hydroxylysine and Uremia

hydroxylysine has been researched along with Uremia* in 3 studies

Reviews

1 review(s) available for hydroxylysine and Uremia

Article	Year
Effect of progressive end-stage renal insufficiency on bone mineral-collagen maturation. Kidney international. Supplement, 1975, Issue:2 Topics: Aldehydes; Animals; Bone and Bones; Bone Development; Bone Matrix; Calcium; Chronic Kidney Disease-Mineral and Bone Disorder; Collagen; Dipeptides; Histidine; Hydroxylysine; Kidney Failure, Chronic; Minerals; Norleucine; Uremia; Vitamin D	1975

Other Studies

2 other study(ies) available for hydroxylysine and Uremia

Article	Year
Estimation of hydroxylysine in urine and serum of patients with chronic uremia. Clinica chimica acta; international journal of clinical chemistry, 1977, Apr-01, Volume: 76, Issue:1 Free hydroxylysine and hydroxylysing glycosides were separated from urine and serum extracts on cation exchange resin and assayed spectrophotometrically. The method in conjunction with gel filtration in Bio-Gel P2 allowed to separate from urine also polypeptide hydroxylysine and hydroxylysine bound in small molecules of neutral or acidic character. Glycosylgalactosylhydroxylysineand galactosylhydroxylysine were separated by partition and/or ion exchange chromatography. Patients with chronic renal insufficiency had elevated serum levels and urinary excretion of hydroxylysine glycosides with increased excretion of hydroxylysine bound in polypeptides and in small molecules of neutral or acidic character. The excretion of free hydroxylysine was often within normal limits. When compared to values found in normal growing subjects and in adult patients with increased bone turnover and normal renin function the urinary excretion of hydroxylysine glycosides in chronic uremia was more markedly increased than excretion of hydroxyproline polypeptides and total hydroxyproline. Topics: Bone Diseases; Chemical Fractionation; Chronic Disease; Collagen; Glycosides; Humans; Hydroxylysine; Uremia	1977
The nature of the collagen cross-links in bone in the chronic uraemic state. The Biochemical journal, 1975, Volume: 145, Issue:1 The cross-links from NaB3H4-reduced bone collagen of chronically uraemic rats and pairfed controls were compared. The ratio of the reduced cross-links deltadelta'-dihydroxylysinonorleucine to delta-hydroxylysinonorleucine was significantly increased in the uraemic animals. The observed increment in the dihydroxylysinonorleucine:hydroxylysinonorleucine ratio was accentuated as the uraemic state advanced. The data indicate that osteodystrophy of chronic renal insufficiency is characterized by an alteration of the quantitative relations between cross-links and aldehydic precursors of bone collagen. Topics: Animals; Bone and Bones; Borohydrides; Chemical Phenomena; Chemistry; Collagen; Dipeptides; Female; Hydroxylysine; Nephrectomy; Norleucine; Rats; Uremia	1975

Article

Year

Estimation of hydroxylysine in urine and serum of patients with chronic uremia.

Clinica chimica acta; international journal of clinical chemistry, 1977, Apr-01, Volume: 76, Issue:1

Free hydroxylysine and hydroxylysing glycosides were separated from urine and serum extracts on cation exchange resin and assayed spectrophotometrically. The method in conjunction with gel filtration in Bio-Gel P2 allowed to separate from urine also polypeptide hydroxylysine and hydroxylysine bound in small molecules of neutral or acidic character. Glycosylgalactosylhydroxylysineand galactosylhydroxylysine were separated by partition and/or ion exchange chromatography. Patients with chronic renal insufficiency had elevated serum levels and urinary excretion of hydroxylysine glycosides with increased excretion of hydroxylysine bound in polypeptides and in small molecules of neutral or acidic character. The excretion of free hydroxylysine was often within normal limits. When compared to values found in normal growing subjects and in adult patients with increased bone turnover and normal renin function the urinary excretion of hydroxylysine glycosides in chronic uremia was more markedly increased than excretion of hydroxyproline polypeptides and total hydroxyproline.

Topics: Bone Diseases; Chemical Fractionation; Chronic Disease; Collagen; Glycosides; Humans; Hydroxylysine; Uremia

1977

The nature of the collagen cross-links in bone in the chronic uraemic state.

The Biochemical journal, 1975, Volume: 145, Issue:1

The cross-links from NaB3H4-reduced bone collagen of chronically uraemic rats and pairfed controls were compared. The ratio of the reduced cross-links deltadelta'-dihydroxylysinonorleucine to delta-hydroxylysinonorleucine was significantly increased in the uraemic animals. The observed increment in the dihydroxylysinonorleucine:hydroxylysinonorleucine ratio was accentuated as the uraemic state advanced. The data indicate that osteodystrophy of chronic renal insufficiency is characterized by an alteration of the quantitative relations between cross-links and aldehydic precursors of bone collagen.

Topics: Animals; Bone and Bones; Borohydrides; Chemical Phenomena; Chemistry; Collagen; Dipeptides; Female; Hydroxylysine; Nephrectomy; Norleucine; Rats; Uremia

1975