterization of carbon tetrachloride-induced lung fibrosis in rats.
Topics: Animals; Carbon Tetrachloride; Convalescence; Dose-Response Relationship, Drug; Drug Administration | 1996 |
Contribution of T lymphocytes to the development of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Cyclosporine; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydroxyproline; | 1996 |
Heparin attenuates bleomycin but not silica-induced pulmonary fibrosis in mice: possible relationship with involvement of myofibroblasts in bleomycin, and fibroblasts in silica-induced fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cytoskeletal Proteins; Female; Fibroblasts; Hepari | 1996 |
Transgenic mice expressing the Sh ble bleomycin resistance gene are protected against bleomycin-induced pulmonary fibrosis.
Topics: Acetyltransferases; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bacterial | 1996 |
T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hydroxyproline; Inflammation; Lung; Lung Diseases; Male; Mice | 1996 |
Chronic exposure of rats to ozone and sulfuric acid aerosol: biochemical and structural responses.
Topics: Aerosols; Animals; Dose-Response Relationship, Drug; Drug Synergism; Hydroxyproline; Lung; Male; Ozo | 1997 |
Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclophosphamide; Hydroxyproline; Injections, Intr | 1997 |
Modulation of silica-induced pulmonary toxicity by dexamethasone-containing liposomes.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Dexamethasone; Drug Carriers; Drug | 1997 |
Protective effect of liposomal alpha-tocopherol against bleomycin-induced lung injury.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alkaline Phosphatase; Analysis of Variance; Animals; Antibiotics | 1997 |
Polymer of proline analogue with sustained antifibrotic activity in lung fibrosis.
Topics: Animals; Bleomycin; Collagen; Delayed-Action Preparations; Drug Carriers; Hydroxyproline; Instillati | 1997 |
Regression of chronic hypoxia-induced pulmonary hypertension, right ventricular hypertrophy, and fibrosis: effect of enalapril.
Topics: Altitude Sickness; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chronic Disease; | 1997 |
gamma-Linolenic acid-containing diet attenuates bleomycin-induced lung fibrosis in hamsters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Bleomycin; Cricetinae | 1997 |
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.
Topics: Actins; Adenoviridae; Animals; Collagen; Elastin; Fibronectins; Gene Transfer Techniques; Genetic Ve | 1997 |
Annexin I in fibrotic rat lung and cultured lung fibroblasts following irradiation.
Topics: Animals; Annexin A1; Cells, Cultured; Collagen; Fibroblasts; Hydroxyproline; Lung; Male; Organ Size; | 1997 |
Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen.
Topics: Animals; Antibodies; Apoptosis; Biotin; Bronchoalveolar Lavage Fluid; Cross-Linking Reagents; Deoxyu | 1997 |
Colchicine does not ameliorate bleomycin-induced pulmonary injury in hamsters.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Colchicine; Cricetinae; Hydroxyproline; Lung; Male | 1997 |
Pirfenidone attenuates bleomycin-induced changes in pulmonary functions in hamsters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Body Weight; Cardiovascular System; Cri | 1997 |
Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis.
Topics: Animals; Bleomycin; Cricetinae; Decorin; Extracellular Matrix Proteins; Hydroxyproline; Immunohistoc | 1997 |
Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cytokines; | 1997 |
Role of interleukin-10 in the lung response to silica in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Female; Hydroxyproline; In | 1998 |
Kinetic alterations of angiotensin-II and nitric oxide in radiation pulmonary fibrosis.
Topics: Angiotensin II; Animals; Azo Compounds; Hydroxyproline; Immunohistochemistry; In Situ Hybridization; | 1998 |
The protective action of taurine and L-arginine in radiation pulmonary fibrosis.
Topics: Animals; Arginine; Azo Compounds; Collagen; Hydroxyproline; Image Processing, Computer-Assisted; In | 1998 |
Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Granuloma; Hydroxyproline; Lu | 1998 |
Biochemical and connective tissue changes in cyclophosphamide-induced lung fibrosis in rats.
Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Collagen; Connective Tissue; Cyclophosphamide; D | 1998 |
Increase of mast cells in the liver and lung may be associated with but not a cause of fibrosis: demonstration using mast cell-deficient Ws/Ws rats.
