hydroxylamine has been researched along with Retinoblastoma in 1 studies
amino alcohol : An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using the hydroxylamine-osmium tetroxide (HOT) technique, we have identified a constitutional point mutation in the retinoblastoma susceptibility gene (RB1) which segregates with the expression of retinoblastoma in five affected family members." | 3.68 | A familial RB1 mutation detected by the HOT technique is homozygous in a second primary neoplasm. ( Condie, A; Leonard, RC; Prosser, J; Weir-Thompson, E, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weir-Thompson, E | 1 |
| Condie, A | 1 |
| Leonard, RC | 1 |
| Prosser, J | 1 |
1 other study available for hydroxylamine and Retinoblastoma
| Article | Year |
|---|---|
A familial RB1 mutation detected by the HOT technique is homozygous in a second primary neoplasm.
Topics: Adult; Base Sequence; Carcinoma, Small Cell; Exons; Eye Neoplasms; Female; Genes, Retinoblastoma; Ge | 1991 |