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hydroxylamine and Methemoglobinemia

hydroxylamine has been researched along with Methemoglobinemia in 6 studies

amino alcohol : An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group.

Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"When given IV in bolus doses to intact anesthetized dogs or cats, hydroxylamine hydrochloride produced transient but precipitous falls in the mean arterial blood pressure in a dose-related manner, as well as a significant methemoglobinemia."3.67Hypotensive effects of hydroxylamine in intact anesthetized dogs and cats. ( Doherty, PA; Kruszyna, H; Kruszyna, R; Smith, RP, 1984)
" HS and PHZ proved to be more toxic to the rabbit than to the rat although both chemicals produced similar hematological effects at equivalent dose levels within the same species."1.27Toxicity of hydroxylamine sulfate following dermal exposure: variability with exposure method and species. ( Babich, PC; Derelanko, MJ; Gad, SC; Gavigan, FA; Rinehart, WE, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CRICK, J1
JACKSON, H1
ARNOLDOVA, KA1
SPERANSKII, NN1
Kruszyna, R2
Kruszyna, H2
Doherty, PA1
Smith, RP2
Bhattacharya, R1
Sugendran, K1
Derelanko, MJ1
Gad, SC1
Gavigan, FA1
Babich, PC1
Rinehart, WE1

Other Studies

6 other studies available for hydroxylamine and Methemoglobinemia

ArticleYear
The selective localization of p-radioiodophenyl-hydroxylamine in red cells: its relation to methaemoglobinaemia.
    British journal of pharmacology and chemotherapy, 1953, Volume: 8, Issue:1

    Topics: Erythrocytes; Humans; Hydroxylamine; Hydroxylamines; Methemoglobinemia; Physiological Phenomena

1953
[SOME ASPECTS OF THE EFFECT OF HYDROXYLAMINE HYDROCHLORIDE ON THE ANIMAL BODY].
    Gigiena truda i professional'nye zabolevaniia, 1963, Volume: 7

    Topics: Anemia; Animals; Drug Hypersensitivity; Female; Guinea Pigs; Humans; Hydroxylamine; Hydroxylamines;

1963
Hypotensive effects of hydroxylamine in intact anesthetized dogs and cats.
    Archives of toxicology, 1984, Volume: 55, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dogs; Female; Hydroxylamine; Hyd

1984
Comparison of hydroxylamine, 4-dimethylaminophenol and nitrite protection against cyanide poisoning in mice.
    Archives of toxicology, 1982, Volume: 49, Issue:3-4

    Topics: Aminophenols; Animals; Antibodies; Cyanides; Cytochrome-B(5) Reductase; Humans; Hydroxylamine; Hydro

1982
Biochemical changes induced by two new prophylactic regimens for cyanide antagonism.
    Biochemistry international, 1992, Volume: 26, Issue:4

    Topics: Aminophenols; Anemia, Hemolytic; Animals; Antidotes; Cyanides; Drug Evaluation, Preclinical; Hydroxy

1992
Toxicity of hydroxylamine sulfate following dermal exposure: variability with exposure method and species.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 8, Issue:4

    Topics: Administration, Topical; Animals; Erythrocyte Count; Female; Hemolysis; Hydroxylamine; Hydroxylamine

1987