Topics: Animals; Cell Count; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lung; Male; Mast Cells; P | 1998 |
Mineral dusts directly induce epithelial and interstitial fibrogenic mediators and matrix components in the airway wall.
Topics: Airway Obstruction; Animals; Asbestos, Amosite; Culture Techniques; Dust; Epithelium; Extracellular | 1998 |
Effects of pirfenidone on procollagen gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cricetinae; Gene Expression Regulation; | 1999 |
T cell independence of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Collagen; Female; Flow Cytometry; Hydro | 1999 |
Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Collagen; Cricetinae; Dietary Supplements; Hydroxyproli | 1999 |
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Fas Ligand Protein; fas Receptor; Humans; Hydroxyproline; Immunoglobu | 1999 |
Use of tetrandrine to differentiate between mechanisms involved in silica-versus bleomycin-induced fibrosis.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Benzylisoq | 1999 |
Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Division; Collag | 1999 |
Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Blotting, Northern; Collagen; Female; Hydroxyproline; Immunohistochemistry; Lung | 1999 |
Application of laser scanning confocal microscopy in the analysis of particle-induced pulmonary fibrosis.
Topics: Animals; Body Weight; Ferric Compounds; Hydroxyproline; Intubation, Intratracheal; Isoquinolines; Lu | 1999 |
In vivo gene transfer of an extracellular domain of platelet-derived growth factor beta receptor by the HVJ-liposome method ameliorates bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; COS Cells; Gene Transfer Techniques; Hydroxyproline; Immunohistochemistry; Lipos | 1999 |
Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Down-Reg | 2000 |
Quantitative image analysis of lung connective tissue in murine silicosis.
Topics: Animals; Collagen; Connective Tissue; Fluorescent Dyes; Hydroxyproline; Image Processing, Computer-A | 2000 |
Inhibitory effects of a lecithinized superoxide dismutase on bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Interleukin-1; Lung; Male; Methylp | 2000 |
Lack of effect of small high-dose volumes on the dose-response relationship for the development of fibrosis in distant parts of the ipsilateral lung in mini-pigs.
Topics: Animals; Dose-Response Relationship, Radiation; Female; Hydroxyproline; Lung; Male; Pulmonary Fibros | 2000 |
Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell C | 2000 |
The Fas/Fas-ligand system is not required for bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Hydroxyproline; In Sit | 2000 |
Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin.
Topics: Animals; Bleomycin; Bronchi; Bronchoalveolar Lavage Fluid; Cell Count; Desmosine; Genotype; Hydroxyp | 2000 |
Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation | 2000 |
Role of diminished epithelial GM-CSF in the pathogenesis of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Antibodies; Bleomycin; Cells, Cultured; Epithelium; Granulocyte-Macrophage Colony-Stimulati | 2000 |
Effect of interferon-gamma on experimental scleroderma induced by bleomycin.
Topics: Animals; Bleomycin; Female; Hydroxyproline; Interferon-gamma; Mice; Mice, Inbred BALB C; Pulmonary F | 2000 |
Early molecular and cellular events of oxidant-induced pulmonary fibrosis in rats.
Topics: Administration, Inhalation; Albumins; Animals; Blotting, Northern; Body Weight; Bronchoalveolar Lava | 2000 |
A characterization of amiodarone-induced pulmonary toxicity in F344 rats and identification of surfactant protein-D as a potential biomarker for the development of the toxicity.
Topics: Albumins; Amiodarone; Animals; Anti-Arrhythmia Agents; Biomarkers; Bronchoalveolar Lavage Fluid; Cel | 2000 |
Bleomycin-induced pulmonary injury in mice deficient in SPARC.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Injections, Intraperitoneal; Intubation, Intratracheal | 2000 |
Bleomycin-induced pulmonary fibrosis is independent of eosinophils.
Topics: Animals; Antibodies, Monoclonal; Bleomycin; Collagen; Eosinophil Peroxidase; Eosinophils; Gene Expre | 2000 |
Effect of antibody against integrin alpha4 on bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Anti-Bacterial Agents; Antibodies; Antigens, CD; Bleomycin; Bronchoalveolar Lavage | 2000 |
Hepatocyte growth factor attenuates collagen accumulation in a murine model of pulmonary fibrosis.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Bleomycin; Cells, Cultured; Collagen; Disease | 2000 |
A critical role for alveolar macrophages in elicitation of pulmonary immune fibrosis.
