hydroxyproline has been researched along with Acromegaly in 48 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight selected patients with active acromegaly and elevated GH levels without other endocrine disturbances were submitted to long-term treatment and acute dose-response trials with bromocriptine." | 9.04 | Bromocriptine treatment in acromegaly: clinical and biochemical effects. ( Bohmer, T; Halse, J; Haugen, HN, 1977) |
| "Eleven patients with active acromegaly were treated with bromocriptine for one year or more." | 9.04 | Bromocriptine therapy in eleven patients with acromegaly. ( Boström, H; Ljunghall, S; Lundin, L; Wide, L, 1978) |
| "A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0." | 7.66 | Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978) |
| "Urinary excretion of hydroxyproline was examined with the Hypronosticon test in 25 patients with acromegaly (13 men, 12 women) and 15 healthy persons." | 7.65 | [Urinary excretion of hydroxyproline in acromegaly (author's transl)]. ( Irmscher, K; Krüskemper, HL; Lepszy, H; Solbach, HG; Wiegelmann, W, 1976) |
| "Eight selected patients with active acromegaly and elevated GH levels without other endocrine disturbances were submitted to long-term treatment and acute dose-response trials with bromocriptine." | 5.04 | Bromocriptine treatment in acromegaly: clinical and biochemical effects. ( Bohmer, T; Halse, J; Haugen, HN, 1977) |
| "Eleven patients with active acromegaly were treated with bromocriptine for one year or more." | 5.04 | Bromocriptine therapy in eleven patients with acromegaly. ( Boström, H; Ljunghall, S; Lundin, L; Wide, L, 1978) |
| " In eight patients with active acromegaly, urinary free pyridinoline and deoxypyridinoline, and serum osteocalcin, propeptide of type 1 procollagen, vitamin D, 1000 h parathyroid hormone, bone specific alkaline phosphatase, calcium and phosphate concentrations were measured before and after 6 months treatment with octreotide." | 3.70 | Gonadal status is an important determinant of bone density in acromegaly. ( Farquharson, R; Fraser, WD; Hipkin, L; Lesse, GP; Vora, JP, 1998) |
| "A significant correlation between the activity of the bone isoenzyme or serum alkaline phosphatase and the urinary hydroxyproline excretion in osteomalacia, osteoporosis, primary hyperparathyroidism with osteodystrophy, Paget's disease, secondary bone tumours, and in a control group was found (P less than 0." | 3.66 | Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases. ( Formánková, J; Horn, V; Hrba, J; Konopásek, B; Marek, J; Pacovský, V; Silinková-Málková, E; Stĕpán, J; Vokrouhlická, O, 1978) |
| "Urinary excretion of hydroxyproline was examined with the Hypronosticon test in 25 patients with acromegaly (13 men, 12 women) and 15 healthy persons." | 3.65 | [Urinary excretion of hydroxyproline in acromegaly (author's transl)]. ( Irmscher, K; Krüskemper, HL; Lepszy, H; Solbach, HG; Wiegelmann, W, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (89.58) | 18.7374 |
| 1990's | 3 (6.25) | 18.2507 |
| 2000's | 2 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BENOIT, FL | 2 |
| THEIL, GB | 1 |
| WATTEN, RH | 2 |
| JOHNSTON, CC | 1 |
| DEISS, WP | 1 |
| Cappelli, C | 1 |
| Gandossi, E | 1 |
| Agosti, B | 1 |
| Cerudelli, B | 1 |
| Cumetti, D | 1 |
| Castellano, M | 1 |
| Pirola, I | 1 |
| De Martino, E | 1 |
| Rosei, EA | 1 |
| Biermasz, NR | 1 |
| Hamdy, NA | 1 |
| Pereira, AM | 1 |
| Romijn, JA | 1 |
| Roelfsema, F | 1 |
| Borel, JP | 1 |
| Caranjot, JM | 1 |
| Jayle, MF | 1 |
