hydroxylamine has been researched along with Methemoglobinemia in 6 studies
amino alcohol : An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "When given IV in bolus doses to intact anesthetized dogs or cats, hydroxylamine hydrochloride produced transient but precipitous falls in the mean arterial blood pressure in a dose-related manner, as well as a significant methemoglobinemia." | 3.67 | Hypotensive effects of hydroxylamine in intact anesthetized dogs and cats. ( Doherty, PA; Kruszyna, H; Kruszyna, R; Smith, RP, 1984) |
| " HS and PHZ proved to be more toxic to the rabbit than to the rat although both chemicals produced similar hematological effects at equivalent dose levels within the same species." | 1.27 | Toxicity of hydroxylamine sulfate following dermal exposure: variability with exposure method and species. ( Babich, PC; Derelanko, MJ; Gad, SC; Gavigan, FA; Rinehart, WE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CRICK, J | 1 |
| JACKSON, H | 1 |
| ARNOLDOVA, KA | 1 |
| SPERANSKII, NN | 1 |
| Kruszyna, R | 2 |
| Kruszyna, H | 2 |
| Doherty, PA | 1 |
| Smith, RP | 2 |
| Bhattacharya, R | 1 |
| Sugendran, K | 1 |
| Derelanko, MJ | 1 |
| Gad, SC | 1 |
| Gavigan, FA | 1 |
| Babich, PC | 1 |
| Rinehart, WE | 1 |
6 other studies available for hydroxylamine and Methemoglobinemia
| Article | Year |
|---|---|
The selective localization of p-radioiodophenyl-hydroxylamine in red cells: its relation to methaemoglobinaemia.
Topics: Erythrocytes; Humans; Hydroxylamine; Hydroxylamines; Methemoglobinemia; Physiological Phenomena | 1953 |
[SOME ASPECTS OF THE EFFECT OF HYDROXYLAMINE HYDROCHLORIDE ON THE ANIMAL BODY].
Topics: Anemia; Animals; Drug Hypersensitivity; Female; Guinea Pigs; Humans; Hydroxylamine; Hydroxylamines; | 1963 |
Hypotensive effects of hydroxylamine in intact anesthetized dogs and cats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dogs; Female; Hydroxylamine; Hyd | 1984 |
Comparison of hydroxylamine, 4-dimethylaminophenol and nitrite protection against cyanide poisoning in mice.
Topics: Aminophenols; Animals; Antibodies; Cyanides; Cytochrome-B(5) Reductase; Humans; Hydroxylamine; Hydro | 1982 |
Biochemical changes induced by two new prophylactic regimens for cyanide antagonism.
Topics: Aminophenols; Anemia, Hemolytic; Animals; Antidotes; Cyanides; Drug Evaluation, Preclinical; Hydroxy | 1992 |
Toxicity of hydroxylamine sulfate following dermal exposure: variability with exposure method and species.
Topics: Administration, Topical; Animals; Erythrocyte Count; Female; Hemolysis; Hydroxylamine; Hydroxylamine | 1987 |