Topics: Adoptive Transfer; Animals; Autoimmune Diseases; Bronchoalveolar Lavage Fluid; Dendritic Cells; Fema | 2000 |
Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor.
Topics: Administration, Inhalation; Amino Acid Chloromethyl Ketones; Animals; Bleomycin; Blotting, Western; | 2001 |
CD40/CD40 ligand interactions are critical for elicitation of autoimmune-mediated fibrosis in the lung.
Topics: Animals; Antibodies, Blocking; Autoimmune Diseases; Bronchoalveolar Lavage Fluid; CD40 Antigens; CD4 | 2001 |
Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemotaxis; Disease Models, Animal; Female; Hydroxyproline; I | 2001 |
Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Disease Models, Animal; Hydr | 2001 |
Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin.
Topics: Adenoviridae; Animals; Antibiotics, Antineoplastic; Bleomycin; Decorin; Extracellular Matrix Protein | 2001 |
Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat.
Topics: Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Cell Count; Hydroxyproline; Male; Mat | 2001 |
Rat model of lung fibrosis: comparison of functional, biochemical, and histopathological changes 4 months after single irradiation of the right hemithorax.
Topics: Airway Resistance; Animals; Disease Models, Animal; Histocytochemistry; Hydroxyproline; Lung; Lung V | 2001 |
Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Crystallization; Disease Models, Animal; Flow Cytometry; Gene | 2001 |
Pulmonary fibrosis is increased in mice carrying the factor V Leiden mutation following bleomycin injury.
Topics: Activated Protein C Resistance; Animals; Bleomycin; Disease Models, Animal; Factor V; Hydroxyproline | 2001 |
Attenuation of bleomycin-induced pneumopathy in mice by monoclonal antibody to interleukin-12.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cyt | 2001 |
Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung.
Topics: Adenoviridae; Animals; Biglycan; Bronchoalveolar Lavage Fluid; Cell Line; Decorin; Dose-Response Rel | 2001 |
Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse.
Topics: Animals; Bleomycin; Blood Coagulation; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Anima | 2001 |
IL-12 attenuates bleomycin-induced pulmonary fibrosis.
Topics: Animals; Antibodies; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Hydroxyproline; Interferon-gam | 2001 |
Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin.
Topics: Animals; Antioxidants; Bleomycin; Collagen; Hydroxyproline; Male; Metalloporphyrins; Mice; Mice, Inb | 2001 |
Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.
Topics: Amiodarone; Animals; Gene Expression Regulation; Humans; Hydroxyproline; Immunohistochemistry; Lung; | 2001 |
Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity in rat.
Topics: Animals; Bleomycin; Guanidines; Hydroxyproline; Lung; Male; Malondialdehyde; Nitric Oxide; Pulmonary | 2001 |
IL-12p40(-/-) mice treated with intratracheal bleomycin exhibit decreased pulmonary inflammation and increased fibrosis.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokine | 2002 |
Protection from pulmonary fibrosis in leukotriene-deficient mice.
Topics: Animals; Anti-Bacterial Agents; Arachidonate 5-Lipoxygenase; Bleomycin; Bronchoalveolar Lavage Fluid | 2002 |
[In vitro studies on the bioactive materials released by lung fibroblasts in experimental pulmonary fibrosis].
Topics: Animals; Bronchoalveolar Lavage Fluid; Collagen; Fibroblasts; Hyaluronic Acid; Hydroxyproline; Inter | 1999 |
Captopril inhibits the pulmonary toxicity of paraquat in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Combinati | 2001 |
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Chemokines; Down-Regulation; Female; Humans; Hydroxyproli | 2002 |
A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cytosol; Eicosanoids; Hydroxyproline; In | 2002 |
Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice.
Topics: Animals; Collagen Type III; Dose-Response Relationship, Radiation; Hydroxyproline; Intercellular Adh | 2002 |
Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Bleomycin; Disease Models, | 2002 |
A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis.
Topics: Activating Transcription Factor 2; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar | 2002 |
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; L | 1979 |
Pulmonary fibrosis in severe acute respiratory failure.