| Bijlsma, JW | 1 |
| Nortier, JW | 1 |
| Duursma, SA | 1 |
| Croughs, RJ | 1 |
| Bosch, R | 1 |
| Thijssen, JH | 1 |
| Marek, J | 4 |
| Srámková, J | 1 |
| Schüllerová, M | 1 |
| Stĕpán, J | 4 |
| Schreiberová, O | 1 |
| Halse, J | 4 |
| Gordeladze, JO | 3 |
| Clemmons, DR | 1 |
| Underwood, LE | 1 |
| Ridgway, EC | 1 |
| Kliman, B | 1 |
| Kjellberg, RN | 1 |
| Van Wyk, JJ | 1 |
| Marazuela, M | 1 |
| Astigarraga, B | 1 |
| Tabuenca, MJ | 1 |
| Estrada, J | 1 |
| Marín, F | 1 |
| Lucas, T | 1 |
| Kotzmann, H | 1 |
| Bernecker, P | 1 |
| Hübsch, P | 1 |
| Pietschmann, P | 1 |
| Woloszczuk, W | 1 |
| Svoboda, T | 1 |
| Geyer, G | 1 |
| Luger, A | 1 |
| Lesse, GP | 1 |
| Fraser, WD | 1 |
| Farquharson, R | 1 |
| Hipkin, L | 1 |
| Vora, JP | 1 |
| Havránek, T | 2 |
| Dolezal, V | 2 |
| Pacovský, V | 2 |
| Horn, V | 1 |
| Silinková-Málková, E | 1 |
| Vokrouhlická, O | 1 |
| Konopásek, B | 1 |
| Formánková, J | 2 |
| Hrba, J | 1 |
| Haugen, HN | 2 |
| Bohmer, T | 2 |
| Lundin, L | 1 |
| Ljunghall, S | 1 |
| Wide, L | 1 |
| Boström, H | 1 |
| Belforte, L | 1 |
| Camanni, F | 1 |
| Chiodini, PG | 1 |
| Liuzzi, A | 1 |
| Massara, F | 1 |
| Molinatti, GM | 1 |
| Müller, EE | 1 |
| Silvestrini, F | 1 |
| Rodnan, GP | 1 |
| Lipinski, E | 1 |
| Luksick, J | 1 |
| Djøoseland, O | 1 |
| Leicht, E | 1 |
| Langer, HJ | 1 |
| Stelzer, K | 1 |
| Blum, C | 1 |
| Thorner, MO | 2 |
| Besser, GM | 2 |
| Chait, A | 1 |
| Aitken, M | 1 |
| Benker, G | 1 |
| Bloom, SR | 1 |
| Mortimer, CH | 1 |
| Sanders, P | 1 |
| Mason, AS | 1 |
| Touliatos, J | 1 |
| Lindholm, BW | 1 |
| Lepszy, H | 1 |
| Irmscher, K | 1 |
| Wiegelmann, W | 1 |
| Solbach, HG | 1 |
| Krüskemper, HL | 1 |
| Oberländer, J | 1 |
| Bottermann, P | 1 |
| Kozak, GP | 1 |
| Vagnucci, AI | 1 |
| Lauler, DP | 1 |
| Thorn, GW | 1 |
| Rake, JS | 1 |
| Hafiz, SA | 1 |
| Lessof, MH | 1 |
| Snodgrass, GJ | 1 |
| Dinulescu, E | 1 |
| Ganea, E | 2 |
| Olteanu, M | 1 |
| Vontobel, F | 1 |
| Nikkilä, EA | 1 |
| Pelkonen, R | 1 |
| Taskinen, MR | 1 |
| Aro, A | 1 |
| Ege, P | 1 |
| Laron, Z | 1 |
| Pertzelan, A | 1 |
| Karp, M | 1 |
| Kowadlo-Silbergeld, A | 1 |
| Daughaday, WH | 2 |
| Haddad, JG | 1 |
| Couranz, S | 1 |
| Avioli, LV | 1 |
| Wiedemann, E | 1 |
| Schwartz, E | 2 |
| Kocher, P | 1 |
| Kivirikko, KI | 1 |
| Cerda, JJ | 1 |
| Toskes, PP | 1 |
| Shopa, NA | 1 |
| Wilkinson, JH | 1 |
| Recchia, O | 1 |
| Sereno, L | 1 |
| Isidori, A | 1 |
| Katz, FH | 1 |
| Kappas, A | 1 |
| Zatońska, I | 1 |
| Widomska-Czekajska, T | 1 |
| Echemendia, E | 1 |
| Schiffer, M | 1 |
| Panariello, VA | 1 |
| Bell, NH | 1 |
| Colwell, JA | 1 |
| Saval, F | 1 |
| Del Greco, F | 1 |
| Casey, DE | 1 |
3 reviews available for hydroxyproline and Acromegaly
| Article | Year |
|---|---|
[Urine hydroxyproline a review].
Topics: Acromegaly; Bone Resorption; Carbon Isotopes; Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hyp | 1968 |
The biosynthesis of collagen.
Topics: Acromegaly; Ascorbic Acid Deficiency; Carbon Isotopes; Collagen; Ehlers-Danlos Syndrome; Hydroxylati | 1971 |
Regulation of skeletal growth by sulfation factor.
Topics: Acromegaly; Bone and Bones; Bone Development; Cartilage; Chondroitin; DNA; Dwarfism, Pituitary; Grow | 1971 |
3 trials available for hydroxyproline and Acromegaly
| Article | Year |
|---|---|
Bromocriptine treatment in acromegaly: clinical and biochemical effects.
Topics: Acromegaly; Adult; Bromocriptine; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response R | 1977 |
Bromocriptine therapy in eleven patients with acromegaly.
