hydroxylysine and Neoplasm-Metastasis

hydroxylysine has been researched along with Neoplasm-Metastasis* in 2 studies

Other Studies

2 other study(ies) available for hydroxylysine and Neoplasm-Metastasis

ArticleYear
High predictivity of galactosyl-hydroxylysine in urine as an indicator of bone metastases from breast cancer.
    Clinical chemistry, 1990, Volume: 36, Issue:5

    We measured the urinary excretion of galactosyl-hydroxylysine (GH) and hydroxyproline in two groups of women with breast cancer, with (M+, n = 24) and without (Mo, n = 30) clinical, scintigraphic, or radiological evidence of bone metastases. Both these compounds are excreted in larger amounts in the M+ group than in the Mo patients. However, GH, which is a specific marker for bone collagen, provides better predictivity for bone metastases than does hydroxyproline: 92% sensitivity and 90% specificity vs 74% and 79%, respectively, for hydroxyproline.

    Topics: Adult; Bone Neoplasms; Breast Neoplasms; Diagnostic Errors; Female; Humans; Hydroxylysine; Monitoring, Physiologic; Neoplasm Metastasis; Risk

1990
Urinary excretion of hydroxyproline, hydroxylysine and hydroxylysine glycosides by patients with Paget's disease of bone and carcinoma with metastases in bone.
    Clinica chimica acta; international journal of clinical chemistry, 1979, Mar-15, Volume: 92, Issue:3

    Patient's with carcinoma metastases in bone and Pagent's disease of bone have different patterns of collagen metabolite excretion. Both forms of bone disease resulted in an increased excretion of total hydroxyproline and the ratio of glucosylgalactosylhydroxylsine to galactosylhydroxylysine was below normal. The excretion of glucosylgalactosylhydroxylysine and galactosylhydroxylysine was increased in all patients with carcinoma metastases in bone while the excretion of glucosylgalactosylhydroxylysine in patients with Paget's disease. The ratio of total hydroxylysine (free hydroxylysine + glycosylated hydroxylysines) to total hydroxyproline was normal in patients with carcinoma metastases in bone and below normal in patients with Paget's disease bosne. The pattern of urinary collagen metabolite excretion is a more specific indicator of the presence of bone disease than is the measurement of the excretion rate of any individual collagen metabolite. Bone diseases of different etiologies may result in different patterns of urinary collagen metabolite excretion.

    Topics: Bone Neoplasms; Collagen; Glycosides; Humans; Hydroxylysine; Hydroxyproline; Neoplasm Metastasis; Osteitis Deformans

1979