Topics: Acute Disease; Adolescent; Adult; Collagen; Female; Humans; Hydroxyproline; Lung; Male; Middle Aged; | 1979 |
Pulmonary fibrosis--a possible mechanism.
Topics: Animals; Butylated Hydroxytoluene; DNA; Hydroxyproline; Lung; Male; Mice; Mice, Inbred BALB C; Organ | 1979 |
The effect of colchicine on the accumulation of hydroxyproline and on lung compliance after irradiation.
Topics: Animals; Colchicine; Collagen; Dose-Response Relationship, Drug; Hydroxyproline; Lung Compliance; Ma | 1978 |
Paraquat-induced changes in the rate of collagen biosynthesis by rat lung explants.
Topics: Animals; Collagen; Hydroxyproline; In Vitro Techniques; Lung; Paraquat; Proline; Pulmonary Fibrosis; | 1978 |
Experimental radiation pneumonitis: changes in physiology of the alveolar surface.
Topics: Animals; Female; Hydroxyproline; Lung; Lung Compliance; Macrophages; Mice; Phospholipids; Pleural Ef | 1978 |
[An experimental study on fibrogenesity of the oil absorbant particles made of perlite expanded (author's transl)].
Topics: Absorption; Animals; Hydroxyproline; Lung; Male; Minerals; Oils; Particle Size; Pulmonary Fibrosis; | 1978 |
[Biochemical studies on experimental pulmonary fibrosis in rabbits treated with N-methyl-N-nitrosourethane (author's transl)].
Topics: Acetylglucosaminidase; Animals; Female; Hexosaminidases; Hydroxyproline; Male; Monoamine Oxidase; Ni | 1977 |
Beta-aminopropionitrile as a radiation reaction preventive agent.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Letha | 1976 |
Biological alterations resulting from chronic wing irradation. II. Connective tissue alterations following inhalation of 144Ce fused clay aerosol in beagle dogs.
Topics: Aerosols; Cerium Radioisotopes; Collagen; Connective Tissue; Elastin; Glucosamine; Hydroxyproline; L | 1975 |
[Urinary excretion of hydroxyproline in children with respiratory diseases].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Humans; Hydroxyproline; Infant; Male; Pneu | 1975 |
Oxygen and lung fibrosis.
Topics: Animals; Body Weight; Environmental Exposure; Fatty Acids; Hydroxyproline; L-Lactate Dehydrogenase; | 1975 |
Development of a bleomycin hamster model of subchronic lung fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cricetinae; Disease Models | 1992 |
[The role of oxygen radicals in bleomycin-induced pulmonary fibrosis].
Topics: Animals; Bleomycin; Female; Free Radicals; Hydroxyproline; Lung; Male; Malondialdehyde; Oxygen; Pulm | 1992 |
[Experimental study of the effect of IH764-3, a potent component isolated from salviae milltiorrhize, against pulmonary fibrosis].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Bronchoalveolar Lavage Fluid; Drug Comb | 1992 |
[Protective effect of 764-3 on experimental lung fibrosis in rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Drug Combinations; Drugs, Chinese Herba | 1992 |
[A preliminary approach to pathological and biochemical changes of the lungs injured by domestic pingyangmycinum].
Topics: Animals; Bleomycin; Hydroxyproline; Lung; Male; Mice; Peptidyl-Dipeptidase A; Pulmonary Fibrosis; Su | 1992 |
Effects of niacin on bleomycin-induced increases in myeloperoxidase, prolyl hydroxylase, and superoxide dismutase activities and collagen accumulation in the lungs of hamsters.
Topics: Animals; Bleomycin; Body Weight; Calcium; Collagen; Cricetinae; Hydroxyproline; Lung; Male; Mesocric | 1992 |
Instillation of chemotactic factor to silica-injected lungs lowers interstitial particle content and reduces pulmonary fibrosis.
Topics: Animals; Autoradiography; Bronchoalveolar Lavage Fluid; Chemotactic Factors; DNA; Extracellular Spac | 1992 |
Experimental influenza virus infection, silicon dioxide polymorphs, and pulmonary fibrogenesis.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Female; Hydroxyproline; Influenza A virus; Leukocyt | 1992 |
[Evaluation of fibrotic effects from dusts originating from KWK "Brzeszcze" on lung tissue].