Topics: Acromegaly; Adult; Aged; Bromocriptine; Clinical Trials as Topic; Drug Evaluation; Female; Glucose T | 1978 |
Administration of growth hormone to patients with familial dwarfism with high plasma immunoreactive growth hormone: measurement of sulfation factor, metabolic and linear growth responses.
Topics: Acromegaly; Adolescent; Adult; Blood; Blood Glucose; Body Weight; Calcium; Child; Child, Preschool; | 1971 |
42 other studies available for hydroxyproline and Acromegaly
| Article | Year |
|---|---|
HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.
Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Anabolic Agents; Cushing Syndrome; | 1963 |
PARATHYROID HORMONE AND URINARY HYDROXYPROLINE.
Topics: Acromegaly; Adenoma; Adolescent; Blood; Calcium; Calcium, Dietary; Geriatrics; Humans; Hydroxyprolin | 1965 |
Long-term treatment of acromegaly with lanreotide: evidence of increased serum parathormone concentration.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Calcifediol; Calcitriol; Calcium; Female; Humans; Hyd | 2004 |
Long-term maintenance of the anabolic effects of GH on the skeleton in successfully treated patients with acromegaly.
Topics: Absorptiometry, Photon; Acromegaly; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and B | 2005 |
[A method of fractionating urinary peptides containing hydroxyproline].
Topics: Acromegaly; Arthritis, Rheumatoid; Bone Neoplasms; Chemistry, Clinical; Chromatography, Ion Exchange | 1967 |
Changes in bone metabolism during treatment of acromegaly.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Acid Phosphatase; Acromegaly; Adult; Aged; Bone and Bones; | 1983 |
Long-term treatment of acromegaly with lisuride: differences of effect on growth hormone and somatomedin.
Topics: Acromegaly; Adult; Alkaline Phosphatase; Blood Glucose; Bone and Bones; Bromocriptine; Ergolines; Fe | 1981 |
Total and non-dialyzable urinary hydroxyproline in acromegalics and control subjects.
Topics: Acromegaly; Age Factors; Aged; Bone and Bones; Calcium; Collagen; Female; Growth Hormone; Humans; Hy | 1981 |
Estradiol treatment of acromegaly. Reduction of immunoreactive somatomedin-C and improvement in metabolic status.
Topics: Acromegaly; Adult; Aged; Estradiol; Female; Growth Hormone; Humans; Hydroxyproline; Male; Middle Age | 1980 |
Serum bone Gla protein as a marker of bone turnover in acromegaly.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Female; Humans; Hydroxypr | 1993 |
Bone mineral density and parameters of bone metabolism in patients with acromegaly.
Topics: Absorptiometry, Photon; Acromegaly; Adult; Aged; Bone Density; Female; Femur Neck; Growth Hormone; H | 1993 |
Gonadal status is an important determinant of bone density in acromegaly.
Topics: Acromegaly; Amino Acids; Biomarkers; Bone Density; Bone Remodeling; Case-Control Studies; Female; Fe | 1998 |
Bone isoenzyme of serum alkaline phosphatase in acromegaly.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Calcium; Female; gamma-Glutamyltransf | 1979 |
Relationship of the activity of the bone isoenzyme of serum alkaline phosphatase to urinary hydroxyproline excretion in metabolic and neoplastic bone diseases.
Topics: Acromegaly; Adult; Alkaline Phosphatase; Bone Diseases; Bone Neoplasms; Female; Humans; Hydroxyproli | 1978 |
Long-term treatment with 2-Br-alpha-ergocryptine in acromegaly.
Topics: Acromegaly; Adult; Blood Glucose; Bromocriptine; Calcium; Drug Evaluation; Ergolines; Female; Glycos | 1977 |
Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma.
Topics: Acromegaly; Adolescent; Adult; Aged; Biopsy; Collagen; Female; Humans; Hydroxyproline; Male; Middle | 1979 |
[Diagnostic effectiveness of tests on the biochemical activity in acromegaly as evaluated by discrimination analysis].
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Female; Growth Hormone; Humans; Hydroxyproline; Male; | 1978 |
Urinary hydroxyproline excretion in acromegaly.
Topics: Acromegaly; Adult; Circadian Rhythm; Collagen; Creatinine; Fasting; Female; Growth Hormone; Humans; | 1978 |
A simple procedure for the determination of hydroxyproline in urine and bone.
Topics: Acromegaly; Adult; Animals; Bone and Bones; Colorimetry; Female; Femur; Humans; Hydroxyproline; Hypo | 1978 |
[Plasma hydroxyproline determination in patients with metabolic diseases of the bone collagen].
Topics: Acromegaly; Adult; Chronic Kidney Disease-Mineral and Bone Disorder; Humans; Hydroxyproline; Hyperpa | 1978 |
Successful treatment of acromegaly with bromocriptine.