Topics: Animals; Dust; Emphysema; Hemolysis; Hydroxyproline; Injections, Intraperitoneal; Lung; Lung Disease | 1992 |
Effects of dibutyrylcyclic adenosine monophosphate on bleomycin-induced lung toxicity in hamsters.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Bucladesine; Cricetinae; Cyclic AMP; Cyclic GMP; H | 1992 |
Alveolar accumulation of fibronectin and hyaluronan precedes bleomycin-induced pulmonary fibrosis in the rat.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Fibronectins; H | 1992 |
[The prognosis of the outcome of the inflammatory process in chronic bronchitis].
Topics: Bronchitis; Bronchoalveolar Lavage Fluid; Chronic Disease; Humans; Hyaluronoglucosaminidase; Hydroxy | 1992 |
Immunological tolerance to hapten prevents subsequent induction of hapten-immune pulmonary interstitial fibrosis (HIPIF).
Topics: Age Factors; Animals; Collagen; Dermatitis, Contact; Female; Haptens; Hydroxyproline; Hypersensitivi | 1992 |
Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cadmium; Cadmium Chloride; Cell Count; Chlorides; Disease Mod | 1992 |
Pharmacokinetics, metabolic activation, and lung toxicity of cyclophosphamide in C57/B16 and ICR mice.
Topics: Animals; Biotransformation; Cyclophosphamide; Disease Susceptibility; DNA; Hydroxyproline; Injection | 1992 |
Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment.
Topics: Administration, Oral; Amiodarone; Animals; Collagen; Cricetinae; Drug Combinations; Hydroxyproline; | 1992 |
Repeated episodes of C5a-induced neutrophil influx do not result in pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Complement C5a; Cricetinae; Hydroxyproline; Leukotriene B4; L | 1991 |
[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].
Topics: Air Pollutants; Animals; Chemical Industry; Coke; Disease Models, Animal; Dust; Ferric Compounds; Hy | 1991 |
[Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue].
Topics: Air Pollutants, Occupational; Animals; Anthracosilicosis; Coal Mining; Disease Models, Animal; Dust; | 1991 |
Surface and tissue forces, surfactant protein A, and the phospholipid components of pulmonary surfactant in bleomycin-induced pulmonary fibrosis in the rat.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Elasticity; Female; Hydroxyproline; Lung; Lung Vol | 1990 |
Effect of prostaglandin E1 infusion on leukocyte traffic and fibrosis in acute lung injury induced by bleomycin in hamsters.
Topics: Acute Disease; Alprostadil; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Movem | 1991 |
Effects and levels of coenzyme Q10 in lung and liver in bleomycin-hamster model of lung fibrosis.
Topics: Animals; Bleomycin; Chromatography, High Pressure Liquid; Cricetinae; Dose-Response Relationship, Dr | 1991 |
Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin.
Topics: Administration, Oral; Animals; Bleomycin; Calcium; Cricetinae; Drug Therapy, Combination; Hydroxypro | 1991 |
Bleomycin-induced pulmonary fibrosis in genetically mast cell-deficient WBB6F1-W/Wv mice and mechanism of the suppressive effect of tranilast, an antiallergic drug inhibiting mediator release from mast cells, on fibrosis.
Topics: Analysis of Variance; Animals; Bleomycin; Cytotoxicity, Immunologic; Female; Hydroxyproline; Lung; M | 1991 |
[A study on the inhibition effect of tetrandrine on the pingyangmycinum induced pulmonary fibrosis].
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Benzylisoq | 1991 |
The effect of chemical modification of quartz surfaces on particulate-induced pulmonary inflammation and fibrosis in the mouse.
Topics: Animals; Hemolysis; Hydroxyproline; Lung; Male; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibro | 1990 |
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Asbestosis; Bronchoalveolar Lavage Fluid; Catalase; Diseas | 1990 |
Sequential virus infections, bacterial superinfections, and fibrogenesis.
Topics: Animals; Female; Hydroxyproline; Influenza A virus; Klebsiella Infections; Klebsiella pneumoniae; Lu | 1990 |
[The interrelation of collagen metabolism and fibrosis formation in patients with disseminated processes of the lungs].
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Collagen; Female; Humans; Hydroxyproline; Lung Diseases | 1990 |
Influenza virus infection, ozone exposure, and fibrogenesis.
Topics: Air Pollutants; Albumins; Animals; Bronchoalveolar Lavage Fluid; Female; Hydroxyproline; Lung; Mice; | 1990 |
Early and late effects of fractionated irradiation and the kinetics of repair in rat lung.
Topics: Animals; Central Nervous System; Digestive System; Dose-Response Relationship, Radiation; Female; Hy | 1990 |
Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; DNA; Female; Hydroxyproline; Lethal Dose 50; Lung; Lung Diseases; | 1990 |
Modification of pulmonary oxygen toxicity by bleomycin treatment.
Topics: Animals; Bleomycin; Catalase; Hydroxyproline; Lung; Lung Compliance; Lung Volume Measurements; Oxyge | 1985 |
The effect of cyclosporin A on pulmonary fibrosis induced by butylated hydroxytoluene, bleomycin and beryllium sulfate.
Topics: Animals; Beryllium; Bleomycin; Butylated Hydroxytoluene; Cyclosporins; Hydroxyproline; Male; Mice; M | 1985 |
Bleomycin-induced lung injury in the rabbit. Analysis and correlation of bronchoalveolar lavage, morphometrics, and fibroblast stimulating activity.
Topics: Animals; Bleomycin; Bronchi; Fibroblasts; Hydroxyproline; Lung; Lung Diseases; Male; Pulmonary Alveo | 1985 |
Progressive pulmonary fibrosis in rats: a biochemical, cell kinetic, and morphologic analysis.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Male; Oxygen; Pulmonary Alveoli; Pulmonary Fibrosis; R | 1985 |
Attenuation of pulmonary fibrosis in mice by aminophylline.
Topics: Aminophylline; Animals; Bleomycin; Butylated Hydroxytoluene; Collagen; Cyclic AMP; Cyclic GMP; Hydro | 1985 |
Reduction in bleomycin-induced lung hydroxyproline content by an iron chelating agent.
Topics: Animals; Bleomycin; Chelating Agents; Cricetinae; Deferoxamine; Hydroxyproline; Iron; Lung; Male; Me | 1986 |
D-penicillamine prevents collagen accumulation in lungs of rats given bleomycin.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Lung; Penicillamine; Pulmonary Fibrosis; Rats; Rats, I | 1986 |
Effect of intratracheally administered anticancer drugs on lung hydroxyproline content.
Topics: Animals; Antineoplastic Agents; Bleomycin; Hydroxyproline; Intubation, Intratracheal; Lung; Male; Mi | 1986 |
Intratracheal versus intravenous administration of bleomycin in mice: acute effects.
Topics: Animals; Bleomycin; Cell Division; Hydroxyproline; Hyperplasia; Injections, Intravenous; Intubation, | 1986 |
Ameliorating effect of murine interferon gamma on bleomycin-induced lung collagen fibrosis in mice.
Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Interferon-gamma; Male; Mice; Pulmonary Fibrosis | 1986 |
Biosynthesis of interstitial and basement membrane collagens in pulmonary fibrosis.
Topics: Animals; Basement Membrane; Bleomycin; Collagen; Extracellular Matrix; Hydroxyproline; Lung; Male; M | 1986 |
Bleomycin for the cure of Trypanosoma brucei brucei infections in mice: lack of pulmonary toxicity.
Topics: Animals; Bleomycin; Hydroxyproline; Lung; Mice; Pulmonary Fibrosis; Trypanosoma brucei brucei; Trypa | 1986 |
Modulation of the effects of alveolar macrophages on lung fibroblast collagen production rate.
Topics: Animals; Bleomycin; Cells, Cultured; Collagen; Cricetinae; Dinoprostone; Fibroblasts; Humans; Hydrox | 1987 |
Effects of dietary fats on bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Coconut Oil; Dietary Fats; Fats; Hydroxyproline; Leukocyte Count; Lipid Peroxide | 1987 |
[Protective effect of dan-shen on bleomycin A5-induced lung fibrosis in mice].