Topics: Acromegaly; Bromocriptine; Ergolines; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hydrox | 1976 |
Bromocriptine treatment of acromegaly.
Topics: Acromegaly; Adult; Aged; Blood Glucose; Bromine; Circadian Rhythm; Ergot Alkaloids; Female; Glucagon | 1975 |
Treatment of acromegaly by transsphenoidal hypophysectomy with cryoapplication.
Topics: Acromegaly; Adrenal Insufficiency; Adult; Calcium; Cerebrospinal Fluid Rhinorrhea; Cryosurgery; Diab | 1975 |
[Urinary excretion of hydroxyproline in acromegaly (author's transl)].
Topics: Acromegaly; Adult; Aged; Calcium; Female; Humans; Hydroxyproline; Male; Middle Aged; Phosphates | 1976 |
[Proceedings: Significance of hydroxyproline determination in 24-hour urine].
Topics: Acromegaly; Age Factors; Collagen; Humans; Hydroxyproline; Hyperparathyroidism; Hyperthyroidism; Met | 1974 |
Acromegaly pre- and postpituitary irradiation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adrenocorticotropic Hormone; Adult; Biopsy; | 1966 |
A trial of medroxyprogesterone acetate in acromegaly.
Topics: Acromegaly; Fasting; Glucose Tolerance Test; Growth Hormone; Humans; Hydroxyproline; Male; Medroxypr | 1972 |
[Automated determination of free and combined hydroxyproline].
Topics: Acromegaly; Autoanalysis; Colorimetry; Humans; Hydroxyproline; Marfan Syndrome | 1972 |
[Collagen in endocrine diseases with bone involvement].
Topics: Acromegaly; Bone and Bones; Bone Diseases; Collagen; Collagen Diseases; Dwarfism, Pituitary; Endocri | 1973 |
Idiopathic gingival hyperplasia and hypertrichosis associated with acromegaloid features.
Topics: Abnormalities, Multiple; Acromegaly; Adolescent; Cephalometry; Child; Child, Preschool; Connective T | 1973 |
Insulin deficiency associated with hypoglycemia and good glucose tolerance in hypopituitarism. Report of a case with acromegaly developing pituitary apoplexy.
Topics: Acromegaly; Aged; Blood Glucose; Cerebrovascular Disorders; Female; Glucose Tolerance Test; Growth H | 1974 |
Nondialyzable urinary hydroxyproline as an index of bone collagen formation.
Topics: Acromegaly; Adolescent; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Bone Resorption; Calciton | 1970 |
Suppression of growth hormone-dependent human serum sulfation factor by estrogen.
Topics: Acromegaly; Animals; Blood Proteins; Calcium; Cartilage; Depression, Chemical; Drug Antagonism; Estr | 1972 |
[Study of urinary hydroxyproline in osteopathies].
Topics: Acromegaly; Adult; Aged; Bone Neoplasms; Female; Humans; Hydroxyproline; Hyperparathyroidism; Hypert | 1966 |
[Urinary hydroxyproline and the metabolism of collagen].
Topics: Acromegaly; Bone Diseases; Child; Collagen; Collagen Diseases; Dwarfism, Pituitary; Humans; Hydroxyp | 1969 |
The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.
Topics: Acromegaly; Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Bone Diseases; Cholest | 1970 |
[Urinary hydroxyproline and circulating HGH. (Preliminary findings in some endocrine diseases)].
Topics: Acromegaly; Adolescent; Adult; Aged; Child; Diabetes Mellitus; Female; Gonadotropins; Growth Hormone | 1967 |
Influence of estradiol and estriol on urinary excretion of hydroxyproline in man.
Topics: Acromegaly; Adult; Aged; Breast Neoplasms; Creatinine; Estradiol; Estriol; Estrogens; Female; Growth | 1968 |
Renal tubular transport of hydroxyproline peptides: evidence for reabsorption and secretion.
Topics: Absorption; Acromegaly; Adult; Chromatography; Diet; Gelatin; Glomerular Filtration Rate; Humans; Hy | 1968 |
[Hydroxyproline in various diseases of the endocrine system].
Topics: Acromegaly; Adult; Aged; Female; Humans; Hydroxyproline; Hypoparathyroidism; Male; Middle Aged; Thyr | 1968 |
Mechanism of estrogenic action in acromegaly.
Topics: Acromegaly; Adult; Blood Glucose; Calcium; Calcium Isotopes; Calcium, Dietary; Diet; Ethinyl Estradi | 1969 |
Effects of calcium infusion on urinary hydroxyproline and phosphorus: evaluation as a diagnostic test.
Topics: Acromegaly; Adolescent; Adult; Aged; Calcium; Child; Female; Humans; Hydroxyproline; Hypercalcemia; | 1966 |