Topics: Animals; Bleomycin; Drug Combinations; Drugs, Chinese Herbal; Hydroxyproline; Lung; Male; Mice; Orga | 1987 |
High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Female; Hydroxyproline; Lung; Mice; Mice, Inbred BALB C; | 1987 |
Absence of an additional fibrotic response caused by oxygen in the lungs of rats after the intratracheal administration of bleomycin.
Topics: Animals; Bleomycin; Female; Hydroxyproline; Lung; Oxygen; Pulmonary Fibrosis; Rats; Rats, Inbred Str | 1988 |
Relation between acute-phase proteins and enhanced bleomycin-induced pulmonary fibrosis in the rat.
Topics: Acute-Phase Proteins; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Bleomycin; DNA; Hexosamine | 1988 |
Non-lethal hyperoxic potentiation of lung disease in the rat following subcutaneous administration of bleomycin.
Topics: Animals; Bleomycin; Drug Synergism; Hydroxyproline; Injections, Subcutaneous; Male; Organ Size; Oxyg | 1988 |
Ameliorating effect of an interferon inducer polyinosinic-polycytidylic acid on bleomycin-induced lung fibrosis in hamsters. Morphologic and biochemical evidence.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Disease Models, Animal; Hydr | 1988 |
Effects of dimethyl sulfoxide (DMSO) on pulmonary fibrosis in rats and mice.
Topics: Animals; Bleomycin; Butylated Hydroxytoluene; Dimethyl Sulfoxide; Female; Free Radicals; Hydroxyprol | 1989 |
Dietary fish oil inhibits bleomycin-induced pulmonary fibrosis in the rat.
Topics: Animals; Bleomycin; Dietary Fats, Unsaturated; DNA; Fish Oils; Hydroxyproline; Lung; Male; Malondial | 1989 |
Enhanced macrophage-fibroblast interactions in the pulmonary interstitium increases fibrosis after silica injection to monocyte-depleted mice.
Topics: Animals; Autoradiography; Bronchoalveolar Lavage Fluid; Cell Communication; Fibroblasts; Hydroxyprol | 1989 |
Radiation-induced pulmonary endothelial dysfunction and hydroxyproline accumulation in four strains of mice.
Topics: Animals; Endothelium; Hydroxyproline; Lung; Male; Mice; Mice, Inbred Strains; Peptidyl-Dipeptidase A | 1989 |
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Histo | 1989 |
The effect of crystal structure on mouse lung inflammation and fibrosis.
Topics: Animals; Crystallization; Hemolysis; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Models, Molecul | 1988 |
The combination of ozone and silica on the development of pulmonary fibrosis.
Topics: Animals; DNA; Drug Interactions; Hydroxyproline; Lung; Male; Ozone; Protein-Lysine 6-Oxidase; Protei | 1986 |
Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine.
Topics: Animals; Body Weight; Captopril; Hydroxyproline; Lung; Male; Monocrotaline; Organ Size; Penicillamin | 1985 |
Bronchiolar and alveolar lesions in the pathogenesis of crocidolite-induced pulmonary fibrosis in mice.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Bronchi; Connective Tissue; Epithelium; Hydroxyproline; Lu | 1985 |
Crocidolite-induced pulmonary fibrosis in mice. Cytokinetic and biochemical studies.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Autoradiography; Bronchi; Cell Division; Collagen; DNA; Ep | 1986 |
A light microscopic and biochemical study of carbon tetrachloride-induced pulmonary fibrosis in rats: the preventive effect of malotilate.
Topics: Animals; Carbon Tetrachloride; Collagen; Female; Fibroblasts; Hydroxyproline; Malonates; Pulmonary F | 1987 |
[Relation between body weight, lung mass and hydroxyproline level in animals exposed to soil dusts and coal ash].
Topics: Air Pollutants; Animals; Body Weight; Carbon; Coal; Coal Ash; Hydroxyproline; Lung; Male; Particulat | 1987 |
Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis.
Topics: Animals; Autoradiography; Cell Division; Collagen; DNA; Epithelium; Hydroxyproline; Male; Mice; Orga | 1988 |
Effects of chronic exposure to ozone on collagen in rat lung.
Topics: Animals; Body Weight; Collagen; Dose-Response Relationship, Drug; Hydroxyproline; Lung; Male; Organ | 1988 |
Pulmonary interstitial fibrosis induced in hapten-immune hamsters.
Topics: Animals; Collagen; Cricetinae; Dermatitis, Contact; Disease Models, Animal; Haptens; Histocytochemis | 1987 |
Pulmonary hydroxyproline content and production following treatment of mice with O,S,S-trimethyl phosphorodithioate.
Topics: Animals; Carmustine; Hydroxyproline; Lung; Male; Mice; Mice, Inbred BALB C; Organothiophosphates; Or | 1987 |
Unilateral paraquat-induced lung fibrosis: evolution of changes in lung fibronectin and collagen after graded degrees of lung injury.
Topics: Albumins; Animals; Collagen; Enzyme-Linked Immunosorbent Assay; Fibronectins; Hydroxyproline; Lung; | 1987 |
The corrected collagen content in paraquat lungs.
Topics: Adult; Aged; Collagen; Female; Humans; Hydroxyproline; Lung; Male; Middle Aged; Paraquat; Pulmonary | 1986 |
[Behavior of urinary hydroxyproline and the effect of cigarette smoking in silicosis].
Topics: Adult; Aging; Female; Humans; Hydroxyproline; Male; Middle Aged; Pulmonary Fibrosis; Radiography; Si | 1986 |
Pathophysiologic correlations in asbestos-induced airway disease in the guinea pig.
Topics: Animals; Asbestos; Asbestosis; Bronchi; Female; Guinea Pigs; Hydroxyproline; Lung; Lung Diseases, Ob | 1986 |
Protection by methylprednisolone against butylated hydroxytoluene-induced pulmonary damage and impairment of microsomal monooxygenase activities in the mouse: lack of effect on fibrosis.
Topics: Animals; Butylated Hydroxytoluene; Hydroxyproline; Lung; Male; Methylprednisolone; Mice; Mice, Inbre | 1986 |
Changes in lung tissue and lavage fibronectin after paraquat injury in rats.
Topics: Albumins; Animals; Fibronectins; Hydroxyproline; Lung; Lung Injury; Paraquat; Pulmonary Fibrosis; Ra | 1986 |
Histopathologic features of phorbol myristate acetate-induced lung injury.
Topics: Acute Disease; Animals; Bronchi; Dose-Response Relationship, Drug; Drug Administration Schedule; Fem | 1985 |
The development and interlobar distribution of plutonium-induced pulmonary fibrosis in mice.
Topics: Animals; Autoradiography; DNA; Female; Hydroxyproline; Lung; Male; Organ Size; Plutonium; Proteins; | 1985 |
Vascular permeability and late radiation fibrosis in mouse lung.
Topics: Albumins; Animals; Blood Proteins; Blood Volume; Capillary Permeability; Collagen; Female; Fibrin; F | 1985 |
[Dose-time studies of radiogenic pneumopathy. IV. Hydroxyproline content of lung tissue of 60Co-gamma-irradiated young pigs].
Topics: Animals; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Gamma Rays; Hydroxyproline; Lu | 1985 |
[Morphological and biochemical studies on the behavior of connective tissue in pulmonary fibrosis due to irradiation].
Topics: Animals; Cobalt Isotopes; Collagen; Connective Tissue; Glycosaminoglycans; Histocytochemistry; Hydro | 1973 |
Lactate dehydrogenase isoenzymes during the development of experimental fibrosis.
Topics: Animals; Buffers; Centrifugation; Collagen; Cystic Fibrosis; Electrophoresis; Hydroxyproline; Isoenz | 1970 |
Collagen biosynthesis in rat lungs during exposure to asbestos.
Topics: Animals; Asbestos; Asbestosis; Carbon Isotopes; Cell-Free System; Collagen; Hydroxylation; Hydroxypr | 1971 |
Protocollagen proline hydroxylase activity in experimental pulmonary fibrosis of rats.
Topics: Animals; Ascorbic Acid; Collagen; Disease Models, Animal; Hydroxyproline; Iron; Ketoglutaric Acids; | 1970 |
Lung connective tissue measurements. I. Amino acid analysis procedures for determination of canine lung connective tissue.
Topics: Animals; Aspartic Acid; Autoanalysis; Chromatography, Ion Exchange; Collagen; Connective Tissue; Dog | 1971 |